CN106212519A - Herba nepenthis extract mosquito incense liquid and preparation method thereof - Google Patents
Herba nepenthis extract mosquito incense liquid and preparation method thereof Download PDFInfo
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- CN106212519A CN106212519A CN201610654814.6A CN201610654814A CN106212519A CN 106212519 A CN106212519 A CN 106212519A CN 201610654814 A CN201610654814 A CN 201610654814A CN 106212519 A CN106212519 A CN 106212519A
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/18—Vapour or smoke emitting compositions with delayed or sustained release
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/02—Acyclic compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/22—Lamiaceae or Labiatae [Mint family], e.g. thyme, rosemary, skullcap, selfheal, lavender, perilla, pennyroyal, peppermint or spearmint
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The invention belongs to mosquito incense field, be specifically related to Herba nepenthis extract mosquito incense liquid and preparation method thereof.It is made up according to the raw material of weight portion of following: Herba nepenthis extracting solution 110 160 parts, Folium Artemisiae Argyi extracting solution 67 94 parts, fly expelling plum extracting solution 33 51 parts, lavandula angustifolia extracting solution 8 20 parts, deionized water 40 60 parts and ethanol 30 55 parts.During preparation, Herba nepenthis extracting solution, Folium Artemisiae Argyi extracting solution, fly expelling plum extracting solution, lavandula angustifolia extracting solution is prepared respectively through ultrasonic, centrifugal, concentration etc., again Herba nepenthis extracting solution, Folium Artemisiae Argyi extracting solution, fly expelling plum extracting solution, lavandula angustifolia extracting solution, deionized water and ethanol are mixed, stir 3 6h at 53 70 DEG C of lower seals, obtain Herba nepenthis extract mosquito incense liquid.The effective ingredient of the present invention is extracted by natural Chinese medicinal herb and obtain, and cost is relatively low, and prepared product safety is nontoxic, has sterilization, anophelifuge, effect of helping for sleep.
Description
Technical field
The invention belongs to mosquito incense field, be specifically related to Herba nepenthis extract mosquito incense liquid and preparation method thereof.
Background technology
In south, the spring and summer autumn all can have mosquito to haunt, and summer is mosquito activity period the most frequently, lives in south
People often bitten by mosquito, the sound of that " drone drone ", also have that to inhale the mosquito just sworn not to stop less than blood, always
Be to allow people cannot sleep what a sound sleep, allow people be pestered beyond endurance, serious orthobiosis that have impact on people, work, learn and
Having a rest, more seriously, biting of mosquito also can propagate various disease, and healthy to people brings serious prestige
The side of body；And mosquito incense is as a kind of anophelifuge articles for use, flying into common people house already, wherein the use of mosquito liquid is also the most general
Time, but the face that mosquito liquid involves is relatively wider, and the factor of impact is the most, so will be to developing a kind of cost performance height, becoming
The non-easy thing of ripe product.The mosquito liquid of existing market, its effective ingredient is along with mosquito is to which creating certain Drug resistance
Afterwards, it has to strengthening they consumptions in mosquito liquid, the cost causing mosquito liquid is higher, furthermore strengthen
After its effective ingredient the most toxic, life-time service is unfavorable to health.
Summary of the invention
The goal of the invention of the present invention is: for the deficiency of above-mentioned existence, the invention provides Herba nepenthis extract mosquito incense
Liquid, its effective ingredient is extracted by natural Chinese medicinal herb and obtains, and cost is relatively low, and the product safety prepared is nontoxic, has sterilization, drives
Mosquito, the effect helped for sleep.
To achieve these goals, the technical solution used in the present invention is as follows:
A kind of Herba nepenthis extract mosquito incense liquid, is made up of the medicine of following weight portion: Herba nepenthis extracting solution 110-160 part, Folium Artemisiae Argyi
Extracting solution 67-94 part, fly expelling plum extracting solution 33-51 part, lavandula angustifolia extracting solution 8-20 part, deionized water 40-60 part and ethanol 30-
55 parts.
Further, described Herba nepenthis extract mosquito incense liquid, it is made up of the medicine of following weight portion: Herba nepenthis extracting solution
120-150 part, Folium Artemisiae Argyi extracting solution 76-85 part, fly expelling plum extracting solution 39-45 part, lavandula angustifolia extracting solution 12-16 part, deionized water
45-55 part and ethanol 35-50 part.
Further, described Herba nepenthis extract mosquito incense liquid, it is made up of the medicine of following weight portion: Herba nepenthis extracting solution
135 parts, Folium Artemisiae Argyi extracting solution 79 parts, fly expelling plum extracting solution 42 parts, lavandula angustifolia extracting solution 14 parts, deionized water 50 parts and ethanol 46
Part.
