CN106237414A - A kind of vein micro-nano mist oxygen device and oxygen therapy method - Google Patents

A kind of vein micro-nano mist oxygen device and oxygen therapy method Download PDF

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Publication number
CN106237414A
CN106237414A CN201610764260.5A CN201610764260A CN106237414A CN 106237414 A CN106237414 A CN 106237414A CN 201610764260 A CN201610764260 A CN 201610764260A CN 106237414 A CN106237414 A CN 106237414A
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oxygen
vein
transferring
pipe
blood
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CN106237414B (en
Inventor
解启莲
马祖长
徐晓嵘
姚威
张晓明
余洪龙
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Anhui Tongling Bionic Technology Co Ltd
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Anhui Tongling Bionic Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621Constructional aspects thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601Control or regulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1698Blood oxygenators with or without heat-exchangers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/02Gases
    • A61M2202/0208Oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow

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  • Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)

Abstract

A kind of vein micro-nano mist oxygen device and oxygen therapy method, including an oxygen transferring in vein pipe being inserted in vein blood vessel, stretching out, with described oxygen transferring in vein pipe, the control device that venous blood pipe end is connected, this control device is passed through the oxygen concentration in described oxygen transferring in vein pipe for accurately control.By inserting oxygen transferring in vein pipe in vein blood vessel, oxygen is transported to vein blood vessel, walk around diffusing capacity this pass of alveolar and allow oxygen be directly entered blood and with hemoglobin oxygenate, pulmonary can be preferably replaced at lung failure or when temporarily can not play Oxygenation, compared with membrane oxygenator, oxygen carrying succedaneum or liquid oxygen charging method, this apparatus structure is simple, easy to use, be not required to blood drainage to the most external, thus avoid various possible infection, blood oxygen carrying content is high, stability is preferable.

