CN106308738A - Device and method for detecting glaucoma - Google Patents

Device and method for detecting glaucoma Download PDF

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Publication number
CN106308738A
CN106308738A CN201610761245.5A CN201610761245A CN106308738A CN 106308738 A CN106308738 A CN 106308738A CN 201610761245 A CN201610761245 A CN 201610761245A CN 106308738 A CN106308738 A CN 106308738A
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resistance
transporting discharging
integrated transporting
display
detection
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CN201610761245.5A
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CN106308738B (en
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何良义
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MEDCONOVA MEDICAL TECHNOLOGY Co Ltd
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MEDCONOVA MEDICAL TECHNOLOGY Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
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  • Ophthalmology & Optometry (AREA)
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  • Heart & Thoracic Surgery (AREA)
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  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

The invention relates to the technical field of medical diagnosis, in particular to a device and method for detecting glaucoma. The device for detecting glaucoma comprises an over-table display mechanism, an under-table detection mechanism and an installation connector connected with the over-table display mechanism and the under-table detection mechanism. The over-table display mechanism comprises a front shell, an image displayer, a camera shooting monitor, a medical displayer and a camera shooting monitoring displayer, wherein the image displayer, the camera shooting monitor, the medical displayer and the camera shooting monitoring displayer are arranged on the front shell, the medical displayer is electrically connected with the image displayer, and the camera shooting monitoring displayer is electrically connected with the camera shooting monitor. The image displayer and the camera shooting monitor are arranged on the front shell through a first installation support, and the medical displayer and the camera shooting monitoring displayer are arranged on the front shell through a second installation support. The device can relieve the pain of a patient in the detection process and is high in detection speed, small in time consumption and high in detection accuracy; various kinds of specific detection equipment can be reasonably arranged, and the detection process is made simple, convenient and user-friendly.

Description

A kind of device and method for glaucoma detection
Technical field
The present invention relates to medical diagnostic techniqu field, a kind of device and method for glaucoma detection.
Background technology
Glaucoma is a kind of ophthalmic diseases, and its morbidity is rapid, hazardness is big.Its reason is intraocular pressure intermittently or continually property liter The high horizontal exceeding eyeball tolerant degree of institute and bring infringement to eyeball each several part tissue and visual performance, cause optic nerve Atrophy, constriction of visual field, visual deterioration, the blind simply time sooner or later, within 24-48 hour, can lose completely at acute attack stage Bright.
Therefore, diagnose glaucoma in time, accurately particularly significant, the discovery state of an illness the most as early as possible, could take in time Measure, Authorization Notice No. is CN201888807U, bulletin is opened the Chinese invention patent that day is on July 16th, 2011 and disclosed portable Formula glaucoma rapid-screening analyser, it is mainly stimulated screen, monitoring camera-shooting dress by industrial computer, LED brightness controlling device, the visual field Put, transponder and printer are constituted, described industrial computer respectively with LED brightness controlling device, camera monitoring device, transponder and Printer connects, and described LED brightness controlling device stimulates screen to be connected with light-dividing device and the visual field successively, its by industrial computer and LED lamp control device carries out communication, controls LED lamp luminous intensity, and according to glaucoma rapid-screening analysis strategy, it is right to complete The analysis of testing result.Such detection mode, very big to the stimulation of eyes, during detection, patient is the most painful, detection time Between very long need 30 minutes, the accuracy of detection is the highest, and various equipment is placed desultorily, is unfavorable for the inspection of reality Survey operation.
Summary of the invention
The present invention is directed to the problem that prior art exists, it is proposed that a kind of can alleviate the misery of patient during detection, Detection speed soon, the shortest, Detection accuracy is high, additionally it is possible to reasonably arranges various specific detection equipment, makes detection process Easy, the device for glaucoma detection of hommization and the method using this device detection glaucoma.
The technical solution adopted for the present invention to solve the technical problems is: a kind of device for glaucoma detection, including Table top indication mechanism and Tai Xia testing agency, and connect the installation of described table top indication mechanism and described Tai Xia testing agency even Fitting;
Described table top indication mechanism includes fore shell, be arranged on the image display on described fore shell, camera monitor and with institute State the medical display that image display is electrically connected with and the monitoring camera-shooting display being electrically connected with described camera monitor;Institute State image display and described camera monitor to be arranged on described fore shell by the first installing rack, described medical display and institute State monitoring camera-shooting display to be arranged on described fore shell by the second installing rack;
Described Tai Xia testing agency includes moving body, is arranged on the mesochite on described moving body surface, and is arranged on described Detection within moving body controls equipment;
Described detection control equipment includes computer processor and computer storage, described computer processor and described image Display and described medical display are electrically connected with, and control described image display and show the visual stimulus figure for patient view Shape, controls that described medical display record detects from the one or more electrodes being arranged on patient's scalp, in response to institute State the Visual Evoked Potential Signal of visual stimulus figure, and show in described medical display according to described Visual Evoked Potential Signal Show the analysis result of glaucoma;
Described visual stimulus figure is produced by the separation grid stimulus signal generation module being arranged in described image display, institute State visual stimulus figure and include stimulating graphic model 1, its stimulation time interval ISI=20ms ~ 60ms, grating contrast C=8% With stimulation graphic model 2, its stimulation time interval ISI=40ms, grating contrast C=5% ~ 20%;Described stimulation figure mould Formula 1 is provided with stimulation time interval and randomly selects unit;Described stimulation graphic model 2 is provided with grating contrast and randomly selects unit.
