CN106200573A - Chinese medicine enterprise extracts Workshop Production manufacturing execution system (MES) implementation method - Google Patents
Chinese medicine enterprise extracts Workshop Production manufacturing execution system (MES) implementation method Download PDFInfo
- Publication number
- CN106200573A CN106200573A CN201610503177.2A CN201610503177A CN106200573A CN 106200573 A CN106200573 A CN 106200573A CN 201610503177 A CN201610503177 A CN 201610503177A CN 106200573 A CN106200573 A CN 106200573A
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- CN
- China
- Prior art keywords
- implementation method
- work order
- medicinal liquid
- module
- chinese medicine
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- 238000000034 method Methods 0.000 title claims abstract description 38
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 37
- 239000003814 drug Substances 0.000 title claims abstract description 30
- 239000000284 extract Substances 0.000 title claims abstract description 22
- 239000007788 liquid Substances 0.000 claims abstract description 25
- 239000000047 product Substances 0.000 claims abstract description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 12
- 235000021050 feed intake Nutrition 0.000 claims abstract description 9
- 239000002244 precipitate Substances 0.000 claims abstract description 6
- 239000006071 cream Substances 0.000 claims abstract description 5
- 238000012795 verification Methods 0.000 claims description 7
- 238000007689 inspection Methods 0.000 claims description 3
- 238000005070 sampling Methods 0.000 claims description 3
- 235000013399 edible fruits Nutrition 0.000 claims 1
- 238000000605 extraction Methods 0.000 description 8
- 230000000694 effects Effects 0.000 description 6
- 239000012141 concentrate Substances 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 3
- 238000007726 management method Methods 0.000 description 3
- 239000004480 active ingredient Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000005304 joining Methods 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 238000012552 review Methods 0.000 description 2
- 238000010079 rubber tapping Methods 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 1
- 238000012550 audit Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 238000002203 pretreatment Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000001550 time effect Effects 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
- G05B19/00—Programme-control systems
- G05B19/02—Programme-control systems electric
- G05B19/418—Total factory control, i.e. centrally controlling a plurality of machines, e.g. direct or distributed numerical control [DNC], flexible manufacturing systems [FMS], integrated manufacturing systems [IMS] or computer integrated manufacturing [CIM]
- G05B19/41875—Total factory control, i.e. centrally controlling a plurality of machines, e.g. direct or distributed numerical control [DNC], flexible manufacturing systems [FMS], integrated manufacturing systems [IMS] or computer integrated manufacturing [CIM] characterised by quality surveillance of production
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
- G05B2219/00—Program-control systems
- G05B2219/30—Nc systems
- G05B2219/31—From computer integrated manufacturing till monitoring
- G05B2219/31316—Output test result report after testing, inspection
Landscapes
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Manufacturing & Machinery (AREA)
- Quality & Reliability (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Automation & Control Theory (AREA)
- Medical Treatment And Welfare Office Work (AREA)
Abstract
The invention discloses a kind of Chinese medicine enterprise and extract Workshop Production manufacturing execution system (MES) implementation method, including step be: (1) creates work order；(2) technological parameter is downloaded；(3) feed intake；(4) medicinal liquid extracts；(5) medicinal liquid is carried out economic benefits and social benefits concentration；(6) medicinal liquid is carried out precipitate with ethanol；(7) medicinal liquid is carried out single-action concentration；(8) carry out medicinal liquid receiving cream；(9) censorship；(10) statement.By the way, present invention achieves electronics batch record in tcm manufacturing process and substitute papery batch record, data traceability is easy, data integrity strengthens, ERP system from upper strata downloads creation data to obtaining creation data from the automated system of bottom, two systems of perfect series connection, and improve process batch stability in production process, product data trackability and product quality.
Description
Technical field
The present invention relates to Chinese medicine manufacture and perform management domain, be specifically related to Chinese medicine manufacturing process management and control functional area, especially
Relate to a kind of Chinese medicine enterprise and extract Workshop Production manufacturing execution system (MES) implementation method.
Background technology
Chemical analysis contained by Chinese medicine is sufficiently complex, has both contained multiple active ingredient, has contained again multiple invalid element, it is possible to
Toxic substance can be included.Chinese medicine extraction utilizes some technology to extract wherein active ingredient to greatest extent exactly so that Chinese medicine system
The inherent quality of agent and clinical therapeutic efficacy improve, and make the effect of Chinese medicine be played to greatest extent.The extraction of Chinese medicine produces
Mainly including Chinese crude drug pre-treatment, Chinese crude drug extracts, and the separation of extracting solution, purification, concentrates, the technical process such as is dried.Chinese medicine
Extract to produce and typically carry out in the extraction workshop of Chinese medicine enterprise, need to carry out producing to perform operation, but Chinese medicine manufacture at present is held
During row, there is the problems such as batch record data are complete, data completely can not get strict monitoring and review, difficulty is reviewed.
