CN105943078A - A medical system based on night heart sound analysis and a method - Google Patents

A medical system based on night heart sound analysis and a method Download PDF

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CN105943078A
CN105943078A CN201610352656.9A CN201610352656A CN105943078A CN 105943078 A CN105943078 A CN 105943078A CN 201610352656 A CN201610352656 A CN 201610352656A CN 105943078 A CN105943078 A CN 105943078A
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sound
audio signal
heart sound
thresholding
heart
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CN105943078B (en
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姚青青
林晓鑫
吕诚聪
孟濬
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Zhejiang University ZJU
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B7/00Instruments for auscultation
    • A61B7/02Stethoscopes
    • A61B7/04Electric stethoscopes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024Detecting, measuring or recording pulse rate or heart rate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4806Sleep evaluation
    • A61B5/4809Sleep detection, i.e. determining whether a subject is asleep or not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4806Sleep evaluation
    • A61B5/4812Detecting sleep stages or cycles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4806Sleep evaluation
    • A61B5/4815Sleep quality
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/74Details of notification to user or communication with user or patient ; user input means
    • A61B5/746Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/56Devices for preventing snoring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00Evaluating a particular growth phase or type of persons or animals
    • A61B2503/04Babies, e.g. for SIDS detection

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Physiology (AREA)
  • Acoustics & Sound (AREA)
  • Cardiology (AREA)
  • Otolaryngology (AREA)
  • Psychiatry (AREA)
  • Signal Processing (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Artificial Intelligence (AREA)
  • Pulmonology (AREA)
  • Nursing (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

The invention provides a medical system based on night heart sound analysis and a method. The system comprises a plurality of audio signal collection devices and a monitoring service terminal. The audio signal collection devices are mounted at different positions of a bed. By collecting and analyzing heart sound source signals and determining the specific positions of heart sound sources with an energy ratio positioning algorithm, night real-time monitoring for people under monitoring can be realized. The system also has the functions of heart sound signal display and storage and heart rate calculation, and can give alarm when the heart rate of a person under monitoring exceeds a normal range, thereby preventing danger. The system and the method can detect the night heart rate, sleep habits and the number of times of turning, and realize radiationless monitoring.

Description

Medical system based on heart sound analysis at night and method
Technical field
The present invention relates to portable medical field, particularly relate to a kind of logical based on the heart at night because of the medical system analyzed and Method.
Background technology
Along with growth in the living standard, modern it is also proposed higher requirement for quality of medical care.Tradition is public Hospital's negligible amounts, skewness between region, it tends to be difficult to meet people's needs for outstanding medical resource. Therefore, portable medical information platform based on Internet of Things arises at the historic moment, it have easy to carry, cost is relatively low, Diagnosing feature accurately, the healthy living for people provides real-time guarantees.
For traditional health monitoring system, owing to the people's different active state among a day will cause Bigger randomness, can cause bigger monitoring error, and traditional health monitoring device is bulky, not portable Band, can not realize monitoring in real time.Owing to people has the time of nearly 1/3rd to be in sleep state, therefore every day Sleep state is the prime time of monitoring health state, has stability height, monitors convenient feature.Night Between Gernral Check-up can in the case of the normal activity not disturbing people, diagnose human body disease state, make Low by safety, energy consumption, it is not necessary to next to the skin to wear, compared to traditional health monitoring device, there is superiority significantly.
Summary of the invention
For problem present in background technology, the present invention proposes a kind of medical system based on heart sound analysis at night And method, people's audio signal under sleep state is acquired by audio collecting device, the audio frequency that will collect Information sends to guarding service end, and monitoring service end carries out analysis and utilization in time to gathering audio-frequency information, monitoring The user interface of service end can store, show the cardiechema signals of people, the heart rate of display people.When the heart rate of people exceedes During the normal cardiac rate scope given, monitoring service end transmission signal sends alarm to alarm module, alarm module.
It is an object of the invention to be realized by following technical scheme: a kind of doctor based on heart sound analysis at night Treatment system, this system includes some audio signal sample devices and monitoring service end.Described audio signal sample fills Being placed in the diverse location of bed, all audio signal sample devices can not be placed in same plane, at the bottom of device Placed side is close in portion, and placed side is smooth.