Further, the preparation method of described Herba nepenthis extract mosquito incense liquid, comprise the steps of:
(1) Herba nepenthis extracting solution: after Herba nepenthis roguing, drying, is cut into the segment of 2-6cm, sends in super micron mill and pulverizes
Becoming powder, the ethanol of 11-15 times of quality of addition refluxes at 50-65 DEG C and extracts 10-15h, filtrate is collected by filtration, and extracting solution is dense
It is condensed to 1/10th of original solution volume, obtains Herba nepenthis extracting solution；
(2) Folium Artemisiae Argyi extracting solution: by Folium Artemisiae Argyi roguing, dry after send in super micron mill and be ground into powder, in 9-13 times of matter of Folium Artemisiae Argyi
The ethanol of amount seals and soaks 2-4h, be then sonicated 35-45min and obtain Folium Artemisiae Argyi solution, then collect centrifuged supernatant the most afterwards,
It is concentrated into 1/10th of liquor capacity with Rotary Evaporators, obtains Folium Artemisiae Argyi extracting solution；
(3) fly expelling plum extracting solution: by fly expelling plum roguing, dry after send in super micron mill and be ground into powder, at fly expelling plum 7-
The ethanol of 12 times of quality seals and soaks 5-8h, be then sonicated 30-40min and obtain Folium Artemisiae Argyi solution, then collect centrifugal the most afterwards
Supernatant；Gained precipitate adds the ethanol of its quality 5-9 times and carries out twice ultrasonic extraction, and supersound process 30-40min must be by
Fly prunus mume (sieb.) sieb.et zucc. solution, then collect centrifuged supernatant the most afterwards；Merge two times centrifugal supernatant, and be concentrated into solution with Rotary Evaporators
/ 10th of volume, obtain fly expelling plum extracting solution；
(4) lavandula angustifolia extracting solution: add the ethanol of 6-11 times of quality of lavandula angustifolia, reflux, extract, 3-6h at 70-90 DEG C, be cooled to
After less than 40 DEG C, natural filtration removes residue, retells weight and is concentrated into 1/10th, i.e. obtains lavandula angustifolia extracting solution；
(5) by the Herba nepenthis extracting solution of step (1), the Folium Artemisiae Argyi extracting solution of step (2), the fly expelling plum extracting solution of step (3), step
(4) lavandula angustifolia extracting solution, deionized water and ethanol mixing, stirs 3-6h at 53-70 DEG C of lower seal, i.e. obtains Herba nepenthis and extract
Thing mosquito incense liquid.
Further, the preparation method of described Herba nepenthis extract mosquito incense liquid, in step (1), the mesh of described powder
Granularity is 300-500 mesh, and described filtering technique is natural filtration, and described concentration technology is concentrating under reduced pressure.
Further, the preparation method of described Herba nepenthis extract mosquito incense liquid, in step (2) and step (3), described
The mesh granularity of powder is 150-250 mesh, and the temperature of described ethanol is 35-45 DEG C.
Further, the preparation method of described Herba nepenthis extract mosquito incense liquid, in step (5), described stirring technique
Mixing speed be 200-300r/min.
Effect of each component used in the present invention is as follows:
Herba nepenthis: Classification system: Nepenthes sp, have another name called water pot plant, monkey water bottle, the monkey field of razor clam, zhuzailong, Thunder God kettle, property
Cold, puckery, there is effect of clearing away lung-heat and moistening for dryness, Hang Shui, removing toxic substances." Luchuan book on Chinese herbal medicine ": " cold in nature, puckery." " Luchuan book on Chinese herbal medicine ": " antiinflammatory,
Removing toxic substances, row water.Harnessing the river swollen, dysentery, carbuncle sore ulcer is red and swollen, and insect bite is hindered, and controls traumatic injury.”
Folium Artemisiae Argyi: Classification system: Artemisia argyi H. L é v. Vaniot, another name Xiao Mao, ice platform, holds back grass, Artemisia argyi, begs
Chinese mugwort, Ai Xiao, Radix Artemisia ordosicae, Radix Artemisia ordosicae, fluffy ligusticumic, moxa-moxibustion herbalist's straw colour grass Folium Artemisiae Argyi etc., nature and flavor are bitter, pungent, warm, enter spleen, liver, kidney, herb
Be used as medicine, have warming the meridian, dry, cold expelling, hemostasis, antiinflammatory, relieving asthma, cough-relieving, the effect such as antiabortive, antiallergic." herbal " is recorded: Folium Artemisiae Argyi property
Bitter in the mouth is pungent, warm, preferably supports spleen, liver, kidney.Folium Artemisiae Argyi Chinese mugwort stalk, decapacitation is enough brewed into outside the decoction got rid of illness, when the traditional Chinese medical science implements acupuncture,
Also often it is bonded to backshank kneading pockets of Folium Artemisiae Argyi, after lighting, is used as auxiliary treatment.
Fly expelling plum: Classification system: Lantana camara L, another name Folium Lantanae Camarae, Herba rutae, smelly gold phoenix, variable color nose careless, continuous public affairs
Flower, has effect of anophelifuge.
