CN106036831A - Food composition suitable for patients with chronic kidney diseases to eat and preparation method thereof - Google Patents
Food composition suitable for patients with chronic kidney diseases to eat and preparation method thereof Download PDFInfo
- Publication number
- CN106036831A CN106036831A CN201610362736.2A CN201610362736A CN106036831A CN 106036831 A CN106036831 A CN 106036831A CN 201610362736 A CN201610362736 A CN 201610362736A CN 106036831 A CN106036831 A CN 106036831A
- Authority
- CN
- China
- Prior art keywords
- semen
- parts
- fructus
- powder
- food composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 76
- 235000013305 food Nutrition 0.000 title claims abstract description 58
- 208000020832 chronic kidney disease Diseases 0.000 title claims abstract description 44
- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- 239000000843 powder Substances 0.000 claims abstract description 104
- 229920002472 Starch Polymers 0.000 claims abstract description 42
- 229920002774 Maltodextrin Polymers 0.000 claims abstract description 26
- 239000005913 Maltodextrin Substances 0.000 claims abstract description 26
- 229940035034 maltodextrin Drugs 0.000 claims abstract description 26
- 229920002261 Corn starch Polymers 0.000 claims abstract description 21
- 235000006487 Euryale ferox Nutrition 0.000 claims abstract description 21
- 244000268590 Euryale ferox Species 0.000 claims abstract description 21
- 240000000599 Lentinula edodes Species 0.000 claims abstract description 21
- 239000008120 corn starch Substances 0.000 claims abstract description 21
- 235000008390 olive oil Nutrition 0.000 claims abstract description 21
- 239000004006 olive oil Substances 0.000 claims abstract description 21
- 235000019698 starch Nutrition 0.000 claims abstract description 21
- 239000008107 starch Substances 0.000 claims abstract description 21
- 229940116298 l- malic acid Drugs 0.000 claims abstract description 20
- 235000007688 Lycopersicon esculentum Nutrition 0.000 claims abstract description 19
- 240000003768 Solanum lycopersicum Species 0.000 claims abstract description 19
- VSGNNIFQASZAOI-UHFFFAOYSA-L calcium acetate Chemical compound [Ca+2].CC([O-])=O.CC([O-])=O VSGNNIFQASZAOI-UHFFFAOYSA-L 0.000 claims abstract description 19
- 239000001639 calcium acetate Substances 0.000 claims abstract description 19
- 229960005147 calcium acetate Drugs 0.000 claims abstract description 19
- 235000011092 calcium acetate Nutrition 0.000 claims abstract description 19
- 235000016709 nutrition Nutrition 0.000 claims abstract description 18
- 230000035764 nutrition Effects 0.000 claims abstract description 18
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims abstract 2
- 240000002853 Nelumbo nucifera Species 0.000 claims abstract 2
- 210000000582 semen Anatomy 0.000 claims description 207
- 239000002994 raw material Substances 0.000 claims description 41
- 239000003921 oil Substances 0.000 claims description 26
- 235000019198 oils Nutrition 0.000 claims description 26
- 240000003183 Manihot esculenta Species 0.000 claims description 21
- 235000016735 Manihot esculenta subsp esculenta Nutrition 0.000 claims description 21
- 235000013312 flour Nutrition 0.000 claims description 21
- 235000019890 Amylum Nutrition 0.000 claims description 20
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 20
- 235000001715 Lentinula edodes Nutrition 0.000 claims description 20
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims description 20
- 235000009392 Vitis Nutrition 0.000 claims description 20
- 241000219095 Vitis Species 0.000 claims description 20
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims description 20
- 238000001035 drying Methods 0.000 claims description 19
- 235000012054 meals Nutrition 0.000 claims description 19
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 claims description 18
- 238000005469 granulation Methods 0.000 claims description 18
- 230000003179 granulation Effects 0.000 claims description 18
- 239000008187 granular material Substances 0.000 claims description 14
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 claims description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- 238000002156 mixing Methods 0.000 claims description 13
- 235000011194 food seasoning agent Nutrition 0.000 claims description 12
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims description 10
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims description 10
- 229930003268 Vitamin C Natural products 0.000 claims description 10
- 235000019152 folic acid Nutrition 0.000 claims description 10
- 239000011724 folic acid Substances 0.000 claims description 10
- 229960000304 folic acid Drugs 0.000 claims description 10
- 239000000463 material Substances 0.000 claims description 10
- 235000001968 nicotinic acid Nutrition 0.000 claims description 10
- 239000011664 nicotinic acid Substances 0.000 claims description 10
- 229960003512 nicotinic acid Drugs 0.000 claims description 10
- 235000002378 plant sterols Nutrition 0.000 claims description 10
- 150000008442 polyphenolic compounds Chemical class 0.000 claims description 10
- 235000013824 polyphenols Nutrition 0.000 claims description 10
- 235000019154 vitamin C Nutrition 0.000 claims description 10
- 239000011718 vitamin C Substances 0.000 claims description 10
- 244000269722 Thea sinensis Species 0.000 claims description 9
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 claims description 9
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 claims description 9
- 229920001661 Chitosan Polymers 0.000 claims description 8
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 claims description 8
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims description 8
- 229930003471 Vitamin B2 Natural products 0.000 claims description 8
- 229960002477 riboflavin Drugs 0.000 claims description 8
- 238000007873 sieving Methods 0.000 claims description 8
- 239000011716 vitamin B2 Substances 0.000 claims description 8
- 235000019164 vitamin B2 Nutrition 0.000 claims description 8
- 229930003451 Vitamin B1 Natural products 0.000 claims description 7
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 claims description 7
- 229960003495 thiamine Drugs 0.000 claims description 7
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 claims description 7
- 235000010374 vitamin B1 Nutrition 0.000 claims description 7
- 239000011691 vitamin B1 Substances 0.000 claims description 7
- 239000011726 vitamin B6 Substances 0.000 claims description 7
- 235000019158 vitamin B6 Nutrition 0.000 claims description 7
- 229940011671 vitamin b6 Drugs 0.000 claims description 7
- 238000005520 cutting process Methods 0.000 claims description 6
- 238000003756 stirring Methods 0.000 claims description 6
- 229930003270 Vitamin B Natural products 0.000 claims description 5
- 238000012545 processing Methods 0.000 claims description 5
- 235000019156 vitamin B Nutrition 0.000 claims description 5
- 239000011720 vitamin B Substances 0.000 claims description 5
- 238000005303 weighing Methods 0.000 claims description 3
- 229920001353 Dextrin Polymers 0.000 claims 1
- 239000004375 Dextrin Substances 0.000 claims 1
- 235000019425 dextrin Nutrition 0.000 claims 1
- 239000013049 sediment Substances 0.000 claims 1
- 239000002023 wood Substances 0.000 claims 1
- 241000282414 Homo sapiens Species 0.000 abstract description 10
- 230000006870 function Effects 0.000 abstract description 4
- 210000004185 liver Anatomy 0.000 abstract description 4
- 210000000952 spleen Anatomy 0.000 abstract description 4
- 210000002784 stomach Anatomy 0.000 abstract description 4
- 235000021307 Triticum Nutrition 0.000 abstract description 3
- 210000000056 organ Anatomy 0.000 abstract description 2
- 230000001105 regulatory effect Effects 0.000 abstract description 2
- 235000013399 edible fruits Nutrition 0.000 abstract 3
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 abstract 2
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 abstract 1
- 244000247812 Amorphophallus rivieri Species 0.000 abstract 1
- 235000001206 Amorphophallus rivieri Nutrition 0.000 abstract 1
- 235000014036 Castanea Nutrition 0.000 abstract 1
- 241001070941 Castanea Species 0.000 abstract 1
- 244000077995 Coix lacryma jobi Species 0.000 abstract 1
- 235000009917 Crataegus X brevipes Nutrition 0.000 abstract 1
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 abstract 1
- 235000009685 Crataegus X maligna Nutrition 0.000 abstract 1
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 abstract 1
- 235000009486 Crataegus bullatus Nutrition 0.000 abstract 1
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 abstract 1
- 235000009682 Crataegus limnophila Nutrition 0.000 abstract 1
- 240000000171 Crataegus monogyna Species 0.000 abstract 1
- 235000004423 Crataegus monogyna Nutrition 0.000 abstract 1
- 235000002313 Crataegus paludosa Nutrition 0.000 abstract 1
- 235000009840 Crataegus x incaedua Nutrition 0.000 abstract 1
- 241000371652 Curvularia clavata Species 0.000 abstract 1
- 244000000626 Daucus carota Species 0.000 abstract 1
- 235000002767 Daucus carota Nutrition 0.000 abstract 1
- 235000010469 Glycine max Nutrition 0.000 abstract 1
- 244000068988 Glycine max Species 0.000 abstract 1
- 244000017020 Ipomoea batatas Species 0.000 abstract 1
- 235000002678 Ipomoea batatas Nutrition 0.000 abstract 1
- 240000007049 Juglans regia Species 0.000 abstract 1
- 235000009496 Juglans regia Nutrition 0.000 abstract 1
- 229920002752 Konjac Polymers 0.000 abstract 1
- 235000015468 Lycium chinense Nutrition 0.000 abstract 1
- 244000241872 Lycium chinense Species 0.000 abstract 1
- 235000008708 Morus alba Nutrition 0.000 abstract 1
- 240000000249 Morus alba Species 0.000 abstract 1
- 244000124853 Perilla frutescens Species 0.000 abstract 1
- 235000004348 Perilla frutescens Nutrition 0.000 abstract 1
- 235000006089 Phaseolus angularis Nutrition 0.000 abstract 1
- 235000010575 Pueraria lobata Nutrition 0.000 abstract 1
- 244000046146 Pueraria lobata Species 0.000 abstract 1
- 244000062793 Sorghum vulgare Species 0.000 abstract 1
- 244000098338 Triticum aestivum Species 0.000 abstract 1
- 235000010711 Vigna angularis Nutrition 0.000 abstract 1
- 240000007098 Vigna angularis Species 0.000 abstract 1
- 235000014787 Vitis vinifera Nutrition 0.000 abstract 1
- 240000006365 Vitis vinifera Species 0.000 abstract 1
- 108010046377 Whey Proteins Proteins 0.000 abstract 1
- 102000007544 Whey Proteins Human genes 0.000 abstract 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 abstract 1
- 244000052616 bacterial pathogen Species 0.000 abstract 1
- 235000007215 black sesame Nutrition 0.000 abstract 1
- 235000005687 corn oil Nutrition 0.000 abstract 1
- 239000002285 corn oil Substances 0.000 abstract 1
- 235000020930 dietary requirements Nutrition 0.000 abstract 1
- 235000004879 dioscorea Nutrition 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 239000000252 konjac Substances 0.000 abstract 1
- 235000010485 konjac Nutrition 0.000 abstract 1
- 235000011090 malic acid Nutrition 0.000 abstract 1
- 235000019713 millet Nutrition 0.000 abstract 1
