CN105963705A - Compound stabilizer for preserving gingerol and use method of compound stabilizer - Google Patents
Compound stabilizer for preserving gingerol and use method of compound stabilizer Download PDFInfo
- Publication number
- CN105963705A CN105963705A CN201610413151.9A CN201610413151A CN105963705A CN 105963705 A CN105963705 A CN 105963705A CN 201610413151 A CN201610413151 A CN 201610413151A CN 105963705 A CN105963705 A CN 105963705A
- Authority
- CN
- China
- Prior art keywords
- gingerol
- preserving
- compound stabilizer
- complex stabilizer
- temperature
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- JZLXEKNVCWMYHI-UHFFFAOYSA-N gingerol Natural products CCCCC(O)CC(=O)CCC1=CC=C(O)C(OC)=C1 JZLXEKNVCWMYHI-UHFFFAOYSA-N 0.000 title claims abstract description 49
- NLDDIKRKFXEWBK-AWEZNQCLSA-N gingerol Chemical compound CCCCC[C@H](O)CC(=O)CCC1=CC=C(O)C(OC)=C1 NLDDIKRKFXEWBK-AWEZNQCLSA-N 0.000 title claims abstract description 48
- 235000002780 gingerol Nutrition 0.000 title claims abstract description 48
- 239000003381 stabilizer Substances 0.000 title claims abstract description 35
- 238000000034 method Methods 0.000 title claims abstract description 23
- 150000001875 compounds Chemical class 0.000 title abstract description 10
- 229910017053 inorganic salt Inorganic materials 0.000 claims abstract description 16
- 229920001353 Dextrin Polymers 0.000 claims abstract description 11
- 239000004375 Dextrin Substances 0.000 claims abstract description 11
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 11
- 235000019425 dextrin Nutrition 0.000 claims abstract description 11
- 239000008103 glucose Substances 0.000 claims abstract description 11
- 238000003756 stirring Methods 0.000 claims abstract description 10
- 235000012424 soybean oil Nutrition 0.000 claims abstract description 6
- 239000003549 soybean oil Substances 0.000 claims abstract description 6
- 239000002994 raw material Substances 0.000 claims abstract description 4
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims description 6
- 235000010469 Glycine max Nutrition 0.000 claims description 5
- 244000068988 Glycine max Species 0.000 claims description 5
- 238000009413 insulation Methods 0.000 claims description 5
- 230000014759 maintenance of location Effects 0.000 claims description 5
- 239000003921 oil Substances 0.000 claims description 5
- 235000019198 oils Nutrition 0.000 claims description 5
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 4
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 claims description 4
- 229910021380 Manganese Chloride Inorganic materials 0.000 claims description 3
- GLFNIEUTAYBVOC-UHFFFAOYSA-L Manganese chloride Chemical compound Cl[Mn]Cl GLFNIEUTAYBVOC-UHFFFAOYSA-L 0.000 claims description 3
- 229960002089 ferrous chloride Drugs 0.000 claims description 3
- NMCUIPGRVMDVDB-UHFFFAOYSA-L iron dichloride Chemical compound Cl[Fe]Cl NMCUIPGRVMDVDB-UHFFFAOYSA-L 0.000 claims description 3
- 235000002867 manganese chloride Nutrition 0.000 claims description 3
- 239000011565 manganese chloride Substances 0.000 claims description 3
- 229940099607 manganese chloride Drugs 0.000 claims description 3
- 239000001103 potassium chloride Substances 0.000 claims description 3
- 235000011164 potassium chloride Nutrition 0.000 claims description 3
- GVPFVAHMJGGAJG-UHFFFAOYSA-L cobalt dichloride Chemical compound [Cl-].[Cl-].[Co+2] GVPFVAHMJGGAJG-UHFFFAOYSA-L 0.000 claims description 2
- 229940097267 cobaltous chloride Drugs 0.000 claims description 2
- 229960002816 potassium chloride Drugs 0.000 claims description 2
- 239000011780 sodium chloride Substances 0.000 claims description 2
- 229960002668 sodium chloride Drugs 0.000 claims description 2
- 235000005074 zinc chloride Nutrition 0.000 claims description 2
- 239000011592 zinc chloride Substances 0.000 claims description 2
- 229960001939 zinc chloride Drugs 0.000 claims description 2
- 239000011833 salt mixture Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 7