The present invention can utilize pictorial displays to demonstrate many group visual stimulus figures, and patient is being observed these figures The Visual Evoked Potential Signal of rear generation, by electrode-feedback to computer processor, and makes doctor's display record and display Testing result, such mode detects, and the injury to eyes is the least, the shortest, it addition, for the attention concentrating patient Power, is also equipped with camera monitor, can be used for doctor simultaneously and monitors patient's figure whether on Observation Figure display. And the equipment that will all detect reasonably is arranged on detection means, during detection can arbitrarily adjusting display device detection height and inspection Measuring angle, doctor need not and then detect device and shifts one's position with patient, and it is convenient to detect, and detection efficiency is high.
As preferably, described medical display includes visual evoked potential logging modle;Described visual evoked potential is charged to Module includes the first amplifying circuit, frequency selection circuit, analog to digital conversion circuit, first control circuit and the first wireless transceiver circuit; Described first amplifying circuit is connected with the electrode being arranged on patient's scalp;Described frequency selection circuit is with described first amplifying circuit even Connect;Analog-digital conversion circuit as described is connected with described frequency selection circuit;Described first control circuit and analog-digital conversion circuit as described and institute State the first wireless transceiver circuit to connect;Described first wireless transceiver circuit communicates with described computer processor.
As preferably, described first amplifying circuit includes that the first order amplifying circuit being of coupled connections successively, the second level are amplified Circuit and third level amplifying circuit;The described first order and third level amplifying circuit are proportional difference amplifying circuit, and described second Level amplifying circuit is high-pass filtering differential amplifier circuit.
As preferably, described first order amplifying circuit includes the first resistance, the second resistance, the 3rd resistance, the first integrated fortune Put and the second integrated transporting discharging;Described second resistance is connected between positive terminal and the exit of the first integrated transporting discharging;Described 3rd Resistance is connected between negative phase end and the exit of the second integrated transporting discharging;Described first resistance is just being connected to the first integrated transporting discharging Mutually between end and the negative phase end of the second integrated transporting discharging;The negative phase end of described first integrated transporting discharging is signal input part, described second The positive terminal ground connection of integrated transporting discharging;
Described second level amplifying circuit includes the 4th resistance, the 5th resistance, the 6th resistance, the 7th resistance, the first electric capacity, the second electricity Hold and the 3rd integrated transporting discharging;It is integrated that the exit of described first integrated transporting discharging passes sequentially through the first electric capacity, the 4th resistance and the 3rd The negative phase end of amplifier connects;It is integrated that the exit of described second integrated transporting discharging passes sequentially through the second electric capacity, the 5th resistance and the 3rd The positive terminal of amplifier connects;Described 6th resistance is connected between negative phase end and the exit of the 3rd integrated transporting discharging;Described 3rd The positive terminal of integrated transporting discharging passes through the 7th resistance eutral grounding;
Described third level amplifying circuit includes the 8th resistance, the 9th resistance and the 4th integrated transporting discharging;Described 3rd integrated transporting discharging The positive terminal of exit and the 4th integrated transporting discharging connects;The negative phase end of described 4th integrated transporting discharging is by the 9th resistance and the 4th collection The exit becoming amplifier connects;The negative phase end of described 4th integrated transporting discharging passes through the 8th resistance eutral grounding;Described 4th integrated transporting discharging The outfan that exit is signal.
As preferably, analog-digital conversion circuit as described includes charge accumulator, current source module, input resistance, comparator, touches Send out device, enumerator, discharge module, clock generation module;Analog voltage signal to be converted connects described through described input resistance The first input end of comparator, the second input of described comparator connects reference voltage;The input of described trigger connects The outfan of comparator;The outfan of described trigger connects input and the discharge module of described enumerator;Described electric charge is deposited Reservoir is connected between the first input end of described comparator and the first fixed level;Described current source module connects comparator First input end;Described discharge module is connected between the first input end of described comparator and the second fixed level;Time described Clock generation module connects trigger sum counter.
As preferably, described input resistance be Standard resistance range be the swept resistance of 5-20 K Ω.
As preferably, described first installing rack includes support bar, the support arm being connected with described support bar, with described support The regulating arm that arm connects, and the mounting head being connected with described regulating arm;Described support arm one end has the described support bar of socket Opening, the other end have the threaded openings one of threaded described regulating arm;It is provided with described bottom described regulating arm one end Threaded openings one with the use of nipple one, the other end have the threaded openings two of threaded described mounting head;Described Be provided with bottom mounting head one end with described threaded openings two with the use of nipple two, the other end is provided with installation diagram picture and shows The installing plate of device.