Described audio signal sample device include casing and be placed in casing first communication module, control unit and Signal amplification module;The surface of casing is embedded with microphone module;Described first communication module is connected with control unit. Microphone module is connected with control unit through signal amplification module.
Described microphone module includes sound probe, electret capacitor microphone and power supply circuits, and sound probe is solid Due to the bottom of casing, being close to desktop or the object placed, sound probe is connected with electret capacitor microphone, Power supply circuits provide power supply for electret capacitor microphone;The audio-frequency information of collection is delivered to by described sound probe Electret capacitor microphone, audio signal is converted into the signal of telecommunication by electret capacitor microphone, amplifies through signal Module is amplified, and is sent to guard service end via first communication module.
Described monitoring service end includes second communication module and data analysis module, described second communication module and One communication module communicates, and described data analysis module receives the audio signal that audio signal sample device gathers, Than localization method, sound source is positioned by energy, thus realize the location of people's cardiechema signals.Described energy ratio Localization method utilizes diverse location audio signal sample device to gather the capacity volume variance of signal to estimate the position of sound source Put, specific as follows:
Assume audio signal sample device XiCoordinate in the threedimensional model of bed is (xi,yi,zi), sound source S Coordinate be (x, y, z), have expression formula according to energy with the proportionate relationship that propagation distance decays:
E 1 E 2 = d 2 2 d 1 2
OrderThenTherefore when r ≠ 1, arranging and understanding above formula is sphere Equation, central coordinate of circle C12(u, v, w) with radius R be:
u = rx 1 - x 2 r - 1 v = ry 1 - y 2 r - 1 w = rz 1 - z 2 r - 1 R = x 2 2 + y 2 2 + z 2 2 - r ( x 1 2 + y 1 2 + z 1 2 ) r - 1 + u 2 + v 2 + w 2
Therefore i.e. can determine that monitored person's cardiechema signals according to the window energy ratio of four audio signal sample devices Three-dimensional space position.
Further, described sound probe for medical auscultation head and rubber hose composition integrative-structure or mike.
Further, described data analysis module, in addition to positioning function, also has the merit analyzing monitored person's heart rate Energy;Heart rate analysis is specific as follows:
(1) audio signal sample device collects cardiechema signals waveform, is sent to guard service end;
(2) monitoring service end uses the method calculating the average Shannon entropy of normalization to extract heart sound envelope;
(3) intercepting of thresholding.The intercepting of described thresholding include the location of thresholding starting point, the location of thresholding terminal, The extraction of thresholding, particularly as follows:
(3.1) location of thresholding starting point: set 2 soft-thresholds, the biggest threshold value Th1 and little according to envelope range value Threshold value Th2.To the amplitude envelope section more than Th1, search for forward on the basis of Th1, until amplitude is less than Th2, The starting point that point is thresholding now.The starting point of described thresholding is divided into the starting point of s1 and the starting point of s2, at a heart In the tone signal cycle, the heart sound that there is twice big amplitude shakes, corresponding first heart sound and second heart sound, s1's Starting mark is in the thresholding starting point of first heart sound, and the starting mark of s2 is in the thresholding starting point of second heart sound.
(3.2) location of thresholding terminal: amplitude is more than the envelope section of Th1, searches for backward with the benchmark of Th1, Until amplitude is less than Th2, the terminal that point is thresholding now.The terminal of described thresholding is divided into the terminal of s1 With the terminal of s2, within a cardiechema signals cycle, there is the heart sound concussion of twice big amplitude, correspondence first Heart sound and second heart sound, the terminal of s1 is marked on the thresholding terminal of first heart sound, and the terminal of s2 is marked on second The thresholding terminal of heart sound.
(3.3) extraction of thresholding: will put 1 between beginning and end, terminal sets to 0 between next starting point.
(4) a heart sound movable complete week is identified according to the time interval between adjacent s1 starting mark Phase, described heart sound activity complete cycle includes first heart sound Ss and second heart sound Sd, described first heart sound Ss Time interval between corresponding s1 starting mark and s1 post, described second heart sound Sd correspondence s2 starting point Time interval between mark and s2 post, according to occurring heart sound activity complete cycle in the unit interval Number of times determines the heart rate of people.
