CN106074933A - A kind of Chinese medicine composition treating chronic atrophic gastritis - Google Patents

A kind of Chinese medicine composition treating chronic atrophic gastritis Download PDF

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CN106074933A
CN106074933A CN201610642127.2A CN201610642127A CN106074933A CN 106074933 A CN106074933 A CN 106074933A CN 201610642127 A CN201610642127 A CN 201610642127A CN 106074933 A CN106074933 A CN 106074933A
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atrophic gastritis
stomach
medicine
chronic atrophic
chinese medicine
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蓝国希
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/36Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage

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Abstract

The present invention discloses and a kind of makes for a kind of Chinese medicine composition treating chronic atrophic gastritis with five kinds of Chinese herbal medicine for raw material, it is characterized in that the powder that it is made up of the Chinese herbal medicine of following weight parts proportioning: Herba Lysimachiae 20, Radix Salviae Miltiorrhizae 16, Semen Vaccariae 12, Herba Taraxaci 12, Rhizoma Acori Graminei 8.

Description

A kind of Chinese medicine composition treating chronic atrophic gastritis
Technical field
The invention belongs to a kind of chronic gastritis technical field, be specifically related to make for controlling for raw material with five kinds of Chinese herbal medicine Treat the powder of chronic atrophic gastritis.
Background technology
Chronic atrophic gastritis is also referred to as atrophic gastritis, and with gastric epithelial and body of gland atrophy, number reduces, and gastric mucosa becomes Thin, mucosa basic unit thickens, or companion's gland metaplasia and intestinal gland metaplasia, or has the chronic digestible system disease that atypical hyperplasia is characterized Sick.Often show as epigastrium dull pain, distension, belch, inappetence, or become thin, anemia etc., without specificity.It is that one is caused a disease more Because of disposition disease and precancerous lesion, the symptom of atrophic gastritis, sign are without specificity, it is impossible to as the foundation of diagnosis, make a definite diagnosis master Gastroscope to be leaned on and gastric mucosa living tissue pathologic finding.Seen under gastroscope, 1. gastric mucosa color is thin out;2. under mucosa, blood vessel sees through;③ Duplicature is tiny even to disappear;4. when atrophic gastritis is with body of gland cervical region hyperplasia or intestinal epithelial metaplasia, mucous membrane surface Rough, it is in granular form or nodositas, it is seen that pseudopolyp is formed;5. atrophy mucosa fragility increases, the most hemorrhage, and can have erosion Stove;6. atrophic gastritis can be simultaneously with the performance of chronic superficial gastritis, such as congested erythema, attachment mucus, and reflective increasing Strong etc..
Pathologic finding is visible: 1. intrinsic in gastric mucosa body of gland atrophy;2. metaplasia;3. hypertrophy;4. canceration.
Doctor trained in Western medicine clinical treatment includes: smoking cessation is given up alcohol, it is to avoid use the medicine of infringement gastric mucosa, the suitable rule of diet, it is to avoid mistake Hot, over-salty and maror, the chronic mouth of active treatment, nose, pharyngeal infection focus;Low acid is confirmed through pentagastrin test determination Or anacidity patient takes rice vinegar in right amount, also there are selection polyzyme tablets or pancreatin tablets treatment, to improve indigestion symptom;To pylorus spiral shell The positive Anti-Helicobacter Pylori Therapy of patient that bacillus detection is positive;Suppress bile reflux and improve gastric motility, preventing bile reflux, Regulation and recovery gastrointestinal motility;Increase mucosal nutrition, improve Gastric Mucosal Cells regeneration capacity, strengthen the gastric mucosa opposing to gastric acid Ability, reaches to protect gastric mucosa effect;To low acid anacidity or have the patients with atrophic gastritis of corpus atrophy that pentapeptide stomach can be used to secrete Element etc..
Chronic atrophic gastritis, is the pathological diagnosis title of modern medicine.Its clinical manifestation, is with gastral cavilty feeling of fullness distending pain, The General Symptomies the such as with the passing of time course of disease delays, and touching difficulty heals, emaciated physique are main disease, belong to " stomach painful abdominal mass " and " gastral cavilty in Chinese medicine Category bitterly ".Atrophic gastritis is more common in middle-older patient, the body of gland atrophy of stomach, and gastric acid and pepsinia all reduce, very To entirely without free acid, its mechanism and traditional Chinese medical science deficiency of stomach-Yin, body fluid shortage communicates.Therefore deficiency of stomach-Yin is chronic atrophic gastritis Basic place.In concrete clinical practice, due to deficiency of QI in middle-JIAO, Deficiency and coldness of spleen and stomach, stagnation of QI due to depression of the liver, blood stasis network is stagnant, damp and hot retardance Person is the most not within minority, and existing data shows, chronic atrophic gastritis is by following eight type determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs:
