CN106264535A - Main stream-type people's End-tidal carbon dioxide concentration measuring method - Google Patents

Main stream-type people's End-tidal carbon dioxide concentration measuring method Download PDF

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CN106264535A
CN106264535A CN201610815135.2A CN201610815135A CN106264535A CN 106264535 A CN106264535 A CN 106264535A CN 201610815135 A CN201610815135 A CN 201610815135A CN 106264535 A CN106264535 A CN 106264535A
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voltage
passage
value
crest
data
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CN106264535B (en
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杨嘉琛
周建雄
范大勇
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Tianjin University
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Tianjin University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/083—Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
    • A61B5/0836—Measuring rate of CO2 production
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Physiology (AREA)
  • Surgery (AREA)
  • Computer Vision & Pattern Recognition (AREA)
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  • Artificial Intelligence (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention relates to a kind of main stream-type people's End-tidal carbon dioxide concentration measuring method, including: two passages output modulation waveform concordance regulation parameters when acquisition is not breathed；During sampling, to Measurement channel magnitude of voltage and reference channel magnitude of voltage ALTERNATE SAMPLING, respectively in each channel acquisition data, it is filtered the data gathered processing, filter burst noise, then each remaining sampled data is ranked up, crest value data set is obtained maximum as the sampled value at this crest；In like manner valley value data set is being obtained minima as the sampled value at this trough；Calculate the amplitude value information of each passage；Two passage initial magnitude are carried out uniformity compensation；According to rating test, obtain fitting parameter, obtain current breathing CO2 concentration.The present invention can improve certainty of measurement.