- 230000003111 delayed effect Effects 0.000 abstract 1
- 238000004321 preservation Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 description 5
- 125000003118 aryl group Chemical group 0.000 description 4
- 235000013305 food Nutrition 0.000 description 3
- IMNFDUFMRHMDMM-UHFFFAOYSA-N N-Heptane Chemical compound CCCCCCC IMNFDUFMRHMDMM-UHFFFAOYSA-N 0.000 description 2
- 230000003064 anti-oxidating effect Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 2
- 235000013824 polyphenols Nutrition 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- AIULWNKTYPZYAN-SFHVURJKSA-N (10)-Gingerol Chemical compound CCCCCCCCC[C@H](O)CC(=O)CCC1=CC=C(O)C(OC)=C1 AIULWNKTYPZYAN-SFHVURJKSA-N 0.000 description 1
- CTGAPJBPSCUFRO-HNNXBMFYSA-N (5s)-1-(3,4-dimethoxyphenyl)-5-hydroxydecan-3-one Chemical compound CCCCC[C@H](O)CC(=O)CCC1=CC=C(OC)C(OC)=C1 CTGAPJBPSCUFRO-HNNXBMFYSA-N 0.000 description 1
- OQWKEEOHDMUXEO-UHFFFAOYSA-N (6)-shogaol Natural products CCCCCC=CC(=O)CCC1=CC=C(O)C(OC)=C1 OQWKEEOHDMUXEO-UHFFFAOYSA-N 0.000 description 1
- BCIWKKMTBRYQJU-INIZCTEOSA-N (8)-Gingerol Chemical compound CCCCCCC[C@H](O)CC(=O)CCC1=CC=C(O)C(OC)=C1 BCIWKKMTBRYQJU-INIZCTEOSA-N 0.000 description 1
- ZEASWHWETFMWCV-UHFFFAOYSA-N 7-O-(2-O-Acetyl-6-O-Methyl-beta-D-glucuronoside)-4',5,7-Trihydroxyflavone Natural products C=1C(O)=C(O)C2=C(O)C(=O)C=C(C3C(CC4=C(O)C=C(O)C=C4O3)OC(=O)C=3C=C(O)C(O)=C(O)C=3)C=C2C=1C1OC2=CC(O)=CC(O)=C2CC1OC(=O)C1=CC(O)=C(O)C(O)=C1 ZEASWHWETFMWCV-UHFFFAOYSA-N 0.000 description 1
- VSDUZFOSJDMAFZ-UHFFFAOYSA-N 8-gingerol Natural products COC(=O)C(N)CC1=CC=CC=C1 VSDUZFOSJDMAFZ-UHFFFAOYSA-N 0.000 description 1
- AIULWNKTYPZYAN-UHFFFAOYSA-N 810gingerol Natural products CCCCCCCCCC(O)CC(=O)CCC1=CC=C(O)C(OC)=C1 AIULWNKTYPZYAN-UHFFFAOYSA-N 0.000 description 1
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- -1 Hydroxyl Chemical group 0.000 description 1
- CTGAPJBPSCUFRO-UHFFFAOYSA-N Methylgingerol Natural products CCCCCC(O)CC(=O)CCC1=CC=C(OC)C(OC)=C1 CTGAPJBPSCUFRO-UHFFFAOYSA-N 0.000 description 1
- OQWKEEOHDMUXEO-BQYQJAHWSA-N [6]-Shogaol Chemical compound CCCCC\C=C\C(=O)CCC1=CC=C(O)C(OC)=C1 OQWKEEOHDMUXEO-BQYQJAHWSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000000954 anitussive effect Effects 0.000 description 1
- 230000003474 anti-emetic effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 239000002111 antiemetic agent Substances 0.000 description 1
- 229940124584 antitussives Drugs 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000002279 cholagogic effect Effects 0.000 description 1
- 239000008139 complexing agent Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- PCHPORCSPXIHLZ-UHFFFAOYSA-N diphenhydramine hydrochloride Chemical compound [Cl-].C=1C=CC=CC=1C(OCC[NH+](C)C)C1=CC=CC=C1 PCHPORCSPXIHLZ-UHFFFAOYSA-N 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000001156 gastric mucosa Anatomy 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 150000003333 secondary alcohols Chemical class 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses a compound stabilizer for preserving gingerol and a use method of the compound stabilizer, and by means of the compound stabilizer, activity of gingerol can be preserved for a long time. The compound stabilizer is prepared by mixing and stirring, by weight, 100-200 parts of soybean oil, 1-3 parts of white dextrin, 5-10 parts of glucose and 1-3 parts of inorganic salt. The use method includes the steps that the compound stabilizer and the gingerol are heated to a certain temperature and then mixed to be uniform rapidly, stirring is conducted while the raw materials are added, then heat preservation is conducted at a proper temperature, and the compound stabilizer is prepared. By means of the compound stabilizer, the gingerol can maintain stable in a solution, and recession of activity is delayed. Raw materials are easy to obtain, and gingerol activity can be maintained within one year at the temperature of 4 DEG C.
