CN105963002A - Three-dimensional printed minimally invasive guide template and making method thereof - Google Patents

Three-dimensional printed minimally invasive guide template and making method thereof Download PDF

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Publication number
CN105963002A
CN105963002A CN201610620011.9A CN201610620011A CN105963002A CN 105963002 A CN105963002 A CN 105963002A CN 201610620011 A CN201610620011 A CN 201610620011A CN 105963002 A CN105963002 A CN 105963002A
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CN
China
Prior art keywords
die plate
inserting needle
wicresoft
guiding die
planning
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Pending
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CN201610620011.9A
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Chinese (zh)
Inventor
李硕
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Beijing Kai Lin Technology Co Ltd
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Beijing Kai Lin Technology Co Ltd
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Priority to CN201610620011.9A priority Critical patent/CN105963002A/en
Publication of CN105963002A publication Critical patent/CN105963002A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3403Needle locating or guiding means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3468Trocars; Puncturing needles for implanting or removing devices, e.g. prostheses, implants, seeds, wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007Arrangements or means for the introduction of sources into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3403Needle locating or guiding means
    • A61B2017/3405Needle locating or guiding means using mechanical guide means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3403Needle locating or guiding means
    • A61B2017/3405Needle locating or guiding means using mechanical guide means
    • A61B2017/3407Needle locating or guiding means using mechanical guide means including a base for support on the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3403Needle locating or guiding means
    • A61B2017/3405Needle locating or guiding means using mechanical guide means
    • A61B2017/3411Needle locating or guiding means using mechanical guide means with a plurality of holes, e.g. holes in matrix arrangement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007Arrangements or means for the introduction of sources into the body
    • A61N2005/1012Templates or grids for guiding the introduction of sources

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Apparatus For Radiation Diagnosis (AREA)

Abstract

The invention provides a three-dimensional printed minimally invasive guide template and a making method thereof. The making method comprises the steps that scanning is conducted on a target part to obtain a three-dimensional image of the target part; reconstruction is conducted according to the obtained three-dimensional image, and a three-dimensional model of the target part is obtained; needle insertion directions, needle insertion positions and needle insertion depths are planned according to the reconstructed three-dimensional model and requirements of doctors, and dosage is conformally distributed on source particle positions; a guide template digital model is built according to the reconstructed three-dimensional model and the planned needle insertion directions, needle insertion positions and needle insertion depths; the guide template digital model is printed into the three-dimensional printed minimally invasive guide template by means of a 3D printing technology. According to the three-dimensional printed minimally invasive guide template and the making method thereof, the reliability and effect of implanting treatment can be improved, operation labor intensity is reduced, the operation time is shortened, and a risk is reduced.