Description

Main stream-type people's End-tidal carbon dioxide concentration measuring method
Technical field
The invention belongs to biomedical engineering field, for relating to a kind of people's End-tidal carbon dioxide concentration accurately side of monitoring Method.
Background technology
During in the medical monitorings such as clinic, people breathes, gas concentration lwevel is monitored in real time and is increasingly come into one's own, and especially exhales End carbon dioxide dividing potential drop becomes six basic vital signss.It is currently based on the End-tidal carbon dioxide concentration of NDIR principle Monitoring systematic survey can be divided mainly into two kinds: main stream-type measured directly monitoring and the side stream type measured by extraction breathing gas Monitoring.
Extraction gas dehumidification, voltage stabilizing can be made certainty of measurement higher by side stream type monitoring, but prolonging due to extraction air-flow Time make display waveform have obvious distortion and equipment is comparatively laborious.And main stream-type monitoring can be divided into thermopile sensor to supervise mostly Survey and pyroelectric sensor is monitored, although thermopile sensor monitoring can make circuit power stable, but due to respiratory air flow Interference makes monitoring result error relatively big, and drifting problem the most easily occurs in waveform when long-time monitoring continuously.Pyroelectricity senses Device occurs so that Monitoring Performance is greatly improved, and it has sensing wave-length coverage width, fast response time, and stable performance etc. is excellent Point, but it is weak to there is also output signal, easily by problems such as circuit noise interference.
Although current main-stream formula carbon dioxide monitoring technology is fast accordingly, stable performance, but precision is the highest, measures process loaded down with trivial details Phenomenon yet suffer from, and measure process relatively low herein for people's End-tidal carbon dioxide concentration, to measuring process and method Improve, thus improve certainty of measurement.
Summary of the invention
It is an object of the invention to overcome current main-stream formula carbon dioxide monitoring technology acuracy the highest, loaded down with trivial details the showing of measurement process As, it is provided that main stream-type people's End-tidal carbon dioxide concentration measuring method that a kind of certainty of measurement is higher.Technical scheme is as follows:
A kind of main stream-type people's End-tidal carbon dioxide concentration measuring method, comprises the following steps:
1) reference channel and the peak-to-peak value of two passage output modulation waveforms of Measurement channel are measured under normal circumstances at waveform, Then two passages are carried out consistency analysis, try to achieve two passage output modulation waveform concordance regulation parameters when not breathing K1, k2；
2) respiration test is carried out, when dual pathways pyroelectric sensor output voltage reaches crest VHOr trough point VLShi Qidong Analog-to-digital conversion device starts area sampling；
3) during sampling, to Measurement channel magnitude of voltage and reference channel magnitude of voltage ALTERNATE SAMPLING, respectively at each channel acquisition The data gathered are filtered processing, filter burst noise, then arrange each remaining sampled data by data Sequence, obtains maximum as the sampled value at this crest to crest value data set；In like manner valley value data set is being obtained minimum Value is as the sampled value at this trough；
4) reception size of data is judged available Measurement channel crest voltage VMHWith valley point voltage VML；And reference Channel peak voltage VRHWith valley point voltage VRL；
5) amplitude value information of each passage, i.e. Measurement channel U are calculatedM=VMH-VML, reference channel is UR=VRH-VRL；
6) two passage initial magnitude are carried out uniformity compensation, i.e.
7) according to rating test, obtain fitting parameter K, then can obtain breathing CO2 concentration currently:
The present invention is directed to that people's End-tidal carbon dioxide concentration is relatively low and measurement process, measurement process and method are changed Enter, thus improve certainty of measurement.
Accompanying drawing explanation
Fig. 1 main stream-type people breathes end CO2Monitoring modular.
Detailed description of the invention
The gas concentration lwevel monitoring method of the present invention proposes for main stream-type gas-monitoring, the present invention is given below and fits Monitoring system composition.
This main stream-type breathing carbon dioxide density monitoring system is made up of host computer and monitoring modular.Host computer is general meter Calculation machine or monitor.Monitoring modular is as it is shown in figure 1,1 represents light source module, and 2 represent sensor assembly, and 3 is transparent sheet glass, 4 is gas passage.Wherein 3 and 4 constitute pipeline adapter, can be directly installed on people exhaled gas official road.And light source module The discrete both sides in pipeline adapter.Sensor assembly has three passages, is respectively mounted optical filter, wherein at each passway CO2The optical filter of passage is 4.26 μm, and the optical filter of reference channel is 3.95 μm.
Current sensor uses two pass bands scheme, and one of them is Measurement channel, and another passage is reference channel, The problems such as the purpose that reference channel introduces is fixed in order to avoid flashing, components and parts drift, but in the case of initial calibration, two Initial output inconsistent the carrying out that can affect subsequent experimental of modulation waveform amplitude situation of passage, the present invention proposes two passages Consistency analysis, is that two passages carry out initial compensation, it is to avoid error, improves precision.
All according to Lambert-Beer's law in the method for current carbon dioxide concentration measurement, it may be assumed that
I=I0exp(-KcL) (1)
Wherein, I0Being respectively original incident light intensity and exiting light beam intensity with I, c is tested gas concentration, and L is that air chamber is long Degree, K is gas infrared Absorption coefficient.But the method calculates process to light concentration gas measurement error relatively greatly, root herein Breathe out the end relatively low situation of gas concentration lwevel according to people, this measuring method improved, i.e. passes through Taylor expansion:
I=I0(1-KcL) (2)
Thus measurement scheme is adjusted to the output voltage measuring two passages, then voltage is subtracted each other, and than upper reference The voltage of passage, now this magnitude of voltage is linear with exhalation end carbon dioxide concentration value, and by calibration experiment, we just may be used To obtain this linear relationship parameter.
Operating process is:
(1) power-on self-test, when passing through without pipeline airless, turns on the power, and whether checks two passage waveforms of sensor Normally.
(2) measure the peak-to-peak value of two passage output modulation waveforms at waveform under normal circumstances, then two passages are entered Row consistency analysis, tries to achieve two passage output modulation waveform concordance regulation parameters k1, k2 when not breathing.
(3) carrying out respiration test, monitoring modular sends pulse signal and controls light source light on and off, and dual pathways pyroelectric sensor is defeated Going out amplitude continually varying modulated signal, then monitoring modular starts timing wait, when dual pathways pyroelectric sensor output electricity Pressure reaches crest VHOr trough point VLShi Qidong analog-to-digital conversion device starts area sampling；
(4), during sampling, analog-digital converter is to Measurement channel magnitude of voltage and reference channel magnitude of voltage ALTERNATE SAMPLING, respectively often Individual channel acquisition data, the data gathered carry out following preliminary treatment according to 16 one group: first pass through the every passage of removal In 10 data, 3 maximums and 3 minima, filter burst noise, is then ranked up 9 data of each residue, Crest value data set is obtained maximum as the sampled value at this crest；In like manner valley value data set is being obtained minima work For the sampled value at this trough.
(5) result of each passage is sent to host computer；Host computer carries out judging can get to receiving size of data Measurement channel crest voltage VMHWith valley point voltage VML；And reference channel crest voltage VRHWith valley point voltage VRL。
(6) amplitude value information of each passage, i.e. Measurement channel U are calculatedM=VMH-VML, reference channel is UR=VRH-VRL。
(7) two passage initial magnitude are carried out uniformity compensation, i.e.Wherein k1, k2 are not Two passage output modulation waveform concordance regulation parameters during breathing.
(8) according to rating test, obtain fitting parameter K, then can obtain breathing CO2 concentration currently:

