CN106119086A - A kind of automatic mixing extraction apparatus - Google Patents
A kind of automatic mixing extraction apparatus Download PDFInfo
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- CN106119086A CN106119086A CN201610712565.1A CN201610712565A CN106119086A CN 106119086 A CN106119086 A CN 106119086A CN 201610712565 A CN201610712565 A CN 201610712565A CN 106119086 A CN106119086 A CN 106119086A
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- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
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Abstract
The invention provides a kind of automatic mixing extraction apparatus, belong to experiment instrument field, including centrifuge tube, frame, installing mechanism, rotating mechanism and automatic feed liquor mechanism, rotating mechanism and automatic feed liquor mechanism are separately mounted in frame, rotating mechanism drive connection installing mechanism, centrifuge tube is arranged on installing mechanism, and automatic feed liquor mechanism is for putting into liquid in centrifuge tube.The automatic mixing extraction apparatus that the present invention provides can realize automatization completely, after centrifuge tube is installed on installing mechanism, installing mechanism is driven to rotate by rotating mechanism, realize the variation of centrifuge tube station, be more once pointed to centrifuge tube below by automatic feed liquor mechanism and carry out liquid feeding and take liquid, finally driven installing mechanism to rotate by rotating mechanism, realize shaking up of centrifugal liquid in pipe, this process operation is simple, and is shaken up by machinery, and the uniformity coefficient of liquid is higher.
Description
Technical field
The present invention relates to test instrument field, in particular to a kind of automatic mixing extraction apparatus.
Background technology
The biomacromolecule compound that acid is become by many nucleotide polymerization, for one of the most basic material of life.Nucleic acid is wide
General be present in all animal and plant cellss, microbial body, the nucleic acid in organism often with protein bound formation nucleoprotein.Different
Nucleic acid, its difference such as chemical composition, nucleotidesequence, the mixing of current instrument for extracting nucleic acid reactant liquor be with bar magnet and
Bar magnet set.When needs mix, bar magnet removes from bar magnet overlaps, and is enclosed within vertical tremor or rotation in reaction liquid by bar magnet
Mixing reactant liquor, reactant liquor to be contained in test box or deep-well plates in advance.
Inventor finds under study for action, and existing extraction apparatus at least has the disadvantage in that the test box of existing extraction apparatus
Or deep-well plates reactant liquor to be pre-installed, troublesome poeration, and stir uneven when operation.
Summary of the invention
It is an object of the invention to provide a kind of automatic mixing extraction apparatus, to improve existing extraction apparatus troublesome poeration and stirring
Uneven problem.
The present invention is achieved in that
Based on above-mentioned purpose, the invention provides a kind of automatic mixing extraction apparatus, including centrifuge tube, frame, installing mechanism,
Rotating mechanism and automatic feed liquor mechanism, described rotating mechanism and described automatic feed liquor mechanism are separately mounted in described frame, institute
Stating installing mechanism described in rotating mechanism drive connection, described centrifuge tube is arranged on described installing mechanism, described automatic liquid filling machine
Structure is for putting into liquid in described centrifuge tube.
The automatic mixing extraction apparatus that the present invention provides can realize automatization completely, and centrifuge tube is installed to installing mechanism
After on, rotating mechanism installing mechanism is driven to rotate, it is achieved the variation of centrifuge tube station, then by the para-position of automatic feed liquor mechanism
Carry out liquid feeding in centrifuge tube below and take liquid, finally being driven installing mechanism to rotate by rotating mechanism, it is achieved centrifugal intraluminal fluid
Shaking up of body, this process operation is simple, and is shaken up by machinery, and the uniformity coefficient of liquid is higher.
Further, described installing mechanism includes centrifuge tube dish, gland dish and for fixing the control dish of described centrifuge tube,
Described centrifuge tube dish is installed on the outfan of described rotating mechanism, and described centrifuge tube dish is provided with multiple through hole, described through hole
Axial line vertical with the surface of described centrifuge tube dish, multiple described through hole being provided at circumferentially spaced along described centrifuge tube dish, institute
State control dish to be arranged on described centrifuge tube dish, and described control dish is coaxial with described centrifuge tube dish；Described centrifuge tube includes pipe
Body, connector and lid, described body is arranged in described through hole, and described lid is by described connector with described body even
Connecing, described connector is connected in described control dish；Described gland dish is arranged on described control dish, and described control dish is positioned at described
Between gland dish and described centrifuge tube dish, described gland dish is for controlling the open angle of described lid.
