CN106109817A

CN106109817A - The Chinese medicine composition for the treatment of hyperlipidemia

Info

Publication number: CN106109817A
Application number: CN201610826481.0A
Authority: CN
Inventors: 吕迎丽; 李英涛; 王庆涛
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-09-14
Filing date: 2016-09-14
Publication date: 2016-11-16

Abstract

The present invention relates to a kind of pharmaceutical formulation field, a kind of Chinese medicine composition treating hyperlipidemia, it is characterized in that being made up of the crude drug of following weight portion: Semen Cassiae 10～15 parts, Radix Paeoniae Rubra 15～20 parts, Herba Taxilli 15～20 parts, Rhizoma Chuanxiong 10～12 parts, Herba Lycopodii 2～4 parts, Folium Pyrrosiae 6～10 parts, Radix Angelicae Sinensis 10～15 parts, Fructus Leonuri 10～15 parts, the Radix Astragali 6～12 parts, Rhizoma Cyperi 6～8 parts, three pairs are saved 10～15 parts, Fructus Forsythiae 30～35 parts, Rhizoma Atractylodis 10～15 parts, Herba Canscorae 6～8 parts, Fructus Piperis Longi 10～15 parts, Herba Eupatorii 4～6 parts, gold lion rattan 10～15 parts, Radix Peucedani 10～15 parts, Herb Gynostemmae Pentaphylli 6～8 parts, Radix Aconiti Lateralis Preparata 6～8 parts, by medicinal for above-mentioned raw materials water soaking, remove slag after decocting to obtain filtrate.

Description

The Chinese medicine composition for the treatment of hyperlipidemia

Technical field

The present invention relates to a kind of Chinese patent medicine preparation, a kind of Chinese medicine composition treating hyperlipidemia.

Background technology

It is known that in recent years, at home and abroad, the M & M of cardiovascular and cerebrovascular disease is all in rising state year by year Gesture, it has also become a class disease of serious harm human health.Cardiovascular and cerebrovascular disease is mostly derived from atherosclerosis, and 80% with On atherosclerosis caused by hyperlipidemia.

At present blood fat reducing series products the most commercially is a lot, the Western medicine product based on Statins account for the 80% of the market share with On, although this kind of medicine quick result, Most patients just can bring about tangible results in short several days, but, high blood Fat is a kind of chronic disease, and its treatment needs long-term, takes medicine the most all the life, somewhat expensive, it is most important that many patients are taking During easily cause liver function damage, glutamate pyruvate transaminase raises, and blood urea nitrogen raises, and human body is produced untoward reaction, and dependency is also Stronger, it is unfavorable for long-term taking.

Summary of the invention

The purpose of the present invention is contemplated to overcome above-mentioned existing technical deficiency, it is provided that a kind of Chinese drug-treated group treating hyperlipidemia Compound, determined curative effect, safe ready, side effect is little, price is low.

The present invention solves above-mentioned technical problem and the technical scheme is that a kind of Chinese medicine composition treating hyperlipidemia, its It is characterised by being made up of the crude drug of following weight portion: Semen Cassiae 10～15 parts, Radix Paeoniae Rubra 15～20 parts, Herba Taxilli 15～20 parts, Rhizoma Chuanxiong 10～12 parts, Herba Lycopodii 2～4 parts, Folium Pyrrosiae 6～10 parts, Radix Angelicae Sinensis 10～15 parts, Fructus Leonuri 10～15 parts, the Radix Astragali 6～12 Part, Rhizoma Cyperi 6～8 parts, three to 10～15 parts of joint, Fructus Forsythiae 30～35 parts, Rhizoma Atractylodis 10～15 parts, Herba Canscorae 6～8 parts, Fructus Piperis Longi 10～ 15 parts, Herba Eupatorii 4～6 parts, gold lion rattan 10～15 parts, Radix Peucedani 10～15 parts, Herb Gynostemmae Pentaphylli 6～8 parts, Radix Aconiti Lateralis Preparata 6～8 parts, by above-mentioned former Expect medicinal water soaking, filtrate of removing slag after decocting to obtain.

The invention has the beneficial effects as follows: determined curative effect, safe ready, side effect is little, price is low.

