CN106117035B - A kind of method for lactic acid conversion to produce propionic acid - Google Patents
A kind of method for lactic acid conversion to produce propionic acid Download PDFInfo
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- CN106117035B CN106117035B CN201610505057.6A CN201610505057A CN106117035B CN 106117035 B CN106117035 B CN 106117035B CN 201610505057 A CN201610505057 A CN 201610505057A CN 106117035 B CN106117035 B CN 106117035B
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- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 title claims abstract description 117
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 title claims abstract description 110
- 238000006243 chemical reaction Methods 0.000 title claims abstract description 64
- 239000004310 lactic acid Substances 0.000 title claims abstract description 55
- 235000014655 lactic acid Nutrition 0.000 title claims abstract description 55
- 235000019260 propionic acid Nutrition 0.000 title claims abstract description 51
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 title claims abstract description 51
- 238000000034 method Methods 0.000 title claims abstract description 45
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 34
- 239000003054 catalyst Substances 0.000 claims abstract description 26
- 239000003638 chemical reducing agent Substances 0.000 claims abstract description 26
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 16
- 239000002028 Biomass Substances 0.000 claims abstract description 13
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 8
- 239000000843 powder Substances 0.000 claims description 29
- 239000002184 metal Substances 0.000 claims description 24
- 229910052751 metal Inorganic materials 0.000 claims description 24
- 230000035484 reaction time Effects 0.000 claims description 8
- 229910052742 iron Inorganic materials 0.000 claims description 5
- 238000001027 hydrothermal synthesis Methods 0.000 claims description 3
- 239000011261 inert gas Substances 0.000 claims description 3
- 229910052759 nickel Inorganic materials 0.000 claims description 3
- 229910052782 aluminium Inorganic materials 0.000 claims description 2
- 229910052802 copper Inorganic materials 0.000 claims description 2
- 229910052748 manganese Inorganic materials 0.000 claims description 2
- 229910052725 zinc Inorganic materials 0.000 claims description 2
- -1 catalyzer Substances 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 abstract description 10
- 229910052739 hydrogen Inorganic materials 0.000 abstract description 10
- 238000004519 manufacturing process Methods 0.000 abstract description 10
- 238000001914 filtration Methods 0.000 abstract description 8
- 239000002994 raw material Substances 0.000 abstract description 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract description 5
- 238000003912 environmental pollution Methods 0.000 abstract description 4
- 150000002431 hydrogen Chemical class 0.000 abstract description 3
- 230000015572 biosynthetic process Effects 0.000 abstract description 2
- 238000003786 synthesis reaction Methods 0.000 abstract description 2
- 239000000047 product Substances 0.000 description 29
- 239000000126 substance Substances 0.000 description 23
- 238000004128 high performance liquid chromatography Methods 0.000 description 20
- 238000002290 gas chromatography-mass spectrometry Methods 0.000 description 14
- 238000004445 quantitative analysis Methods 0.000 description 14
- 238000011049 filling Methods 0.000 description 9
- 230000008859 change Effects 0.000 description 7
- 238000004451 qualitative analysis Methods 0.000 description 6
- 239000004809 Teflon Substances 0.000 description 5
- 229920006362 Teflon® Polymers 0.000 description 5
- 230000010512 thermal transition Effects 0.000 description 5
- 239000011541 reaction mixture Substances 0.000 description 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 238000005265 energy consumption Methods 0.000 description 3
- 238000011065 in-situ storage Methods 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- 239000002253 acid Substances 0.000 description 2
- 230000004075 alteration Effects 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 239000003344 environmental pollutant Substances 0.000 description 2
- 239000002803 fossil fuel Substances 0.000 description 2
- 150000002500 ions Chemical class 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 229910044991 metal oxide Inorganic materials 0.000 description 2
- 150000004706 metal oxides Chemical class 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 230000007096 poisonous effect Effects 0.000 description 2
- 231100000719 pollutant Toxicity 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000003672 processing method Methods 0.000 description 2
- 238000006722 reduction reaction Methods 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 239000000020 Nitrocellulose Substances 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000010959 commercial synthesis reaction Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- BERDEBHAJNAUOM-UHFFFAOYSA-N copper(I) oxide Inorganic materials [Cu]O[Cu] BERDEBHAJNAUOM-UHFFFAOYSA-N 0.000 description 1
- KRFJLUBVMFXRPN-UHFFFAOYSA-N cuprous oxide Chemical compound [O-2].[Cu+].[Cu+] KRFJLUBVMFXRPN-UHFFFAOYSA-N 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229910000765 intermetallic Inorganic materials 0.000 description 1
