CN106139226A - A kind of medical sponge and preparation method thereof - Google Patents
A kind of medical sponge and preparation method thereof Download PDFInfo
- Publication number
- CN106139226A CN106139226A CN201610759628.9A CN201610759628A CN106139226A CN 106139226 A CN106139226 A CN 106139226A CN 201610759628 A CN201610759628 A CN 201610759628A CN 106139226 A CN106139226 A CN 106139226A
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- Prior art keywords
- sponge
- ingredient
- medical sponge
- micropore
- base material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/425—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/23—Carbohydrates
- A61L2300/232—Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
Abstract
The invention discloses a kind of medical sponge and preparation method thereof.Concrete, the present invention discloses a kind of medical sponge with bacterio static itching-relieving effect, including, base material and the ingredient that impregnated in base material, wherein said base material is hydrophilic polyurethane foam material.On the other hand, present invention also offers the preparation method of described medical sponge.Medical sponge provided by the present invention has antipruritic, antibacterial, convergence granulation promoting, skin care function.
Description
Technical field
The present invention relates to medical field of new, be specifically related to a kind of medical sponge and preparation method thereof, particularly relate to
A kind of medical sponge with bacterio static itching-relieving effect with hydrophilic polyurethane foam material as base material and preparation method thereof.
Background technology
Varicosis is the modal disease of Venous system, and the main cause of formation is to maintain identical posture very because of long-time
Few change, blood accumulation lower limb, in the case of accumulating over a long period, destroy vein valve and to produce venous pressure too high, cause vein bent
?.Varicosis mostly occurs at lower limb, and leg skin is emerged redness or blueness, seems Aranea, the distortion blood vessel of Lumbricus, or
Lump tuberosity, there is abnormal expansion swelling and varicose in vein, due to venous congestion, can produce inflammation and ulcer and occur continuing
Property pain.A kind of complication of diabetes is ulcer of foot: be commonly called as " diabetic foot ", mainly by lower limb nerve affection and vascular lesion
In addition local compression even damages caused.
Skin around leg inflammation is the most fragile, is therefore easy to impaired, and patient is often the most painful.Most
Patient is to carry out antipruritic pain relieving by wiping liquid medicine or smearing ointment, and practical effect is unsatisfactory.
CN101053668B discloses the preparation method of nanometer calamine compositing hydrogel wound dressing, the wound of this invention
Dressing contains nanometer Calamina and hydrogel, has high-hydroscopicity and the biocompatibility of hydrogel, the most also has nanometer stove
Antibacterial, the convergence of Calamina and the function such as antipruritic.But it is because the hydrogel parcel to Calamina, have impact on the release of Calamina.
CN105031706A discloses the preparation method of a kind of polyvinyl alcohol medical sponge, and such foamed materials has excellence
Water absorbing properties, but its rigid foam that to be impact strength under dry state high, modulus of elasticity in comperssion is big, just can become after water suction
Become whippy material, therefore bring to patient inadaptable.
Summary of the invention
For the deficiencies in the prior art, it is desirable to provide one has antipruritic, antibacterial, convergence granulation promoting, skin care
The nursing dressing of function.
For reaching above-mentioned purpose, the invention provides a kind of medical sponge and preparation method thereof.
First aspect, the invention provides a kind of medical sponge, and it includes, base material becomes with the medicine that impregnated in base material
Point, wherein said base material is hydrophilic polyurethane foam material.Preferably, the quality of described ingredient accounts for the total matter of medical sponge
The 30% ~ 70% of amount..
