CN106110234A - A kind of can effective endo-medicine treating hepatitis B and preparation method thereof - Google Patents

A kind of can effective endo-medicine treating hepatitis B and preparation method thereof Download PDF

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CN106110234A
CN106110234A CN201610812924.0A CN201610812924A CN106110234A CN 106110234 A CN106110234 A CN 106110234A CN 201610812924 A CN201610812924 A CN 201610812924A CN 106110234 A CN106110234 A CN 106110234A
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medicine
radix
herba
rhizoma
hepatitis
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罗娟
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Chengdu Feilong Water Treatment Technology Institute
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Chengdu Feilong Water Treatment Technology Institute
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/90Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger

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Abstract

The invention belongs to technical field of Chinese medicine, purpose is a kind of endo-medicine that can effectively treat hepatitis B according to the traditional Chinese medical science, hepatitis B being recognized mechanism and providing, and each component of described medicine and mass parts ratio thereof are as follows: Fructus Phyllanthi 15~32g, Cacumen Securinegae Suffruticosae 25~45g, the Rhizoma Atractylodis Macrocephalae 8~16g, Radix Glycyrrhizae 2.5~16g, Radix Curcumae 8~16g, Radix Sophorae Flavescentis 3~12g, Herba Lysimachiae 15~26g, Herba Sophorae alopecuroidis 2.5~5g, Radix Sophorae Tonkinensis 3~9g, Rhizoma Polygoni Cuspidati 15~46g, Herba Artemisiae Scopariae 6~16g, Rhizoma Smilacis Glabrae 15~50g;The medicine that the present invention provides is a good Chinese prescription.