Gland dish controls lid and is maintained at a relative suitably angle with body, make lid and body have enough away from
From, this time, the work of automatic feed liquor mechanism was unaffected, and meanwhile, lid also will not be too remote apart from body, is closing
During lid the most very convenient.
Further, the edge of described control dish being provided with multiple breach, described breach is along the radial direction of described control dish
Cave inward, multiple described breach being provided at circumferentially spaced along described control dish, and the position pair of described breach and described through hole
Should, described connector is connected in described breach.
Connector is connected in breach, shackle member can be avoided to rotate along the direction of axis line of centrifuge tube, can make clamping
Part remains in the same direction, so the enhanced convenience when opening and closing lid.
Further, described connector includes the first contiguous block and the second contiguous block, described first contiguous block and described pipe
Body connects, and described second contiguous block is connected with described lid, and described first contiguous block is rotationally connected with described second contiguous block, institute
Stating second contiguous block radial rotating along described first contiguous block, the junction of the first contiguous block and described second contiguous block is positioned at
In described breach.
First contiguous block and the second contiguous block are when relatively rotating, and in an angle, this angle is along centrifuge tube dish for meeting shape
Radial direction direct at the center of centrifuge tube dish, the opening that therefore the first contiguous block and the second contiguous block are formed is the footpath along centrifuge tube dish
To outside, the enhanced convenience when opening and closing.
Further, described connector also includes the back-moving spring in compressive state, and one end of described back-moving spring is installed
On described first contiguous block, the other end of described back-moving spring is arranged on described second contiguous block, and described back-moving spring makes
Described second contiguous block has the trend away from described first contiguous block.
It is connected on centrifuge tube due to lid at ordinary times, together with the first contiguous block is positioned against with the second contiguous block, when uncapping
After lid is opened by mechanism, the second contiguous block, under the effect of back-moving spring, is opened to maximum, i.e. second contiguous block arrive with
The position of gland dish contact, so can avoid lid to open insufficient, thus ensure being normally carried out of subsequent step.
Further, described automatic feed liquor mechanism includes cap-opening mechanism, liquid sucting mechanism, mechanism for filling liquid and pass lid mechanism, institute
State cap-opening mechanism, described liquid sucting mechanism, described mechanism for filling liquid and described pass lid mechanism to be separately mounted in described frame, described in open
Lid mechanism, described liquid sucting mechanism, described mechanism for filling liquid and described pass lid mechanism being provided at circumferentially spaced along described centrifuge tube dish.
Centrifuge tube, in rotation process, can be delivered to below the outfan of automatic feed liquor mechanism, by the machine of uncapping by installing mechanism
Lid is opened by structure, and after lid is opened, the first contiguous block and the second contiguous block are at an angle, and centrifuge tube is with installing mechanism
Go to next station and carry out taking liquid and liquid feeding, lid is shut by closing lid mechanism the most again, during secondary, extraction apparatus each
Individual mechanism works continuously, can improve work efficiency greatly.
Further, described cap-opening mechanism includes the first cylinder and uncaps portion, described in the portion of uncapping be installed on described first gas
The outfan of cylinder, described in the uncap direction of motion in portion parallel with the direction of axis line of described through hole, described in the portion's of uncapping motion make institute
State lid to open；Described pass lid mechanism includes the second cylinder and closes cap, and described pass cap is installed on the defeated of described second cylinder
Going out end, the direction of motion of described pass cap is parallel with the direction of axis line of described through hole, and cap motion in described pass makes described lid
Close.
The portion of uncapping starts to be positioned at the lower section of lid, and when the first cylinder operation, the portion of uncapping rises, and is backed down by lid, completes
Uncap action, then return initial position, wait that next centrifuge tube reaches this station, be then further continued for work；Close cap
Start to be positioned at the top of lid, when the second cylinder operation, close cap and decline, by cover closing, complete to close lid action, the most again
Return to initial position, wait that next centrifuge tube reaches this station, be then further continued for work.
Further, described in the portion of uncapping include head rod and the first shifting block, one end of described head rod is installed
In the outfan of described first cylinder, the axis parallel of the axial line of described head rod and described through hole, described first
Shifting block is installed on the other end of described head rod, and described first shifting block motion makes described lid open；Described pass cap bag
Including the second connecting rod and the second shifting block, the outfan with described first cylinder is installed in one end of described second connecting rod, and described the
The axial line of two connecting rods and the axis parallel of described through hole, described second shifting block is installed on another of described second connecting rod
End, described second shifting block motion makes described cover closing.