Type of deficiency of stomach yin, rules it by law with stomach reinforcing yin nourishing: stomach is the foundation of acquired constitution, barn organs, reservoir of food and drink.There is gastric qi then Raw, extreme hypofunction of the stomach is the most dead.And the power of gastric qi is closely related with stomach-Yin, when stomach-Yin is sufficient, stomach just can be able to along fall, can metaplasia water Paddy, and the defeated body fluid of transporting essential substances in solution.If deficiency of stomach-Yin, visible clinically indigestion and loss of appetite do not change, gastral cavilty feeling of fullness, noisy do not relax, such as burn feeling; Hungry and loss of appetite, eats then gastral cavilty distension, the most then has a pain;Body fluid cannot flow upwards then dry mouth and tougue, liquid executes down then constipation due to dry stool;The deficiency of YIN Interior-heat is the most vexed sleeps less, feverish sensation in the palms and soles, the few Tianjin of red tongue yellow fur, stringy and thready pulse or stringy and rapid pulse.Based on stomach reinforcing yin nourishing on Zhi Liao.
Deficiency of QI in middle-JIAO type, rules it by law with invigorating the spleen and replenishing QI: at the beginning of atrophic gastritis morbidity, insufficiency of stomach spleen weak person is few, in after Phase, along with the development of the state of an illness, gastropathy and spleen, deficiency of YIN affecting YANG, the card of deficiency of QI in middle-JIAO often occur.Seeing gastral cavilty feeling of fullness clinically, food is received The best, glutted discomfort after feed, belch, body is tired weak, and big loose stool is thin or matter is soft shapeless, emaciated physique or with slight floating Swollen, pale tongue, white and thin fur, deep,thready and forceless pulse or heavy weak.Based on invigorating the spleen and replenishing QI on Zhi Liao.
Spleen-stomach deficiency-cold, rules it by law with warming YANG to expel cold: patients with atrophic gastritis, and from the beginning of with the deficiency of YIN for many, mid-term gradually occurs Deficiency of vital energy person, controls if with the passing of time losing, then transporting is unable, deficiency of both QI and blood, causes yang deficiency, pain when seeing gastral cavity abdomen feeling of fullness clinically, desire for warm and being pressed, The alleviation of pain pressed, anorexia, lusterless complexion, emaciated physique, loose stool or dilute, pale tongue, white and thin fur, deep-thready pulse etc..If can hold concurrently the most again There are the insufficiency of kidney-YANG symptoms such as soreness of the waist and knees, dizziness, forgetful, fear of cold is afraid of cold.The gastroscopy of this class patient, mostly is severe atrophic Gastritis, the many changes in severe atrophy of gastric mucosa.Based on warming YANG to expel cold method on Zhi Liao.
Caused by hepatic stagnation qi stagnation, rules it by law by depressed liver-energy dispersing and QI regulating: stomach is the mansion of the development of evil in febrile disease, with logical reduce to suitable.So the property of its logical fall needs again The normal free flow of qi of irritability just can complete, if irritability stasis, perverse and unreasonable manner violates stomach, then cause obstruction of QI, formed the stagnation of QI, food stagnation, All diseases such as dampness, fire stagnation, blood stasis, the most common swollen to the gastral cavity abdomen side of body, meet anger what for, have a dizzy spell, bitter taste xerostomia, indigestion and loss of appetite be not intended to Eating, singultus is not relaxed, constipation, yellow urine, dimly red tongue, yellow and greasy fur, deep and stringy pulse or stringy and thready pulse.On Zhi Liao with depressed liver-energy dispersing and QI regulating method it is Main.
Adverse rising of stomach-QI type, rules it by law with regulating the stomach and sending down the abnormal ascending QI: stomach is the internal organs of water paddy, six internal organs person's excreting foodstuff instead of storing essence, therefore to lead to is With, suitable to reduce to, fall then and, do not drop the most stagnant, anti-rise and be inverse.WEIDE is to drop, and water paddy can normally be become thoroughly decomposed, and waste matter can normally be arranged Go out, if gastric qi lose in and fall, block in, then gastral cavilty feeling of fullness distending pain, singultus takes place frequently, the most then vomiting, indigestion and loss of appetite, constipation, the dark tongue of tongue Yellow greasy, stringy and thready pulse.Based on regulating the stomach and sending down the abnormal ascending QI method on Zhi Liao.
