CN105866034A

CN105866034A - Light absorption information detection apparatus and method of liquid phase sample and gaseous ions thereof

Info

Publication number: CN105866034A
Application number: CN201610193093.3A
Authority: CN
Inventors: 董晓峰; 陈焕文; 肖赛金
Original assignee: East China Institute of Technology
Current assignee: East China Institute of Technology
Priority date: 2016-03-30
Filing date: 2016-03-30
Publication date: 2016-08-17
Anticipated expiration: 2036-03-30
Also published as: CN105866034B

Abstract

The invention provides a light absorption information detection apparatus and a method of a liquid phase sample and gaseous ions thereof. The apparatus is a sealed chamber structure, and comprises a light source module, a detection module, a manual adjustment module, a spray ion source, an electric translation module and a cavity module used for fixing all parts, the main body of the cavity module is a chamber structure provided with a plurality of through holes, and the spray ion source is arranged at the upper portion of the cavity module, goes through the upper portion through hole and stretches into a chamber; and the light source module and the detection module are respectively fixedly arranged in through holes of the two opposite side surfaces of the cavity module, and the light path centers of the light source module and the detection module are positioned in a same horizontal plane, and are coaxial. The apparatus has the advantages of compact layout, low cost, agile configuration, convenient use and high stability, and the detection method realized by adopting the apparatus can be used to detect the light absorption information of gaseous ions generated through a normal pressure ESI technology of the liquid phase sample, and also can realize continuous detection of sample ions from a liquid state to a gaseous state.

Description

A kind of liquid phase sample and gaseous ion light thereof absorb information detector and method

Technical field

The invention belongs to analysis technical field, relate to liquid phase sample and gaseous ion light absorbs information detector and side Method, the light being specifically related under a kind of gaseous ion state that can be not only used for liquid phase sample absorbs infomation detection, can be used for again Conventional liquid phase sample light absorbs the device and method of infomation detection.

Background technology

For liquid phase substance light absorb information detection in, easily by solvent microenvironment such as temperature, polarity, acidity, glue The impact of the factors such as degree, therefore the light of liquid phase substance absorbs the material optical information obtained in infomation detection generally and material Essential optical property there is certain deviation.Although this has been recognized by scientific worker, not find suitable always Method detect desolvated liquid phase substance light absorb information.

Nearly ten years, the light of what gas phase ion spectrometry learned a skill develop into desolvation liquid phase substance absorbs infomation detection and carries Having supplied possible, gas phase light absorbs infomation detection and is thus paid close attention to by more and more scientific workers.Wherein, electron spray Ionization (ElectroSpray Ionization, ESI) technology is the most frequently used gaseous ion generation technique, from ESI In the space of taylor cone certain distance, most of ion that ESI is generated all becomes the gaseous ion not having solvent to surround. Therefore, under these conditions, the radiative property of analyte is not affected by solvent, closer to actual value.Mesh Before, Konstantin Chingin, Huanwen Chen, Gerardo Gamez et al. are to super-pressure, high vacuum ESI The optical information of gaseous ion that technology generates carried out detection research [Konstantin Chingin, Huanwen Chen, Gerardo Gamez,et al.Exploring Fluorescence and Fragmentation of Ions Produced by Electrospray Ionization in Ultrahigh Vacuum[J].Am Soc Mass Spectrom,2009, 20:1731～1738], device used is complicated, expensive and is limited by super-pressure, high vacuum, and due to superelevation Gaseous ion prepared by voltage ESI technology is captured, excites and detects in high vacuum ion trap, temperature in ion trap, The capture factor such as energy, exciting light energy all produces impact in various degree to the optical information of gaseous ion.

Different from super-pressure ESI, normal pressure ESI technology produces gaseous ion in atmospheric environment, and exciting light energy is at air Environment is cooled rapidly, the optical information of gaseous ion is affected less, and the relatively low temperature of atmospheric environment also has Being beneficial to stablizing of gaseous ion, therefore normal pressure ESI technology is more suitable for detecting the light absorption information of gaseous ion.

Gaseous ion is in flow regime after generating, and how to catch light while gaseous ion generates absorbing information is gas Phase ionic light absorbs the Major Difficulties of infomation detection, and the gaseous ion being in atmospheric pressure environment is entered by Konstantin etc. Go research, but this device is by manually having built, there is poor air-tightness, poor stability, configuration dumb etc. no Enough, and the light of gaseous ion can only be absorbed and detect by this device, and cannot detect light simultaneously and absorb information, makes By narrow range, the device of the light absorption infomation detection being currently used for the gaseous ion that normal pressure ESI technology generates is the most rarely found, This to a certain degree on limit gaseous ion light absorb information detection, study and apply.

Summary of the invention

In order to solve the problems referred to above, the present invention provides a kind of compact in design, with low cost, and flexible configuration is easy to use, Liquid phase sample and gaseous ion light thereof that stability is high absorb information detector, and it can be used for detecting liquid phase sample and passes through The light of the gaseous ion that normal pressure ESI technology generates absorbs information, and also can realize sample ions from liquid phase is the mistake of gas phase The continuous detection of journey, the most also can realize the conventional liquid phase sample light of detection and absorb information.

The above-mentioned purpose of the present invention is realized by techniques below scheme:

The gaseous ion light of a kind of liquid phase sample absorbs information detector, including light source module, detection module, spraying Ion gun and for fixing the cavity module of above-mentioned each parts, wherein:

The main body of cavity module is to be provided with the chamber structure of multiple through hole, and described esi ion source is arranged on cavity module Top is also stretched in chamber by upper through-hole；

Light source module is individually fixed in the through hole of the relative two sides of cavity module, light source module and inspection with detection module The light path surveying module is centrally located in same level, and the light path central coaxial of light source module and detection module.

The gaseous ion light of above-mentioned liquid phase sample absorbs information detector and also includes manual adjustment module；Described manual tune Joint module includes height adjustment mechanism and angle adjusting mechanism, and wherein, height adjustment mechanism is set in cavity movably In the described upper through-hole of module, angle adjusting mechanism is fixed on the upper end of height adjustment mechanism, the two be respectively equipped with The elongated hole that the chamber of cavity module is connected, esi ion source passes height adjustment mechanism, the elongated hole of angle adjusting mechanism Stretch in the chamber of cavity module.

