CN106137485B - Sacculus and stent delivery system - Google Patents

Sacculus and stent delivery system Download PDF

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Publication number
CN106137485B
CN106137485B CN201510154990.9A CN201510154990A CN106137485B CN 106137485 B CN106137485 B CN 106137485B CN 201510154990 A CN201510154990 A CN 201510154990A CN 106137485 B CN106137485 B CN 106137485B
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China
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sacculus
straight portion
holder
length
proximal
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CN106137485A (en
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徐亚鹏
岳斌
李俊菲
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Shanghai Microport Medical Group Co Ltd
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Shanghai Microport Medical Group Co Ltd
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Abstract

The sacculus and stent delivery system of the present invention, sacculus includes the nearly pipe end being sequentially connected, nearly tapering, sacculus straight portion, remote tapering and remote pipe end, further include Proximal transition section and/or distal transition, the Proximal transition section connects the nearly tapering and the sacculus straight portion, the distal transition connects the sacculus straight portion and the remote tapering, and the wall thickness of the Proximal transition section and/or the distal transition is different from the wall thickness of sacculus straight portion.In the present invention, Proximal transition section and/or the distal transition is respectively set at the both ends of sacculus straight portion, by selecting the relative length between sacculus straight portion and holder, and the relativeness of the wall thickness of the wall thickness and sacculus straight portion of corresponding Proximal transition section and/or distal transition, to theres is a phenomenon where dog bone or expand not open when preventing implantation holder, and length of realization under conditions of not changing holder original size after control stenter to implant.

Description

Sacculus and stent delivery system
Technical field
The invention belongs to the field of medical instrument technology more particularly to a kind of sacculus and stent delivery system.
Background technology
Cardiac stent operation can significantly improve deficiency myocardial blood supply caused by coronary heart disease and heart arter obstruction.Heart The process of stent procedure treatment is puncture vessel, and conduit is made to move ahead in the blood vessel, is reached at coronary ostium, then using medical Holder is transported to the position for needing to place by polymeric delivery system, is placed, is withdrawn from conduit, terminates operation.Likewise, encephalic branch Frame operation is the operation narrow for treating intracranial vessel, and holder is transported to the portion for needing to place using polymeric delivery system Position.
In general, cardiac stent, intracranial stent and other endovascular stents often require to use sacculus as carrier, incite somebody to action Corresponding position in stenter to implant human body.Since the length of holder in the prior art is that discrete, different holder needs to match Different sacculus are expanded, when lacking the holder of a certain specific length, it is necessary to correspondingly elongate or shorten holder with more Cover diseased region well.
Invention content
The object of the present invention is to provide a kind of sacculus, by the way that proximal end step, the distal end step of sacculus is arranged, and control Relative length between sacculus straight portion and holder can control holder and plant under conditions of not changing holder original size Length after entering, to better cover diseased region.
To solve the above-mentioned problems, the present invention provides a kind of sacculus, including nearly pipe end, nearly tapering, the sacculus being sequentially connected Straight portion, remote tapering and remote pipe end further include Proximal transition section and/or distal transition, the Proximal transition section connection The nearly tapering and the sacculus straight portion, the distal transition connect the sacculus straight portion and the remote tapering, And the wall thickness of the Proximal transition section and/or the distal transition is different from the wall thickness of sacculus straight portion.
Optionally, the wall of sacculus straight portion described in the wall ratio of the Proximal transition section and/or the distal transition Thick 1%-30%.
Optionally, the wall of sacculus straight portion described in the wall ratio of the Proximal transition section and/or the distal transition Thick 5%-20%.
Optionally, the wall of sacculus straight portion described in the wall ratio of the Proximal transition section and/or the distal transition Thickness 1%-30%.
Optionally, the wall of sacculus straight portion described in the wall ratio of the Proximal transition section and/or the distal transition Thickness 5%-20%.
Optionally, the outer diameter of the Proximal transition section and/or the distal transition is less than the sacculus straight portion Outer diameter forms proximal end step and/or distal end step.
