CN105877733A - Bioelectric measurement apparatus for general medical practitioners - Google Patents

Bioelectric measurement apparatus for general medical practitioners Download PDF

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Publication number
CN105877733A
CN105877733A CN201510004676.2A CN201510004676A CN105877733A CN 105877733 A CN105877733 A CN 105877733A CN 201510004676 A CN201510004676 A CN 201510004676A CN 105877733 A CN105877733 A CN 105877733A
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China
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measurement
bioelectricity
bioelectric
electrode
instrument
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CN201510004676.2A
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Chinese (zh)
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吴明赞
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Nanjing University of Science and Technology
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Nanjing University of Science and Technology
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Priority to CN201510004676.2A priority Critical patent/CN105877733A/en
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Abstract

The invention discloses a bioelectricity measurement apparatus for general medical practitioners. The bioelectricity measurement apparatus comprises electrodes (1), a signal conditioning circuit (2), a data acquisition card (3), an apparatus driver (4), panel program (5), application program (6), a virtual apparatus development platform (7), a portable PC (8), electronic medical records (9) and bioelectricity measurement files (10). The bioelectricity measurement apparatus is characterized in that the electrodes (1) are mounted at to-be-measured bioelectricity parts of a human body; weak bioelectricity signals are amplified by the signal conditioning circuit (2), and amplified bioelectricity signals are transmitted to the data acquisition card (3); the apparatus driver (4), the panel program (5), the application program (6) and the virtual apparatus development platform (7) software are installed on the portable PC (8), and operation interface of the bioelectricity measurement apparatus for operating the whole apparatus is developed on the portable PC (8); meanwhile, bioelectricity measurement records are automatically generated and are converted into the medical records (9) and the bioelectricity measurement files (10) according to measurement results. The bioelectricity measurement apparatus implements synchronous measurement of various bioelectricities of the human body; on one apparatus, measurement of electroencephalography, electromyography, electrooculography (including retina electrography and nystagmus) and electrogastrography is synchronously achieved.