Description

3D prints Wicresoft's guiding die plate and manufacture method thereof
Technical field
The present invention relates to the technical field of minimally invasive medical, more specifically, relate to a kind of 3D and print Wicresoft's guiding die plate and manufacture method thereof.
Background technology
Radiotherapy (radiotherapy) is one of critical treatment method for tumor.For maximum limit Degree ground reduces radiotherapy side effect and the damage of radiotherapy normal tissue, develops radioactive particle Implanted treatment technology (hereinafter referred to as seeds implanted).
Seeds implanted is a kind of by inside radioactive source implantation tumour, allows it with the treatment of destroyed tumor Means.Seeds implanted treatment technology relates to radioactive source, and its core is radion.Seeds implanted Rely primarily on orientation system by radioactive prospecting instrument tumor body, sent by mini-radioactive resource and hold Continuous, short-range lonizing radiation, make tumor tissues be killed to greatest extent, and normal structure are not Damage or only microlesion.
Current seeds implanted operation is typically to be carried out by rule of thumb by doctor clinically, and this is just to doctor Raw Couple herbs and skill propose the highest requirement.Traditional is carried out under CT is image-guided Inner irradiation operation, due to exist several so that tens, up to a hundred points of puncture, in art substantially It is " blind wear ".It addition, the tumor seeds implanted planning system that currently oneself has is all based on one-dimensional Or bidimensional image data carry out pre-planned to puncturing inserting needle passage, can not calculate the place of particle Prescription amount, after this just often results in seeds implanted, there is " hot-zone " (dosage mistake in inside tumor Cause greatly side effect) and/or the adverse consequences of " cold-zone " (dosage is too small to be caused to no effect).
The information being disclosed in this background section is merely intended to deepen the general background to the present invention The understanding of technology, and be not construed as recognizing or implying this information structure in any form Prior art known to those skilled in the art.
Summary of the invention
The present invention is directed to existing tumor planning software, system and Traditional Man and puncture the defect implanted, According to doctor's requirement to dosage, dosiology algorithm is used to obtain preferred particle cloth source scheme, and Planning inserting needle passage on this basis.Ensureing that radiological dose can effective killing tumor cell Adequately protect health tissues simultaneously, significantly reduces radiocurable side effect.The present invention is three On dimension word model, inserting needle passage is planned, it is possible to evade overwhelming majority normal structure organ (skeleton, blood vessel, nerve etc.), are aided with the conformal template of 3D printing and carry out surgical navigational, While improve operation safety, also greatly reduce the labor intensity of doctor, improve hands Art success rate and therapeutic effect.
The application provides a kind of 3D to print the manufacture method of Wicresoft's guiding die plate, it is characterised in that Described manufacture method comprises the following steps: scanning step, is scanned target site obtaining institute State the 3-D view of target site;Reconstruction step, the described 3-D view reconstruct according to obtaining obtains Obtain the threedimensional model of described target site;Planning step, according to threedimensional model and the doctor of reconstruct Raw requirement plans inserting needle direction, inserting needle position and depth of needle, dosage conformal cloth source particles position Put;Modeling procedure, according to threedimensional model and the inserting needle direction of planning of reconstruct, inserting needle position with And depth of needle, set up guiding die plate mathematical model;Printing step, will by 3D printing technique The printing of described guiding die plate mathematical model becomes 3D and prints Wicresoft's guiding die plate, wherein, described heavy Structure step, described planning step and described modeling procedure utilize treatment planning systems to carry out; In described planning step, the planning of inserting needle direction, inserting needle position and depth of needle be based on The three-dimensional position of normal structure organ is carried out;In described printing step, it is thus achieved that 3D print Wicresoft's guiding die plate is fitted with described target site adaptability.
Preferably, plan inserting needle direction, inserting needle position and depth of needle at described planning step, Dosage conformal cloth source particles position, multiple inserting needle directions that planning obtains.
Preferably, in described planning step, plan that multiple inserting needle direction is with many in three dimensions Individual inserting needle position.
Preferably, multiple inserting needle directions can according to rebuild image data freely evade one or Multiple histoorgans.
Preferably, dosage conformal cloth source particles position, Rapid Dose Calculation is that full 3-dimensional calculates in real time.
The application also provides for a kind of 3D and prints Wicresoft's guiding die plate, and described 3D prints Wicresoft and guides Template is that above-described 3D prints the manufacture method of Wicresoft's guiding die plate and obtains.From another Individual angle is said, be threedimensional model and the inserting needle direction of planning according to reconstruct, inserting needle position and Depth of needle, sets up guiding die plate mathematical model, uses 3D to print the manufacture of Wicresoft's guiding die plate Method and obtain.
The 3D of the present invention prints Wicresoft's guiding die plate and is particularly suitable for tumor seeds implanted, utilizes art The patient image of front acquisition learns data (CT etc.) and sets up three-dimensional three-dimensional digit model, for doctor Radiological dose required for life, by algorithmic rule particle cloth source position, and safely and effectively Plan inserting needle passage under dosage premise, and generation is led for assisting the 3D puncturing inserting needle to print Wicresoft To template.Based on mathematical model, print Wicresoft guiding die plate for auxiliary implementation with 3D, Ensure that safety and puncture needle site, depth of needle, the essence of particle distribution of radiological dose Really property, evades out human body vital tissue simultaneously, decreases doctor and depend on image information in art Rely, reduce labor intensity and difficulty, also for medical reform " classification diagnosis and treatment " at oncotherapy The popularization in field provides objective base.
The 3D of the present invention prints Wicresoft's guiding die plate and is also suitable for applying at argon helium knife ablative surgery With frost ablative surgery on.Such as, utilize the present invention can carry out seeds implanted to combine frost and disappear Melt operation, print needle track and the frost printing applicable seeds implanted on Wicresoft's guiding die plate at 3D The needle track of ablation needle, had not only implanted particle but also had carried out frost in once operation and melted.
By accompanying drawing and detailed description of the invention subsequently, the further feature that the present invention is had and Advantage will become clearer from.
Accompanying drawing explanation
Fig. 1 is the stream that 3D according to embodiments of the present invention prints the manufacture method of Wicresoft's guiding die plate Cheng Tu.
