CN105902632A - Extracting method of total glucosides of paeony and extracts of total glucosides of paeony - Google Patents
Extracting method of total glucosides of paeony and extracts of total glucosides of paeony Download PDFInfo
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- CN105902632A CN105902632A CN201610413944.0A CN201610413944A CN105902632A CN 105902632 A CN105902632 A CN 105902632A CN 201610413944 A CN201610413944 A CN 201610413944A CN 105902632 A CN105902632 A CN 105902632A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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Abstract
The invention provides an extracting method of total glucosides of paeony. The method includes the steps that paeony is taken, water accounting for 10 times of the weight of the paeony medicine material is added, paeony is soaked for 0.5 h and decocted for 1 h, filtering is conducted, medicine dregs are added to water accounting for 8 times of the weight of the medicine material and decocted for 1 h, and liquid medicine is obtained through filtering. Extracts of total glucosides of paeony are prepared through a specific concentration and drying device and are high in content.
Description
Technical field
The present invention relates to technical field of extraction of Chinese traditional medicine, the extracting method and the Radix Paeoniae Alba total glucosides that are specifically related to a kind of Radix Paeoniae Alba total glucosides extract
Thing.
Background technology
Radix Paeoniae Alba total glucosides is to obtain from Radix Paeoniae Alba dry root, containing peoniflorin (paeoniflorin), Hydroxy peoniflorin
(hydroxy-paeoniflorin), peonin (paeonin), lactone glucoside of Radix Paeoniae (albiflorin), benzoylpaeoniflorin
Etc. (benzoylpaeoniflorin) there is the mixture of physiological function composition, general name Radix Paeoniae Alba total glucosides (total glucosides of
Paeonia, TGP).Wherein, the content of peoniflorin accounts for more than the 90% of total glycosides.Extracting method of the prior art,
Technique is coarse, backward, and impurity is many, and active constituent content is low, causes patient's consumption excessive, it has not been convenient to take, serious shadow
Ring this product to apply clinically.
Summary of the invention
Goal of the invention: in order to solve the problems referred to above, it is an object of the invention to provide the extracting method of a kind of Radix Paeoniae Alba total glucosides.
Technical scheme: it is an object of the invention to by following scheme realization:
The extracting method of a kind of Radix Paeoniae Alba total glucosides, takes the Radix Paeoniae Alba, adds the water of 10 times of weight of white Peony Root, soaks 0.5h, decocts
1 hour, filtering, medicinal residues add the water of 8 times of weight of medical material, decoct 1 hour, and medicinal liquid leaches, and merges twice decoction
Liquid, being concentrated into 60 DEG C of relative densities is 1.05, adds ethanol and makes the percent by volume of alcohol content reach 75%, stirs, stand,
Filtering, when filtrate is concentrated into 65 DEG C, relative density is 1.25, and reclaims ethanol, obtains concentrated solution, uses microwave extracting,
Obtain extract, continue to concentrate, concentrated solution is dried, obtains peony root total glycosides extract.
The extracting method of described Radix Paeoniae Alba total glucosides, described microwave assisted extraction methods is: put into micro-by the concentrated solution after water extract-alcohol precipitation
Ripple extraction equipment carries out microwave extracting, extracts power 400-600W, extract 2 times, each 4-8 minute, add every time
Amount is concentrated solution weight 2 times of 70% ethanol, obtain extract, concentrate.
The extracting method of described Radix Paeoniae Alba total glucosides, described microwave extracting power 500W, every time extraction 6 minutes.
The extracting method of described Radix Paeoniae Alba total glucosides, concentrates for above-mentioned three times and uses device, including tank body, be arranged on described tank body
On charging aperture and be arranged on the discharge nozzle of described tank base, in described tank body, be provided with shaft, at described shaft
It is provided with stirring paddle, is provided with the stirring motor being connected with described shaft at the top of described tank body, at described tank body
Inwall is provided with annular groove, and the bottom of described annular groove, near the diapire of described tank body, sets in described annular groove
There is ring rotation block, in the sidewall of described tank body, be provided with driving motor, the main shaft of described driving motor is provided with driving
Fluted disc, is provided with the teeth groove mutually ratcheting with described driving fluted disc on the outer ring surface of described ring rotation block, in described annular rotation
Be uniformly provided with at least three on the inner ring surface of switch block and scrape muscle, described in scrape the diapire of muscle and be pressed on the diapire upper surface of described tank body
On, described tank body is provided with the actuator being connected with described driving motor.