Obstruction of collaterals by blood stasis type, rules it by law with blood circulation promoting and blood stasis dispelling: typically just onset is at edema caused by disorder of QI, based on swollen, the most then for atrophic gastritis Blood stasis resistance network, based on pain.Clinical observation is not healed to atrophic gastritis is prolonged, can have the change of blood stasis.Cause the reason of blood stasis: one For depression of liver-QI, qi depression to blood stasis;Two is pathogen usually intruding into collateral in protracted disease;Three is deficiency of stomach-Yin, and heat-transformation network is hindered, and blood clotting amasss as the stasis of blood.Clinical manifestation is Gastral cavilty twinge, fixes and does not moves, and tongue is dark red or there are petechia, yellow and thin fur, deep and hesitant pulse in tongue limit.It is main for controlling with blood circulation promoting and blood stasis dispelling.
In humidity hysteresis, burnt type, rules it by law by clearing away heat and eliminating dampness: spleen preferring dryness to dampness, stomach liking moistness and disliking dryness, and both interact, to maintain The defeated cloth of water liquid runs.If eating cold and uncooked food excessively or insobriety, can impairing the spleen and stomach, cause retention of water-damp in the body, long Yu Huare and burnt in blocking. Clinical manifestation is gastral cavilty feeling of fullness or vexed pain, painful abdominal mass plug between breast, belch, bitter taste, the most do not think drink, sticky or halitosis in mouth, big loose stool or Not well, yellow urine, tongue is dark red, and the dirty greasy Huang of tongue is thick or the most greasy.It is main for controlling by clearing away heat and eliminating dampness.
Resistance type in food stagnation, with the stagnant ruling by law of removing food stagnancyization it: in clinic, many atrophic gastritis are due to eating and drinking without temperance, hungry full nothing Degree, crosses and eats the product of wine meat frying and cause, and this stops long-pending middle burnt caused for diet, treats the method for fooled food stagnation removing, its type feature table Being now feeling of oppression and fullness in the chest and epigastrium, pain when gastral cavity is swollen, belching and acid regurgitation, it is indigestion and loss of appetite to dislike food, or diarrhea with loose stool, and yellow fur is thick and greasy, deep-rolling pulse or stringy and rolling pulse. It is main for controlling by the stagnant method of removing food stagnancyization.
In above-mentioned various therapeutic scheme, western medical treatment is suited the medicine to the illness, and effect certainly but the most repeatedly, do not heal by protracted inflammation, causes suffering from Person is to curing ungodliness.Data shows according to statistics, uses above-mentioned classification therapy, and tcm clinical practice therapeutic effect is good, but all according to clinical Disease determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, the performance of some patient and his family's diseases is the most typical, and medication is relative complex, curative effect short-term is inconspicuous, and needing of having is long Phase such as takes medicine at the shortcoming.
Summary of the invention:
The purpose of the present invention is aiming at the cause of disease and the tcm clinical practice feature of chronic atrophic gastritis, is inheriting motherland's medical science Rarity on the basis of, sum up out according to inventor's clinical practice for many years, this Chinese medicine composition be used for chronic atrophic gastritis, tool There is the feature that medication is simple, clinical application takes effect in early days, medicine time is short
The technical solution of the present invention is: a kind of Chinese medicine for treating chronic tracheitis, it is characterised in that it be by The Chinese herbal medicine of following weight parts proportioning is made:
Herba Lysimachiae 20 Radix Salviae Miltiorrhizae 16 Semen Vaccariae 12 Herba Taraxaci 12 Rhizoma Acori Graminei 8, treatment chronic atrophic gastritis is to take Stating medical herbs, with gram as mass unit, grind to the powder altogether, load capsule for medicine, every weight 0.4 gram, each serving 2-3 grain, three times a day.
The important feature of the present invention be the Clinical pharmacological efficiency that had of nutritional labeling abundant in medicament, each composition and Function cures mainly as follows:
Herba Lysimachiae: Herba Lysimachiae: another name Herba Lysimachiae, Lysimachia christinae Hance, artificial flower are raw, main product in Yangtze River in China basin, Herba Lysimachiae Sweet in the mouth, salty, cold nature.Enter liver, gallbladder, kidney, bladder warp.Modern medicine study shows, Herba Lysimachiae has promotion bile secretion and excretion Effect, can relax bile duct sphincter, makes the muddy stone formed in bile duct be prone to discharge, thus reduces the stifled of bile duct Plug and pain, make jaundice disappear.Tcm clinical practice is summed up, and Herba Lysimachiae is the good medicine of the antipyretic infantile malnutrition that disappears, and has heat-clearing and toxic substances removing, clear dampness removing Heat, promoting blood circulation to remove blood stasis, the effect such as jaundice eliminating function of gallbladder promoting, can be used for wet disease etc..
Radix Salviae Miltiorrhizae: call blood red wood, Arisaema balansae Engl. etc., main product Sichuan Province China, Henan etc., there is cultivation in major part province.This medical herbs taste Hardship, cold nature.Enter the heart, Liver Channel.Modern medicine study shows, this medicine can protect the liver and adjust vivo immunization function, promotes injured group Knit the pharmacological actions such as reparation and regeneration.Tcm clinical practice is summed up, and Radix Salviae Miltiorrhizae is the good medicine of blood circulation promoting and blood stasis dispelling, has blood circulation promoting and blood stasis dispelling, and removing heat from blood disappears Swollen effect, can be used for the diseases such as abdominalgia with blood stasis.
Semen Vaccariae: another name does not stay row, wheat Lan Zi etc., and main product is in Jiangsu Province, China, Hebei, Henan and Shaanxi etc..This medical herbs Bitter in the mouth, property is put down.Enter liver, stomach warp.Modern medicine study shows, Semen Vaccariae has analgesic Clinical pharmacological efficiency.Tcm clinical practice Summing up, Semen Vaccariae is the good medicine that promoting the circulation of blood is stimulated the menstrual flow, and has and invigorates blood circulation, and the effect stimulated the menstrual flow can be used for the pain of tcm clinical practice.
Herba Taraxaci: another name Herba crotalariae albidae, milk Herba Leptochloae Chinensis etc., has cultivation all over China.This medical herbs sweet-bitter flavor, cold in nature, enter liver, Stomach, kidney channel.Modern medicine study shows, Herba Taraxaci powder has choleretic effect, can substantially subtract through stomach caused by factor stress be waited to stick Membrane damage, makes ulcer rates and ulcer index be decreased obviously, has the pharmacological action of stomach invigorating, building body simultaneously.TCM Bed is summed up, and Herba Taraxaci is the good medicine of heat-clearing and toxic substances removing, has the effects such as heat-clearing and toxic substances removing, dampness removing stomach invigorating.Can be used for the treatment of gastritis.
Rhizoma Acori Graminei: another name RHIZOMA ACORI TATARINOWII, stone Scolopendra etc., is distributed in each provinces and regions on the south China the Yellow River.This medical herbs acrid in the mouth, hardship, property Temperature, enters the heart, stomach.Modern medicine study shows, Rhizoma Acori Graminei powder energy facilitating digestion liquid is secreted, and prevents gastrointestinal abnormal fermentation and has pine The Clinical pharmacological efficiency of relaxation intestinal tube smooth muscle spasm;Additionally, also have the functions such as cooling, sterilization.Tcm clinical practice is summed up, and Rhizoma Acori Graminei is Have one's ideas straightened out the good medicine dried, there is the effects such as removing dampness appetizing, can be used for gastral cavity painful abdominal mass the most hungry, the diseases such as mouthful dysentery of keeping silent.
Example:
Patient's Wei, female, 55 years old, south of the River township of Dahua Yao Nationality Autonomous County central primary school teacher.Gastralgia recurrent exerbation is 3 years, in acupuncture sample, time be dull pain, after food, distension is had a pain, usually abdominal distention, accompany pantothenic acid, heartburn, belch, xerostomia desire for hot drinks, stool Shi Gan, successively does gastroscopy and pathological biopsy three times, is diagnosed as chronic atrophic gastritis.Red tongue with thin and yellow fur, stringy and thready pulse.Then Take: Herba Lysimachiae 20 grams, Radix Salviae Miltiorrhizae 16 grams, Semen Vaccariae 12 grams, Herba Taraxaci 12 grams, Rhizoma Acori Graminei 8 grams, doctor's advice patient and his family, take above-mentioned medical herbs, Grinding to the powder altogether, load capsule for medicine, every weight 0.4 gram, each serving 3-4 grain, three times a day.After one month, symptom substantially alleviates.