Optionally, the radial height of the proximal end step and/or distal end step is 0.2mm-3.0mm, and axial length is 0.5mm-3.0mm。
Optionally, the angle between the nearly tapering and Proximal transition section and/or the remote tapering and distal transition it Between angle be 90 ° -175 °.
Optionally, the axial length in the nearly tapering and/or the remote tapering is 1mm-5mm.
Optionally, the sacculus straight portion is one or more layers structure.
Optionally, each layer of material of the sacculus straight portion be thermoplastic polyurethane elastomer rubber, nylon, One or more of polyethylene, nylon elastomer are blended.
Optionally, a diameter of 1.0mm-30.0mm after the sacculus straight portion expands.
Optionally, the length of the nearly pipe end and/or the remote pipe end is 2mm-6mm.
Correspondingly, the present invention also provides a kind of stent delivery systems, including:The connector that is sequentially connected, nearly outer tube, connection Pipe, far ultraviolet pipe, sacculus, holder and the inner tube positioned at the far ultraviolet pipe and the balloon interior, using above-mentioned sacculus, the branch Set up the outside for being placed in the sacculus.
Optionally, the length of the sacculus straight portion be more than the holder length, and the Proximal transition section and/or The wall thickness of the distal transition is more than the wall thickness of the sacculus straight portion.
Optionally, the length of the sacculus straight portion be less than the holder length, and the Proximal transition section and/or The wall thickness of the distal transition is less than the wall thickness of the sacculus straight portion.
Optionally, it is located at development there are two settings at the both ends for corresponding to the sacculus straight portion on the outer wall of said inner tube Ring or development point.
Optionally, the developing ring or development point use roentgenopaque developing material.
Proximal transition section and/or distal transition is respectively set at sacculus straight portion both ends in sacculus provided by the invention, By selecting the relative length between sacculus straight portion and holder, and corresponding Proximal transition section and/or distal transition With the relative wall thickness between sacculus straight portion, the length after control stenter to implant may be implemented, while preventing the dog bone of sacculus The phenomenon that head or holder expand not open.
Description of the drawings
Fig. 1 is the structural schematic diagram of sacculus in the present invention;
Fig. 2 is the schematic diagram of stent delivery system in an embodiment in the present invention;
Fig. 3 is the structural schematic diagram after sacculus expands in an embodiment in the present invention;
Fig. 4 is the schematic diagram of stent delivery system in another embodiment in the present invention;
Fig. 5 be another embodiment of the present invention in sacculus expand after structural schematic diagram.
Specific implementation mode
The sacculus and stent delivery system of the present invention are described in more detail below in conjunction with schematic diagram, wherein table Showing the preferred embodiment of the present invention, it should be appreciated that those skilled in the art can change invention described herein, and still Realize the advantageous effects of the present invention.Therefore, following description should be understood as the widely known of those skilled in the art, and It is not intended as limitation of the present invention.
Core of the invention thought is, Proximal transition section and/or distal end is respectively set at the both ends of sacculus straight portion Changeover portion, by selecting the relative length between sacculus straight portion and holder, and corresponding Proximal transition section and/or distal end The relativeness of the wall thickness of changeover portion and the wall thickness of sacculus straight portion prevents dog bone or holder when implantation holder from expanding not open The phenomenon that.In the present invention, it may be implemented to control the length after stenter to implant under conditions of not changing holder original size.
Below in conjunction with Fig. 1-Fig. 5 to the sacculus of the present invention and being specifically described for stent delivery system.
Refering to what is shown in Fig. 1, sacculus 10 is flat including nearly pipe end 11, nearly tapering 12, Proximal transition section 13, the sacculus being sequentially connected Straight part 14, distal transition 15, remote tapering 16 and remote pipe end 17.