Fig. 2 is the schematic diagram that 3D according to embodiments of the present invention prints Wicresoft's guiding die plate.
Fig. 3 is that 3D according to embodiments of the present invention prints Wicresoft's guiding die plate Conducted Puncture signal Figure.
Detailed description of the invention
Reference will be made in detail now each embodiment of the present invention, the example of these embodiments It is shown in the accompanying drawings and is described as follows.Although the present invention will combine with exemplary It is described, it will be appreciated that this specification is not intended to limit the invention to those Exemplary.On the contrary, it is contemplated that not only cover these exemplary, And cover and can be included in the spirit and scope of the present invention being defined by the appended claims Within various selection forms, modification, equivalents and other embodiment.
Fig. 1 is the stream that 3D according to embodiments of the present invention prints the manufacture method of Wicresoft's guiding die plate Cheng Tu.
3D according to embodiments of the present invention prints the manufacture method of Wicresoft's guiding die plate and includes scanning Step S101, reconstruction step S102, planning step S103, modeling procedure S104 and printing step Rapid S105.
Scanning step S101 includes the 3-D view that target site is scanned obtain target site. This scanning is to use CT scan (CT) equipment or NMR (Nuclear Magnetic Resonance)-imaging (MRI) Equipment is carried out, and target site is lesions position and focus peripheral part, such as include buttocks, Chest, head, cervical region, back, waist, extremity portion or other positions of health.
Reconstruction step S102 includes the three-dimensional obtaining target site according to the 3-D view reconstruct obtained Model.According to the technical characteristic scanned before, reconstruct here can also be to obtain based on scanning Multiple tomographs carry out.
Planning step S103 includes that the threedimensional model according to reconstruct and doctor require to plan inserting needle side To, inserting needle position and depth of needle, dosage conformal cloth source particles position.
Modeling procedure S104 includes the threedimensional model according to reconstruct and the inserting needle direction of planning, inserting needle Position and depth of needle, set up guiding die plate mathematical model.
Printing step S105 includes that being directed to template mathematical model by 3D printing technique is printed as Wicresoft's guiding die plate is printed for 3D.
Reconstruction step S102, planning step S103 and modeling procedure S104 are to utilize treatment plan System (TPS) is carried out.
In planning step S103, the planning of inserting needle direction, inserting needle position and depth of needle is Three-dimensional position based on normal structure organ is carried out.
In printing step S105, it is thus achieved that 3D print Wicresoft guiding die plate and fit with target site Answering property is fitted.3-D view owing to obtaining in scanning step before has comprised mesh The shape and size information at mark position, and these information in follow-up reconstruct, model, print step Having got back in Zhou and transmitted and retain, therefore, the final 3D obtained prints Wicresoft's guiding die plate energy Enough adaptability laminating target sites, thus effectively reduce inserting needle direction, inserting needle position and inserting needle There is the probability of error in the degree of depth, reduces the harmful effect to therapeutic effect.
According to a preferred embodiment of the invention, planning step is planned inserting needle direction, inserting needle position Put and depth of needle, dosage conformal cloth source particles position, multiple inserting needle directions that planning obtains. In planning step, plan multiple inserting needle direction and multiple inserting needle position in three dimensions.Multiple One or more histoorgan can freely be evaded according to the image data rebuild in inserting needle direction.Agent Measuring conformal cloth source particles position, Rapid Dose Calculation is that full 3-dimensional calculates in real time.
According to a preferred embodiment of the invention, planning step S103 plans multiple particle cloth source Position, and accordingly based upon each particle cloth source position planning inserting needle direction, inserting needle position with And depth of needle, multiple inserting needle directions that planning obtains are parallel to each other.Inserting needle side parallel to each other Print and inserting needle behavior to follow-up 3D can be simplified.
According to another preferred embodiment of the invention, in planning step S103, in three dimensions Plan multiple inserting needle direction and multiple inserting needle position.It is to say, be required to adopt according to the state of an illness By different inserting needle forms, such as can be to use multiple inserting needle directions form parallel to each other, also Can its objective is so that inserting needle passage avoids normal structure or organ to use uneven form, Such as prevent inserting needle passage from passing from osseous tissue, thus reduce operation risk, simplify hands Art process.
Fig. 2 is the schematic diagram that 3D according to embodiments of the present invention prints Wicresoft's guiding die plate.According to Template shown in Fig. 2, be provided with laminating patient's CT scan time fixed position anchor point 21 with And CT lower bolster positions line 22, so holding very much with the cross of laser positioning during patient body reset Easily template is resetted.In other words, the locating point position of labelling when anchor point 21 and patient are CT Identical, location line 22 overlaps with CT laser positioning line.The three-dimensional needle track 23 that punctures is to pass through TPS Calculate and design.In seeds implanted treatment operation, particle under corresponding needle track and each needle track Quantity and position are described in prospectus, meet the requirement of seeds implanted treatment.
Fig. 3 is that 3D according to embodiments of the present invention prints Wicresoft's guiding die plate Conducted Puncture signal Figure.In Fig. 3,3D prints the conformal template of Wicresoft 33 and body surface is fitted after fixing, and performs the operation, Owing to taking three-dimensional inserting needle to devise puncture needle track 32, so the piercing process of puncture needle 31 is avoided Blood vessel 34 and skeleton 35 and other normal structure organs, the most accurately arrive in tumor 36 Appropriate location, decrease operating time, reduce patient ailing.
Compared with prior art, the present invention can deposit in technological layer solves seeds implanted operation Inserting needle passage and the problem such as cloth source position is inaccurate, radiological dose is unreasonable;Can be from mark The angle of standardization improves reliability and the curative effect of seeds implanted treatment;Doctor institute can be reduced simultaneously The muscle power that undertakes, energy intensity, greatly reduce operating time and risk, make more doctor permissible Seeds implanted iatrotechnics is implemented in the case of safety is to be fully ensured.
The description that above embodiment specific illustrative to the present invention is presented is in order at explanation and retouches The purpose stated.Description above is not intended to become milli exhaustively, is not intended to this Bright it is limited to disclosed precise forms, it is clear that according to above-mentioned teaching, a lot of changes and change It is all possible.The scope of the present invention is intended to be limited by appended claims and equivalents.