Claims (1)

1. the invention belongs to one and treat chronic gastritis technical field, be specifically related to five kinds of Chinese herbal medicine for raw material make for The powder for the treatment of chronic atrophic gastritis, it is characterised in that it is made up of the Chinese herbal medicine of following weight parts proportioning: Herba Lysimachiae 20, Radix Salviae Miltiorrhizae 16, Semen Vaccariae 12, Herba Taraxaci 12, Rhizoma Acori Graminei 8.
CN201610642127.2A 2016-08-08 2016-08-08 A kind of Chinese medicine composition treating chronic atrophic gastritis Pending CN106074933A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1100651A (en) * 1994-03-15 1995-03-29 广东医学院医药科技开发中心 Chinese herbal prepn. for curing chronic gastroenteritis and peptic gastric ulcer
CN1676137A (en) * 2003-12-23 2005-10-05 李克成 Sichuan China berry anti-inflammation oral liquor
CN102178887A (en) * 2011-05-16 2011-09-14 汤炳显 Traditional Chinese medicine for treating gastropathy
CN105106840A (en) * 2015-08-20 2015-12-02 登封市科创商务咨询有限公司 Pain-relieving inflammation-diminishing vomiting-arresting decoction

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1100651A (en) * 1994-03-15 1995-03-29 广东医学院医药科技开发中心 Chinese herbal prepn. for curing chronic gastroenteritis and peptic gastric ulcer
CN1676137A (en) * 2003-12-23 2005-10-05 李克成 Sichuan China berry anti-inflammation oral liquor
CN102178887A (en) * 2011-05-16 2011-09-14 汤炳显 Traditional Chinese medicine for treating gastropathy
CN105106840A (en) * 2015-08-20 2015-12-02 登封市科创商务咨询有限公司 Pain-relieving inflammation-diminishing vomiting-arresting decoction

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