Lavandula angustifolia: Classification system: Lavandula angustifolia Mill, have another name called perfume plant, Herba Lysimachiae foenum-graeci, Rhizoma et radix valerianae,
Colophonium grass.There is pharmacologically active, tranquilizing soporific, spasmolytic, antibacterial, the effect of neuroprotective.
In sum, due to the fact that and have employed such scheme, the present invention has the positive effect that:
The natural plant each component of mosquito incense liquid of the present invention is taken from the Nature, and raw material is simple and easy to get, low cost, manufacture method letter
Single, easily operate, price is the most preferential, is suitable for commercial production.The abnormal smells from the patient distributed during the heating volatilization of mosquito incense liquid is not only
The viral pathogenic bacteria in air, expelling mosquito can be killed, it is also possible to the effect effectively helped for sleep.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is purged, is fully described by,
Obviously, described embodiment is only a part of embodiment of the present invention rather than whole embodiments.Based in the present invention
Embodiment, the every other embodiment that those of ordinary skill in the art are obtained under not making creative work premise, all
Belong to the scope of protection of the invention.
Embodiment 1
A kind of Herba nepenthis extract mosquito incense liquid, is made up of the medicine of following weight portion:
Herba nepenthis extracting solution 110 parts, Folium Artemisiae Argyi extracting solution 67 parts, fly expelling plum extracting solution 33 parts, lavandula angustifolia extracting solution 8 parts, deionization
40 parts of water and ethanol 30 parts.
The preparation method of above-mentioned Herba nepenthis extract mosquito incense liquid, comprises the steps of:
(1) Herba nepenthis extracting solution: after Herba nepenthis roguing, drying, is cut into the segment of 2cm, sends in super micron mill and is ground into
Mesh granularity is the powder of 300 mesh, and the ethanol of 11 times of quality of addition refluxes at 50 DEG C and extracts 10h, and natural filtration collects filtrate, will
Extracting solution concentrating under reduced pressure is 1/10th of original solution volume, obtains Herba nepenthis extracting solution；
(2) Folium Artemisiae Argyi extracting solution: by Folium Artemisiae Argyi roguing, dry after send in super micron mill and be ground into the powder that mesh granularity is 150 mesh,
Sealing in the ethanol of 9 times of quality of Folium Artemisiae Argyi and soak 2h, the temperature of ethanol is 35 DEG C, is then sonicated 35min and obtains Folium Artemisiae Argyi solution, then
Collect centrifuged supernatant the most afterwards, be concentrated into 1/10th of liquor capacity with Rotary Evaporators, obtain Folium Artemisiae Argyi extracting solution；
(3) fly expelling plum extracting solution: by fly expelling plum roguing, dry after send in super micron mill that to be ground into mesh granularity be 150 purposes
Powder, seals in the ethanol of 7 times of quality of fly expelling plum and soaks 5h, and the temperature of ethanol is 35 DEG C, is then sonicated 30min and obtains Folium Artemisiae Argyi
Solution, then collect centrifuged supernatant the most afterwards；Gained precipitate adds the ethanol of its quality 5 times to carry out twice ultrasonic and carries
Taking, supersound process 30min obtains fly expelling plum solution, then collects centrifuged supernatant the most afterwards；Merge two times centrifugal supernatant, and use
Rotary Evaporators is concentrated into 1/10th of liquor capacity, obtains fly expelling plum extracting solution；
(4) lavandula angustifolia extracting solution: add the ethanol of 6 times of quality of lavandula angustifolia, reflux, extract, 3h at 70 DEG C, be cooled to less than 40 DEG C
After, natural filtration removes residue, then weight Rotary Evaporators is concentrated into 1/10th, i.e. obtains lavandula angustifolia extracting solution；
(5) by the Herba nepenthis extracting solution of step (1), the Folium Artemisiae Argyi extracting solution of step (2), the fly expelling plum extracting solution of step (3), step
(4) lavandula angustifolia extracting solution, deionized water and ethanol mixing, the speed lower seal at 53 DEG C, 200r/min stirs 3h, i.e. obtains
Herba nepenthis extract mosquito incense liquid.
Embodiment 2
A kind of Herba nepenthis extract mosquito incense liquid, is made up of the medicine of following weight portion:
Herba nepenthis extracting solution 160 parts, Folium Artemisiae Argyi extracting solution 94 parts, fly expelling plum extracting solution 51 parts, lavandula angustifolia extracting solution 20 parts, deionization
60 parts of water and ethanol 55 parts.