Description
Technical field
The invention belongs to biological technical field.It is specifically related to a kind of complex stabilizer preserving gingerol and using method thereof.
Background technology
Gingerol includes single aromatic ring and double aromatic ring protective embankment in heptan two class.Single aromatic ring class gingerol includes again 1. 6-gingerol, 2. 8-gingerol, 3. 10-gingerol, the 4. composition such as 12-gingerol, methyl-6-gingerol, double aromatic ring protective embankment in heptan class gingerols also include many compositions, it is different that its architectural difference is mainly aromatic ring substituents, and this construction features makes the chemical property extremely unstable of gingerol.Such as, in acid condition, C4Active hydrogen easily with C5Hydroxyl be dehydrated formation shogaol together.The biological activity of gingerol is also affected by factors such as side chain length.Phenolic hydroxyl group is the architecture basics that gingerol has antioxidation.Phenolic hydroxyl group in gingerol molecule, carbonyl, hydroxy functional group make gingerol have general phenols, ketone, the general character of secondary alcohols material, it is possible to the general chemical reaction of these compounds occurs.Gingerol have anticoagulant, antioxidation, antitumor, boosting heart tonifying, blood fat reducing, atherosclerosis, protection gastric mucosa, hepatic cholagogic, antiinflammatory, antitussive, Anti-dizzy anti-emetic, to multiple efficacies such as central nerve inhibition.Therefore in pharmaceutical industry and food service industry, there is purposes widely.
But the stability of gingerol is always a well-known difficult problem, particularly in the middle of the food containing gingerol and medicine, it is ensured that the change the most in time of the activity of gingerol and to change be a hang-up.
Therefore, in order to improve the stability of gingerol, it is necessary to develop a kind of novel stabilizer.
Summary of the invention
It is an object of the invention to provide a kind of complex stabilizer preserving gingerol and using method thereof, the activity of gingerol can be kept the long period.
The purpose of the present invention is achieved through the following technical solutions:
The present invention is a kind of complex stabilizer preserving gingerol and using method thereof, raw soybeans oil, white dextrin, glucose, inorganic salt stir formulated；Its using method is: complex stabilizer and gingerol are heated to certain temperature, then both are mixed rapidly, stir while adding, then the insulation regular hour at a suitable temperature.
Described inorganic salt is one or more in manganese chloride, ferrous chloride, zinc chloride, cobaltous chloride, sodium chloride and potassium chloride.
Described each material content is: soybean oil 100-200 part, white dextrin 1-3 part, glucose 5-10 part, inorganic salt 1-3 part.
Described heating-up temperature is 30 DEG C-40 DEG C, and holding temperature is 25 DEG C-35 DEG C.
Described temperature retention time is 50-70min.
Described gingerol is 3:10 with the weight ratio of complex stabilizer.
Using method as preferred gingerol complexing agent is: complex stabilizer and gingerol are heated to 35 DEG C, then both is mixed rapidly, stirs while adding, then is incubated 60min at 30 DEG C.
Compared with prior art, the method have the advantages that
(1) product of the present invention can make gingerol activity decay slow down, and can stablize gingerol activity in solution and reach more than 12 months；
(2) present component is simple, and raw material is natural, with low cost, and preparation method is easy, there is not the harm to human body, can expand gingerol range of application in food and medicine trade.
Detailed description of the invention
Embodiment 1
A kind of complex stabilizer preserving gingerol and using method thereof, stirred formulated by raw soybeans oil, white dextrin, glucose, inorganic salt；Its using method is: complex stabilizer and gingerol are heated to certain temperature, then both are mixed rapidly, stir while adding, then the insulation regular hour at a suitable temperature.
Described inorganic salt is manganese chloride.
Described each material content is: soybean oil 100g, white dextrin 1g, glucose 5g, inorganic salt 1g.
Described heating-up temperature is 30 DEG C, and holding temperature is 25 DEG C.
Described temperature retention time is 50min.
Described gingerol is 3:10 with the weight ratio of complex stabilizer.