The axial line of head rod is parallel with the operative orientation of the first cylinder, and such first cylinder is the most more
Flexibly and easily；The axial line of the second connecting rod is parallel with the operative orientation of the second cylinder, and such second cylinder is the most more
Flexible.
Further, to include that the first motor and the first output shaft, described first motor are arranged on described for described rotating mechanism
In frame, described installing mechanism is connected with described first motor by described first output shaft, and described installing mechanism is along described the
The axial line of one output shaft rotates.
First output motor can drive installing mechanism to rotate, and makes centrifuge tube arrive each station by controllable rotary,
At the same time it can also be the liquid in making centrifuge tube is shaken up rapidly.
Further, described automatic mixing extraction apparatus also includes the second motor and the second output shaft, and described frame includes the end
Seat and rotation dish, described rotating mechanism is arranged on described rotation dish, and described automatic feed liquor mechanism is arranged on described base, institute
Stating the second motor to be arranged on described base, described rotation dish is connected with described second motor by described second output shaft, institute
The axial line stating the second output shaft is vertical with the axial line of described first output shaft.
Second output motor can drive turn disc, makes rotation dish rotate along the direction being perpendicular to the first output shaft,
Second output motor and the first output motor coordinate, and make that liquid shaken is the most uniform.
Compared with prior art, the present invention realizes providing the benefit that:
The automatic mixing extraction apparatus that the present invention provides can realize automatization completely, and centrifuge tube is installed to installing mechanism
After on, rotating mechanism installing mechanism is driven to rotate, it is achieved the variation of centrifuge tube station, then by the para-position of automatic feed liquor mechanism
Carry out liquid feeding in centrifuge tube below and take liquid, finally being driven installing mechanism to rotate by rotating mechanism, it is achieved centrifugal intraluminal fluid
Shaking up of body, this process operation is simple, and is shaken up by machinery, and the uniformity coefficient of liquid is higher.
Accompanying drawing explanation
Fig. 1 shows the schematic diagram automatically shaking up extraction apparatus that preferred embodiment of the present invention provides；
Fig. 2 shows the top view automatically shaking up extraction apparatus that preferred embodiment of the present invention provides；
Fig. 3 shows the schematic diagram of the first duty of installing mechanism that preferred embodiment of the present invention provides；
Fig. 4 shows the schematic diagram of installing mechanism the second duty that preferred embodiment of the present invention provides；
Fig. 5 shows the schematic diagram of the centrifuge tube dish that preferred embodiment of the present invention provides；
Fig. 6 shows the schematic diagram of the control dish that preferred embodiment of the present invention provides；
Fig. 7 shows the schematic diagram of the shrouding disc that preferred embodiment of the present invention provides；
Fig. 8 shows the schematic diagram of the connector that preferred embodiment of the present invention provides.
In figure:
Base 101；Rotation dish 102；Frame 103；Body 104；Connector 105；Lid 106；Centrifuge tube 107；Centrifuge tube
Dish 108；Control dish 109；Gland dish 110；First motor 111；First output shaft 112；Rotating mechanism 113；Second motor 114；
Second output shaft 115；First cylinder 116；Head rod 117；First shifting block 118；Uncap portion 119；Cap-opening mechanism 120；Inhale
Liquid mechanism 121；Mechanism for filling liquid 122；Close lid mechanism 123；Through hole 124；Breach 125；First contiguous block 126；Second contiguous block
127；Back-moving spring 128.
Detailed description of the invention
The biomacromolecule compound that acid is become by many nucleotide polymerization, for one of the most basic material of life.Nucleic acid is wide
General be present in all animal and plant cellss, microbial body, the nucleic acid in organism often with protein bound formation nucleoprotein.Different
Nucleic acid, its difference such as chemical composition, nucleotidesequence, the mixing of current instrument for extracting nucleic acid reactant liquor be with bar magnet and
Bar magnet set.When needs mix, bar magnet removes from bar magnet overlaps, and is enclosed within vertical tremor or rotation in reaction liquid by bar magnet
Mixing reactant liquor, reactant liquor to be contained in test box or deep-well plates in advance.Inventor finds under study for action, existing extraction apparatus
At least have the disadvantage in that test box or the deep-well plates reactant liquor to be pre-installed of existing extraction apparatus, troublesome poeration, and operating
Time stir uneven.