The preparation method of above-mentioned Herba nepenthis extract mosquito incense liquid, comprises the steps of:
(1) Herba nepenthis extracting solution: after Herba nepenthis roguing, drying, is cut into the segment of 6cm, sends in super micron mill and is ground into
Mesh granularity is the powder of 500 mesh, and the ethanol of 15 times of quality of addition refluxes at 65 DEG C and extracts 15h, and natural filtration collects filtrate, will
Extracting solution concentrating under reduced pressure is 1/10th of original solution volume, obtains Herba nepenthis extracting solution；
(2) Folium Artemisiae Argyi extracting solution: by Folium Artemisiae Argyi roguing, dry after send in super micron mill and be ground into the powder that mesh granularity is 250 mesh,
Sealing in the ethanol of 13 times of quality of Folium Artemisiae Argyi and soak 4h, the temperature of ethanol is 45 DEG C, is then sonicated 45min and obtains Folium Artemisiae Argyi solution,
Collect centrifuged supernatant the most afterwards, be concentrated into 1/10th of liquor capacity with Rotary Evaporators, obtain Folium Artemisiae Argyi extracting solution；
(3) fly expelling plum extracting solution: by fly expelling plum roguing, dry after send in super micron mill that to be ground into mesh granularity be 250 purposes
Powder, seals in the ethanol of 12 times of quality of fly expelling plum and soaks 8h, and the temperature of ethanol is 45 DEG C, and being then sonicated 40min must end
Grass solution, then collect centrifuged supernatant the most afterwards；Gained precipitate adds the ethanol of its quality 9 times to carry out twice ultrasonic and carries
Taking, supersound process 40min obtains fly expelling plum solution, then collects centrifuged supernatant the most afterwards；Merge two times centrifugal supernatant, and use
Rotary Evaporators is concentrated into 1/10th of liquor capacity, obtains fly expelling plum extracting solution；
(4) lavandula angustifolia extracting solution: add 11 times of quality of lavandula angustifolia ethanol, reflux, extract, 6h at 90 DEG C, be cooled to 40 DEG C with
After Xia, natural filtration removes residue, then weight Rotary Evaporators is concentrated into 1/10th, i.e. obtains lavandula angustifolia extracting solution；
(5) by the Herba nepenthis extracting solution of step (1), the Folium Artemisiae Argyi extracting solution of step (2), the fly expelling plum extracting solution of step (3), step
(4) lavandula angustifolia extracting solution, deionized water and ethanol mixing, the speed lower seal at 70 DEG C, 300r/min stirs 6h, i.e. obtains
Herba nepenthis extract mosquito incense liquid.
Embodiment 3
A kind of Herba nepenthis extract mosquito incense liquid, is made up of the medicine of following weight portion:
Herba nepenthis extracting solution 120 parts, Folium Artemisiae Argyi extracting solution 76 parts, fly expelling plum extracting solution 39 parts, lavandula angustifolia extracting solution 12 parts, deionization
45 parts of water and ethanol 35 parts.
The preparation method of above-mentioned Herba nepenthis extract mosquito incense liquid, comprises the steps of:
(1) Herba nepenthis extracting solution: after Herba nepenthis roguing, drying, is cut into the segment of 3cm, sends in super micron mill and is ground into
Mesh granularity is the powder of 350 mesh, and the ethanol of 12 times of quality of addition refluxes at 55 DEG C and extracts 11h, and natural filtration collects filtrate, will
Extracting solution concentrating under reduced pressure is 1/10th of original solution volume, obtains Herba nepenthis extracting solution；
(2) Folium Artemisiae Argyi extracting solution: by Folium Artemisiae Argyi roguing, dry after send in super micron mill and be ground into the powder that mesh granularity is 180 mesh,
Sealing in the ethanol of 10 times of quality of Folium Artemisiae Argyi and soak 2h30min, the temperature of ethanol is 38 DEG C, is then sonicated 37min and obtains Folium Artemisiae Argyi
Solution, then collect centrifuged supernatant the most afterwards, it is concentrated into 1/10th of liquor capacity with Rotary Evaporators, obtains Folium Artemisiae Argyi and carry
Take liquid；
(3) fly expelling plum extracting solution: by fly expelling plum roguing, dry after send in super micron mill that to be ground into mesh granularity be 170 purposes
Powder, seals in the ethanol of 8 times of quality of fly expelling plum and soaks 6h, and the temperature of ethanol is 37 DEG C, is then sonicated 33min and obtains Folium Artemisiae Argyi
Solution, then collect centrifuged supernatant the most afterwards；Gained precipitate adds the ethanol of its quality 6 times to carry out twice ultrasonic and carries
Taking, supersound process 33min obtains fly expelling plum solution, then collects centrifuged supernatant the most afterwards；Merge two times centrifugal supernatant, and use
Rotary Evaporators is concentrated into 1/10th of liquor capacity, obtains fly expelling plum extracting solution；
(4) lavandula angustifolia extracting solution: add the ethanol of 7 times of quality of lavandula angustifolia, reflux, extract, 4h at 75 DEG C, be cooled to less than 40 DEG C
After, natural filtration removes residue, then weight Rotary Evaporators is concentrated into 1/10th, i.e. obtains lavandula angustifolia extracting solution；
(5) by the Herba nepenthis extracting solution of step (1), the Folium Artemisiae Argyi extracting solution of step (2), the fly expelling plum extracting solution of step (3), step
(4) lavandula angustifolia extracting solution, deionized water and ethanol mixing, the speed lower seal at 59 DEG C, 230r/min stirs 4h, i.e. obtains
Herba nepenthis extract mosquito incense liquid.