Summary of the invention
The technical problem that present invention mainly solves is to provide a kind of Chinese medicine enterprise and extracts Workshop Production manufacturing execution system
(MES) implementation method, has the advantages such as easy, the data integrity enhancing of data traceability.
For solving above-mentioned technical problem, the technical scheme that the present invention uses is: provide a kind of Chinese medicine enterprise to extract car
Between manufacture execution system (MES) implementation method, including step be: (1) create work order；(2) technological parameter is downloaded；(3) throw
Material；(4) medicinal liquid extracts；(5) medicinal liquid is carried out economic benefits and social benefits concentration；(6) medicinal liquid is carried out precipitate with ethanol；(7) medicinal liquid is carried out single-action concentration；
(8) carry out medicinal liquid receiving cream；(9) censorship；(10) statement.
In a preferred embodiment of the present invention, creating work order described in step (1) is to issue requirement wound according to ERP scheduling
Build.
In a preferred embodiment of the present invention, step (1) also includes issuing work order, and described issue work order is by establishment
Work order is issued.
In a preferred embodiment of the present invention, step (1) also includes the work order that examination & verification is issued, the work that described examination & verification is issued
It is singly that the work order of issue is audited.
In a preferred embodiment of the present invention, feeding intake described in step (3) is to arrange the module that feeds intake, and feeds intake according to described
The display of module, treating feeds intake carry out bar code scan after feed intake.
In a preferred embodiment of the present invention, it is to be connected according to technological process with automatization that step (4) herb liquid extracts
Obtain and extract.
In a preferred embodiment of the present invention, step (8) also includes that extractum is stated, the statement of described extractum is to extractum amount
Statement.
In a preferred embodiment of the present invention, censorship described in step (9) is during obtaining data, to production
In operation and data carry out signature and examine, process and record in electronics batch record, and sampling inspection.
In a preferred embodiment of the present invention, statement described in step (10) is that the result according to censorship carries out product and puts
OK, final statement product, ultimately generate the batch record of electronic edition.
In a preferred embodiment of the present invention, described Chinese medicine enterprise extracts Workshop Production manufacturing execution system (MES) and is
ERP system from upper strata downloads creation data to obtaining creation data from the automated system of bottom.
The invention has the beneficial effects as follows: the Chinese medicine enterprise of the present invention extracts Workshop Production manufacturing execution system (MES) and realizes
Method, be data in related process flow process are collected, the method for deviation processing, solve current Chinese medicine manufacture perform process
In, the difficult problems such as batch record data are not complete, difficulty is reviewed, it is achieved that in tcm manufacturing process, electronics batch record substitutes papery batch record,
Data traceability is easy, and data integrity strengthens.ERP system from upper strata downloads creation data to from the automated system of bottom
Obtaining creation data, two systems of perfect series connection, and improve process batch stability in production process, product data can be reviewed
Property and product quality.
Accompanying drawing explanation
For the technical scheme being illustrated more clearly that in the embodiment of the present invention, in embodiment being described below required for make
Accompanying drawing be briefly described, it should be apparent that, below describe in accompanying drawing be only some embodiments of the present invention, for
From the point of view of those of ordinary skill in the art, on the premise of not paying creative work, it is also possible to obtain other according to these accompanying drawings
Accompanying drawing, wherein:
Fig. 1 is that the Chinese medicine enterprise of the present invention extracts the preferred embodiment of Workshop Production manufacturing execution system (MES) implementation method one
Flow chart；
Fig. 2 is the interface display figure of work order creation module one of the present invention preferred embodiment；
Fig. 3 is the interface display figure of work order release module one of the present invention preferred embodiment；
Fig. 4 is the interface display figure that the present invention audits work order one preferred embodiment of issue；
Fig. 5 is the interface display figure of present invention process parameter module one preferred embodiment；
Fig. 6 is that the present invention feeds intake the interface display figure of module one preferred embodiment；
Fig. 7 is the interface display figure of extraction module one of the present invention preferred embodiment；
Fig. 8 is the interface display figure that economic benefits and social benefits of the present invention concentrate module one preferred embodiment；
Fig. 9 is the interface display figure of extractum declaration module one of the present invention preferred embodiment；
Figure 10 is the interface display figure of censorship module one of the present invention preferred embodiment.
Detailed description of the invention
Technical scheme in the embodiment of the present invention will be clearly and completely described below, it is clear that described enforcement
Example is only a part of embodiment of the present invention rather than whole embodiments.Based on the embodiment in the present invention, this area is common
All other embodiments that technical staff is obtained under not making creative work premise, broadly fall into the model of present invention protection
Enclose.
