CN106236328A - A kind of novel porous titanium artificial hip joint - Google Patents

A kind of novel porous titanium artificial hip joint Download PDF

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Publication number
CN106236328A
CN106236328A CN201610757407.8A CN201610757407A CN106236328A CN 106236328 A CN106236328 A CN 106236328A CN 201610757407 A CN201610757407 A CN 201610757407A CN 106236328 A CN106236328 A CN 106236328A
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China
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porous titanium
cup
artificial hip
hip joint
novel
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CN201610757407.8A
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Chinese (zh)
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CN106236328B (en
Inventor
李瑞玲
金攻
涂江平
李众利
李玲玲
郭立
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ZHONGAO HUICHENG TECHNOLOGY Co.,Ltd.
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Middle Austria Converges Into Science And Technology Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/32—Joints for the hip
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0077—Special surfaces of prostheses, e.g. for improving ingrowth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/32—Joints for the hip
    • A61F2/34—Acetabular cups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A61L27/06—Titanium or titanium alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F3/00—Manufacture of workpieces or articles from metallic powder characterised by the manner of compacting or sintering; Apparatus specially adapted therefor ; Presses and furnaces
    • B22F3/10—Sintering only
    • B22F3/11—Making porous workpieces or articles
    • B22F3/1121—Making porous workpieces or articles by using decomposable, meltable or sublimatable fillers
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22C—ALLOYS
    • C22C14/00—Alloys based on titanium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00011—Metals or alloys
    • A61F2310/00023—Titanium or titanium-based alloys, e.g. Ti-Ni alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F2998/00—Supplementary information concerning processes or compositions relating to powder metallurgy
    • B22F2998/10—Processes characterised by the sequence of their steps

Abstract

The present invention relates to a kind of novel porous titanium artificial hip joint, it is less than the Ti6Al4V powder of 100 μm as raw material with particle diameter, a kind of aperture 400 1000 μm obtained by slurry injection moulding, vacuum-sintering, the porous titanium material of porosity 45 85%, can be as bionical bone implant material, the interface that solution bone implantation prosthese occurs due to metal material joint and host bone tissue loosens problem.With this porous titanium material as core, devise a kind of artificial hip joint with POROUS TITANIUM as surface, the artificial hip prosthesis on POROUS TITANIUM surface, is POROUS TITANIUM with host bone tissue contact interface, specifically includes and has the femoral stem of POROUS TITANIUM surface layer, POROUS TITANIUM acetabular cup.POROUS TITANIUM have promote mesenchymal cell to osteoid metaplasia, the effect that induced tissue generates, i.e. have bone formation in early days between interface, long-time stability in vivo after being effectively increased the early stage load of artificial hip prosthesis and implanting.

Description

A kind of novel porous titanium artificial hip joint
Technical field
The present invention relates to a kind of artificial hip prosthesis built with porous titanium material, specifically refer to utilize porous titanium material Construction features, improve the biological fixation effect between artificial hip prosthesis and host bone tissue, belong to new material in medical treatment The application in technique with the apparatus field.
Background technology
Interface cohesion between implant and host bone be maintain initial stage of implant and key steady in a long-term because of Element, increases the bone formation between bone-implant prosthese interface, makes artificial prosthesis and host bone form firm Integrated implant, thus can Reach near, fixing effect at a specified future date, reduces the generation of prosthetic loosening.At present, the joint that Replacement of Hip Joint uses is gold Belong to the joint of material, metal acetabulum cup, metal femoral stem and the fusion degree of host bone tissue, directly affect artificial hip joint false The load of body and long-time stability in vivo after implanting, and then affect the service life of artificial prosthesis.
Owing to organization structure of skeleton and metal structure exist larger difference, clinical practice has appreciated that this problem, mainly By hip joint acetabular outer cup and metal femoral stem surface spraying hydroxyapatite coating layer, titanium alloy powder, biological ceramic powder, The modes such as titanium pearl sintering, titanium silk sintering improve the roughness at artificial prosthesis interface.But clinical display: formed by said method Groove and rough surface are unsatisfactory to " Bone Ingrowth " effect in joint, exist low, easy with host's skeleton interface bond strength The problem of cracking, directly reduces the implantation life-span of articular prosthesis, and patient exists the potential risk of second operation.