- 229920001592 potato starch Polymers 0.000 abstract 1
- 235000020234 walnut Nutrition 0.000 abstract 1
- 229940100445 wheat starch Drugs 0.000 abstract 1
- 235000021119 whey protein Nutrition 0.000 abstract 1
- 235000018102 proteins Nutrition 0.000 description 49
- 102000004169 proteins and genes Human genes 0.000 description 49
- 108090000623 proteins and genes Proteins 0.000 description 49
- 210000002700 urine Anatomy 0.000 description 39
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 34
- 208000017169 kidney disease Diseases 0.000 description 32
- 210000004369 blood Anatomy 0.000 description 30
- 239000008280 blood Substances 0.000 description 30
- 230000001684 chronic effect Effects 0.000 description 23
- 235000005911 diet Nutrition 0.000 description 18
- 229940109239 creatinine Drugs 0.000 description 17
- 210000002966 serum Anatomy 0.000 description 17
- PNNCWTXUWKENPE-UHFFFAOYSA-N [N].NC(N)=O Chemical compound [N].NC(N)=O PNNCWTXUWKENPE-UHFFFAOYSA-N 0.000 description 16
- 230000037213 diet Effects 0.000 description 16
- 230000000694 effects Effects 0.000 description 16
- 238000009472 formulation Methods 0.000 description 15
- 208000007342 Diabetic Nephropathies Diseases 0.000 description 13
- 208000033679 diabetic kidney disease Diseases 0.000 description 13
- 208000024891 symptom Diseases 0.000 description 11
- 239000003814 drug Substances 0.000 description 10
- 210000003734 kidney Anatomy 0.000 description 10
- 238000000034 method Methods 0.000 description 10
- ZSJLQEPLLKMAKR-GKHCUFPYSA-N streptozocin Chemical compound O=NN(C)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O ZSJLQEPLLKMAKR-GKHCUFPYSA-N 0.000 description 10
- ZSJLQEPLLKMAKR-UHFFFAOYSA-N Streptozotocin Natural products O=NN(C)C(=O)NC1C(O)OC(CO)C(O)C1O ZSJLQEPLLKMAKR-UHFFFAOYSA-N 0.000 description 9
- 230000002265 prevention Effects 0.000 description 9
- 229960001052 streptozocin Drugs 0.000 description 9
- 235000021152 breakfast Nutrition 0.000 description 8
- 230000003203 everyday effect Effects 0.000 description 8
- 238000009533 lab test Methods 0.000 description 8
- 239000000126 substance Substances 0.000 description 8
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 7
- 235000021590 normal diet Nutrition 0.000 description 7
- 241000700159 Rattus Species 0.000 description 6
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 6
- 239000003153 chemical reaction reagent Substances 0.000 description 5
- 201000010099 disease Diseases 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 5
- 230000003907 kidney function Effects 0.000 description 5
- 241001465754 Metazoa Species 0.000 description 4
- 230000037396 body weight Effects 0.000 description 4
- FAKRSMQSSFJEIM-RQJHMYQMSA-N captopril Chemical compound SC[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O FAKRSMQSSFJEIM-RQJHMYQMSA-N 0.000 description 4
- 230000008859 change Effects 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 4
- 210000000585 glomerular basement membrane Anatomy 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 239000004202 carbamide Substances 0.000 description 3
- 235000013877 carbamide Nutrition 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 239000008103 glucose Substances 0.000 description 3
- 235000020660 omega-3 fatty acid Nutrition 0.000 description 3
- 238000012764 semi-quantitative analysis Methods 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 235000015112 vegetable and seed oil Nutrition 0.000 description 3
- 206010001580 Albuminuria Diseases 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 208000037157 Azotemia Diseases 0.000 description 2
- AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 description 2
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 2
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 2
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- -1 L MALIC ACID Substances 0.000 description 2
- 208000002720 Malnutrition Diseases 0.000 description 2
- 241000699666 Mus <mouse, genus> Species 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 2
- 206010029164 Nephrotic syndrome Diseases 0.000 description 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 2
- 241000209140 Triticum Species 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000003513 alkali Substances 0.000 description 2
- 238000010171 animal model Methods 0.000 description 2
- 239000007979 citrate buffer Substances 0.000 description 2
- 206010012601 diabetes mellitus Diseases 0.000 description 2
- 230000000378 dietary effect Effects 0.000 description 2
- 238000004043 dyeing Methods 0.000 description 2
- 210000002744 extracellular matrix Anatomy 0.000 description 2
- 235000019197 fats Nutrition 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 235000000824 malnutrition Nutrition 0.000 description 2
- 230000001071 malnutrition Effects 0.000 description 2
- 235000021281 monounsaturated fatty acids Nutrition 0.000 description 2
- 201000008383 nephritis Diseases 0.000 description 2
- 208000015380 nutritional deficiency disease Diseases 0.000 description 2
- 230000036285 pathological change Effects 0.000 description 2
- 231100000915 pathological change Toxicity 0.000 description 2
- 230000001575 pathological effect Effects 0.000 description 2
- 230000002085 persistent effect Effects 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 239000011591 potassium Substances 0.000 description 2
- 229910052700 potassium Inorganic materials 0.000 description 2
- 238000004393 prognosis Methods 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 230000001629 suppression Effects 0.000 description 2
- 210000001835 viscera Anatomy 0.000 description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 1
- 208000010444 Acidosis Diseases 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 240000004307 Citrus medica Species 0.000 description 1
- 208000026372 Congenital cystic kidney disease Diseases 0.000 description 1
- 206010018364 Glomerulonephritis Diseases 0.000 description 1
- 206010018372 Glomerulonephritis membranous Diseases 0.000 description 1
- 229920002527 Glycogen Polymers 0.000 description 1
- 201000005569 Gout Diseases 0.000 description 1
- 206010069440 Henoch-Schonlein purpura nephritis Diseases 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 101000777301 Homo sapiens Uteroglobin Proteins 0.000 description 1
- 206010055171 Hypertensive nephropathy Diseases 0.000 description 1
- 208000010159 IgA glomerulonephritis Diseases 0.000 description 1
- 206010021263 IgA nephropathy Diseases 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 244000046052 Phaseolus vulgaris Species 0.000 description 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 241000219780 Pueraria Species 0.000 description 1
- 206010037596 Pyelonephritis Diseases 0.000 description 1
- 241000700157 Rattus norvegicus Species 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- 206010038468 Renal hypertrophy Diseases 0.000 description 1
- 206010061481 Renal injury Diseases 0.000 description 1
- 102100031083 Uteroglobin Human genes 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 229960000583 acetic acid Drugs 0.000 description 1
- HFNUUHLSQPLBQI-UHFFFAOYSA-N acetic acid;calcium Chemical compound [Ca].CC(O)=O HFNUUHLSQPLBQI-UHFFFAOYSA-N 0.000 description 1
- 230000007950 acidosis Effects 0.000 description 1
- 208000026545 acidosis disease Diseases 0.000 description 1
- 229940009456 adriamycin Drugs 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 229960000830 captopril Drugs 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- CYQFCXCEBYINGO-IAGOWNOFSA-N delta1-THC Chemical compound C1=C(C)CC[C@H]2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3[C@@H]21 CYQFCXCEBYINGO-IAGOWNOFSA-N 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 235000019007 dietary guidelines Nutrition 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 230000008451 emotion Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 210000001105 femoral artery Anatomy 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 210000001707 glomerular endothelial cell Anatomy 0.000 description 1
- 210000002601 glomerular mesangium Anatomy 0.000 description 1
- 206010061989 glomerulosclerosis Diseases 0.000 description 1
- 229940096919 glycogen Drugs 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 239000007928 intraperitoneal injection Substances 0.000 description 1
- 210000003292 kidney cell Anatomy 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 201000008627 kidney hypertrophy Diseases 0.000 description 1
- 208000037806 kidney injury Diseases 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 235000020905 low-protein-diet Nutrition 0.000 description 1
- 206010025135 lupus erythematosus Diseases 0.000 description 1
- 201000008350 membranous glomerulonephritis Diseases 0.000 description 1
- 231100000855 membranous nephropathy Toxicity 0.000 description 1
- 210000000713 mesentery Anatomy 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 238000011617 nephropathy animal model Methods 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 239000002417 nutraceutical Substances 0.000 description 1
- 235000021436 nutraceutical agent Nutrition 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 235000003715 nutritional status Nutrition 0.000 description 1
- 235000008935 nutritious Nutrition 0.000 description 1
- 229940012843 omega-3 fatty acid Drugs 0.000 description 1
- 230000001662 opsonic effect Effects 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 208000030761 polycystic kidney disease Diseases 0.000 description 1
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 230000022558 protein metabolic process Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 229940100486 rice starch Drugs 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 208000009852 uremia Diseases 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a food composition suitable for patients with chronic kidney diseases to eat. The invention is characterized in that the food composition suitable for the patients with the chronic kidney diseases to eat is prepared from the following ingredients in parts by weight: lotus root starch, sweet potato flour, wheat starch, corn starch, millets, black rice, coix seeds, adzuki beans, Chinese yams, euryale ferox seeds, konjac, chestnut kernels, black sesame seeds, fermented black soybeans, shiitake mushrooms, mulberry fruits, walnut kernels, Chinese wolfberry fruits, red dates, raisins, wheat germs, kudzu-vine root powder, hawthorn fruit powder, tomato powder, carrot powder, concentrated whey protein, olive oil, perilla frutescens oil, corn oil, maltodextrin, L-carnitine, L-malic acid and calcium acetate. The invention further discloses a preparation method of the food composition suitable for the patients with the chronic kidney diseases to eat. The food composition provided by the invention is balanced in nutrition, and is suitable for dietary requirements of the patients with the chronic kidney diseases; moreover, the food composition also has the functions of regulating the important human organs, including the liver, the spleen, the stomach and so on.