In order to make the problems referred to above be improved, the invention provides a kind of automatic mixing extraction apparatus, including centrifuge tube, machine
Frame, installing mechanism, rotating mechanism and automatic feed liquor mechanism, described rotating mechanism and described automatic feed liquor mechanism are separately mounted to institute
Stating in frame, installing mechanism described in described rotating mechanism drive connection, described centrifuge tube is arranged on described installing mechanism, described
Automatically feed liquor mechanism is for putting into liquid in described centrifuge tube.
The automatic mixing extraction apparatus that the present invention provides can realize automatization completely, and centrifuge tube is installed to installing mechanism
After on, rotating mechanism installing mechanism is driven to rotate, it is achieved the variation of centrifuge tube station, then by the para-position of automatic feed liquor mechanism
Carry out liquid feeding in centrifuge tube below and take liquid, finally being driven installing mechanism to rotate by rotating mechanism, it is achieved centrifugal intraluminal fluid
Shaking up of body, this process operation is simple, and is shaken up by machinery, and the uniformity coefficient of liquid is higher.
Below by specific embodiment and combine accompanying drawing the present invention is described in further detail.
For making the purpose of the embodiment of the present invention, technical scheme and advantage clearer, above in conjunction with in the embodiment of the present invention
Accompanying drawing, carried out clearly and completely describing to the technical scheme in the embodiment of the present invention, it is clear that described embodiment is
The a part of embodiment of the present invention rather than whole embodiments.Generally implement with the present invention illustrated described in accompanying drawing herein
The assembly of example can be arranged with various different configurations and design.
Therefore, the detailed description of the above embodiments of the invention to providing in the accompanying drawings is not intended to limit claimed
The scope of the present invention, but be merely representative of the selected embodiment of the present invention.Based on the embodiment in the present invention, this area is common
The every other embodiment that technical staff is obtained under not making creative work premise, broadly falls into the model of present invention protection
Enclose.
It should also be noted that similar label and letter represent similar terms, therefore, the most a certain Xiang Yi in following accompanying drawing
Individual accompanying drawing is defined, then need not it be defined further and explains in accompanying drawing subsequently.
In describing the invention, it should be noted that term " " center ", " on ", D score, " vertically ", " level ",
Orientation or the position relationship of the instruction such as " interior ", " outward " are based on orientation shown in the drawings or position relationship, or this invention is produced
The orientation usually put during product use or position relationship, be for only for ease of the description present invention and simplify description rather than indicate
Hint indication device or element must have specific orientation, with specific azimuth configuration and operation, be not understood that
For limitation of the present invention.Describe additionally, term " first ", " second " etc. are only used for distinguishing, and it is not intended that indicate or dark
Show relative importance.
In describing the invention, in addition it is also necessary to explanation, unless otherwise clearly defined and limited, term " arrange ",
" install ", " being connected ", " connection " should be interpreted broadly, and connect for example, it may be fixing, it is also possible to be to removably connect, or one
Body ground connects；Can be to be mechanically connected, it is also possible to be electrical connection；Can be to be joined directly together, it is also possible to indirect by intermediary
It is connected, can be the connection of two element internals.For the ordinary skill in the art, can be with in concrete condition understanding
State term concrete meaning in the present invention.
It should be noted that in the case of not conflicting, the embodiment in the present invention and the feature in embodiment can phases
Combination mutually.
Referring to figs. 1 through Fig. 2, present embodiments provide a kind of automatic mixing extraction apparatus, including centrifuge tube 107, frame 103,
Installing mechanism, rotating mechanism 113 and automatic feed liquor mechanism, rotating mechanism 113 and automatic feed liquor mechanism are separately mounted to frame 103
On, rotating mechanism 113 drive connection installing mechanism, centrifuge tube 107 is arranged on installing mechanism, and automatic feed liquor mechanism is for by liquid
Body is put in centrifuge tube 107.