As preferably, described second installing rack includes mounting rod, and the first support arm being connected with described mounting rod, with described First mounting head of the first support arm connection and the first regulating arm, and the second mounting head being connected with described first regulating arm; Have in the middle of described first support arm and be socketed the accent of described mounting rod, two ends have threaded described first mounting head The first hickey and the second hickey with described first regulating arm;Have with described bottom described first regulating arm one end Second hickey with the use of the second nipple, the other end have the 3rd screw thread of threaded described second mounting head Interface;Be provided with bottom described second mounting head one end with described 3rd hickey with the use of the 3rd nipple, another End is provided with the second installing plate installing described monitoring camera-shooting display;It is provided with and described first bottom described first mounting head one end Hickey with the use of the first nipple, the other end be provided with install described medical display the first installing plate.
As preferably, described installation connecting element includes fixing the first linkage section being connected, with described with described mesochite top Mesochite fixes the 3rd linkage section of connection towards patient-side, and contacts with described mesochite surface engagement and connect described respectively First linkage section and described 3rd linkage section two ends and the second linkage section being convexly curved and the 4th linkage section;Described first If linkage section, described second linkage section, described 3rd linkage section and described 4th linkage section are connected side with described fore shell and are provided with Dry installation draw-in groove;Described installation draw-in groove includes the elastic telescopic part being connected with bottom land, is arranged on described elastic telescopic part top Contact block, is arranged on two groups of slide assemblies of draw-in groove both sides, and the reset slide block being connected with described interactive assemblies;Described fore shell Being provided with and the installation fixture block of described installation draw-in groove clamping with described installation connecting element contact side, described installation fixture block has with described The fixing groove that slide assemblies fixes.
A kind of method of glaucoma detection, including:
Step 1: described medical display is connected with the scalp of patient by electrode and passes through described image display and show and regard Feel and stimulate figure to obtain patient's Visual Evoked Potential Signal in response to described visual stimulus figure;
Step 2: the Visual Evoked Potential Signal of described medical display record is carried out discrete Fourier transform (DFT), described to obtain The power spectrum of Visual Evoked Potential Signal;
Step 3: be integrated the power spectrum of described Visual Evoked Potential Signal calculating the frequency to respectively obtain original signal and The frequency of noise, and the signal to noise ratio of described Visual Evoked Potential Signal is determined by the frequency of original signal and the frequency of noise;
Step 4: described signal to noise ratio is compared with preset critical;
Step 5: based on described comparison, determine the probability of glaucoma.
The invention has the beneficial effects as follows:
The most simple eye actually detected being less than 1 minute, eyes all detect operation and complete less than 10 minutes, and experimenter is difficult to tired Labor, is significantly better than the multifocal ERG detection equipment detection time of nearly 2 hours;
2. need not approach operation and mydriasis, decrease the complexity of operation;Graphic interface and computer programing divide automatically Analysis makes this equipment be prone to non-expert level user operation, and operator are not required to train especially or long period of operation experience, meet basic unit Healthcare practitioner's Current Level;
3. use electro physiology means that maincenter optic nerve path directly measured, it is to avoid experimenter and operator are because adapting to water Flat or technology judges the deviation caused;The degree of accuracy of glaucoma detection is high;
4. can detect at common clinic, be not required to special shielding room, to light, temperature, humidity, fatigue etc. at other The interference factor easily occurred in detection means is all without specific restriction.
Accompanying drawing explanation
Fig. 1 is the structural representation of a kind of device for glaucoma detection of the present invention;
Fig. 2 is the structural representation of the first installing rack in Fig. 1;
Fig. 3 is the structural representation of the second installing rack in Fig. 1;
Fig. 4 is the structural representation of installation connecting element in Fig. 1;
Fig. 5 is the structural representation installing draw-in groove in Fig. 4;
Fig. 6 is the flow chart of a kind of method for glaucoma detection of the present invention;
Wherein: 1, table top indication mechanism, 11, fore shell, 12, image display, 13, camera monitor, 14, medical display, 15, Monitoring camera-shooting display, the 16, first installing rack, the 17, second installing rack, 2, Tai Xia testing agency, 21, moving body, 22, in Shell, 3, installation connecting element.
Detailed description of the invention
Further illustrate technical scheme below in conjunction with the accompanying drawings and by detailed description of the invention.
As it is shown in figure 1, a kind of device for glaucoma detection, including table top indication mechanism 1 and Tai Xia testing agency 2, And connect described table top indication mechanism 1 and the installation connecting element 3 of described Tai Xia testing agency 2.Described table top indication mechanism 1 wraps Include fore shell 11, be arranged on the image display 12 on described fore shell 11, camera monitor 13 and with described image display 12 The medical display 14 being electrically connected with and the monitoring camera-shooting display 15 being electrically connected with described camera monitor 13.Described image Display 12 and described camera monitor 13 are arranged on described fore shell 11 by the first installing rack 16, described medical display 14 It is arranged on described fore shell 11 by the second installing rack 17 with described monitoring camera-shooting display 15.
Described Tai Xia testing agency 2 includes moving body 21, is arranged on the mesochite 22 on described moving body 21 surface, and Being arranged on the detection within described moving body 21 and control equipment, be provided with universal wheel bottom moving body 21, vehicle body is provided with handle Hands, can be easy to detect by whole for visual electrophysiology detector random movement.