Description
Technical field
The application belongs to nutraceutical field, specifically, relates to the diet group that a kind of applicable Patients with Chronic Renal Disease is taken
Compound and preparation method thereof.
Background technology
Nephropathy, between viscera, all remains dynamic equilibrium between interior environment and external environment.The interior external world multiple pathogenic because of
If element destroys the balance of human body, cause internal organs QI and blood functional disorder, sick and in kidney, then cause the generation of kidney disease.Send out
Sick prerequisite, is the power of human righteousness, and evil orthogonal strives and the situation of both sides' prosperity and decline.Cause the disease of kidney disease
Because of varied, as the multiple internal and external factors such as six climate exopathogens, seven emotions, diet, work and rest, exhaustion due to sexual indulgence, poison of drug, unexpected injury all can cause a disease.And
And, often interact at generation, the evolution process of disease, the cause of disease and its pathological product, reciprocal causation.
In clinic, it is diagnosed as glomerulonephritis, latent nephritis, pyelonephritis, Henoch Schonlein purpura nephritis, lupus erythematosus kidney
Inflammation, gout kidney, iga nephropathy, nephrotic syndrome, membranous nephropathy, nephrotic syndrome, diabetic nephropathy, hypertensive nephropathy, polycystic kidney
Etc., when the morbidity of these nephropathy delays difficulty more, the time, patient urine and relevant physiochemical indice occurred different more than three months
Often, Renal Paphology, iconography note abnormalities, and all can be collectively referred to as " chronic nephropathy ".Chronic nephropathy such as fails timely and effective treatment,
The progress that causes that sb.'s illness took a turn for the worse, then delay with the course of disease, and Patients with Chronic Renal Disease will develop into chronic renal insufficiency, renal failure,
End form becomes uremia.
Nutrition treatment is one of chronic nephropathy essential therapeutic arsenals, its object is to improve malnutrition, delay renal function
Deteriorate process, specifically, be on the basis of reaching and maintaining rational nutriture, reduce blood urea nitrogen delay,
Alleviate glomerule height to filter and glomerular sclerosis, alleviate glomerular basement membrane and mesentery infringement, correct water and rock-soil coupling and acid
Alkali is unbalance, reduces and delay generation and the development of complication.Finding according to up-to-date scientific research, the kidney of the mankind has the strongest
Self-repairing capability.After kidney injury, ripe kidney cell can be divided into the thin of oneself more initial condition in affected area
Born of the same parents, are divided into the cell type needed for repair of damaged tissues the most again.In order to well promote kidney reparation, slow in nutrition treatment
Property nephropathy limit protein diet while, should ensure that the energy and balanced in nutrition of abundance, usually can also eat black food, as black more
Semen Sesami, fructus zizaniae caduciflorae, Semen sojae atricolor, and Semen Juglandis, Semen Castaneae, Fructus Lycii etc..Because malnutrition directly affects the recovery of renal function, complication
Generation and prognosis.
The diet conservancy of science is the important measures for the treatment of chronic nephropathy, and diet care has act in the preventing and treating of nephropathy
The curative effect of the effect of foot weight, even direct relation nephropathy and prognosis.Because can be alleviated with relief of symptoms by science diet
Damage, improves patients ' life quality.Particularly cut down one's diet middle protein content, can improve azotemia, alleviate albuminuria pair
The damage of kidney, also helps reduction serium inorganic phosphorus and alleviates acidosis.Treated by limit protein diet thus reach: 1. prevent and entangle
The positive relevant symptom of chronic kidney disease, sign and complication.2. patient can be kept good correction protein metabolism is abnormal while
Nutritional status and lean body mass quality.3. protect residual renal function, delay patient to enter the purpose of dialysis time.
Existing nutrition treatment chronic nephropathy exists that kind is single, mouthfeel is single, just for the diet limiting low albumen
Scheme, to the protection of residual renal function with take good care of obvious deficiency, and cannot to other vitals of human body such as liver, spleen,
Stomaches etc. are nursed one's health.
Summary of the invention
In view of this, the application is for above-mentioned problem, it is provided that the diet group that a kind of applicable Patients with Chronic Renal Disease is taken
Compound, while Restrict protein diet is provided, it is ensured that the content of high-quality protein accounts between the 50-70% of total protein,
And ensure balanced in nutrition.The food composition balanced in nutrition of this invention provides the diet of a kind of applicable Patients with Chronic Renal Disease
Requirement, the most also has the body weight for humans such as conditioning liver, spleen, stomach and wants the effects such as organ.
In order to solve above-mentioned technical problem, this application discloses the combinations of foods that a kind of applicable Patients with Chronic Renal Disease is taken
Thing, includes following components according to weight portion: Amylum Nelumbinis Rhizomatis 100-250 part, tapioca flour 100-250 part, and wheaten starch 100-250 part is beautiful
Rice starch 100-250 part, Semen setariae 20-50 part, fructus zizaniae caduciflorae 20-50 part, Semen Coicis 10-40 part, Semen Phaseoli 20-50 part, Rhizoma Dioscoreae 20-50
Part, Semen Euryales 20-50 part, Rhizoma amorphophalli 50-65 part, Semen Castaneae 20-50 part, Semen Sesami Nigrum 20-30 part, Semen sojae atricolor Semen Sojae Preparatum 20-40 part, Lentinus Edodes 5-10
Part, Fructus Mori 10-20 part, Semen Juglandis 20-40 part, Fructus Lycii 20-30 part, Fructus Jujubae 15-30 part, dried Fructus Vitis viniferae 10-30 part, wheat-germ meal 20-
50 parts, powder of Radix Puerariae 20-50 part, Fructus Crataegi powder 10-30 part, tomato powder 10-40 part, Radix Dauci Sativae powder 10-20 part, concentrated lactoalbumin
84.5-98.5 part, olive oil 73-80 part, Oleum Perillae 9.5-13 part, Semen Maydis oil 50-55 part, maltodextrin 63-85 part, L-meat
Alkali 15-25 part, L MALIC ACID 8.5-29.5 part, calcium acetate 9-11 part.
Further, in terms of the weight total amount of above-mentioned each component, this applicable Patients with Chronic Renal Disease and food balanced in nutrition
Compositions also includes following components: 4g/kg plant sterol, 2.2g/kg oligomeric xylose, 0.9g/kg oligo-chitosan, 0.2g/kg
Tea polyphenols, the vitamin C of 150mg/kg, the vitamin B1 of 1.5mg/kg, the vitamin B2 of 2mg/kg, the vitamin of 3mg/kg
The nicotinic acid of B6,20mg/kg, the folic acid of 0.8mg/kg.
Further, this food composition includes following components according to weight portion: Amylum Nelumbinis Rhizomatis 100-250 part, tapioca flour 100-
250 parts, wheaten starch 100-250 part, corn starch 100-250 part, Semen setariae 20-50 part, fructus zizaniae caduciflorae 20-50 part, Semen Coicis 10-40
Part, Semen Phaseoli 20-50 part, Rhizoma Dioscoreae 20-50 part, Semen Euryales 20-50 part, Rhizoma amorphophalli 50-65 part, Semen Castaneae 20-50 part, Semen Sesami Nigrum 20-30
Part, Semen sojae atricolor Semen Sojae Preparatum 20-40 part, Lentinus Edodes 5-10 part, Fructus Mori 10-20 part, Semen Juglandis 20-40 part, Fructus Lycii 20-30 part, Fructus Jujubae 15-30
Part, dried Fructus Vitis viniferae 10-30 part, wheat-germ meal 20-50 part, powder of Radix Puerariae 20-50 part, Fructus Crataegi powder 10-30 part, tomato powder 10-40 part,
Radix Dauci Sativae powder 10-20 part, concentrated lactoalbumin 84.5-98.5 part, olive oil 73-80 part, Oleum Perillae 9.5-13 part, Semen Maydis oil
50-55 part, maltodextrin 63-85 part, VBT 15-25 part, L MALIC ACID 8.5-29.5 part, calcium acetate 9-11 part.
The application also provides for the preparation method of the food composition that a kind of applicable Patients with Chronic Renal Disease is taken, including following step
Rapid:
1) weigh: according to mass parts weighing following components:
Amylum Nelumbinis Rhizomatis 100-250 part, tapioca flour 100-250 part, wheaten starch 100-250 part, corn starch 100-250 part, little
Rice 20-50 part, fructus zizaniae caduciflorae 20-50 part, Semen Coicis 10-40 part, Semen Phaseoli 20-50 part, Rhizoma Dioscoreae 20-50 part, Semen Euryales 20-50 part, Rhizoma amorphophalli
50-65 part, Semen Castaneae 20-50 part, Semen Sesami Nigrum 20-30 part, Semen sojae atricolor Semen Sojae Preparatum 20-40 part, Lentinus Edodes 5-10 part, Fructus Mori 10-20 part, Semen Juglandis
20-40 part, Fructus Lycii 20-30 part, Fructus Jujubae 15-30 part, dried Fructus Vitis viniferae 10-30 part, wheat-germ meal 20-50 part, powder of Radix Puerariae 20-50 part,
Fructus Crataegi powder 10-30 part, tomato powder 10-40 part, Radix Dauci Sativae powder 10-20 part, concentrated lactoalbumin 84.5-98.5 part, olive oil
73-80 part, Oleum Perillae 9.5-13 part, Semen Maydis oil 50-55 part, maltodextrin 63-85 part, VBT 15-25 part, L MALIC ACID
8.5-29.5 part, calcium acetate 9-11 part；
2) by load weighted Semen setariae, fructus zizaniae caduciflorae, Semen Coicis, Semen Phaseoli, Rhizoma Dioscoreae, Semen Euryales, Rhizoma amorphophalli, Semen Castaneae, Semen Sesami Nigrum, wash respectively
Only, cook, hot-air seasoning；Load weighted Lentinus Edodes cleaned, cook, hot-air seasoning, and irradiate with ultraviolet or expose in the sun
Shine one hour；Above-mentioned raw materials is all ground into fine powder；
3) by load weighted Semen sojae atricolor Semen Sojae Preparatum, Fructus Mori, Semen Juglandis, Fructus Lycii, Fructus Jujubae, dried Fructus Vitis viniferae, fine powder also it is ground into；
4) by load weighted maltodextrin 33.5-37 part olive oil, Oleum Perillae, Semen Maydis oil, it is spray-dried and makes powder
End；
5) by load weighted Amylum Nelumbinis Rhizomatis, tapioca flour, wheaten starch, corn starch, wheat-germ meal, powder of Radix Puerariae, Fructus Crataegi powder, western red
Fructus Kaki powder, Radix Dauci Sativae powder, concentrated lactoalbumin, maltodextrin 29.5-48 part, VBT, L MALIC ACID, calcium acetate；
6) by step 1)-step 5) weigh the various components that obtain and put into three-dimensional mixer mixing 10-20min；Mixing is all
Even rear standby；
7) by step 6) mixed material that obtains adds high speed wet granulator；Open High-Speed Automatic wet granulator, add
It is pressed in 0.65pa；Raw material is stirred by speed governing degree to 18r/min；The ratio adding 40-110ml pure water in 1kg raw material is accurate
Really measuring institute's water requirement, after mixing 2-3 minute, speed governing degree to 15-33r/min carries out granule cutting 15-33min；Afterwards followed by
Continuous stirring raw material 3-6 minute；Open outlet valve, collect granulation raw material, send drying workshop；It is added to substandard product to wait to pelletize former
Material is pelletized again；
8) drying and processing: by step 7) the granulation product that obtains puts into the drying baker that temperature is 40-46 DEG C dries
Process 2.5h；
9) granulate and sieving: pour the 30 mesh products dried into vibrations sieving machine, carry out granulate and sieve；It is qualified to collect
Product, prepares applicable Patients with Chronic Renal Disease and food composition balanced in nutrition.