In the present invention, the sacculus straight portion 14 can be one or more layers structure.Also, the sacculus flat part It can be in thermoplastic polyurethane elastomer rubber, nylon, polyethylene, nylon elastomer to divide the material of 14 each layer of structure One or more are blended.The sacculus straight portion 14 expand after a diameter of 1.0mm-30.0mm.In the present embodiment, described The length of sacculus straight portion 14 is that the length for the holder being implanted into according to needs is set, for example, can be according to diseased region Length and difference between the holder of implantation selected, when the length of diseased region is longer than the length of useable holder When, sacculus straight portion 14 is shorter than holder, when the length for being shorter in length than useable holder of diseased region, sacculus straight portion 14 It is longer than holder.Therefore, different sacculus is selected, by controlling the relative length between sacculus straight portion 14 and holder so that Holder can extend or shorten, to control the length after stenter to implant.It should be noted that holder in the present invention can be with For sacculus conveying type holder, structure can be tubulose, netted, winding shape etc., and the length of holder is along sacculus straight portion 14 The length in direction, what this was appreciated that for those skilled in the art, this will not be repeated here.
In the present embodiment, sacculus 10 is integrally formed, but in preparation process so that the Proximal transition section 13 Wall thickness it is different from the wall thickness of the sacculus straight portion 14, also, sacculus described in the wall ratio of the Proximal transition section 13 is flat The wall thickness thickness of straight part 14 or thin 1%-30%, it is preferred that sacculus flat part described in the wall ratio of the Proximal transition section 13 Divide 14 wall thickness thick or thin 5%-20%.The outer diameter of the Proximal transition section 13 is less than the outer of the sacculus straight portion 14 Diameter forms proximal end step, and the radial height of the proximal end step 13 is 0.2mm-3.0mm, axial length 0.5mm-3.0mm. Meanwhile the wall thickness of the distal transition 15 is different from the wall thickness of the sacculus straight portion 14, the distal transition 15 The wall thickness thickness of sacculus straight portion 14 described in wall ratio or thin 1%-30%, it is preferred that the wall thickness of the distal transition 15 Thicker than the wall thickness of the sacculus straight portion 14 or thin 5%-20%.The outer diameter of the distal transition 15 is less than the sacculus The outer diameter of straight portion 14 forms distal end step, and the radial height of the distal end step 15 is 0.2mm-3.0mm, and length is 0.5mm-3.0mm.In the present invention, by adjusting 13 wall thickness of Proximal transition section and 14 wall thickness of sacculus straight portion The relativeness of relativeness and 15 wall thickness of the distal transition and 14 wall thickness of sacculus straight portion, can be in ball During capsule 10 is expanded, pulling force or pressure are generated at the both ends of holder, control the length of balloon expandable after-poppet, and Can preventing stent system from expanding in the process, there is a phenomenon where dog bones or holder to expand not open.
In the present invention, Proximal transition section 13 and/or distal transition 15 are not limited to form proximal end step and/or distant station Rank, as long as the other shapes of generation pulling force or pressure at holder both ends may be implemented, for example, ramped shaped etc., this is also at this Within the thought range for inventing protection.
In addition, in the present embodiment, the included angle A between the nearly tapering 12 and the Proximal transition section 13 is 90 ° -175 °, The axial length in the nearly tapering 12 is 1mm-5mm, and the length of the nearly pipe end 11 is 2mm-6mm.The remote tapering 16 and institute It is 90 ° -175 ° to state the included angle B between distal transition 15, and the axial length in the remote tapering 16 is 1mm-5mm.The remote pipe The length at end 17 is 2mm-6mm.It should be noted that the length of various pieces is controlled according to stent length in sacculus 10 The setting that actual needs carries out can preferably realize technique effect within this range.However, those skilled in the art can With understanding, the present invention should be not limited.
It should be noted that in the present invention, 10 structure of sacculus can also only include proximal end step 13 or distal end step 15, As long as the length after control stenter to implant may be implemented, the present invention is without limitation.In addition, " remote " " close " in the present invention is Distance during implantation holder apart from observer position, this is expressed as the statement observed convenient for observer, the present invention It should be not limited.
