CN106075356A - 一种治疗溃疡性结肠炎的中药组合物 - Google Patents

一种治疗溃疡性结肠炎的中药组合物 Download PDF

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CN106075356A
CN106075356A CN201610598433.0A CN201610598433A CN106075356A CN 106075356 A CN106075356 A CN 106075356A CN 201610598433 A CN201610598433 A CN 201610598433A CN 106075356 A CN106075356 A CN 106075356A
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张志杰
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Abstract

本发明提供一种治疗溃疡性结肠炎的中药组合物，所述中药组合物由以下质量份数的各原料药组成：广藿香1‑3份、白头翁12‑16份、白术8‑10份、黄连1‑3份、干姜1‑3份、半夏4‑6份、肉桂4‑6份、杜仲1‑3份、石榴皮8‑12份、蒲公英3‑5份、黄芪4‑6份、桂枝4‑6份、陈皮2‑4份。本发明的中药组合物能够有效治疗溃疡性结肠炎，见效快，副作用小，停药后不容易复发，经352人试用，治愈260人，减轻73人，治愈率达74%以上，有效率可达95%以上。

Description

一种治疗溃疡性结肠炎的中药组合物
技术领域
本发明涉及一种治疗溃疡性结肠炎的中药组合物。
背景技术
结肠炎是指各种原因引起的结肠炎症性病变。主要临床表现腹泻、腹痛、黏液便及脓血便、里急后重、甚则大便秘结、数日内不能通大便；常伴有消瘦乏力等，多反复发作。根据不同病因，结肠炎可分为溃疡性结肠炎、缺血性结肠炎、伪膜性结肠炎等。现有的治疗溃疡性结肠炎的药物，多为西药，虽有一定疗效，但是副作用大，且停药后容易复发。
发明内容
为了解决现有技术中存在的问题，本发明提供了一种治疗溃疡性结肠炎的中药组合物；为此，本发明还提供其制备方法和应用。
本发明提供一种治疗溃疡性结肠炎的中药组合物，所述中药组合物由以下质量份数的各原料药组成：广藿香1-3份、白头翁12-16份、白术8-10份、黄连1-3份、干姜1-3份、半夏4-6份、肉桂4-6份、杜仲1-3份、石榴皮8-12份、蒲公英3-5份、黄芪4-6份、桂枝4-6份、陈皮2-4份。
作为优选，所述中药组合物由以下质量份数的各原料药组成：广藿香2份、白头翁14份、白术9份、黄连2份、干姜2份、半夏5份、肉桂5份、杜仲2份、石榴皮10份、蒲公英4份、黄芪5份、桂枝5份、陈皮3份。
本发明还提供上述中药组合物的制备方法，步骤如下：
（1）取配方量的广藿香、白头翁、白术、黄连、干姜、半夏、肉桂加8-12倍量的水先浸泡30-45分钟，再煎煮1-2次，每次30-45分钟，合并煎液，滤过，得到滤液A；
（2）将配方量的其余原料药粉碎成粗粉，加4-10倍质量70-95%乙醇，提取2-4次，每次1-2h，滤过，合并提取液，减压回收乙醇，得到滤液B；
（3）将滤液A和滤液B合并，浓缩至2倍量，使制剂内最终生药含量50%（即每1mL含生药0.5g），即得。
本发明还提供上述中药组合物在制备治疗溃疡性结肠炎的药物中的应用。
本发明的中药组合物能够有效治疗溃疡性结肠炎，见效快，副作用小，停药后不容易复发，经352人试用，治愈260人，减轻73人，治愈率达74%以上，有效率可达95%以上。
具体实施方式
以下的实施例便于更好地理解本发明，但并不限定本发明。下述实施例中的实验方法，如无特殊说明，均为常规方法。下述实施例中所用的试验材料，如无特殊说明，均为市售。
本发明的治疗溃疡性结肠炎的中药组合物由以下质量份数的各组分组成：
广藿香1-3份、白头翁12-16份、白术8-10份、黄连1-3份、干姜1-3份、半夏4-6份、肉桂4-6份、杜仲1-3份、石榴皮8-12份、蒲公英3-5份、黄芪4-6份、桂枝4-6份、陈皮2-4份。
本发明的治疗溃疡性结肠炎的中药组合物的制备方法为:
（1）取配方量的广藿香、白头翁、白术、黄连、干姜、半夏、肉桂加8-12倍量的水先浸泡30-45分钟，再煎煮1-2次，每次30-45分钟，合并煎液，滤过，得到滤液A；
（2）将配方量的其余原料药粉碎成粗粉，加4-10倍质量70-95%乙醇，提取2-4次，每次1-2h，滤过，合并提取液，减压回收乙醇，得到滤液B；
（3）将滤液A和滤液B合并，浓缩至2倍量，使制剂内最终生药含量50%（即每1mL含生药0.5g），即得。
每日两次，口服，每次服用量为100ml，5天为一个疗程。
实施例1
本发明的治疗溃疡性结肠炎的中药组合物由以下质量份数的各组分组成：
广藿香2份、白头翁14份、白术9份、黄连2份、干姜2份、半夏5份、肉桂5份、杜仲2份、石榴皮10份、蒲公英4份、黄芪5份、桂枝5份、陈皮3份。
本发明的治疗溃疡性结肠炎的中药组合物的制备方法为:
（1）取配方量的广藿香、白头翁、白术、黄连、干姜、半夏、肉桂加10倍量的水先浸泡40分钟，再煎煮1次，每次40分钟，合并煎液，滤过，得到滤液A；
（2）将配方量的其余原料药粉碎成粗粉，加6倍质量80%乙醇，提取3次，每次1.5h，滤过，合并提取液，减压回收乙醇，得到滤液B；
（3）将滤液A和滤液B合并，浓缩至2倍量，使制剂内最终生药含量50%（即每1mL含生药0.5g），即得。
实施例2
本发明的治疗溃疡性结肠炎的中药组合物由以下质量份数的各组分组成：
广藿香3份、白头翁12份、白术10份、黄连1份、干姜3份、半夏4份、肉桂6份、杜仲1份、石榴皮12份、蒲公英3份、黄芪6份、桂枝4份、陈皮4份。
本发明的治疗溃疡性结肠炎的中药组合物的制备方法为:
（1）取配方量的广藿香、白头翁、白术、黄连、干姜、半夏、肉桂加12倍量的水先浸泡30分钟，再煎煮2次，每次30分钟，合并煎液，滤过，得到滤液A；
（2）将配方量的其余原料药粉碎成粗粉，加10倍质量70%乙醇，提取2次，每次2h，滤过，合并提取液，减压回收乙醇，得到滤液B；
（3）将滤液A和滤液B合并，浓缩至2倍量，使制剂内最终生药含量50%（即每1mL含生药0.5g），即得。
实施例3
本发明的治疗溃疡性结肠炎的中药组合物由以下质量份数的各组分组成：
广藿香1份、白头翁16份、白术8份、黄连3份、干姜1份、半夏6份、肉桂4份、杜仲3份、石榴皮8份、蒲公英5份、黄芪4份、桂枝6份、陈皮2份。
本发明的治疗溃疡性结肠炎的中药组合物的制备方法为:
（1）取配方量的广藿香、白头翁、白术、黄连、干姜、半夏、肉桂加8倍量的水先浸泡45分钟，再煎煮1次，每次45分钟，合并煎液，滤过，得到滤液A；
（2）将配方量的其余原料药粉碎成粗粉，加4倍质量95%乙醇，提取4次，每次1h，滤过，合并提取液，减压回收乙醇，得到滤液B；
（3）将滤液A和滤液B合并，浓缩至2倍量，使制剂内最终生药含量50%（即每1mL含生药0.5g），即得。
最后应说明的是：以上所述仅为本发明的优选实施例而已，并不用于限制本发明，尽管参照前述实施例对本发明进行了详细的说明，对于本领域的技术人员来说，其依然可以对前述各实施例所记载的技术方案进行修改，或者对其中部分技术特征进行等同替换。凡在本发明的精神和原则之内，所作的任何修改、等同替换、改进等，均应包含在本发明的保护范围之内。