Described detection control equipment includes computer processor and computer storage, and described computer processor is with described Image display 12 and described medical display 14 are electrically connected with, and described computer processor is by being stored in described Computer Storage Software program in device controls, and controls described image display 12 and shows the visual stimulus figure for patient view, controls institute State medical display 14 record that detect from the one or more electrodes being arranged on patient's scalp, sting in response to described vision Swash the Visual Evoked Potential Signal of figure, and show green light according to described Visual Evoked Potential Signal in described medical display 14 The analysis result of eye.Being referred to as visual evoked potential by visual stimulus signal at the potential response that brain produces, the application uses Electrode collects Visual Evoked Potential Signal, and amplified device amplifies, and is converted into digital signal by digital-to-analogue converter therewith and is sent to Computer carries out storing with data analysis to obtain the probability of glaucoma.
Described visual stimulus figure is by the separation grid stimulus signal generation module being arranged in described image display 12 Produce, use unique separation grid graph to stimulate patient.When the grid of low spatial frequency is with high temporal frequency inversion flicker, The induction producing higher effect of stimulation, beneficially visual signal is produced and can distinguish stimulation and regards god by the visual effect of sighting target M and P cell in ganglion cell, owing to M cell relatively early damages in optic nerve lesion disease, utilizes this technology can Early to identify the infringement of M cell, the generation of prompting optic nerve function damage in early days.The application is by regulation correlated frequency Etc. parameter, it is also possible to further discriminate between and stimulate the "ON" in M cell and two kinds of subgroups of "Off", it is provided that more fully stimulation mode and The fine degree of diagnosis.
Described visual stimulus figure includes stimulating graphic model 1, its stimulation time interval ISI=20ms ~ 60ms, grating pair Ratio degree C=8% and stimulation graphic model 2, its stimulation time interval ISI=40ms, grating contrast C=5% ~ 20%, described Stimulating graphic model 1 to be provided with stimulation time interval and randomly select unit, it is random that described stimulation graphic model 2 is provided with grating contrast Choose unit.When selecting to stimulate graphic model 1, grating contrast C=8%, stimulation time is spaced apart in ISI=20ms ~ 60ms Arbitrary value, i.e. there are 41 submodules;When selecting to stimulate graphic model 2, stimulation time interval ISI=40ms, grating contrasts Degree is the arbitrary value in C=5% ~ 20%, i.e. has 16 submodules.Can be shown by image when selecting visual stimulus figure Device 12 random call submodule, each patient can repeatedly call different submodules to improve glaucoma detection when detecting vision Degree of accuracy.
Described medical display 14 includes visual evoked potential logging modle;Described visual evoked potential is charged to module and is included First amplifying circuit, frequency selection circuit, analog to digital conversion circuit, first control circuit and the first wireless transceiver circuit;Described first Amplifying circuit is connected with the electrode being arranged on patient's scalp, be suitable to electrode detection to Visual Evoked Potential Signal be amplified Process and amplify signal to obtain;Described frequency selection circuit is connected with described first amplifying circuit, is suitable to carry out described amplification signal Frequency-selecting processes to obtain frequency-selecting signal;Analog-digital conversion circuit as described is connected with described frequency selection circuit, is suitable to described frequency-selecting signal Carry out analog-to-digital conversion process to obtain digital sampled signal;Described first control circuit and analog-digital conversion circuit as described and described the One wireless transceiver circuit connects, and is suitable to communicate with described first wireless transceiver circuit;Described first wireless transceiver circuit is fitted In being communicated with described computer processor by radio connection.
The visual evoked potential of the application is charged to and is provided with frequency selection circuit in module, and user can set according to the actual requirements Different frequency collection scopes, so that in the range of useful Visual Evoked Potential Signal is positioned at the frequency collection of setting, thus carry High described visual evoked potential is charged to module and is gathered the accuracy of Visual Evoked Potential Signal, prevents Visual Evoked Potential Signal Distortion.
Visual evoked potential charge to first order amplifying circuit that the first amplifying circuit in module includes being of coupled connections successively, Second level amplifying circuit and third level amplifying circuit.The described first order and third level amplifying circuit are proportional difference and amplify electricity Road, described second level amplifying circuit is high-pass filtering differential amplifier circuit.
Described first order amplifying circuit includes the first resistance, the second resistance, the 3rd resistance, the first integrated transporting discharging and the second collection Becoming amplifier, described second resistance is connected between positive terminal and the exit of the first integrated transporting discharging;Described 3rd resistance is connected to Between negative phase end and the exit of the second integrated transporting discharging;Described first resistance is connected to the positive terminal and second of the first integrated transporting discharging Between the negative phase end of integrated transporting discharging;The negative phase end of described first integrated transporting discharging is signal input part, described second integrated transporting discharging Positive terminal ground connection.
Described second level amplifying circuit include the 4th resistance, the 5th resistance, the 6th resistance, the 7th resistance, the first electric capacity, Two electric capacity and the 3rd integrated transporting discharging, the exit of described first integrated transporting discharging passes sequentially through the first electric capacity, the 4th resistance and the 3rd The negative phase end of integrated transporting discharging connects;The exit of described second integrated transporting discharging passes sequentially through the second electric capacity, the 5th resistance and the 3rd The positive terminal of integrated transporting discharging connects;Described 6th resistance is connected between negative phase end and the exit of the 3rd integrated transporting discharging;Described The positive terminal of the 3rd integrated transporting discharging passes through the 7th resistance eutral grounding.