- SZVJSHCCFOBDDC-UHFFFAOYSA-N iron(II,III) oxide Inorganic materials O=[Fe]O[Fe]O[Fe]=O SZVJSHCCFOBDDC-UHFFFAOYSA-N 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- GNMQOUGYKPVJRR-UHFFFAOYSA-N nickel(III) oxide Inorganic materials [O-2].[O-2].[O-2].[Ni+3].[Ni+3] GNMQOUGYKPVJRR-UHFFFAOYSA-N 0.000 description 1
- 229920001220 nitrocellulos Polymers 0.000 description 1
- 239000005416 organic matter Substances 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000007086 side reaction Methods 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000010189 synthetic method Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention discloses a kind of lactic acid to convert the method for producing propionic acid.The method comprises the following steps: lactic acid, catalyst, reducing agent and water are successively added into hydrothermal reactor；It is filled with nitrogen into above-mentioned hydrothermal reactor and seals；30~180min is reacted under the conditions of above-mentioned hydrothermal reactor is placed in 175~300 DEG C；After reaction, filtering is to get propionic acid solution.This method can be effectively synthesized propionic acid with high selectivity.The raw material that this method uses can derive from reproducible biomass energy, avoid the consumption of fossil energy, without the catalyst of synthesis complex and expensive, this method is easy to operate, high conversion rate, is not necessarily to pure hydrogen, is small using water as hydrogen source and reaction dissolvent environmental pollution, is conducive to industrialized production.
Description
Technical field
The present invention relates to field of energy and chemical technologys, and in particular to a kind of method that lactic acid conversion produces propionic acid, more specifically
It is a kind of method for preparing propionic acid using biomass derivatives lactic acid.
Background technique
Since 21 century, the shortage problem of environmental pollution and fossil fuel is more and more prominent, develops as a result, new renewable
Clean energy resource more and more paid close attention to by people with reducing dependence to fossil fuel.It is industrial wide both at home and abroad at present
The propionic acid synthetic method of general application be based primarily upon consumption fossil energy commercial synthesis method, the technique mainly have it is unsustainable, set
It is standby to require the disadvantages of high, severe reaction conditions and energy consumption are high.Non-renewable due to petroleum resources, reserves are inevitable increasingly withered
It exhausts, therefore has been imperative using reproducible raw material production propionic acid.And biomass energy have reproducibility, low pollution,
Widely distributed property and the abundant feature of total amount, there is very big application prospect.
Summary of the invention
The present invention provides a kind of method for preparing propionic acid based on biomass derivatives lactic acid (DL type), and this method is one
The completely new method of kind.This method does solvent and hydrogen source with water, and low energy consumption, and environmental pollution is small, is conducive to industrialized production, and convert
High-efficient, good product selectivity, catalyst is cheap and easy to get, easy to operate.Product propionic acid is as a kind of important chemical intermediate
And solvent, it is the important source material of esterifying agent, the solvent of nitrocellulose, plasticizer, chemical reagent and synthetic food raw material.
The purpose of the present invention is achieved through the following technical solutions:
A kind of method that lactic acid conversion produces propionic acid, the method are as follows: be added to the water lactic acid, catalyst, reducing agent, lazy
Property atmosphere under carry out hydro-thermal reaction, reaction temperature is 175~300 DEG C, 30~180min of reaction time, in reaction solution i.e.
Obtain propionic acid.
Preferably, the reaction system obtained after reaction is filtered to get propionic acid solution is arrived.
Preferably, the lactic acid, catalyst, reducing agent molar ratio be 1.5:(2~10): (5~25).
It is highly preferred that the molar ratio of the lactic acid, catalyst, reducing agent is 1.5:(4~6): (10~15).
Preferably, the reaction density of the lactic acid is 100~250mmol/L.
Preferably, the catalyst is selected from metal or metal oxide.It is highly preferred that the catalyst be selected from Co, Ni,
Cu、Fe、Fe2O3、CuO、Cu2O、Ni2O3Or Fe3O4One kind.It is further preferred that the catalyst is Co.
Preferably, the reducing agent is metal simple-substance powder.It is highly preferred that the metal simple-substance is Al, Fe, Mn or Zn.
It is further preferred that the metal simple-substance is Zn.
Preferably, the method that the lactic acid conversion produces propionic acid includes the following steps:
A, lactic acid, catalyst, reducing agent and water are sequentially added into hydrothermal reactor；
B, it is filled with nitrogen into above-mentioned hydrothermal reactor and seals；
C, 30~180min is reacted under the conditions of above-mentioned hydrothermal reactor being placed in 175~300 DEG C；
D, after reaction, filtering is to get propionic acid solution.
