CN106073782A - A kind of binder type liver magnetic resonance elastogram device - Google Patents

A kind of binder type liver magnetic resonance elastogram device Download PDF

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Publication number
CN106073782A
CN106073782A CN201610525294.9A CN201610525294A CN106073782A CN 106073782 A CN106073782 A CN 106073782A CN 201610525294 A CN201610525294 A CN 201610525294A CN 106073782 A CN106073782 A CN 106073782A
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CN
China
Prior art keywords
magnetic resonance
mechanical wave
processing unit
stimulation instrument
monitoring device
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Pending
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CN201610525294.9A
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Chinese (zh)
Inventor
邵晓宁
程敬亮
杨子涛
高雪梅
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First Affiliated Hospital of Zhengzhou University
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First Affiliated Hospital of Zhengzhou University
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Priority to CN201610525294.9A priority Critical patent/CN106073782A/en
Publication of CN106073782A publication Critical patent/CN106073782A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Detecting, measuring or recording devices for evaluating the respiratory organs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/42Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • A61B5/4222Evaluating particular parts, e.g. particular organs
    • A61B5/4244Evaluating particular parts, e.g. particular organs liver
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813Specially adapted to be attached to a specific body part
    • A61B5/6823Trunk, e.g., chest, back, abdomen, hip
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683Means for maintaining contact with the body
    • A61B5/6831Straps, bands or harnesses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • Physiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Signal Processing (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Psychiatry (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

Basis is the most novel relates to a kind of binder type liver magnetic resonance elastogram device, it is characterised in that include mechanical wave stimulation instrument, respiration monitoring device, conventional MR imaging apparatus and timer.MR imaging apparatus comprises signal processing unit, graphics processing unit and display.Respiration monitoring device is used for monitoring person under inspection and breathes, magnetic resonance pulse signal is triggered mutually in fixing respiratory period, after magnetic resonance pulse signal sends, mechanical wave stimulation instrument produces shearing wave and acts on experimenter's liver, again by signal processing unit record and calculate particle displacement situation, calculate and space orientation through graphics processing unit again, generate liver magnetic resonance elastic graph, whole during realized MR imaging apparatus and mechanical wave stimulation instrument and the synchronizing information of respiration monitoring device by timer.The present invention can generate the resonance elastic diagram of patient's liver, and the diagnosis especially hepatic fibrosis liver cirrhosis of hepatic disease is had great importance.