The gaseous ion light of above-mentioned liquid phase sample absorbs in information detector, and described height adjustment mechanism includes highly adjusting Joint ion source(-)holder, height regulation ion source(-)holder is the cylinder that top is provided with end cap, and cylinder is set in the described of cavity module In upper through-hole, the size of end cap is more than the diameter of cylinder, and the middle part of end cap offers described elongated hole；Angular adjustment machine Structure includes angular adjustment ion source(-)holder, and it is fixed on the end cap of height regulation ion source(-)holder by pilot hole, and middle part sets There are the described elongated hole corresponding with height regulation ion gun seat positions and dimensions, the dual-side on described plate body length direction The most integrally being extended with two arc-shaped guide rails, the upper limb of this guide rail is respectively provided with and outward extends flange；

Described angle adjusting mechanism also includes front-slider, ion gun fixed mount, rear slider, slider locking screw head and ion Source locking screw head:

Ion gun fixed mount bottom surface is in the arc matched with described rail shapes, and middle part is provided with and is connected with described elongated hole Installing hole, in installing hole insert esi ion source；

Front-slider and rear slider are installed on the flange of two arc-shaped guide rails the most respectively, and ion gun fixed mount is by assembling Hole is fixed between front-slider and rear slider, and is positioned on described two arc-shaped guide rails；

Described rear slider is fixed on described arc-shaped guide rail in order to lock ion gun fixed mount by slider locking screw head；Ion Esi ion source is fixed in described installing hole in order to lock esi ion source by source locking screw head.

The gaseous ion light of above-mentioned liquid phase sample absorbs in information detector, and the top of described cavity module is additionally provided with folder Tight mechanism, it is double-deck plate body, is provided with upper through-hole and chamber with described cavity module and is connected in the middle part of described plate body Through hole, a top plate part is integrally connected with lower plywood, and another part separates with lower plywood, and at partitioning portion A certain position be broken as the first clamping part and the second clamping part, the first clamping part and the second clamping part and be provided with regulation bolt, The first clamping part and the second clamping part generation elastic deformation is made, the hand installed in locking or discharging through hole by regulation bolt Dynamic adjustment module.

The gaseous ion light of above-mentioned liquid phase sample absorbs information detector and also includes electric translation module；Described electronic flat Shifting formwork block is arranged on the side of cavity module, and is connected with manual adjustment module, it is possible to drive manual adjustment module with Esi ion source moves up and down together；Described electric translation module includes linking arm, electric platforms seat, screw support axle Hold, screw rod, feeding slide unit, brake type stepper motor and two polished rods；Wherein:

Linking arm is for being connected to manual adjustment module by electric translation module；

Electric platforms seat is strip plate body, and it is fixed on the side of cavity module, and its upper side is provided with the three of separation Individual side wall, described side wall is respectively provided with circular hole, and screw rod one end is mounted on the screw support axle in the side wall circular hole of one end In holding, the other end is installed on the output shaft of brake type stepper motor through another two side wall；

Two polished rods are positioned at the both sides of screw rod, and are fixed between both walls, and feeding slide unit is set on screw rod and polished rod, And fixing with linking arm be connected.

A kind of liquid phase sample light absorbs information detector, and it is annular seal space cell structure, including light source module, detection mould Block, for fixing the cavity module of above-mentioned each parts, the cuvette being placed in cavity module and for sealing described chamber The capping of module, wherein:

The main body of cavity module is to be provided with the cavity body structure of through hole, and light source module and detection module are individually fixed in cavity mould The through hole of the side of block, the light path of two modules is centrally located in same level, and light source module and detection module Light Lu Zhizheng vertical；

Cuvette equipped with sample solution is positioned in the chamber of cavity module, and is positioned at described light source module and detection module Light Lu Zhizheng；

Described capping is the cylinder that top is provided with circular end cap, and the diameter of circular end cap is more than the diameter of cylinder, and cylinder is put In the through hole on cavity module top.

The bottom of described cavity module is provided with groove, is provided with the screw for connected drainage pipe joint in the middle part of groove；Equipped with The cuvette of sample solution is positioned in the groove at a cuvette deck top, and the bottom of cuvette deck is placed in cavity module In the groove of bottom.

The gaseous ion light of above-mentioned liquid phase sample absorbs information detector or liquid phase sample light absorbs information detector In, the source path of described light source module is sequentially provided with sealing plate, LED light source, filter and planoconvex spotlight from outside to inside, Wherein, being positioned at outermost end for isolating the sealing plate of ambient, LED light source is installed on a LED and installs in set；Filter, Planoconvex spotlight is installed in a lens sleeve, and lens sleeve is installed in the inner core of a light lens seat, and described light source is saturating Microscope base one end connects on the one side of cavity module, and the other end and LED install set airtight connection, and LED installs another of set Hold be connected fixing with sealing plate；One lens stage clip and lens sleeve are installed in the inner core of described light lens seat successively； Described LED install set is connected with adjustable thread with light lens seat, by control be screwed into LED installation overlap the degree of depth realize right Planoconvex spotlight is finely adjusted with the distance of cavity module.

The gaseous ion light of above-mentioned liquid phase sample absorbs information detector or liquid phase sample light absorbs information detector In, described light source module also includes slit base, and described slit base is the framework of hollow, and this framework is the most successively Being provided with microdrum, movable plate, wear-resistant sleeve, polished rod, fixed plate, wherein, microdrum bottom is inserted in slit base In the through hole of side, the end face of movable plate is withstood in its lower end；Fixed plate is that two is block-shaped similar and cooperation makes with movable plate Trapezoidal plate, the inclined-plane of two boards is relatively and the same side, drift angle limit on inclined-plane is placed and formed slit, and polished rod sequentially passes through Wear-resistant sleeve and a slit stage clip, and be fixed between fixed plate and movable plate by pilot hole；By rotating microdrum energy Enough making movable plate move up and down, the slit light belt formed between movable plate and fixed plate is adjustable.