Description

A kind of can effective endo-medicine treating hepatitis B and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicine, be specifically related to a kind of endo-medicine that can effectively treat hepatitis B, special It it not the field of endo-medicine for chronic hepatitis B patient and preparation method thereof.
Background technology
Doctor thinks: chronic hepatitis B (abbreviation hepatitis B) refers to hepatitis B virus test positive, the course of disease exceed half a year or Date of the onset is indefinite and clinic has chronic hepatitis shower.Clinical manifestation is weak, sitophobia, feel sick, abdominal distention, hepatalgia etc. Symptom.Hepatomegaly, quality is medium hardness, has light tenderness.State of an illness severe one can be with chronic hepatopathy face, spider angioma, liver palm, spleen Greatly, liver function can exception or persistent anomaly.Be divided into slightly according to clinical manifestation, moderate and severe.And chronic viral hepatitis B carries and refers to Hepatitis B virus test positive, without chronic hepatitis symptom, follows up a case by regular visits to more than three times Serum ALT continuously and AST is all as good as in 1 year Often, and liver histological check normal person.
So, just how to find a kind of medicine that can effectively treat above-mentioned chronic hepatitis B, be that we are badly in need of wanting at present The problem solved.
Summary of the invention
Along with the development of China's Chinese medicine, on treatment chronic hepatitis B, during people gradually appreciate Cure the advantage treating above-mentioned chronic hepatitis B, and the advantage such as toxic and side effects is little over the course for the treatment of, expense is low, for existing west Cure the present situation treating above-mentioned chronic hepatitis B, it is an object of the invention to be that providing a kind of can effectively treat the interior of hepatitis B Take medicine thing, to solve the most restorative problem of chronic hepatitis B patient.This medicine is with common Chinese medicine as raw material, tool There are instant effect, the feature such as evident in efficacy, and can effectively treat above-mentioned hepatitis B one card.
For reaching the purpose of foregoing invention, the technical solution adopted in the present invention is: provide one can effectively treat B-mode Endo-medicine of hepatitis and preparation method thereof, it is characterised in that each component of described medicine and mass parts ratio thereof are as follows:
Fructus Phyllanthi 15~32g, Cacumen Securinegae Suffruticosae 25~45g, the Rhizoma Atractylodis Macrocephalae 8~16g, Radix Glycyrrhizae 2.5~16g, Radix Curcumae 8~16g, Radix Sophorae Flavescentis 3~ 12g, Herba Lysimachiae 15~26g, Herba Sophorae alopecuroidis 2.5~5g, Radix Sophorae Tonkinensis 3~9g, Rhizoma Polygoni Cuspidati 15~46g, Herba Artemisiae Scopariae 6~16g, Rhizoma Smilacis Glabrae 15~ 50g。
A kind of can effective endo-medicine treating hepatitis B and preparation method thereof, it is characterised in that described medicine each Individual component and mass parts ratio thereof are as follows:
Fructus Phyllanthi 18~28g, Cacumen Securinegae Suffruticosae 30~40g, the Rhizoma Atractylodis Macrocephalae 10~14g, Radix Glycyrrhizae 8~14g, Radix Curcumae 10~14g, Radix Sophorae Flavescentis 8~ 11g, Herba Lysimachiae 18~23g, Herba Sophorae alopecuroidis 3~4.5g, Radix Sophorae Tonkinensis 6~8g, Rhizoma Polygoni Cuspidati 20~40g, Herba Artemisiae Scopariae 8~14g, Rhizoma Smilacis Glabrae 20~ 42g。
A kind of can effective endo-medicine treating hepatitis B and preparation method thereof, it is characterised in that described " the most square Case " each component of medicine and mass parts ratio as follows:
Fructus Phyllanthi 25g, Cacumen Securinegae Suffruticosae 35g, Rhizoma Atractylodis Macrocephalae 13g, Radix Glycyrrhizae 12g, Radix Curcumae 13g, Radix Sophorae Flavescentis 10g, Herba Lysimachiae 20g, Herba Sophorae alopecuroidis 4g, mountain Radix Sophorae Tonkinensis 7g, Rhizoma Polygoni Cuspidati 35g, Herba Artemisiae Scopariae 13g, Rhizoma Smilacis Glabrae 36g.
A kind of can effective endo-medicine treating hepatitis B and preparation method thereof, it is characterised in that described method includes Following steps are prepared from:
A, above-mentioned raw materials Chinese medicine is picked decontamination and dust after, be respectively crushed into coarse according to mass parts ratio and decoct a drug wrapped;
B, the raw material Chinese medicine wrapped is put in cold boiled water immersion half an hour, the most again by soaked medicine and soak medicine Clear liquor put into marmite in the lump, injected the cold boiled water of medicine 35mm and carry out decocting 45 minutes for the first time, after leaching medicinal liquid, then The secondary tepor boiled water injecting medicine 33mm carries out second time and decocts 35 minutes, and secondary mixing is condensed into the herb liquid 600 milliliters of 50% Standby.
A kind of can effective endo-medicine treating hepatitis B and preparation method thereof, it is characterised in that described instructions of taking For: being taken with one day by the herb liquid prepared, the morning, noon and afternoon service once, dosage 200 milliliter/time, taking medicine before meal, take medicine 180 Yu Tian, symptom gradually alleviates or fully recovers.
Each raw material Chinese medicine in prescription of the present invention all has detailed note in Chinese Pharmacopoeia, China's dictionary and China's book on Chinese herbal medicine Carry.The present invention selects most common of which Chinese medicine to be raw material, gives full play to the pharmacological effect of each component:
Fructus Phyllanthi, nature and flavor: bitter in the mouth, sweet, sour, cool in nature, there is effect of relieving sore-throat by clearing away heat, moistening the lung and resolving phlegm, promoting the production of body fluid to quench thirst, be used for treating The diseases such as cold, fever, cough, pharyngalgia, diphtheria, thirsty, the hypertension of dysphoria with smothery sensation;
Cacumen Securinegae Suffruticosae, nature and flavor: micro-hardship, sweet, cool, there is effect of clearing away heat and promoting diuresis, improving eyesight, removing food stagnancy, be used for treating oedema due to nephritis, urinary system System infection, calculus, enteritis, dysentery, young waiter in a wineshop or an inn's infantile malnutrition, eye keratitis, icterohepatitis, external is controlled Trimeresurus stejnegeri and the disease such as is bitten;