Claims (6)

1. a 3D prints the manufacture method of Wicresoft's guiding die plate, it is characterised in that described system The method of making comprises the following steps:
Scanning step, is scanned obtaining the 3-D view of described target site to target site;
Reconstruction step, the described 3-D view reconstruct according to obtaining obtains the three of described target site Dimension module;
Planning step, threedimensional model and doctor according to reconstruct require to plan inserting needle direction, enter Pin position and depth of needle, dosage conformal cloth source particles position;
Modeling procedure, according to threedimensional model and the inserting needle direction of planning of reconstruct, inserting needle position with And depth of needle, set up guiding die plate mathematical model;
Printing step, is become the printing of described guiding die plate mathematical model by 3D printing technique 3D prints Wicresoft's guiding die plate,
Wherein, described reconstruction step, described planning step and described modeling procedure are to utilize treatment Planning system is carried out;
In described planning step, the planning of inserting needle direction, inserting needle position and depth of needle is Three-dimensional position based on normal structure organ is carried out;
In described printing step, it is thus achieved that 3D print Wicresoft guiding die plate and described target site Adaptability is fitted.
3D the most according to claim 1 prints the manufacture method of Wicresoft's guiding die plate, its It is characterised by, described planning step is planned inserting needle direction, inserting needle position and depth of needle, Dosage conformal cloth source particles position, multiple inserting needle directions that planning obtains.
3D the most according to claim 1 prints the manufacture method of Wicresoft's guiding die plate, its It is characterised by, in described planning step, plans multiple inserting needle direction and multiple in three dimensions Inserting needle position.
3D the most according to claim 3 prints the manufacture method of Wicresoft's guiding die plate, its Being characterised by, multiple inserting needle directions can freely evade one or many according to the image data rebuild Individual histoorgan.
3D the most according to claim 1 prints the manufacture method of Wicresoft's guiding die plate, its Being characterised by, dosage conformal cloth source particles position, Rapid Dose Calculation is that full 3-dimensional calculates in real time.
6. a 3D prints Wicresoft's guiding die plate, it is characterised in that according to the three-dimensional mould of reconstruct Type and the inserting needle direction of planning, inserting needle position and depth of needle, set up guiding die plate numeral mould Type, uses 3D to print the manufacture method of Wicresoft's guiding die plate and obtain.
CN201610620011.9A 2016-08-01 2016-08-01 Three-dimensional printed minimally invasive guide template and making method thereof Pending CN105963002A (en)