The gaseous ion light of above-mentioned liquid phase sample absorbs information detector or liquid phase sample light absorbs information detector In, described detection module is sequentially provided with detection lens mount, filter, planoconvex spotlight, optical fiber in its light path received Set and optical fiber screw head, wherein, filter, planoconvex spotlight are installed in a lens sleeve；Lens sleeve is installed on detection thoroughly In microscope base, detection lens mount one end is installed on the one side of cavity module, the other end and the optical fiber equipped with optical fiber screw head Set airtight connection；One lens stage clip and lens sleeve are installed in the inner core of described detection lens mount successively；Described detection Lens mount is connected with adjustable thread with optical fiber set, and the degree of depth being screwed into optical fiber set by control realizes entering detection module light path Row fine setting.

The gaseous ion light of above-mentioned liquid phase sample absorbs information detector or liquid phase sample light absorbs information detector In, the bottom of described cavity module is provided with base, and the corner of base has been respectively fixedly connected with supporting leg, supporting leg lower end Connect the spike having for supporting cavity module；The bottom surface of described spike is cone, and upper end is provided with screw head, spiral shell Head is connected with the screwed hole of supporting leg lower end, and the screw head of regulation spike is screwed into the degree of depth to regulate the levelness of cavity module.

The present invention also provides for a kind of liquid phase sample and gaseous ion light absorbs information detecting method, and the method uses this Bright liquid phase sample and gaseous ion light thereof absorb information detector and detect, and realize by the following technical solutions:

The gaseous ion light of a kind of liquid phase sample absorbs information detecting method, uses the gaseous ion light of above-mentioned liquid phase sample Absorb information detector to detect, comprise the following steps:

(1) described light source module, detection module, manual adjustment module, esi ion source and electric translation module are filled It is fitted in cavity module, and regulates a spike of cavity module, make described device be horizontal；

(2) connection have the optical fiber of optical signal detecting equipment be connected in the optical fiber screw head of detection module；

(3) at the sample channel of esi ion source, connect an injector, injector be passed through sample to sample channel molten Liquid, is passed through gas at gas passage；The stainless steel needle tubing being provided with in injector front end is accessed high-voltage conducting wires end and connects High pressure；

(4) open LED light source or the laser of light source module, and open optical signal detecting equipment and detect；

(5) by the electric translation ionogenic height of module adjustable spraying, changed from liquid phase to gas phase in sample ions Cheng Zhong, the light of detection sample ions absorbs information, to obtain the relation of esi ion source height parameter and testing result.

A kind of liquid phase sample light absorbs information detecting method, uses above-mentioned liquid phase sample light to absorb information detector and carries out Detection, comprises the following steps:

(1) light source module, detection module are assembled in cavity module, a spike of regulation cavity module, make described Device is horizontal；

(2) groove of the bottom of cavity module is put into the cuvette equipped with fluid sample after being assembled by cuvette deck In, and with covering the described upper through-hole of closed cavity module；

(3) connection have the optical fiber of optical signal detecting equipment be connected in the optical fiber screw head of detection module；

(4) open LED light source or the laser of light source module, and open described optical signal detecting equipment and carry out liquid phase sample The light of product absorbs infomation detection.

The present invention uses above technical scheme, can realize techniques below effect: (1) applied range of the present invention, permissible Information is absorbed, it may also be used for the light of detection conventional liquid phase sample absorbs letter for detecting the light of the gaseous ion of liquid phase sample Breath；(2) present invention can pass through the ionogenic angle of adjustable spraying and electrospray ionization source height, it is achieved in certain limit The regulation of esi ion source space position parameter, and then realize sample ions light suction from liquid phase to gas phase change procedure The continuous of breath of collecting mail detects；(3) present invention can realize the manual regulation of esi ion source angle, it is possible to passes through program Control Driving Stepping Motor and realize being automatically adjusted of electrospray ionization source height, convenient use；(4) present invention uses module Change design, it is simple to block combiner and extension, flexibility is strong；(5) LED light source of the light source module of the present invention can use The laser of high-energy-density, it would however also be possible to employ common low-power consumption LED light source, is applicable to different application scenarios；(6) Compact in design of the present invention, each main member technique is simple, and related accessory is the standard component of easily buying, thus cost is relatively Low.

Accompanying drawing explanation

Fig. 1 is the three-dimensional structure diagram of apparatus of the present invention embodiment；

Fig. 2 is the exploded view of each building block in Fig. 1；

Fig. 3 is the exploded view of cavity module；

Fig. 4 is the exploded view of light source module；

Fig. 5 is the exploded view of detection module；

Fig. 6 is the exploded view of manual adjustment module；

Fig. 7 is the ionogenic stereogram of normal pressure spray；

Fig. 8 is the stereogram of electric translation module and axial cut away view thereof；

Fig. 9 is stereogram and the partial cross sectional views thereof of the clamp system of cavity module；

Figure 10 is the stereogram of the main body different angles of cavity module；

Figure 11 is the stereogram of the base of cavity module；

Figure 12 is the stereogram of a spike of cavity module；

Figure 13 is the stereogram of the discharging tube joint of cavity module；

Figure 14 is the stereogram of the cuvette deck of cavity module；

Figure 15 is the stereogram of the sealing plate of light source module；

Figure 16 is the stereogram of the LED light source of light source module；

Figure 17 is that the LED of light source module installs the perspective cut away view overlapped；

Figure 18 is the perspective cut away view of the lens sleeve of light source module；

Figure 19 is the perspective cut away view of the light lens seat of light source module；

Figure 20 is the stereogram of the slit base of light source module；

Figure 21 is the perspective cut away view of the fixed plate of light source module；

Figure 22 is the stereogram of the movable plate of light source module；

Figure 23 is the stereogram of the microdrum of light source module；

Figure 24 is the three-dimensional structure diagram of shrouding；

Figure 25 is the perspective cut away view of the detection lens mount of detection module；

Figure 26 is the perspective cut away view of the optical fiber set of detection module；

Figure 27 is the stereogram of the optical fiber screw head of detection module；

Figure 28 is the stereogram of the height regulation ion source(-)holder of manual adjustment module；

Figure 29 is the stereogram of the angular adjustment ion source(-)holder different angles of manual adjustment module；

Figure 30 is the stereogram of the front-slider of manual adjustment module；

Figure 31 is the stereogram of the ion gun fixed mount different angles of manual adjustment module；

Figure 32 is the stereogram of the rear slider different angles of manual adjustment module；

Figure 33 is the stereogram of the electric platforms seat different angles of electric translation module；

Figure 34 is the stereogram of the screw rod of electric translation module；

Figure 35 is stereogram and the cut away view thereof of the feeding slide unit of electric translation module；

Figure 36 is the stereogram of the nut of electric translation module；

Figure 37 is the stereogram of the bearing (ball) cover of electric translation module.