Claims (4)

1.一种治疗溃疡性结肠炎的中药组合物，其特征在于：所述中药组合物由以下质量份数的各原料药组成：广藿香1-3份、白头翁12-16份、白术8-10份、黄连1-3份、干姜1-3份、半夏4-6份、肉桂4-6份、杜仲1-3份、石榴皮8-12份、蒲公英3-5份、黄芪4-6份、桂枝4-6份、陈皮2-4份。
2.根据权利要求1所述的中药组合物，其特征在于：所述中药组合物由以下质量份数的各原料药组成：广藿香2份、白头翁14份、白术9份、黄连2份、干姜2份、半夏5份、肉桂5份、杜仲2份、石榴皮10份、蒲公英4份、黄芪5份、桂枝5份、陈皮3份。
3.权利要求1或2所述的中药组合物的制备方法，其特征在于：步骤如下：
（1）取配方量的广藿香、白头翁、白术、黄连、干姜、半夏、肉桂加8-12倍量的水先浸泡30-45分钟，再煎煮1-2次，每次30-45分钟，合并煎液，滤过，得到滤液A；
（2）将配方量的其余原料药粉碎成粗粉，加4-10倍质量70-95%乙醇，提取2-4次，每次1-2h，滤过，合并提取液，减压回收乙醇，得到滤液B；
（3）将滤液A和滤液B合并，浓缩至2倍量，使制剂内最终生药含量50%（即每1mL含生药0.5g），即得。
4.权利要求1或2所述的中药组合物在制备治疗溃疡性结肠炎的药物中的应用。
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