Embodiment 4
A kind of Herba nepenthis extract mosquito incense liquid, is made up of the medicine of following weight portion:
Herba nepenthis extracting solution 150 parts, Folium Artemisiae Argyi extracting solution 85 parts, fly expelling plum extracting solution 45 parts, lavandula angustifolia extracting solution 16 parts, deionization
55 parts of water and ethanol 50 parts.
The preparation method of above-mentioned Herba nepenthis extract mosquito incense liquid, comprises the steps of:
(1) Herba nepenthis extracting solution: after Herba nepenthis roguing, drying, is cut into the segment of 5cm, sends in super micron mill and is ground into
Mesh granularity is the powder of 450 mesh, and the ethanol of 14 times of quality of addition refluxes at 60 DEG C and extracts 14h, and natural filtration collects filtrate, will
Extracting solution concentrating under reduced pressure is 1/10th of original solution volume, obtains Herba nepenthis extracting solution；
(2) Folium Artemisiae Argyi extracting solution: by Folium Artemisiae Argyi roguing, dry after send in super micron mill and be ground into the powder that mesh granularity is 230 mesh,
Sealing in the ethanol of 12 times of quality of Folium Artemisiae Argyi and soak 3h30min, the temperature of ethanol is 42 DEG C, is then sonicated 43min and obtains Folium Artemisiae Argyi
Solution, then collect centrifuged supernatant the most afterwards, it is concentrated into 1/10th of liquor capacity with Rotary Evaporators, obtains Folium Artemisiae Argyi and carry
Take liquid；
(3) fly expelling plum extracting solution: by fly expelling plum roguing, dry after send in super micron mill that to be ground into mesh granularity be 220 purposes
Powder, seals in the ethanol of 11 times of quality of fly expelling plum and soaks 7h, and the temperature of ethanol is 43 DEG C, and being then sonicated 38min must end
Grass solution, then collect centrifuged supernatant the most afterwards；Gained precipitate adds the ethanol of its quality 8 times to carry out twice ultrasonic and carries
Taking, supersound process 38min obtains fly expelling plum solution, then collects centrifuged supernatant the most afterwards；Merge two times centrifugal supernatant, and use
Rotary Evaporators is concentrated into 1/10th of liquor capacity, obtains fly expelling plum extracting solution；
(4) lavandula angustifolia extracting solution: add 10 times of quality of lavandula angustifolia ethanol, reflux, extract, 5h at 85 DEG C, be cooled to 40 DEG C with
After Xia, natural filtration removes residue, then weight Rotary Evaporators is concentrated into 1/10th, i.e. obtains lavandula angustifolia extracting solution；
(5) by the Herba nepenthis extracting solution of step (1), the Folium Artemisiae Argyi extracting solution of step (2), the fly expelling plum extracting solution of step (3), step
(4) lavandula angustifolia extracting solution, deionized water and ethanol mixing, the speed lower seal at 65 DEG C, 280r/min stirs 5h, i.e. obtains
Herba nepenthis extract mosquito incense liquid.
Embodiment 5
A kind of Herba nepenthis extract mosquito incense liquid, is made up of the medicine of following weight portion:
Herba nepenthis extracting solution 135 parts, Folium Artemisiae Argyi extracting solution 79 parts, fly expelling plum extracting solution 42 parts, lavandula angustifolia extracting solution 14 parts, deionization
50 parts of water and ethanol 46 parts.