Further, this system also includes that alarm modules, described alarm modules are connected with monitoring service end, when Monitoring service end analyzes heart rate when exceeding given heart rate normal range, then send information to alarm modules, open Dynamic alarm modules, alert sound is sought the help of neighbouring people, is guarded service end simultaneously and send out to guardian Deliver newspaper alarming information, reach the effect guarded in time.
Further, described monitoring service end also includes subscriber interface module, real-time cardiechema signals that display gathers, History cardiechema signals, Current heart rate, history heart rate.
Further, this system also includes the display panel module being embedded in tank surface, and display panel module is single with control Unit is connected, the signal condition that display audio signal sample device gathers.
Further, this system also includes the automatic inflating medicated pillow being connected with monitoring service end;For custodial person For the situation of baby, when the cardiechema signals of baby occurs abnormal, monitoring service end sends signal, starts automatically The aerification function of air pillow, medicated pillow lifts, and makes baby tilt certain angle above the waist, it is to avoid baby is because of neck On one's own account push unable with arm pushes down nose, mouth choker and suffocating of causing;For custodial person for exhaling Inhaling the situation of tract disease patient, when the cardiechema signals of custodial person occurs abnormal, monitoring service end sends signal, Starting the aerification function of automatic inflating medicated pillow, medicated pillow lifts, and makes custodial person tilt certain angle above the waist, keeps away Exempt from custodial person to occur because respiratory tract is by suffocating that polyp compressing causes.
A kind of method utilizing said system to carry out heart sound monitoring at night, the method comprises the following steps:
(1) audio signal sample device is disposed.N (n >=4) audio signal sample device is placed in bed Diverse location, all audio signal sample devices can not be placed in same plane, and placed side must be smooth, will Bottom of device is close to placed side, in order to sound can be good at transmission.
(2) collection of audio signal and transmission.Open audio signal sample device, start to accept monitored person Audio signal, the audio signal that the behavior of the person of being observed or action send via air, overland propagation to audio frequency Signal pickup assembly, is delivered to electret capacitor microphone, electret by sound probe by the audio-frequency information of collection Audio signal is converted into the signal of telecommunication by body capacitance microphone, is amplified through signal amplification module, via first Communication module is sent to guard service end.
(3) sound localization.The data analysis module of monitoring service end receives what audio signal sample device gathered Audio signal, is positioned sound source than localization method by energy, thus realizes the sleep monitor of monitored person. The capacity volume variance that described energy utilizes diverse location audio signal sample device to gather signal than localization method is estimated The position of meter sound source, specific as follows:
Assume audio signal sample device XiIn the threedimensional model of bed, the coordinate in the threedimensional model of bed is (xi,yi,zi), the coordinate of sound source S is that (x, y z), have table according to the proportionate relationship that energy is decayed with propagation distance Reach formula:
E 1 E 2 = d 2 2 d 1 2
OrderThenTherefore when r ≠ 1, arranging and understanding above formula is sphere Equation, central coordinate of circle C12(u, v, w) with radius R be:
u = rx 1 - x 2 r - 1 v = ry 1 - y 2 r - 1 w = rz 1 - z 2 r - 1 R = x 2 2 + y 2 2 + z 2 2 - r ( x 1 2 + y 1 2 + z 1 2 ) r - 1 + u 2 + v 2 + w 2
Therefore the three dimensions of monitored person is i.e. can determine that according to the window energy ratio of four audio signal sample devices Position.
Further, when audio signal sample device quantity is more than four, following different mode can be used true Determine the position of sound source:
A) four audio signal sample devices are arbitrarily chosen, the most totalPlant audio signal sample device selecting party Method;Ask for the locus of sound-source signal under each acquisition method, ask forThe meansigma methods of each locus, Position in this, as final sound-source signal;
B) four audio signal sample devices are arbitrarily chosen, the most totalPlant audio signal sample device selecting party Method;Ask for the locus of sound-source signal under each acquisition method, ask forThe r.m.s. of each locus, Position in this, as final sound-source signal.
The invention has the beneficial effects as follows:
1, the cardiechema signals of detected person can be positioned by present system and method, the historical data of location It is stored in monitoring service end, the sleep habit of monitored person can be reflected and stand up number of times, thus for judging sleep matter Amount provides foundation, and can realize the real-time monitoring at night of custodial person.