In recent years, by the chemical deposition of titanium material or sintering, a kind of porous titanium material is developed.By changing POROUS TITANIUM Porosity, POROUS TITANIUM can be made to become, and a kind of to have good biocompatibility, biomechanics excellent, and elastic modelling quantity is close to bone The biomimetic material of tissue.Experiment display, the adjustment to POROUS TITANIUM pore structure, can reach and be replaced osseous tissue approximation The mechanical property joined, thus stress shielding is mitigated or eliminated, meanwhile, the structural adjustment of bionical thing transport channel, can be by connection Three-dimensional porous structure make moisture and nutrient substance in implant internal transmission, promote that bone tissue in-growth is formed biological solid Fixed, reach the function that artificial prosthesis merges with host bone tissue, thus strengthen between implantable artificial prosthese and host bone tissue Interface stability, therefore, using POROUS TITANIUM as artificial hip joint Bone Ingrowth active interface, implants prosthetic arts at bone and has greatly Value for clinical application, can further improve the service life of artificial joint.
Summary of the invention
The present invention provides a kind of porous titanium material, using this porous titanium material as artificial hip joint and body-contacting surface, Form a kind of artificial hip prosthesis.Specifically refer at the prosthese mortar cup contacted with host bone tissue, femoral stem surface construction many Titanium surface, hole, utilizes the bone trabecular three-dimensional connected porous structure of its class, promotes mesenchymal cell to osteoid metaplasia, induces host Osseous tissue generate, solve artificial hip prosthesis Bone Ingrowth effect pay no attention to think of artificial prosthesis implant the stability in later stage, peace Full property and the problem such as service life is the highest.
The technic relization scheme that the present invention relates to is: the first, invent a kind of POROUS TITANIUM with three-dimensional connected porous structure Material, this material has and is similar to the little beam structure of human bone, and all ducts all can guarantee that and are interconnected, it is ensured that body bone tissue It is fully grown into；The second, a kind of artificial hip joint is designed with this porous titanium material.
The specific scheme is that
A kind of novel porous titanium artificial hip joint, including femoral stem, femur bulb, acetabular bone liner and POROUS TITANIUM acetabular cup；
Artificial hip prosthesis and host bone tissue contact surface are POROUS TITANIUM material, specifically include and have POROUS TITANIUM surface The femoral stem of layer, POROUS TITANIUM acetabular cup；
Described femoral stem includes POROUS TITANIUM oversleeve and metal shank body, and described POROUS TITANIUM oversleeve and described metal shank body are by swashing The mode of light spot welding connects；
Described POROUS TITANIUM acetabular cup is by POROUS TITANIUM cup and is arranged at the metal cup of described POROUS TITANIUM cup inner surface and forms；Or Described POROUS TITANIUM acetabular cup is only made up of described POROUS TITANIUM cup.
Described POROUS TITANIUM, for having three-dimensional connected porous structure, is similar to human bone girder sample, and keeps being completely in Connected state, plays bone trabecula effect, it is ensured that body bone tissue is fully grown into.
Described POROUS TITANIUM oversleeve is that one-shaping technique obtains, and is arranged at the outer surface of described metal shank body, with metal handle Body uses laser welding technology to combine.
Described metal shank body and described POROUS TITANIUM oversleeve contact site are provided with thread-like structure.
Described POROUS TITANIUM acetabular cup inner surface uses paint-on technique to process, and one-shot forming strengthens POROUS TITANIUM consistency, improves Comprcssive strength.
Described POROUS TITANIUM is prepared less than the Ti6Al4V powder of 100 μm by particle diameter, and weight percentage is described In Ti6Al4V powder, C element content is less than 1.0wt% less than 0.08wt%, O constituent content, N element content is less than 0.5wt%, Fe constituent content is less than 0.15wt% less than 0.3wt%, Si constituent content；Described POROUS TITANIUM aperture is 400-1000 μm, hole Rate 45-85%.