In figure, reference is expressed as:

1: cavity module；10: clamp system, 100: screw, 101: the first clamping parts, 102: the second clamping parts, 103: counter sink, 104: screwed hole；11: chamber body, 112,115: screwed hole, 113,116: through hole, 114,118,119: screw；12: base, 120,123: counter sink, 121: groove, 122: screw；13: Supporting leg；14: a spike, 140: screw head, 141: bottom surface；15: discharging tube joint, 150: screw head, 151: Hexagonal (hexagon)nut, 152: reversely draw-in groove；16: cuvette deck, 160: bottom, 161: top slot；17: cuvette；

2: light source module, 20: sealing plate, 200: counter sink, 201: through hole；21:LED light source, 210:LED Lamp bead, 211: through hole；22:LED installs set, and 220: screw head, 221,222: screwed hole；23: interior bung flange； 24；Dottle pin；25: filter；26: planoconvex spotlight；27: lens sleeve, 270: medial surface, 271: screw；28: Lens stage clip；29: light lens seat, 290: counter sink, 291: pin-and-hole, 292: screw, 293: medial surface； 30: slit base, 300,303: counter sink, 301: pin-and-hole, 302: screwed hole, 303: counter sink, 304: logical Hole, 305: screwed hole；31: fixed plate, 310: hole, 311: drift angle limit, 312: screwed hole；32: polished rod； 33: slit stage clip；34: wear-resistant sleeve；35: movable plate, 350: hole, 351: drift angle limit；36: microdrum, 361: Outer cylinder, 362: spherical surface body；37: shrouding, 370: counter sink；

4: detection module；40: detection lens mount, 400: periphery, 401: counter sink, 402: inner headed face, 403: Screw；41: lens stage clip；42: interior bung flange；43: dottle pin；44: filter；45: planoconvex spotlight；46: lens Sleeve；47: optical fiber set, 470: screw head, 471: screw；48: optical fiber screw head, 480,482: screw head, 481: Nut；

5: manual adjustment module；50: height regulation ion source(-)holder, 500: cylinder, 501: circular end cap, 502: Counter sink, 503: pin-and-hole, 504: screw, 505: altitude scale；51: angular adjustment ion source(-)holder, 510: spiral shell Hole, 511: pin-and-hole, 512: arc-shaped guide rail, 513: angle index；52: front-slider, 520,541: upper cambered surface, 522: angle index instruction line, 523: cone head hole；53: ion gun fixed mount, 530: through hole, 531,533: spiral shell Hole, 532: side screw；54: rear slider, 521,540: lower camber side, 542: cone head hole, 543: screw；55: Slider locking screw head；56: ion gun locking screw head；

6: esi ion source, 60: gas passage, 61: sample channel, 62: matrix；

7: electric translation module；70: linking arm；71: clamp nut；72: electric platforms seat, 720,723: circle Hole, 721: side opening, 722: screw, 724: screwed hole, 725: counter sink；73: screw support bearings；74: Screw rod；75: feeding slide unit, 750: side opening, 753: through hole, 754: screw, 755: screwed hole；76: nut, 760: cylinder, 761: counter sink；77: bearing (ball) cover, 770: screw, 771: screwed hole；78: elastic connecting shaft Device；79: brake type stepper motor；710: polished rod.

Detailed description of the invention

Below in conjunction with the drawings and specific embodiments, liquid phase sample and gaseous ion light thereof to the present invention absorb infomation detection Device and method is described in detail, and wherein, the device of 26S Proteasome Structure and Function identical in accompanying drawing is with identical accompanying drawing mark Note marks, and accompanying drawing is only intended to help explain the present invention, does not represent limitation of the scope of the invention.

Fig. 1 is the three-dimensional structure diagram of apparatus of the present invention embodiment, and Fig. 2 shows the decomposition texture of each comprising modules in Fig. 1. As depicted in figs. 1 and 2, apparatus of the present invention are the sealing structure with chamber, including light source module 2, detection module 4, Manual adjustment module 5, esi ion source 6, electric translation module 7 and be used for fixing above-mentioned each parts and chamber being provided Cavity module 1, the main body 11 of cavity module 1 is the chamber structure being provided with through hole, the through hole of its relative two sides Being respectively mounted light source module 2 and detection module 4, the light path of two modules is centrally located in same level, and light source die Block 2 and the light path central coaxial of detection module 4；Electric translation module 7 is arranged on the side not setting through hole of cavity module 1 On face, manual adjustment module 5 is arranged at the upper through-hole of cavity module 1, and one or more esi ion sources 6 are plugged in The upper end of manual adjustment module 5 also extend into the chamber of cavity module 1, and electric translation module 7 with manually regulate mould The height adjustment mechanism of block 5 is connected so that when electric translation module 7 works, and can drive manual adjustment module 5 and spraying Ion gun 6 moves up and down together.