Further, step 6) specifically according to following steps implement: by step 1)-step 5) obtain various components mixing
After Jun Yun, by step 1)-step 5) in terms of the total amount of various components that obtains, further add 4g/kg plant sterol, 2.2g/
Kg oligomeric xylose, 0.9g/kg oligo-chitosan, the tea polyphenols of 0.2g/kg, the vitamin C of 150mg/kg, the dimension life of 1.5mg/kg
Element B1, the vitamin B of 2mg/kg2, the vitamin B of 3mg/kg6, the nicotinic acid of 20mg/kg, the folic acid of 0.8mg/kg, mix homogeneously,
Standby.
The instructions of taking of the food composition that this applicable Patients with Chronic Renal Disease is taken, opens by the temperature of about 40 DEG C to 50 DEG C
Water carries out reconstituting can be taken, in order to avoid destroying active component therein.
Compared with prior art, the application can obtain and include techniques below effect:
1) protein in the applicable Patients with Chronic Renal Disease of the present invention and food composition balanced in nutrition, fat, carbon aquation
Compound, from multiple different food, meets the diversified requirement of diet, and the ratio between food is reasonable, accords with completely
Close the Patients with Chronic Renal Disease requirement to three nutritious elements (protein, fat, carbohydrate), the particularly need to protein
Asking, in protein, the ratio shared by high quality protein is reasonable, reaches more than the 50% of total protein, and rich in needed by human
Aminoacid；In fatty acid, monounsaturated fatty acid, polyunsaturated fatty acid meet " Chinese residents diet nutrient reference absorption
Amount " requirement, wherein (ω-3): (ω-6) ratio is reasonable.These food compositions the most edible have prevention and correct chronic
The relevant symptom of nephropathy, sign and complication effect, the most also have the liver protecting, the protection merit such as cardiovascular and cerebrovascular vessel, function of spleen and stomach regulating
Energy.
The content of the protein of the food composition of the present invention meets the dietetic requirement of chronic nephropathy, especially high-quality protein
The content of matter accounts for the content of gross protein and reaches between 50%-70%, protein to be guaranteed while ensureing low protein diet
Quality, thus ensure balanced in nutrition.Further contemplate simultaneously and increase containing of high omega-3 fatty acid and high monounsaturated fatty acid
Amount, and ensures (ω-3): the ratio of (ω-6) meets the requirement of World Health Organization (WHO), the most also to ensure low sodium, low-phosphorous and
The food feature of limit potassium.Such as, Amylum Nelumbinis Rhizomatis, tapioca flour, wheaten starch, corn starch are all the food containing extremely low protein, greatly
In corresponding span, the span of the raw materials such as Semen setariae, fructus zizaniae caduciflorae, Semen Phaseoli, Rhizoma Dioscoreae will be reduced accordingly, thus affect
Opsonic action to other vitals of human body；If less than corresponding span, then need to increase Semen setariae, fructus zizaniae caduciflorae, red little
The span of the raw material such as bean, Rhizoma Dioscoreae, causes ensureing the 50%-that high quality protein content reaches total protein content
70%, and affect Patients with Chronic Renal Disease to low sodium, the low-phosphorous and dietetic requirement of limit potassium, thus affect the clinical treatment of chronic nephropathy
Result.Above-mentioned food composition complies fully with diet substantially wanting Food Diversity in " Chinese residents dietary guidelines "
Ask, also assures that the absorption of other trace element, it is ensured that balanced in nutrition simultaneously.
Certainly, the arbitrary product implementing the application must be not necessarily required to reach all the above technique effect simultaneously.
Detailed description of the invention
Presently filed embodiment is described in detail, thereby to the application how application technology below in conjunction with embodiment
Means solve technical problem and reach the process that realizes of technology effect and can fully understand and implement according to this.
Embodiment 1
The food composition that a kind of applicable Patients with Chronic Renal Disease is taken, including the component of following weight portion:
Amylum Nelumbinis Rhizomatis 250 parts, tapioca flour 250 parts, wheaten starch 100 parts, corn starch 250 parts, Semen setariae 50 parts, fructus zizaniae caduciflorae 30 parts,
Semen Coicis 40 parts, Semen Phaseoli 40 parts, Rhizoma Dioscoreae 50 parts, Semen Euryales 30 parts, Rhizoma amorphophalli 55 parts, Semen Castaneae 50 parts, Semen Sesami Nigrum 25 parts, Semen sojae atricolor Semen Sojae Preparatum 30
Part, 10 parts of Lentinus Edodes, Fructus Mori 20 parts, Semen Juglandis 40 parts, Fructus Lycii 30 parts, Fructus Jujubae 25 parts, dried Fructus Vitis viniferae 15 parts, wheat-germ meal 40 parts, Radix Puerariae
20 parts of powder, Fructus Crataegi powder 30 parts, tomato powder 25 parts, Radix Dauci Sativae powder 10 parts, concentrated lactoalbumin 86 parts, 73 parts of olive oil, Fructus Perillae
Oil 10.4 parts, Semen Maydis oil 50 parts, maltodextrin 79 parts, VBT 25 parts, L MALIC ACID 20 parts, calcium acetate 9 parts.
The preparation method of the food composition that above-mentioned applicable Patients with Chronic Renal Disease is taken is as follows:
Each component is weighed according to above-mentioned consumption, by load weighted Semen setariae, fructus zizaniae caduciflorae, Semen Coicis, Semen Phaseoli, Rhizoma Dioscoreae, Semen Euryales,
Rhizoma amorphophalli, Semen Castaneae, Semen Sesami Nigrum, clean respectively, cook, hot-air seasoning；Load weighted Lentinus Edodes cleaned, cook, hot-air seasoning, and use
Ultraviolet irradiates or tans by the sun in the sun one hour；Above-mentioned raw materials is all ground into fine powder；By load weighted Semen sojae atricolor Semen Sojae Preparatum,
Fructus Mori, Semen Juglandis, Fructus Lycii, Fructus Jujubae, dried Fructus Vitis viniferae, also it is ground into fine powder；By load weighted maltodextrin 33.5 parts olive oil, Folium Perillae
Seed oil, Semen Maydis oil, it is spray-dried and makes powder；By load weighted Amylum Nelumbinis Rhizomatis, tapioca flour, wheaten starch, corn starch, wheat germ
Powder, powder of Radix Puerariae, Fructus Crataegi powder, tomato powder, Radix Dauci Sativae powder, concentrated lactoalbumin, maltodextrin 45.5 parts, VBT, L-Fructus Mali pumilae
Acid, calcium acetate；Various components are put into three-dimensional mixer mixing 10min；After mix homogeneously standby；Mixed material is added at a high speed
Wet granulator；Open High-Speed Automatic wet granulator, add and be pressed in 0.65pa；Raw material is stirred by speed governing degree to 18r/min；
The ratio adding 40ml pure water in 1kg raw material accurately measures the required water yield, and after mixing 2 minutes, speed governing degree to 15r/min is carried out
Granule cutting 33min；It is further continued for afterwards stirring raw material 3 minutes；Open outlet valve, collect granulation raw material, send drying workshop；Will not
Qualified products are added to treat that granulation raw material is pelletized again；Granulation product is put into the drying baker that temperature is 40 DEG C and carries out drying and processing
2.5h；Pour the 30 mesh products dried into vibrations sieving machine, carry out granulate and sieve；Collect qualified products, prepare suitable
Close Patients with Chronic Renal Disease and food composition balanced in nutrition.
Wheat, female, 53 years old, suffers from chronic nephropathy 7 years.Through chemical examination, urine protein is 3.6g/L (urine protein 3+), and serum creatinine is:
465umol/L, blood urea nitrogen is 15.1mmol/L.In the case of normally taking medicine, continuous every day breakfast, lunch eat inventive formulation
2 months, normal diet was pressed in dinner.Through hospital, result of laboratory test again is as follows: urine protein is 1.8g/L (urine protein 2+), serum creatinine
For: 295umol/L, blood urea nitrogen is 12.8mmol/L.As can be seen here, it is eaten for a long time inventive formulation there is prevention and correct chronic
The relevant symptom of nephropathy, sign and complication effect.
Embodiment 2
The food composition that a kind of applicable Patients with Chronic Renal Disease is taken, including the component of following weight portion:
Amylum Nelumbinis Rhizomatis 180 parts, tapioca flour 250 parts, wheaten starch 250 parts, corn starch 200 parts, Semen setariae 30 parts, fructus zizaniae caduciflorae 40 parts,
Semen Coicis 10 parts, Semen Phaseoli 50 parts, Rhizoma Dioscoreae 50 parts, Semen Euryales 50 parts, Rhizoma amorphophalli 55 parts, Semen Castaneae 20 parts, Semen Sesami Nigrum 30 parts, Semen sojae atricolor Semen Sojae Preparatum 30
Part, 5 parts of Lentinus Edodes, Fructus Mori 15 parts, Semen Juglandis 30 parts, Fructus Lycii 25 parts, Fructus Jujubae 20 parts, dried Fructus Vitis viniferae 10 parts, wheat-germ meal 25 parts, powder of Radix Puerariae
50 parts, Fructus Crataegi powder 10 parts, tomato powder 30 parts, Radix Dauci Sativae powder 15 parts, concentrated lactoalbumin 98.5 parts, 78.5 parts of olive oil, Folium Perillae
Seed oil 13 parts, Semen Maydis oil 55 parts, maltodextrin 85 parts, VBT 18 parts, L MALIC ACID 15 parts, calcium acetate 10 parts.