The extracting method of described Radix Paeoniae Alba total glucosides, the roof of annular groove described in above-mentioned enrichment facility and diapire are uniformly provided with rolling
Pearl, upper surface and the lower surface of described ring rotation block are pressed on described ball.
The extracting method of described Radix Paeoniae Alba total glucosides, the connection of ring rotation block described in above-mentioned enrichment facility and described annular groove
Face is provided with sealing metal bar, and described ball is arranged on the medial extremity of described sealing metal bar and annular groove.
The extracting method of described Radix Paeoniae Alba total glucosides, discharge nozzle described in above-mentioned enrichment facility is additionally provided with cooler, at described tank
Internal it is provided with moisture determination instrument.
The extracting method of described Radix Paeoniae Alba total glucosides, above-mentioned dry use device, including casing, it is arranged in described casing
Material frame and the blast pipe and the discharge pipe that are arranged on described casing top, it is characterised in that: set in the sidewall of described casing
There is the air intake passage being connected with described blast pipe, the sidewall of described casing is provided with and is connected with described air intake passage
Air holes, described discharge pipe through in the roof connection casing of described casing with casing outside, in the sidewall of described casing also
Be provided with homoiothermic chamber and sterilization chamber, be provided with electrical heating block at described homoiothermic intracavity, described air intake passage through described regulation chamber and
Sterilization chamber is arranged, and is provided with rotating drum, is provided with electric rotating machine, described rotation in described rotating drum in the diapire of described casing
The main shaft of rotating motor is connected with described material frame, is provided with vibrations groove in described material frame, on the top of described material frame
Face is provided with and holds plate, is provided with shaking device described holding between plate and described vibrations groove.
The extracting method of described Radix Paeoniae Alba total glucosides, shaking device described in above-mentioned dry use device includes driving motor, arranges
Eccentric on described driving electric machine main shaft, the wheel limit of described eccentric be pressed on described in hold the bottom center of plate,
Being provided with extension spring between the diapire of the described bottom holding plate and described vibrations groove, described extension spring is centered by described eccentric
It is symmetrical arranged.
The extracting method of described Radix Paeoniae Alba total glucosides, is provided with temperature sensor, in institute in casing described in above-mentioned dry use device
The driver being connected with described temperature sensor, described driver and described electrical heating block it is provided with in stating the sidewall of casing
Control end to be connected, described casing is additionally provided with chamber door.
In prior art, Radix Paeoniae Alba total glucosides uses the method for alcohol extraction, and technique is coarse, backward, and impurity is many, causes patient to use
Measuring excessive, it has not been convenient to take, Radix Paeoniae Alba total glucosides yield prepared by the present invention increases, and content is high, and purity reaches 97-99%.This
Concentrator simple in construction in invention, simple operation, when heating concentrates, can drive annular rotation by driving motor
Switch block rotates, and scrapes in the bottom surface of tank body so that scraping muscle, thus can effectively prevent the diapire of tank body from luming, certain journey
Heating thickening efficiency can be improved on Du, solve the tank bottoms easy caking of conventional art Chinese medicinal concentration equipment thus affect and add thermal effect
The technical deficiency of rate, stability in use is good, and the stable effective ingredients of medicine is not destroyed.This drying equipment structure is simple,
Simple and quick, it uses wall box to blow, and is additionally arranged electrical heating block, can enter according to the temperature in case
Row regulation, thus ensure that the stability of baking temperature, and it is provided with electric rotating machine and shaking device, can be in heating
Rotate and shake holding plate simultaneously, thus medicine local desiccation can be prevented, thus can improve dry to a certain extent
Efficiency, solve the technical deficiency that the drying device drying efficiency of conventional art is low.
Accompanying drawing explanation
In order to make present disclosure be more likely to be clearly understood, below according to specific embodiment and combine accompanying drawing, right
The present invention is described in further detail, wherein:
Fig. 1 is the structural representation of enrichment facility of the present invention.
Fig. 2 is the structural representation of drying device of the present invention.