Cavity module

Fig. 3 shows the decomposition texture of cavity module 1, and Fig. 9 to Figure 14 respectively illustrates each building block of cavity module 1 Structure.As indicated at 3, cavity module 1 includes clamp system 10, chamber body 11, base 12, supporting leg 13, props up Spike 14, discharging tube joint 15, cuvette deck 16, cuvette 17 and capping, wherein:

The main body 11 of cavity module 1 is the chamber structure being provided with through hole, and its through hole, upper end is fixed with centre and is provided with centre bore Clamp system 10, it is double-deck plate body structure, and a top plate part is connected with lower plywood one, another part and under Laminate separates, and is broken as the first clamping part 101 and the second clamping part 102 in a certain position of partitioning portion, Two clamping parts 102 are provided with counter sink 103, are provided with screwed hole 104, the first clamping part 101 on the first clamping part 101 It is provided with regulation bolt with the second clamping part 102, when this regulation bolt is screwed in counter sink 103 and screwed hole 104, first There is elastic deformation in clamping part 101 and the second clamping part 102, thus locks the part (hand in clamp system 10 centre bore Height regulation ion source(-)holder 50 (seeing Fig. 6) of dynamic adjustment module 5), when unclamping dormant bolt, discharge clamp system Part in 10 centre bores；The corner of clamp system 10 is by its screw 100 and the screw 114 of chamber body 11 and main body 11 fixing connections.

As shown in Figure 10, in the side of the main body 11 of cavity module 1, wherein relative to the middle part of two sides be respectively provided with logical Hole 113 and 116, through hole 113 be formed around screwed hole 112, be used for detection module 4 is installed；The side at through hole 116 place Face is provided with screwed hole 119, is used for installing light source module 2；The one side not offering through hole is provided with screw 118, is used for pacifying Dress electric translation module 7.

As shown in Figure 11, Figure 12 and Figure 13, base 12 is the plate body that the base of the main body 11 with cavity module 1 matches, Position corresponding with the screwed hole 115 on main body 11 base on base 12 is provided with counter sink 120, and it is heavy to be connected by screw Head bore 120 and screwed hole 115 are connected fixing with the main body 11 of cavity module 1 for base 12；It is heavy that the corner of base 12 is respectively provided with Head bore 123, is connected by screw counter sink 123 and the screwed hole 130 of supporting leg 13 upper end, by base 12 respectively with four Supporting leg 13 is fixing to be connected；The screw head 140 of a spike 14 with conical bottom surface 141 is screwed into the spiral shell of supporting leg 13 lower end In pit 131, bottom surface 141 is placed on working face, saves whole chamber by the depth adjustable that is screwed into of four spikes 14 of regulation The levelness of module 1；The middle part of base 12 is provided with groove 121, and the middle part of groove 121 is provided with screw 122, and it is used for Connected drainage pipe joint 15, by screwing the hexagonal (hexagon)nut 151 of discharging tube joint 15, is screwed into screw 122 by screw head 150 In, it is connected fixing with base 12 for discharging tube joint 15；Plastic pipe can be socketed at the reverse draw-in groove 152 of discharging tube joint 15, For discharging waste liquid.

When carrying out conventional liquid phase detection, the bottom that will be equipped with the cuvette 17 of sample solution is needed to be placed in cuvette deck In the top slot 161 of 16, the bottom 160 of cuvette deck 16 is placed in the groove 121 of base 12.Now also need to one The upper through-hole of cavity module 1 is sealed by capping, and this capping is identical with height regulation ion source(-)holder 50 (see Figure 28) shape, The difference of the two is, the circular end cap of capping is a complete plate, and elongated hole is not offered at middle part.

Light source module

Fig. 4 shows the decomposition texture of light source module 2, and Figure 15 to Figure 24 shows each building block of light source module 2 Structure.As shown in Figure 4, light source module 2 include sealing plate 20, LED light source 21, LED install set 22, interior bung flange 23, Dottle pin 24, filter 25, planoconvex spotlight 26, lens sleeve 27, lens stage clip 28, light lens seat 29, slit base 30, Fixed plate 31, polished rod 32, slit stage clip 33, wear-resistant sleeve 34, movable plate 35 and microdrum 36, wherein:

As shown in figures 4 and 18, lens sleeve 27 is the cylinder of horizontal opening, and side is provided with annular inboard face 270, separately Side is provided with screw 271；Dottle pin 24 has two, dottle pin 24, filter 25, planoconvex spotlight 26, dottle pin 24 is placed in successively In the endoporus of lens sleeve 27, interior bung flange 23 is screwed in the screw 271 of lens sleeve 27, makes above-mentioned parts hold out against The medial surface 270 of mirror sleeve cylinder 27.

As shown in figure 19, light lens seat 29 includes that middle part is provided with the plate of through hole and around this through hole towards side integration The cylinder extended, this plate is provided with the counter sink 290 for connecting slit base 30 and the pin-and-hole 291 for location；Should Cylinder embeds in plate, does not penetrate this plate, and its diameter is more than the diameter of through hole, this cylinder bottom surface and plate Through hole forms annular inboard face 293, and cylinder end is provided with screw 292, by lens stage clip 28 and the lens sleeve assembled In 27 cylinders being sequentially placed into light lens seat 29.

As shown in figure 18, it is cylindrical cavity that LED installs set 22, and its one end is provided with screw head 220, by this screw head 220 In the screw 292 of the cylinder end being screwed into light lens seat 29, by tightening LED, set 22 is installed, compresses lens stage clip 28, Make its inner face hold out against medial surface 293, LED can be screwed into by control and the degree of depth of set 22 is installed to realize planoconvex spotlight 26 It is finely adjusted with the distance of cavity module 1；It is provided with prominent anchor ring in the cavity of the other end that LED installs set 22, This anchor ring is provided with screwed hole 221, is used for connecting LED light source 21, and this end lateral surface is provided with screwed hole 222, for even Connect sealing plate 20.

As shown in figure 15, sealing plate 20 is positioned at the outermost end of light source module, is used for isolating ambient, as shown in figure 15, Sealing plate 20 surrounding is evenly distributed with counter sink 200, is provided with through hole 201 in the middle part of it, and this through hole 201 is used for introducing LED light The power line in source 21, can also be used for the introduction passage of laser when using laser；It is connected by screw counter sink 200 and LED The screwed hole 222 of set 22 is installed, is connected fixing with LED installation set 22 for sealing plate 20；By the lamp bead 210 of LED light source 21 Putting into LED and install the cavity of set 22, the through hole 211 being connected by screw LED light source 21 installs the screw thread overlapping 22 with LED Hole 221, installs LED light source 21 with LED and overlaps fixing connection.