The preparation method of the food composition that above-mentioned applicable Patients with Chronic Renal Disease is taken is as follows:
Each component is weighed according to above-mentioned consumption, by load weighted Semen setariae, fructus zizaniae caduciflorae, Semen Coicis, Semen Phaseoli, Rhizoma Dioscoreae, Semen Euryales,
Rhizoma amorphophalli, Semen Castaneae, Semen Sesami Nigrum, clean respectively, cook, hot-air seasoning；Load weighted Lentinus Edodes cleaned, cook, hot-air seasoning, and use
Ultraviolet irradiates or tans by the sun in the sun one hour；Above-mentioned raw materials is all ground into fine powder；By load weighted Semen sojae atricolor Semen Sojae Preparatum,
Fructus Mori, Semen Juglandis, Fructus Lycii, Fructus Jujubae, dried Fructus Vitis viniferae, also it is ground into fine powder；By load weighted maltodextrin 37 parts olive oil, Fructus Perillae
Oil, Semen Maydis oil, it is spray-dried and makes powder；By load weighted Amylum Nelumbinis Rhizomatis, tapioca flour, wheaten starch, corn starch, wheat-germ meal,
Powder of Radix Puerariae, Fructus Crataegi powder, tomato powder, Radix Dauci Sativae powder, concentrated lactoalbumin, maltodextrin 48 parts, VBT, L MALIC ACID, acetic acid
Calcium；Various components are put into three-dimensional mixer mixing 20min；After mix homogeneously standby；Mixed material is added high speed wet method system
Grain machine；Open High-Speed Automatic wet granulator, add and be pressed in 0.65pa；Raw material is stirred by speed governing degree to 18r/min；By 1kg
Raw material adds the ratio of 110ml pure water and accurately measures the required water yield, and after mixing 3 minutes, speed governing degree to 33r/min carries out granule
Cutting 15min；It is further continued for afterwards stirring raw material 6 minutes；Open outlet valve, collect granulation raw material, send drying workshop；By defective
Product is added to treat that granulation raw material is pelletized again；Granulation product is put into the drying baker that temperature is 46 DEG C and carries out drying and processing
2.5h；Pour the 30 mesh products dried into vibrations sieving machine, carry out granulate and sieve；Collect qualified products, prepare suitable
Close Patients with Chronic Renal Disease and food composition balanced in nutrition.
Song, female, 36 years old, suffers from chronic nephropathy 5 years.Through chemical examination, urine protein is 1.7g/L (urine protein 2+), and serum creatinine is:
98/L, blood urea nitrogen is 6.8mmol/L.In the case of normally taking medicine, continuous every day lunch, dinner eat inventive formulation 2 months,
Normal diet pressed by breakfast.Through hospital, result of laboratory test again is as follows: 1.2g/L (urine protein 2+), serum creatinine is: 79umol/L, carbamide
Nitrogen is 6.4mmol/L.As can be seen here, it is eaten for a long time inventive formulation there is prevention and correct the relevant symptom of chronic kidney disease, body
Complication of seeking peace effect.
Embodiment 3
The food composition that a kind of applicable Patients with Chronic Renal Disease is taken, including the component of following weight portion: Amylum Nelumbinis Rhizomatis 250 parts,
Tapioca flour 100 parts, wheaten starch 250 parts, corn starch 250 parts, Semen setariae 40 parts, fructus zizaniae caduciflorae 50 parts, Semen Coicis 20 parts, Semen Phaseoli 40
Part, Rhizoma Dioscoreae 30 parts, Semen Euryales 50 parts, Rhizoma amorphophalli 55 parts, Semen Castaneae 40 parts, Semen Sesami Nigrum 25 parts, 30 parts of Semen sojae atricolor Semen Sojae Preparatum, 10 parts of Lentinus Edodes, Fructus Mori
10 parts, Semen Juglandis 20 parts, Fructus Lycii 30 parts, Fructus Jujubae 25 parts, dried Fructus Vitis viniferae 15 parts, wheat-germ meal 50 parts, powder of Radix Puerariae 40 parts, Fructus Crataegi powder 30
Part, tomato powder 30 parts, Radix Dauci Sativae powder 20 parts, concentrated lactoalbumin 93 parts, 75.4 parts of olive oil, Oleum Perillae 13 parts, Semen Maydis oil
55 parts, maltodextrin 66.5 parts, VBT 20 parts, L MALIC ACID 14 parts, calcium acetate 11 parts.
The preparation method of the food composition that above-mentioned applicable Patients with Chronic Renal Disease is taken is as follows:
Each component is weighed according to above-mentioned consumption, by load weighted Semen setariae, fructus zizaniae caduciflorae, Semen Coicis, Semen Phaseoli, Rhizoma Dioscoreae, Semen Euryales,
Rhizoma amorphophalli, Semen Castaneae, Semen Sesami Nigrum, clean respectively, cook, hot-air seasoning；Load weighted Lentinus Edodes cleaned, cook, hot-air seasoning, and use
Ultraviolet irradiates or tans by the sun in the sun one hour；Above-mentioned raw materials is all ground into fine powder；By load weighted Semen sojae atricolor Semen Sojae Preparatum,
Fructus Mori, Semen Juglandis, Fructus Lycii, Fructus Jujubae, dried Fructus Vitis viniferae, also it is ground into fine powder；By load weighted maltodextrin 37 parts olive oil, Fructus Perillae
Oil, Semen Maydis oil, it is spray-dried and makes powder；By load weighted Amylum Nelumbinis Rhizomatis, tapioca flour, wheaten starch, corn starch, wheat-germ meal,
Powder of Radix Puerariae, Fructus Crataegi powder, tomato powder, Radix Dauci Sativae powder, concentrated lactoalbumin, maltodextrin 29.5 parts, VBT, L MALIC ACID, vinegar
Acid calcium；Various components are put into three-dimensional mixer mixing 10-20min；After mix homogeneously standby；Mixed material is added high speed wet
Method granulator；Open High-Speed Automatic wet granulator, add and be pressed in 0.65pa；Raw material is stirred by speed governing degree to 18r/min；Press
1kg raw material adds the ratio of 70ml pure water and accurately measures the required water yield, and after mixing 2.5 minutes, speed governing degree enters to 27r/min
Row granule cutting 27min；It is further continued for afterwards stirring raw material 4 minutes；Open outlet valve, collect granulation raw material, send drying workshop；Will
Substandard product is added to treat that granulation raw material is pelletized again；Granulation product is put into the drying baker that temperature is 43 DEG C carry out at drying
Reason 2.5h；Pour the 30 mesh products dried into vibrations sieving machine, carry out granulate and sieve；Collect qualified products, prepare
It is suitable for Patients with Chronic Renal Disease and food composition balanced in nutrition.
Liu, man, 47 years old, suffers from chronic nephropathy 4 years.Through chemical examination, urine protein is 3.3g/L (urine protein 3+), and serum creatinine is:
413umol/L, blood urea nitrogen is 13.8mmol/L.In the case of normally taking medicine, continuous every day breakfast, dinner eat inventive formulation
2 months, normal diet pressed by lunch.Through hospital, result of laboratory test again is as follows: urine protein is 1.7g/L (urine protein 2+), serum creatinine
For: 274umol/L, blood urea nitrogen is 11.4mmol/L.As can be seen here, it is eaten for a long time inventive formulation there is prevention and correct chronic
The relevant symptom of nephropathy, sign and complication effect.
Embodiment 4
The food composition that a kind of applicable Patients with Chronic Renal Disease is taken, including the component of following weight portion:
Amylum Nelumbinis Rhizomatis 250 parts, tapioca flour 200 parts, wheaten starch 160 parts, corn starch 250 parts, Semen setariae 40 parts, fructus zizaniae caduciflorae 50 parts,
Semen Coicis 10 parts, Semen Phaseoli 20 parts, Rhizoma Dioscoreae 50 parts, Semen Euryales 40 parts, Rhizoma amorphophalli 55 parts, Semen Castaneae 30 parts, Semen Sesami Nigrum 30 parts, Semen sojae atricolor Semen Sojae Preparatum 40
Part, 5 parts of Lentinus Edodes, Fructus Mori 10 parts, Semen Juglandis 40 parts, Fructus Lycii 30 parts, Fructus Jujubae 15 parts, dried Fructus Vitis viniferae 30 parts, wheat-germ meal 30 parts, powder of Radix Puerariae
50 parts, Fructus Crataegi powder 25 parts, tomato powder 40 parts, Radix Dauci Sativae powder 15 parts, concentrated lactoalbumin 96.7 parts, 73 parts of olive oil, Fructus Perillae
Oil 9.5 parts, Semen Maydis oil 50 parts, maltodextrin 63 parts, VBT 15 parts, L MALIC ACID 29.5 parts, calcium acetate 9 parts, with above-mentioned respectively
The total amount meter of individual raw material, this food composition also includes 4g/kg plant sterol, 2.2g/kg oligomeric xylose, the oligomeric shell of 0.9g/kg
Polysaccharide, the tea polyphenols of 0.2g/kg, the vitamin C of 150mg/kg, the vitamin B1 of 1.5mg/kg, the vitamin B2 of 2mg/kg,
The vitamin B6 of 3mg/kg, the nicotinic acid of 20mg/kg, the folic acid of 0.8mg/kg.
