CN105944192A - Device for capturing and removing air bubbles in infusion tube - Google Patents

Device for capturing and removing air bubbles in infusion tube Download PDF

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Publication number
CN105944192A
CN105944192A CN201610307938.7A CN201610307938A CN105944192A CN 105944192 A CN105944192 A CN 105944192A CN 201610307938 A CN201610307938 A CN 201610307938A CN 105944192 A CN105944192 A CN 105944192A
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CN
China
Prior art keywords
ultrasonic
bubble
transfusion
tube
cavitation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610307938.7A
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Chinese (zh)
Inventor
江海
顾守东
路崧
吕庆庆
刘建芳
丁海前
焦晓阳
杨洋
崔建松
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Jilin University
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Jilin University
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Filing date
Publication date
Application filed by Jilin University filed Critical Jilin University
Priority to CN201610307938.7A priority Critical patent/CN105944192A/en
Publication of CN105944192A publication Critical patent/CN105944192A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/36Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests with means for eliminating or preventing injection or infusion of air into body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/36Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests with means for eliminating or preventing injection or infusion of air into body
    • A61M5/365Air detectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M2005/1401Functional features

Abstract

The invention relates to a device for capturing and removing air bubbles in an infusion tube, belonging to the field of precise driving. The device comprises a piezoelectric transducer generating device, a movable reflecting device, an ultrasonic cavitation device, a laser detection feedback device, an ultrasonic generating controller and an ultrasonic cavitation generating controller. The air bubbles in the infusion tube are captured and then enabled to be positioned at the suspension wave nodes by adopting an ultrasonic suspension method, and then the air bubbles are broken by adopting an ultrasonic cavitation method, so that the purpose of capturing and removing the air bubbles in the infusion tube is achieved; the laser detection feedback device is used for identifying the size of the air bubbles in the infusion tube, so that the feedback information is transmitted to the ultrasonic generating controller and the ultrasonic cavitation generating controller. The device for capturing and removing the air bubbles in the infusion tube has the advantages of microminiaturization, integration, use convenience, portability, simple structure and the like.