Description

A kind of vein micro-nano mist oxygen device and oxygen therapy method
Technical field
The present invention relates to manually cure by oxygen therapy field, be specifically related to a kind of vein micro-nano mist oxygen device and oxygen therapy method.
Background technology
It is known that the deposit of oxygen is little in human body, it is necessary to continuously feed oxygen from the external world in a steady stream and just can sustain life, Therefore from the most initial mask oxygen inhalation to nose conduit, hyperbaric oxygen chamber and the Ventilators etc. the most in succession occurred all It is conceived to by respiratory tract oxygen supply, and has become the important means of various anoxia treatment.But, for some particular patients ', often Rule oxygen supply method can seem helpless.Such as in the face of the acute lung injury caused due to Serious respiratory tract burn etc., traumatic Hypertonicity pulmonary edema that hydropneumothorax, sea water cause, SARS etc. cause the patient of pulmonary diffusion function serious hindrance, and its subject matter is also Do not lie in dysfunction of ventilation, therefore usually cannot effectively save the life of patient through conventional respiratory tract oxygen supply;Meanwhile, special at some In the case of, the restriction of conventional oxygen supply method also rescue to patient brings many obstacles.So, oxygen supply approach can be changed, Attempt waiting as supplemental oxygen new method by vein is even oral, walk around this pass of alveolar of diffusing capacity and make oxygen straight Tap into into blood?
In fact recent domestic never stops about the research in terms of oxygen carrying succedaneum, such as without substrate blood egg In vain, the circulating protein solution of genetic engineering artificial blood, liposome parcel, perfluorocarbon solution etc., but due to these product process Complicated, expensive, also have relatively large distance from technology maturation so far, be still difficult to use in clinic.And once should be used in China Liquid oxygen charging method then includes light quantum blood therapy (UIB), blood-magent therapy, magnesium arginyl amine hydroperoxide Carbamide Peroxide method, light quantum Liquid treatment etc., but be also respectively present blood drawing oxygenation and feed back some defects such as operation is loaded down with trivial details, blood oxygen carrying content few, less stable.
Summary of the invention
The present invention solves the problems referred to above, it is provided that a kind of vein micro-nano mist oxygen device and oxygen therapy method thereof.
The technical problem to be solved uses following technical scheme to realize:
A kind of vein micro-nano mist oxygen device, this vein micro-nano mist oxygen device includes that a vein being inserted in vein blood vessel is defeated Oxygen pipe, stretches out, with described oxygen transferring in vein pipe, the control device that venous blood pipe end is connected, and this control device is passed through for accurately control Oxygen pressure in described oxygen transferring in vein pipe.
Described control device includes oxygen catheter, effusion meter, piezometer, controller, control panel;Described oxygen transferring in vein pipe end End is connected with described oxygen catheter front end by a flexible pipe, is positioned at vein blood vessel outer end at oxygen transferring in vein pipe and is provided with piezometer, institute Stating piezometer to be connected with described controller, described controller is connected with described control panel, is provided with effusion meter on oxygen catheter, Described effusion meter is connected with controller, and oxygen catheter front end is provided with bypass branch, equipped with control valve in this bypass branch, controls Valve is connected with controller.
Insert vein blood vessel front and back end at oxygen transferring in vein pipe and be respectively arranged with blood inlet end blood oxygen concentration measuring instrument, hemorrhage end blood Oxygen concentration testing instrument, blood inlet end blood oxygen concentration measuring instrument, hemorrhage end blood oxygen concentration measuring instrument be connected respectively to controller, and vein is defeated Oxygen pipe inserts vein blood vessel part forward end seal, is evenly distributed with nanoscale oxygen therapy hole along central axis, and described oxygen therapy hole becomes cone Shape and summit are positioned at central axis, and oxygen transferring in vein pipe lateral wall is made up of semipermeable membrane, and semipermeable membrane allows gas to pass through, and liquid is not Can pass through, be oxygen therapy passage at oxygen transferring in vein tube hub, oxygen therapy channel end is oxygen inlet, and oxygen therapy passage cures by oxygen therapy hole with taper Connection, oxygen enters into oxygen therapy hole, the oxygen oxygen in oxygen therapy bore end i.e. semipermeable membrane outer wall and vein blood vessel from oxygen therapy passage Close, for the most effectively controlling oxygen flow and improving oxygenation efficiency, be unlikely to because the oxygen in oxygen transferring in vein pipe is too much or very few Cause that to form oxygen content in oxygen bubbles or blood in vein blood vessel too low, when oxygen transferring in vein tube section area is that vein blood vessel cuts The 0.6-0.8 of face area, when oxygen therapy channel radius is the 0.1-0.3 of oxygen transferring in vein pipe radius, from the oxygen of oxygen therapy hole ejection both Having higher pressure makes oxygen content in blood the highest through semipermeable membrane, does not has again the generation of oxygen bubbles simultaneously.
A kind of oxygen transferring in vein method, comprises the following steps:
1), described oxygen transferring in vein pipe is inserted in vein blood vessel, and carries out the back works such as hemostasis sterilization;
2), set on described control panel and be passed through oxygen transferring in vein pipe oxygen pressure as a setting value;
3), described control panel transfer signals to controller, controller controls effusion meter and opens and to oxygen transferring in vein pipe Interior conveying oxygen, the blood in vein blood vessel and the oxygen in oxygen transferring in vein pipe are at semipermeable membrane outer wall oxygenate, and piezometer is supervised simultaneously Oxygen pressure in control oxygen transferring in vein pipe, keeps flow to be calculated as an opening angle, during oxygenate, if going out when reaching setting value The oxygen pressure that existing piezometer records is higher than setting value, and signal is first fed back to controller by piezometer, and controller sends opens control Valve order, control valve is opened an angle and makes the oxygen pressure in oxygen transferring in vein pipe gradually reduce, and when being reduced to setting value, controls Device sends closing control valve order, if occurring, the oxygen pressure that piezometer records is less than setting value, and signal is fed back to control by piezometer Device processed, controller sends increase effusion meter opening angle order, until the oxygen pressure in oxygen transferring in vein pipe is equal to setting value;