The preparation method of the food composition that above-mentioned applicable Patients with Chronic Renal Disease is taken is as follows:
Each component is weighed according to above-mentioned consumption, by load weighted Semen setariae, fructus zizaniae caduciflorae, Semen Coicis, Semen Phaseoli, Rhizoma Dioscoreae, Semen Euryales,
Rhizoma amorphophalli, Semen Castaneae, Semen Sesami Nigrum, clean respectively, cook, hot-air seasoning；Load weighted Lentinus Edodes cleaned, cook, hot-air seasoning, and use
Ultraviolet irradiates or tans by the sun in the sun one hour；Above-mentioned raw materials is all ground into fine powder；By load weighted Semen sojae atricolor Semen Sojae Preparatum,
Fructus Mori, Semen Juglandis, Fructus Lycii, Fructus Jujubae, dried Fructus Vitis viniferae, also it is ground into fine powder；By load weighted maltodextrin olive oil, Oleum Perillae,
Semen Maydis oil, is spray-dried and makes powder；By load weighted Amylum Nelumbinis Rhizomatis, tapioca flour, wheaten starch, corn starch, wheat-germ meal, Pueraria lobota
Root powder, Fructus Crataegi powder, tomato powder, Radix Dauci Sativae powder, concentrated lactoalbumin, maltodextrin, VBT, L MALIC ACID, calcium acetate；Will
Various components put into three-dimensional mixer, are simultaneously introduced plant sterol, oligomeric xylose, oligo-chitosan, tea polyphenols, vitamin C, dimension
Raw element B1, vitamin B2, vitamin B6, nicotinic acid, folic acid, mix 18min；After mix homogeneously standby；Mixed material is added height
Speed wet granulator；Open High-Speed Automatic wet granulator, add and be pressed in 0.65pa；Raw material is stirred by speed governing degree to 18r/min
Mix；The ratio adding 90ml pure water in 1kg raw material accurately measures the required water yield, after mixing 2 minutes, and speed governing degree to 27r/min
Carry out granule cutting 18min；It is further continued for afterwards stirring raw material 5 minutes；Open outlet valve, collect granulation raw material, send drying workshop；
It is added to substandard product treat that granulation raw material is pelletized again；Granulation product is put into the drying baker that temperature is 45 DEG C dry
Process 2.5h；Pour the 30 mesh products dried into vibrations sieving machine, carry out granulate and sieve；Collect qualified products, be prepared into
To being suitable for Patients with Chronic Renal Disease and food composition balanced in nutrition.
Grandson, man, 33 years old, suffers from chronic nephropathy 3 years.Through chemical examination, urine protein is 1.7g/L (urine protein 2+), and serum creatinine is:
286umol/L, blood urea nitrogen is 10.6mmol/L.In the case of normally taking medicine, continuous every day lunch, dinner eat inventive formulation
2 months, normal diet pressed by breakfast.Through hospital, result of laboratory test again is as follows: urine protein is 0.8g/L (urine protein 1+), serum creatinine
For: 179umol/L, blood urea nitrogen is 8.7mmol/L.As can be seen here, it is eaten for a long time inventive formulation there is prevention and correct chronic
The relevant symptom of nephropathy, sign and complication effect.
Embodiment 5
The food composition that a kind of applicable Patients with Chronic Renal Disease is taken, including the component of following weight portion:
Amylum Nelumbinis Rhizomatis 250 parts, tapioca flour 250 parts, wheaten starch 250 parts, corn starch 100 parts, Semen setariae 20 parts, fructus zizaniae caduciflorae 20 parts,
Semen Coicis 40 parts, Semen Phaseoli 50 parts, Rhizoma Dioscoreae 30 parts, Semen Euryales 50 parts, Rhizoma amorphophalli 50 parts, Semen Castaneae 50 parts, Semen Sesami Nigrum 30 parts, Semen sojae atricolor Semen Sojae Preparatum 40
Part, 10 parts of Lentinus Edodes, Fructus Mori 20 parts, Semen Juglandis 20 parts, Fructus Lycii 20 parts, Fructus Jujubae 25 parts, dried Fructus Vitis viniferae 30 parts, wheat-germ meal 45 parts, Radix Puerariae
20 parts of powder, Fructus Crataegi powder 30 parts, tomato powder 40 parts, Radix Dauci Sativae powder 15 parts, concentrated lactoalbumin 86 parts, 77 parts of olive oil, Fructus Perillae
Oil 12.8 parts, Semen Maydis oil 51 parts, maltodextrin 74.5 parts, VBT 25 parts, L MALIC ACID 19 parts, calcium acetate 10 parts, with above-mentioned
The total amount meter of each raw material, this food composition also includes that 4g/kg plant sterol, 2.2g/kg oligomeric xylose, 0.9g/kg are oligomeric
Chitosan, the tea polyphenols of 0.2g/kg, the vitamin C of 150mg/kg, the vitamin B1 of 1.5mg/kg, the vitamin B2 of 2mg/kg,
The vitamin B6 of 3mg/kg, the nicotinic acid of 20mg/kg, the folic acid of 0.8mg/kg.
Preparation method is with embodiment 4.
Lee, man, 51 years old, suffers from chronic nephropathy 11 years.Through chemical examination, urine protein is 5.2g/L (urine protein 4+), and serum creatinine is:
764umol/L, blood urea nitrogen is 19.8mmol/L.In the case of normally taking medicine, continuous every day breakfast, dinner eat inventive formulation
2 months, normal diet pressed by lunch.Through hospital, result of laboratory test again is as follows: urine protein is 3.0g/L (urine protein 3+), serum creatinine
For: 474umol/L, blood urea nitrogen is 14.7mmol/L.As can be seen here, it is eaten for a long time inventive formulation there is prevention and correct chronic
The relevant symptom of nephropathy, sign and complication effect.
Embodiment 6
The food composition that a kind of applicable Patients with Chronic Renal Disease is taken, including the component of following weight portion:
Amylum Nelumbinis Rhizomatis 100 parts, tapioca flour 250 parts, wheaten starch 250 parts, corn starch 250 parts, Semen setariae 30 parts, fructus zizaniae caduciflorae 50 parts,
Semen Coicis 30 parts, Semen Phaseoli 40 parts, Rhizoma Dioscoreae 40 parts, Semen Euryales 40 parts, Rhizoma amorphophalli 55 parts, Semen Castaneae 40 parts, Semen Sesami Nigrum 25 parts, Semen sojae atricolor Semen Sojae Preparatum 30
Part, 10 parts of Lentinus Edodes, Fructus Mori 15 parts, Semen Juglandis 40 parts, Fructus Lycii 25 parts, Fructus Jujubae 30 parts, dried Fructus Vitis viniferae 20 parts, wheat-germ meal 50 parts, Radix Puerariae
20 parts of powder, Fructus Crataegi powder 20 parts, tomato powder 25 parts, Radix Dauci Sativae powder 20 parts, concentrated lactoalbumin 84.5 parts, 76 parts of olive oil, Folium Perillae
Seed oil 10 parts, Semen Maydis oil 53.1 parts, maltodextrin 82 parts, VBT 21 parts, L MALIC ACID 20 parts, calcium acetate 9 parts, with above-mentioned respectively
The total amount meter of individual raw material, this food composition also includes 4g/kg plant sterol, 2.2g/kg oligomeric xylose, the oligomeric shell of 0.9g/kg
Polysaccharide, the tea polyphenols of 0.2g/kg, the vitamin C of 150mg/kg, the vitamin B1 of 1.5mg/kg, the vitamin B2 of 2mg/kg,
The vitamin B6 of 3mg/kg, the nicotinic acid of 20mg/kg, the folic acid of 0.8mg/kg.
Preparation method is with embodiment 4.
Zhao, man, 56 years old, suffers from chronic nephropathy 14 years.Through chemical examination, urine protein is 3.5g/L (urine protein 3+), and serum creatinine is:
577umol/L, blood urea nitrogen is 16.7mmol/L.In the case of normally taking medicine, continuous every day lunch, dinner eat inventive formulation
2 months, normal diet pressed by breakfast.Through hospital, result of laboratory test again is as follows: urine protein is 2.3g/L (urine protein 3+), serum creatinine
For: 384umol/L, blood urea nitrogen is 13.6mmol/L.As can be seen here, it is eaten for a long time inventive formulation there is prevention and correct chronic
The relevant symptom of nephropathy, sign and complication effect.
Embodiment 7
The food composition that a kind of applicable Patients with Chronic Renal Disease is taken, including the component of following weight portion:
Amylum Nelumbinis Rhizomatis 250 parts, tapioca flour 250 parts, wheaten starch 250 parts, corn starch 250 parts, Semen setariae 50 parts, fructus zizaniae caduciflorae 20 parts,
Semen Coicis 40 parts, Semen Phaseoli 20 parts, Rhizoma Dioscoreae 20 parts, Semen Euryales 30 parts, Rhizoma amorphophalli 65 parts, Semen Castaneae 20 parts, Semen Sesami Nigrum 20 parts, Semen sojae atricolor Semen Sojae Preparatum 30
Part, 5 parts of Lentinus Edodes, Fructus Mori 10 parts, Semen Juglandis 30 parts, Fructus Lycii 20 parts, Fructus Jujubae 20 parts, dried Fructus Vitis viniferae 10 parts, wheat-germ meal 25 parts, powder of Radix Puerariae
35 parts, Fructus Crataegi powder 10 parts, tomato powder 20 parts, Radix Dauci Sativae powder 10 parts, concentrated lactoalbumin 89 parts, 80 parts of olive oil, Oleum Perillae
12.4 parts, Semen Maydis oil 50 parts, maltodextrin 68 parts, VBT 20 parts, L MALIC ACID 21 parts, calcium acetate 10 parts；With above-mentioned each
The total amount meter of raw material, this food composition also includes 4g/kg plant sterol, 2.2g/kg oligomeric xylose, 0.9g/kg oligopolymerization chitosan
Sugar, the tea polyphenols of 0.2g/kg, the vitamin C of 150mg/kg, the vitamin B1 of 1.5mg/kg, the vitamin B2 of 2mg/kg, 3mg/
The vitamin B6 of kg, the nicotinic acid of 20mg/kg, the folic acid of 0.8mg/kg.
Luo, female, 43 years old, suffers from chronic nephropathy 9 years.Through chemical examination, urine protein is 3.2g/L (urine protein 3+), and serum creatinine is:
627umol/L, blood urea nitrogen is 15.1mmol/L.In the case of normally taking medicine, continuous every day breakfast, lunch eat inventive formulation
2 months, normal diet was pressed in dinner.Through hospital, result of laboratory test again is as follows: urine protein is 1.8g/L (urine protein 2+), serum creatinine
For: 451umol/L, blood urea nitrogen is 12.6mmol/L.As can be seen here, it is eaten for a long time inventive formulation there is prevention and correct chronic
The relevant symptom of nephropathy, sign and complication effect.