The automatic mixing extraction apparatus that the present embodiment provides can realize automatization completely, is installed to by centrifuge tube 107
After on mounting mechanism, rotating mechanism 113 installing mechanism is driven to rotate, it is achieved the variation of centrifuge tube 107 station, then by automatic feed liquor
Mechanism is once pointed to centrifuge tube 107 below and carries out liquid feeding and take liquid, is finally driven installing mechanism to turn by rotating mechanism 113
Dynamic, it is achieved the shaking up of liquid in centrifuge tube 107, this process operation is simple, and is shaken up by machinery, and the uniformity coefficient of liquid is more
High.
Refering to Fig. 3 to Fig. 7, installing mechanism includes centrifuge tube dish 108, gland dish 110 and for fixing the control of centrifuge tube 107
Dish 109 processed, centrifuge tube dish 108 is installed on the outfan of rotating mechanism 113, and centrifuge tube dish 108 is provided with multiple through hole 124,
The axial line of through hole 124 is vertical with the surface of centrifuge tube dish 108, and multiple through holes 124 set along the circumferentially-spaced of centrifuge tube dish 108
Putting, control dish 109 is arranged on centrifuge tube dish 108, and control dish 109 is coaxial with centrifuge tube dish 108；Centrifuge tube 107 includes pipe
Body 104, connector 105 and lid 106, body 104 is arranged in through hole 124, and lid 106 is by connector 105 and body 104
Connecting, connector 105 is connected in control dish 109；Gland dish 110 is arranged on control dish 109, and control dish 109 is positioned at gland dish
Between 110 and centrifuge tube dish 108, gland dish 110 is for controlling the open angle of lid 106.
Gland dish 110 controls lid 106 and is maintained at a relative suitably angle with body 104, makes lid 106 and body
104 have enough distances, and this time, the work of automatic feed liquor mechanism was unaffected, and meanwhile, lid 106 also will not be away from
From body 104 too away from, close lid 106 time the most very convenient.
Refering to Fig. 6, the edge of control dish 109 is provided with multiple breach 125, breach 125 along control dish 109 radial direction to
Sunken inside, multiple breach 125 being provided at circumferentially spaced along control dish 109, and breach 125 is corresponding with the position of through hole 124, connects
Part 105 is connected in breach 125.Connector 105 is connected in breach 125, and shackle member can be avoided along the axial line of centrifuge tube 107
Direction rotates, and shackle member can be made to remain in the same direction, so when opening and closing lid 106 more
Convenience.
Connector 105 includes the first contiguous block 126 and the second contiguous block 127, and the first contiguous block 126 is connected with body 104,
Second contiguous block 127 is connected with lid 106, and the first contiguous block 126 is rotationally connected with the second contiguous block 127, the second contiguous block 127
Along the radial rotating of the first contiguous block 126, the junction of the first contiguous block 126 and the second contiguous block 127 is positioned at breach 125.
First contiguous block 126 and the second contiguous block 127 when relatively rotating, can shape in an angle, this angle along from
The radial direction of heart pipe dish 108 directs at the center of centrifuge tube dish 108, and what therefore the first contiguous block 126 and the second contiguous block 127 were formed opens
Mouthful it is radially outer along centrifuge tube dish 108, the enhanced convenience when opening and closing.
Refering to Fig. 8, connector 105 can also include a back-moving spring 128 in compressive state, back-moving spring 128
One end is arranged on the first contiguous block 126, and the other end of back-moving spring 128 is arranged on the second contiguous block 127, back-moving spring
128 make the second contiguous block 127 have the trend away from the first contiguous block 126, are connected to centrifuge tube 107 due to lid 106 at ordinary times
On, together with the first contiguous block 126 is positioned against with the second contiguous block 127, after lid 106 is opened by cap-opening mechanism 120, second
Contiguous block 127, under the effect of back-moving spring 128, is opened to maximum, and the i.e. second contiguous block 127 arrives and connects with gland dish 110
The position touched, so can avoid lid 106 to open insufficient, thus ensure being normally carried out of subsequent step.
Automatically feed liquor mechanism includes cap-opening mechanism 120, liquid sucting mechanism 121, mechanism for filling liquid 122 and closes lid mechanism 123, uncaps
Mechanism 120, liquid sucting mechanism 121, mechanism for filling liquid 122 and pass lid mechanism 123 are separately mounted in frame 103, cap-opening mechanism 120,
Liquid sucting mechanism 121, mechanism for filling liquid 122 and pass lid mechanism 123 being provided at circumferentially spaced along centrifuge tube dish 108.