2, the present invention does not has the radiation of mobile phone etc. to the monitoring of detected person, in addition to heart sound location, it is also possible to Monitoring infant asphyxia or the precarious position of such as snorer.
3, the present system heart sound signal acquisition analysis to monitored person, determines the Current heart rate of detected person And store, when the heart rate of monitored person exceedes threshold value, system carries out alarm.
4, the present invention is by arranging automatic inflating medicated pillow, when the cardiechema signals of monitored person occurs abnormal, opens The aerification function of dynamic automatic inflating medicated pillow, medicated pillow lifts, it is to avoid the possibility that custodial person suffocates.
Accompanying drawing explanation
Fig. 1 is the structured flowchart of medical system based on heart sound analysis at night;
Fig. 2 is the structured flowchart of audio signal sample device;
Fig. 3 is the probe Energy Decay Curve of actual measurement;
Fig. 4 is system positioning experiment result under four audio signal sample devices;
Fig. 5 is the heart rate analysis schematic diagram of the function of data processing module;
In figure, 1 is microphone module;2 is alarm modules;3 is control unit;4 is signal amplification module; 5 is first communication module;6 is display panel module.
Detailed description of the invention
The invention will be further described with specific embodiment below in conjunction with the accompanying drawings.
As shown in Figure 1, 2, the present invention provides a kind of medical system based on heart sound analysis at night, this system bag Include 4 audio signal sample devices and monitoring service end.Described audio collecting device includes casing and is placed in case Internal first communication module 5, control unit 3 and signal amplification module 4;The surface of casing is embedded with display screen Module 6 and microphone module 1;Described first communication module 5, display panel module 6 all with control unit 3 phase Even.Microphone module 1 is connected with control unit 3 through signal amplification module 4.
As in figure 2 it is shown, described microphone module 1 includes that medical auscultation head, rubber hose, electret capacitor pass Sound device and power supply circuits, medical auscultation head is fixed on the bottom of casing, is close to desktop or the object placed, Being connected with rubber hose, rubber hose other end is connected with electret capacitor microphone, and power supply circuits are electret Condenser microphone provides power supply;Described medical auscultation head gathers audio-frequency information, via rubber hose by audio-frequency information Being delivered to electret capacitor microphone, audio signal is converted into the signal of telecommunication, Jing Guoxin by electret capacitor microphone Number amplification module 4 is amplified, and is sent to guard service end via first communication module 5.
Described monitoring service end includes second communication module and data analysis module, described second communication module and One communication module 5 carries out radio communication, and described data analysis module receives the sound that audio signal sample device gathers Frequently signal, is positioned sound source than localization method by energy.Described energy is more specific as follows than localization method:
As it is shown on figure 3, in the range of error allows, in uniform dielectric, the sphere of sound wave is propagated and is met energy and decline Subtract inverse square law.Assume the signal x that i-th audio signal sample device (i=1,2,3,4) receivesi(t) be:
x i ( t ) = s ( t - τ ) d i + ξ i ( t )
Wherein s (t) is sound-source signal, and τ is propagation delay, and ξ (t) is additive Gaussian noise, diFor i-th audio frequency Signal pickup assembly is to the distance of sound source.Owing to indoor short distance propagation delay is relatively low, in time window [0, W] Inside ignore time delay, when signal to noise ratio is relatively low, if ignoring noise item, the energy that audio signal sample device receives E is:
E i d i 2 = E j d j 2 = ∫ 0 W s 2 ( t ) d t
Understand at the same time in section, the signal energy auscultation head medical with it that different audio signals harvester accepts with The square distance of sound source is inversely proportional to.Based on this conclusion, it is possible to use diverse location gathers the capacity volume variance of signal to be come Estimate sound source position.
Assume audio signal sample device Xi(i=1,2,3.4) coordinate in room is (xi,yi,zi), source of sound S's Coordinate be (x, y, z), have expression formula according to energy with the proportionate relationship that propagation distance decays:
E 1 E 2 = d 2 2 d 1 2
OrderThenTherefore when r ≠ 1, arranging and understanding above formula is ball Face equation, central coordinate of circle C12(u, v, w) be and radius R be:
u = rx 1 - x 2 r - 1
v = ry 1 - y 2 r - 1
w = rz 1 - z 2 r - 1
R = x 2 2 + y 2 2 + z 2 2 - r ( x 1 2 + y 1 2 + z 1 2 ) r - 1 + u 2 + v 2 + w 2
Therefore the three-dimensional space position of sound source is may determine that according to the window energy ratio of four audio signal sample devices, As shown in Figure 4.