Described POROUS TITANIUM is that one is mixed into uniform sizing material, injection moulding, height by Ti6Al4V powder and gelatin forming agent In temperature vacuum, sintering makes aperture 400-1000 μm, the porous titanium material of porosity 45-85%；The bullet of described POROUS TITANIUM surface layer Property modulus 1000-4000MPa, comprcssive strength 50-120MPa.
Described POROUS TITANIUM sintering process at least keeps vacuum 10-2Below mbar is carried out, and at the uniform velocity heats up, and temperature range is protected Hold between 700-1200 DEG C.
Described POROUS TITANIUM oversleeve thickness is 1-4.5mm.
The outer surface of described metal cup is provided with meshed grooves；Described meshed grooves is provided with POROUS TITANIUM cup；Described POROUS TITANIUM cup uses pulsed laser welding to be combined with the metal cup of its inner surface；
When described POROUS TITANIUM acetabular cup is made up of described POROUS TITANIUM cup and described metal cup, described metal cup thickness is 1- 2.0mm；
When described POROUS TITANIUM acetabular cup is only made up of described POROUS TITANIUM cup, described POROUS TITANIUM cup thickness is 3.0-5.5mm.
In described metal handle body, platform has been built with the contact site of described host bone tissue in side, and described platform is placed in described In host bone tissue, prevent described metal shank body from sinking.
The invention has the beneficial effects as follows:
The POROUS TITANIUM of the present invention has good biocompatibility, aperture, porosity, elastic modelling quantity and host bone tissue phase Seemingly；The infiltration response of POROUS TITANIUM surface layer structure simultaneously, beneficially in blood, composition carries out the functionalization synthesis of bone-imitation tissue；Closely Being similar to the POROUS TITANIUM of human bone girder sample, all ducts all can guarantee that and are interconnected, and can induce osseous tissue early origin, improve Early stage load capacity after Using prosthesis.POROUS TITANIUM acetabular cup, particularly full POROUS TITANIUM acetabular cup and POROUS TITANIUM oversleeve, compensate for existing Having the deficiency spraying the mode such as hydroxyapatite, titanium alloy powder at acetabular outer cup and metal femoral stem surface, body bone tissue is complete After total length enters, the POROUS TITANIUM oversleeve of adequate thickness and full POROUS TITANIUM acetabular cup, can guarantee that the knot that prosthese is enough with host bone interface Close intensity, be effectively increased artificial hip joint long-time stability in vivo, make artificial hip prosthesis real with host bone tissue Existing depth integration.
Accompanying drawing explanation
Fig. 1 is the structural representation of POROUS TITANIUM；
Fig. 2 is POROUS TITANIUM elastic modelling quantity test curve figure；
Fig. 3 is the partial enlarged drawing of Fig. 1；
Fig. 4 is POROUS TITANIUM surface artificial hip prosthesis structural representation；
Fig. 5 is an embodiment schematic diagram of POROUS TITANIUM acetabular cup；
Fig. 6 is another embodiment schematic diagram of POROUS TITANIUM acetabular cup；
Fig. 7 is femoral stem structural representation；
Fig. 8 is POROUS TITANIUM Using prosthesis dog body 6 weeks, and bone compares figure with the combination of POROUS TITANIUM.
Description of reference numerals
1 POROUS TITANIUM acetabular cup, 2 acetabular bone liners, 3 femur bulbs, 4 femoral stem, 11 POROUS TITANIUM cups, 12 metal cups, 101 porous Titanium cup, 41 metal shank body, 42 POROUS TITANIUM oversleeves, 411 platforms.
Detailed description of the invention
Describing technical scheme by the following examples in detail, below example is only exemplary, only Can be used for explaining and illustrate technical scheme, and be not to be construed as the restriction to technical solution of the present invention.
Embodiment 1
A kind of artificial hip joint with porous titanium material as articular surface, as shown in Fig. 1 to 4 and Fig. 6 to Fig. 8, including tool Having the femoral stem 4 of POROUS TITANIUM surface layer, femur bulb 3, acetabular bone liner 2 and POROUS TITANIUM acetabular cup 1, porous titanium material builds at hip Mortar cup, the surface of femoral stem；In this application, acetabular bone liner is polyethylene liner.
In the application Fig. 8, Ti is POROUS TITANIUM；B is dog femora cancellous bone.