As shown in figure 20, the slit base 30 of light source module 2 is the framework of hollow, and its upper side is provided with for installing microdrum The through hole 304 of 36, lower inside surface is provided with counter sink 303, is used for connecting fixed plate 31, and frame edge is provided with countersunk head Hole 300, this counter sink 300 is connected, by light source die with the screwed hole on the side of the main body 11 of the cavity module 1 installed Block is installed in cavity module 1, frame edge be additionally provided with pin-and-hole 291 with light lens seat 29 with the use of pin-and-hole 301, be used for positioning, and frame edge be additionally provided with counter sink 290 with light lens seat 29 with the use of screwed hole 302, for being connected fixing with slit base 30 for light lens seat 29.

As shown in Figure 21 to Figure 23, wear-resistant sleeve 34 is circular sleeve, and fixed plate 31 and movable plate 35 are two block-shaped similar And with the use of trapezoidal plate, the inclined-plane of two boards relatively and the same side, drift angle limit 311,351 on inclined-plane place formed narrow Seam, the side, inclined-plane of fixed plate 31 is provided with hole 310, and this Kong Wei penetrates fixed plate, for being embedded in the lower end of polished rod 32, and tiltedly The relative side opening in side, face is provided with screwed hole 312, for connecting the counter sink 303 of slit base 30；The inclined-plane of movable plate 35 On offer through hole 350, be used for being embedded in wear-resistant sleeve 34；The upper end of two polished rods 32 is enclosed within wear-resisting in the way of matched in clearance In the endoporus of set 34, can relatively slide therebetween；The periphery of wear-resistant sleeve 34 is embedded into shifting in an interference fit In the hole 350 of dynamic plate 35, slit stage clip 33 is enclosed within the outside of polished rod 32, and wear-resistant sleeve 34 is withstood in its upper end, and lower end is withstood solid Determine plate 31, under the effect of slit stage clip 33, movable plate 35 can together with wear-resistant sleeve 34 sliding axially along polished rod 32.

As shown in figure 23, microdrum 36 is stepped cylinder, and its bottom is inserted on the upper side of slit base 30 In through hole 304, the end that diameter is little is spherical surface body 362, and it withstands the end face of movable plate 35, on the upside of slit base and through hole 304 screwed holes 305 being positioned on same vertical plane are for fixing microdrum 36, when the outer cylinder 361 rotating microdrum 36 Time, movable plate 35 moves up and down, at the drift angle of movable plate 35 under the common effect of spherical surface body 362 and slit stage clip 33 Form a certain size slit between the drift angle limit 311 of limit 351 and fixed plate 31, thus in light path, obtain a width Adjustable light belt, after adjusting, is screwed into holding screw in the screwed hole 305 of slit base 30 and is fixed by microdrum.

As shown in figure 24, shrouding 37 is the plate body being provided with counter sink 370, when not using light source module 2, and can be by envelope Plate 37 is replaced, by the screwed hole 119 on the counter sink 370 main body 11 side with cavity module 1, by cavity module Through hole 116 on main body 11 side of 1 seals, and isolates ambient.

Detection module

Fig. 5 shows the decomposition texture of detection module 4, and Figure 25, Figure 26 and Figure 27 respectively illustrate each group of detection module 4 Become the structure of parts.As it is shown in figure 5, detection module 4 include detect lens mount 40, lens stage clip 41, interior bung flange 42, Dottle pin 43, filter 44, planoconvex spotlight 45, lens sleeve 46, optical fiber set 47 and optical fiber screw head 48, wherein:

As shown in figure 25, the detection lens mount 40 of detection module 4 is circular sleeve structure, and one end inside contracts formation annular inner circle Face 402, the cartridge exterior near annular inner headed face forms prominent anchor ring around sleeve, and on this prominent anchor ring, separation is provided with many Individual counter sink 401, forms periphery 400 near the end of this prominent anchor ring, and the other end is screw 403.

As shown in Figure 26 and Figure 27, optical fiber set 47 is the two-stage circular sleeve of one end open, and openend is provided with screw head 470, Screw 471 it is provided with in the middle part of other end side；Optical fiber screw head 48 is hollow structure, is respectively arranged at two ends with screw head 480 and 482, Centre is provided with nut 481, and screw head 480 is screwed in the screw 471 of optical fiber set 47, optical fiber screw head 48 is connected with optical fiber set 47, Screw head 482 can be used for connecting follow-up optical information detection equipment.

In interior bung flange 42, dottle pin 43, filter 44, planoconvex spotlight 45, the mounting means of lens sleeve 46 and light source module Part mounting means of the same name the same, the focal length parameter of the planoconvex spotlight 45 of the two is the most different；Successively by lens Stage clip 41 and the lens sleeve 46 being completed are placed in the screw 403 of detection lens mount 40, a termination of lens stage clip 41 Touching the inner headed face 402 of detection lens mount 40, screw head 470 is screwed into detection lens by the optical fiber set 47 being provided with optical fiber screw head 48 In the screw 403 of seat 40, the lens sleeve 46 being completed, can be with water under the effect that lens stage clip 41 and optical fiber overlap 47 Translation is dynamic, and the degree of depth being screwed into by controlling optical fiber set 47 can realize the fine setting of lens sleeve 46 place light path, and reaches to mend Repay processing and rigging error, the purpose of optimization infomation detection.The detection module 4 being completed will be by detecting lens mount 40 Periphery 400 coordinate location with the main body 11 side through hole 113 of cavity module 1, will detection lens mount 40 counter sink 401 are connected with the screwed hole 112 on main body 11 side of cavity module 1, connect fixing with cavity module 1 for detection module 4 Connect.