The preparation method of above-mentioned Herba nepenthis extract mosquito incense liquid, comprises the steps of:
(1) Herba nepenthis extracting solution: after Herba nepenthis roguing, drying, is cut into the segment of 4cm, sends in super micron mill and is ground into
Mesh granularity is the powder of 400 mesh, and the ethanol of 13 times of quality of addition refluxes at 58 DEG C and extracts 12h, and natural filtration collects filtrate, will
Extracting solution concentrating under reduced pressure is 1/10th of original solution volume, obtains Herba nepenthis extracting solution；
(2) Folium Artemisiae Argyi extracting solution: by Folium Artemisiae Argyi roguing, dry after send in super micron mill and be ground into the powder that mesh granularity is 200 mesh,
Sealing in the ethanol of 11 times of quality of Folium Artemisiae Argyi and soak 3h, the temperature of ethanol is 40 DEG C, is then sonicated 40min and obtains Folium Artemisiae Argyi solution,
Collect centrifuged supernatant the most afterwards, be concentrated into 1/10th of liquor capacity with Rotary Evaporators, obtain Folium Artemisiae Argyi extracting solution；
(3) fly expelling plum extracting solution: by fly expelling plum roguing, dry after send in super micron mill that to be ground into mesh granularity be 200 purposes
Powder, seals in the ethanol of 9 times of quality of fly expelling plum and soaks 6h30min, and the temperature of ethanol is 40 DEG C, is then sonicated 35min
Obtain Folium Artemisiae Argyi solution, then collect centrifuged supernatant the most afterwards；Gained precipitate adds the ethanol of its quality 7 times to carry out secondary and surpasses
Sound extracts, and supersound process 35min obtains fly expelling plum solution, then collects centrifuged supernatant the most afterwards；Merge two times centrifugal supernatant,
And 1/10th of liquor capacity it is concentrated into Rotary Evaporators, obtain fly expelling plum extracting solution；
(4) lavandula angustifolia extracting solution: in the ethanol of 8 times of quality of lavandula angustifolia, reflux, extract, 4h30min at 80 DEG C, be cooled to 40 DEG C
After below, natural filtration removes residue, then weight Rotary Evaporators is concentrated into 1/10th, i.e. obtains lavandula angustifolia and extracts
Liquid；
(5) by the Herba nepenthis extracting solution of step (1), the Folium Artemisiae Argyi extracting solution of step (2), the fly expelling plum extracting solution of step (3), step
(4) lavandula angustifolia extracting solution, deionized water and ethanol mixing, the speed lower seal at 62 DEG C, 250r/min stirs 4h30min,
I.e. obtain Herba nepenthis extract mosquito incense liquid.
The method checking above-mentioned Herba nepenthis extract mosquito incense liquid is as follows.
Test 1: indoor harmacological effect.
(1) abnormal smells from the patient inspection: sense organ, delicate fragrance, nonirritant abnormal flavour.
(2) drug effect inspection: use GB 18418-2001 domestic sanitary parasite killing articles for use electric liquid device standard to survey
Examination.In the standard, it is qualified that KT50 value (boxing method)≤10min can be judged to, this mosquito incense liquid indoor harmacological effect table is shown in Table 1.
Table 1
| Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 | |
| KT50 value | 7min29s | 8min3s | 7min54s | 7min41s | 8min16s |
As it can be seen from table 1 this Herba nepenthis extract mosquito incense liquid meets GB 18418-2001 domestic sanitary parasite killing articles for use electric heating liquid
Body mosquito incense standard, has anophelifuge, sterilizing function.
Test 2: mosquito-repellent incense safety is tested
(1) rat acute Oral toxicity
First the mosquito incense solution of above-mentioned 5 embodiments is carried out gavage to 5 rats respectively, after gavage 40-50min the most without exception instead
Should, the situations such as external reaction is blunt, rat is suffered from diarrhoea, dull do not occur, without rats death during observation, LD50 is more than 5000mg/
Kg, is grouped standard, the Ministry of Agriculture 1.2, the toxicity of 1.8G product and classer's description according to pesticide acute oral and judges all to belong to nontoxic level.
(2) acute inhalation toxicity test
Take the mosquito incense liquid in a certain amount of above-mentioned 5 embodiments, be placed in 5 exposure in static total enclosure chamber cabinets and power up volatilization.Put the most respectively
Enter 5 rats, according to rat acute toxicity on inhalation relevant in GB15670-1995 agriculture chemical registration toxicology test method test into
OK, experimental result is as follows: after contamination, perspiring, breathing the symptoms such as the most slow, activity reduces, external reaction is blunt all do not occur in rat,
Without rats death during observation, LD50 is more than 10g/m3, according to pesticide acute inhalation toxicity grade scale, the Ministry of Agriculture 1.2,1.8G
The toxicity of product and classer's description judge, all belong to nontoxic level.
Test 3: eye irritant test.
Experimental group acute ocular stimulates integration number to be 0, shows that mucosa is had no stimulation by the mosquito incense in the present invention.
Test 4: help for sleep test
The present invention has reached relatively significant effect at the aspect that helps for sleep, and proves its effect by following implementation: main
Method is the aspiration user experiment of mosquito incense liquid, and totally 300 volunteers having some problems in sleep, use above-mentioned 5 respectively
Mosquito incense liquid in embodiment, (is i.e. " Self-reporting inventory-SCL90 ", that the most foremost psychology is good for by SCL-90 questionnaire
One of health test scale) and PSQL(Pittsburgh Sleep Quality Index) questionnaire, followed the tracks of by the uses of continuous 3 weeks, sentence
The actual efficacy effect of the disconnected present invention.All volunteers do not use hypnotic drug in the proximal segment time, all volunteers are divided at random
Being five groups of experimental grouies and one group of matched group, the sex often organized, age, schooling, sleep degree compare, its no statistical difference
Meaning (equal ＞ P0.05), uses Wilcoxon rank test, and inspection level a=0.05, sleep disorder improves statistical result and is shown in Table
2。
Table 2
| Application example | Basic healing | Effective | Take a turn for the better | Invalid | Effective percentage |
| Embodiment 1 | 4(8%) | 26(52%) | 19(38%) | 1(2%) | 98(%) |
| Embodiment 2 | 5(10%) | 27(54%) | 16(32%) | 2(4%) | 96(%) |
| Embodiment 3 | 3(6%) | 25(50%) | 20(40%) | 2(4%) | 96(%) |
| Embodiment 4 | 4(8%) | 28(56%) | 17(34%) | 1(2%) | 98(%) |
| Embodiment 5 | 5(10%) | 29(58%) | 15(30%) | 1(2%) | 98(%) |
By table 2 it can be seen that the Herba nepenthis extract mosquito incense liquid of the present invention can help for sleep, sleep disorder patient is cured
Rate is up to 98%.