Described third level amplifying circuit includes the 8th resistance, the 9th resistance and the 4th integrated transporting discharging, described 3rd integrated fortune The exit put and the positive terminal of the 4th integrated transporting discharging connect;The negative phase end of described 4th integrated transporting discharging is by the 9th resistance and the The exit of four integrated transporting dischargings connects;The negative phase end of described 4th integrated transporting discharging passes through the 8th resistance eutral grounding;Described 4th integrated The exit of amplifier is the outfan of signal.
The first amplifying circuit that the visual evoked potential of the application is charged in module can be effectively improved vision induced electricity The amplification of position signal also can weaken other elements to the amplification of Visual Evoked Potential Signal interference, further increases green grass or young crops The degree of accuracy of light eye detection.
The resistance of described first resistance is 200 Ω, the resistance of the second resistance is 450 Ω, the resistance of the 3rd resistance is 450 Ω, the resistance of the 4th resistance are 1.9K Ω, the resistance of the 5th resistance is 1.9K Ω, the resistance of the 6th resistance is 18K Ω, the 7th electricity The resistance of resistance is 18K Ω, the resistance of the 8th resistance is 1.2K Ω, the resistance of the 9th resistance is 12K Ω, and first under this resistance is put The amplification effect of big circuit is best.
Visual evoked potential is charged to the analog to digital conversion circuit in module and is included charge accumulator, current source module, input electricity Resistance, comparator, trigger, enumerator, discharge module, clock generation module;Analog voltage signal to be converted is through described input Resistance connects the first input end of described comparator, and the second input of described comparator connects reference voltage;Described trigger Input connect comparator outfan;The outfan of described trigger connects input and the electric discharge mould of described enumerator Block;Described charge accumulator is connected between the first input end of described comparator and the first fixed level;Described current source mould Block connects the first input end of comparator;Described discharge module is connected to first input end and the second fixing electricity of described comparator Between Ping;Described clock generation module connects trigger sum counter;Described charge accumulator is electric capacity.The modulus of the application turns Change circuit production low cost, capacity of resisting disturbance by force, further increase the detection degree of accuracy of glaucoma.
Input resistance in analog to digital conversion circuit be Standard resistance range be the swept resistance of 5-20 K Ω, input resistance is not solid Fixed, but can be adjusted according to actually detected environment, prevent changing distorted signals serious, further increase glaucoma Detection degree of accuracy.
As shown in fig. 4-5, it is provided with installation connecting element 3 between described fore shell 11 and described mesochite 22.Described installation connects Part 3 includes fixing, with described mesochite 22 top, the first linkage section being connected, and fixes towards patient-side with described mesochite 22 and to be connected 3rd linkage section, and contact and connect respectively described first linkage section and the described 3rd with described mesochite 22 surface engagement even The section of connecing two ends and the second linkage section being convexly curved and the 4th linkage section.Table top indication mechanism 1 is made by installation connecting element 3 More convenient with Tai Xia testing agency 2 installing/dismounting.Described first linkage section, described second linkage section, described 3rd linkage section And described 4th linkage section is welded to each other successively.During installation, the first linkage section and the 3rd linkage section are fixed on the conjunction of mesochite Right position is put, then fore shell 11 is arranged on the surface of installation connecting element 3 make fore shell 11 and the first linkage section, the second linkage section, Three linkage sections and the 4th linkage section connect, and fore shell 11 will be made to securely fix with mesochite 22, will not be shifted over, and when installing not Can make mistakes.
Described first linkage section, described second linkage section, described 3rd linkage section and described 4th linkage section are with described Fore shell 11 connects side and is provided with some installation draw-in grooves.Described installation draw-in groove includes the elastic telescopic part being connected with bottom land, is arranged on institute State the contact block at elastic telescopic part top, be arranged on two groups of slide assemblies of draw-in groove both sides, and be connected with described interactive assemblies Reset slide block.
Described slide assemblies includes the guide rail one being arranged on bottom land and is arranged on the first sliding shoe on described guide rail one, The guide rail two that is arranged on sidewall and be arranged on the second sliding shoe on described guide rail two, the guide rail three being arranged on roof with And it being arranged on the 3rd sliding shoe on described guide rail three, described first sliding shoe, the second sliding shoe and the 3rd sliding shoe mutually lead System is slided.
Described fore shell 11 is provided with and the installation fixture block of described installation draw-in groove clamping, institute with described installation connecting element 3 contact side State installation fixture block and have the fixing groove entered for described 3rd sliding shoe.
During installation, first the notch of draw-in groove it is installed by installing card block alignment and contacts with contact block, the most firmly pressing fore shell 11 elasticity of compression extensible members make installation fixture block enter inside draw-in groove, and contact block and the first sliding shoe contact and promote first to slide simultaneously Motion block is to two Slideslips from guide rail one, and the first sliding shoe of movement promotes the second sliding shoe upward sliding on guide rail two, enters One step makes fore shell 11 and installation connecting element 3 in promoting the 3rd sliding shoe to slide on guide rail three and entering the fixing groove installing fixture block Securely fix.