Preparation method is with embodiment 4.
Embodiment 8
The food composition that a kind of applicable Patients with Chronic Renal Disease is taken, including the component of following weight portion:
Amylum Nelumbinis Rhizomatis 250 parts, tapioca flour 250 parts, wheaten starch 250 parts, corn starch 250 parts, Semen setariae 40 parts, fructus zizaniae caduciflorae 40 parts,
Semen Coicis 20 parts, Semen Phaseoli 30 parts, Rhizoma Dioscoreae 30 parts, Semen Euryales 20 parts, Rhizoma amorphophalli 65 parts, Semen Castaneae 30 parts, Semen Sesami Nigrum 20 parts, Semen sojae atricolor Semen Sojae Preparatum 20
Part, 5 parts of Lentinus Edodes, Fructus Mori 10 parts, Semen Juglandis 30 parts, Fructus Lycii 20 parts, Fructus Jujubae 15 parts, dried Fructus Vitis viniferae 20 parts, wheat-germ meal 20 parts, powder of Radix Puerariae
40 parts, Fructus Crataegi powder 20 parts, tomato powder 10 parts, Radix Dauci Sativae powder 10 parts, concentrated lactoalbumin 94 parts, 80 parts of olive oil, Oleum Perillae
12 parts, Semen Maydis oil 52 parts, maltodextrin 66 parts, VBT 19 parts, L MALIC ACID 8.5 parts, calcium acetate 10 parts；Each is former with above-mentioned
Material total amount meter, this food composition also include 4g/kg plant sterol, 2.2g/kg oligomeric xylose, 0.9g/kg oligo-chitosan,
The tea polyphenols of 0.2g/kg, the vitamin C of 150mg/kg, the vitamin B1 of 1.5mg/kg, the vitamin B2 of 2mg/kg, 3mg/kg
Vitamin B6, the nicotinic acid of 20mg/kg, the folic acid of 0.8mg/kg.
Preparation method is with embodiment 4.
Jiang, female, 62 years old, suffers from chronic nephropathy 12 years.Through chemical examination, urine protein is 3.4g/L (urine protein 3+), and serum creatinine is:
813umol/L, blood urea nitrogen is 19.2mmol/L.In the case of normally taking medicine, continuous every day breakfast, lunch, dinner all edible this
Invention formula 2 months.Through hospital, result of laboratory test again is as follows: urine protein is 2.1g/L (urine protein 3+), and serum creatinine is:
546umol/L, blood urea nitrogen is 14.8mmol/L.As can be seen here, it is eaten for a long time inventive formulation there is prevention and correct chronic renal
The relevant symptom of disease of ZANG-organs, sign and complication effect.
The technique effect of the present invention is described below in conjunction with concrete zoopery:
One, the therapeutical effect to STZ modeling adriamycin-induced nephropathy in Wistar rats
1, test material
1.1 animals:
Cleaning grade male SD rat 90, body weight 200～220g is purchased from Beijing dimension tonneau China limited public affairs of laboratory animal technology
Department.
1.2 reagent and medicine:
Streptozotocin (STZ) is purchased from Sigma Co., USA, makes with the 0.01mmol/ml citrate buffer of pH4.2
The STZ solution of 8mg/ml；Instrument for Measuring Blood Sugar and reagent paper are provided by Johnson & Johnson (Chinese) company limited；Blood glucose (BG), carbamide (Urea),
The biochemical reagents such as creatinine (Cr) are purchased from Beijing Zhong Kongzhongsheng biological reagent company；Microdose urine protein (mAlb) measures reagent and is purchased from
Shanghai Sun Bio-Tech Co., Ltd.；Captopril, Shanghai Shi Guibao pharmaceutical Co. Ltd of Sino-U.S..
2 methods
The foundation of 2.1 animal models and packet:
Diabetic nephropathy animal model, normal control is prepared with the STZ citron acid solution buffer intraperitoneal injection of 45mg/kg
Group lumbar injection equivalent citrate buffer.Injection 72h after, rat tail vein survey blood glucose > 16.6mmol/L be modeling success.Dynamic
Thing is randomly divided into 5 groups by blood glucose value, often group 8: Normal group, diabetic nephropathy model group, Captopril group, this diet group
Compound group.
Each group of experiment mice is put into Mouse feeder cage feed, four, every cage, experimentation small mouse freely ingest and
Drinking-water, the body weight of every two days record mices and food ration, feed 5 weeks continuously.Animal feeding chamber temperature 23 ± 2 DEG C, 12:12h is bright
Dark being alternately placed in metabolic cage, leave and take 24h urine, after weighing next day, femoral artery takes blood, separates serum, and blood, Urine specimens-
20 DEG C preserve standby survey.Take kidney of rats to weigh, ice bath takes renal cortex, put in 10% formalin fixing.
2.2 observation index:
Blood, urine Biochemical Indexes carry out time-and-motion study by test kit description；Relative kidney index is the ratio of kidney weight and body weight.
Kidney carries out the dyeing of conventional H E and dyes with glycogen PAS.PAS dyeing pathology carries out semi-quantitative analysis: under light microscopic, blind is observed, and takes
PAS stained, carries out semi-quantitative analysis, and every part of specimen is observed 10 glomerule, calculated glomerular basement membrane and mesangial region face
Long-pending when Capillary loops and mesangial region area ratio, take average ratio relatively.
3 statistical analysiss
Determination data represents with X ± s, uses t inspection.
4. experimental result
4.1 impacts on STZ diabetic nephropathy function Yu microdose urine protein
Persistent high blood sugar after 5 weeks in diabetic nephropathy model control rats blood Ure, blood Cr and urine in mALB/Cr notable
Raise (p ＜ 0.01).Captopril group, this food composition group feeding after 5 weeks in blood in Ure, blood Cr (SCr) and urine in mALB/
Cr is all substantially less than model control group (p < 0.01 or p ＜ 0.05).
The table 1 (X ± s) on STZ diabetic nephropathy function Yu the impact of microdose urine protein
##P < 0.01 and Normal group ratio；p<0.05；* p ＜ 0.01 and model control group ratio.
4.2 impacts on STZ diabetic nephropathy index
Persistent high blood sugar is diabetic nephropathy model kidney of rats index rising (p < 0.01) after 5 weeks.After feeding 5 weeks, block Top
Profit has certain inhibitory action to renal index, but there was no significant difference (p > 0.05), and renal index is had bright by this food composition
Aobvious inhibitory action (p < 0.05).
The impact (X=s) of table 2 index dirty on STZ diabetic nephropathy
##P ＜ 0.01 compares with Normal group, and * P ＜ 0.05 compares with model control group.
The impact of 4.3 pathological changes dirty on STZ diabetic nephropathy
After testing 5 weeks, the glomerular mesangium district diffusivity of diabetic nephropathy model matched group is broadening, extracellular matrix increases, portion
Point glomerule occur the homogeneous proteinous material of PAS stained positive, glomerular endothelial cells without showed increased, tubule-interstitial without
Substantially pathological change, the change of Captopril group, this food composition group Pathological is substantially lighter than diabetic model group.Nephropathy
Reason image semi-quantitative analysis shows: the glomerular basement membrane of diabetic nephropathy model group/mesangial region area ratio is significantly greater than normal
Matched group, Capillary loops/mesangial region area ratio is significantly less than Normal group；Each administration group glomerular basement membrane/mesangial region
Area ratio is less than diabetic nephropathy model group, and Capillary loops/mesangial region area ratio is then more than model group；Each administration group is with normal
Matched group is compared, and changes inconspicuous.
5. conclusion
Experimental result shows that this food composition group can be improved modeling animal renal function, reduce albuminuria, alleviates glomerule
High filtration, suppression renal hypertrophy, suppression extracellular matrix increase, the early nephropathy to STZ induced diabetes nephrotic rats
There is significant preventive and therapeutic effect.
Described above illustrate and describes some preferred embodiments of invention, but as previously mentioned, it should be understood that invention is not
It is confined to form disclosed herein, is not to be taken as the eliminating to other embodiments, and can be used for other combinations various, amendment
And environment, and can be carried out by above-mentioned teaching or the technology of association area or knowledge in invention contemplated scope described herein
Change.And the change that those skilled in the art are carried out and change are without departing from the spirit and scope of invention, the most all should weigh appended by invention
In the protection domain that profit requires.
Claims (5)
1. the food composition that an applicable Patients with Chronic Renal Disease is taken, it is characterised in that include following components according to weight portion:
Lotus root congee 100-250 part, tapioca flour 100-250 part, wheaten starch 100-250 part, corn starch 100-250 part, Semen setariae 20-50
Part, fructus zizaniae caduciflorae 20-50 part, Semen Coicis 10-40 part, Semen Phaseoli 20-50 part, Rhizoma Dioscoreae 20-50 part, Semen Euryales 20-50 part, Rhizoma amorphophalli 50-65 part,
Semen Castaneae 20-50 part, Semen Sesami Nigrum 20-30 part, Semen sojae atricolor Semen Sojae Preparatum 20-40 part, Lentinus Edodes 5-10 part, Fructus Mori 10-20 part, Semen Juglandis 20-40 part,
Fructus Lycii 20-30 part, Fructus Jujubae 15-30 part, dried Fructus Vitis viniferae 10-30 part, wheat-germ meal 20-50 part, powder of Radix Puerariae 20-50 part, Fructus Crataegi powder 10-
30 parts, tomato powder 10-40 part, Radix Dauci Sativae powder 10-20 part, concentrated lactoalbumin 84.5-98.5 part, olive oil 73-80 part, purple
Fructus Perillae oil 9.5-13 part, Semen Maydis oil 50-55 part, maltodextrin 63-85 part, VBT 15-25 part, L MALIC ACID 8.5-29.5
Part, calcium acetate 9-11 part.
The food composition that applicable Patients with Chronic Renal Disease the most according to claim 1 is taken, it is characterised in that want with right
Seeking the weight total amount meter of each component in 1, this applicable Patients with Chronic Renal Disease and food composition balanced in nutrition also include following
Component: 4g/kg plant sterol, 2.2g/kg oligomeric xylose, 0.9g/kg oligo-chitosan, the tea polyphenols of 0.2g/kg, 150mg/kg
Vitamin C, the vitamin B1 of 1.5mg/kg, the vitamin B2 of 2mg/kg, the vitamin B6 of 3mg/kg, the nicotinic acid of 20mg/kg,
The folic acid of 0.8mg/kg.