Detailed description of the invention
Form by the following examples, is described in further detail the foregoing of the present invention again, but should be by this
It is interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to Examples below, all technology realized based on foregoing of the present invention
Belong to the scope of the present invention.
Embodiment 1
Take Radix Paeoniae Alba 1000g, add the water of 10 times of weight of white Peony Root, soak 0.5h, decoct 1 hour, filter, medicinal residues
Adding the water of 8 times of weight of medical material, decoct 1 hour, medicinal liquid leaches, and merges twice decoction liquor, is concentrated into 60 DEG C relatively
Density is 1.05, adds ethanol and makes the percent by volume of alcohol content reach 75%, and stirring, standing, filtration, filtrate is concentrated into
When 65 DEG C, relative density is 1.25, and reclaims ethanol, obtains concentrated solution, uses microwave extracting, obtains extract, continues to concentrate,
Concentrated solution is dried, obtains peony root total glycosides extract.
The extracting method of described Radix Paeoniae Alba total glucosides, described microwave assisted extraction methods is: put into micro-by the concentrated solution after water extract-alcohol precipitation
Ripple extraction equipment carries out microwave extracting, extracts power 400W, extract 2 times, each 8 minutes, the 70% of addition every time
The amount of ethanol is 2 times of medical material weight, obtains extract, concentrates.
See Fig. 1: the extracting method of described Radix Paeoniae Alba total glucosides, above-mentioned No. three enrichment facilities, including tank body 1, be arranged on described
Charging aperture on tank body 12 and be arranged on the discharge nozzle 3 bottom described tank body 1, is provided with shaft in described tank body 1
4, described shaft 4 is provided with stirring paddle 5, is provided with at the top of described tank body 1 and to be connected with described shaft 4
Stirring motor 6, is provided with annular groove 7 on the inwall of described tank body 1, and the bottom of described annular groove 7 is near described
The diapire of tank body 1, is provided with ring rotation block 8 in described annular groove 7, is provided with and drives in the sidewall of described tank body 1
Galvanic electricity machine 9, is provided with driving fluted disc 10, at the outer ring surface of described ring rotation block 8 on the main shaft of described driving motor 9
It is provided with the teeth groove 11 mutually ratcheting with described driving fluted disc 10, the inner ring surface of described ring rotation block 8 is uniformly provided with
Article at least three, scrape muscle 12, described in scrape the diapire of muscle 12 and be pressed on the diapire upper surface of described tank body 1, at described tank body
1 is provided with the actuator 13 being connected with described driving motor 9, and actuator is to have used structure on market, it is only necessary to press
Connect according to its connection request and use.In use by controlling driving motor, make driving driven by motor ring rotation block
Rotating, scraping, such that it is able to oar accumulates in tank so that scraping the muscle diapire end face at tank body under the drive of ring rotation block
Pine scraped by the medicinal residues of body diapire end face, thus can prevent caking.
Roof and diapire at described annular groove 7 is uniformly provided with ball 14, the upper surface of described ring rotation block 8 and
Lower surface is pressed on described ball 14.It is provided with ball, it is ensured that the normal rotation of ring rotation block, reduces annular
Friction between spill spin block and annular groove, thus improve service life and stability in use.
The described ring rotation block 8 joint face with described annular groove 7 is provided with sealing metal bar 15, described ball
It is arranged on the medial extremity of described sealing metal bar and annular groove.
Described discharge nozzle is additionally provided with cooler 16, in described tank body, is provided with moisture determination instrument 17.