Description

A kind of capture and remove the device of bubble in tube for transfusion
Technical field
The present invention relates to a kind of capture and remove the device of bubble in tube for transfusion, belong to precision actuation field.
Background technology
It is known that along with the raising maked rapid progress of medical level, the reduction of transfusion cost.Infusion treatment has become as the common people The effective means for the treatment of disease.A kind of medication most commonly seen during wherein venous transfusion is clinical treatment.It is to use drop Method, is directly input into injecting drug use in vein blood vessel, and this application method is the most direct, absorbs fast, instant effect.But transfusion Time its hygienic requirements, safety requirements should be most stringent.Particularly when dropping point, medicinal liquid must not have air pocket, otherwise may make Become in patient vessel to occur vent plug and threat to life.In infusion process, it is commonly encountered aerofluxus not thorough, often has bubble attachment of being scattered In transfusion tube wall.Discharging these bubbles, common method is with finger ceaselessly springing tube for transfusion, makes bubble divide with tube wall From, then float and be rejected in murphy's dropper.Find in operation: this method aerofluxus is steeped, bubble floating difficulty, it is difficult to get rid of dry Only, and expend the regular hour.When main cause is hands ceaselessly springing tube wall, tube for transfusion will continue left and right vibrations, bubble It is similarly subjected to the effect of left and right shaking force and decomposed the strength of floating, thus ascent rate has slowed down.But existing one A little invention devices simply involve how to utilize ultrasound detection principle to the air bubble problem detecting in tube for transfusion, and do not suggest that this is such as What captures it and removes the method and apparatus of tube for transfusion bubble.In order to remove the bubble in tube for transfusion, the present invention proposes one and catches Obtain and go the method and apparatus of bubble removing.This device is to utilize ultrasonic two kind principle to remove bubble, has with conventional method and cuts Right difference.This invention device is the ultrasonic standing wave acoustic pressure utilizing piezoelectric transducer generating means and moveable reflection unit to produce The bubble captured and fix in tube for transfusion is at node;Then the high frequency acoustic pressure that recycling ultrasonic cavitation device produces smashes ripple Bubble in the tube for transfusion captured at joint, thus reach capture and remove the problem of bubble in tube for transfusion.
Summary of the invention
In order to remove bubble present in tube for transfusion, the present invention devises and a kind of captures and remove the device of bubble in tube for transfusion.Should Device utilizes principle that ultrasonic standing wave suspends to screen capture bubble so that it is stable suspersion is at ultrasonic standing wave node.Use the most again The bubble captured is smashed by the principle of ultrasonic cavitation, thus reaches to remove the problem that there is bubble in tube for transfusion.
For reaching object above, the present invention by the following technical solutions: a kind of capture and remove the device of bubble in tube for transfusion, bag Include piezoelectric transducer generating means part, moveable reflection unit part, ultrasonic cavitation device portions and laser detection feedback dress Put.
Piezoelectric transducer generating means part: ultrasonic piezoelectric transducer (200) is by horn (204), nodal section plate (203), two panels Piezoelectric ceramic piece (202) and rear end cap (201) are constituted.By (noticing that two panels potsherd is in structure at two panels piezoelectric ceramic piece (202) Concordance completely should be had in parameter) apply generating positive and negative voltage and can realize the body vibration of ultrasonic piezoelectric transducer (200), then The amplitude of piezoelectric ceramic piece (202) is amplified by horn (204).Thus realize the high frequency vibrating of ultrasonic piezoelectric transducer (200) Dynamic.Ultrasonic piezoelectric transducer (200) is fixed on transducer mount (1) by screw (4).Wherein transducer mount (1) passes through spiral shell Nail (12) is fixed on base (10).Thus constitute a complete fixed piezoelectric transducer generating means.Ultrasonic by changing The frequency of generator controller is mated the frequency of ultrasonic piezoelectric transducer (200) and is at resonance state.By changing ultrasonic The power of raw controller can obtain the ultrasonic standing wave of high intensity.
Movably reflection unit part: the reflection unit that the present invention uses is moveable reflection unit, due to piezoelectric transducer Generating means is in a fixed position, then before needing to clamp tube for transfusion, and a reflectance ultrasound by the moveable reflection unit of regulation Enter the effect of ripple.Movably reflection unit has reflection end (7), XY axle mobile platform (800) and adjusting knob (801) to constitute. Reflection end (7) is fixed in the inside groove of XY axle mobile platform (800), can realize being fixed on XY axle by adjusting knob (801) and move Movement about the reflection end (7) on moving platform (800), front and back is to clamp tube for transfusion to be measured.Wherein XY axle mobile platform (800) It is fixed on base (10) by screw (11).Movably reflection unit and piezoelectric transducer generating means together constitute a set of Complete ultrasonic standing wave generating mechanism.Ultrasonic piezoelectric transducer (200) can be made to be in by the frequency regulating ultrasonic generator controller Resonance state also inspires ultrasonic advancing wave, and advancing wave is reflected end (7) and reflects and be overlapped mutually with advancing wave at node;From And making the vibration velocity at node is zero.Meanwhile, flowing to the bubble in this ultrasonic advancing wave region all can be in the effect of ultrasonic advancing wave Under, elapsed to node by acoustic radiation pressure and stable suspersion is at node, thus realize the capture of bubble in tube for transfusion.