POROUS TITANIUM uses the Ti6Al4V powder of 0-45 μm and gelatin forming agent to be mixed into uniform sizing material, and injection moulding, at height Temperature vacuum sinters and forms.Weight percentage is calculated, and in Ti6Al4V powder, C element content is that 0.05wt%, O element contains Amount is 0.8wt%, and N element content is 0.2wt%, and Fe constituent content is 0.03wt%, and Si constituent content is less than 0.018wt%. POROUS TITANIUM average pore size 650 μm, porosity 75%, elastic modelling quantity 3300MPa, comprcssive strength about 53MPa, POROUS TITANIUM is for having bone The pore structure of girder sample three-dimensional communication.POROUS TITANIUM sintering process keeps vacuum 10-2Carrying out under mbar, remain a constant speed liter Temperature, until temperature arrives 1100 DEG C.
Femoral stem 4 includes POROUS TITANIUM oversleeve 42 and metal shank body 41, and POROUS TITANIUM oversleeve 42 one-shot forming obtains, and is arranged at gold Belonging to shank body 41 outer surface, use pulsed laser welding to be combined with metal shank body 41, POROUS TITANIUM oversleeve 42 thickness is 3mm.
POROUS TITANIUM acetabular cup 1 is all made up of POROUS TITANIUM cup 101, and inner surface uses paint-on technique to process, and thickness is 4.0mm。
Metal shank body 41 and POROUS TITANIUM oversleeve 42 connecting part are provided with thread-like structure, metal shank body 41 and host bone group Knit and inside contact site, built platform 411, be placed in host bone tissue.Host bone tissue is existed by POROUS TITANIUM postadhesion of growing into On the helicitic texture of metal shank body, improving stationarity to maintain the initial and long-term stability of femoral stem, platform 411 can prevent gold Belong to shank body 41 to sink.
Embodiment 2
A kind of POROUS TITANIUM is the artificial hip joint of articular surface, as shown in Fig. 1 to Fig. 5 and Fig. 7 and Fig. 8, many including having The femoral stem 4 of hole titanium surface layer, femur bulb 3, acetabular bone liner 2 and POROUS TITANIUM acetabular cup 1, porous titanium material builds at acetabular cup And femoral stem surface；In this application, acetabular bone liner is polyethylene liner.
POROUS TITANIUM uses Ti6Al4V powder and the gelatin forming agent of 15-53 μm to be mixed into uniform sizing material, injection moulding, In high-temperature vacuum, sintering forms.Weight percentage is calculated, and in Ti6Al4V powder, C element content is 0.011wt%, O element Content is 0.12wt%, N element content be 0.013wt%, Fe constituent content be that 0.2wt%, Si constituent content is less than 0.035wt%.POROUS TITANIUM average pore size 500 μm, porosity 80%, elastic modelling quantity 3500MPa, comprcssive strength about 60MPa, porous Titanium is the pore structure with the spongy three-dimensional communication of bone trabecula sample.
POROUS TITANIUM sintering process keeps vacuum 10-2Carrying out under mbar, remain a constant speed intensification, until temperature arrives 1100 ℃。
Femoral stem 4 includes POROUS TITANIUM oversleeve 42 and metal shank body 41, and POROUS TITANIUM oversleeve 42 one-shot forming obtains, and is arranged at gold Belonging to shank body 41 outer surface, use pulsed laser welding to be combined with metal shank body 41, POROUS TITANIUM oversleeve 42 thickness is 3mm.
POROUS TITANIUM acetabular cup is by POROUS TITANIUM cup 11 and is arranged at its internal metal cup 12 and forms.
The outer surface of metal cup 12 is provided with meshed grooves, and thickness is 2.0mm；Meshed grooves is provided with POROUS TITANIUM cup 11, POROUS TITANIUM cup 11 thickness is 2.0mm, and inner surface uses paint-on technique to process.
Metal shank body 41 and POROUS TITANIUM oversleeve 42 connecting part are provided with thread-like structure, metal shank body 41 and host bone group Knit and inside contact site, built platform 411, host bone tissue by POROUS TITANIUM grow into postadhesion metal shank body screw thread tie On structure, improving stationarity to maintain the initial and long-term stability of femoral stem, platform 411 can prevent metal shank body 41 from sinking.
