CN105963002A - Three-dimensional printed minimally invasive guide template and making method thereof - Google Patents
Three-dimensional printed minimally invasive guide template and making method thereof Download PDFInfo
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- CN105963002A CN105963002A CN201610620011.9A CN201610620011A CN105963002A CN 105963002 A CN105963002 A CN 105963002A CN 201610620011 A CN201610620011 A CN 201610620011A CN 105963002 A CN105963002 A CN 105963002A
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- die plate
- inserting needle
- wicresoft
- guiding die
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3403—Needle locating or guiding means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3468—Trocars; Puncturing needles for implanting or removing devices, e.g. prostheses, implants, seeds, wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1007—Arrangements or means for the introduction of sources into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3403—Needle locating or guiding means
- A61B2017/3405—Needle locating or guiding means using mechanical guide means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3403—Needle locating or guiding means
- A61B2017/3405—Needle locating or guiding means using mechanical guide means
- A61B2017/3407—Needle locating or guiding means using mechanical guide means including a base for support on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3403—Needle locating or guiding means
- A61B2017/3405—Needle locating or guiding means using mechanical guide means
- A61B2017/3411—Needle locating or guiding means using mechanical guide means with a plurality of holes, e.g. holes in matrix arrangement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1007—Arrangements or means for the introduction of sources into the body
- A61N2005/1012—Templates or grids for guiding the introduction of sources
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Apparatus For Radiation Diagnosis (AREA)
Abstract
The invention provides a three-dimensional printed minimally invasive guide template and a making method thereof. The making method comprises the steps that scanning is conducted on a target part to obtain a three-dimensional image of the target part; reconstruction is conducted according to the obtained three-dimensional image, and a three-dimensional model of the target part is obtained; needle insertion directions, needle insertion positions and needle insertion depths are planned according to the reconstructed three-dimensional model and requirements of doctors, and dosage is conformally distributed on source particle positions; a guide template digital model is built according to the reconstructed three-dimensional model and the planned needle insertion directions, needle insertion positions and needle insertion depths; the guide template digital model is printed into the three-dimensional printed minimally invasive guide template by means of a 3D printing technology. According to the three-dimensional printed minimally invasive guide template and the making method thereof, the reliability and effect of implanting treatment can be improved, operation labor intensity is reduced, the operation time is shortened, and a risk is reduced.
Description
Technical field
The present invention relates to the technical field of minimally invasive medical, more specifically, relate to a kind of 3D and print
Wicresoft's guiding die plate and manufacture method thereof.
Background technology
Radiotherapy (radiotherapy) is one of critical treatment method for tumor.For maximum limit
Degree ground reduces radiotherapy side effect and the damage of radiotherapy normal tissue, develops radioactive particle
Implanted treatment technology (hereinafter referred to as seeds implanted).
Seeds implanted is a kind of by inside radioactive source implantation tumour, allows it with the treatment of destroyed tumor
Means.Seeds implanted treatment technology relates to radioactive source, and its core is radion.Seeds implanted
Rely primarily on orientation system by radioactive prospecting instrument tumor body, sent by mini-radioactive resource and hold
Continuous, short-range lonizing radiation, make tumor tissues be killed to greatest extent, and normal structure are not
Damage or only microlesion.
Current seeds implanted operation is typically to be carried out by rule of thumb by doctor clinically, and this is just to doctor
Raw Couple herbs and skill propose the highest requirement.Traditional is carried out under CT is image-guided
Inner irradiation operation, due to exist several so that tens, up to a hundred points of puncture, in art substantially
It is " blind wear ".It addition, the tumor seeds implanted planning system that currently oneself has is all based on one-dimensional
Or bidimensional image data carry out pre-planned to puncturing inserting needle passage, can not calculate the place of particle
Prescription amount, after this just often results in seeds implanted, there is " hot-zone " (dosage mistake in inside tumor
Cause greatly side effect) and/or the adverse consequences of " cold-zone " (dosage is too small to be caused to no effect).
The information being disclosed in this background section is merely intended to deepen the general background to the present invention
The understanding of technology, and be not construed as recognizing or implying this information structure in any form
Prior art known to those skilled in the art.