Ultrasonic cavitation device portions: ultrasonic cavitation device portions is for crushing the bubble captured by ultrasonic standing wave in tube for transfusion. Frequency and power by regulation ultrasonic cavitation generator controller can reach different cavitation effect.
As the prioritization scheme of the present invention, ultrasonic cavitation device is by ultrasonic cavitation piezoelectric patches (301), PMMA support (302) and deposition Synthesis flexible material (303) on ultrasonic cavitation piezoelectric patches (301) is constituted.
As the prioritization scheme of the present invention, synthesis flexible material (303) is fixing with PMMA support (302) to be bonded together.
As the prioritization scheme of the present invention, PMMA support (302) is embedded in cavitation support (13), and its cavitation support (13) leads to Cross screw (12) to be stably fixed on base (10).
As the prioritization scheme of the present invention, select synthesis flexible material (303) to be deposited on ultrasonic cavitation piezoelectric patches (301), select Flexible material is to consider that it will not suppress the vibration of ultrasonic cavitation piezoelectric patches (301), also can play connection ultrasonic cavitation piezoelectric patches (301) Bridge with PMMA support.The ultrasonic standing wave that piezoelectric transducer generating means to be utilized and moveable reflection unit produce captures When bubble in tube for transfusion (6) is at node, the acoustic radiation pressure efficiently focused on that recycling ultrasonic cavitation device produces overcomes gas The threshold value of bubble so that it is be crashed to pieces under the effect of positive and negative acoustic pressure.
As the prioritization scheme of the present invention, the present invention also added laser detection feedback device.This device is defeated for detecting identification The size of bubble in liquid pipe, is passed detection signal by laser detection feedback device when Air Bubble Size is in different size scope Deliver to ultrasonic generator controller and ultrasonic cavitation generator controller so that it is be the most automatically adjusted to suitable frequency to excite piezoelectric energy-conversion Device generating means and ultrasonic cavitation device, then produce sizeable standing wave acoustic radiation pressure to capture fixing various sizes of bubble With the cavitation threshold producing different cavitation high frequency acoustic radiation pressures and overcoming different bubble, thus it is the most stingy to reach to remove different size The purpose of bubble.
It is an advantage of the current invention that: ultrasonic standing wave suspension theory be applied in tube for transfusion the capture of bubble fixing in, recycling is super The bubble that the principle of acoustic cavitation is fixed on capture at node crushes.Different frequency can be controlled by laser detection feedback device To realize the broken of different size size bubble, thus successfully achieve the problem of bubble in tube for transfusion of removing.This apparatus structure Simply, miniaturization, the most portable, easily operate, can use whenever and wherever possible, easy for installation.
Accompanying drawing explanation
Fig. 1 is a kind of three dimensional structure schematic diagram capturing and remove the device of bubble in tube for transfusion;
Fig. 2 is a kind of two-dimensional structure schematic diagram capturing and remove the device of bubble in tube for transfusion, and wherein in figure, labelling " 5 " is defeated Bubble in liquid pipe;
Fig. 3 is the detailed structure schematic diagram of ultrasonic piezoelectric transducer and ultrasonic cavitation device;
Fig. 4 is the structural representation of XY axle mobile platform and base fixed form.
Detailed description of the invention
Embodiment
Seeing Fig. 3, ultrasonic piezoelectric transducer (200) is by horn (204), nodal section plate (203), two panels piezoelectric ceramic piece (202) Constitute with rear end cap (201), ultrasonic piezoelectric transducer can be realized by applying generating positive and negative voltage at two panels piezoelectric ceramic piece (202) (200) overall resonance.It should be noted that whole piezoelectric transducer (200) is in resonance mode, but ultrasonic piezoelectric energy-conversion The amplitude at nodal section plate (203) place of device (200) must be zero, and this can be by what design resonance frequency and wavelength ensured.Due to The nodal section plate (203) of ultrasonic piezoelectric transducer (200) is not under vibration mode, therefore can pass through screw (4) ultrasonic piezoelectric energy-conversion Device (200) is fixed on transducer mount (1), and the frequency low-amplitude that two panels piezoelectric ceramic piece (202) produces vibrates via horn (204) vibration of high frequency high-amplitude can be realized.Transducer mount (1) is fixed on base (10) by screw (12).Thus complete The installation of piezoelectric transducer generating means part.Base (10) is to be fixed on lower margin (14) by screw (9).
See Fig. 3, upper deposition synthesis flexible material (303) of ultrasonic cavitation piezoelectric patches (301), then synthesize flexible material (303) It is bonded on PMMA support (302), finally PMMA support (302) interference is embedded in cavitation support (13).Select synthesis soft Property material (303) is because when ultrasonic cavitation piezoelectric patches (301) is in dither, and flexible material will not suppress its piezoelectric patches Vibration, can realize again the connection of piezoelectric patches and rigid support simultaneously.The difference that flexible material is selected, the ultrasonic sky of produced entirety The resonant frequency changing device is different.The design of present invention ultrasonic cavitation to be ensured device, must guarantee that its flexible material will not be relatively The interference of big degree, the vibration of suppression ultrasonic cavitation piezoelectric patches (301).Cavitation support (13) and base can be realized by screw (12) (10) fix, can complete the installation of ultrasonic cavitation device portions.Generally, ultrasonic cavitation device is an overall portion Part, non-dismountable.