Described data analysis module, in addition to positioning function, also has the function analyzing monitored person's heart rate.Described number Principle according to the heart rate analysis function analyzing module is (as shown in Figure 5):
(1) audio signal sample device collects cardiechema signals waveform, is sent to guard service end;
(2) monitoring service end uses the method calculating the average Shannon entropy of normalization to extract heart sound envelope;
(3) intercepting of thresholding.The intercepting of described thresholding include the location of thresholding starting point, the location of thresholding terminal, The extraction of thresholding, particularly as follows:
(3.1) location of thresholding starting point: set 2 soft-thresholds, the biggest threshold value Th1 and little according to envelope range value Threshold value Th2.To the amplitude envelope section more than Th1, search for forward on the basis of Th1, until amplitude is less than Th2, The starting point that point is thresholding now.The starting point of described thresholding is divided into the starting point of s1 and the starting point of s2, at a heart In the tone signal cycle, the heart sound that there is twice big amplitude shakes, corresponding first heart sound and second heart sound, s1's Starting mark is in the thresholding starting point of first heart sound, and the starting mark of s2 is in the thresholding starting point of second heart sound.
(3.2) location of thresholding terminal: amplitude is more than the envelope section of Th1, searches for backward with the benchmark of Th1, Until amplitude is less than Th2, the terminal that point is thresholding now.The terminal of described thresholding is divided into the terminal of s1 With the terminal of s2, within a cardiechema signals cycle, there is the heart sound concussion of twice big amplitude, correspondence first Heart sound and second heart sound, the terminal of s1 is marked on the thresholding terminal of first heart sound, and the terminal of s2 is marked on second The thresholding terminal of heart sound.
(3.3) extraction of thresholding: will put 1 between beginning and end, terminal sets to 0 between next starting point.
(4) a heart sound movable complete week is identified according to the time interval between adjacent s1 starting mark Phase, described heart sound activity complete cycle includes first heart sound Ss and second heart sound Sd, described first heart sound Ss Time interval between corresponding s1 starting mark and s1 post, described second heart sound Sd correspondence s2 starting point Time interval between mark and s2 post, according to occurring heart sound activity complete cycle in the unit interval Number of times determines the heart rate of people.
Described monitoring service end also has the function sent a warning.Monitoring service end is according to the heart collected Rate size, compares with given heart rate normal range, when heart rate has exceeded given heart rate normal orientation, Then system judges to be in an emergency, and sends information to alarm modules 2, starts alarm modules 2, sends warning Sound seeks the help of neighbouring people.
This system also includes the automatic inflating medicated pillow being connected with monitoring service end;It is the feelings of baby for custodial person Condition, when the cardiechema signals of baby occurs abnormal, monitoring service end sends signal, starts automatic inflating medicated pillow Aerification function, medicated pillow lifts, and makes baby tilt certain angle above the waist, it is to avoid baby does not has because of neck and arm Strength is pushed open on one's own account and is pushed down nose, mouth choker and suffocating of causing;Custodial person is suffered from for respiratory tract disease The situation of person, when the cardiechema signals of custodial person occurs abnormal, monitoring service end sends signal, starts automatically The aerification function of air pillow, medicated pillow lifts, and makes custodial person tilt certain angle above the waist, it is to avoid to be guarded Person occurs because respiratory tract is by suffocating that polyp compressing causes.
This automatic inflating medicated pillow effect is specific as follows: 1, play the medicated pillow being pressed on baby for infant asphyxia Support, allow baby avoid the effect suffocated;2, snoring, and vital sign are stopped for snorer is unexpected Faint or time crisis occurs, automatic inflating medicated pillow can automatic inflating, medicated pillow is lifted so that snorer inclines above the waist Tiltedly certain angle, so causes the polyp suffocated will be automatically adjusted to not block the position of trachea.