Preferably, the filling rate of water is 20~45% in the hydrothermal reactor.
The atmosphere of inert gases be in order to which air is sufficiently discharged, may be to reaction to avoid certain ingredients in air
It influences.
Preferably, the hydrothermal reactor, which is placed in baking oven, is reacted.
Preferably, in step D, the filtering is specially to be filtered using 0.45 μm of filter membrane.
In the method for the invention, water reacts 30~180min in 175~300 DEG C under the conditions of in hydrothermal reactor
High-temperature high pressure water；The dielectric constant of high-temperature high pressure water has reduction than normal-temperature water, and intermolecular hydrogen bond weakens, and isothermal compressibility mentions
Height, ion constant (Kw) almost increase 1000 times than normal-temperature water.
The reaction process are as follows: the reducing agent is reacted with water generates in-situ hydrogen, and then the in-situ hydrogen and the cream
Two step reduction reactions occur under the catalyst action for acid, so the present invention can be complete in the condition without being additionally passed through pure hydrogen
At the synthesis of propionic acid.
In addition, specific example is as follows there is also some possible side reaction processes in the above process:
Preferably, the lactic acid is biomass derivatives lactic acid.Utilize one of the reaction of biomass derivatives lactic acid producing
Example can be found in Y.Fang et al., Industrial&Engineering Chemistry Research, and 2012,51
(12):4759-4763。
Compared with prior art, the present invention have it is following the utility model has the advantages that
(1) high-temperature high pressure water is generated in reaction process of the present invention make reaction dissolvent, compared with light water, high-temperature high pressure water
Dielectric constant reduces, and intermolecular hydrogen bond weakens, and isothermal compressibility improves, and ion constant (Kw) is almost increased than normal-temperature water
1000 times, using these characteristics of high-temperature high pressure water, it can be achieved that making reducing agent with metal and its compound cheap and easy to get and urging
Lactic acid is transformed into this high added value organic matter of propionic acid under hydrothermal conditions by agent, realizes that efficient low-consume converts organic money
Source；
(2) present invention utilizes water to production hydrogen in situ, avoids the storage transport of hydrogen, significantly reduces energy consumption of reaction,
And it is more environmentally protective, environmental pollution is small；
(3) reducing agent and catalyst can be recovered or make other production purposes in the method for the present invention, thus to a certain extent
It reduces and is discharged into the pollutant component of environment, reduces production cost.
(4) research for producing propionic acid is converted about lactic acid at present only have biological fermentation process, and the present invention is spread out using biomass
Biological lactic acid prepares propionic acid as raw material, proposes pioneeringly and produces propionic acid using chemical method conversion lactic acid, fast and effeciently realizes
Propionic acid production based on renewable bioenergy；
(5) present invention using can by biomass energy obtain lactic acid as raw material production propionic acid, it is green non-poisonous, be not easy to produce
Raw poisonous and harmful substance；
(6) propionic acid yield of the present invention is up to 58.79%, and selectivity is good, and byproduct of reaction is few.
Certainly, it implements any of the products of the present invention and does not necessarily require achieving all the advantages described above at the same time.
Detailed description of the invention
Fig. 1 is the HPLC spectrogram of the product of the embodiment of the present invention 1；Wherein, RID and VWD represents the two of the liquid phase of the sample
Kind signal.
Specific embodiment
The present invention provides a kind of method that lactic acid conversion produces propionic acid, the method are as follows: add lactic acid, catalyst, reducing agent
Entering in water, hydro-thermal reaction is carried out under atmosphere of inert gases, reaction temperature is 175~300 DEG C, 30~180min of reaction time,
Propionic acid is obtained in reaction solution.
Herein, the range indicated by " numerical value to another numerical value ", is that one kind avoids enumerating in the description
The summary representation of all numerical value in the range.Therefore, the record of a certain special value range, covers the numberical range
Interior any number and the relatively fractional value range defined by any number in the numberical range, as bright in the description
Text writes out any number as should be compared with fractional value range.
Present invention will be further explained below with reference to specific examples.It should be understood that these embodiments are merely to illustrate this hair
It is bright, rather than limit the scope of protection of the present invention.What those skilled in the art made according to the present invention in practical applications changes
Into and adjustment, still fall within protection scope of the present invention.
