CN106266504A - 一种润肺止咳的中药 - Google Patents

一种润肺止咳的中药 Download PDF

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CN106266504A
CN106266504A CN201610833343.5A CN201610833343A CN106266504A CN 106266504 A CN106266504 A CN 106266504A CN 201610833343 A CN201610833343 A CN 201610833343A CN 106266504 A CN106266504 A CN 106266504A
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陈亚平
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Abstract

本发明涉及一种润肺止咳的中药，包括如下质量份数的原料：川贝母12~16份、甘草3~8份、白屈菜3~5份、枇杷叶6~15份、甜杏仁2~4份、山麦冬5~8份、紫苏叶7~11份、金银花10~13份、桑叶4~6份和山豆根3~5份。各组份协同作用，相得益彰，纯中药制剂，无毒副作用，用于治疗阴虚血热、口干烦渴、咽喉肿痛病症，具有平喘化痰、润肺止咳、清痰、降火，安全、无毒副作用、效果好的特点，该发明治疗周期短，不易复发。

Description

一种润肺止咳的中药
技术领域
本发明涉及中药领域，具体涉及一种润肺止咳的中药。
背景技术
咳嗽是呼吸道疾病最常见的一种症状，咳嗽是人体一种保护性防御功能，通过咳嗽，可以排出呼吸道的分泌物或侵入气管内的衣物，仅有咳嗽而无痰的称为干咳，可见于多种疾病。常见的慢性咽炎，咽部干燥，有瘙痒感和不适感，并由此刺激发出咳声。咳嗽会引起咽后壁粘膜表面粗糙，有许多扩张的小血管，严重时会有透明的小白泡，不及时治疗的话，渐渐地由慢性咽炎转变成肺结核。痰是由细菌、灰尘及气管分泌物共同形成的，经常有痰液滞留在体内，不仅会使呼吸道至病原生长繁殖，导致炎症的滋生并恶化，还易阻塞支气管，发生缺氧、呼吸困难的情况。现有药物中，有的对风寒咳嗽患者不能使用，有的药物则味道甘苦，还有的伤及胃肾，不能使患者得到全面的治疗。
发明内容
针对现有技术的不足，本发明提供一种具有平喘化痰、润肺止咳、清痰、降火，安全、无毒副作用的润肺止咳的中药。
本发明的技术方案是这样实现的：一种润肺止咳的中药，包括如下质量份数的原料：川贝母12~16份、甘草3~8份、白屈菜3~5份、枇杷叶6~15份、甜杏仁2~4份、山麦冬5~8份、紫苏叶7~11份、金银花10~13份、桑叶4~6份和山豆根3~5份。
所述的润肺止咳的中药的制备方法包括以下步骤：
（1） 将川贝母、甜杏仁和山豆根粉碎成粗粉，按照粗粉总重量的5~7倍加入体积浓度为65%的乙醇溶液，回流提纯2~3次，合并提纯液，回收乙醇，减压浓缩至相对密度为1.2~1.3的混料，干燥，粉碎，过100目筛，得到混料细粉A；
（2） 将甘草、白屈菜、枇杷叶、山麦冬、紫苏叶、金银花和桑叶混合放入紫砂锅中，加入相对于上述混合药材质量3~4倍的清水，浸泡6~8个小时，熬制90~120分钟，过滤，取得滤液；将滤液减压浓缩至相对密度为1.2~1.3，干燥，粉碎，得到混料细粉B，将混料细粉B与步骤（1）中的混料细粉A进行充分混合，制得本发明的中药。
川贝母: 苦、甘，微寒。归肺、心经。清热润肺，化痰止咳，散结消痈。用于肺热燥咳，干咳少痰，阴虚劳嗽，痰中带血，瘰疬，乳痈，肺痈。
甘草: 甘，平。归心、肺、脾、胃经。补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
白屈菜: 苦，凉；有毒。归肺、胃经。解痉止痛，止咳平喘。用于胃脘挛痛，咳嗽气喘，百日咳。
枇杷叶: 苦，微寒。归肺、胃经。清肺止咳，降逆止呕。用于肺热咳嗽，气逆喘急，胃热呕逆，烦热口渴。
甜杏仁: 甘，平。归肺、大肠经。润肺止咳平喘，润肠通便。用于肺虚咳喘，肠燥便秘。
山麦冬: 甘、微苦，微寒。归心、肺、胃经。养阴生津，润肺清心。用于肺燥干咳，阴虚痨嗽，喉痹咽痛，津伤口渴，内热消渴，心烦失眠，肠燥便秘。
紫苏叶：辛，温。归肺、脾经。解表散寒，行气和胃。用于风寒感冒，咳嗽呕恶，妊娠呕吐，鱼蟹中毒。
金银花：甘，寒。归肺、心、胃经。清热解毒，疏散风热。用于痈肿疔疮，喉痹，丹毒，热毒血痢，风热感冒，温病发热。
桑叶：甘、苦，寒。归肺、肝经。疏散风热，清肺润燥，清肝明目。用于风热感冒，肺热燥咳，头晕头痛，目赤昏花。
山豆根：苦，寒；有毒。归肺、胃经。清热解毒，消肿利咽。用于火毒蕴结，乳蛾喉痹，咽喉肿痛，牙龈肿痛，口舌生疮。
本发明具有如下的积极效果：各组份协同作用，相得益彰，纯中药制剂，无毒副作用，用于治疗阴虚血热、口干烦渴、咽喉肿痛病症，具有平喘化痰、润肺止咳、清痰、降火，安全、无毒副作用、效果好的特点，该发明治疗周期短，不易复发。
具体实施方式
实施例一
一种润肺止咳的中药，包括如下质量份数的原料：川贝母12份、甘草3份、白屈菜3份、枇杷叶6份、甜杏仁2份、山麦冬5份、紫苏叶7份、金银花10份、桑叶4份和山豆根3份。
制备方法包括以下步骤：（1）将川贝母、甜杏仁和山豆根粉碎成粗粉，按照粗粉总重量的5倍加入体积浓度为65%的乙醇溶液，回流提纯2次，合并提纯液，回收乙醇，减压浓缩至相对密度为1.2的混料，干燥，粉碎，过100目筛，得到混料细粉A；（2）将甘草、白屈菜、枇杷叶、山麦冬、紫苏叶、金银花和桑叶混合放入紫砂锅中，加入相对于上述混合药材质量3倍的清水，浸泡8个小时，熬制90分钟，过滤，取得滤液；将滤液减压浓缩至相对密度为1.2，干燥，粉碎，得到混料细粉B，将混料细粉B与步骤（1）中的混料细粉A进行充分混合，制得本发明的中药。
实施例二
一种润肺止咳的中药，包括如下质量份数的原料：川贝母14份、甘草5份、白屈菜4份、枇杷叶8份、甜杏仁3份、山麦冬6份、紫苏叶9份、金银花12份、桑叶5份和山豆根4份。
制备方法包括以下步骤：（1）将川贝母、甜杏仁和山豆根粉碎成粗粉，按照粗粉总重量的6倍加入体积浓度为65%的乙醇溶液，回流提纯2次，合并提纯液，回收乙醇，减压浓缩至相对密度为1.2的混料，干燥，粉碎，过100目筛，得到混料细粉A；（2）将甘草、白屈菜、枇杷叶、山麦冬、紫苏叶、金银花和桑叶混合放入紫砂锅中，加入相对于上述混合药材质量3倍的清水，浸泡6个小时，熬制120分钟，过滤，取得滤液；将滤液减压浓缩至相对密度为1.2，干燥，粉碎，得到混料细粉B，将混料细粉B与步骤（1）中的混料细粉A进行充分混合，制得本发明的中药。
实施例三
一种润肺止咳的中药，包括如下质量份数的原料：川贝母16份、甘草8份、白屈菜5份、枇杷叶15份、甜杏仁4份、山麦冬8份、紫苏叶11份、金银花13份、桑叶6份和山豆根5份。
制备方法包括以下步骤：（1）将川贝母、甜杏仁和山豆根粉碎成粗粉，按照粗粉总重量的7倍加入体积浓度为65%的乙醇溶液，回流提纯3次，合并提纯液，回收乙醇，减压浓缩至相对密度为1.3的混料，干燥，粉碎，过100目筛，得到混料细粉A；（2）将甘草、白屈菜、枇杷叶、山麦冬、紫苏叶、金银花和桑叶混合放入紫砂锅中，加入相对于上述混合药材质量4倍的清水，浸泡8个小时，熬制120分钟，过滤，取得滤液；将滤液减压浓缩至相对密度为1.3，干燥，粉碎，得到混料细粉B，将混料细粉B与步骤（1）中的混料细粉A进行充分混合，制得本发明的中药。
各组份协同作用，相得益彰，纯中药制剂，无毒副作用，用于治疗阴虚血热、口干烦渴、咽喉肿痛病症，具有平喘化痰、润肺止咳、清痰、降火，安全、无毒副作用、效果好的特点，该发明治疗周期短，不易复发。
本发明的中药可制成冲剂，每袋5g，兑开水200ml使用，每天2次，一周为一个疗程。
使用本发明对100例咳嗽患者进行临床观察治疗，100例病例中男性54例，女性为46例，年龄在15~20岁的45例，20~30岁的20例，30~40岁的20例，40~50岁的15例。其中咳嗽、吐白色泡沫痰，粘稠不易咳出，终日咳嗽者62例，白天间断咳嗽者26例，晚睡体位改变吸入冷空气或剧烈活动后有阵发性咳嗽者12例。所有病例均平素身体健康，无特殊病史。
疗效标准：根据《中药新药临床指导原则》制订的标准。 （１）治愈：咳嗽基本消失；（２）显效：轻微咳嗽，痰量较少，容易咳出；（３）有效：咳嗽减轻，痰量较多，容易咳出；（４）无效：咳嗽基本无改变或稍微减轻，痰量较多，不易咳出，影响夜间睡眠。
治疗结果：100病例经过治疗，其中66例于四个疗程内痊愈，29例于五个疗程内痊愈，5例于六个疗程4周内痊愈，总痊愈率100％。

