CN106074859A - A kind of oral traditional Chinese medicine composition treating poliosis - Google Patents

A kind of oral traditional Chinese medicine composition treating poliosis Download PDF

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Publication number
CN106074859A
CN106074859A CN201610646252.0A CN201610646252A CN106074859A CN 106074859 A CN106074859 A CN 106074859A CN 201610646252 A CN201610646252 A CN 201610646252A CN 106074859 A CN106074859 A CN 106074859A
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parts
chinese medicine
radix
medicine composition
traditional chinese
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CN201610646252.0A
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李云娟
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Chengdu Jiadi Lu Sha Biotechnology Co Ltd
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Chengdu Jiadi Lu Sha Biotechnology Co Ltd
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Priority to CN201610646252.0A priority Critical patent/CN106074859A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/39Convolvulaceae (Morning-glory family), e.g. bindweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/43Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/487Psoralea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Abstract

The invention discloses a kind of oral traditional Chinese medicine composition treating poliosis, it is characterized in that, be mainly made up of the raw material of Chinese medicine of following weight portion: 35 55 parts of Radix Rehmanniae Preparata, Fructus Lycii 20 80 parts, Radix Angelicae Sinensis 5 20 parts, 20 60 parts of Poria, Semen Cuscutae 20 80 parts, Radix Polygoni Multiflori 20 60 parts, Fructus Psoraleae 5 20 parts, Semen Sesami Nigrum 20 80 parts, Radix Achyranthis Bidentatae 20 40 parts.The Chinese prescription of the present invention, therapeutic effect is good, and efficiency is high, has no side effect and untoward reaction.