Description

A kind of binder type liver magnetic resonance elastogram device
Technical field
The present invention relates to medical imaging technology field, be specifically related to a kind of binder type liver magnetic resonance elastogram device, Be conducive to patients with liver diseases condition-inference and pathological stage of fibrosis.
Background technology
Magnetic resonance elastography (MRE) is the new technique grown up on the basis of conventional MRI imaging, is a kind of Mechanization, the palpation means of quantification, have objective, resolution is high, noinvasive, not by the advantage that limited of diagnosis position.MRE can lead to Crossing mechanical wave quantitative measurement tissue elasticity or hardness, liver MRE develops rapidly in terms of the Noninvasive diagnosis of hepatic fibrosis, is recognized For being the diagnostic method of the most most prospect.But, the design of liver magnetic resonance elastogram device is the most immature, present document relates to A kind of binder type liver magnetic resonance elastogram device.
Summary of the invention
In order to solve defect and problem present in above-mentioned prior art, the present invention proposes a kind of binder type liver magnetic resonance Elastogram device, it is possible to liver carries out magnetic resonance elastography, and monitors patient respiration, generates the magnetic resonance of patient's liver Elastic graph, for the technological means that the diagnosis offer of hepatic disease is new.
The present invention is achieved by the following technical solutions:
Including mechanical wave stimulation instrument, respiration monitoring device, magnetic resonance equipment and timer, described magnetic resonance equipment includes letter Breath processing unit, graphics processing unit and display, wherein said mechanical wave stimulation instrument is connected with signal processing unit, described Graphics processing unit carries out calculating for the data that transmitted by signal processing unit and space orientation generating is organized by inspection The spatial distribution map of internal coefficient of elasticity, described display shows for the view data transmitted by graphics processing unit Over the display, described timer respectively with mechanical wave stimulation instrument, respiration monitoring device, signal processing unit, image procossing list Unit is connected with display, for synchronization mechanism ripple stimulation instrument and magnetic resonance equipment so that mechanical wave stimulation instrument, monitoring of respiration fill Put, signal processing unit, graphics processing unit time-sharing work, synchronizing information, described mechanical wave stimulation instrument still further comprises control Panel processed and mechanical wave generating means, wherein control panel is positioned at equipment room, is used for regulating mechanical wave frequency and intensity, mechanical wave Generating means is fixed on bellyband, acts on human body epigastrium surface, transmits mechanical wave to human body.Respiration monitoring device and magnetic Resonant device and timer are connected, and are used for monitoring patient respiration, trigger magnetic resonance elastography sequence mutually in fixing respiratory period Row radio-frequency pulse, when making to excite, abdominal part is in the state of geo-stationary every time, reaches to suppress the purpose of respiration artefacts.
Further, described mechanical wave generating means is antimagnetic material.
Further, described mechanical wave generating means is titanium alloy material.
Further, described respiration monitoring device is antimagnetic material.
Further, described respiration monitoring device is plastic material.
The present invention provides technical scheme to provide the benefit that:
Respiration monitoring device is used for monitoring person under inspection and breathes, and triggers magnetic resonance pulse signal, magnetic mutually in fixing respiratory period After resonant impulse signal sends, mechanical wave stimulation instrument produces shearing wave and acts on experimenter's liver, then is remembered by signal processing unit Record and calculate particle displacement situation, then calculate and space orientation through graphics processing unit, generate liver magnetic resonance elastic graph, MR imaging apparatus and mechanical wave stimulation instrument and the synchronizing information of respiration monitoring device is carried out by timer during whole.Its Middle mechanical wave generating means material is antimagnetic material, such as titanium alloy, it is impossible to affect magnetic field homogeneity.Wherein respiration monitoring device material Material is antimagnetic material, such as plastics, it is impossible to affect magnetic field homogeneity.Passed by cable between control panel and mechanical wave generating means Defeated signal, cable must pass through between waveguide turnover magnet, in order to avoid interference magnetic resonance signal.The present invention can generate patient's liver Resonance elastic diagram, the diagnosis to hepatic disease has great importance.
Accompanying drawing explanation
Fig. 1 is liver magnetic resonance elastogram apparatus structure schematic diagram
Fig. 2 is bellyband and the mechanical wave generating means being fixed thereon and respiration monitoring device
Detailed description of the invention
See accompanying drawing 1, the invention provides a kind of liver magnetic resonance elastogram device, including mechanical wave stimulation instrument, exhale Inhaling monitoring device, magnetic resonance equipment and timer, described magnetic resonance equipment includes information process unit, graphics processing unit and shows Showing that device, wherein said mechanical wave stimulation instrument are connected with signal processing unit, described graphics processing unit is for by signal processing The data that unit transmits carry out calculating and space orientation generate the spatial distribution map of coefficient of elasticity by inspection organization internal, Described display shows over the display for the view data that transmitted by graphics processing unit, described timer respectively with Mechanical wave stimulation instrument, respiration monitoring device, signal processing unit, graphics processing unit are connected with display, for synchrodrive Tool ripple stimulation instrument and magnetic resonance equipment so that mechanical wave stimulation instrument, respiration monitoring device, signal processing unit, image procossing list The time-sharing works such as unit, synchronizing information.Described mechanical wave stimulation instrument still further comprises control panel and mechanical wave generating means, its Middle control panel is positioned at equipment room, is used for regulating mechanical wave frequency and intensity, and mechanical wave generating means is fixed on bellyband, machinery Ripple acts on human liver surface, transmits mechanical wave to human body, and respiration monitoring device is also fixed on bellyband, is subject to for monitoring Inspection person breathes, and triggers magnetic resonance imaging mutually in fixing respiratory period, suppresses respiration artefacts.
Seeing accompanying drawing 2, mechanical wave generating means material is antimagnetic material, such as titanium alloy, it is impossible to affect magnetic field homogeneity.Its Middle respiration monitoring device material is also antimagnetic material, such as plastics, it is impossible to affect magnetic field homogeneity.Control panel and mechanical wave occur By cable transmission signal between device, cable must pass through between waveguide turnover magnet, in order to avoid interference magnetic resonance signal.Machinery After ripple acts on human body, produce shearing wave in tissue and particle displacement occurs, during this, application signal processing unit note Record the direction of each particle movement and and calculate particle displacement size.Graphics processing unit is for being transmitted across signal processing unit The data come carry out calculating and space orientation generate the spatial distribution map by the coefficient of elasticity examining organization internal.
The above, only the preferred embodiment of the present invention, but protection scope of the present invention is not limited thereto, ability Field technique personnel are it should be understood that without departing from the principle of the present invention and the spirit being limited its scope by claim and equivalent thereof In the case of, these embodiments can be modified and perfect, these are revised and improve also should be in protection scope of the present invention In.

