CN105998870A - Traditional Chinese medicine composition for treating hyperuricemia - Google Patents

Traditional Chinese medicine composition for treating hyperuricemia Download PDF

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Publication number
CN105998870A
CN105998870A CN201610621758.6A CN201610621758A CN105998870A CN 105998870 A CN105998870 A CN 105998870A CN 201610621758 A CN201610621758 A CN 201610621758A CN 105998870 A CN105998870 A CN 105998870A
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herba
chinese medicine
traditional chinese
medicine composition
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赵玉新
王昭霞
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/37—Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538—Schizonepeta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/56—Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/638—Ligustrum, e.g. Chinese privet
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane

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Abstract

The invention relates to the field of a traditional Chinese medicine formula and particularly relates to a traditional Chinese medicine composition for treating hyperuricemia, which is characterized by being prepared from the following raw medicines in parts by weight: 15-20 parts of beautiful sweetgum fruits, 10-15 parts of cogongrass rhizome, 8-12 parts of dayflower, 10-12 parts of honeysuckle stem, 10-15 parts of glossy privet fruits, 6-10 parts of kadsura longipedunculata, 20-25 parts of phellodendron amurense, 6-8 parts of siegesbeckia orientalis, 10-12 parts of folium artemisiae argyi, 12-15 parts of herba schizonepetae, 15-20 parts of taxillus sutchuenensis, 8-10 parts of ash bark, 12-16 parts of heracleum hemsleyanum michaux, 6-10 parts of Chinese holly leaves, 15-20 parts of decumbent corydalis tuber, 16-18 parts of centipeda minima, 12-16 parts of nux vomica, 3-5 parts of patrinia and 3-5 parts of brasenia schreberi. The 19 raw medicines are soaked in water and are decocted, and then dregs are removed to obtain filtrate. The traditional Chinese medicine composition is small in toxic or side effect, low in cost and good in curative effect.