Description

A kind of oral traditional Chinese medicine composition treating poliosis
Technical field
The present invention relates to technical field of Chinese medicines, specifically refer to a kind of oral traditional Chinese medicine composition treating poliosis.
Background technology
The traditional Chinese medical science is thought, heat in blood, kidney qi are weak, the weak reason being all to cause poliosis of QI and blood.The source of nutrition of hair in blood, If hair bleaches or comes off, being mostly because deficiency of liver-blood, kidney qi is weak.Therefore, the Therapeutic Method of the traditional Chinese medical science is tonifying liver blood, benefit Kidney qi.Theory of Chinese medical science is: " liver storing blood, hair is the sign of blood condition ", " kidney controlling essence storage, its Hua Fa ", " heart governing blood and vessels ", " lung Main fur "." spleen is source of generating QI and blood ".That is the growth of hair and color and luster change, and the function prosperity and decline of the vital organs of the human body, Yang-energy essence and blood warm is moistened foster closely bound up.If internal organs function is vigorous, yang-energy essence and blood fills, and hair is fully moistened supports the most black profit Beautiful, it is difficult to depigmentation.On the contrary, if congenital defect, losing the day after tomorrow and support, internal organs function is weak, and negative and positive of qi and blood virtual loss is difficult hair of supplementing nutrition Then poliosis is the most raw, sparse easy to break.And wherein with spleen, kidney, liver relation the closest.All congenital defects, deficiency of kidney-essence, marrow lose less The person of filling, or irascible temperament, heat in blood are contained partially, impairment of YIN hematozemia person, or sorrow is pondered over, dysfunction of the spleen in transportation, QI and blood weary source person, or troubled Degree, insomnia and dreamful sleep, liver blood secretly consumption person, all can injure the five internal organs, deficient QI and blood, makes hair lose and supports and early white.
Existing commercially, yet there are no treatment poliosis oral traditional Chinese medicine composition.
Summary of the invention
The invention reside in a kind of therapeutic effect of offer good, efficiency is high, the Chinese medicine for oral administration group of the treatment poliosis having no side effect Compound.
The present invention is achieved through the following technical solutions: a kind of oral traditional Chinese medicine composition treating poliosis, mainly by following heavy The raw material of Chinese medicine composition of amount part: a kind of oral traditional Chinese medicine composition treating poliosis, mainly by the raw material of Chinese medicine group of following weight portion Become: Radix Rehmanniae Preparata 35-55 part, Fructus Lycii 20-80 part, Radix Angelicae Sinensis 5-20 part, Poria 20-60 part, Semen Cuscutae 20-80 part, Radix Polygoni Multiflori 20-60 Part, Fructus Psoraleae 5-20 part, Semen Sesami Nigrum 20-80 part, Radix Achyranthis Bidentatae 20-40 part.
In order to the present invention is better achieved, further, 40 parts of Radix Rehmanniae Preparata, Fructus Lycii 50 parts, Radix Angelicae Sinensis 30 parts, Fu by weight Siberian cocklebur 30 parts, Semen Cuscutae 30 parts, Radix Polygoni Multiflori 50 parts, Fructus Psoraleae 30 parts, Semen Sesami Nigrum 50 parts, Radix Achyranthis Bidentatae 30 parts.
In order to the present invention is better achieved, further, its dosage form is oral liquid, granule, tablet, capsule, ball Agent or powder.
In order to the present invention is better achieved, further, its dosage form is granule.
The preparation method of the oral traditional Chinese medicine composition of above-mentioned treatment poliosis, the dosage form of this prescription described is granule, Its method comprises the following steps:
1) by 40 parts of the Radix Rehmanniae Preparata of weight portion, Fructus Lycii 50 parts, Radix Angelicae Sinensis 30 parts, 30 parts of Poria, Semen Cuscutae 30 parts, Radix Polygoni Multiflori 50 parts, mend Bone fat 30 parts, Semen Sesami Nigrum 50 parts, Radix Achyranthis Bidentatae 30 parts are cleaned, and join in multi-function extractor and decoct three times, filter, and merge filter Liquid;
2) filtrate of upper step is heated the thick paste that relative density when being concentrated into 60 DEG C is 1.27-1.33 and obtains extractum;
3) extractum and pharmaceutic adjuvant are mixed and made into oral liquid, granule, capsule, pill or powder.
Wherein, decocting the soak by water that includes for three times adding for the first time 10 times amount 2 hours, the soak by water 1 that second time adds 8 times amount is little Time, third time adds the soak by water 1 hour of 6 times amount.
The present invention compared with prior art, has the following advantages and beneficial effect:
The Chinese prescription of the present invention, therapeutic effect is good, and efficiency is high, has no side effect and untoward reaction.
Detailed description of the invention
The present invention is expanded on further below in conjunction with specific embodiment, it should be appreciated that embodiment be merely to illustrate the present invention and not For limiting the scope of the invention.
Embodiment 1:
For treating the Chinese prescription of diabetes, be mainly made up of the raw material of Chinese medicine of following weight: 40 parts of Radix Rehmanniae Preparata, Fructus Lycii 50 parts, Radix Angelicae Sinensis 30 parts, 30 parts of Poria, Semen Cuscutae 30 parts, Radix Polygoni Multiflori 50 parts, Fructus Psoraleae 30 parts, Semen Sesami Nigrum 50 parts, Radix Achyranthis Bidentatae 30 parts.
The preparation method of the above-mentioned Chinese prescription for treating diabetes, the dosage form of this prescription described is granule, Its method comprises the following steps:
1) by 40 parts of the Radix Rehmanniae Preparata of weight portion, Fructus Lycii 50 parts, Radix Angelicae Sinensis 30 parts, 30 parts of Poria, Semen Cuscutae 30 parts, Radix Polygoni Multiflori 50 parts, mend Bone fat 30 parts, Semen Sesami Nigrum 50 parts, Radix Achyranthis Bidentatae 30 parts are cleaned, and join in multi-function extractor and decoct three times, filter, and merge filter Liquid;
2) filtrate of upper step is heated the thick paste that relative density when being concentrated into 60 DEG C is 1.27-1.33 and obtains extractum;
3) extractum and pharmaceutic adjuvant are mixed and made into oral liquid, granule, capsule, pill or powder.
Wherein, decocting the soak by water that includes for three times adding for the first time 10 times amount 2 hours, the soak by water 1 that second time adds 8 times amount is little Time, third time adds the soak by water 1 hour of 6 times amount.
By step 2) extractum and adjuvant dextrin press the weight ratio mix and blend of 1:2, pelletize, granulate, prepare granule, loading Dress, prepares granule.Every bag of 3g Han extractum.
Embodiment 2:
Poliosis patient 100 example, is randomly divided into 2 groups.Treatment group 30 example, male 11 examples, female 19 example, age 37-70 year, the mean age 56.5 years old, course of disease 0.5-9;Matched group 30 example, male 14 examples, female 16 example, age 33-68 year, 54.5 years old mean age, course of disease 1- 9.5 year.There is not significant difference between two groups of Genders, age, courses of disease, there is comparability.
Diagnostic criteria:
In hair, hair color becomes poliosis, gets rid of the poliosis caused by senile naturally-aged or ethnicity poliosis, but some is hereditary Property in one's early years poliosis caused by sexual factor or pathogenic factor.
Therapeutic Method
Treatment group takes the granule that the present invention prepares according to specific embodiment 1, and every bu morning, noon and afternoon take for three times.
All treat 2 weeks for two groups.
Points for attention: in drug administration process, all patients are it should be noted that diet care, and diet is regular, the most quantitatively, Eat pungent, fertile, sweet thing less, the food lit a fire such as Carnis caprae seu ovis, Carnis Canitis, beef, Carnis Sus domestica etc.;Perfumery: as Rhizoma Zingiberis Recens, Herba Alii fistulosi, Pericarpium Zanthoxyli, Fructus Capsici etc.;Stimulating food: Cyprinus carpio, Carassius auratus, Fructus Cucurbitae moschatae;Avoid the product of Radix Raphani, tobacco and wine.Polyphagia vegetable and fruit, with Brassica oleracea L.var.capitata L., Semen Sesami Nigrum, Semen arachidis hypogaeae, The foods such as mushroom, Citrus chachiensis Hort., Semen Glycines, fructus zizaniae caduciflorae, Semen Juglandis, Thallus Laminariae (Thallus Eckloniae), Auricularia, Semen sojae atricolor.
Evaluation criteria:
Curing: after 1 course for the treatment of, poliosis disappears, and grows hair color;
Effective: after 1 course for the treatment of, poliosis quantity reduces, and hair color grows more than 30%;
Invalid: after 1 course for the treatment of, poliosis does not reduce, and hair color does not grow.
Curative effect
After treating 2 weeks, treatment group patient reaches 42 examples of clinic control, effective 25 examples, and take a turn for the better 12 examples, invalid 5 examples;Matched group Reaching 30 examples of clinic control, effective 16 examples, take a turn for the better 3 examples, invalid 11 examples.It is poor to there is significant statistics in two groups of total effective rates Different, P < 0.05, the curative effect for the treatment of group is substantially better than matched group.
Embodiment 3:
Classical case:
King so-and-so, 18 years old, private prosecution started to occur as soon as a small amount of poliosis for 14 years old, along with the increase poliosis increasing number at age, and full head Diffusivity distribution poliosis accounts for 50%.Take medicine of the present invention whole blackening of root of hair after month, and start to grow hair color, continue clothes With 2 months, poliosis disappeared, and follows up a case by regular visits to not recur so far.
Huang, man, 16 years old, teen-ager leukotrichia, private prosecution often had a headache, and insomnia and dreamful sleep, hypomnesis, red tongue tongue is few, poliosis Account for 30%, take medicine of the present invention whole blackening of root of hair after month, and start to grow hair color, continue to take 2 months, Poliosis disappears, and follows up a case by regular visits to not recur so far.
Visible, the present invention treats the Chinese medicine composition of poliosis and achieves unexpected technique effect, has treatment time Unique advantages such as short, cure rate is high, medical material consumption is few, have preferable medical science promotional value.
Although an embodiment of the present invention has been shown and described, it will be understood by those skilled in the art that: not Depart from and these embodiments can be carried out multiple change under the principle of the present invention and objective, revise, replace and modification, the present invention's Scope is limited by claim and equivalent thereof.