Centrifuge tube 107, in rotation process, can be delivered to below the outfan of automatic feed liquor mechanism, by uncapping by installing mechanism
Lid 106 is opened by mechanism 120, and after lid 106 is opened, the first contiguous block 126 and the second contiguous block 127 are in certain angle
Degree, centrifuge tube 107 goes to next station with installing mechanism and carries out taking liquid and liquid feeding, the most again by closing lid mechanism 123 by lid
106 shut, and during secondary, each mechanism of extraction apparatus works continuously, can improve work efficiency greatly.
Wherein, liquid sucting mechanism 121 and mechanism for filling liquid 122 may be located on same station, and centrifuge tube 107 arrives presets station
After, the outfan of liquid sucting mechanism 121 and the outfan of mechanism for filling liquid 122 go deep in centrifuge tube 107 simultaneously, and liquid sucting mechanism 121 is first
Work is by the liquid sucking-off in centrifuge tube 107, then is injected liquid in centrifuge tube 107 by mechanism for filling liquid 122.
Cap-opening mechanism 120 includes the first cylinder 116 and the portion 119 that uncaps, and the portion 119 that uncaps is installed on the defeated of the first cylinder 116
Going out end, the direction of motion in the portion 119 that uncaps is parallel with the direction of axis line of through hole 124, and portion 119 motion of uncapping makes lid 106 open；
Close lid mechanism 123 include the second cylinder and close cap, close cap and be installed on the outfan of the second cylinder, close the direction of motion of cap
Parallel with the direction of axis line of through hole 124, close cap motion and make lid 106 close.
The portion 119 that uncaps starts to be positioned at the lower section of lid 106, and when the first cylinder 116 works, the portion 119 that uncaps rises, will lid
Son 106 backs down, and completes action of uncapping, and then returns initial position, waits that next centrifuge tube 107 reaches this station, then
It is further continued for work；Close cap and start to be positioned at the top of lid 106, when the second cylinder operation, close cap and decline, by lid 106
Close, complete to close lid action, then return initial position, wait that next centrifuge tube 107 reaches this station, be then further continued for
Work.
The portion 119 that uncaps includes head rod 117 and the first shifting block 118, and one end of head rod 117 is installed on first
The axis parallel of the outfan of cylinder 116, the axial line of head rod 117 and through hole 124, the first shifting block 118 is installed on
The other end of head rod 117, the first shifting block 118 motion makes lid 106 open；Close cap and include the second connecting rod and second
Shifting block, the outfan with the first cylinder 116, the axial line of the second connecting rod and through hole 124 are installed in one end of the second connecting rod
Axis parallel, the second shifting block is installed on the other end of the second connecting rod, and the second shifting block motion makes lid 106 close.
The axial line of head rod 117 is parallel with the operative orientation of the first cylinder 116, and such first cylinder 116 is in work
When making the most flexible；The axial line of the second connecting rod is parallel with the operative orientation of the second cylinder, and such second cylinder exists
During work the most flexible.
Rotating mechanism 113 includes the first motor 111 and the first output shaft 112, and the first motor 111 is arranged in frame 103,
Installing mechanism is connected with the first motor 111 by the first output shaft 112, and installing mechanism turns along the axial line of the first output shaft 112
Dynamic.First output motor can drive installing mechanism to rotate, and makes centrifuge tube 107 arrive each station by controllable rotary, with
Time, it is also possible to make the liquid in centrifuge tube 107 be shaken up rapidly.
Automatic mixing extraction apparatus also includes the second motor 114 and the second output shaft 115 axle, and frame 103 includes base 101 He
Rotation dish 102, rotating mechanism 113 is arranged on rotation dish 102, and automatic feed liquor mechanism is arranged on base 101, the second motor
114 are arranged on base 101, and rotation dish 102 is connected by the second output shaft 115 axle and the second motor 114, the second output shaft
The axial line of 115 axles is vertical with the axial line of the first output shaft 112.
Second output shaft 115 motor can drive rotation dish 102 to rotate, and makes rotation dish 102 along being perpendicular to the first output shaft
The direction of 112 rotates, the second output shaft 115 motor and the cooperation of the first output motor, and make that liquid shaken is the most uniform.