Refer to Fig. 1, it is provided that a kind of Chinese medicine enterprise extracts Workshop Production manufacturing execution system (MES) implementation method, including
Step is:
(1) creating work order, described establishment work order issues requirement according to ERP scheduling and creates.Described establishment work order specially sets
Putting work order creation module, described work order creation module includes work order number module, work order type block, client's work order class pattern
Block, batch parameter module, formula module, describing module, effect duration starts module, effect duration terminates module, product module, manufacture
Describing module, type block, main describing module, stability module, overall status module, quantity module, with reference to quantity module,
Weighing module, work order amount module, recipe list module of equal value, the concrete interface display figure of work order creation module is shown in Fig. 2.Described work
Single numbering module display work order number, described work order type block display work order type, described client's work order type block shows
Client's work order type, described batch parameter module display batch parameter, the label of described formula module display formula, each formula
The corresponding corresponding formula content of label, described describing module shows the content that work order describes, and described effect duration starts module and shows
Time started effect duration, described effect duration terminate module display end time effect duration, described product module display product corresponding
Label, the workshop section that the display of described manufacture describing module manufactures describes, the display main description of work order of described main describing module,
Described stability module exhibit stabilization, described overall status module display overall status, described quantity module, described reference number
Amount module, described Weighing module of equal value, described work order amount module display weight number, described recipe list module shows concrete joining
Side, weighs including coding, the description of Chinese medicine title, quantity, unit, fixed qty, stage, order, D, batch, dispensing, manufactures
Weigh, packaging weighs, use titer, QS, S, medicine to weigh pattern.
(2) issuing work order, described issue work order is the work order of establishment to be issued, and described issue work order is specially and arranges
Work order release module, the concrete interface display figure of work order release module is shown in Fig. 3.
(3) work order that examination & verification is issued, the work order that described examination & verification is issued is the work order of issue to be audited；Described examination & verification is sent out
The work order of cloth be by inputting user name, password, note carry out confirming to log in, concrete interface display figure is shown in Fig. 4.
(4) download technological parameter, select each manufacturing process in extraction of traditional Chinese medicine, corresponding technological parameter is carried out
Download；Described download technological parameter is by arranging the realization of technological parameter module, the concrete interface display figure of technological parameter module
See that Fig. 5, described technological parameter module include multiple parameter name module and corresponding parameter value module, described parameter name module
The title of the parameter needed in display manufacturing process, the parameter value that described parameter value module display parameters are corresponding.
(5) feed intake, described in feed intake by setting feed intake module realize, according to the display of the described module that feeds intake, treat
Feed intake and feed intake after carrying out bar code scan.The concrete interface display of the described module that feeds intake is shown in Fig. 6, described in the module that feeds intake include joining
Side's describing module and recipe list module, the essential information of described formula describing module display formula, described recipe list module
Show concrete formula.
(6) medicinal liquid extracts, and is to be connected with automatization to obtain according to technological process to extract, and it is by arranging that described medicinal liquid extracts
Extraction module realizes, and concrete interface display is shown in Fig. 7.Described extraction module includes extracting information module and operator's module,
Described extraction information module display tapping time started, tapping end time, medicinal liquid storage tank number, amount of liquid medicine etc. are extracted process and are shown
Information, described operator's module display name of process operator and code.
(7) medicinal liquid carrying out economic benefits and social benefits concentration, described economic benefits and social benefits concentrate by arranging economic benefits and social benefits concentration module realization, concrete boundary
Face shows sees Fig. 8.Described economic benefits and social benefits concentrate module display economic benefits and social benefits and concentrate the selection information of concrete equipment.
(8) medicinal liquid carrying out precipitate with ethanol, the operation of described precipitate with ethanol is similar with economic benefits and social benefits concentration step.
(9) medicinal liquid carrying out single-action concentration, described single-action concentration operation is similar with economic benefits and social benefits concentration step.
(10) medicinal liquid carries out receiving cream, and the operation of described receipts cream is similar with precipitate with ethanol step.
(11) extractum statement, the statement of described extractum realizes by arranging extractum declaration module, and concrete interface display is shown in
Fig. 9.The statement of described extractum includes unstated extractum amount, extractum amount, the statement time of this time statement, whether continues statement.
(12) censorship, during obtaining data, carries out signature to the operation in producing and data and examines, process and remember
Record in electronics batch record, sampling inspection.Described censorship is realized by censorship module, and concrete interface display is shown in Figure 10.
(12) statement, carries out product clearance, final statement product according to the result of censorship, ultimately generates batch note of electronic edition
Record.
The present invention is directed to the data during current Chinese medicine manufacture performs completely can not get strict monitoring and review etc. and ask
Topic, it is provided that a kind of software realizes performing fully according to process steps, real time data acquisition is examined in strict accordance with corresponding authority
Criticizing and the management and control of deviation, the batch record ultimately generating electronic edition examines, is completely generated the data that process is complete.