During dismounting, by reset slide block to two Slideslips, the 3rd sliding shoe is driven to make the 3rd sliding shoe leave to two Slideslips Fixing groove, install fixture block depart from the 3rd sliding shoe spacing after outwards ejected by elastic telescopic part immediately, reach fore shell 11 The purpose separated with installation connecting element 3, the second sliding shoe and the first sliding shoe return to original under the promotion of the 3rd sliding shoe Position.
Described contact block is provided with and the circular surface of described first shoe contact, and the setting of circular surface decreases two slide blocks Between friction, reduce the degree of wear of slide block.Described first slide block is provided with and contacts with described contact block and tilt with bottom land The angle inclined plane more than 60 degree, and the circular surface contacted with described the second sliding shoe, inclined-plane arranges and increases horizontal component i.e. Increasing the motive force to the first slide block, the setting of circular surface decreases the friction between two slide blocks, reduces the mill of slide block Damage degree.Described the second sliding shoe is provided with the inclined plane contacting with described first sliding shoe and being more than 60 degree with sidewall draft angles, And the circular surface contacted with described 3rd sliding shoe, inclined-plane arranges and increases vertical stress component and i.e. increase and push away the second slide block Power, the setting of circular surface decreases the friction between two slide blocks, reduces the degree of wear of slide block.Described 3rd sliding shoe Being provided with the inclined plane contacting with described the second sliding shoe and being more than 60 with roof inclination angle, inclined-plane arranges and increases horizontal component i.e. Increase the motive force to the 3rd slide block.
As in figure 2 it is shown, described first installing rack 16 includes support bar, the support arm being connected with described support bar, with described The regulating arm that support arm connects, and the mounting head being connected with described regulating arm.Described support arm one end has described of socket The opening of strut, the other end have the threaded openings one of threaded described regulating arm;Be provided with bottom described regulating arm one end with Described threaded openings one with the use of nipple one, the other end have the threaded openings two of threaded described mounting head; Be provided with bottom described mounting head one end with described threaded openings two with the use of nipple two, the other end be provided with installation diagram picture The installing plate of display.
When specifically installing, first the threaded openings one of support arm is threadeded with the nipple one of regulating arm, then will The threaded openings two of regulating arm is threadeded with the nipple two of mounting head, and support arm is then enclosed within the suitable position of support bar Put and fix, furthermore regulating the relative angle between support arm and regulating arm and regulating arm and mounting head according to demand, After by image display fixedly mount on a mounting board.During use, image display and camera monitor can be according to patients Physical location regulation detection angles, detection and convenient, there is the feature of hommization.
As it is shown on figure 3, described second installing rack 17 includes mounting rod, the first support arm being connected with described mounting rod, with First mounting head of described first support arm connection and the first regulating arm, and the second installation being connected with described first regulating arm Head.Have in the middle of described first support arm and be socketed the accent of described mounting rod, two ends have threaded described first peace Fill head and the first hickey of described first regulating arm and the second hickey;Have bottom described first regulating arm one end with Described second hickey with the use of the second nipple, the other end have the 3rd of threaded described second mounting head Hickey;Be provided with bottom described second mounting head one end with described 3rd hickey with the use of the 3rd nipple, The other end is provided with the second installing plate installing described monitoring camera-shooting display;It is provided with described bottom described first mounting head one end First hickey with the use of the first nipple, the other end be provided with install described medical display the first installing plate.
When specifically installing, first the first nipple of the first mounting head and the first hickey of the first support arm are connected Connect, the second nipple of the first regulating arm and the second hickey of the first support arm are connected;Then, by the second mounting head The 3rd nipple and the first regulating arm the 3rd hickey connect;Then, the first support arm is enclosed within mounting rod suitable Position on and fix, furthermore regulate according to demand the first support arm and the first regulating arm and the first mounting head and first regulation Relative angle between arm and the second mounting head;Finally, medical display is fixedly mounted on the first installing plate, shooting is supervised Control display is fixedly mounted on the second installing plate.During use, medical display and monitoring camera-shooting display can be according to doctors Protecting the operating position regulation work angle of personnel, it is the most convenient to operate, and can improve the work efficiency of doctor.
As shown in Figure 6, disclosed herein as well is a kind of glaucoma detection method, including: step 1: described medical science is shown Device 14 is connected with the scalp of patient by electrode and is passed through described image display 12 and shows that visual stimulus figure is to obtain patient Visual Evoked Potential Signal in response to described visual stimulus figure;Step 2: the vision of described medical display 14 record is lured Send out electric potential signal and carry out discrete Fourier transform (DFT), to obtain the power spectrum of described Visual Evoked Potential Signal;Step 3: to described The power spectrum of Visual Evoked Potential Signal is integrated calculating the frequency of frequency and noise to respectively obtain original signal, and passes through The frequency of original signal and the frequency of noise determine the signal to noise ratio of described Visual Evoked Potential Signal;Step 4: by described signal to noise ratio with Preset critical compares;Step 5: based on described comparison, determine the probability of glaucoma.
