CN106237335A - A kind of dermatological field antibacterial - Google Patents
A kind of dermatological field antibacterial Download PDFInfo
- Publication number
- CN106237335A CN106237335A CN201610628172.2A CN201610628172A CN106237335A CN 106237335 A CN106237335 A CN 106237335A CN 201610628172 A CN201610628172 A CN 201610628172A CN 106237335 A CN106237335 A CN 106237335A
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- CN
- China
- Prior art keywords
- parts
- antibacterial
- surfactant
- alkylol
- dermatological field
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
- A01N43/42—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/40—Peroxides
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Environmental Sciences (AREA)
- Inorganic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The present invention relates to a kind of dermatological field antibacterial, including hydrogen peroxide, Carbostyril carboxylic acid derivatives, ethylenediaminetetraacetic acid compounds, alkylol, ether glycol, ammonium salt, surfactant, the mass fraction of each component is: hydrogen peroxide 25 parts, Carbostyril carboxylic acid derivatives 2 3.8 parts, ethylenediaminetetraacetic acid compounds 1.8 3 parts, alkylol 1.5 2.5 parts, ether glycol 2 2.5 parts, ammonium salt 2 2.5 parts, 1.5 3 parts of surfactant.This antibacterial has the advantage such as good stability, usage amount bacterium low, antibacterial spectrum wide, high-efficiency antimicrobial, antibacterial effect persistent period length, is widely used in various daily life field and medical domain.
Description
Technical field
The present invention relates to a kind of antibacterial.Especially, the present invention relates to a kind of antimicrobial, antibacterial, antifungal, antiviral
Dermatological field antibacterial.
Background technology
At present, clinical when treating various infective wound surface, the conventional treatments used is antibacterial, antiinflammatory, debridement.
External used medicine used over the course for the treatment of mostly is antibiosis anti-inflammatory drug.But there is certain weak point in these medicines.Such as clinic
The antibiotic medicines such as upper conventional tetracycline ointment, gentamycin sliver, nitrofural sliver, along with it is extensive and heavy dose of
Application, makes sensitive organism that it is produced corresponding Drug resistance, therefore unsatisfactory curative effect, adds antibiotics and only have antibacterial action,
The blood circulation of local organization and oozing out of suppression wound fluid can not be promoted, so, once there is Drug resistance in antibacterial, wound
The infection in face can deteriorate further, thus causes the disastrous effect of protracted course of disease.Though antibacterial is not likely to produce Drug resistance in the treatment, but
The effect of its antibacterial and anti-inflammation functions and promotion organization healing is the most weak, therefore the healing stage of wound is longer.Although natural prodcuts are pacified
Entirely, but typically expensive, broad-spectrum biological body such as Gram-negative and gram-positive bacterium and fungus are not had biocidal effect.
Summary of the invention
For above-mentioned deficiency present in prior art, the technical problem to be solved is to provide a kind of effective
Dermatological field antibacterial.
The technical solution adopted for the present invention to solve the technical problems is: provide a kind of dermatological field antibacterial,
Live including hydrogen peroxide, Carbostyril carboxylic acid derivatives, ethylenediaminetetraacetic acid compounds, alkylol, ether glycol, ammonium salt, surface
Property agent, the mass fraction of each component is: hydrogen peroxide 2-5 part, Carbostyril carboxylic acid derivatives 2-3.8 part, ethylenediaminetetraacetic acid class
Compound 1.8-3 part, alkylol 1.5-2.5 part, ether glycol 2-2.5 part, ammonium salt 2-2.5 part, surfactant 1.5-3 part.
As preferably, described dermatological field antibacterial, the mass fraction of each component is: hydrogen peroxide 2 parts, quinoline
Promise keto carboxylic acid derivatives 2 parts, ethylenediaminetetraacetic acid compounds 1.8 parts, alkylol 1.5 parts, ether glycol 2 parts, ammonium salt 2 parts, table
Face activating agent 1.5 parts.
As preferably, described dermatological field antibacterial, described surfactant is sulfonate, sulfate surface
Activating agent, phosphonate surfactant, phosphate surfactant active, pool network sand nurse, cationic surfactant or its mixing
Thing.
As preferably, described dermatological field antibacterial, alkylol, ether glycol are the reinforcing agent group of this antibacterial
Part,
The total concentration of enhancer component is relative to the total concentration of this antibacterial, by weight, in the range of 10:1 to 1:300.
As preferably, described dermatological field antibacterial, the total concentration of contained enhancer component is anti-relative to this
The total concentration of microbial inoculum, the most preferably in the range of 5:1 to 1:100.
This antibacterial has that good stability, usage amount bacterium low, antibacterial spectrum be wide, high-efficiency antimicrobial, the antibacterial effect persistent period
The advantages such as length, are widely used in various daily life field and medical domain.
Detailed description of the invention
A kind of dermatological field antibacterial that the present invention provides, including hydrogen peroxide, Carbostyril carboxylic acid derivatives, second
Ethylenediamine tetraacetic acid (EDTA) compounds, alkylol, ether glycol, ammonium salt, surfactant, the mass fraction of each component is: hydrogen peroxide
2-5 part, Carbostyril carboxylic acid derivatives 2-3.8 part, ethylenediaminetetraacetic acid compounds 1.8-3 part, alkylol 1.5-2.5 part, ether
Glycol 2-2.5 part, ammonium salt 2-2.5 part, surfactant 1.5-3 part.