The Rhizoma Atractylodis Macrocephalae, nature and flavor: bitter in the mouth, sweet, warm in nature, there is invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect, be used for treating temper The few abdominal distention of weakness, spiritlessness and weakness, lack of appetite, big loose stool are thin, fluid-retention stagnating in the interior, dysuria, edema, dizziness due to fluid-retention, temperature numbness are ached, gas The empty disease such as spontaneous perspiration, frequent fetal movement;
Radix Glycyrrhizae, nature and flavor: sweet, flat, have and middle emergency, lung moistening, removing toxic substances, effect of coordinating the actions of various ingredients in a prescription, be used for treating weakness of the spleen and stomach, food Less, stomachache loose stool, overstrain heating, consumptive lung disease cough, cardiopalmus, infantile convulsion, give birth to controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores, solution Poison of drug and alimentary toxicosis;
Radix Curcumae, nature and flavor: acrid in the mouth, hardship, cold in nature, there is promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, effect of depressed liver-energy dispersing and function of gallbladder promoting, use In the treatment chest and abdomen side of body all pains of rib, dysmenorrhes, amenorrhea, lump in the abdomen caking, calentura coma, demented, infantile convulsion, spit blood, standby, the stranguria with blood of being defeated in battle, The disease such as sand Stranguria, jaundice;
Radix Sophorae Flavescentis, nature and flavor: bitter in the mouth, cold in nature, there is effect of heat clearing away, dampness, parasite killing, be used for treating toxic-heat and blood stasis, discharging fresh blood stool, Huang Subcutaneous ulcer, leucorrhea with red and white discharge, infantile pneumonia, infantile malnutrition, acute tonsillitis, anal fistula, proctoptosis, skin pruritus, erosion of vulva pruritus due to damp pathogen, scrofula, scald;
Herba Lysimachiae, nature and flavor: hardship sweet, micro-, cool in nature, there is effect of relieving stranguria by diuresis, heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, be used for treating liver The diseases such as gallbladder and urinary system calculus, pyretic stranguria, oedema due to nephritis, jaundice due to damp-heat, sore carbuncle, venom, traumatic injury;
Herba Sophorae alopecuroidis, nature and flavor: bitter, cold, poisonous, there is heat clearing and damp drying;Pain relieving;Effect of parasite killing, is used for treating dysentery, stomachache, white Band is too much, eczema, furuncle stubborn dermatitis;
Radix Sophorae Tonkinensis, nature and flavor: bitter, cold, poisonous, there is heat-clearing and toxic substances removing, effect of detumescence sore-throat relieving, be used for treating fire-toxin pent up, throat Swell and ache, gingivitis;
Rhizoma Polygoni Cuspidati, nature and flavor: bitter, sour, cold nature, there is effect of promoting blood circulation to remove blood stasis, dispelling wind and removing obstruction in the collateral, clearing away heat-damp and promoting diuresis, removing toxic substances, be used for treating The accumulation of women's amenorrhea, dysmenorrhea, lochiostasis, abdominal mass, injury from falling down, rheumatic arthralgia, jaundice due to damp-heat, stranguria with turbid discharge leukorrhagia, skin infection swell The diseases such as poison, venom, burn due to hot liquid or fire;
Herba Artemisiae Scopariae, nature and flavor: bitter, pungent, be slightly cold, there is clearing away damp-heat, effect of jaundice eliminating subcutaneous ulcer, be used for treating jaundice oliguria, eczema pruritus, biography Metachromia icterohepatitis;
Rhizoma Smilacis Glabrae, nature and flavor: sweet, light, flat, there is dehumidifying, removing toxic substances, effect of easing joint movement, be used for treating damp and hot stranguria with turbid discharge, leukorrhagia, Carbuncle, scrofula, scabies, syphilis and the limbs contracture caused by mercurialism, bones and muscles pain.
Medicine of the present invention is differential diagnosis of diseases based on Chinese traditional treatment hepatitis B and the dialectical principle combined, from pharmacological action and Mechanism of action is thought: demonstrate,prove with regard to hepatitis B one, and each raw material herbal medicine efficacy in medicine provided by the present invention is played, altogether to above-mentioned disease Disease has good therapeutic effect.
Detailed description of the invention
The present invention is aiming at the treatment of above-mentioned hepatitis B and a kind of Chinese medicine formula of proposing, uses this formula to prepare Medicine effect is good, instant effect, is the Chinese prescription of a treating both the principal and secondary aspects of a disease, is particularly suitable for Clinical practice.Below in conjunction with the present invention's Detailed description of the invention is described in further detail:
Embodiment 1:
A kind of endo-medicine that can effectively treat hepatitis B, it is characterised in that each component of described medicine and mass parts thereof Ratio is as follows:
Fructus Phyllanthi 28g, Cacumen Securinegae Suffruticosae 40g, Rhizoma Atractylodis Macrocephalae 14g, Radix Glycyrrhizae 14g, Radix Curcumae 14g, Radix Sophorae Flavescentis 11g, Herba Lysimachiae 23g, Herba Sophorae alopecuroidis 4.5g, Radix Sophorae Tonkinensis 8g, Rhizoma Polygoni Cuspidati 40g, Herba Artemisiae Scopariae 14g, Rhizoma Smilacis Glabrae 20~42g.
Embodiment 2:
A kind of endo-medicine that can effectively treat hepatitis B, it is characterised in that each component of described medicine and mass parts thereof Ratio is as follows:
Fructus Phyllanthi 28g, Cacumen Securinegae Suffruticosae 40g, Rhizoma Atractylodis Macrocephalae 14g, Radix Glycyrrhizae 14g, Radix Curcumae 14g, Radix Sophorae Flavescentis 11g, Herba Lysimachiae 23g, Herba Sophorae alopecuroidis 4.5g, Radix Sophorae Tonkinensis 8g, Rhizoma Polygoni Cuspidati 40g, Herba Artemisiae Scopariae 14g, Rhizoma Smilacis Glabrae 42g.
Embodiment 3:
A kind of endo-medicine that can effectively treat hepatitis B, it is characterised in that each component of described medicine and mass parts thereof Ratio is as follows:
Fructus Phyllanthi 32g, Cacumen Securinegae Suffruticosae 45g, Rhizoma Atractylodis Macrocephalae 16g, Radix Glycyrrhizae 16g, Radix Curcumae 16g, Radix Sophorae Flavescentis 12g, Herba Lysimachiae 26g, Herba Sophorae alopecuroidis 5g, mountain Radix Sophorae Tonkinensis 9g, Rhizoma Polygoni Cuspidati 46g, Herba Artemisiae Scopariae 16g, Rhizoma Smilacis Glabrae 50g.
Model case:
Through clinical conditions hepatitis B patient totally 190 example, the age is 125 examples of more than 37 years old, only 65 examples be 37 years old with Under.175 examples of recovery from illness in 190 example patients, 15 effective examples, total effective rate reaches 100%.Symptom gradually alleviates or fully recovers.

