CN106017995A - Sample tube for quantitatively collecting liquid - Google Patents
Sample tube for quantitatively collecting liquid Download PDFInfo
- Publication number
- CN106017995A CN106017995A CN201610603588.9A CN201610603588A CN106017995A CN 106017995 A CN106017995 A CN 106017995A CN 201610603588 A CN201610603588 A CN 201610603588A CN 106017995 A CN106017995 A CN 106017995A
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- China
- Prior art keywords
- inserted sheet
- tubule
- liquid
- liquid sample
- sample
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
- G01N1/14—Suction devices, e.g. pumps; Ejector devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
- G01N1/14—Suction devices, e.g. pumps; Ejector devices
- G01N2001/1472—Devices not actuated by pressure difference
- G01N2001/149—Capillaries; Sponges
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- Life Sciences & Earth Sciences (AREA)
- Hydrology & Water Resources (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention discloses a sample tube for quantitatively collecting liquid. The sample tube comprises a thin tube and a hydrophilic inserting piece, wherein the thin tube is used for collecting the liquid and storing the liquid; the thin tube is of a through cavity structure; the hydrophilic inserting piece is fixedly arranged in the thin tube; the edge of the hydrophilic inserting piece is in contact with the tube wall of the thin tube; a siphon structure is formed by the hydrophilic inserting piece and the thin tube; one end of the hydrophilic inserting piece is flush with an opening in one end of the thin tube; when one end of the hydrophilic inserting piece is in contact with the liquid, a liquid sample can be siphoned into the thin tube, the liquid can automatically stop when flowing to the other end of the hydrophilic inserting piece, the inner diameter of the thin tube and the length of the hydrophilic inserting piece can be regulated according to demands, control on sampling amount is realized, and the use is convenient.
Description
Technical field
The invention belongs to area of medical devices, be specifically related to a kind of sample tube for quantitative collection liquid.
Background technology
Trace gathers liquid sample accurately, has demand widely in diagnostic detection field.Such as bedside detection (Point of Care Testing) and field such as the application food safety detection of immunochromatography technique, environment measuring etc., accurately trace blood or other liquid-like instincts assist a physician or tester obtains testing result more accurately.On market, existing different company develops different micro quantitative determination blood samplings or the device of other liquid, such as Pasteur's dropper, at tube wall subscript high scale, quantitative sampling can be realized, but in gatherer process, the extruding power of pasteur pipet is difficult to control, particularly microsampling, such as 5 microlitres, 10 microlitres, Pasteur's dropper is difficult to operation, or needs the training of specialty；The most such as liquid-transfering gun, sample the most accurate, it is suitable for reusing, be not suitable for single use, high expensive, practical operation gets up to have the biggest challenge, for meeting the demand in market, need to develop a automatic ration with low cost and gather the product of micro liquid sample, be especially applicable to the sampling of immunochromatography detection platform.
Summary of the invention
The open a kind of sample tube application siphon principle of the present invention goes to realize automatic ration and gathers liquid sample.
The technical scheme is that a kind of quantitative collection liquid sample pipe, including:
One tubule, is used for gathering liquid and stores liquid in body, and described tubule is entire body cavity structure；
One hydrophilic inserted sheet, inserted sheet is arranged in tubule, and tab edge contacts with tubule tube wall, and inserted sheet forms syphon structure with tubule, and inserted sheet is concordant with tubule one end open.When inserted sheet end contacts with liquid, in meeting siphon liquid sample to tubule, liquid walks to the inserted sheet other end and is automatically stopped, and completes quantitative collection.Having gathered liquid sample, can have been contacted with the sample pad of immune chromatography test paper or other fluffy water wetted materials by inserted sheet end, sample will be sucked out automatically.
Preferably, described tubule one end is connected with a squeezable balloon-like structure, and described inserted sheet is arranged at the tubule other end, tab edge contacts with tubule tube wall, inserted sheet forms syphon structure with tubule, and inserted sheet is concordant with tubule port end, and described balloon-like structure is provided with passage.When inserted sheet end contacts with liquid, and passage is unimpeded, and in meeting siphon liquid sample to tubule, liquid walks to the inserted sheet other end and is automatically stopped, and completes quantitative collection.Having gathered liquid sample, can have been contacted with the sample pad of immune chromatography test paper by inserted sheet end, sample will be inhaled into sample pad automatically, or blocks passage with finger, and sample is extruded by extruding balloon-like structure.