Embodiment 1
The present embodiment is related to a kind of water of metal simple-substance (Zn powder) as reducing agent, metal simple-substance (Co powder) as catalyst
The method that thermal transition lactic acid prepares propionic acid, reaction equation are as follows:
The preparation method of the present embodiment includes the following steps:
Successively lactic acid (1.5mmol, reaction density 200mmol/L), Zn powder (10mmol) and Co powder (4mmol) are packed into
In the hydrothermal reactor of Teflon liner, water is added to make reactor filling rate 25%, nitrogen is filled with into reactor and excludes air
Interference after seal, reactor, which is put into baking oven, makes 250 DEG C of its reaction temperature, and reaction time 120min takes out after reaction
Mixture filtering can obtain propionic acid solution.
Will reaction after product propionic acid solution with HPLC analyze (see attached drawing 1), it is that Fig. 1 is shown the result shows that: propionic acid is main
Product, yield is up to 58.79%.
Embodiment 2
The present embodiment is related to a kind of water of metal simple-substance (Zn powder) as reducing agent, metal simple-substance (Co powder) as catalyst
The method that thermal transition lactic acid prepares propionic acid, described method includes following steps:
Successively lactic acid (1.5mmol, reaction density 200mmol/L), Zn powder (10mmol) and Co powder (4mmol) are packed into
In the hydrothermal reactor of Teflon liner, water is added to make reactor filling rate 25%, nitrogen is filled with into reactor and excludes air
Interference after seal, reactor, which is put into baking oven, makes 225 DEG C of its reaction temperature, and reaction time 180min takes out after reaction
Mixture filtering can obtain propionic acid solution.
Product propionic acid solution after reaction is analyzed with HPLC, the results showed that propionic acid is primary product, and yield is up to 42.75%.
Embodiment 3
The present embodiment is related to a kind of water of metal simple-substance (Zn powder) as reducing agent, metal simple-substance (Co powder) as catalyst
The method that thermal transition lactic acid prepares propionic acid, described method includes following steps:
Successively lactic acid (1.5mmol, reaction density 200mmol/L), Zn powder (10mmol) and Co powder (4mmol) are packed into
In the hydrothermal reactor of Teflon liner, water is added to make reactor filling rate 25%, nitrogen is filled with into reactor and excludes air
Interference after seal, reactor, which is put into baking oven, makes 250 DEG C, reaction time 90min of its reaction temperature, takes out after reaction mixed
Propionic acid solution can be obtained by closing object filtering.
Product propionic acid solution after reaction is analyzed with HPLC, the results showed that propionic acid is primary product, and yield is up to 48.05%.
Embodiment 4
The present embodiment is related to a kind of water of metal simple-substance (Zn powder) as reducing agent, metal simple-substance (Co powder) as catalyst
The method that thermal transition lactic acid prepares propionic acid, described method includes following steps:
Successively lactic acid (1.5mmol, reaction density 125mmol/L), Zn powder (10mmol) and Co powder (4mmol) are packed into
In the hydrothermal reactor of Teflon liner, water is added to make reactor filling rate 40%, nitrogen is filled with into reactor and excludes air
Interference after seal, reactor, which is put into baking oven, makes 250 DEG C of its reaction temperature, and reaction time 120min takes out after reaction
Mixture filtering can obtain propionic acid solution.
Product propionic acid solution after reaction is analyzed with HPLC, the results showed that propionic acid is primary product, and yield is up to 54.03%.
Embodiment 5
The present embodiment is related to a kind of water of metal simple-substance (Zn powder) as reducing agent, metal simple-substance (Co powder) as catalyst
The method that thermal transition lactic acid prepares propionic acid, described method includes following steps:
Successively lactic acid (1.5mmol, reaction density 250mmol/L), Zn powder (10mmol) and Co powder (4mmol) are packed into
In the hydrothermal reactor of Teflon liner, water is added to make reactor filling rate 20%, nitrogen is filled with into reactor and excludes air
Interference after seal, reactor, which is put into baking oven, makes 250 DEG C of its reaction temperature, and reaction time 120min takes out after reaction
Mixture filtering can obtain propionic acid solution.
Product propionic acid solution after reaction is analyzed with HPLC, the results showed that propionic acid is primary product, and yield is up to 53.61%.
Embodiment 6
The present embodiment is the change case of embodiment 1, and technical solution is same as Example 1, be the difference is that only, reducing agent
For metal simple-substance Al (10mmol)；The filling rate of water is 25% in hydrothermal reactor；Reaction condition is 250 DEG C, 120min.
Product carries out qualitative and HPLC quantitative analysis with GC/MS after reacting, and GC/MS qualitative analysis shows based on propionic acid
Product is wanted, HPLC quantitative analysis shows yield up to 52.75%.