See Fig. 2: the extracting method of described Radix Paeoniae Alba total glucosides, above-mentioned dry use device, including casing 1, be arranged on described
Material frame 2 in casing 1 and the blast pipe 3 and the discharge pipe 4 that are arranged on described casing 1 top, at described casing 1
Be provided with the air intake passage 5 being connected with described blast pipe 3 in sidewall, the sidewall of described casing 1 is provided with described enter
The air holes 6 that wind passage 5 is connected, fresh air inlet is arranged on sidewall, it is ensured that the uniformity of ventilation, and can be big
Raising and the contact area of medicine greatly, described discharge pipe 4 is through the interior and casing 1 of roof connection casing 1 of described casing 1
Outside, is additionally provided with homoiothermic chamber 7 and sterilization chamber 8 in the sidewall of described casing 1, is provided with electricity and adds in described homoiothermic chamber 7
Hot block 9, being provided with electrical heating block can be adjusted the temperature of blast pipe as required, it is ensured that the stability of baking temperature,
Described air intake passage 5 is arranged through described regulation chamber 7 and sterilization chamber 8, is provided with rotating drum in the diapire of described casing 1
10, in described rotating drum 10, it is provided with electric rotating machine 11, the main shaft of described electric rotating machine 11 is connected with described material frame 2
Connecing, be provided with vibrations groove 12 in described material frame 2, the end face at described material frame 2 is provided with and holds plate 13, in institute
State to hold and be provided with shaking device 14 between plate 13 and described vibrations groove 12.
Described shaking device 14 includes driving motor 141, is arranged on the eccentric 142 on described driving motor 141 main shaft,
The wheel limit of described eccentric 142 holds the bottom center of plate 13, in the described bottom holding plate 13 and institute described in being pressed on
Stating and be provided with extension spring 15 between the diapire of vibrations groove 12, described extension spring is symmetrical arranged centered by described eccentric, makes
Used time makes to hold plate rising by compressing of eccentric, when the recess of eccentric compresses and holds plate, holds plate in extension spring
Effect is lower to be resetted, and makes the disengaging of thing material fall after holding plate again and holding the vibrations realizing material on plate in dropping process.
In described casing 1, it is provided with temperature sensor 16, is provided with in the sidewall of described casing and described temperature sensor
The driver 17 being connected, described driver is connected with the control end of described electrical heating block.Temperature passes dry device and driver
For prior art existing on market, it has only to when using and connecting connect according to corresponding connection description.
Described casing is additionally provided with chamber door 18.
Embodiment 2
Take Radix Paeoniae Alba 1000g, add the water of 10 times of weight of white Peony Root, soak 0.5h, decoct 1 hour, filter, medicinal residues
Adding the water of 8 times of weight of medical material, decoct 1 hour, medicinal liquid leaches, and merges twice decoction liquor, is concentrated into 60 DEG C relatively
Density is 1.05, adds ethanol and makes the percent by volume of alcohol content reach 75%, and stirring, standing, filtration, filtrate is concentrated into
When 65 DEG C, relative density is 1.25, and reclaims ethanol, obtains concentrated solution, uses microwave extracting, obtains extract, continues to concentrate,
Concentrated solution is dried, obtains peony root total glycosides extract.
The extracting method of described Radix Paeoniae Alba total glucosides, described microwave assisted extraction methods is: put into micro-by the concentrated solution after water extract-alcohol precipitation
Ripple extraction equipment carries out microwave extracting, extracts power 600W, extract 2 times, each 4 minutes, the 70% of addition every time
The amount of ethanol is 2 times of concentrated solution weight, obtains extract, concentrates.
Concentrate with drying device ibid.
Embodiment 3
Take Radix Paeoniae Alba 1000g, add the water of 10 times of weight of white Peony Root, soak 0.5h, decoct 1 hour, filter, medicinal residues
Adding the water of 8 times of weight of medical material, decoct 1 hour, medicinal liquid leaches, and merges twice decoction liquor, is concentrated into 60 DEG C relatively
Density is 1.05, adds ethanol and makes the percent by volume of alcohol content reach 75%, and stirring, standing, filtration, filtrate is concentrated into
When 65 DEG C, relative density is 1.25, and reclaims ethanol, obtains concentrated solution, uses microwave extracting, obtains extract, continues to concentrate,
Concentrated solution is dried, obtains peony root total glycosides extract.
The extracting method of described Radix Paeoniae Alba total glucosides, described microwave assisted extraction methods is: put into micro-by the concentrated solution after water extract-alcohol precipitation
Ripple extraction equipment carries out microwave extracting, extracts power 500W, extract 2 times, each 6 minutes, the 70% of addition every time
The amount of ethanol is 2 times of concentrated solution weight, obtains extract, concentrates.
Concentrate with drying device ibid.
In above-described embodiment, the Radix Paeoniae Alba is the root of dicotyledon medicine ranunculaceae plant Radix Paeoniae.