4), during oxygenate, oxygen transferring in vein pipe inserts the blood inlet end blood oxygen concentration measuring instrument of vein blood vessel front and back end, goes out Oxygen content in forward and backward for the oxygenate recorded blood is fed back to controller and shows in control by blood end blood oxygen concentration measuring instrument respectively Panel, medical personnel revise the setting value of oxygen pressure in oxygen transferring in vein pipe accordingly.
The invention have the benefit that by inserting oxygen transferring in vein pipe in vein blood vessel, oxygen is transported to venous blood Pipe, walk around diffusing capacity this pass of alveolar and allow oxygen be directly entered blood and with hemoglobin oxygenate, decline at pulmonary function Pulmonary can be preferably replaced, with membrane oxygenator, oxygen carrying succedaneum or liquid when exhausting or temporarily can not play Oxygenation Body oxygen charging method is compared, and this apparatus structure is simple, easy to use, be not required to blood drainage to the most external, thus avoids various possibility Infection, blood oxygen carrying content is high, stability is preferable.
Accompanying drawing explanation
Fig. 1 is schematic diagram of the present invention;
Fig. 2 is the profilograph that oxygen transferring in vein pipe inserts vein blood vessel part.
Detailed description of the invention
For the technological means making the present invention realize, creation characteristic, reach purpose and be easy to understand with effect, below knot Close embodiment, the present invention is expanded on further.
As it is shown in figure 1, a kind of vein micro-nano mist oxygen device, including oxygen transferring in vein pipe 2, effusion meter 8, piezometer 3, controller 6, control panel 7;Oxygen transferring in vein pipe 2 front end is inserted in vein blood vessel 1, at its end by flexible pipe 12 and oxygen catheter 9 front end Connecting, be positioned at vein blood vessel 1 outer end at oxygen transferring in vein pipe 2 and be provided with piezometer 3, piezometer 3 is connected with controller 6, controller 6 Be connected with control panel 7, piezometer 3 in monitoring oxygen transferring in vein pipe 2 in real time oxygen pressure and by the data feedback recorded to controlling Device processed, oxygen catheter 9 is provided with effusion meter 8, and effusion meter 8 is passed through the oxygen flow in oxygen transferring in vein pipe 2, effusion meter 8 for control It is connected with controller 6, oxygen catheter 9 front end is provided with bypass branch 11, equipped with control valve 10 in bypass branch 11, control valve 10 It is connected with controller 6, when the oxygen pressure in oxygen transferring in vein pipe is higher than setting value, makes vein by the opening angle of control valve 10 Oxygen pressure in oxygen catheter 2 is reduced to setting value and turns off control valve 10.
Insert vein blood vessel 1 front and back end at oxygen transferring in vein pipe 2 and be respectively arranged with blood inlet end blood oxygen concentration measuring instrument 5, hemorrhage End blood oxygen concentration measuring instrument 4, blood inlet end blood oxygen concentration measuring instrument 5, hemorrhage end blood oxygen concentration measuring instrument 4 are connected respectively to controller 6, oxygen transferring in vein pipe 2 inserts vein blood vessel part forward end seal, is evenly distributed with nanoscale oxygen therapy hole 13, oxygen therapy along central axis Hole 13 is tapered and summit is positioned at central axis, and oxygen transferring in vein pipe 2 lateral wall is made up of semipermeable membrane 16, and semipermeable membrane 16 allows gas Body passes through, and liquid can not pass through, and at oxygen transferring in vein pipe 2 center for oxygen therapy passage 14, oxygen therapy passage 14 end is oxygen inlet 15, Oxygen therapy passage 14 connects with taper oxygen therapy hole 13, and oxygen enters into oxygen therapy hole 13 from oxygen therapy passage 14, at oxygen therapy hole 13 end i.e. Oxygen oxygenate in semipermeable membrane 16 outer wall and vein blood vessel, for the most effectively controlling oxygen flow and improving oxygenation efficiency, unlikely In too much because of the oxygen in oxygen transferring in vein pipe or very few cause that to form oxygen content in oxygen bubbles or blood in vein blood vessel too low, As the 0.6-0.8 that oxygen transferring in vein tube section area is vein blood vessel area of section, oxygen therapy passage 14 radius is oxygen transferring in vein pipe half During the 0.1-0.3 in footpath, from the oxygen of oxygen therapy hole 13 ejection, both there is higher pressure and had made oxygen content blood through semipermeable membrane 16 The highest, there is no again the generation of oxygen bubbles simultaneously.
A kind of oxygen transferring in vein method, comprises the following steps:
1), oxygen transferring in vein pipe 2 is inserted in vein blood vessel 1, and carries out the back works such as hemostasis sterilization;
2), set on control panel 7 and be passed through oxygen transferring in vein pipe 2 oxygen pressure as a setting value;
3), control panel 7 transfer signals to controller 6, controller 6 controls effusion meter 8 and opens and to oxygen transferring in vein pipe 2 Interior conveying oxygen, the blood in vein blood vessel 1 and the oxygen in oxygen transferring in vein pipe 2 are at semipermeable membrane 16 outer wall oxygenate, pressure simultaneously Oxygen pressure in meter 3 monitoring oxygen transferring in vein pipe, keeping effusion meter 8 when reaching setting value is an opening angle, in oxygenate process In, if occurring, the oxygen pressure that piezometer 3 records is higher than setting value, and signal is first fed back to controller 6, controller 6 by piezometer 3 Going out to open control valve 10 to order, control valve 10 is opened an angle and makes the oxygen pressure in oxygen transferring in vein pipe 2 gradually reduce, and works as reduction During to setting value, controller 6 sends closing control valve 10 and orders, if occurring, the oxygen pressure that piezometer 3 records is less than setting value, pressure Signal is fed back to controller 6 by power meter 3, and controller 6 sends increase effusion meter 8 opening angle order, until in oxygen transferring in vein pipe 2 Oxygen pressure equal to setting value;
4), during oxygenate, oxygen transferring in vein pipe 2 insert vein blood vessel front and back end blood inlet end blood oxygen concentration measuring instrument 5, Oxygen content in forward and backward for the oxygenate recorded blood is fed back to controller 6 and shows by hemorrhage end blood oxygen concentration measuring instrument 4 respectively Control panel 7, medical personnel revise the setting value of oxygen pressure in oxygen transferring in vein pipe 2 accordingly.
The ultimate principle of the present invention, principal character and advantages of the present invention have more than been shown and described.The technology of the industry The personnel only present invention it should be appreciated that the present invention is not restricted to the described embodiments, described in above-described embodiment and description Preference, be not intended to limit the present invention, without departing from the spirit and scope of the present invention, the present invention also has various Changes and improvements, these changes and improvements both fall within scope of the claimed invention.Claimed scope is by institute Attached claims and equivalent thereof define.