Preferably, described tubule one end can heat sealing, and the liquid of fill designated volume, described tubule is sealed up for safekeeping liquid by liquid film, is provided with the trace that fractures at heat sealing end, and described inserted sheet is arranged at the tubule other end, tab edge contacts with tube wall, inserted sheet forms syphon structure with tubule, and inserted sheet is concordant with tubule port, is provided with passage between inserted sheet and liquid film.When inserted sheet end contacts with liquid, and passage is unimpeded, and in meeting siphon liquid sample to tubule, liquid walks to the inserted sheet other end and is automatically stopped, and completes quantitative collection.Having gathered liquid sample, can have been contacted with the sample pad of immune chromatography test paper by inserted sheet end, sample will be inhaled into sample pad automatically, and along fractureing, trace breaks disconnected tubule, and the liquid of encapsulation will flow out under gravity.
Preferably, adjustable capillary inside diameter and inserted sheet length realize the collection of designated volume liquid sample.
Preferably, described tubule is suitable with inserted sheet, and described tubule quantification gathers the liquid sample of designated volume.
Preferably, described inserted sheet is cuboid thin slice, and described inserted sheet cross sectional shape is monolithic or intersects biplate or multi-sheet structure.
Preferably, described tubule and inserted sheet are that transparent polymer material is made, it is simple to observe sampling quantity.
Quantitative collection liquid sample pipe of the present invention has the beneficial effect that
This application siphon strength automatic ration disclosed by the invention gathers trace sample pipe, overcomes above-mentioned difficulty completely, and can improve efficiency and the accuracy of detection of testing staff.The diluent of immune chromatograph testing platform also can be encapsulated in sample tube by the present invention, makes testing staff operate simpler.
Described tubule and inserted sheet all can be prepared through simple processing technique by common plastic material, such as tubule can or pull-out technique extruded by polystyrene or polypropylene, or polyethylene through blow molding process prepare；Inserted sheet can be made up of polyethylene terephthalate or polrvinyl chloride application expressing technique, and the cheap technique of these materials is simple, cheap for manufacturing cost.
Accompanying drawing explanation
Fig. 1 is the first structural representation of quantitative collection liquid sample pipe of the present invention.
Fig. 2 is the second structural representation of quantitative collection liquid sample pipe of the present invention.
Fig. 3 is the 3rd structural representation of quantitative collection liquid sample pipe of the present invention.
In figure: 1-tubule, 2-inserted sheet, 3-passage.
Detailed description of the invention
Below in conjunction with accompanying drawing, quantitative testing device of the present invention and detection method thereof are described in detail, it is impossible to be not understood as limitation of the present invention.
Embodiment one:
As shown in Figure 1:
Tubule 1 is prepared by transparent polypropylene plastic applications expressing technique, and inserted sheet 2 can be made up of transparent polyethylene terephthalate application expressing technique, and inserted sheet 2 is done hydrophilic and processes by the later stage.Inserted sheet width is slightly larger than capillary inside diameter, facilitates inserted sheet to be fixed in tubule.Such as to gather the finger tip blood sample of 5 microlitres, tubule can be with polypropylene material at extrusion machine extrusion 2 millimeters of internal diameters, tubules of wall thickness 0.15 millimeter, the sheet material of 0.3 millimeters thick is prepared by polyethylene terephthalate application expressing technique, do hydrophilic to process, cut out 2 millimeters of (plus tolerance 0.1 millimeter) square thin slices afterwards.Contacting with finger tip blood with the inserted sheet end of sample tube, blood sample, by being automatically inhaled in pipe, walks to the inserted sheet other end and is automatically stopped, and 5 microlitre finger tip blood collections complete.If application immunochromatography technique detects, directly being contacted with the sample pad of immune chromatography test paper by inserted sheet end, finger tip blood sample will be drawn onto in sample pad automatically.