Embodiment 7
The present embodiment is the change case of embodiment 1, and technical solution is same as Example 1, be the difference is that only, lactic acid,
Catalyst (Co powder), reducing agent (metal simple-substance Zn powder) molar ratio be 1.5:2:10；The filling rate of water is in hydrothermal reactor
25%；Reaction condition is 250 DEG C, 120min.Product carries out qualitative and HPLC quantitative analysis with GC/MS after reacting, and GC/MS is fixed
Property analysis shows, propionic acid is primary product, and HPLC quantitative analysis shows yield up to 36.38%.
Embodiment 8
The present embodiment is the change case of embodiment 7, and technical solution is same as Example 1, be the difference is that only, lactic acid,
Catalyst (Co powder), reducing agent (metal simple-substance Zn powder) molar ratio be 1.5:10:25.
Product carries out qualitative and HPLC quantitative analysis with GC/MS after reacting, and GC/MS qualitative analysis shows based on propionic acid
Product is wanted, HPLC quantitative analysis shows yield up to 56.20%.
Embodiment 9
The present embodiment is the change case of embodiment 1, and technical solution is same as Example 1, be the difference is that only, catalyst
For metal oxide CuO (4mmol)；The filling rate of water is 25% in hydrothermal reactor；Reaction condition is 250 DEG C, 120min.
Product carries out qualitative and HPLC quantitative analysis with GC/MS after reacting, and GC/MS qualitative analysis shows based on propionic acid
Product is wanted, HPLC quantitative analysis shows that yield is 2.79%.
Embodiment 10
The present embodiment is the change case of embodiment 1, and technical solution is substantially the same manner as Example 1, the difference is that, cream
Acid, catalyst (Co powder), reducing agent (metal simple-substance Zn powder) molar ratio be 1.5:2:5.
Product carries out qualitative and HPLC quantitative analysis with GC/MS after reacting, and GC/MS qualitative analysis shows based on propionic acid
Product is wanted, HPLC quantitative analysis shows that yield is 6.21%.
Embodiment 11
The present embodiment is the change case of embodiment 1, and technical solution is substantially the same manner as Example 1, the difference is that, hydro-thermal
Reactor is set to 175 DEG C of reaction 60min.
Product carries out qualitative and HPLC quantitative analysis with GC/MS after reacting, and GC/MS qualitative analysis shows based on propionic acid
Want product, HPLC quantitative analysis shows yield highest only 1.65%.
Embodiment 12
The present embodiment is the change case of embodiment 1, and technical solution is same as Example 1, the difference is that, reducing agent is
Metal simple-substance Fe (10mmol).
Product carries out qualitative and HPLC quantitative analysis with GC/MS after reacting, and GC/MS qualitative analysis shows based on propionic acid
Product is wanted, HPLC quantitative analysis shows that yield is 1.15%.
Embodiment 13
The present embodiment uses the lactic acid of biomass source, and general scheme is as follows:
Wherein, first step reaction condition are as follows: 0.01M NaOH, 0.01M Ni2+, 0.035g biomass, 2mL H2O,300
DEG C, 1min, the biomass is glucose, cellulose or starch.Then contain lactic acid using what the first step obtained after reaction
Solution carry out the reaction that the conversion of second step lactic acid produces propionic acid, reaction condition are as follows: 0.76mmol Co, 1.9mmol Zn, 300 DEG C,
60min.The yield results of final reacting product are as shown in table 1 below.
Table 1
The present embodiment is able to demonstrate that the lactic acid of biomass source effectively can be converted to propionic acid by method of the invention.
Wherein, remaining metal simple-substance and remaining metallic compound can be recovered or make after reaction under hydrothermal condition
Other production purposes, to reduce the pollutant component for being discharged into environment to a certain extent.
Under the teaching of the present invention and the above embodiments, those skilled in the art are easy to it is envisioned that cited by the present invention
Or each raw material enumerated or its equivalent alterations, each processing method or its equivalent alterations can realize the present invention and each original
The parameter bound value of material and processing method, interval value can realize the present invention, embodiment numerous to list herein.
Specific embodiments of the present invention are described above.It is to be appreciated that the invention is not limited to above-mentioned
Particular implementation, those skilled in the art can make various deformations or amendments within the scope of the claims, this not shadow
Ring substantive content of the invention.
Claims (8)
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| CN110229058B (en) * | 2019-07-18 | 2021-08-03 | 重庆理工大学 | A kind of method for preparing propionic acid by catalytic conversion of lactic acid |
| CN112604610B (en) * | 2020-12-23 | 2022-04-22 | 河南金丹乳酸科技股份有限公司 | Method for preparing propionic acid by lactic acid catalysis |
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