The artificial hip joint that the present embodiment provides implants prosthese, includes POROUS TITANIUM acetabular cup and POROUS TITANIUM oversleeve surface layer Joint femoral stem, and with the femur bulb of its compatibility and acetabular bone liner, after this Using prosthesis human body, osteocyte can be grown into many Hole titanium layer is the hole of bone trabecula sample three-dimensional communication, increases the amalgamation with body bone tissue, is effectively increased artificial hip joint The early stage load of prosthese and long-time stability in vivo after implanting.
Although being described in detail technical scheme, but those skilled in the art is the most clear Chu, by the amendment carrying out the technical program, replaces and modification etc., all should be within the protection domain of the application.

Claims (11)

1. a novel porous titanium artificial hip joint, including femoral stem, femur bulb, acetabular bone liner and POROUS TITANIUM acetabular cup；Its It is characterised by:
Artificial hip prosthesis and host bone tissue contact surface are POROUS TITANIUM material, specifically include and have POROUS TITANIUM surface layer Femoral stem, POROUS TITANIUM acetabular cup；
Described femoral stem includes that POROUS TITANIUM oversleeve and metal shank body, described POROUS TITANIUM oversleeve and described metal shank body pass through laser spots The mode of weldering connects；
Described POROUS TITANIUM acetabular cup is by POROUS TITANIUM cup and is arranged at the metal cup of described POROUS TITANIUM cup inner surface and forms；Or it is described POROUS TITANIUM acetabular cup is only made up of described POROUS TITANIUM cup.
Novel porous titanium artificial hip joint the most according to claim 1, it is characterised in that: described POROUS TITANIUM is for having three-dimensional Connected porous structure, is similar to human bone girder sample, and keeps being completely in connected state, play bone trabecula effect, it is ensured that Body bone tissue is fully grown into.
Novel porous titanium artificial hip joint the most according to claim 1, it is characterised in that: described POROUS TITANIUM oversleeve is once Forming technique obtains, and is arranged at the outer surface of described metal shank body, uses laser welding technology to be combined with metal shank body.
Novel porous titanium artificial hip joint the most according to claim 3, it is characterised in that: described metal shank body is with described many Titanium oversleeve contact site, hole is provided with thread-like structure.
Novel porous titanium artificial hip joint the most according to claim 1, it is characterised in that: table in described POROUS TITANIUM acetabular cup Face uses paint-on technique to process, and one-shot forming strengthens POROUS TITANIUM consistency, improves comprcssive strength.
Novel porous titanium artificial hip joint the most according to claim 1, it is characterised in that: described POROUS TITANIUM is less than by particle diameter Prepared by the Ti6Al4V powder of 100 μm, weight percentage, and in described Ti6Al4V powder, C element content is less than 0.08wt%, O constituent content is first less than 0.3wt%, Si less than 0.5wt%, Fe constituent content less than 1.0wt%, N element content Cellulose content is less than 0.15wt%；Described POROUS TITANIUM aperture is 400-1000 μm, porosity 45-85%.
Novel porous titanium artificial hip joint the most according to claim 6, it is characterised in that: described POROUS TITANIUM is that one is passed through Ti6Al4V powder and gelatin forming agent are mixed into uniform sizing material, injection moulding, and in high-temperature vacuum, sintering makes aperture 400-1000 μm, the porous titanium material of porosity 45-85%；The elastic modelling quantity 1000-4000MPa of described POROUS TITANIUM surface layer, comprcssive strength 50-120MPa。
Novel porous titanium artificial hip joint the most according to claim 7, it is characterised in that: described POROUS TITANIUM sintering process is extremely Keep vacuum 10 less-2Below mbar is carried out, and at the uniform velocity heats up, and temperature range is maintained between 700-1200 DEG C.