Claims (1)

1. a main stream-type people End-tidal carbon dioxide concentration measuring method, comprises the following steps:
1) reference channel and the peak-to-peak value of two passage output modulation waveforms of Measurement channel are measured under normal circumstances at waveform, then Two passages are carried out consistency analysis, tries to achieve two passage output modulation waveform concordance regulation parameters k1, k2 when not breathing；
2) respiration test is carried out, when dual pathways pyroelectric sensor output voltage reaches crest VHOr trough point VLShi Qidong modulus Converter starts area sampling；
3) during sampling, to Measurement channel magnitude of voltage and reference channel magnitude of voltage ALTERNATE SAMPLING, respectively in each channel acquisition data, It is filtered the data gathered processing, filters burst noise, then each remaining sampled data is ranked up, right Crest value data set obtains maximum as the sampled value at this crest；In like manner valley value data set is being obtained minima conduct Sampled value at this trough；
4) reception size of data is judged available Measurement channel crest voltage VMHWith valley point voltage VML；And reference channel peak Threshold voltage VRHWith valley point voltage VRL；
5) amplitude value information of each passage, i.e. Measurement channel U are calculatedM=VMH-VML, reference channel is UR=VRH-VRL；
6) two passage initial magnitude are carried out uniformity compensation, i.e.
7) according to rating test, obtain fitting parameter K, then can obtain breathing CO2 concentration currently:
CN201610815135.2A 2016-09-10 2016-09-10 Main stream-type people's End-tidal carbon dioxide concentration measuring method Active CN106264535B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108931492A (en) * 2018-05-24 2018-12-04 天津大学 Main stream-type people's End-tidal carbon dioxide waveform filtering method
CN113514527A (en) * 2021-07-09 2021-10-19 三诺生物传感股份有限公司 Ion detection method

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CN103705244A (en) * 2013-12-16 2014-04-09 天津大学 Method for synchronously monitoring breath pressure and concentration of carbon dioxide in main flow mode
CN104840201A (en) * 2015-05-14 2015-08-19 天津大学 Main flow type breathing flow real-time monitoring device and method
CN105105750A (en) * 2015-09-15 2015-12-02 天津大学 Main flow type human breathing flow and carbon dioxide concentration simultaneous monitoring device and method
CN105167777A (en) * 2015-09-15 2015-12-23 天津大学 Mainstream type synchronous monitoring device and method for multiple kinds of breathing gas concentrations and breathing gas pressure
CN105232048A (en) * 2015-09-15 2016-01-13 天津大学 Main flow type monitoring device and method for concentration of various respiratory gases

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108931492A (en) * 2018-05-24 2018-12-04 天津大学 Main stream-type people's End-tidal carbon dioxide waveform filtering method
CN113514527A (en) * 2021-07-09 2021-10-19 三诺生物传感股份有限公司 Ion detection method

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