The figure that stimulates shown by image display 12 is excited the Visual Evoked Potential Signal data obtained, and is shown by medical science Show that device 14 is recorded and stored in computer storage, and carry out processing and profit followed by discrete Fourier transform (DFT) Carry out being calculated the signal to noise ratio of Visual Evoked Potential Signal with integral algorithm.The signal to noise ratio calculated is compared with marginal value Produce a result-glaucoma probability high (positive test result) or low (negative testing result).The method can automatically remove artefact With divorced signal, decrease tedious work and the error in judgement of operator.Data can also preserved in conjunction with computer system With while printer output detections result, the test result of each eyes of instant playback on computer screen, for operation Personnel judge in time, decide whether to proceed next operation sequence.Whole analysis system enhances man-machine interaction, to detection The criterion of result is simple, greatly reduces the judgement operation in the past needing the more professional's experience that relies on, detection visitor The property seen promotes further.
Embodiment described above is only to be described the preferred embodiment of the present invention, the not design to the present invention It is defined with scope.On the premise of without departing from design concept of the present invention, this area ordinary person technical side to the present invention Various modification that case is made and improvement, all should drop into protection scope of the present invention, the technology contents that the present invention is claimed, Through all recording in detail in the claims.

Claims (10)

1. the device for glaucoma detection, it is characterised in that: include table top indication mechanism (1) and Tai Xia testing agency , and connect the installation connecting element (3) of described table top indication mechanism (1) and described Tai Xia testing agency (2) (2);
Described table top indication mechanism (1) includes fore shell (11), the image display (12) that is arranged on described fore shell (11), shooting Watch-dog (13) and the medical display (14) being electrically connected with described image display (12) and with described camera monitor (13) the monitoring camera-shooting display (15) being electrically connected with;Described image display (12) and described camera monitor (13) are by the One installing rack (16) is arranged on described fore shell (11), and described medical display (14) and described monitoring camera-shooting display (15) lead to Cross the second installing rack (17) to be arranged on described fore shell (11);
Described Tai Xia testing agency (2) includes moving body (21), is arranged on the mesochite (22) on described moving body (21) surface, And it is arranged on the detection control equipment that described moving body (21) is internal;
Described detection control equipment includes computer processor and computer storage, described computer processor and described image Display (12) and described medical display (14) are electrically connected with, and control described image display (12) display for patient view Visual stimulus figure, control described medical display (14) record from the one or more electrodes being arranged on patient's scalp visit Visual Evoked Potential Signal that measure, in response to described visual stimulus figure, and exist according to described Visual Evoked Potential Signal The analysis result of described medical display (14) display glaucoma;
Described visual stimulus figure is produced by the separation grid stimulus signal generation module being arranged in described image display (12) Raw, described visual stimulus figure includes stimulating graphic model 1, its stimulation time interval ISI=20ms ~ 60ms, grating contrast C =8% is spaced ISI=40ms, grating contrast C=5% ~ 20% with stimulation graphic model 2, its stimulation time;Described stimulation is schemed Shape pattern 1 is provided with stimulation time interval and randomly selects unit;Described stimulation graphic model 2 is provided with grating contrast and randomly selects list Unit.
A kind of device for glaucoma detection, it is characterised in that: described medical display (14) Including visual evoked potential logging modle;Described visual evoked potential is charged to module and is included the first amplifying circuit, frequency selection circuit, mould Number conversion circuit, first control circuit and the first wireless transceiver circuit;Described first amplifying circuit be arranged on patient's scalp Electrode connect;Described frequency selection circuit is connected with described first amplifying circuit;Analog-digital conversion circuit as described and described frequency selection circuit Connect;Described first control circuit is connected with analog-digital conversion circuit as described and described first wireless transceiver circuit;Described first nothing Line transmission circuit communicates with described computer processor.
A kind of device for glaucoma detection, it is characterised in that: described first amplifying circuit bag Include first order amplifying circuit, second level amplifying circuit and the third level amplifying circuit being of coupled connections successively;The described first order and Three-stage amplifier is proportional difference amplifying circuit, and described second level amplifying circuit is high-pass filtering differential amplifier circuit.