The foregoing is only embodiments of the invention, not thereby limit the scope of the claims of the present invention, every utilize this
Equivalent structure or equivalence flow process that bright description is made convert, or are directly or indirectly used in other relevant technology neck
Territory, is the most in like manner included in the scope of patent protection of the present invention.
Claims (10)
1. a Chinese medicine enterprise extracts Workshop Production manufacturing execution system (MES) implementation method, it is characterised in that include step
For: (1) creates work order；(2) technological parameter is downloaded；(3) feed intake；(4) medicinal liquid extracts；(5) medicinal liquid is carried out economic benefits and social benefits concentration；(6)
Medicinal liquid is carried out precipitate with ethanol；(7) medicinal liquid is carried out single-action concentration；(8) carry out medicinal liquid receiving cream；(9) censorship；(10) statement.
Implementation method the most according to claim 1, it is characterised in that creating work order described in step (1) is to arrange according to ERP
Give birth to send out and require establishment.
Implementation method the most according to claim 1, it is characterised in that step (1) also includes issuing work order, described issue work
It is singly that the work order of establishment is issued.
Implementation method the most according to claim 3, it is characterised in that step (1) also includes the work order that examination & verification is issued, described
The work order that examination & verification is issued is the work order of issue to be audited.
Implementation method the most according to claim 1, it is characterised in that feeding intake described in step (3) is to arrange the module that feeds intake,
According to the display of the described module that feeds intake, treating feeds intake carry out bar code scan after feed intake.
Implementation method the most according to claim 1, it is characterised in that it is to be connected with automatization that step (4) herb liquid extracts
Obtain according to technological process and extract.
Implementation method the most according to claim 1, it is characterised in that step (8) also includes that extractum is stated, described extractum sound
Bright is the statement to extractum amount.
Implementation method the most according to claim 1, it is characterised in that censorship described in step (9) is obtaining data
During, the operation in producing and data are carried out signature and examines, process and record in electronics batch record, and sampling inspection.
Implementation method the most according to claim 1, it is characterised in that described in step (10), statement is the knot according to censorship
Fruit carries out product clearance, final statement product, ultimately generates the batch record of electronic edition.
Implementation method the most according to claim 1, it is characterised in that described Chinese medicine enterprise extracts Workshop Production manufacture and holds
Row system (MES) is that the ERP system from upper strata downloads creation data to obtaining creation data from the automated system of bottom.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610503177.2A CN106200573A (en) | 2016-07-01 | 2016-07-01 | Chinese medicine enterprise extracts Workshop Production manufacturing execution system (MES) implementation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610503177.2A CN106200573A (en) | 2016-07-01 | 2016-07-01 | Chinese medicine enterprise extracts Workshop Production manufacturing execution system (MES) implementation method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106200573A true CN106200573A (en) | 2016-12-07 |
Family
ID=57462587
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610503177.2A Pending CN106200573A (en) | 2016-07-01 | 2016-07-01 | Chinese medicine enterprise extracts Workshop Production manufacturing execution system (MES) implementation method |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107582600A (en) * | 2017-06-26 | 2018-01-16 | 安徽永生堂药业有限责任公司 | A kind of banlangen granules, banlangen keli and preparation method thereof |
| CN108846648A (en) * | 2018-07-25 | 2018-11-20 | 河南太龙药业股份有限公司 | The with no paper monitoring system of production process and monitoring method |
| CN112101771A (en) * | 2020-09-10 | 2020-12-18 | 重庆华森制药股份有限公司 | Automatic production control system and production method for Danshu soft capsules |
| CN112365245A (en) * | 2020-11-30 | 2021-02-12 | 太极集团重庆涪陵制药厂有限公司 | Traditional Chinese medicine extraction production management method |
| CN117250923A (en) * | 2023-09-25 | 2023-12-19 | 浙江迦楠智药科技有限公司 | Process, production and equipment operation linkage control method for pharmaceutical production line |
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Cited By (5)
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| CN112365245A (en) * | 2020-11-30 | 2021-02-12 | 太极集团重庆涪陵制药厂有限公司 | Traditional Chinese medicine extraction production management method |
| CN117250923A (en) * | 2023-09-25 | 2023-12-19 | 浙江迦楠智药科技有限公司 | Process, production and equipment operation linkage control method for pharmaceutical production line |
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Inventor after: Liu Xuesong Inventor after: Chen Yong Inventor after: Xiao Wei Inventor after: Lin Zhizhan Inventor after: Yan Huahui Inventor after: Li Yerui Inventor before: Liu Xuesong Inventor before: Chen Yong Inventor before: Lin Zhizhan Inventor before: Yan Huahui Inventor before: Li Yerui |
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Application publication date: 20161207 |