Claims (7)

1. a vein micro-nano mist oxygen device, it is characterised in that: this vein micro-nano mist oxygen device includes that one is inserted into vein blood vessel In oxygen transferring in vein pipe, stretch out, with described oxygen transferring in vein pipe, the control device that venous blood pipe end is connected, this control device for essence Really control to be passed through the oxygen flow in described oxygen transferring in vein pipe.
2. a kind of vein micro-nano mist oxygen device as claimed in claim 1, it is characterised in that: described control device includes oxygen therapy Pipe, effusion meter, piezometer, controller, control panel;Described oxygen transferring in vein pipe end is by a flexible pipe and described oxygen catheter front end Connecting, be positioned at vein blood vessel outer end at oxygen transferring in vein pipe and be provided with piezometer, described piezometer is connected with described controller, controls Device is connected with described control panel, is provided with effusion meter on oxygen catheter, and described effusion meter is connected with controller, before oxygen catheter End is provided with bypass branch, and equipped with control valve in this bypass branch, control valve is connected with controller.
3. a kind of vein micro-nano mist oxygen device as claimed in claim 2, it is characterised in that: described oxygen transferring in vein pipe inserts vein Blood vessel front and back end is respectively arranged with blood inlet end blood oxygen concentration measuring instrument, hemorrhage end blood oxygen concentration measuring instrument, described blood inlet end blood oxygen Concentration measuring apparatus, hemorrhage end blood oxygen concentration measuring instrument are connected with described controller respectively.
4. a kind of vein micro-nano mist oxygen device as claimed in claim 1, it is characterised in that: described oxygen transferring in vein pipe inserts vein Vasculature part leading portion seals, and is evenly distributed with nanoscale oxygen therapy hole along central axis, and described oxygen therapy hole is tapered and summit is positioned at At central axis, oxygen transferring in vein pipe lateral wall is made up of semipermeable membrane, and semipermeable membrane allows gas to pass through, and liquid can not pass through, quiet Arteries and veins oxygen catheter center is oxygen therapy passage, and oxygen therapy channel end is oxygen inlet, and oxygen therapy passage connects with described taper oxygen therapy hole.
5. a kind of vein micro-nano mist oxygen device as claimed in claim 4, it is characterised in that: described oxygen transferring in vein tube section area 0.6-0.8 for vein blood vessel area of section.
6. a kind of vein micro-nano mist oxygen device as described in claim 4 or 5, it is characterised in that: described oxygen therapy channel radius is The 0.1-0.3 of oxygen transferring in vein pipe radius.
7. the oxygen therapy method of a vein micro-nano mist oxygen device as claimed in claim 1, it is characterised in that comprise the following steps:
1), described oxygen transferring in vein pipe is inserted in vein blood vessel, and carries out the back works such as hemostasis sterilization;
2), set on described control panel and be passed through oxygen transferring in vein pipe oxygen pressure as a setting value;
3), described control panel transfer signals to controller, controller controls effusion meter and opens the most defeated in oxygen transferring in vein pipe Sending oxygen, the blood in vein blood vessel and the oxygen in oxygen transferring in vein pipe are at semipermeable membrane outer wall oxygenate, and piezometer monitoring simultaneously is quiet Oxygen pressure in arteries and veins oxygen catheter, keeps flow to be calculated as an opening angle when reaching setting value, during oxygenate, if there is pressure The oxygen pressure that power measures is higher than setting value, and signal is first fed back to controller by piezometer, and controller sends opens control valve life Making, control valve is opened an angle and makes the oxygen pressure in oxygen transferring in vein pipe gradually reduce, and when being reduced to setting value, controller is sent out Going out closing control valve order, if occurring, the oxygen pressure that piezometer records is less than setting value, and signal is fed back to controller by piezometer, Controller sends increase effusion meter opening angle order, until the oxygen pressure in oxygen transferring in vein pipe is equal to setting value;
4), during oxygenate, oxygen transferring in vein pipe inserts the blood inlet end blood oxygen concentration measuring instrument of vein blood vessel front and back end, hemorrhage end Oxygen content in forward and backward for the oxygenate recorded blood is fed back to controller and shows at chain of command by blood oxygen concentration measuring instrument respectively Plate, medical personnel revise the setting value of oxygen pressure in oxygen transferring in vein pipe accordingly.
CN201610764260.5A 2016-08-29 2016-08-29 A kind of vein micro-nano mist oxygen device and oxygen therapy method Active CN106237414B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109621052A (en) * 2019-01-31 2019-04-16 陈晓阳 A kind of intravascular oxygen supply system and oxygen supply method