The automatic mixing extraction apparatus that the present embodiment provides, before work, first all puts into centrifuge tube in each through hole 124
107, allow the connector 105 of centrifuge tube 107 be stuck in breach 125；
The most automatically shake up extraction apparatus to start working, first driven centrifuge tube dish 108 to rotate by the first motor 111, control
Dish 109 and gland dish 110 and centrifuge tube dish 108 synchronous axial system, when after the station that centrifuge tube 107 reaches default, the first motor 111
Quit work；
Now the first cylinder 116 works, and makes the portion of uncapping 119 move upward, the portion 119 that uncaps during moving upward,
First shifting block 118 contacts with the second contiguous block 127 and drives the second contiguous block 127 to be rotated up, and makes lid 106 and body 104
Departing from, after lid 106 departs from body 104, it is straight that the second contiguous block 127 continues up rotation under the effect of back-moving spring 128
To contacting with cover clamp, meanwhile, the first cylinder 116 drives the portion 119 that uncaps to return to initial position；
First motor 111 task again, drives centrifuge tube 107 to turn to next station and stopping, now, existing washing liquid
Liquid, then imbibition, by the liquid sucking-off in centrifuge tube 107, are injected by mechanism for filling liquid 122 the most again in centrifuge tube 107 by mechanism
Mechanism 121 and mechanism for filling liquid 122 all leave centrifuge tube 107；
First motor 111 works on, and drives centrifuge tube 107 to reach next work for then to stop, now the second cylinder
Work, the second cylinder drives pass cap to move downward, and the second shifting block contacts with the second contiguous block 127 during declining, and
Driving the second contiguous block 127 to rotate down, and finally make lid 106 be connected together with body 104, now the second cylinder drives
Lid portion returns to initial position and quits work；
Between cap-opening mechanism 120, liquid sucting mechanism 121, mechanism for filling liquid 122 and the distance and the through hole 124 that close lid mechanism 123
Spacing distance is identical, therefore, when the first motor 111 drives centrifuge tube dish 108 to rotate, cap-opening mechanism 120, liquid sucting mechanism 121,
Mechanism for filling liquid 122 and pass lid mechanism 123 carry out continuous print work, after centrifuge tube dish 108 rotates one week, complete fluid injection action,
Now the second motor 114 drives rotation dish 102 to rotate in perpendicular, and the first motor 111 drives centrifuge tube dish 108 along first
The axial line of rotary shaft rotates, and the first motor 111 coordinates with the second motor 114 and shakes up centrifuge tube 107；
After having shaken up, rotation dish 102 returns to initial position, continues above-mentioned action, and wherein liquid sucting mechanism 121 is exactly will
The liquid shaken up takes out, and mechanism for filling liquid 122 is to be put in centrifuge tube 107 by the liquid proportional for shaking up.
In sum, the automatic mixing extraction apparatus that the present invention provides can realize automatization completely, is installed by centrifuge tube
After on installing mechanism, rotating mechanism installing mechanism is driven to rotate, it is achieved the variation of centrifuge tube station, then by automatic liquid filling machine
Structure is once pointed to centrifuge tube below to carry out liquid feeding and takes liquid, is finally driven installing mechanism to rotate by rotating mechanism, it is achieved
Shaking up of centrifugal liquid in pipe, this process operation is simple, and is shaken up by machinery, and the uniformity coefficient of liquid is higher.
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, for the skill of this area
For art personnel, the present invention can have various modifications and variations.All within the spirit and principles in the present invention, that is made any repaiies
Change, equivalent, improvement etc., should be included within the scope of the present invention.
Claims (10)
1. an automatic mixing extraction apparatus, it is characterised in that include centrifuge tube, frame, installing mechanism, rotating mechanism and automatically enter
Liquid mechanism, described rotating mechanism and described automatic feed liquor mechanism are separately mounted in described frame, and described rotating mechanism drives even
Connecing described installing mechanism, described centrifuge tube is arranged on described installing mechanism, and described automatic feed liquor mechanism is for putting into liquid
In described centrifuge tube.
Automatic mixing extraction apparatus the most according to claim 1, it is characterised in that described installing mechanism include centrifuge tube dish,
Gland dish and for fixing the control dish of described centrifuge tube, described centrifuge tube dish is installed on the outfan of described rotating mechanism, institute
Stating and be provided with multiple through hole on centrifuge tube dish, the axial line of described through hole is vertical with the surface of described centrifuge tube dish, multiple described
Through hole is provided at circumferentially spaced along described centrifuge tube dish, and described control dish is arranged on described centrifuge tube dish, and described control dish
Coaxial with described centrifuge tube dish；Described centrifuge tube includes that body, connector and lid, described body are arranged in described through hole,
Described lid is connected with described body by described connector, and described connector is connected in described control dish；Described gland dish is pacified
Being contained on described control dish, described control dish is between described gland dish and described centrifuge tube dish, and described gland dish is used for controlling
Make the open angle of described lid.
