CN106309353A - Ointment used for treating psoriasis and preparation method thereof - Google Patents
Ointment used for treating psoriasis and preparation method thereof Download PDFInfo
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- CN106309353A CN106309353A CN201510341717.7A CN201510341717A CN106309353A CN 106309353 A CN106309353 A CN 106309353A CN 201510341717 A CN201510341717 A CN 201510341717A CN 106309353 A CN106309353 A CN 106309353A
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- ointment
- solution
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- sorbester
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Abstract
The invention relates to an ointment used for treating psoriasis. The ointment with a novel prescription is formed based on improvement of an original (sold on the market) prescription. The ointment comprises the following components by weight ratio: 1-10 parts of span 80, 10-20 parts of lightweight liquid paraffin, 70-90 parts of white Vaseline, and 0.0002-0.001 parts of main drug. The ointment with the novel prescription has the advantages of low cost, medicinal requirement accordance, and good compatibility of original accessory, and the method has the advantages of safe process, environmental protection, and no stimulation on skin.
Description
Technical field
The present invention relates to one and treat psoriatic ointment, be specifically related to ointment and the preparation technology thereof of a kind of novel prescription.
Background technology
The psoriatic ointment for the treatment of sold at home at present mostly is Japan and other countries import, and its prescription includes the adjuvants such as diisopropyl adipate (DIPA).And there is following several defect when practical operation as adjuvant in diisopropyl adipate (DIPA): 1, the domestic registration code without this adjuvant pharmaceutical grade, it is impossible to use；2, this adjuvant is usually used in industrial product, such as cosmetics, but in medicine, needs to purify to medicinal rank, and its process is complicated, and technique is loaded down with trivial details, thus adds the cost of medicine.
Summary of the invention
The technical problem to be solved is to provide one can substitute the adjuvant of diisopropyl adipate (DIPA), thus form a kind of ointment having novel prescription, its each prescription have cheap, to meet medicinal requirements, the supplementary material compatibility good, manufacturing process is safe and environment-friendly, to the advantage such as skin is non-stimulated.
The ointment novel prescription composition of the present invention and the weight proportion of each composition be: sorbester p17 1～10 parts, light liquid petrolatum 10～20 parts, white vaseline 70～90 parts, principal agent 0.0002～0.001 part.
The preparation method of above-mentioned ointment comprises the following steps:
A. prepare solution I: added by principal agent in sorbester p17, fully dissolve and stir, obtain solution I；
B. prepare solution II: added by light liquid petrolatum in solution I, stir, obtain solution II；
C. in solution II, add the white vaseline of molten, continue stirring until fully mixing under 50 DEG C of insulations, obtain ointment finished product.
The present invention is the psoriatic ointment for the treatment of after prescription is improved, and has the advantage that compared with commercially available ointment
(1) the low new adjuvant of the use (sorbester p17) that is easy to get of valency instead of original adjuvant (DIPA), both in the formulation role similar, the former is easier to obtain, cheap, the latter this be industrial grade product, purification process is loaded down with trivial details, takes time and effort consumption money；(2) the most each relevant medicine of the pharmaceutical grade product of degree of knowing well height sorbester p17 commonly uses, thus approved by masses；(3) after the improvement of reliability height prescription, ointment seldom causes the uncomfortable reactions such as allergy.
Detailed description of the invention
Embodiment 1
It is on the waiting list following supplementary material by weight:
Sorbester p17 3g, light liquid petrolatum 17g, white vaseline 80 g, principal agent 0.0008g
Its manufacturing process comprises the following steps:
A. prepare solution I: added by principal agent in sorbester p17, fully dissolve and stir, obtain solution I；
B. prepare solution II: added by light liquid petrolatum in solution I, stir, obtain solution II；
C. in solution II, add the white vaseline of molten, continue stirring until fully mixing under 50 DEG C of insulations, obtain ointment finished product.
Embodiment 2
It is on the waiting list following supplementary material by weight
Sorbester p17 8g, light liquid petrolatum 15g, white vaseline 77 g, principal agent 0.0008g
Its manufacturing process comprises the following steps:
A. prepare solution I: added by principal agent in sorbester p17, fully dissolve and stir, obtain solution I；
B. prepare solution II: added by light liquid petrolatum in solution I, stir, obtain solution II；
C. in solution II, add the white vaseline of molten, continue stirring until fully mixing under 50 DEG C of insulations, obtain ointment finished product.
Embodiment 3
It is on the waiting list following supplementary material by weight
Sorbester p17 10g, light liquid petrolatum 20g, white vaseline 70 g, principal agent 0.0008g
Its manufacturing process comprises the following steps:
A. prepare solution I: added by principal agent in sorbester p17, fully dissolve and stir, obtain solution I；
B. prepare solution II: added by light liquid petrolatum in solution I, stir, obtain solution II；
C. in solution II, add the white vaseline of molten, continue stirring until fully mixing under 50 DEG C of insulations, obtain ointment finished product.
Claims (2)
1. treat psoriatic ointment for one kind, it is characterised in that the weight proportion of formulation and each composition is: sorbester p17 1～10 parts, light liquid petrolatum 10～20 parts, white vaseline 70～90 parts, principal agent 0.0002～0.001 part.