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2166587Y (en) * 1993-03-21 1994-06-01 柴文淼 Honeycomb-like apparatus for aeration
CN1160529A (en) * 1997-01-30 1997-10-01 乔建民 Intracorporeal valve lung
CN1600381A (en) * 2004-10-21 2005-03-30 杜磊 Oxygenator inside vein
US20090093751A1 (en) * 2007-10-07 2009-04-09 Chi-Wei Tao Intravascular nano-bubbling oxygenator
CN206315324U (en) * 2016-08-29 2017-07-11 安徽通灵仿生科技有限公司 A kind of vein micro-nano mist oxygen device

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2166587Y (en) * 1993-03-21 1994-06-01 柴文淼 Honeycomb-like apparatus for aeration
CN1160529A (en) * 1997-01-30 1997-10-01 乔建民 Intracorporeal valve lung
CN1600381A (en) * 2004-10-21 2005-03-30 杜磊 Oxygenator inside vein
US20090093751A1 (en) * 2007-10-07 2009-04-09 Chi-Wei Tao Intravascular nano-bubbling oxygenator
CN206315324U (en) * 2016-08-29 2017-07-11 安徽通灵仿生科技有限公司 A kind of vein micro-nano mist oxygen device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109621052A (en) * 2019-01-31 2019-04-16 陈晓阳 A kind of intravascular oxygen supply system and oxygen supply method
CN109621052B (en) * 2019-01-31 2021-06-22 陈晓阳 Intravascular oxygen supply system and method

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