Claims (3)

1. the endo-medicine that can effectively treat hepatitis B, it is characterised in that each component of described medicine and quality thereof Part ratio is as follows:
Fructus Phyllanthi 15~32g, Cacumen Securinegae Suffruticosae 25~45g, the Rhizoma Atractylodis Macrocephalae 8~16g, Radix Glycyrrhizae 2.5~16g, Radix Curcumae 8~16g, Radix Sophorae Flavescentis 3~ 12g, Herba Lysimachiae 15~26g, Herba Sophorae alopecuroidis 2.5~5g, Radix Sophorae Tonkinensis 3~9g, Rhizoma Polygoni Cuspidati 15~46g, Herba Artemisiae Scopariae 6~16g, Rhizoma Smilacis Glabrae 15~ 50g。
The endo-medicine that can effectively treat hepatitis B the most according to claim 1, it is characterised in that described medicine each Individual component and mass parts ratio thereof are as follows:
Fructus Phyllanthi 18~28g, Cacumen Securinegae Suffruticosae 30~40g, the Rhizoma Atractylodis Macrocephalae 10~14g, Radix Glycyrrhizae 8~14g, Radix Curcumae 10~14g, Radix Sophorae Flavescentis 8~ 11g, Herba Lysimachiae 18~23g, Herba Sophorae alopecuroidis 3~4.5g, Radix Sophorae Tonkinensis 6~8g, Rhizoma Polygoni Cuspidati 20~40g, Herba Artemisiae Scopariae 8~14g, Rhizoma Smilacis Glabrae 20~ 42g。
3. according to the endo-medicine that can effectively treat hepatitis B described in claim 1 to 2, it is characterised in that described medicine Each component and mass parts ratio as follows:
Fructus Phyllanthi 25g, Cacumen Securinegae Suffruticosae 35g, Rhizoma Atractylodis Macrocephalae 13g, Radix Glycyrrhizae 12g, Radix Curcumae 13g, Radix Sophorae Flavescentis 10g, Herba Lysimachiae 20g, Herba Sophorae alopecuroidis 4g, mountain Radix Sophorae Tonkinensis 7g, Rhizoma Polygoni Cuspidati 35g, Herba Artemisiae Scopariae 13g, Rhizoma Smilacis Glabrae 36g.
CN201610812924.0A 2016-09-09 2016-09-09 A kind of can effective endo-medicine treating hepatitis B and preparation method thereof Withdrawn CN106110234A (en)

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