Detailed description of the invention

Below in conjunction with embodiment, the invention will be further described:

Embodiment 1:

Its component (weight portion) is, Semen Cassiae 12 parts, Radix Paeoniae Rubra 20 parts, Herba Taxilli 20 parts, Rhizoma Chuanxiong 10 parts, Herba Lycopodii 2 parts, Folium Pyrrosiae 6 Part, Radix Angelicae Sinensis 12 parts, Fructus Leonuri 14 parts, the Radix Astragali 10 parts, Rhizoma Cyperi 6 parts, three to joint 12 parts, Fructus Forsythiae 32 parts, Rhizoma Atractylodis 12 parts, Herba Canscorae 6 Part, Fructus Piperis Longi 12 parts, Herba Eupatorii 4 parts, gold 12 parts of lion rattan, Radix Peucedani 10 parts, Herb Gynostemmae Pentaphylli 8 parts, Radix Aconiti Lateralis Preparata 8 parts, take above-mentioned 20 kinds of crude drug total Weight is 200 grams, and Chinese herbal medicine at room temperature adds water to 800～1000ml, soaks 3～5 minutes, boils slow fire the most with high heat Decocting about 90～100 minutes, remove slag to obtain filtrate 200ml, and medicinal residues add water 250～300ml, decocts 30～40 minutes, removes slag Obtain filtrate 100ml, there are about 300ml medicine juice, i.e. prepare Chinese medicine decoction of the present invention.Load in sterile glass vials, seal bottle cap Standby, every day 1 dose point is administered orally for 2 times, and the most oral about 150ml takes rear Clinical symptom and sign and disappears, then consolidates curative effect Take 1 week.

In medicine of the present invention, Semen Cassiae loosening bowel to relieve constipation, blood fat reducing improving eyesight, treatment constipation and hyperlipidemia, hypertension；Radix Paeoniae Rubra has clearly Hot removing heat from blood, effect of blood circulation promoting and blood stasis dispelling；Herba Taxilli has wind-damp dispelling, liver and kidney tonifying, bone and muscle strengthening, antiabortive effect；Rhizoma Chuanxiong activating QI to alleviate the depression, method Wind-dryness is wet, promoting blood circulation and stopping pain；Herba Lycopodii expelling wind and cold, dehumidifying detumescence, relaxing muscles and tendons and activating QI and blood in the collateral；Folium Pyrrosiae has relieving stranguria by diuresis, lung heat clearing to expel the heat-evil etc. to make With；Chinese angelica blood supplementing, invigorates blood circulation, and menstruction regulating and pain relieving moisturizes laxation；Fructus Leonuri has promoting blood flow to regulate menstruation, effect of liver heat removing and eyesight improving；The Radix Astragali has The effects such as invigorating QI to consolidate the body surface resistance, diuretic detumescent, expelling pus and toxin by strengthening QI, granulation promoting；Rhizoma Cyperi dispersing the stagnated live-QI to relieve the stagnation of QI, regulating the flow of QI to ease the stomach, menstruction regulating and pain relieving；Three pairs of joints are clear Thermal detoxification, preventing the attack (or recurrence) of malaria, synthetism, expelling wind and removing dampness；Fructus Forsythiae heat clearing away, removing toxic substances, eliminating stagnation, detumescence；Rhizoma Atractylodis are drying damp and strengthening spleen, wind-damp dispelling, improving eyesight；Wear Heart grass heat-clearing and toxic substances removing, cough-relieving, pain relieving；Fructus Piperis Longi warming spleen and stomach for dispelling cold, therapeutic method to keep the adverse QI flowing downwards pain relieving；Herba Eupatorii has the work of antipyretic clearing away summer-heat, dispelling dampness to invigorate the stomach, preventing or arresting vomiting With；Gold lion rattan cures mainly heatstroke stomachache, stomachache, dysentery of suffering from abdominal pain, rheumatic arthritis, venom；Radix Peucedani has lowering the adverse-rising QI to resolve phlegm, dissipates wind Effect of heat clearing away；Herb Gynostemmae Pentaphylli replenishing QI to invigorate the spleen, preventing phlegm from forming and stopping coughing, heat-clearing and toxic substances removing；Radix Aconiti Lateralis Preparata recuperating depleted YANG and rescuing the patient from collapse, mend fire supporing yang, dispersing cold for relieving pain. Playing altogether eliminates the phlegm rush down turbid, promoting blood circulation to remove stagnancy, regulation blood fat effect.