Seeing Fig. 2, reflection end (7) is fixed in the inside groove of XY axle mobile platform (800), and XY axle mobile platform (800) passes through spiral shell Nail (11) is fixed on base (10).See Fig. 3, so can complete the installation of moveable reflection unit.Wherein XY axle moves Regulation button (801) on moving platform (800) can realize the left and right of reflection end (7), movement front and back.
When tube for transfusion (6) to be measured is placed on the inner ring of piezoelectric patches (301) of ultrasonic cavitation device, the left end of tube for transfusion (6) Side is close on the inner ring at front end of horn (204) of ultrasonic piezoelectric transducer (200), can be real by rotating regulation button (801) The left and right of existing reflection end (7), movement front and back, thus reach to clamp the effect of tube for transfusion (6).Left end by tube for transfusion (6) Fixing of three positions of face, right side and lower surface, can realize the clamping of tube for transfusion (6).Now, whole is i.e. completed The installation of bright device, is provided with laser detection feedback device near tube for transfusion (6) simultaneously, and this device is for the signal detected Feed back to ultrasonic generator controller and ultrasonic cavitation generator controller so that it is make the purpose that frequency changes accordingly respectively.
After tube for transfusion (6) is fixed between piezoelectric transducer generating means and moveable reflection unit, by regulating ultrasonic generation Controller now piezoelectric transducer generating means will produce the acoustic radiation pressure advancing wave of non-linear high intensity, when this advancing wave passes After casting to moveable reflection unit, the echo that is reflected back through the reflection end (7) of moveable reflection unit will with excite Advancing wave is overlapped mutually, and just forms the node of standing wave in tube for transfusion (6).The state that this node presents be vibration velocity be zero, simultaneously The acoustic radiation pressure of high sound intensity can be formed in region between piezoelectric transducer generating means and moveable reflection unit.Due to transfusion Bubble in pipe can be the most descending along with transfusion under gravity, when bubble flows to advancing wave with echo region, this non- Linear high radiation pressure can overcome the mutual viscous force between bubble and surrounding liquid and inertia force, orders about bubble and changes original track And collecting at node, the restoring force simultaneously produced by standing wave acoustic radiation pressure around node also can pull the descending power of bubble, makes Its suspension is fixed at node.Owing to having powerful acoustic radiation pressure in loud field areas, tube for transfusion flows to the institute in this region There is bubble all the viscous force between self and surrounding liquid and inertia force can be overcome to be passed to node under this acoustic radiation pressure, Thus the bubble that realizes tube for transfusion is the most screened out and suspend and be fixed at node.
Hereafter ultrasonic cavitation generator controller is opened.To be regulated to appropriate frequency time, ultrasonic cavitation device i.e. can be in being total to of high frequency Shaking under mode, and produce the focused sound waves of high intensity, the most this focused sound waves acts on suspension and is fixed on the bubble at node. When effect sound pressure level reach certain value (more than the cavitation threshold of bubble) time, grow when bubble will occur, time and compress Dynamic process.When suction function is in bubble, bubble will be elongated;When positive pressure is in bubble, bubble will be located In compressive state.When cavitation high frequency acoustic radiation pressure reaches certain value (more than the cavitation threshold of bubble), bubble will be crashed to pieces. Thus reach to remove the purpose of bubble in tube for transfusion.According to bubble dynamics, the focusing ultrasonic wave ability that frequency is the highest is the strongest.Cause These apparatus of the present invention should select ultrasonic cavitation device high focusing effect, high-frequency.Cavitation threshold and transfusion due to bubble The diameter of surface tension, viscosity, inertia and bubble closely related.Therefore, before ultrasonic cavitation device is installed, Ji Qian road is defeated Liquid pipe side, this device also added for detecting the laser detection feedback device of bubble size size in identification tube for transfusion, works as inspection The bubble measured, when different size scope, can be sent to ultrasonic generator controller and ultrasonic cavitation signal by this feedback device Generator controller so that it is be automatically adjusted to suitable frequency respectively and carry out excitation ultrasound piezoelectric transducer and be in resonance mode and ultrasonic sky Change device and be in resonance mode, then produce the standing wave acoustic radiation pressure of suitable size to capture various sizes of bubble, and produce not Same cavitation high frequency acoustic radiation pressure overcomes cavitation threshold (cavitation threshold of bubble and the size of bubble of different size bubble Have substantial connection), it is achieved thereby that the purpose that in tube for transfusion, each bubble is all captured and removes.This device when starting to infuse Just need in running order.