Embodiment 4: paeoniflorin content determination experiment research data in peony root total glycosides extract of the present invention
1.1 Experimental agents: peony root total glycosides extract of the present invention: prepare by embodiment 1-3 method.Matched group uses common concentration
Method prepares peony root total glycosides extract.
1.2 instruments: high performance liquid chromatograph system includes high performance liquid chromatograph (Waters 515)；P200 high-pressure pump；Waters
2487 UV-detector and GJ605 type high pressure six-way injection valve；Chromatographic column is Alltima C18 chromatographic column (150mm × 4.6
mm,5μm)；Data acquisition and process use HS Data Processing in Chromatography Workstation V4.0+ (Hangzhou English spectrum science and technology)
1.3 condition determinations: measure according to high performance liquid chromatography (Chinese Pharmacopoeia two annex V D of version in 2000).Chromatographic condition
It is filler with system suitability octadecylsilane chemically bonded silica；Phosphate buffer [0.05mol/L phosphoric acid hydrogen
Dipotassium liquid-0.05mol/L potassium dihydrogen phosphate solution (80:20), pH value is 7.4]-methanol (65:35) is flowing phase；Detection wavelength
For 230nm.Number of theoretical plate is calculated by peoniflorin peak should be not less than 1500, and peoniflorin peak should meet with the separating degree of adjacent peak
Requirement.Take this product about 20mg, accurately weighed, put in 10ml measuring bottle, add 50% methanol and dissolve and be diluted to scale, shake
Even, precision measures 20 μ l, injects chromatograph of liquid, records chromatogram；Separately take peoniflorin reference substance appropriate, add 50%
Methanol dissolves and quantitatively the solution in every 1ml containing 1mg is made in dilution, is measured in the same method, by external standard method with calculated by peak area,
Obtain.
1.4 experimental result
Paeoniflorin content measurement result in peony root total glycosides extract prepared by each embodiment of table 1
| Sample source | Paeoniflorin content (%) |
| Embodiment 1 | 97 |
| Embodiment 2 | 99 |
| Embodiment 3 | 98 |
| Matched group | 63 |
According to the result of the test of table 1, paeoniflorin content in peony root total glycosides extract prepared by embodiment of the present invention 1-3
Apparently higher than matched group.
Claims (10)
1. the extracting method of a Radix Paeoniae Alba total glucosides, it is characterised in that take the Radix Paeoniae Alba, adds the water of 10 times of weight of white Peony Root, soaks 0.5h,
Decocting 1 hour, filter, medicinal residues add the water of 8 times of weight of medical material, decoct 1 hour, and medicinal liquid leaches, and merges twice decoction
Liquid, being concentrated into 60 DEG C of relative densities is 1.05, adds ethanol and makes the percent by volume of alcohol content reach 75%, stirs, stand, filter,
When filtrate is concentrated into 65 DEG C, relative density is 1.25, and reclaims ethanol, obtains concentrated solution, uses microwave extracting, obtains extract, continue
Continuous concentration, is dried concentrated solution, obtains peony root total glycosides extract.
The extracting method of Radix Paeoniae Alba total glucosides the most according to claim 1, it is characterised in that described microwave assisted extraction methods is: carried by water
Concentrated solution after precipitate with ethanol puts into and carries out microwave extracting in microwave extracting apparatus, extracts power 400-600W, extracts 2 times, each 4-8
Minute, amount is concentrated solution weight 2 times of 70% ethanol every time added, obtain extract, concentrate.
The extracting method of Radix Paeoniae Alba total glucosides the most according to claim 2, it is characterised in that described microwave extracting power 500W, every time
Extract 6 minutes.
The extracting method of Radix Paeoniae Alba total glucosides the most according to claim 1, it is characterised in that concentrate for above-mentioned three times and use device, including
Tank body, the charging aperture being arranged on described tank body and the discharge nozzle being arranged on described tank base, be provided with stirring in described tank body
Axle, is provided with stirring paddle on described shaft, is provided with the stirring motor being connected with described shaft at the top of described tank body,
Being provided with annular groove on the inwall of described tank body, the bottom of described annular groove is near the diapire of described tank body, in described annular
It is provided with ring rotation block in groove, in the sidewall of described tank body, is provided with driving motor, the main shaft of described driving motor is provided with
Drive fluted disc, the outer ring surface of described ring rotation block is provided with the teeth groove mutually ratcheting with described driving fluted disc, in described annular rotation
Be uniformly provided with at least three on the inner ring surface of switch block and scrape muscle, described in scrape the diapire of muscle and be pressed on the diapire upper surface of described tank body,
Described tank body is provided with the actuator being connected with described driving motor.