In above-mentioned medical sponge, it is preferable that the thickness of described hydrophilic polyurethane foam material is 1 ~ 3 millimeter, material internal
Micropore radius of curvature is 0.1 ~ 0.7 millimeter, and can mutual UNICOM between micropore.It is furthermore preferred that described hydrophilic polyurethane bubble
The thickness of foam material is 2 millimeters, and the micropore radius of curvature of material internal is 0.5 millimeter, and the ingredient of sponge absorbing load bearing is
180g/m²
Further, in medical sponge described above, described ingredient comprises, glycerol 2% ~ 10%(w/w), Calamina
0.5% ~ 10%(w/w), ultra-pure water 80% ~ 90%(w/w), zincon 0.1% ~ 0.8%(w/w) and chitosan 0.5% ~ 5%(w/w).More
Preferably, described ingredient comprises, glycerol 6%(w/w), Calamina 8%(w/w), ultra-pure water 84.6%(w/w), zincon
0.4%(w/w) with chitosan 1%(w/w).
In above-mentioned medical sponge, described zincon is selected from: the one or several in zinc, zinc oxide, Zinc alginate calcium and zinc phosphate
Kind.Described hydrophilic polyurethane foam material is opening sponge.
On the other hand, present invention also offers the preparation method of a kind of described medical sponge material, including:
(1) base material: using hydrophilic polyurethane foam material as base material, thickness is 1 ~ 3 millimeter, the micropore curvature of material internal
Radius 0.1 ~ 0.7 millimeter, and can mutual UNICOM between micropore.
(2) preparation of ingredient: take glycerol 2% ~ 10%(w/w) and Calamina 0.5% ~ 10%(w/w) be sufficiently mixed, so
Rear addition ultra-pure water 80% ~ 90%(w/w), it is uniformly mixed, sequentially adds containing zincon 0.1% ~ 0.8%(w/w and chitosan
0.5% ~ 5%(w/w), stand-by after stirring.
(3) on padder, the ingredient that step (2) prepares is impregnated in sponge prepared by step (1), controls
Padding pressure is 0.4kg, and the ingredient of sponge absorbing load bearing is 120 g/m ~ 220g/m.
Optional, said method also includes, step (3) is prepared and rolls up greatly semi-finished product, bundling, cuts, packs, and obtains
Final products, to facilitate use.
The invention provides a kind of described medical sponge material and preferably employ hydrophilic opening sponge, it can continue
Ground, equably release Calamina and containing the ingredient such as zincon.Particularly the when of micropore radius of curvature 0.5 millimeter, effect is
Good, research finds that micropore radius of curvature is too big, and ingredient release ratio is very fast；Micropore radius of curvature is the least, and ingredient discharges
Slow.
On the other hand, the present invention provide medical sponge, structure has porous, mutual UNICOM between micropore, oxygen with
Carbon dioxide almost can pass through completely, and, beneficially pharmaceutical-impregnated composition；The medical sponge that the present invention provides only also has
Itch, antibacterial, convergence granulation promoting, skin care function.The hydrophilic polyurethane foam material used is as base material, and quality is soft, makes
Patient uses comfortable, has preferable protective effect to wound surface；Additionally, also have nontoxic, use safety, good biocompatibility
Advantage.
Accompanying drawing explanation
Fig. 1 shows the schematic diagram of the first aid bleeding-stopping dressing that the present invention provides.
Specific embodiment
Below in conjunction with specific embodiment, technical scheme and beneficial effect done explaination further.Should be appreciated that
These embodiments are merely to illustrate the present invention, rather than limit the scope of the present invention.Further, those skilled in the art are to this
The bright various changes that need not pay creative work or amendment, these equivalent form of values also fall within the application claim institute
The scope limited.
With reference to Fig. 1, medical opening sponge provided by the present invention, its base material is hydrophilic polyurethane foam material 1, and it is thick
Degree is 1 ~ 3 millimeter, and internal micropore radius of curvature 2 is 0.1 ~ 0.7 millimeter, and can mutual UNICOM between micropore；Described doctor
It is that 120 g/m ~ 220g/m is immersed in sponge by the ingredient of sponge absorbing load bearing.