Summary of the invention
The present invention is directed to existing tumor planning software, system and Traditional Man and puncture the defect implanted,
According to doctor's requirement to dosage, dosiology algorithm is used to obtain preferred particle cloth source scheme, and
Planning inserting needle passage on this basis.Ensureing that radiological dose can effective killing tumor cell
Adequately protect health tissues simultaneously, significantly reduces radiocurable side effect.The present invention is three
On dimension word model, inserting needle passage is planned, it is possible to evade overwhelming majority normal structure organ
(skeleton, blood vessel, nerve etc.), are aided with the conformal template of 3D printing and carry out surgical navigational,
While improve operation safety, also greatly reduce the labor intensity of doctor, improve hands
Art success rate and therapeutic effect.
The application provides a kind of 3D to print the manufacture method of Wicresoft's guiding die plate, it is characterised in that
Described manufacture method comprises the following steps: scanning step, is scanned target site obtaining institute
State the 3-D view of target site;Reconstruction step, the described 3-D view reconstruct according to obtaining obtains
Obtain the threedimensional model of described target site;Planning step, according to threedimensional model and the doctor of reconstruct
Raw requirement plans inserting needle direction, inserting needle position and depth of needle, dosage conformal cloth source particles position
Put;Modeling procedure, according to threedimensional model and the inserting needle direction of planning of reconstruct, inserting needle position with
And depth of needle, set up guiding die plate mathematical model;Printing step, will by 3D printing technique
The printing of described guiding die plate mathematical model becomes 3D and prints Wicresoft's guiding die plate, wherein, described heavy
Structure step, described planning step and described modeling procedure utilize treatment planning systems to carry out;
In described planning step, the planning of inserting needle direction, inserting needle position and depth of needle be based on
The three-dimensional position of normal structure organ is carried out;In described printing step, it is thus achieved that 3D print
Wicresoft's guiding die plate is fitted with described target site adaptability.
Preferably, plan inserting needle direction, inserting needle position and depth of needle at described planning step,
Dosage conformal cloth source particles position, multiple inserting needle directions that planning obtains.
Preferably, in described planning step, plan that multiple inserting needle direction is with many in three dimensions
Individual inserting needle position.
Preferably, multiple inserting needle directions can according to rebuild image data freely evade one or
Multiple histoorgans.
Preferably, dosage conformal cloth source particles position, Rapid Dose Calculation is that full 3-dimensional calculates in real time.
The application also provides for a kind of 3D and prints Wicresoft's guiding die plate, and described 3D prints Wicresoft and guides
Template is that above-described 3D prints the manufacture method of Wicresoft's guiding die plate and obtains.From another
Individual angle is said, be threedimensional model and the inserting needle direction of planning according to reconstruct, inserting needle position and
Depth of needle, sets up guiding die plate mathematical model, uses 3D to print the manufacture of Wicresoft's guiding die plate
Method and obtain.
The 3D of the present invention prints Wicresoft's guiding die plate and is particularly suitable for tumor seeds implanted, utilizes art
The patient image of front acquisition learns data (CT etc.) and sets up three-dimensional three-dimensional digit model, for doctor
Radiological dose required for life, by algorithmic rule particle cloth source position, and safely and effectively
Plan inserting needle passage under dosage premise, and generation is led for assisting the 3D puncturing inserting needle to print Wicresoft
To template.Based on mathematical model, print Wicresoft guiding die plate for auxiliary implementation with 3D,
Ensure that safety and puncture needle site, depth of needle, the essence of particle distribution of radiological dose
Really property, evades out human body vital tissue simultaneously, decreases doctor and depend on image information in art
Rely, reduce labor intensity and difficulty, also for medical reform " classification diagnosis and treatment " at oncotherapy
The popularization in field provides objective base.
The 3D of the present invention prints Wicresoft's guiding die plate and is also suitable for applying at argon helium knife ablative surgery
With frost ablative surgery on.Such as, utilize the present invention can carry out seeds implanted to combine frost and disappear
Melt operation, print needle track and the frost printing applicable seeds implanted on Wicresoft's guiding die plate at 3D
The needle track of ablation needle, had not only implanted particle but also had carried out frost in once operation and melted.
By accompanying drawing and detailed description of the invention subsequently, the further feature that the present invention is had and
Advantage will become clearer from.
Accompanying drawing explanation
Fig. 1 is the stream that 3D according to embodiments of the present invention prints the manufacture method of Wicresoft's guiding die plate
Cheng Tu.
Fig. 2 is the schematic diagram that 3D according to embodiments of the present invention prints Wicresoft's guiding die plate.
Fig. 3 is that 3D according to embodiments of the present invention prints Wicresoft's guiding die plate Conducted Puncture signal
Figure.