Novel porous titanium artificial hip joint the most according to claim 1, it is characterised in that: described POROUS TITANIUM oversleeve thickness is 1-4.5mm。
Novel porous titanium artificial hip joint the most according to claim 1, it is characterised in that: the outer surface of described metal cup It is provided with meshed grooves；Described meshed grooves is provided with POROUS TITANIUM cup；Described POROUS TITANIUM cup and the metal cup of its inner surface Employing pulsed laser welding combines；
When described POROUS TITANIUM acetabular cup is made up of described POROUS TITANIUM cup and described metal cup, described metal cup thickness is 1- 2.0mm；
When described POROUS TITANIUM acetabular cup is only made up of described POROUS TITANIUM cup, described POROUS TITANIUM cup thickness is 3.0-5.5mm.
11. novel porous titanium artificial hip joints according to claim 1, it is characterised in that: in described metal handle body side with Platform has been built in the contact site of described host bone tissue, and described platform is placed in described host bone tissue, prevents described metal Shank body is sunk.
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CN108042243A (en) * 2018-01-17 2018-05-18 上海科太迈迪医疗器械有限公司 Integral acetabular component of cup lining and preparation method thereof
WO2019113886A1 (en) * 2017-12-14 2019-06-20 中奥汇成科技股份有限公司 Novel bionic titanium artificial joint prosthesis
CN111281610A (en) * 2019-12-30 2020-06-16 雅博尼西医疗科技(苏州)有限公司 Connection structure of porous structure and substrate
CN111297519A (en) * 2020-02-17 2020-06-19 赵德伟 Metal hip joint prosthesis with porous layer structure and preparation method thereof
WO2022088701A1 (en) * 2020-10-30 2022-05-05 嘉思特华剑医疗器材(天津)有限公司 Zirconium niobium alloy hip joint prosthesis system comprising oxide layer, and preparation method therefor
JP2022542020A (en) * 2019-07-19 2022-09-29 インテグリス・インコーポレーテッド Porous sintered membrane and method of preparing porous sintered membrane
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CN117399774A (en) * 2023-12-12 2024-01-16 北京市春立正达医疗器械股份有限公司 CVD hip joint vacuum diffusion welding prosthesis manufacturing method and hip joint prosthesis

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WO2019113886A1 (en) * 2017-12-14 2019-06-20 中奥汇成科技股份有限公司 Novel bionic titanium artificial joint prosthesis
CN108042243A (en) * 2018-01-17 2018-05-18 上海科太迈迪医疗器械有限公司 Integral acetabular component of cup lining and preparation method thereof
JP2022542020A (en) * 2019-07-19 2022-09-29 インテグリス・インコーポレーテッド Porous sintered membrane and method of preparing porous sintered membrane
CN111281610B (en) * 2019-12-30 2023-08-18 雅博尼西医疗科技(苏州)有限公司 Porous structure and connection structure of substrate
CN111281610A (en) * 2019-12-30 2020-06-16 雅博尼西医疗科技(苏州)有限公司 Connection structure of porous structure and substrate
CN111297519B (en) * 2020-02-17 2021-05-25 赵德伟 Metal hip joint prosthesis with porous layer structure and preparation method thereof
CN111297519A (en) * 2020-02-17 2020-06-19 赵德伟 Metal hip joint prosthesis with porous layer structure and preparation method thereof
WO2022088701A1 (en) * 2020-10-30 2022-05-05 嘉思特华剑医疗器材(天津)有限公司 Zirconium niobium alloy hip joint prosthesis system comprising oxide layer, and preparation method therefor
JP7470194B2 (en) 2020-10-30 2024-04-17 嘉思特医療器材（天津）股▲ふん▼有限公司 Zirconium-niobium alloy hip joint prosthesis system containing an oxide layer and method of manufacture thereof
CN116172759A (en) * 2023-04-24 2023-05-30 北京纳通医疗科技控股有限公司 Acetabular cup
CN116172759B (en) * 2023-04-24 2023-08-04 北京纳通医疗科技控股有限公司 Acetabular cup
CN117399774A (en) * 2023-12-12 2024-01-16 北京市春立正达医疗器械股份有限公司 CVD hip joint vacuum diffusion welding prosthesis manufacturing method and hip joint prosthesis
CN117399774B (en) * 2023-12-12 2024-04-16 北京市春立正达医疗器械股份有限公司 CVD hip joint vacuum diffusion welding prosthesis manufacturing method and hip joint prosthesis

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