Correspondingly, the present invention also provides a kind of stent delivery system, refering to what is shown in Fig. 2, stent delivery system 40 include according to Secondary connected connector 20, nearly outer tube 30, connecting tube 50, far ultraviolet pipe 60,10 holder 80 of sacculus and be located at the far ultraviolet pipe 60 With the inner tube 70 inside the sacculus 10.In the present embodiment, technique is held by holder 80 and stent delivery system by holder pressure 40 connections so that holder 80 is set to the outside of the sacculus straight portion 14, and holder 80 at tubulose or can be wrapped in sacculus 10 outside.
Stent delivery system 40 can be divided into front and rear, and front includes inner tube 70, sacculus 10, far ultraviolet pipe 60 and connecting tube 50, rear portion includes connector 20, nearly outer tube 30, it is to be understood that during being implanted into holder 80, human body group is inserted into front It knits, therefore, front needs medical high score not reacting using and artificial skin nontoxic to human body, falling off without particle Sub- material manufacture.In the front of stent delivery system, guidewire lumen is formed in inner tube 70.So that inner tube 70,60 and of far ultraviolet pipe The assembling of connecting tube 50 forms coaxial double cavity structure, and the inside of inner tube 70 defines inner cavity, inner tube 70 and far ultraviolet pipe 60 and sacculus 10 define that exocoel, inner cavity and exocoel are used as guidewire lumen and fluid-through chamber, guidewire port formed between connecting tube 50 and inner tube 70 respectively, It is passed through seal wire along guidewire port so that the front of stent delivery system can be slided along the seal wire of inner cavity, connecting tube 50 and exocoel Part connection, for being subsequently filled with contrast solution.
In addition, it is also embedding there are two development point 71 at the both ends that are located at below sacculus straight portion 14 of outer wall of inner tube 70, The material of development point 71 uses roentgenopaque platinum or the material manufacture with developing property, during being implanted into holder 80, Development 71 position and the length for identifying sacculus 10 of point.The rear portion of stent delivery system 40 is by single-chamber stainless steel metal skeleton system At connector 20 injects contrast solution for emptying or 10 connector of Filled Balloon when being expanded for sacculus 10, nearly outer tube 30 is used for Sacculus 10 and holder 80 are sent into lesion locations.
Preferably, nearly outer tube 30 is embedded there are two label band 31, the opposite position for marking sacculus 10 and 70 top of inner tube It sets, doctor is facilitated to judge that 10 holder 80 of sacculus enters position and the distance of human body.
In conjunction with shown in Fig. 2 and Fig. 4, during being implanted into holder 80, using lancet puncture artery, arterial sheath is placed Pipe send a guiding catheter to enter lesion vessels, a seal wire is entered blood by guiding catheter after radiography by Arterial sheath The front of pipe distal end, sacculus 10 and stent delivery system 40 is slided along seal wire hence into human body together, at this point it is possible to logical The rough position for judging sacculus 10 and entering human body of label band 31 is crossed, passes through the rear portion of stent delivery system (connector 20, closely later Outer tube 30) exocoel anteriorly conveys contrast solution, and then by the point 71 that develops accurately judge sacculus 10 in the position of human body and The length of sacculus 10, and sacculus 10 is expanded, to which holder 80 is implanted into human body.Later, radiography is emptied by connector 20 Liquid so that sacculus 10 is shunk, and sacculus 10 is taken out, to which holder 80 is implanted into human body.