Automatic mixing extraction apparatus the most according to claim 2, it is characterised in that be provided with many on the edge of described control dish
Individual breach, described breach is along the radially-inwardly depression of described control dish, and multiple described breach are circumferentially-spaced along described control dish
Arranging, and described breach is corresponding with the position of described through hole, described connector is connected in described breach.
Automatic mixing extraction apparatus the most according to claim 3, it is characterised in that described connector include the first contiguous block and
Second contiguous block, described first contiguous block is connected with described body, and described second contiguous block is connected with described lid, and described first
Contiguous block is rotationally connected with described second contiguous block, described second contiguous block along the radial rotating of described first contiguous block, first
The junction of contiguous block and described second contiguous block is positioned at described breach.
Automatic mixing extraction apparatus the most according to claim 4, it is characterised in that described connector also includes in compressive state
Back-moving spring, one end of described back-moving spring is arranged on described first contiguous block, and the other end of described back-moving spring is installed
On described second contiguous block, described back-moving spring makes described second contiguous block have the trend away from described first contiguous block.
Automatic mixing extraction apparatus the most according to claim 2, it is characterised in that described automatic feed liquor mechanism includes the machine of uncapping
Structure, liquid sucting mechanism, mechanism for filling liquid and pass lid mechanism, described cap-opening mechanism, described liquid sucting mechanism, described mechanism for filling liquid and described pass
Lid mechanism is separately mounted in described frame, described cap-opening mechanism, described liquid sucting mechanism, described mechanism for filling liquid and described pass lid machine
Structure is provided at circumferentially spaced along described centrifuge tube dish.
Automatic mixing extraction apparatus the most according to claim 6, it is characterised in that described cap-opening mechanism include the first cylinder and
Uncap portion, described in the portion of uncapping be installed on the outfan of described first cylinder, described in uncap the direction of motion in portion and described through hole
Direction of axis line is parallel, described in the portion of uncapping motion make described lid open；Described pass lid mechanism includes the second cylinder and closes cap,
Described pass cap is installed on the outfan of described second cylinder, the direction of motion of described pass cap and the axial line side of described through hole
To parallel, cap motion in described pass makes described cover closing.
Automatic mixing extraction apparatus the most according to claim 7, it is characterised in that described in the portion of uncapping include head rod and
First shifting block, one end of described head rod is installed on the outfan of described first cylinder, the axle center of described head rod
The axis parallel of line and described through hole, described first shifting block is installed on the other end of described head rod, described first group
Block motion makes described lid open；Described pass cap includes the second connecting rod and the second shifting block, one end of described second connecting rod
Outfan with described first cylinder, the axial line of described second connecting rod and the axis parallel of described through hole are installed, described
Second shifting block is installed on the other end of described second connecting rod, and described second shifting block motion makes described cover closing.
Automatic mixing extraction apparatus the most according to claim 1, it is characterised in that described rotating mechanism include the first motor and
First output shaft, described first motor is arranged in described frame, and described installing mechanism passes through described first output shaft with described
First motor connects, and described installing mechanism rotates along the axial line of described first output shaft.
Automatic mixing extraction apparatus the most according to claim 9, it is characterised in that described automatic mixing extraction apparatus also includes
Second motor and the second output shaft, described frame includes base and rotation dish, and described rotating mechanism is arranged on described rotation dish,
Described automatic feed liquor mechanism is arranged on described base, and described second motor is arranged on described base, and described rotation dish passes through
Described second output shaft is connected with described second motor, the axial line of described second output shaft and the axle center of described first output shaft
Line is vertical.
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| CN201610712565.1A CN106119086B (en) | 2016-08-24 | 2016-08-24 | A kind of automatic mixing extraction apparatus |
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| CN201610712565.1A CN106119086B (en) | 2016-08-24 | 2016-08-24 | A kind of automatic mixing extraction apparatus |
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| CN106119086B CN106119086B (en) | 2018-11-30 |
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| Publication number | Publication date |
|---|---|
| CN106119086B (en) | 2018-11-30 |
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