Description

A kind of bioelectric measurement instrument of general practitioner
Technical field
The present invention relates to the Medical measuring instrument device of a kind of applicable general practitioner.
Background technology
Bio-electric phenomenon is the fundamental characteristics of vital movement, and nearly all life process is all along with bioelectric generation, bio electricity It it is the important information of the reflection various physiological status of human body.Bioelectric researchs various to human body, record become grasp bodily fuctions, Clinical diagnosis and the reliable basis for the treatment of.
But in reality, various bioelectric measurement instruments, it measures function is all single, such as electrocardiograph, electroencephalograph, flesh figure Machine, eye electricity (containing retina electricity and nystagmus), stomach electricity etc., it is impossible to carry out human body various bio electricity synchro measure, can only make in hospital With, general practitioner is usually with outpatient service formal layout commonly encountered diseases, frequently-occurring disease and a many-side people of general emergency case, due to general practitioner duty The particularity of industry, it would be highly desirable to exploitation is suitable for general practitioner occupational characteristic and the bioelectric measurement instrument being actually needed.
Summary of the invention
The present invention discloses the bioelectric measurement instrument of a kind of general practitioner, is (containing retina electricity and eye by brain electricity, myoelectricity, eye electricity Shake), stomach electricity on measuring, there is same procedure and principle is integrated into a measuring instrument, creatively apply virtual instrument technique, Develop the bioelectric measurement instrument that applicable general practitioner occupational characteristic uses, carry out human body various bio electricity synchro measure, concrete skill Art scheme is as follows:
Bioelectric measurement instrument composition includes: electrode 1, signal conditioning circuit 2, data collecting card 3, device drives 4, panel journey Sequence 5, application program 6, virtual instrument development platform 7, portable PC8, electronic health record 9, bioelectric measurement archives 10.Such as figure Shown in 1, it is characterised in that: electrode 1 is arranged on the bio electricity position that human body is to be measured, and bioelectric small-signal is through signal Modulate circuit 2 amplifies, and is transported on data collecting card 3, device drives 4, panel program 5, application program 6 and virtual instrument Development platform 7 software is arranged on portable PC8, and the operation interface operation developing bioelectric measurement instrument on portable PC8 is whole Instrument, automatically generates bioelectric measurement record simultaneously, automatically analyzes according to measurement result and will convert into case history (9) and bio electricity analysis Measure archives (10).
Use needle electrode or surface electrode.Needle electrode is made up as material, surface electrode silver or corrosion resistant plate of platinum wire Thick 0.2-0.5mm, diameter 8mm disk, equipped with microminiature integrated amplifier, by epoxy encapsulation, there is signal at the disk back side Lead-out wire and power line.Its amplifying circuit is as shown in Figure 2.Skin surface leading electrode it is placed on, under leading electrode during use The locally electrical activity of muscle, is that a kind of non-invasive detection methods is applicable to the change of myoelectricity when guiding Evoked ptential or motion.
The present invention compared with prior art has a following good effect:
1. the operation of bioelectric measurement instrument and measurement result analysis have the virtual interface of virtual instrument to complete on portable computer, make biology Electrical measurement instrument equipment is simple, practical, and reliability is high and the biggest.
2. human body various bio electricity synchro measure carried out by bioelectric measurement instrument, synchronizes to realize brain electricity, myoelectricity, eye is electric (contains on an instrument Retina electricity and nystagmus), stomach electricity measurement.
3. owing to using modularity to have reusable, transplantation, reconfigurable advantage with the design of Hierarchical Design structure, so can Use for other medical apparatus.For hardware, software is simple, it is simple to upgrading, be provided simultaneously with higher precision with very Many functions being difficult on hardware.
4. by Application of Virtual in bioelectric measurement instrument, it is allowed to simple in construction, it is simple to carry.
Accompanying drawing explanation
Fig. 1 bioelectric measurement instrument composition diagram
Fig. 2 surface electrode amplifying circuit
Wherein: electrode 1, signal conditioning circuit 2, data collecting card 3, device drives 4, panel program 5, application program 6, virtual Instrument development platform 7, portable PC8, electronic health record 9, bioelectric measurement archives 10.
Detailed description of the invention
1. bio electricity parameter and the scope of measurement
2. bioelectric measurement electrode
Bioelectric measurement is generally made up of certain treated metallic plate, metal fine needle or wire netting, measures electrode performance excellent Whether good, the measurement result of various bioelectric potential change will be directly affected.
In practice, when generally electrode measurement bioelectric potential being changed, regard as and there occurs on electrode-dielectric interface From ionic conduction to the conversion process of energy of electronic conduction, and the electrical property equivalence of electrode is become by electric capacity and resistance and half The equivalent circuit of cell potential composition.
3. eeg measurement realizes
Eeg measurement, using bipolar lead mode is then by pair of electrodes, measures potential difference between two electrodes, brain electricity Calibration (calibration) voltage of figure is generally with 20,50,100,200,500,1000 several, and multiple tracks is simultaneously entered, by The faintest, generally in magnitude in EEG signals.Its preamplifier due preamplifier technical specification: input Noise≤3 μ V, gain: 500-1000 times, common mode rejection ratio >=80dB, input impedance >=10M Ω.Employing low frequency is handed over Stream coupling, three-stage operational amplifier circuit, low noise field effect transistor, as input stage, use homophase input mode.Preposition Amplifier uses multistage amplifier composition, the high-frequency cut-off frequency of wave filter: 15,35,50,70,100Hz and "Off". Gain control can be divided into overall gain (1/4,1/2,1,2 fourth gear) and branch gain (seven grades, every grade of incremental 6dB) two Plant control mode.