2. treat psoriatic ointment preparation method for one kind, it is characterised in that include following step: (1) prepares solution I: is added by principal agent in sorbester p17, fully dissolves and stir, and obtains solution I；(2) prepare solution II: added by light liquid petrolatum in solution I, stir, obtain solution II；(3) in solution II, add the white vaseline of molten, continue stirring until fully mixing under 50 DEG C of insulations, obtain ointment finished product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510341717.7A CN106309353A (en) | 2015-06-19 | 2015-06-19 | Ointment used for treating psoriasis and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510341717.7A CN106309353A (en) | 2015-06-19 | 2015-06-19 | Ointment used for treating psoriasis and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106309353A true CN106309353A (en) | 2017-01-11 |
Family
ID=57733592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510341717.7A Pending CN106309353A (en) | 2015-06-19 | 2015-06-19 | Ointment used for treating psoriasis and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106309353A (en) |
Citations (12)
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|---|---|---|---|---|
| CN1059468A (en) * | 1990-09-04 | 1992-03-18 | 藤泽药品工业株式会社 | The ointment that contains tricyclic compound |
| CN1315192A (en) * | 2000-03-30 | 2001-10-03 | 陈江辉 | Ointment for treating psoriasis and its preparing process |
| CN1478478A (en) * | 2002-12-06 | 2004-03-03 | 重庆华邦制药股份有限公司 | Medicinal composition for treating psoriasis |
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| CN1939319A (en) * | 2005-09-28 | 2007-04-04 | 江苏正大天晴药业股份有限公司 | Isoglycyrrhiza acid magnesium externally-applied preparation, its making method and usage |
| CN101422427A (en) * | 2005-09-28 | 2009-05-06 | 江苏正大天晴药业股份有限公司 | Magnesium isoglycyrrhizinate cream and preparation method and use thereof |
| CN102641275A (en) * | 2012-05-16 | 2012-08-22 | 江苏圣宝罗药业有限公司 | Compound clobetasol propionate and tretinoin ointment |
| CN102805724A (en) * | 2011-08-31 | 2012-12-05 | 山东方明药业集团股份有限公司 | Vitamin A acid cream and preparation method thereof |
| CN103349663A (en) * | 2013-03-19 | 2013-10-16 | 江苏圣宝罗药业有限公司 | Compound clobetasol propionate lipid composite ointment and preparation method thereof |
| CN103877166A (en) * | 2014-01-16 | 2014-06-25 | 王雅冬 | Medicine composition for treating psoriasis |
| CN105534996A (en) * | 2016-02-24 | 2016-05-04 | 长沙佰顺生物科技有限公司 | Medicine composition for treating psoriasis |
-
2015
- 2015-06-19 CN CN201510341717.7A patent/CN106309353A/en active Pending
Patent Citations (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1059468A (en) * | 1990-09-04 | 1992-03-18 | 藤泽药品工业株式会社 | The ointment that contains tricyclic compound |
| CN1315192A (en) * | 2000-03-30 | 2001-10-03 | 陈江辉 | Ointment for treating psoriasis and its preparing process |
| CN1478478A (en) * | 2002-12-06 | 2004-03-03 | 重庆华邦制药股份有限公司 | Medicinal composition for treating psoriasis |
| CN1517092A (en) * | 2003-01-17 | 2004-08-04 | 江苏圣宝罗药业有限公司 | Compound preparation fortreating psoriasis vulgaris and its preparation process |
| CN1939319A (en) * | 2005-09-28 | 2007-04-04 | 江苏正大天晴药业股份有限公司 | Isoglycyrrhiza acid magnesium externally-applied preparation, its making method and usage |
| CN101422427A (en) * | 2005-09-28 | 2009-05-06 | 江苏正大天晴药业股份有限公司 | Magnesium isoglycyrrhizinate cream and preparation method and use thereof |
| CN1742742A (en) * | 2005-10-09 | 2006-03-08 | 王卫阳 | Amikacin paste and preparing method and use |
| CN102805724A (en) * | 2011-08-31 | 2012-12-05 | 山东方明药业集团股份有限公司 | Vitamin A acid cream and preparation method thereof |
| CN102641275A (en) * | 2012-05-16 | 2012-08-22 | 江苏圣宝罗药业有限公司 | Compound clobetasol propionate and tretinoin ointment |
| CN103349663A (en) * | 2013-03-19 | 2013-10-16 | 江苏圣宝罗药业有限公司 | Compound clobetasol propionate lipid composite ointment and preparation method thereof |
| CN103877166A (en) * | 2014-01-16 | 2014-06-25 | 王雅冬 | Medicine composition for treating psoriasis |
| CN105534996A (en) * | 2016-02-24 | 2016-05-04 | 长沙佰顺生物科技有限公司 | Medicine composition for treating psoriasis |
Non-Patent Citations (2)
| Title |
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| 山西省立医院编: "《实用药物手册》", 31 May 1987 * |
| 靳茜婷等: "抗银屑病药物Y316 外用制剂的筛选及处方研究", 《华西药学杂志》 * |
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Application publication date: 20170111 |