Description

The Chinese medicine composition for the treatment of hyperuricemia
Technical field
The present invention relates to a kind of Chinese patent medicine preparation, a kind of Chinese medicine composition treating hyperuricemia.
Background technology
It is known that hyperuricemia refers under normal purine diet state, non-twice fasting blood uric acid level on the same day Male is higher than 420mmol/L, and women is higher than 360mmol/L.The west of uric acid resisting current to Patients with Hyperuricemia the most clinically Medicine, kind is single, and drug main used to have two classes: 1, promotes the medicine of urate excretion, as benzene smells Ma Long, probenecid etc.；2、 The medicine of suppression uricopoiesis, such as allopurinol.Said medicine is more due to untoward reaction, limits clinical practice.
Summary of the invention
The purpose of the present invention is contemplated to overcome above-mentioned existing technical deficiency, it is provided that a kind of treat in hyperuricemia Drug composition, toxic and side effects is little, with low cost, absorbs fast in digestive tract, and therapeutic effect is good.
The present invention solves above-mentioned technical problem and the technical scheme is that a kind of Chinese medicine composition treating hyperuricemia Thing, is characterized in that being made up of the crude drug of following weight portion, Fructus Liquidambaris 15～20, Rhizoma Imperatae 10～15, Herba Commelinae 8～12, bears Caulis Lonicerae 10～12, Fructus Ligustri Lucidi 10～15, Ramulus et Folium Mussaendae Pubescentis 6～10, Cortex berberidis dasystachyae 20～25, Xian 6～8, Folium Artemisiae Argyi 10～12, Herba Schizonepetae 12～ 15, Herba Taxilli 15～20, Cortex Fraxini 8～10, Radix Angelicae Pubescentis 12～16, Folium Mahoniae 6～10, Rhizoma Corydalis Decumbentis 15～20, Herba Centipedae 16～18, Above-mentioned 19 taste crude drug are soaked in water by Semen Strychni 12～16, Herba Patriniae 3～5, Herba Calthae Membranaceae 3～5, filtrate of removing slag after decocting to obtain.
The invention has the beneficial effects as follows, toxic and side effects is little, with low cost, and therapeutic effect is good.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described:
Embodiment 1:
The every auxiliary medicine of its component (weight portion) is Fructus Liquidambaris 18, Rhizoma Imperatae 13, Herba Commelinae 10, Caulis Lonicerae 11, Fructus Ligustri Lucidi 12, Ramulus et Folium Mussaendae Pubescentis 8, Cortex berberidis dasystachyae 22, Xian 7, Folium Artemisiae Argyi 11, Herba Schizonepetae 13, Herba Taxilli 17, Cortex Fraxini 9, Radix Angelicae Pubescentis 14, Folium Mahoniae 8, Rhizoma Corydalis Decumbentis 17, sandwort Grass 17, Semen Strychni 14, Herba Patriniae 4, Herba Calthae Membranaceae 4.Taking above-mentioned 19 taste crude drug gross weights is 200 grams, and add water 1000ml, soaks 3- 4 hours, boiling slow fire the most with high heat and decoct to about 60 minutes, remove slag to obtain filtrate about 200ml, and it is left that medicinal residues add water 300 The right side, decocts about 30 minutes, and remove slag to obtain filtrate about 100ml, there are about 300ml medicine juice, i.e. prepares decoction of the present invention, loads In sterile glass vials, seal bottle cap is standby.Every day 1 dose point is administered orally for 2 times sooner or later.
Fructus Liquidambaris of the present invention has dispelling, collateral-activating, diuretic, the effect stimulated the menstrual flow；Rhizoma Imperatae cooling blood for hemostasis, clearing away heat and promoting diuresis；Herba Commelinae Row water, heat clearing away, removing heat from blood, removing toxic substances；Caulis Lonicerae has heat-clearing and toxic substances removing, the curative effect of dispelling wind dredging collateral；Fructus Ligustri Lucidi liver and kidney tonifying, improving eyesight, clearly Deficiency-heat；Ramulus et Folium Mussaendae Pubescentis expelling wind and removing dampness, promoting blood circulation and hemostasis, relieving rigidity of muscles and knitting bone, solve poisoning；Cortex berberidis dasystachyae is used for clearing away damp-heat；Relieving heat toxin；Xian has solution Poison, analgesic activity, control systemic pain, quadriplegia；Folium Artemisiae Argyi warming the meridian for stopping bleeding, dispersing cold for relieving pain；Herba Schizonepetae energy town expectorant, dispel the wind, removing heat from blood；Mulberry Parasitism has wind-damp dispelling, liver and kidney tonifying, bone and muscle strengthening, antiabortive effect；Cortex Fraxini heat clearing and damp drying, astringent therapy dysentery relieving, leukorrhagia stopping, improving eyesight；Radix Angelicae Pubescentis is dispelled Wind dehumidifies, arthralgia aggravated by cold pain relieving；Folium Mahoniae has the effectiveness such as clearind deficient heat, liver and kidney tonifying, wind-damp dispelling；Rhizoma Corydalis Decumbentis is invigorated blood circulation active, and circulation of qi promoting is only Bitterly, expelling wind and removing dampness has effect；The effects such as Herba Centipedae has dispersing wind-cold, clearing the nasal passage, cough-relieving, detoxifies, antipruritic；Semen Strychni is excited Stomach invigorating, detumescence poison, removing heat from blood；Herba Patriniae has the effects such as heat-clearing and toxic substances removing, removing blood stasis and expelling pus；Herba Calthae Membranaceae wind dispelling, expelling summer-heat, promoting blood circulation and detumescence.
The each raw material of the present invention also can the embodiment that mixes of ratio (weight portion) listed by according to the form below realize, its processing method with Embodiment one is identical.
Implement Example Lu Lu Logical Herba Imperatae Root The duck sole of the foot Grass Radix Ophiopogonis Rattan Fructus Ligustri Lucidi Son Zijin Rattan Yellow thorn Skin ? Xian Chinese mugwort Leaf Chaste tree Mustard Herba Taxilli Raw The Qin Skin Solely Live Contribution Leaf Summer Nothing Herba Centipedae Semen Strychni Son Herba Patriniae Grass Herba Calthae Membranaceae
Two 15 15 8 12 10 10 20 8 10 15 15 10 12 10 15 18 12 5 3
Three 20 10 12 10 15 6 25 6 12 12 20 8 16 6 20 16 16 3 5
Four 19 12 9 11 12 7 21 7 11 13 18 9 13 7 19 17 13 4 4
The present invention is made further, describes in detail by the clinical trial carried out below in conjunction with my institute:
Clinical data:
From being in hospital and rheumatism immunity special outpatient clinic selection patient with gout 80 example, wherein male 74 example, women 6 example, age 34～55 Year, the course of disease 3 months～4 years.All meet blood uric acid ＞ 420 μm ol/L, and with gouty arthritis and nephropathy.
Therapeutic Method:
Oral, every day 1 dose point is administered orally for 2 times sooner or later, within 10 days, is a course for the treatment of, altogether 6 courses for the treatment of of treatment.
Outcome measure:
1. recovery from illness: clinical symptom disappearance or substantially disappear, blood uric acid is down to normally；The most effective: clinical symptoms is obviously improved, hematuria Acid reduces ＞ 20% earlier above；The most effective: clinical symptoms takes a turn for the better, and blood uric acid reduces ＞ 10%, ＜ 20% earlier above；The most invalid: clinical Increase the weight of even symptom is not improved, without significant change or sb.'s illness took a turn for the worse before blood uric acid and treatment.
Therapeutic outcome:
Fully recover 46 examples, effective 22 examples, effective 8 examples, invalid 4 examples, total effective rate 95%.
Deng, man, 46 years old, pain at left sufficient big toe, pain was more acute, and with redness, impact walking, is after diagnosing Hyperuricemia, uses embodiment one medicament, and every day 1 dose point is administered orally for 2 times sooner or later, within 10 days, is a course for the treatment of.Further consultation after 3 courses for the treatment of, Joint skin rubefaction alleviates, and without obvious tenderness, and after oral Chinese medicine, constipation is substantially alleviated, morning every day is sent to a place under guard greatly Just feeling relaxed time, checks blood uric acid 403umol/L.
Hu, man, 54 years old, there is obvious red and swollen heat pain in joint and surrounding soft tissue, and pain is very violent, during big joint involvement There is joint sepage, with symptoms such as headache, heatings, be diagnosed as gout and hyperuricemia, take the embodiment of the present invention one Chinese medicine Compositions, potion, after serveing on 4 courses for the treatment of, fully recovered, did not recurred every day.