The food composition that applicable Patients with Chronic Renal Disease the most according to claim 1 and 2 is taken, it is characterised in that enter one
Step ground, this food composition includes following components according to weight portion: Amylum Nelumbinis Rhizomatis 100-250 part, tapioca flour 100-250 part, Semen Tritici aestivi forms sediment
Powder 100-250 part, corn starch 100-250 part, Semen setariae 20-50 part, fructus zizaniae caduciflorae 20-50 part, Semen Coicis 10-40 part, Semen Phaseoli 20-50
Part, Rhizoma Dioscoreae 20-50 part, Semen Euryales 20-50 part, Rhizoma amorphophalli 50-65 part, Semen Castaneae 20-50 part, Semen Sesami Nigrum 20-30 part, Semen sojae atricolor Semen Sojae Preparatum 20-
40 parts, Lentinus Edodes 5-10 part, Fructus Mori 10-20 part, Semen Juglandis 20-40 part, Fructus Lycii 20-30 part, Fructus Jujubae 15-30 part, dried Fructus Vitis viniferae 10-30
Part, wheat-germ meal 20-50 part, powder of Radix Puerariae 20-50 part, Fructus Crataegi powder 10-30 part, tomato powder 10-40 part, Radix Dauci Sativae powder 10-20
Part, concentrated lactoalbumin 84.5-98.5 part, olive oil 73-80 part, Oleum Perillae 9.5-13 part, Semen Maydis oil 50-55 part, Fructus Hordei Germinatus
Dextrin 63-85 part, VBT 15-25 part, L MALIC ACID 8.5-29.5 part, calcium acetate 9-11 part.
4. the preparation method of the food composition that an applicable Patients with Chronic Renal Disease is taken, it is characterised in that comprise the following steps:
1) weigh: according to mass parts weighing following components:
Amylum Nelumbinis Rhizomatis 100-250 part, tapioca flour 100-250 part, wheaten starch 100-250 part, corn starch 100-250 part, Semen setariae 20-
50 parts, fructus zizaniae caduciflorae 20-50 part, Semen Coicis 10-40 part, Semen Phaseoli 20-50 part, Rhizoma Dioscoreae 20-50 part, Semen Euryales 20-50 part, Rhizoma amorphophalli 50-65
Part, Semen Castaneae 20-50 part, Semen Sesami Nigrum 20-30 part, Semen sojae atricolor Semen Sojae Preparatum 20-40 part, Lentinus Edodes 5-10 part, Fructus Mori 10-20 part, Semen Juglandis 20-40
Part, Fructus Lycii 20-30 part, Fructus Jujubae 15-30 part, dried Fructus Vitis viniferae 10-30 part, wheat-germ meal 20-50 part, powder of Radix Puerariae 20-50 part, Fructus Crataegi powder
10-30 part, tomato powder 10-40 part, Radix Dauci Sativae powder 10-20 part, concentrated lactoalbumin 84.5-98.5 part, olive oil 73-80 part,
Oleum Perillae 9.5-13 part, Semen Maydis oil 50-55 part, maltodextrin 63-85 part, VBT 15-25 part, L MALIC ACID 8.5-29.5
Part, calcium acetate 9-11 part；
2) by load weighted Semen setariae, fructus zizaniae caduciflorae, Semen Coicis, Semen Phaseoli, Rhizoma Dioscoreae, Semen Euryales, Rhizoma amorphophalli, Semen Castaneae, Semen Sesami Nigrum, clean respectively, steam
Ripe, hot-air seasoning；Load weighted Lentinus Edodes cleaned, cook, hot-air seasoning, and irradiate with ultraviolet or tan by the sun one in the sun
Hour；Above-mentioned raw materials is all ground into fine powder；
3) by load weighted Semen sojae atricolor Semen Sojae Preparatum, Fructus Mori, Semen Juglandis, Fructus Lycii, Fructus Jujubae, dried Fructus Vitis viniferae, fine powder also it is ground into；
4) by load weighted maltodextrin 33.5-37 part olive oil, Oleum Perillae, Semen Maydis oil, it is spray-dried and makes powder；
5) by load weighted Amylum Nelumbinis Rhizomatis, tapioca flour, wheaten starch, corn starch, wheat-germ meal, powder of Radix Puerariae, Fructus Crataegi powder, Fructus Lycopersici esculenti
Powder, Radix Dauci Sativae powder, concentrated lactoalbumin, maltodextrin 29.5-48 part, VBT, L MALIC ACID, calcium acetate；
6) by step 1)-step 5) weigh the various components that obtain and put into three-dimensional mixer mixing 10-20min；After mix homogeneously
Standby；
7) by step 6) mixed material that obtains adds high speed wet granulator；Open High-Speed Automatic wet granulator, add and be pressed in
0.65pa；Raw material is stirred by speed governing degree to 18r/min；The ratio correct amount of 40-110ml pure water is added in 1kg raw material
Taking institute's water requirement, after mixing 2-3 minute, speed governing degree to 15-33r/min carries out granule cutting 15-33min；It is further continued for afterwards stirring
Mix raw material 3-6 minute；Open outlet valve, collect granulation raw material, send drying workshop；It is added to substandard product treat granulation raw material weight
New granulation；
8) drying and processing: by step 7) the granulation product that obtains puts into the drying baker that temperature is 40-46 DEG C and carries out drying and processing
2.5h；
9) granulate and sieving: pour the 30 mesh products dried into vibrations sieving machine, carry out granulate and sieve；Collect qualified product
Product, prepare applicable Patients with Chronic Renal Disease and food composition balanced in nutrition.
The preparation method of the food composition that applicable Patients with Chronic Renal Disease the most according to claim 4 is taken, its feature exists
In, described step 6) specifically implement according to following steps: by step 1)-step 5) after the various component mix homogeneously that obtain, with
Step 1)-step 5) the total amount meter of various components that obtains, further add 4g/kg plant sterol, the oligomeric wood of 2.2g/kg
Sugar, 0.9g/kg oligo-chitosan, the tea polyphenols of 0.2g/kg, the vitamin C of 150mg/kg, the vitamin B of 1.5mg/kg1、
The vitamin B of 2mg/kg2, the vitamin B of 3mg/kg6, the nicotinic acid of 20mg/kg, the folic acid of 0.8mg/kg, mix homogeneously, standby.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610362736.2A CN106036831A (en) | 2016-05-26 | 2016-05-26 | Food composition suitable for patients with chronic kidney diseases to eat and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610362736.2A CN106036831A (en) | 2016-05-26 | 2016-05-26 | Food composition suitable for patients with chronic kidney diseases to eat and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106036831A true CN106036831A (en) | 2016-10-26 |
Family
ID=57175488
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610362736.2A Pending CN106036831A (en) | 2016-05-26 | 2016-05-26 | Food composition suitable for patients with chronic kidney diseases to eat and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106036831A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107118927A (en) * | 2017-04-10 | 2017-09-01 | 任国亮 | A kind of Semen sesami nigrum Health-care fruit vinegar |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105285952A (en) * | 2015-10-29 | 2016-02-03 | 华海正元（福建）生物科技有限公司 | Meal replacement powder with balanced nutrients and preparation method of meal replacement powder |
-
2016
- 2016-05-26 CN CN201610362736.2A patent/CN106036831A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105285952A (en) * | 2015-10-29 | 2016-02-03 | 华海正元（福建）生物科技有限公司 | Meal replacement powder with balanced nutrients and preparation method of meal replacement powder |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107118927A (en) * | 2017-04-10 | 2017-09-01 | 任国亮 | A kind of Semen sesami nigrum Health-care fruit vinegar |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2019101804A4 (en) | Traditional Chinese medicine medical nutrition therapy-based composition for treating diabetes, and application | |
| CN102178144B (en) | Energy supplement food and preparation method thereof | |
| CN101156679B (en) | Rice bran nutrition stock solution and its preparation method | |
| CN105995993A (en) | Food composition applicable to diabetic and preparation method thereof | |
| CN104431741A (en) | Cereal conditioning porridge and making method and application thereof | |
| CN102860468A (en) | Corn composite nutritive rice | |
| CN101422239B (en) | Combined partner capable of increasing edible rice, flour nutrition | |
| JP2017529086A (en) | Optimal nutrition food | |
| CN106072519A (en) | A kind of plant fat-reducing ferment and preparation method thereof | |
| CN106376934A (en) | Ketogenic-diet composition containing active polysaccharide, and preparation and application methods thereof | |
| CN100444746C (en) | A refined health food of high and cold mountain area crop and processing technology thereof | |
| CN107125495A (en) | A kind of white crucian feed and preparation method thereof | |
| CN109170916A (en) | One kind keeps fit and healthy food compositions and preparation method thereof | |
| CN106036831A (en) | Food composition suitable for patients with chronic kidney diseases to eat and preparation method thereof | |
| JP2007029020A (en) | Black vinegar health food and method for producing the same | |
| CN106176952A (en) | A kind of health composition comprising leaf of Cyclocarya paliurus Iljinskaja and Folium Ilicis | |
| CN106261434A (en) | A kind of solid beverage with cosmetic slimming function containing inulin and preparation method thereof | |
| CN106307041A (en) | Production method of health-care rice noodles | |
| CN105918966A (en) | Dried sweet potato slices and preparation method thereof | |
| CN104187290B (en) | Coarse cereal leisure food providing energy and preparing method thereof | |
| CN103083590B (en) | A kind of medicine for treating cirrhosis patients in decompensation and preparation method | |
| CN104286384A (en) | Soybean straw feed for lambs and preparation method thereof | |
| CN103750494A (en) | Preparation method for health-care purple sweet potato granule | |
| CN104605354B (en) | A kind of shrimp claw plant health care nutrition powder and its preparation method | |
| CN107087783A (en) | A kind of production method of black rice resistant starch |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20170322 Address after: 350400 Fuzhou Province, Pingtan Province integrated experimentation area high-tech industrial center Applicant after: Gu Ruisen bio tech ltd, Fujian Applicant after: Kami Jungwon (Fujian) Biotechnology Co., Ltd. Address before: Cangshan District, Fuzhou City, Fujian Province, Kim Kang Road 350008 No. 41 pick 13 unit 101 Xian yuan Applicant before: Lin Xiting Applicant before: Ruan Tongna Applicant before: Ruan Jianzhong Applicant before: Lin Kaixi |
|
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20161026 |