Detailed description of the invention
Reference will be made in detail now each embodiment of the present invention, the example of these embodiments
It is shown in the accompanying drawings and is described as follows.Although the present invention will combine with exemplary
It is described, it will be appreciated that this specification is not intended to limit the invention to those
Exemplary.On the contrary, it is contemplated that not only cover these exemplary,
And cover and can be included in the spirit and scope of the present invention being defined by the appended claims
Within various selection forms, modification, equivalents and other embodiment.
Fig. 1 is the stream that 3D according to embodiments of the present invention prints the manufacture method of Wicresoft's guiding die plate
Cheng Tu.
3D according to embodiments of the present invention prints the manufacture method of Wicresoft's guiding die plate and includes scanning
Step S101, reconstruction step S102, planning step S103, modeling procedure S104 and printing step
Rapid S105.
Scanning step S101 includes the 3-D view that target site is scanned obtain target site.
This scanning is to use CT scan (CT) equipment or NMR (Nuclear Magnetic Resonance)-imaging (MRI)
Equipment is carried out, and target site is lesions position and focus peripheral part, such as include buttocks,
Chest, head, cervical region, back, waist, extremity portion or other positions of health.
Reconstruction step S102 includes the three-dimensional obtaining target site according to the 3-D view reconstruct obtained
Model.According to the technical characteristic scanned before, reconstruct here can also be to obtain based on scanning
Multiple tomographs carry out.
Planning step S103 includes that the threedimensional model according to reconstruct and doctor require to plan inserting needle side
To, inserting needle position and depth of needle, dosage conformal cloth source particles position.
Modeling procedure S104 includes the threedimensional model according to reconstruct and the inserting needle direction of planning, inserting needle
Position and depth of needle, set up guiding die plate mathematical model.
Printing step S105 includes that being directed to template mathematical model by 3D printing technique is printed as
Wicresoft's guiding die plate is printed for 3D.
Reconstruction step S102, planning step S103 and modeling procedure S104 are to utilize treatment plan
System (TPS) is carried out.
In planning step S103, the planning of inserting needle direction, inserting needle position and depth of needle is
Three-dimensional position based on normal structure organ is carried out.
In printing step S105, it is thus achieved that 3D print Wicresoft guiding die plate and fit with target site
Answering property is fitted.3-D view owing to obtaining in scanning step before has comprised mesh
The shape and size information at mark position, and these information in follow-up reconstruct, model, print step
Having got back in Zhou and transmitted and retain, therefore, the final 3D obtained prints Wicresoft's guiding die plate energy
Enough adaptability laminating target sites, thus effectively reduce inserting needle direction, inserting needle position and inserting needle
There is the probability of error in the degree of depth, reduces the harmful effect to therapeutic effect.
According to a preferred embodiment of the invention, planning step is planned inserting needle direction, inserting needle position
Put and depth of needle, dosage conformal cloth source particles position, multiple inserting needle directions that planning obtains.
In planning step, plan multiple inserting needle direction and multiple inserting needle position in three dimensions.Multiple
One or more histoorgan can freely be evaded according to the image data rebuild in inserting needle direction.Agent
Measuring conformal cloth source particles position, Rapid Dose Calculation is that full 3-dimensional calculates in real time.
According to a preferred embodiment of the invention, planning step S103 plans multiple particle cloth source
Position, and accordingly based upon each particle cloth source position planning inserting needle direction, inserting needle position with
And depth of needle, multiple inserting needle directions that planning obtains are parallel to each other.Inserting needle side parallel to each other
Print and inserting needle behavior to follow-up 3D can be simplified.
According to another preferred embodiment of the invention, in planning step S103, in three dimensions
Plan multiple inserting needle direction and multiple inserting needle position.It is to say, be required to adopt according to the state of an illness
By different inserting needle forms, such as can be to use multiple inserting needle directions form parallel to each other, also
Can its objective is so that inserting needle passage avoids normal structure or organ to use uneven form,
Such as prevent inserting needle passage from passing from osseous tissue, thus reduce operation risk, simplify hands
Art process.
Fig. 2 is the schematic diagram that 3D according to embodiments of the present invention prints Wicresoft's guiding die plate.According to
Template shown in Fig. 2, be provided with laminating patient's CT scan time fixed position anchor point 21 with
And CT lower bolster positions line 22, so holding very much with the cross of laser positioning during patient body reset
Easily template is resetted.In other words, the locating point position of labelling when anchor point 21 and patient are CT
Identical, location line 22 overlaps with CT laser positioning line.The three-dimensional needle track 23 that punctures is to pass through TPS
Calculate and design.In seeds implanted treatment operation, particle under corresponding needle track and each needle track
Quantity and position are described in prospectus, meet the requirement of seeds implanted treatment.