A kind of device for glaucoma detection, it is characterised in that: described first order amplifying circuit Including the first resistance, the second resistance, the 3rd resistance, the first integrated transporting discharging and the second integrated transporting discharging;Described second resistance is connected to Between positive terminal and the exit of the first integrated transporting discharging;Described 3rd resistance is connected to negative phase end and the extraction of the second integrated transporting discharging Between end;Described first resistance is connected between the positive terminal of the first integrated transporting discharging and the negative phase end of the second integrated transporting discharging;Described The negative phase end of the first integrated transporting discharging is signal input part, the positive terminal ground connection of described second integrated transporting discharging;
Described second level amplifying circuit includes the 4th resistance, the 5th resistance, the 6th resistance, the 7th resistance, the first electric capacity, the second electricity Hold and the 3rd integrated transporting discharging;It is integrated that the exit of described first integrated transporting discharging passes sequentially through the first electric capacity, the 4th resistance and the 3rd The negative phase end of amplifier connects;It is integrated that the exit of described second integrated transporting discharging passes sequentially through the second electric capacity, the 5th resistance and the 3rd The positive terminal of amplifier connects;Described 6th resistance is connected between negative phase end and the exit of the 3rd integrated transporting discharging;Described 3rd The positive terminal of integrated transporting discharging passes through the 7th resistance eutral grounding;
Described third level amplifying circuit includes the 8th resistance, the 9th resistance and the 4th integrated transporting discharging;Described 3rd integrated transporting discharging The positive terminal of exit and the 4th integrated transporting discharging connects;The negative phase end of described 4th integrated transporting discharging is by the 9th resistance and the 4th collection The exit becoming amplifier connects;The negative phase end of described 4th integrated transporting discharging passes through the 8th resistance eutral grounding;Described 4th integrated transporting discharging The outfan that exit is signal.
A kind of device for glaucoma detection, it is characterised in that: analog-digital conversion circuit as described bag Include charge accumulator, current source module, input resistance, comparator, trigger, enumerator, discharge module, clock generation module; Analog voltage signal to be converted connects the first input end of described comparator, the second of described comparator through described input resistance Input connects reference voltage;The input of described trigger connects the outfan of comparator;The outfan of described trigger is even Connect input and the discharge module of described enumerator;Described charge accumulator is connected to the first input end and of described comparator Between one fixed level;Described current source module connects the first input end of comparator;Described discharge module is connected to described ratio Between first input end and second fixed level of relatively device;Described clock generation module connects trigger sum counter.
A kind of device for glaucoma detection, it is characterised in that: described input resistance is resistance Scope is the swept resistance of 5-20 K Ω.
A kind of device for glaucoma detection, it is characterised in that: described first installing rack (16) Including support bar, the support arm being connected with described support bar, the regulating arm being connected with described support arm, and with described regulating arm The mounting head connected;Described support arm one end has and is socketed the opening of described support bar, the other end has threaded described tune The threaded openings one of joint arm;Be provided with bottom described regulating arm one end with described threaded openings one with the use of nipple one, The other end has the threaded openings two of threaded described mounting head;It is provided with and described threaded openings bottom described mounting head one end Two with the use of nipple two, the other end be provided with install image display installing plate.
A kind of device for glaucoma detection, it is characterised in that: described second installing rack (17) Including mounting rod, the first support arm being connected with described mounting rod, the first mounting head being connected with described first support arm and One regulating arm, and the second mounting head being connected with described first regulating arm;Socket is had described in the middle of described first support arm The accent of mounting rod, two ends have threaded described first mounting head and the first hickey of described first regulating arm With the second hickey;Have bottom described first regulating arm one end with described second hickey with the use of the second screw thread Joint, the other end have the 3rd hickey of threaded described second mounting head;Set bottom described second mounting head one end Have with described 3rd hickey with the use of the 3rd nipple, the other end is provided with and installs described monitoring camera-shooting display Second installing plate;Be provided with bottom described first mounting head one end with described first hickey with the use of the first screw thread connect Head, the other end are provided with the first installing plate installing described medical display.
A kind of device for glaucoma detection, it is characterised in that: described installation connecting element (3) Fix, including with described mesochite (22) top, the first linkage section being connected, fix towards patient-side with described mesochite (22) and to be connected 3rd linkage section, and contact with described mesochite (22) surface engagement and connect described first linkage section and the described 3rd respectively Linkage section two ends and the second linkage section being convexly curved and the 4th linkage section;Described first linkage section, described second connection Section, described 3rd linkage section and described 4th linkage section are connected side with described fore shell (11) and are provided with some installation draw-in grooves;Described The elastic telescopic part that draw-in groove includes being connected with bottom land is installed, is arranged on the contact block at described elastic telescopic part top, is arranged on card Two groups of slide assemblies of groove both sides, and the reset slide block being connected with described interactive assemblies;Described fore shell (11) and described installation Connector (3) contact side is provided with and the installation fixture block of described installation draw-in groove clamping, and described installation fixture block has and described Slide Group The fixing groove that part fixes.
10. wanting in 1-9, according to right, the method that the device described in any one claim carries out glaucoma detection, its feature exists In: including:
Step 1: described medical display (14) is passed through electrode and is connected with the scalp of patient and passes through described image display (12) display visual stimulus figure is to obtain patient's Visual Evoked Potential Signal in response to described visual stimulus figure;
Step 2: the Visual Evoked Potential Signal recording described medical display (14) carries out discrete Fourier transform (DFT), to obtain The power spectrum of described Visual Evoked Potential Signal;
Step 3: be integrated the power spectrum of described Visual Evoked Potential Signal calculating the frequency to respectively obtain original signal and The frequency of noise, and the signal to noise ratio of described Visual Evoked Potential Signal is determined by the frequency of original signal and the frequency of noise;
Step 4: described signal to noise ratio is compared with preset critical;
Step 5: based on described comparison, determine the probability of glaucoma.
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CN108413198A (en) * 2018-05-15 2018-08-17 郑州大学 Adaptive pinpoint visual stimulator

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