The each raw material of the present invention also the embodiment of part by weight mixing can realize listed by according to the form below.Its processing technique and enforcement Example 1 is identical.(unit: weight portion)

Real Execute Example	Semen Cassiae Son	Radix Paeoniae Rubra	Herba Taxilli Raw	Rhizoma Chuanxiong	Stretch Muscle Grass	Folium Pyrrosiae	Radix Angelicae Sinensis	Motherwort Son	The Radix Astragali	Fragrant Attached	Three pairs Joint	Fructus Forsythiae	Rhizoma Atractylodis	Wear The heart Grass	Fructus Piperis Longi	Wear Blue	Gold lion Rattan	Radix Peucedani	Strand Stock Blue	Radix Aconiti Lateralis Preparata
																					Two	10	20	15	12	2	10	10	15	6	8	10	35	10	8	10	6	10	15	6	8
Three	15	15	20	10	4	6	15	10	12	6	15	30	15	6	15	4	15	10	8	6
																					Four	12	18	18	11	3	9	13	13	13	7	13	33	14	7	12	5	12	14	7	7

Physical data: 100 example hyperlipidemia cases, the maleest 76 people, female 24 people, age 39～59 years old, experimenter's blood fat raises, blood Cholesterol, triglyceride in liquid are above normal level.

Efficacy assessment standard: effective: lipids detection reaches following any one: T-CHOL (TC) declines >=20%, glycerol Three esters (TG) decline >=40%.Effective: lipids detection reaches following any one: T-CHOL (TC) decline>=10% but<20%, Triglyceride (TG) decline>=20% but<40%.Invalid: lipids detection is not up to above standard person.

Therapeutic Method: embodiment one medicament, is administered orally for 2 times, the most oral about 150ml, takes 50 altogether every day 1 dose point My god.

Test result: effective 78 examples, effective 19 examples, invalid 3 examples, total effective rate 97%.

Model case:

Ma, female, 52 years old, hyperlipidemia medical history 3 years, embodiment one medicament, every day 1 dose point was administered orally for 2 times, the most oral About 150ml, takes 40 days altogether, and before and after treatment, the change of lipids detection value is as follows: T-CHOL (TC) 3.62 → 3.21, glycerol three Ester (TG) 3.36 → 2.52, HDL-C (HDL-C) 0.92 → 1.20, low-density lipoprotein cholesterol (LDL- C) 1.89 → 1.85.

Striking so-and-so, man, 56 years old, hyperlipidemia medical history 5 years, be administered orally for 2 times every day 1 dose point, about 150ml be administered orally the most on an empty stomach, Taking altogether 50 days, before and after treatment, the change of lipids detection value is as follows: T-CHOL (TC) 4.78 → 4.15, triglyceride (TG) 2.17 → 1.65, HDL-C (HDL-C) 0.91 → 1.05, low-density lipoprotein cholesterol (LDL-C) 3.11 → 2.66。

Claims

1. the Chinese medicine composition treating hyperlipidemia, it is characterised in that be made up of the crude drug of following weight portion: Semen Cassiae 10 ～15 parts, Radix Paeoniae Rubra 15～20 parts, Herba Taxilli 15～20 parts, Rhizoma Chuanxiong 10～12 parts, Herba Lycopodii 2～4 parts, Folium Pyrrosiae 6～10 parts, Radix Angelicae Sinensis 10～15 parts, Fructus Leonuri 10～15 parts, the Radix Astragali 6～12 parts, Rhizoma Cyperi 6～8 parts, three to 10～15 parts of joint, Fructus Forsythiae 30～35 parts, grey Art 10～15 parts, Herba Canscorae 6～8 parts, Fructus Piperis Longi 10～15 parts, Herba Eupatorii 4～6 parts, gold lion rattan 10～15 parts, Radix Peucedani 10～15 parts, Herb Gynostemmae Pentaphylli 6～8 parts, Radix Aconiti Lateralis Preparata 6～8 parts, by medicinal for above-mentioned raw materials water soaking, filtrate of removing slag after decocting to obtain.