Embodiment 2
A kind of complex stabilizer preserving gingerol and using method thereof, stirred formulated by raw soybeans oil, white dextrin, glucose, inorganic salt；Its using method is: complex stabilizer and gingerol are heated to certain temperature, then both are mixed rapidly, stir while adding, then the insulation regular hour at a suitable temperature.
Described inorganic salt is ferrous chloride.
Described each material content is: soybean oil 150g, white dextrin 2g, glucose 8g, inorganic salt 2g.
Described heating-up temperature is 35 DEG C, and holding temperature is 30 DEG C.
Described temperature retention time is 60min.
Described gingerol is 3:10 with the weight ratio of complex stabilizer.
Embodiment 3
A kind of complex stabilizer preserving gingerol and using method thereof, stirred formulated by raw soybeans oil, white dextrin, glucose, inorganic salt；Its using method is: complex stabilizer and gingerol are heated to certain temperature, then both are mixed rapidly, stir while adding, then the insulation regular hour at a suitable temperature.
Described inorganic salt is potassium chloride.
Described each material content is: soybean oil 200g, white dextrin 3g, glucose 10g, inorganic salt 3g.
Described heating-up temperature is 40 DEG C, and holding temperature is 35 DEG C.
Described temperature retention time is 70min.
Described gingerol is 3:10 with the weight ratio of complex stabilizer.
Claims (6)
1. the complex stabilizer preserving gingerol and using method thereof, it is characterised in that: complex stabilizer is made up of the stirring of raw soybeans oil, white dextrin, glucose and inorganic salt mixture；Its using method is: complex stabilizer and gingerol are heated to certain temperature, then both are mixed rapidly, stir while adding, then the insulation regular hour at a suitable temperature.
2. a kind of complex stabilizer preserving gingerol described in claim 1 and using method thereof, it is characterised in that: each parts by weight of raw materials is: soybean oil 100-200 part, white dextrin 1-3 part, glucose 5-10 part, inorganic salt 1-3 part.
3. a kind of complex stabilizer preserving gingerol described in any one of claim 1 or 2 and using method thereof, it is characterised in that: described inorganic salt is one or more in manganese chloride, ferrous chloride, zinc chloride, cobaltous chloride, sodium chloride and potassium chloride.
4. a kind of complex stabilizer preserving gingerol described in claim 1 and using method thereof, it is characterised in that: heating-up temperature is 30 DEG C-40 DEG C, and holding temperature is 25 DEG C-35 DEG C.
5. a kind of complex stabilizer preserving gingerol described in claim 1 and using method thereof, it is characterised in that: temperature retention time is 50-70min.
6. a kind of complex stabilizer preserving gingerol described in claim 1 and using method thereof, it is characterised in that: gingerol is 3:10 with the weight ratio of complex stabilizer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610413151.9A CN105963705A (en) | 2016-06-13 | 2016-06-13 | Compound stabilizer for preserving gingerol and use method of compound stabilizer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610413151.9A CN105963705A (en) | 2016-06-13 | 2016-06-13 | Compound stabilizer for preserving gingerol and use method of compound stabilizer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105963705A true CN105963705A (en) | 2016-09-28 |
Family
ID=57010412
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610413151.9A Pending CN105963705A (en) | 2016-06-13 | 2016-06-13 | Compound stabilizer for preserving gingerol and use method of compound stabilizer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105963705A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106954840A (en) * | 2017-03-27 | 2017-07-18 | 湖北文理学院 | A kind of gingerol compound stabilizer containing Rhizoma Gastrodiae extract |
| CN106963789A (en) * | 2017-03-27 | 2017-07-21 | 湖北文理学院 | A kind of gingerol compound stabilizer containing Cordyceps extract |
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2016
- 2016-06-13 CN CN201610413151.9A patent/CN105963705A/en active Pending
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| CN104447260A (en) * | 2014-11-20 | 2015-03-25 | 广东产品质量监督检验研究院 | Method of producing gingerol by gingerol oxime |
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| 刘正实等: "姜酚类化合物的稳定性及其抗氧化性能研究", 《重庆工商大学学报(自然科学版)》 * |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106954840A (en) * | 2017-03-27 | 2017-07-18 | 湖北文理学院 | A kind of gingerol compound stabilizer containing Rhizoma Gastrodiae extract |
| CN106963789A (en) * | 2017-03-27 | 2017-07-21 | 湖北文理学院 | A kind of gingerol compound stabilizer containing Cordyceps extract |
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