Embodiment two:
As shown in Figure 2:
Tubule 1 and squeezable balloon-like structure are prepared by vinyon application blow molding process, and identical with Pasteur's dropper manufacturing process, passage 3 can be pricked out by fine needle.Inserted sheet manufacturing process is with embodiment one.Such as to gather the finger tip blood sample of 5 microlitres, prepare the dropper that opening part internal diameter is 2 mm outer diameter 2.6 millimeters, pricking on capsule has passage.When during sampling, inserted sheet end contacts with finger tip blood, and passage is unimpeded, and blood sample will be automatically drawn into tubule, and blood walks to the inserted sheet other end and is automatically stopped, and 5 microlitre finger tip blood collections complete.If application immunochromatography technique detects, having gathered blood sample, can have been contacted with the sample pad of immune chromatography test paper by inserted sheet end, sample will be drawn onto in sample pad automatically, or blocks passage with finger, gently expulsion bladder structure, and sample will be extruded.
Embodiment three:
As shown in Figure 3:
Described tubule 1 is made up of polypropylene plastics application bench, described tubule 1 one end heat sealing, and the liquid of fill designated volume, described tubule 1 is encapsulated by liquid film, being provided with the trace that fractures at heat sealing end, inserted sheet manufacturing process, with embodiment one, is provided with passage 3 between inserted sheet and liquid film.Such as to gather the finger tip blood sample of 5 microlitres, tubule is made up of polypropylene plastics application bench, external diameter 3.1mm, internal diameter 2.0mm, long 75 millimeters.The melted sealing in one end, carves, at sealing end 5mm, the trace that fractures, pours into the diluent of 0.14 milliliter, add 0.10 milliliter of silicone oil, centrifugal encapsulation.The length and width plus tolerance of inserted sheet, with embodiment one, is adjusted to 0.05 millimeter by inserted sheet manufacture method；Hole is pricked between inserted sheet and silicone oil liquid film.During sampling, inserted sheet end contacts with finger tip blood, and blood can be automatically drawn in pipe, walks to the inserted sheet other end and is automatically stopped, and 5 microlitres have been sampled.If application immunochromatography technique detects, having gathered blood sample, can have been contacted with the sample pad of immune chromatography test paper by inserted sheet end, blood sample will be drawn onto in sample pad automatically, and along fractureing, trace is broken disconnected, and diluent will assist in detection.
Claims (7)
1. a quantitative collection liquid sample pipe, including:
One tubule, for gathering liquid and storing the body of liquid, described tubule is entire body cavity structure；
One hydrophilic inserted sheet, inserted sheet is arranged in tubule, tab edge contacts with tubule tube wall, inserted sheet forms syphon structure with tubule, and inserted sheet is concordant with tubule one end open, when inserted sheet end contacts with liquid, siphon can enter liquid sample in tubule, liquid walks to the inserted sheet other end and is automatically stopped, and completes quantitative sampling, capillary inside diameter and inserted sheet length and is adjusted according to demand realizing sampling quantity control.
Quantitative collection liquid sample pipe the most according to claim 1, it is characterised in that: described tubule one end is connected with a squeezable balloon-like structure, and described inserted sheet is arranged at the suction pipe other end, and tab edge is concordant with suction pipe port, and described balloon-like structure is provided with passage.
Quantitative collection liquid sample pipe the most according to claim 1, it is characterized in that: described tubule one end heat sealing, and the liquid of fill designated volume, described tubule is sealed up for safekeeping the liquid of fill by liquid film, being provided with the trace that fractures at heat sealing end, described inserted sheet inserts the tubule other end, and tab edge contacts with tube wall, inserted sheet forms syphon structure with tube wall, and the tubule wall between inserted sheet and liquid film is provided with passage.
Quantitative collection liquid sample pipe the most according to claim 1, it is characterised in that: described tubule is suitable with inserted sheet, and capillary inside diameter and inserted sheet length determine to gather the liquid sample amount of designated volume.