Electroencephalogram is made up of different frequency, different amplitude and different shape brain wave.Electroencephalogram is the life of a kind of randomness Reason signal, it is the clearest and the most definite that its regularity can not show a candle to electrocardiogram, generally amplitude and the frequency content of electroencephalogram is examined as brain electricity Main Basis time disconnected, and frequency content is particularly important.
4. electromyogram is measured and is realized
Using needle electrode and surface electrode, needle electrode is by platinum wire as material, and the tested muscle of sterilized rear insertion draws Lead electromyographic signal.Surface electrode silver or corrosion resistant plate make thick 0.2~0.5mm, diameter 8mm, are placed on skin surface and guide Electrode, for the electrical activity of local muscle under leading electrode, be a kind of non-invasive detection methods be applicable to guide Evoked ptential or The change of myoelectricity during motion.
Electromyographic signal uses the three-stage operational amplifier of homophase input, preamplifier noise≤3 μ V;1,10 sensitivity:, 20,50,100,200,500,1000,2000,5000,10000, error is 10%;02,0.5 stimulus frequency:, 1,2,5,10,20,50Hz, error is 5%;Stimulate pulsewidth: 0.1,0.2,0.5,1ms, error is 10%.
Signal record: two line signals, markers, sensitivity, walking speed etc.
5. an electricity (containing retina electricity and nystagmus electricity) figure is measured and is realized
Electro-oculogram is the potential change record that eye movement causes, and when measuring, pair of electrodes is attached to the both sides of eyes, When the position of eyes is at permanent datum, when the position of eyes is at permanent datum, the current potential of eyes figure is defined as zero, During eye level motion, the just change of the current potential of electro-oculogram.
When retina is stimulated by instantaneous flash, security protection detection electrode on retina inner surface or cornea be placed in forehead Reference electrode, recordable to of short duration current potential order change, the total the most collectively electroretinogram of these potential change.
Electronystagmogram is ocular movement chronognosis film and retina electrogram, and electronystagmogram signal is the faintest, is easily subject to stronger Alternating current and the interference of electromyographic signal, record the nystagmus signal of telecommunication time, use low pass filter remove 15Hz or 20Hz Above interference.
6. clectrogastrogram is measured and is realized
Clectrogastrogram is the electro-gastric signals record of the electrode measurement by being attached on skin of abdomen, owing to electro-gastric signals frequency is the lowest, Only 0.05Hz, usual and respiration interference (0.2~0.4Hz), electrocardiosignal (0.8~1.0Hz), electrode and contact skin Time noise (less than 3Hz), motion artifacts (whole frequency domain) and other noise aliasings, thus result in detection difficult.For This, preamplifier use high input impedance (more than 5M Ω), low noise, low drifting, high cmrr integrated Transport and placing device composition CMRR >=90dB, frequency response: time constant be more than 10S, high-frequency cut-off frequency 100~1000Hz it Between, in order to overcome electrocardio and respiratory wave etc. to disturb, instrument is additionally provided with filtering link.
7. instrument bus and USB interface
The instrument of the present invention uses pcmcia bus, and it is English " PERSONAL COMPUTER MEMORY CARD INTERNATIONAL ASSOCIATION " abbreviation of (PC RAM (random access memory) card international federation), PCMCIA is one more than 300 International Standards Organization of member company and trade community, this is organized into and stands on 1989, it is therefore an objective to set up an integrated circuit state Border standard, improves the interchangeability of mobile computer.This computer desired strength is high, and energy consumption is low, and size is little, and several to this The requirement of bar performance is the highest.PCMCIA promulgated on the basis of 68 pin PC card standards of RAM (random access memory) card in 1991, again Newly formulated two kinds of interface standards of CardBus and ZV in 95 years, made notebook can connect device PCI, as High_speed NIC, Video capture/video conference card, SCSI card etc..
USB interface chip: model: PDIUSBD12.It is a cost and the USB device of function optimization.It is generally used for based on The system of microcontroller and the microcontroller of communication system are in High Speed General parallel interface.It also supports local DMA conversion.Pass through Modular method realizes USB interface, and allows designer to select optimal system microcontroller.Its motility, reduces Development time and risk, and reduce investment.Feature: meet universal serial bus specification 2.0 version (basic rate);Gao Xing The USB interface device of energy, and it is integrated with SIE, FIFO memory, transceiver and manostat;Meet the classification of most devices Specification;Can plug into the high speed parallel interface (2 megabyte/second) of any external microcontroller or microprocessor;Completely self-contained DMA Operation;It is integrated with many structures FIFO memory of 320 bytes;Double buffering scheme adds handling capacity, and simplifies real time data Transmission;Message transmission rate;Message transmission rate: 1Mbytes/s (batch mode), it is achieved 1Mbits/s (synchronous mode); The usb bus that software controls;Programmable clock frequency exports;Internal electrification reset and low-voltage reset circuit;SO28 and TSSOP28 encapsulation mode;Twin voltage operator scheme, 3.3 ± 0.3V or 5V supply voltage scope are 4.0~5.5V;Multiple The bulk transfer of interrupt mode and synchronous transfer.
8. bioelectric measurement instrument operation instruction
Professional nature requirement according to general practitioner, visits process patient in family with the form of visit to the parents of schoolchildren or young workers, and when making house calls, full section cures Take root the Professional knowledge according to oneself and clinical experience, in conjunction with the concrete condition of diagnosis patient, see Fig. 1, one will be selected and be suitable for Patient exports the electrode in 1 and is arranged on the suitable position of patient body, by the Virtual Instrument on screen of portable computer Control and operate whole instrument, automatically analyze simultaneously and generate bioelectric measurement record, automatically will convert into disease according to diagnostic result Go through, check that result analyzes archives with bioelectric measurement.