Automatic inflating medicated pillow is positioned at normal medicated pillow bottom, and the normal medicated pillow of area ratio is big simultaneously, widens below neck. Automatic inflating medicated pillow and monitoring service end form closed loop system, when monitoring service end recognizes danger signal, start The air pump of automatic inflating medicated pillow so that it is inflation, thus avoid danger.
The present invention also provides for a kind of method that base utilizes said system to carry out heart sound monitoring at night, the method include with Lower step:
(1) audio signal sample device is disposed.N (n >=4) audio signal sample device is placed in bed Diverse location, all audio signal sample devices can not be placed in same plane, and placed side must be smooth, will Bottom of device is close to placed side, in order to sound can be good at transmission.
(2) collection of audio signal and transmission.Open audio signal sample device, start to accept monitored person Audio signal, the audio signal that the behavior of the person of being observed or action send via air, overland propagation to audio frequency Signal pickup assembly, gathers audio-frequency information by medical auscultation head, is delivered to by audio-frequency information via rubber hose Electret capacitor microphone, audio signal is converted into the signal of telecommunication by electret capacitor microphone, amplifies through signal Module is amplified, and is sent to guard service end via first communication module.
(3) sound localization.The data analysis module of monitoring service end receives what audio signal sample device gathered Audio signal, is positioned sound source than localization method by energy.Described energy is more specific as follows than localization method:
In uniform dielectric, the sphere of sound wave is propagated and is met energy attenuation inverse square law.Assume i-th audio frequency The signal x that signal pickup assembly receivesi(t) be:
x i ( t ) = s ( t - τ ) d i + ξ i ( t )
Wherein s (t) is sound-source signal, and τ is propagation delay, and ξ (t) is additive Gaussian noise, diFor i-th audio frequency Signal pickup assembly is to the distance of sound source.Owing to indoor short distance propagation delay is relatively low, in time window [0, W] Inside ignore time delay, when signal to noise ratio is relatively low, if ignoring noise item, the energy that audio signal sample device receives E is:
E i d i 2 = E j d j 2 = ∫ 0 W s 2 ( t ) d t
Understand at the same time in section, the signal energy auscultation head medical with it that different audio signals harvester accepts with The square distance of sound source is inversely proportional to.Based on this conclusion, it is possible to use diverse location gathers the capacity volume variance of signal to be come Estimate sound source position.
Assume audio signal sample device XiCoordinate in the threedimensional model of bed is (xi,yi,zi), sound source S Coordinate be (x, y, z), have expression formula according to energy with the proportionate relationship that propagation distance decays:
E 1 E 2 = d 2 2 d 1 2
OrderThenTherefore when r ≠ 1, arrangement understands above formula and is Spherical equation, central coordinate of circle C12(u, v, w) with radius R be:
u = rx 1 - x 2 r - 1 v = ry 1 - y 2 r - 1 w = rz 1 - z 2 r - 1 R = x 2 2 + y 2 2 + z 2 2 - r ( x 1 2 + y 1 2 + z 1 2 ) r - 1 + u 2 + v 2 + w 2
Therefore the three dimensions of monitored person is i.e. can determine that according to the window energy ratio of four audio signal sample devices Position.When audio signal sample device quantity is more than four, the most different modes can be used to determine sound source Position:
A) four audio signal sample devices are arbitrarily chosen, the most totalPlant audio signal sample device selecting party Method;Ask for the locus of sound-source signal under each acquisition method, ask forThe meansigma methods of each locus, Position in this, as final sound-source signal;
B) four audio signal sample devices are arbitrarily chosen, the most totalPlant audio signal sample device selecting party Method;Ask for the locus of sound-source signal under each acquisition method, ask forThe r.m.s. of each locus, Position in this, as final sound-source signal.

Claims (9)

1. a medical system based on heart sound analysis at night, it is characterised in that this system includes some audio frequency Signal pickup assembly and monitoring service end.Described audio signal sample device is placed in the diverse location of bed, all sounds Frequently signal pickup assembly can not be placed in same plane, and bottom of device is close to placed side, and placed side is smooth.
Described audio signal sample device include casing and be placed in casing first communication module, control unit and Signal amplification module;The surface of casing is embedded with microphone module;Described first communication module is connected with control unit. Microphone module is connected with control unit through signal amplification module.