Claims (1)

1. the Chinese medicine composition treating hyperuricemia, it is characterised in that be made up of the crude drug of following weight portion: Lu Lu Logical 15～20, Rhizoma Imperatae 10～15, Herba Commelinae 8～12, Caulis Lonicerae 10～12, Fructus Ligustri Lucidi 10～15, Ramulus et Folium Mussaendae Pubescentis 6～10, yellow thorn Skin 20～25, Xian 6～8, Folium Artemisiae Argyi 10～12, Herba Schizonepetae 12～15, Herba Taxilli 15～20, Cortex Fraxini 8～10, Radix Angelicae Pubescentis 12～16, merit Labor leaf 6～10, Rhizoma Corydalis Decumbentis 15～20, Herba Centipedae 16～18, Semen Strychni 12～16, Herba Patriniae 3～5, Herba Calthae Membranaceae 3～5, by upper State 19 taste crude drug to be soaked in water, filtrate of removing slag after decocting to obtain.
CN201610621758.6A 2016-08-02 2016-08-02 Traditional Chinese medicine composition for treating hyperuricemia Pending CN105998870A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104367899A (en) * 2014-10-20 2015-02-25 安徽省颍上县中医院 Traditional Chinese medicine composition for treating hyperuricemia
CN104547354A (en) * 2015-02-05 2015-04-29 王嘉影 Traditional Chinese medicine for treating hyperuricemia
CN105213906A (en) * 2015-11-06 2016-01-06 江崇礼 A kind of Chinese medicine composition being used for the treatment of gout and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104367899A (en) * 2014-10-20 2015-02-25 安徽省颍上县中医院 Traditional Chinese medicine composition for treating hyperuricemia
CN104547354A (en) * 2015-02-05 2015-04-29 王嘉影 Traditional Chinese medicine for treating hyperuricemia
CN105213906A (en) * 2015-11-06 2016-01-06 江崇礼 A kind of Chinese medicine composition being used for the treatment of gout and preparation method thereof

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