Claims (5)

1. a bioelectric measurement instrument for general practitioner, its composition includes: electrode (1), signal conditioning circuit (2), data acquisition Card (3), device drives (4), panel program (5), application program (6), virtual instrument development platform (7), portable PC (8), Electronic health record (9), bioelectric measurement archives (10), it is characterised in that: electrode (1) is arranged on the bio electricity that human body is to be measured Position, bioelectric small-signal, through signal conditioning circuit (2) amplification, is transported on data collecting card (3), device drives (4), Panel program (5), application program (6) and virtual instrument development platform (7) software are arranged on portable PC (8), and portable The upper whole instrument of operation interface operation developing bioelectric measurement instrument of PC (8), automatically generates bioelectric measurement record, root simultaneously Automatically analyze and will convert into case history (9) according to measurement result and analyze archives (10) with bioelectric measurement.
Bioelectric measurement instrument the most according to claim 1, it is characterised in that: electrode (1) uses needle electrode or surface electrode.
Bioelectric measurement instrument the most according to claim 2, it is characterised in that: needle electrode by platinum wire as material.
Bioelectric measurement instrument the most according to claim 2, it is characterised in that: surface electrode silver or corrosion resistant plate make thickness 0.2-0.5mm, diameter 8mm disk, equipped with microminiature integrated amplifier, by epoxy encapsulation, there is signal at the disk back side Lead-out wire and power line.
5. according to claim 1, it is characterised in that: the agent structure of virtual instrument uses pcmcia bus.
CN201510004676.2A 2015-01-04 2015-01-04 Bioelectric measurement apparatus for general medical practitioners Pending CN105877733A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106473737A (en) * 2016-11-24 2017-03-08 张珊珊 A kind of measuring system based on the sEMG muscle and deep signal of telecommunication
CN108634948A (en) * 2018-05-11 2018-10-12 南京宽诚科技有限公司 A kind of detection method, device, detection device and the storage medium of stomach and intestine electric signal
CN108742590A (en) * 2018-04-08 2018-11-06 南京宽诚科技有限公司 A kind of acquisition method, device, collecting device and the storage medium of stomach and intestine electric signal

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CN102512159A (en) * 2011-12-08 2012-06-27 西安交通大学 Portable wireless electroencephalogram acquisition device
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CN87102381A (en) * 1987-03-30 1988-10-12 创建基立有限公司 Biological signal detection processing unit and method
WO1993007804A1 (en) * 1991-10-25 1993-04-29 Aspect Medical Systems, Inc. Cerebral biopotential analysis system and method
CN2227943Y (en) * 1995-06-29 1996-05-29 河南省人民医院 Single-path electroencephalograph
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106473737A (en) * 2016-11-24 2017-03-08 张珊珊 A kind of measuring system based on the sEMG muscle and deep signal of telecommunication
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CN108742590A (en) * 2018-04-08 2018-11-06 南京宽诚科技有限公司 A kind of acquisition method, device, collecting device and the storage medium of stomach and intestine electric signal
CN108634948A (en) * 2018-05-11 2018-10-12 南京宽诚科技有限公司 A kind of detection method, device, detection device and the storage medium of stomach and intestine electric signal

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