(1) application case
Wei, man, 57 years old, difficulty falling asleep occurred before 2 years, the sack time of every day 4-5 hour, the proximal segment time do not uses calmness to urge
Dormancy medicine, after using the mosquito incense liquid 3 weeks of the present invention, the length of one's sleep of every day is 6-7 hour now, he or she's conscious sleep feelings
Condition is clearly better.
Gong, female, 29 years old, insomnia-middle occurred before half a year, easily wakes up with a start that dreaminess is felt sleepy, but be can't fall asleep, often daytime
3-5 hour it length of one's sleep, the proximal segment time do not uses sedative hypnotic drug, after using the mosquito incense liquid 3 weeks of the present invention, the most often
It the length of one's sleep is 6-8 hour, and he or she is conscious, and sleep quality is clearly better.
Wang, man, 49 years old, difficulty falling asleep occurred before 1 year, the most easily wakes up, difficult after waking up fall asleep, the length of one's sleep every day 4-5
Hour, the proximal segment time does not uses sedative hypnotic drug, after using the mosquito incense liquid 3 weeks of the present invention, and the length of one's sleep of every day now
For 6-7 hour, he or she is conscious, and sleep quality was clearly better.
In sum, the Herba nepenthis extract mosquito incense liquid product safety non-toxic of the present invention, preparation is simple, easily operates, suitable
Close commercial production, there is sterilization, anophelifuge, effect of helping for sleep.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie
In the case of the spirit or essential attributes of the present invention, it is possible to realize the present invention in other specific forms.Therefore, nothing
Opinion, from the point of view of which point, all should be regarded embodiment as exemplary, and be nonrestrictive, and the scope of the present invention is by appended
Claim rather than described above limit, it is intended that the institute that will fall in the implication of equivalent loins and scope of claim
Change and include in the present invention.
Although moreover, it will be appreciated that this specification is been described by according to embodiment, but the most each embodiment only comprises
One independent technical scheme, this narrating mode of description is only the most for clarity sake, and those skilled in the art should be by
Description is as an entirety, and the technical scheme in each embodiment can also be through appropriately combined, and forming those skilled in the art can
With other embodiments understood.
Claims (7)
1. a Herba nepenthis extract mosquito incense liquid, it is characterised in that be made up of the medicine of following weight portion: Herba nepenthis extracting solution
110-160 part, Folium Artemisiae Argyi extracting solution 67-94 part, fly expelling plum extracting solution 33-51 part, lavandula angustifolia extracting solution 8-20 part, deionized water
40-60 part and ethanol 30-55 part.
Herba nepenthis extract mosquito incense liquid the most according to claim 1, it is characterised in that by the medicine system of following weight portion
Become: Herba nepenthis extracting solution 120-150 part, Folium Artemisiae Argyi extracting solution 76-85 part, fly expelling plum extracting solution 39-45 part, lavandula angustifolia extracting solution
12-16 part, deionized water 45-55 part and ethanol 35-50 part.
Herba nepenthis extract mosquito incense liquid the most according to claim 1, it is characterised in that by the medicine system of following weight portion
Become: Herba nepenthis extracting solution 135 parts, Folium Artemisiae Argyi extracting solution 79 parts, fly expelling plum extracting solution 42 parts, lavandula angustifolia extracting solution 14 parts, deionization
50 parts of water and ethanol 46 parts.