Manual adjustment module

Fig. 6 shows the decomposition texture of manual adjustment module 5, and Figure 28 to Figure 32 shows each composition of manual adjustment module 5 The structure of parts.As shown in Figure 6, manual adjustment module 5 includes that height adjustment mechanism and angle adjusting mechanism, height are adjusted Joint mechanism include highly regulating ion source(-)holder 50, angle adjusting mechanism include angular adjustment ion source(-)holder 51, front-slider 52, Ion gun fixed mount 53, rear slider 54, slider locking screw head 55 and ion gun locking screw head 56, wherein:

As shown in figure 28, height regulation ion source(-)holder 50 is provided with the cylinder 500 of circular end cap 501, circular end cap for top The diameter of 501 is more than the diameter of cylinder 500, and the middle part of circular end cap 501 offers elongated hole, and circular end cap 501 is provided with For connecting the fixed angle regulation counter sink 502 of ion source(-)holder 51, pin-and-hole 503 and for connecting electric translation module 7 Screw 504, the drum surface being perpendicular to this elongated hole length direction is provided with altitude scale 505；Highly regulation ion gun Seat 50 can move up and down under the drive of electric translation module, and altitude scale 505 is used for indicating its height, and Height Adjustment is complete By the screwed hole 104 of counter sink 103 and 101 part of 102 parts on the clamp system 10 of cavity module 1 after one-tenth In be screwed into regulation bolt, by height regulation ion source(-)holder 50 be locked.

As shown in figure 29, angular adjustment ion source(-)holder 51 is strip plate body, and middle part is provided with and height regulation ion source(-)holder The elongated hole that 50 positions and dimensions are corresponding, be formed around and the height of this elongated hole regulate the counter sink 502 of ion source(-)holder 50 Corresponding screw 510 and the pin-and-hole 511 corresponding with pin-and-hole 503；Dual-side on this plate body length direction upwards one Being extended with two arc-shaped guide rails 512, the upper limb of this guide rail 512 is respectively provided with and outward extends flange, on the outer surface of guide rail 512 It is provided with angle index 513；Pin-and-hole by the pin-and-hole 503 of height regulation ion source(-)holder 50 with angular adjustment ion source(-)holder 51 511 position, and are connected by screw the two counter sink 502 and screw 510, just height regulation ion source(-)holder 50 Fix with angular adjustment ion source(-)holder 51 and be connected.

As shown in Figure 30, Figure 31 and Figure 32, front-slider 52 is the slide block that shape is identical with rear slider 54, sets in the middle part of slide block There is an arc groove of arc-shaped guide rail 512 mating shapes with angular adjustment ion source(-)holder 51, and same arc groove is upper Cambered surface 502/541 width is more than its lower camber side 521/541, and slide block side surface upper part is provided with cone head hole 523, is used for connecting ion Source fixed mount 53, front-slider 52 side lower is provided with an angle index instruction line, for indicating the angle of esi ion source, Rear slider 54 side lower is provided with screw 543, locks screw head 55 for connection sliding block；Ion gun fixed mount 53 be bottom surface in The plate body of arc, is provided with through hole 530 in the middle part of plate body, the diameter of this through hole 530 and the elongated hole of angular adjustment ion source(-)holder 51 Width corresponding, the side in this plate body arcuately direction, bottom surface is respectively provided with screw 531 and 533, be respectively used to connect Front-slider 52 and rear slider 54, outside side, side is provided with screw 532, is used for connecting ion gun locking screw head 56.

Front-slider 52, ion gun fixed mount 53, rear slider 54 slider locking screw head 55 and ion gun locking screw head 56 coordinate Using, concrete assembling process is as follows: front-slider 52 and rear slider 54 symmetry are installed in the arc of angular adjustment ion source(-)holder 51 On the flange of shape guide rail 512, the upper lower camber side of its arc groove fits with the flange of arc-shaped guide rail 512, and ion gun is solid Determine frame to be fixed between front-slider 52 and rear slider 54, and be positioned on described arc-shaped guide rail 512, by the cone of front-slider 52 Head bore 523 is connected with the screw 532 of ion gun fixed mount 53, is connected fixing with ion gun fixed mount 53 for front-slider 52； It is connected with the screw 533 of ion gun fixed mount 53 by the cone head hole 542 of rear slider 54, rear slider 54 is solid with ion gun Determine the fixing connection of frame 53；The arc of upper cambered surface 520 and 541, lower camber side 521 and 540 and angular adjustment ion source(-)holder 51 is led The flange of rail 512 is slidably matched, front-slider 52, ion gun fixed mount 53 together with rear slider 54 at angular adjustment ion gun Sliding on the arc-shaped guide rail 512 of seat 51, position can be indicated by the angle index 513 before angular adjustment ion source(-)holder 51； Inserting esi ion source 6 in the through hole 530 of ion gun fixed mount 53, esi ion source 6 is by height regulation ion source(-)holder 50 Stretch in the cylinder that height regulates ion source(-)holder 50 with the elongated hole of angular adjustment ion source(-)holder 51；Ion gun locking screw head 56 The side screw 532 being screwed into ion gun fixed mount 53 is interior in order to lock esi ion source 6；After slider locking screw head 55 is screwed into In order to fixed ion source fixed mount 53 in screw 543 after slide block 54, now the position of esi ion source 6 is fixed. Front-slider 52, ion gun fixed mount 53, rear slider 54, slider locking screw head 55, ion gun locking screw head 56 can be single Solely use, absorb for studying the gaseous ion light of material；Similarly, can expand to many after structure being changed a little Individual esi ion source 6.

Electrospray ionization source module

As it is shown in fig. 7, esi ion source 6 is syringe-shaped structure, upper end cylinder base is provided with gas passage 60 and sample channel 61, middle cylinder is provided with scale, and needle-like position, lower end is provided with matrix 62.Sample channel 61 connects an injector, uses In introducing testing sample, the front end of this injector is provided with stainless steel needle tubing, and high-voltage power supply is connected to this stainless steel needle tubing, when Sample solution passes through in stainless pin pipe, and high pressure can be added on sample solution.Gas passage 60 introduces high pressure nitrogen (N₂), charged testing sample is under the effect of high pressure nitrogen, and the head at matrix 62 forms spraying, and shape is Taylor Taper, forms the gaseous ion of sample.