Quantitative collection liquid sample pipe the most according to claim 1, it is characterised in that: described inserted sheet is cuboid thin slice.
Quantitative collection liquid sample pipe the most according to claim 1, it is characterised in that: described inserted sheet cross sectional shape is monolithic or intersects biplate or multi-sheet structure.
Quantitative collection liquid sample pipe the most according to claim 1, it is characterised in that: described tubule and inserted sheet are that transparent polymer material is made, it is simple to observe sampling performance.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610603588.9A CN106017995A (en) | 2016-07-27 | 2016-07-27 | Sample tube for quantitatively collecting liquid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610603588.9A CN106017995A (en) | 2016-07-27 | 2016-07-27 | Sample tube for quantitatively collecting liquid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106017995A true CN106017995A (en) | 2016-10-12 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610603588.9A Pending CN106017995A (en) | 2016-07-27 | 2016-07-27 | Sample tube for quantitatively collecting liquid |
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| CN (1) | CN106017995A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107570248A (en) * | 2017-08-28 | 2018-01-12 | 宁夏软件工程院有限公司 | A kind of liquid level sampling pipette |
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| CN201364338Y (en) * | 2008-12-20 | 2009-12-16 | 孔庆玲 | Novel sampling dropper |
| US20110212482A1 (en) * | 2010-02-12 | 2011-09-01 | Northwestern University | Methods and devices for sample collection, treatment and dispensing |
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| CN103983766A (en) * | 2014-04-16 | 2014-08-13 | 南京奥康生物技术有限公司 | Detection apparatus for quantitatively sampling samples, and detection method thereof |
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| CN203943678U (en) * | 2014-04-10 | 2014-11-19 | 苏州天亮工程塑业有限公司 | The quantitative micro blood-taking tube of disposable use |
| CN205126255U (en) * | 2015-11-17 | 2016-04-06 | 东台市科华医疗器械有限公司 | High accuracy ration micro blood collection pipette |
| CN205175737U (en) * | 2015-10-27 | 2016-04-20 | 光景生物科技(苏州)有限公司 | Blood sampling external member |
| CN205958300U (en) * | 2016-07-27 | 2017-02-15 | 江苏奥罗生物诊断有限公司 | Liquid sample pipe is gathered to ration |
-
2016
- 2016-07-27 CN CN201610603588.9A patent/CN106017995A/en active Pending
Patent Citations (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2528394Y (en) * | 2001-11-29 | 2003-01-01 | 门月杰 | Disposable micro-hemostix |
| CN2566244Y (en) * | 2002-09-09 | 2003-08-13 | 赵超 | Sampler |
| US20070299365A1 (en) * | 2004-11-09 | 2007-12-27 | Calasso Irio G | Sampling system for sample fluid |
| CN201364338Y (en) * | 2008-12-20 | 2009-12-16 | 孔庆玲 | Novel sampling dropper |
| US20110212482A1 (en) * | 2010-02-12 | 2011-09-01 | Northwestern University | Methods and devices for sample collection, treatment and dispensing |
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| CN104116513A (en) * | 2013-04-23 | 2014-10-29 | 马荣华 | Self-priming type quantitative micro-quantity blood collection tube |
| CN203943678U (en) * | 2014-04-10 | 2014-11-19 | 苏州天亮工程塑业有限公司 | The quantitative micro blood-taking tube of disposable use |
| CN103983766A (en) * | 2014-04-16 | 2014-08-13 | 南京奥康生物技术有限公司 | Detection apparatus for quantitatively sampling samples, and detection method thereof |
| CN205175737U (en) * | 2015-10-27 | 2016-04-20 | 光景生物科技(苏州)有限公司 | Blood sampling external member |
| CN205126255U (en) * | 2015-11-17 | 2016-04-06 | 东台市科华医疗器械有限公司 | High accuracy ration micro blood collection pipette |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107570248A (en) * | 2017-08-28 | 2018-01-12 | 宁夏软件工程院有限公司 | A kind of liquid level sampling pipette |
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| RJ01 | Rejection of invention patent application after publication | ||
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Application publication date: 20161012 |