Described microphone module includes sound probe, electret capacitor microphone and power supply circuits, and sound probe is solid Due to the bottom of casing, being close to desktop or the object placed, sound probe is connected with electret capacitor microphone, Power supply circuits provide power supply for electret capacitor microphone;The audio-frequency information of collection is delivered to by described sound probe Electret capacitor microphone, audio signal is converted into the signal of telecommunication by electret capacitor microphone, amplifies through signal Module is amplified, and is sent to guard service end via first communication module.
Described monitoring service end includes second communication module and data analysis module, described second communication module and One communication module communicates, and described data analysis module receives the audio signal that audio signal sample device gathers, Than localization method, sound source is positioned by energy, thus realize the location of people's cardiechema signals.Described energy ratio Localization method utilizes diverse location audio signal sample device to gather the capacity volume variance of signal to estimate the position of sound source Put, specific as follows:
Assume audio signal sample device XiCoordinate in the threedimensional model of bed is (xi,yi,zi), sound source S Coordinate be (x, y, z), have expression formula according to energy with the proportionate relationship that propagation distance decays:
E 1 E 2 = d 2 2 d 1 2
OrderThenTherefore when r ≠ 1, arranging and understanding above formula is sphere Equation, central coordinate of circle C12(u, v, w) with radius R be:
u = rx 1 - x 2 r - 1 v = ry 1 - y 2 r - 1 w = rz 1 - z 2 r - 1 R = x 2 2 + y 2 2 + z 2 2 - r ( x 1 2 + y 1 2 + z 1 2 ) r - 1 + u 2 + v 2 + w 2
Therefore i.e. can determine that monitored person's cardiechema signals according to the window energy ratio of four audio signal sample devices Three-dimensional space position.
A kind of medical system based on heart sound analysis at night the most according to claim 1, it is characterised in that Described sound probe for medical auscultation head and rubber hose composition integrative-structure or mike.
A kind of medical system based on heart sound analysis at night the most according to claim 1, it is characterised in that Described data analysis module, in addition to positioning function, also has the function analyzing monitored person's heart rate;Heart rate analysis has Body is as follows:
(1) audio signal sample device collects cardiechema signals waveform, is sent to guard service end;
(2) monitoring service end uses the method calculating the average Shannon entropy of normalization to extract heart sound envelope;
(3) intercepting of thresholding.The intercepting of described thresholding include the location of thresholding starting point, the location of thresholding terminal, The extraction of thresholding, particularly as follows:
(3.1) location of thresholding starting point: set 2 soft-thresholds, the biggest threshold value Th1 and little according to envelope range value Threshold value Th2.To the amplitude envelope section more than Th1, search for forward on the basis of Th1, until amplitude is less than Th2, The starting point that point is thresholding now.The starting point of described thresholding is divided into the starting point of s1 and the starting point of s2, at a heart In the tone signal cycle, the heart sound that there is twice big amplitude shakes, corresponding first heart sound and second heart sound, s1's Starting mark is in the thresholding starting point of first heart sound, and the starting mark of s2 is in the thresholding starting point of second heart sound.
(3.2) location of thresholding terminal: amplitude is more than the envelope section of Th1, searches for backward with the benchmark of Th1, Until amplitude is less than Th2, the terminal that point is thresholding now.The terminal of described thresholding is divided into the terminal of s1 With the terminal of s2, within a cardiechema signals cycle, there is the heart sound concussion of twice big amplitude, correspondence first Heart sound and second heart sound, the terminal of s1 is marked on the thresholding terminal of first heart sound, and the terminal of s2 is marked on second The thresholding terminal of heart sound.
(3.3) extraction of thresholding: will put 1 between beginning and end, terminal sets to 0 between next starting point.
(4) a heart sound movable complete week is identified according to the time interval between adjacent s1 starting mark Phase, described heart sound activity complete cycle includes first heart sound Ss and second heart sound Sd, described first heart sound Ss Time interval between corresponding s1 starting mark and s1 post, described second heart sound Sd correspondence s2 starting point Time interval between mark and s2 post, according to occurring heart sound activity complete cycle in the unit interval Number of times determines the heart rate of people.