Embodiment 1
Formula:
Base material: sponge thickness 2 millimeters, the radius of curvature of micropore 0.5 millimeter, the ingredient of sponge absorbing load bearing is 180g/m；
Ingredient: glycerol 6%, ultra-pure water 84.6%, Calamina 8%, containing zincon 0.4%, chitosan 1%.
Preparation method:
1) using hydrophilic polyurethane foam material, for opening sponge, thickness is 2 millimeters, the micropore radius of curvature of material internal
0.5 millimeter, and between micropore can mutually UNICOM, beneficially pharmaceutical-impregnated composition, also, it helps during Shi Yonging, medicine
The release of composition；
2) preparation of ingredient, takes 3kg glycerol and 4kg Calamina is sufficiently mixed, and is subsequently adding 42.3kg ultra-pure water, stirring
Mix homogeneously, sequentially adds 200g and contains zincon and 500g chitosan, stand-by after stirring；
3) ingredient prepared being impregnated in sponge on padder, controlling to pad pressure is 0.4kg, and sponge absorbs to be held
The ingredient carried is 200g/m；
4) step 3 obtained rolls up greatly semi-finished product, bundling, cuts, packs, and obtains final products.
Embodiment 2
1) using hydrophilic polyurethane foam material, for opening sponge, thickness is 2 millimeters, the micropore radius of curvature of material internal
0.2 millimeter, and can mutual UNICOM between micropore；
2) preparation of ingredient, takes 5kg glycerol and 1.5kg Calamina is sufficiently mixed, and is subsequently adding 42.3kg ultra-pure water, stirs
Mix mix homogeneously, sequentially add 350g and contain zincon and 1000g chitosan, stand-by after stirring；
3) ingredient prepared being impregnated in sponge on padder, controlling to pad pressure is 0.8kg, and sponge absorbs to be held
The ingredient carried is 150g/m；
4) step 3 obtained rolls up greatly semi-finished product, bundling, cuts, packs, and obtains final products.
Claims (10)
1. a medical sponge, including, base material and the ingredient that impregnated in base material, wherein said base material is the poly-ammonia of hydrophilic
Ester foamed materials.
Medical sponge the most according to claim 1, it is characterised in that it is total that the quality of described ingredient accounts for medical sponge
The 30% ~ 70% of quality.
Medical sponge the most according to claim 2, it is characterised in that the thickness of described hydrophilic polyurethane foam material
Being 1 ~ 3 millimeter, the micropore radius of curvature of material internal is 0.1 ~ 0.7 millimeter, and can mutual UNICOM between micropore.
Medical sponge the most according to claim 3, it is characterised in that described ingredient comprises, glycerol 2% ~ 10%
(w/w), Calamina 0.5% ~ 10%(w/w), ultra-pure water 80% ~ 90%(w/w), zincon 0.1% ~ 0.8%(w/w) and chitosan 0.5%
~ 5%(w/w).
Medical sponge the most according to claim 4, it is characterised in that described ingredient comprises, glycerol 6%(w/
W), Calamina 8%(w/w), ultra-pure water 84.6%(w/w), zincon 0.4%(w/w) and chitosan 1%(w/w).
Medical sponge the most according to claim 5, it is characterised in that the thickness of hydrophilic polyurethane foam material is 2 millis
Rice, the micropore radius of curvature of material internal is 0.5 millimeter, and the ingredient of sponge absorbing load bearing is 180g/m.
Medical sponge the most according to claim 6, it is characterised in that described zincon is selected from: zinc, zinc oxide, Zinc alginate
One or more in calcium and zinc phosphate.
8. according to the medical sponge described in any one of claim 1 ~ 7, it is characterised in that described hydrophilic polyurethane foam material
Material is opening sponge.