Sacculus 10 expand after structural reference Fig. 3 shown in, in the present embodiment, the wall thickness of the Proximal transition section 13 of sacculus 10 With the wall thickness thickness 20% of the wall ratio sacculus straight portion 14 of distal transition 15.Length is 13.0mm, ball before holder 80 extends Balloon diameter is 3.50mm after capsule 10 is expanded, and the length of sacculus straight portion 14 is 14.0mm, Proximal transition section (proximal end step) 13 and distal transition (distal end step) 15 height be 1.0mm, Proximal transition section 13 and 15 length of distal transition are 2.0mm, the angle A between Proximal transition section 13 and nearly tapering 12 are 160 °, the angle between distal transition 15 and remote tapering 16 It is 160 ° to spend B, and the length in nearly tapering 12 and remote tapering 16 is 3mm, and the length of nearly pipe end 11 and remote pipeline section 17 is 3mm.Due to ball The length of capsule straight portion 14 is longer than the length of holder 80, and the wall of the Proximal transition section 13 and distal transition 15 of sacculus 10 The wall thickness of thickness rate sacculus straight portion 14 is thick, and when sacculus 10 has expanded holder 80, Proximal transition section 13 and distal transition 15 can be with By holder 80 to intermediate compression, the generation of dog bone phenomenon on the one hand can be prevented, on the other hand so that branch after expansion 80 length of frame is 8.5mm so that holder 80 shortens relative to original size, to realize the length after the control implantation of holder 80. It therefore, can be by controlling relative length and Proximal transition between sacculus straight portion 14 and holder 80 in the present embodiment The relativeness of section 13 and distal transition 15 and the thickness of sacculus straight portion 14, i.e.,:When the length of sacculus straight portion 14 More than holder 80 length when, the wall thickness of Proximal transition section 13 and/or distal transition 15 is more than the wall of sacculus straight portion 14 Thickness realizes that under conditions of need not adjust 80 size of holder, the length after control holder 80 is implanted into contracts relative to original size It is short.
Another embodiment of the stent delivery system 40 of the present invention is refering to what is shown in Fig. 4, in the present embodiment, use is identical Holder 80 is arranged in the outside of sacculus 10 process, also, holder 80 is implanted into the lesion of human body using identical method Position, details are not described herein.The present embodiment and previous embodiment difference lies in, after sacculus 10 is expanded, 13 He of Proximal transition section Distal transition 15 is located at the inside of holder 80, and the structure chart after the expansion of sacculus 10 is with reference to shown in figure 5.In the present embodiment, ball The wall thickness of the Proximal transition section 13 of capsule 10 and the wall ratio sacculus straight portion 14 of distal transition 15 is thin by 5%, the original of holder 80 Beginning length is 33.0mm, and balloon diameter is 4.00mm after sacculus 10 is expanded, and the length of sacculus straight portion 14 is 32.5mm, proximal end The height of changeover portion (proximal end step) 13 and distal transition (distal end step) 15 is 1.2mm, Proximal transition section 13 and distal end mistake It is 2.2mm to cross 15 length of section, and the angle A between Proximal transition section 13 and nearly tapering 12 is 150 °, distal transition 15 and remote cone Angle B between portion 16 is 150 °, and the length in nearly tapering 12 and remote tapering 16 is 3.5mm, the length of nearly pipe end 11 and remote pipeline section 17 Degree is 3.5mm.80 length of holder, also, 13 He of Proximal transition section of sacculus 10 are shorter in length than due to sacculus straight portion 10 The wall of distal transition 15 is thinner than the wall of sacculus straight portion 14, when sacculus 10 has expanded holder 80 so that 13 He of Proximal transition section Distal transition 15 can stretch holder 80 to both ends, on the one hand can prevent holder 80 from can not expand the generation of phenomenon, another Aspect so that 80 length of holder after expansion is 35.5mm, i.e., when the length of sacculus straight portion 14 is less than the length of holder 80 When, the wall thickness of Proximal transition section 13 and/or distal transition 15 is less than the wall thickness of sacculus straight portion 14, so that holder 80 It is extended relative to original size, realizes the length after control holder 80 is implanted into.
In conclusion provided by the invention be respectively set Proximal transition section and/or distal end mistake at sacculus straight portion both ends Section is crossed, by controlling the relative length between sacculus straight portion and holder, to control the length after stenter to implant.Also, By controlling the relativeness of the wall thickness of the wall thickness and sacculus straight portion of Proximal transition section and/or distal transition, ball is prevented Capsule expand during dog bone or holder the phenomenon that expanding not open.In the present invention, it may be implemented do not changing holder original size Under conditions of control stenter to implant after length.