Claims (1)

1. capture and remove a device for bubble in tube for transfusion, including 4 part-structures, it is characterised in that: portion Point 1 structure is piezoelectric transducer generating means, and it is by ultrasonic piezoelectric transducer (200), screw (4) and Transducer mount (1) forms, and transducer mount (1) is fixed on base (10) by screw (12);Part 2 Structure is moveable reflection unit, and it is to be made up of reflection end (7) and XY axle mobile platform (800), Wherein XY axle mobile platform (800) is fixed on base (10) by screw (11);Part 1 and part 2 Constitute the mechanism of bubble in standing wave suspension capture tube for transfusion (6) of complete set;Part 3 structure is ultrasonic Cavitation device (300), ultrasonic cavitation device (300) is embedded in cavitation support (13), by screw (12) Realizing the fixing of cavitation support (13) and base (10), base (10) can pass through again screw (9) and be fixed on lower end Lower margin (14) on, this part 3 structure is for smashing the bubble being captured to;Part 4 is laser detection Feedback device, for identifying the size of different bubbles in tube for transfusion, and realizes controlling to remove different size The purpose of bubble.
CN201610307938.7A 2016-05-11 2016-05-11 Device for capturing and removing air bubbles in infusion tube Pending CN105944192A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106940344A (en) * 2017-03-31 2017-07-11 西北工业大学 Integrative ultrasonic sensor and application method for ultrasound tomography system
CN108200525A (en) * 2017-12-13 2018-06-22 中国科学院声学研究所 A kind of system and method for measuring ultrasonic transducer mode of oscillation

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN202802342U (en) * 2012-08-29 2013-03-20 深圳市好克光电仪器有限公司 Infusion pump and bubble detecting device
CN105079923A (en) * 2015-09-16 2015-11-25 苏州市力得医疗器械设备厂 Bubble removing device and application thereof
CN105143835A (en) * 2012-10-02 2015-12-09 弗洛设计声能学公司 Acoustophoretic separation technology using multi-dimensional standing waves
CN205084732U (en) * 2015-07-13 2016-03-16 中国科学院声学研究所 Cavitation cloud microbubble preparation facilities
WO2016054192A1 (en) * 2014-09-30 2016-04-07 Flodesign Sonics, Inc. Acoustophoretic clarification of particle-laden non-flowing fluids

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN202802342U (en) * 2012-08-29 2013-03-20 深圳市好克光电仪器有限公司 Infusion pump and bubble detecting device
CN105143835A (en) * 2012-10-02 2015-12-09 弗洛设计声能学公司 Acoustophoretic separation technology using multi-dimensional standing waves
WO2016054192A1 (en) * 2014-09-30 2016-04-07 Flodesign Sonics, Inc. Acoustophoretic clarification of particle-laden non-flowing fluids
CN205084732U (en) * 2015-07-13 2016-03-16 中国科学院声学研究所 Cavitation cloud microbubble preparation facilities
CN105079923A (en) * 2015-09-16 2015-11-25 苏州市力得医疗器械设备厂 Bubble removing device and application thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106940344A (en) * 2017-03-31 2017-07-11 西北工业大学 Integrative ultrasonic sensor and application method for ultrasound tomography system
CN108200525A (en) * 2017-12-13 2018-06-22 中国科学院声学研究所 A kind of system and method for measuring ultrasonic transducer mode of oscillation

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Application publication date: 20160921