Claims (5)

1. a binder type liver magnetic resonance elastogram device, it is characterised in that including:
Mechanical wave stimulation instrument, respiration monitoring device, magnetic resonance equipment and timer, described magnetic resonance equipment includes signal processing list Unit, graphics processing unit and display, wherein said mechanical wave stimulation instrument is connected with signal processing unit, described image procossing Unit carries out calculating for the data that transmitted by signal processing unit and space orientation generating by the bullet examining organization internal The spatial distribution map of property coefficient, described display shows at display for the view data transmitted by graphics processing unit On, described timer respectively with mechanical wave stimulation instrument, respiration monitoring device, signal processing unit, graphics processing unit and display Device is connected, for synchronization mechanism ripple stimulation instrument and magnetic resonance equipment so that mechanical wave stimulation instrument, signal processing unit, image The time-sharing works such as processing unit, synchronizing information, described mechanical wave stimulation instrument still further comprises control panel and mechanical wave occurs Device, wherein control panel is positioned at equipment room, is used for regulating mechanical wave frequency and intensity, and mechanical wave generating means fixes bellyband On, act on human liver surface, by mechanical wave transmission to human body, respiration monitoring device is for monitoring during elastogram Breathe, at fixing respiratory period phase acquisition signal, suppress respiration artefacts.
2. a kind of binder type liver magnetic resonance elastogram device as claimed in claim 1, it is characterised in that described mechanical wave Generating means is antimagnetic material.
3. a kind of binder type liver magnetic resonance elastogram device as claimed in claim 2, it is characterised in that described mechanical wave Generating means is titanium alloy material.
4. a kind of binder type liver magnetic resonance elastogram device as described in claim 1-3, it is characterised in that described breathing Monitoring device is antimagnetic material.
5. a kind of binder type liver magnetic resonance elastogram device as described in claim 1-4, it is characterised in that described breathing Monitoring device is plastic material.
CN201610525294.9A 2016-07-06 2016-07-06 A kind of binder type liver magnetic resonance elastogram device Pending CN106073782A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610525294.9A CN106073782A (en) 2016-07-06 2016-07-06 A kind of binder type liver magnetic resonance elastogram device

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Application Number Priority Date Filing Date Title
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Publications (1)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100049029A1 (en) * 2008-08-20 2010-02-25 Hong Kong Applied Science And Technology Research Institute Co., Ltd. Piezoelectric magnetic resonance elastograph (mre) driver system
CN101708123A (en) * 2009-10-28 2010-05-19 上海理工大学 Magnetic resonance elastography detection system of liver fibrosis classification research and method thereof
CN102871660A (en) * 2012-10-12 2013-01-16 上海卡勒幅磁共振技术有限公司 Method for restraining shadow of magnetic resonance imaging respiratory movement
CN103006217A (en) * 2012-12-21 2013-04-03 中国科学院深圳先进技术研究院 Cardiac magnetic resonance real-time film imaging method and system
CN103126675A (en) * 2011-11-25 2013-06-05 株式会社东芝 Magnetic resonance imaging apparatus
CN105078460A (en) * 2015-08-31 2015-11-25 郑州大学第一附属医院 Mammary gland magnetic resonance elasticity imaging apparatus
CN204909455U (en) * 2015-08-31 2015-12-30 郑州大学第一附属医院 Mammary gland magnetic resonance elasticity image device

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100049029A1 (en) * 2008-08-20 2010-02-25 Hong Kong Applied Science And Technology Research Institute Co., Ltd. Piezoelectric magnetic resonance elastograph (mre) driver system
CN101708123A (en) * 2009-10-28 2010-05-19 上海理工大学 Magnetic resonance elastography detection system of liver fibrosis classification research and method thereof
CN103126675A (en) * 2011-11-25 2013-06-05 株式会社东芝 Magnetic resonance imaging apparatus
CN102871660A (en) * 2012-10-12 2013-01-16 上海卡勒幅磁共振技术有限公司 Method for restraining shadow of magnetic resonance imaging respiratory movement
CN103006217A (en) * 2012-12-21 2013-04-03 中国科学院深圳先进技术研究院 Cardiac magnetic resonance real-time film imaging method and system
CN105078460A (en) * 2015-08-31 2015-11-25 郑州大学第一附属医院 Mammary gland magnetic resonance elasticity imaging apparatus
CN204909455U (en) * 2015-08-31 2015-12-30 郑州大学第一附属医院 Mammary gland magnetic resonance elasticity image device

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Application publication date: 20161109