4. according to the preparation method of the Herba nepenthis extract mosquito incense liquid described in any one of claims 1 to 3, it is characterised in that by
Following steps form:
(1) Herba nepenthis extracting solution: after Herba nepenthis roguing, drying, is cut into the segment of 2-6cm, sends in super micron mill and pulverizes
Becoming powder, the ethanol of 11-15 times of quality of addition refluxes at 50-65 DEG C and extracts 10-15h, filtrate is collected by filtration, and extracting solution is dense
It is condensed to 1/10th of original solution volume, obtains Herba nepenthis extracting solution；
(2) Folium Artemisiae Argyi extracting solution: by Folium Artemisiae Argyi roguing, dry after send in super micron mill and be ground into powder, in 9-13 times of matter of Folium Artemisiae Argyi
The ethanol of amount seals and soaks 2-4h, be then sonicated 35-45min and obtain Folium Artemisiae Argyi solution, then collect centrifuged supernatant the most afterwards,
It is concentrated into 1/10th of liquor capacity with Rotary Evaporators, obtains Folium Artemisiae Argyi extracting solution；
(3) fly expelling plum extracting solution: by fly expelling plum roguing, dry after send in super micron mill and be ground into powder, at fly expelling plum 7-
The ethanol of 12 times of quality seals and soaks 5-8h, be then sonicated 30-40min and obtain Folium Artemisiae Argyi solution, then collect centrifugal the most afterwards
Supernatant；Gained precipitate adds the ethanol of its quality 5-9 times and carries out twice ultrasonic extraction, and supersound process 30-40min must be by
Fly prunus mume (sieb.) sieb.et zucc. solution, then collect centrifuged supernatant the most afterwards；Merge two times centrifugal supernatant, and be concentrated into solution with Rotary Evaporators
/ 10th of volume, obtain fly expelling plum extracting solution；
(4) lavandula angustifolia extracting solution: add the ethanol of 6-11 times of quality of lavandula angustifolia, reflux, extract, 3-6h at 70-90 DEG C, be cooled to
After less than 40 DEG C, natural filtration removes residue, retells weight and is concentrated into 1/10th, i.e. obtains lavandula angustifolia extracting solution；
(5) by the Herba nepenthis extracting solution of step (1), the Folium Artemisiae Argyi extracting solution of step (2), the fly expelling plum extracting solution of step (3), step
(4) lavandula angustifolia extracting solution, deionized water and ethanol mixing, stirs 3-6h at 53-70 DEG C of lower seal, i.e. obtains Herba nepenthis and extract
Thing mosquito incense liquid.
The preparation method of Herba nepenthis extract mosquito incense liquid the most according to claim 4, it is characterised in that: in step (1), institute
The mesh granularity of the powder stated is 300-500 mesh, and described filtering technique is natural filtration, and described concentration technology is dense for decompression
Contracting.
The preparation method of Herba nepenthis extract mosquito incense liquid the most according to claim 4, it is characterised in that: in step (2) and
Step (3), the mesh granularity of described powder is 150-250 mesh, and the temperature of described ethanol is 35-45 DEG C.
The preparation method of Herba nepenthis extract mosquito incense liquid the most according to claim 4, it is characterised in that: in step (5), institute
The mixing speed of the stirring technique stated is 200-300r/min.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108308169A (en) * | 2018-01-24 | 2018-07-24 | 连江县奇达碧海都市旅游开发有限公司 | A kind of fruits and vegetables dried fish drives the preparation method of fly liquid |
| CN112876922A (en) * | 2021-02-03 | 2021-06-01 | 温州环诺新材料科技有限公司 | Mosquito-proof water-based paint for tent and preparation method thereof |
| WO2022021526A1 (en) * | 2020-07-30 | 2022-02-03 | 苏州乾冠新纺织科技有限公司 | Preparation method for mosquito-repellent antibacterial fabric |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102429840A (en) * | 2011-09-22 | 2012-05-02 | 黄馨莹 | Mosquito repellent liquid and preparation method thereof |
| CN103340215A (en) * | 2013-06-14 | 2013-10-09 | 沈阳创达技术交易市场有限公司 | Traditional Chinese medicine spraying agent for repelling mosquitoes |
| CN103834496A (en) * | 2012-11-28 | 2014-06-04 | 马俊杰 | Anti-mosquito laundry detergent |
| CN104970051A (en) * | 2015-06-30 | 2015-10-14 | 俞亮亮 | Nontoxic mosquito-repellent incense liquid and preparation method thereof |
-
2016
- 2016-08-11 CN CN201610654814.6A patent/CN106212519A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102429840A (en) * | 2011-09-22 | 2012-05-02 | 黄馨莹 | Mosquito repellent liquid and preparation method thereof |
| CN103834496A (en) * | 2012-11-28 | 2014-06-04 | 马俊杰 | Anti-mosquito laundry detergent |
| CN103340215A (en) * | 2013-06-14 | 2013-10-09 | 沈阳创达技术交易市场有限公司 | Traditional Chinese medicine spraying agent for repelling mosquitoes |
| CN104970051A (en) * | 2015-06-30 | 2015-10-14 | 俞亮亮 | Nontoxic mosquito-repellent incense liquid and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 《REPELLENCY OF LANTANA CAMARA (VERBENACEAE ) FLOWERS AGAINST AEDES MOSQUITOES》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108308169A (en) * | 2018-01-24 | 2018-07-24 | 连江县奇达碧海都市旅游开发有限公司 | A kind of fruits and vegetables dried fish drives the preparation method of fly liquid |
| WO2022021526A1 (en) * | 2020-07-30 | 2022-02-03 | 苏州乾冠新纺织科技有限公司 | Preparation method for mosquito-repellent antibacterial fabric |
| CN112876922A (en) * | 2021-02-03 | 2021-06-01 | 温州环诺新材料科技有限公司 | Mosquito-proof water-based paint for tent and preparation method thereof |
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