Claims (2)

1.一种润肺止咳的中药，其特征在于：包括如下质量份数的原料：川贝母12~16份、甘草3~8份、白屈菜3~5份、枇杷叶6~15份、甜杏仁2~4份、山麦冬5~8份、紫苏叶7~11份、金银花10~13份、桑叶4~6份和山豆根3~5份。
2.根据权利要求1所述的润肺止咳的中药，其特征在于：所述的润肺止咳的中药的制备方法包括以下步骤：
(1)将川贝母、甜杏仁和山豆根粉碎成粗粉，按照粗粉总重量的5~7倍加入体积浓度为65%的乙醇溶液，回流提纯2~3次，合并提纯液，回收乙醇，减压浓缩至相对密度为1.2~1.3的混料，干燥，粉碎，过100目筛，得到混料细粉A；
(2)将甘草、白屈菜、枇杷叶、山麦冬、紫苏叶、金银花和桑叶混合放入紫砂锅中，加入相对于上述混合药材质量3~4倍的清水，浸泡6~8个小时，熬制90~120分钟，过滤，取得滤液；将滤液减压浓缩至相对密度为1.2~1.3，干燥，粉碎，得到混料细粉B，将混料细粉B与步骤（1）中的混料细粉A进行充分混合，制得本发明的中药。
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