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CN106362309A (en) * 2016-09-29 2017-02-01 陕西东望科贸有限公司 Method for customizing tumor radiotherapy baffle
CN106821497A (en) * 2017-03-16 2017-06-13 上海市肺科医院 A kind of target site is accurately positioned and method of disposal and servicing unit
CN106937878A (en) * 2017-04-21 2017-07-11 北京希艾姆医疗器械有限公司 Conformal puncture guide and preparation method thereof
CN107025831A (en) * 2017-06-02 2017-08-08 杭州科霖医疗科技有限公司 A kind of method for making Surgery Simulation model and cervial plexum block anesthesia surgery model
CN108245789A (en) * 2018-03-28 2018-07-06 北京启麟科技有限公司 The transplanting guider of cervical carcinoma close-range treatment Minimally Invasive Surgery
CN108392265A (en) * 2018-02-13 2018-08-14 广西医科大学附属肿瘤医院 A kind of 3D printing Microwave Coagulation Therapy template and preparation method thereof
CN108523999A (en) * 2018-03-21 2018-09-14 山东卓业电子科技有限公司 Intracranial tumour positioning drills, the design method of puncturing operation 3D printing template
CN108720923A (en) * 2018-04-02 2018-11-02 王成功 Householder method is fixed in fracture of calcaneus closed reduction based on digitlization 3D printing tool
CN109011222A (en) * 2018-09-07 2018-12-18 上海黑焰医疗科技有限公司 Body surface positioning guide plate for guiding radioactive particles to perform brachytherapy on cancer and manufacturing method
CN109591284A (en) * 2018-12-27 2019-04-09 杭州先临三维云打印技术有限公司 3D printing electric spark-erosion perforation guide frame, manufacturing method and drilling technology
ES2719279A1 (en) * 2018-01-09 2019-07-09 Cella Medical Solutions Sl GUIDING DEVICE FOR HEPATIC SURGERY (Machine-translation by Google Translate, not legally binding)
CN110141777A (en) * 2019-04-02 2019-08-20 成都真实维度科技有限公司 Radioactive particle source cloth source and needle track paths planning method in knurl
CN110141770A (en) * 2019-04-02 2019-08-20 成都真实维度科技有限公司 The planning of radioactive particle source implant needle path and needle track generation method in a kind of knurl
EP3542742A4 (en) * 2016-11-16 2019-09-25 The Asan Foundation Customized surgical guide and customized surgical guide generating method and generating program
CN110314288A (en) * 2018-09-07 2019-10-11 上海黑焰医疗科技有限公司 Guide the intracavitary positioning guide plate and production method of radion close-range treatment cancer
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CN111588999A (en) * 2020-05-25 2020-08-28 李硕 Operation guide model, head-wearing wearable device-assisted operation navigation system and method
CN111643166A (en) * 2020-06-29 2020-09-11 福建省肿瘤医院(福建省肿瘤研究所、福建省癌症防治中心) 3D template reset control method, system, storage medium, program, and terminal
CN111728679A (en) * 2020-08-21 2020-10-02 真实维度科技控股(珠海)有限公司 Manufacturing method of non-coplanar puncture template with drainage mechanism for 3D printing
CN112245815A (en) * 2020-10-26 2021-01-22 北京航空航天大学 Afterloading radiotherapy plan and 3D printing template integrated simulation design method and system
CN112516471A (en) * 2020-12-01 2021-03-19 北京航空航天大学 Radiotherapy plan simulation design method and system based on expansion and contraction theory
CN112675387A (en) * 2020-12-23 2021-04-20 怀化市第一人民医院 Design method for manufacturing piriformis drug injection puncture guide plate by using 3D printing technology
EP3764917A4 (en) * 2018-05-15 2021-05-05 Cairnsurgical, Inc. Devices for guiding tissue treatment and/or tissue removal procedures
CN113244516A (en) * 2021-07-05 2021-08-13 真实维度科技控股(珠海)有限公司 Non-coplanar puncture template manufacturing method based on bony multipoint positioning and template

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CN105498099A (en) * 2015-11-30 2016-04-20 北京大学第一医院 Preparation method and system of tissue compensator
CN105381534A (en) * 2015-12-28 2016-03-09 上海昕健医疗技术有限公司 Guide plate for seed implantation and manufacturing method and device thereof

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CN106362309A (en) * 2016-09-29 2017-02-01 陕西东望科贸有限公司 Method for customizing tumor radiotherapy baffle
CN106362309B (en) * 2016-09-29 2019-03-22 陕西东望科技有限公司 A method of customization tumour radiotherapy baffle
US11154362B2 (en) 2016-11-16 2021-10-26 The Asan Foundation Customized surgical guide and customized surgical guide generating method and generating program
AU2017361460B2 (en) * 2016-11-16 2020-04-30 The Asan Foundation Customized surgical guide and customized surgical guide generating method and generating program
EP3542742A4 (en) * 2016-11-16 2019-09-25 The Asan Foundation Customized surgical guide and customized surgical guide generating method and generating program
AU2020210171B2 (en) * 2016-11-16 2022-05-26 The Asan Foundation Customized surgical guide and customized surgical guide generating method and generating program
CN106821497A (en) * 2017-03-16 2017-06-13 上海市肺科医院 A kind of target site is accurately positioned and method of disposal and servicing unit
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Application publication date: 20160928