The extracting method of Radix Paeoniae Alba total glucosides the most according to claim 4, it is characterised in that annular groove described in above-mentioned enrichment facility
Roof and diapire be uniformly provided with ball, upper surface and the lower surface of described ring rotation block are pressed on described ball.
The extracting method of Radix Paeoniae Alba total glucosides the most according to claim 4, it is characterised in that ring rotation described in above-mentioned enrichment facility
Block is provided with sealing metal bar with the joint face of described annular groove, and described ball is arranged on described sealing metal bar and annular groove
Medial extremity.
The extracting method of Radix Paeoniae Alba total glucosides the most according to claim 4, it is characterised in that on discharge nozzle described in above-mentioned enrichment facility
It is additionally provided with cooler, in described tank body, is provided with moisture determination instrument.
The most according to claim 1, the extracting method of Radix Paeoniae Alba total glucosides, it is characterised in that above-mentioned dry use device, including case
Body, the material frame being arranged in described casing and the blast pipe and the discharge pipe that are arranged on described casing top, it is characterised in that:
Be provided with the air intake passage being connected with described blast pipe in the sidewall of described casing, the sidewall of described casing is provided with described enter
The air holes that wind passage is connected, described discharge pipe through described casing roof connection casing in casing outside, at described casing
Sidewall in be additionally provided with homoiothermic chamber and sterilization chamber, be provided with electrical heating block at described homoiothermic intracavity, described air intake passage pass described tune
Joint chamber and sterilization chamber are arranged, and be provided with rotating drum, be provided with electric rotating machine in described rotating drum in the diapire of described casing, described
The main shaft of electric rotating machine is connected with described material frame, is provided with vibrations groove in described material frame, at the end face of described material frame
It is provided with and holds plate, be provided with shaking device described holding between plate and described vibrations groove.
The extracting method of Radix Paeoniae Alba total glucosides the most according to claim 8, it is characterised in that shake described in above-mentioned dry use device
Device includes driving motor, is arranged on the eccentric on described driving electric machine main shaft, and the wheel limit of described eccentric is pressed on described Sheng
Putting the bottom center of plate, be provided with extension spring between the diapire of the described bottom holding plate and described vibrations groove, described extension spring is with institute
It is symmetrical arranged centered by stating eccentric.
The extracting method of Radix Paeoniae Alba total glucosides the most according to claim 8, it is characterised in that case described in above-mentioned dry use device
Internal be provided with temperature sensor, in the sidewall of described casing, be provided with the driver being connected with described temperature sensor, described in drive
Dynamic device is connected with the control end of described electrical heating block, is additionally provided with chamber door on described casing.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106083982A (en) * | 2016-06-14 | 2016-11-09 | 南京市建邺区景春堂电子商务中心 | The extracting method of a kind of platycodin and platycodin extract |
| CN108079077A (en) * | 2018-01-22 | 2018-05-29 | 赵双龙 | Treat the preparation method of the tablet of ostalgia |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102188503A (en) * | 2010-03-19 | 2011-09-21 | 傅宏征 | Preparation method of total glucosides from Paeonia lactiflora Pall., and Paeonia lactiflora Pall. total glucoside preparation and use thereof |
-
2016
- 2016-06-14 CN CN201610413944.0A patent/CN105902632A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102188503A (en) * | 2010-03-19 | 2011-09-21 | 傅宏征 | Preparation method of total glucosides from Paeonia lactiflora Pall., and Paeonia lactiflora Pall. total glucoside preparation and use thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106083982A (en) * | 2016-06-14 | 2016-11-09 | 南京市建邺区景春堂电子商务中心 | The extracting method of a kind of platycodin and platycodin extract |
| CN108079077A (en) * | 2018-01-22 | 2018-05-29 | 赵双龙 | Treat the preparation method of the tablet of ostalgia |
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Application publication date: 20160831 |