9. the preparation method of the medical sponge described in any one of claim 1 ~ 7, including,
(1) base material: using hydrophilic polyurethane foam material as base material, thickness is 1 ~ 3 millimeter, the micropore curvature of material internal
Radius 0.1 ~ 0.7 millimeter, and can mutual UNICOM between micropore；
(2) preparation of ingredient: take glycerol 2% ~ 10%(w/w) and Calamina 0.5% ~ 10%(w/w) be sufficiently mixed, then add
Enter ultra-pure water 80% ~ 90%(w/w), it is uniformly mixed, sequentially adds containing zincon 0.1% ~ 0.8%(w/w and chitosan 0.5%
~ 5%(w/w), stand-by after stirring；
(3) on padder, the ingredient that step (2) prepares is impregnated in sponge prepared by step (1), controls to pad
Pressure is 0.4kg, and the ingredient of sponge absorbing load bearing is 120 g/m ~ 220g/m.
Preparation method the most according to claim 9, it is characterised in that also include, prepares big volume half by step (3)
Finished product, bundling, cuts, packs, and obtains final products.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610759628.9A CN106139226A (en) | 2016-08-30 | 2016-08-30 | A kind of medical sponge and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610759628.9A CN106139226A (en) | 2016-08-30 | 2016-08-30 | A kind of medical sponge and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106139226A true CN106139226A (en) | 2016-11-23 |
Family
ID=57344499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610759628.9A Pending CN106139226A (en) | 2016-08-30 | 2016-08-30 | A kind of medical sponge and preparation method thereof |
Country Status (1)
| Country | Link |
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| CN (1) | CN106139226A (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004028400A2 (en) * | 2002-08-20 | 2004-04-08 | General Wound Kare, Inc. (A Corporation Of Deleware) | Medical pad, and method for making and using |
| CN1895683A (en) * | 2005-07-12 | 2007-01-17 | 深圳市爱杰特医药科技有限公司 | Nanometer-silver antibacterial coating, its preparation and use |
| CN102078639A (en) * | 2009-11-26 | 2011-06-01 | 许高琴 | Medicine carrying method of medical sponge |
| CN203244673U (en) * | 2013-05-08 | 2013-10-23 | 中国人民解放军第四五五医院 | Sealed negative pressure drainage device containing nano-silver polyurethane dressing |
| CN104189004A (en) * | 2014-09-04 | 2014-12-10 | 湖南尔康湘药制药有限公司 | Production method of calamine lotion |
| CN104667334A (en) * | 2015-03-24 | 2015-06-03 | 深圳市源兴纳米医药科技有限公司 | Foam dressing containing composite silver-zinc antibacterial material and preparation method of foam dressing |
-
2016
- 2016-08-30 CN CN201610759628.9A patent/CN106139226A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004028400A2 (en) * | 2002-08-20 | 2004-04-08 | General Wound Kare, Inc. (A Corporation Of Deleware) | Medical pad, and method for making and using |
| CN1895683A (en) * | 2005-07-12 | 2007-01-17 | 深圳市爱杰特医药科技有限公司 | Nanometer-silver antibacterial coating, its preparation and use |
| CN102078639A (en) * | 2009-11-26 | 2011-06-01 | 许高琴 | Medicine carrying method of medical sponge |
| CN203244673U (en) * | 2013-05-08 | 2013-10-23 | 中国人民解放军第四五五医院 | Sealed negative pressure drainage device containing nano-silver polyurethane dressing |
| CN104189004A (en) * | 2014-09-04 | 2014-12-10 | 湖南尔康湘药制药有限公司 | Production method of calamine lotion |
| CN104667334A (en) * | 2015-03-24 | 2015-06-03 | 深圳市源兴纳米医药科技有限公司 | Foam dressing containing composite silver-zinc antibacterial material and preparation method of foam dressing |
Non-Patent Citations (2)
| Title |
|---|
| 张莉等: "亲水性聚氨酯在医用敷料方面的应用", 《化学推进剂与高分子材料》 * |
| 徐洪璋等: "复合溃愈速明胶海绵的制备及其性能分析", 《中国医药导报》 * |
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Application publication date: 20161123 |
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