As preferably, described dermatological field antibacterial, the mass fraction of each component is: hydrogen peroxide 2 parts, quinoline
Promise keto carboxylic acid derivatives 2 parts, ethylenediaminetetraacetic acid compounds 1.8 parts, alkylol 1.5 parts, ether glycol 2 parts, ammonium salt 2 parts, table
Face activating agent 1.5 parts.
As preferably, described dermatological field antibacterial, described surfactant is sulfonate, sulfate surface
Activating agent, phosphonate surfactant, phosphate surfactant active, pool network sand nurse, cationic surfactant or its mixing
Thing.
As preferably, described dermatological field antibacterial, alkylol, ether glycol are the reinforcing agent group of this antibacterial
Part,
The total concentration of enhancer component is relative to the total concentration of this antibacterial, by weight, in the range of 10:1 to 1:300.
As preferably, described dermatological field antibacterial, the total concentration of contained enhancer component is anti-relative to this
The total concentration of microbial inoculum, the most preferably in the range of 5:1 to 1:100.
The above, be only to presently preferred embodiments of the present invention, the present invention not do the restriction of other forms, appoints
What those skilled in the art changed possibly also with the technology contents of the disclosure above or be modified as changing on an equal basis etc.
Effect embodiment.Every without departing from the present invention program content, the technical spirit of the foundation present invention is to made for any of the above embodiments any
Simple modification, equivalent variations and remodeling, all fall within protection scope of the present invention.
Claims (5)
1. a dermatological field antibacterial, including hydrogen peroxide, Carbostyril carboxylic acid derivatives, ethylenediaminetetraacetic acid class
Compound, alkylol, ether glycol, ammonium salt, surfactant, the mass fraction of each component is: hydrogen peroxide 2-5 part, quinolinones carboxylic
Acid derivative 2-3.8 part, ethylenediaminetetraacetic acid compounds 1.8-3 part, alkylol 1.5-2.5 part, ether glycol 2-2.5 part, ammonium
Salt 2-2.5 part, surfactant 1.5-3 part.
Dermatological field antibacterial the most according to claim 1, the mass fraction of each component is: hydrogen peroxide 2 parts,
Carbostyril carboxylic acid derivatives 2 parts, ethylenediaminetetraacetic acid compounds 1.8 parts, alkylol 1.5 parts, ether glycol 2 parts, ammonium salt 2 parts,
1.5 parts of surfactant.
3., according to the dermatological field antibacterial described in claim 1-2, described surfactant is sulfonate, sulfate
Surfactant, phosphonate surfactant, phosphate surfactant active, pool network sand nurse, cationic surfactant or its mix
Compound.
Dermatological field antibacterial the most according to claim 1, alkylol, ether glycol are the reinforcing agent of this antibacterial
Component,
The total concentration of enhancer component is relative to the total concentration of this antibacterial, by weight, in the range of 10:1 to 1:300.
Dermatological field antibacterial the most according to claim 4, the total concentration of contained enhancer component is relative to this
The total concentration of antibacterial, the most preferably in the range of 5:1 to 1:100.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610628172.2A CN106237335A (en) | 2016-08-04 | 2016-08-04 | A kind of dermatological field antibacterial |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610628172.2A CN106237335A (en) | 2016-08-04 | 2016-08-04 | A kind of dermatological field antibacterial |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106237335A true CN106237335A (en) | 2016-12-21 |
Family
ID=57605952
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610628172.2A Pending CN106237335A (en) | 2016-08-04 | 2016-08-04 | A kind of dermatological field antibacterial |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106237335A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993015018A1 (en) * | 1992-01-24 | 1993-08-05 | John Petchul | Process and composition for microemulsion gel having bleaching and antiseptic properties |
| CN101048064A (en) * | 2004-09-07 | 2007-10-03 | 3M创新有限公司 | Antiseptic compositions and methods of use |
| CN101137343A (en) * | 2005-03-10 | 2008-03-05 | 3M创新有限公司 | Antimicrobial film-forming dental compositions and methods |
-
2016
- 2016-08-04 CN CN201610628172.2A patent/CN106237335A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993015018A1 (en) * | 1992-01-24 | 1993-08-05 | John Petchul | Process and composition for microemulsion gel having bleaching and antiseptic properties |
| CN101048064A (en) * | 2004-09-07 | 2007-10-03 | 3M创新有限公司 | Antiseptic compositions and methods of use |
| CN102908362A (en) * | 2004-09-07 | 2013-02-06 | 3M创新有限公司 | Antiseptic compositions and methods of use |
| CN101137343A (en) * | 2005-03-10 | 2008-03-05 | 3M创新有限公司 | Antimicrobial film-forming dental compositions and methods |
Non-Patent Citations (1)
| Title |
|---|
| 聂建军主编: "《药物化学》", 30 November 2015, 吉林大学出版社 * |
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Application publication date: 20161221 |