Claims (4)

1. the oral traditional Chinese medicine composition treating poliosis, it is characterised in that be mainly made up of the raw material of Chinese medicine of following weight portion: Radix Rehmanniae Preparata 35-55 part, Fructus Lycii 20-80 part, Radix Angelicae Sinensis 5-20 part, Poria 20-60 part, Semen Cuscutae 20-80 part, Radix Polygoni Multiflori 20-60 part, benefit Bone fat 5-20 part, Semen Sesami Nigrum 20-80 part, Radix Achyranthis Bidentatae 20-40 part.
A kind of oral traditional Chinese medicine composition treating poliosis the most according to claim 1, it is characterised in that main by following heavy Amount part raw material of Chinese medicine composition: 40 parts of Radix Rehmanniae Preparata, Fructus Lycii 50 parts, Radix Angelicae Sinensis 30 parts, 30 parts of Poria, Semen Cuscutae 30 parts, Radix Polygoni Multiflori 50 parts, Fructus Psoraleae 30 parts, Semen Sesami Nigrum 50 parts, Radix Achyranthis Bidentatae 30 parts.
3. according to the arbitrary described a kind of oral traditional Chinese medicine composition treating poliosis of claim 1 or 2, it is characterised in that its system Agent form is oral liquid, granule, tablet, capsule, pill or powder.
A kind of oral traditional Chinese medicine composition treating poliosis the most according to claim 3, it is characterised in that its dosage form is Granule.
CN201610646252.0A 2016-08-09 2016-08-09 A kind of oral traditional Chinese medicine composition treating poliosis Withdrawn CN106074859A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107007745A (en) * 2017-05-16 2017-08-04 朱时祥 A kind of medicine of black hair and preparation method thereof and its application method
CN108057091A (en) * 2017-04-20 2018-05-22 刘建华 A kind of Chinese medicine hair-blackening formula and preparation method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108057091A (en) * 2017-04-20 2018-05-22 刘建华 A kind of Chinese medicine hair-blackening formula and preparation method
CN107007745A (en) * 2017-05-16 2017-08-04 朱时祥 A kind of medicine of black hair and preparation method thereof and its application method

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