Obviously, various changes and modifications can be made to the invention without departing from essence of the invention by those skilled in the art God and range.In this way, if these modifications and changes of the present invention belongs to the range of the claims in the present invention and its equivalent technologies Within, then the present invention is also intended to include these modifications and variations.

Claims (15)

1. a kind of sacculus, including the nearly pipe end, nearly tapering, sacculus straight portion, remote tapering and the remote pipe end that are sequentially connected, it is special Sign is, further includes Proximal transition section and/or distal transition, and the Proximal transition section connects the nearly tapering and the sacculus Straight portion, the distal transition connect the sacculus straight portion and the remote tapering, and the Proximal transition section and/or The wall thickness of the distal transition is different from the wall thickness of sacculus straight portion, wherein the Proximal transition section and/or described The thin 1%-30% of the wall thickness of sacculus straight portion described in the wall ratio of distal transition.
2. sacculus as described in claim 1, which is characterized in that the wall of the Proximal transition section and/or the distal transition The thin 5%-20% of the wall thickness of sacculus straight portion described in thickness rate.
3. sacculus as described in claim 1, which is characterized in that the Proximal transition section and/or the distal transition it is outer Diameter is less than the outer diameter of the sacculus straight portion, forms proximal end step and/or distal end step.
4. sacculus as claimed in claim 3, which is characterized in that the radial height of the proximal end step and/or distal end step is 0.2mm-3.0mm, axial length 0.5mm-3.0mm.
5. sacculus according to any one of claims 1-4, which is characterized in that the folder between the nearly tapering and Proximal transition section Angle between angle and/or the remote tapering and distal transition is 90 ° -175 °.
6. sacculus according to any one of claims 1-4, which is characterized in that the axis in the nearly tapering and/or the remote tapering It is 1mm-5mm to length.
7. sacculus according to any one of claims 1-4, which is characterized in that the sacculus straight portion is tied for one or more layers Structure.
8. sacculus as claimed in claim 7, which is characterized in that each layer of material of the sacculus straight portion is thermoplastic Property elastic polyurethane body rubber, nylon, polyethylene, one or more of nylon elastomer be blended.
9. sacculus according to any one of claims 1-4, which is characterized in that the sacculus straight portion expand after it is a diameter of 1.0mm-30.0mm。
10. sacculus according to any one of claims 1-4, which is characterized in that the length of the nearly pipe end and/or the remote pipe end Degree is 2mm-6mm.
11. a kind of stent delivery system, including:Connector, nearly outer tube, connecting tube, far ultraviolet pipe, the sacculus being sequentially connected, holder And the inner tube positioned at the far ultraviolet pipe and the balloon interior, which is characterized in that the sacculus uses such as claim 1-10 Any one of described in sacculus, the holder is set to the outside of the sacculus.
12. stent delivery system as claimed in claim 11, which is characterized in that the length of the sacculus straight portion is more than institute The length of holder is stated, and the wall thickness of the Proximal transition section and/or the distal transition is more than the sacculus straight portion Wall thickness.
13. stent delivery system as claimed in claim 11, which is characterized in that the length of the sacculus straight portion is less than institute The length of holder is stated, and the wall thickness of the Proximal transition section and/or the distal transition is less than the sacculus straight portion Wall thickness.
14. stent delivery system as claimed in claim 11, which is characterized in that be located on the outer wall of said inner tube described in corresponding to There are two developing ring or development points for setting at the both ends of sacculus straight portion.
15. stent delivery system as claimed in claim 14, which is characterized in that the developing ring or development point use impermeable X The developing material of ray.
CN201510154990.9A 2015-04-02 2015-04-02 Sacculus and stent delivery system Active CN106137485B (en)

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CN112494785A (en) * 2020-12-03 2021-03-16 广东博迈医疗器械有限公司 Balloon catheter with novel structure

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CN1864761A (en) * 2006-04-13 2006-11-22 大连大学医学院生物医学研究所 Balloon catheter mold
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