A kind of medical system based on heart sound analysis at night the most according to claim 3, it is characterised in that This system also includes that alarm modules, described alarm modules are connected with monitoring service end, when monitoring service end analysis To heart rate exceed given heart rate normal range time, then send information to alarm modules, start alarm modules, send out Going out warning message sound and seek the help of neighbouring people, monitoring service end sends warning message to guardian simultaneously, reaches Effect to monitoring in time.
A kind of medical system based on heart sound analysis at night the most according to claim 1, it is characterised in that This system also includes the automatic inflating medicated pillow being connected with monitoring service end;When custodial person is baby, When the cardiechema signals of baby occurs abnormal, monitoring service end sends signal, starts the inflation of automatic inflating medicated pillow Function, medicated pillow lifts, and makes baby tilt certain angle above the waist, it is to avoid baby is unable because of neck and arm Push open on one's own account and push down nose, mouth choker and suffocating of causing;It is respiratory disease patient for custodial person Situation, when the cardiechema signals of custodial person occurs abnormal, monitoring service end sends signal, starts automatic inflating The aerification function of medicated pillow, medicated pillow lifts, and makes custodial person tilt certain angle above the waist, it is to avoid custodial person sends out It is raw because respiratory tract is by suffocating that polyp compressing causes.
A kind of medical system based on heart sound analysis at night the most according to claim 1, it is characterised in that Described monitoring service end also includes subscriber interface module, real-time cardiechema signals that display gathers, history cardiechema signals, Current heart rate, history heart rate.
A kind of medical system based on heart sound analysis at night the most according to claim 1, it is characterised in that This system also includes the display panel module being embedded in tank surface, and display panel module is connected with control unit, shows sound Frequently the signal condition that signal pickup assembly gathers.
8. one kind utilizes the method that system described in claim 1 carries out heart sound monitoring at night, it is characterised in that The method comprises the following steps:
(1) audio signal sample device is disposed.N (n >=4) audio signal sample device is placed in bed Diverse location, all audio signal sample devices can not be placed in same plane, and placed side must be smooth, will Bottom of device is close to placed side, in order to sound can be good at transmission.
(2) collection of audio signal and transmission.Open audio signal sample device, start to accept monitored person Audio signal, the audio signal that the behavior of the person of being observed or action send via air, overland propagation to audio frequency Signal pickup assembly, is delivered to electret capacitor microphone, electret by sound probe by the audio-frequency information of collection Audio signal is converted into the signal of telecommunication by body capacitance microphone, is amplified through signal amplification module, via first Communication module is sent to guard service end.
(3) sound localization.The data analysis module of monitoring service end receives what audio signal sample device gathered Audio signal, is positioned sound source than localization method by energy, thus realizes the sleep monitor of monitored person. The capacity volume variance that described energy utilizes diverse location audio signal sample device to gather signal than localization method is estimated The position of meter sound source, specific as follows:
Assume audio signal sample device XiIn the threedimensional model of bed, the coordinate in the threedimensional model of bed is (xi,yi,zi), the coordinate of sound source S is that (x, y z), have table according to the proportionate relationship that energy is decayed with propagation distance Reach formula:
E 1 E 2 = d 2 2 d 1 2
OrderThenTherefore when r ≠ 1, arranging and understanding above formula is sphere Equation, central coordinate of circle C12(u, v, w) with radius R be:
u = rx 1 - x 2 r - 1 v = ry 1 - y 2 r - 1 w = rz 1 - z 2 r - 1 R = x 2 2 + y 2 2 + z 2 2 - r ( x 1 2 + y 1 2 + z 1 2 ) r - 1 + u 2 + v 2 + w 2
Therefore the three dimensions of monitored person is i.e. can determine that according to the window energy ratio of four audio signal sample devices Position.
Method the most according to claim 8, it is characterised in that when audio signal sample device quantity surpasses When crossing four, following different mode can be used to determine the position of sound source:
A) four audio signal sample devices are arbitrarily chosen, the most totalPlant audio signal sample device selecting party Method;Ask for the locus of sound-source signal under each acquisition method, ask forThe meansigma methods of each locus, Position in this, as final sound-source signal;
B) four audio signal sample devices are arbitrarily chosen, the most totalPlant audio signal sample device selecting party Method;Ask for the locus of sound-source signal under each acquisition method, ask forThe r.m.s. of each locus, Position in this, as final sound-source signal.
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