Fig. 3 is that 3D according to embodiments of the present invention prints Wicresoft's guiding die plate Conducted Puncture signal
Figure.In Fig. 3,3D prints the conformal template of Wicresoft 33 and body surface is fitted after fixing, and performs the operation,
Owing to taking three-dimensional inserting needle to devise puncture needle track 32, so the piercing process of puncture needle 31 is avoided
Blood vessel 34 and skeleton 35 and other normal structure organs, the most accurately arrive in tumor 36
Appropriate location, decrease operating time, reduce patient ailing.
Compared with prior art, the present invention can deposit in technological layer solves seeds implanted operation
Inserting needle passage and the problem such as cloth source position is inaccurate, radiological dose is unreasonable;Can be from mark
The angle of standardization improves reliability and the curative effect of seeds implanted treatment;Doctor institute can be reduced simultaneously
The muscle power that undertakes, energy intensity, greatly reduce operating time and risk, make more doctor permissible
Seeds implanted iatrotechnics is implemented in the case of safety is to be fully ensured.
The description that above embodiment specific illustrative to the present invention is presented is in order at explanation and retouches
The purpose stated.Description above is not intended to become milli exhaustively, is not intended to this
Bright it is limited to disclosed precise forms, it is clear that according to above-mentioned teaching, a lot of changes and change
It is all possible.The scope of the present invention is intended to be limited by appended claims and equivalents.
Claims (6)
1. a 3D prints the manufacture method of Wicresoft's guiding die plate, it is characterised in that described system
The method of making comprises the following steps:
Scanning step, is scanned obtaining the 3-D view of described target site to target site;
Reconstruction step, the described 3-D view reconstruct according to obtaining obtains the three of described target site
Dimension module;
Planning step, threedimensional model and doctor according to reconstruct require to plan inserting needle direction, enter
Pin position and depth of needle, dosage conformal cloth source particles position;
Modeling procedure, according to threedimensional model and the inserting needle direction of planning of reconstruct, inserting needle position with
And depth of needle, set up guiding die plate mathematical model;
Printing step, is become the printing of described guiding die plate mathematical model by 3D printing technique
3D prints Wicresoft's guiding die plate,
Wherein, described reconstruction step, described planning step and described modeling procedure are to utilize treatment
Planning system is carried out;
In described planning step, the planning of inserting needle direction, inserting needle position and depth of needle is
Three-dimensional position based on normal structure organ is carried out;
In described printing step, it is thus achieved that 3D print Wicresoft guiding die plate and described target site
Adaptability is fitted.
3D the most according to claim 1 prints the manufacture method of Wicresoft's guiding die plate, its
It is characterised by, described planning step is planned inserting needle direction, inserting needle position and depth of needle,
Dosage conformal cloth source particles position, multiple inserting needle directions that planning obtains.
3D the most according to claim 1 prints the manufacture method of Wicresoft's guiding die plate, its
It is characterised by, in described planning step, plans multiple inserting needle direction and multiple in three dimensions
Inserting needle position.
3D the most according to claim 3 prints the manufacture method of Wicresoft's guiding die plate, its
Being characterised by, multiple inserting needle directions can freely evade one or many according to the image data rebuild
Individual histoorgan.
3D the most according to claim 1 prints the manufacture method of Wicresoft's guiding die plate, its
Being characterised by, dosage conformal cloth source particles position, Rapid Dose Calculation is that full 3-dimensional calculates in real time.
6. a 3D prints Wicresoft's guiding die plate, it is characterised in that according to the three-dimensional mould of reconstruct
Type and the inserting needle direction of planning, inserting needle position and depth of needle, set up guiding die plate numeral mould
Type, uses 3D to print the manufacture method of Wicresoft's guiding die plate and obtain.
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CN106362309A (en) * | 2016-09-29 | 2017-02-01 | 陕西东望科贸有限公司 | Method for customizing tumor radiotherapy baffle |
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CN106362309A (en) * | 2016-09-29 | 2017-02-01 | 陕西东望科贸有限公司 | Method for customizing tumor radiotherapy baffle |
CN106362309B (en) * | 2016-09-29 | 2019-03-22 | 陕西东望科技有限公司 | A method of customization tumour radiotherapy baffle |
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