Electric translation module

Fig. 8 shows the stereochemical structure of electric translation module 7, and Figure 33 to Figure 37 shows each group of electric translation module 7 Become the structure of parts.As shown in Figure 8, electric translation module 7 includes linking arm 70, clamp nut 71, electric platforms seat 72, screw support bearings 73, screw rod 74, feeding slide unit 75, nut 76, bearing (ball) cover 77, yielding coupling 78, Brake type stepper motor 79 and two polished rods 710, wherein:

As shown in figure 33, electric platforms seat 72 is rectangle plate body, and the separation of its upper side is provided with only three side walls, The both walls in outside is positioned at the both ends of plate body, and plate body top is provided with multiple counter sink 725, itself and the master of cavity module 1 Screw 118 on body 11 side is connected, and is used for fixing electric translation module 7；Be provided with on each side wall be centrally located at same The circular hole 720 and 723 of horizontal plane, the both sides of circular hole 720 are respectively provided with side opening 721, and the side opening 721 of middle side wall is not through this Side wall, and the side opening 721 of end side wall runs through this side wall, for fixed installation two polished rods 710；The surrounding of circular hole 723 sets There is multiple screwed hole 724, be used for connecting brake type stepper motor 79.

As shown in figure 35, feeding slide unit 75 is square block, between side wall and the middle side wall at through hole 721 place, Its upper side is provided with screwed hole 755, for connecting the side plate of the inverted "L" shaped linking arm 70 of electric translation module 7, left The middle part of side (left side of Figure 35) is provided with oval-shaped groove, offers through hole 753, around through hole 753 in the middle part of groove Groove floor be provided with multiple screw 754, be used for connecting fixing nut 76；The both sides of groove are provided with side opening 750, should The center of gaging hole 750 and side opening 721 are centrally located at same level, are used for wearing two polished rods 710.

Two screw support bearings 73 are respectively placed in circular hole 720, and screw rod 74 is each passed through the screw support on the side wall of end Screw support bearings 73 on bearing 73, the through hole 753 of feeding slide unit 75, nut 76 and middle side wall；Such as Figure 37 institute Showing, bearing (ball) cover 77 is annulus part, and middle part is by being connected the screw thread of bearing (ball) cover 77 with the circular hole 720 on middle side wall Hole 771 and the screw of middle side wall, be fixed on the right side of middle side wall by joint bearing end cap 77, and then by the side wall of centre Screw support bearings 73 fix, screw rod left part and spring bearing 73 clamp nut 71 are fixed；As shown in figure 36, Nut 76 is the tubular nut of hollow, and one end has end cap, and this end cap is provided with counter sink 761, and its cylinder 760 is from entering It is inserted in the counter sink in the through hole 753 of feeding slide unit 75, on the end cap of nut 76 to the oval-shaped groove side of slide unit 75 761 are connected with the screw 754 of feeding slide unit 75, are connected fixing to nut 76 and feeding slide unit；The right-hand member of screw rod 74 passes through Yielding coupling 78 is connected with the output shaft of brake type stepper motor 79, and brake type stepper motor 79 is connected to right side side wall Screwed hole 724, and its output shaft is connected through the circular hole 723 of right side side wall with yielding coupling 78.

The right-hand member of inverted "L" shaped linking arm 70 is fixed on the screwed hole 755 connecting given slide unit 75 by screw, linking arm The left end of 70 is fixed on the screw 504 connecting height regulation ion source(-)holder 50 by screw, when brake type stepper motor 79 During rotation, feeding slide unit 75 can be driven to move up and down, and then band dynamic height regulation ion source(-)holder 50 upper and lower translation, it is achieved It is automatically adjusted the purpose of esi ion source 6 height.

Being more than the final assembly explanation of the present invention, feature and its detection target according to detection object are adjusted making With.

The liquid phase sample of the present invention and gaseous ion light thereof absorb information detector flexible configuration, easy to use, available In the light absorption information of the gaseous ion that detection liquid phase sample is generated by normal pressure ESI technology, gaseous ion also can be realized from liquid State is changed into the continuous detection of the process of gaseous state, the most also can realize the conventional liquid phase sample light of detection and absorb information, its In:

Use one: the light of the gaseous ion that liquid phase sample is generated by normal pressure ESI technology absorbs infomation detection

When carrying out the light absorption infomation detection of the gaseous ion that liquid phase sample is generated by normal pressure ESI technology, need light source die Block 2, detection module 4, manual adjustment module 5, esi ion source 6 and electric translation module 7 are assembled to cavity module 1 On, and connect follow-up optical signal detecting equipment.

The light path of light source module 2 is coaxial with detection module 4, and the light source coaxially the most incident light absorption signal produced compares light source The light absorption signal that vertical incidence produces is a lot of by force, so light absorbs infomation detection and uses light path and detection module 4 with coaxial Layout type.

Utilize the gaseous ion light that assembly of the invention performs to absorb information detecting method and include following operating procedure:

(1) according to above-mentioned assembly relation, by light source module 2, detection module 4, manual adjustment module 5, single spraying Ion gun 6 and electric translation module 7 are assembled in cavity module 1, and regulate a spike 14 of cavity module 1, make this dress Put and be horizontal (can be adjusted by easy spirit bubble)；

(2) connection have the optical fiber of optical signal detecting equipment be connected in the optical fiber screw head 48 of detection module 4；

(3) at the sample channel 61 of esi ion source 6, connect an injector, injector be passed through to sample channel 61 Sample solution, is passed through gas at gas passage 60, the nitrogen of such as 1MPa；The stainless steel being provided with in injector front end Needle tubing accesses high pressure (such as ,+3KV) conductor wire end and connects high pressure；

(4) open the LED light source 21 (or laser) of light source module 2, and open optical signal detecting equipment and detect；

(5) by the height of electric translation module 7 adjustable spraying ion gun 6, change from liquid phase to gas phase in sample ions During, the light of detection sample ions absorbs information, to obtain the relation of esi ion source 6 height parameter and testing result.

Use two: the light of liquid phase sample absorbs infomation detection

Cuvette 17 and cuvette deck 16 are the conventional liquid phase optical information detections being exclusively used in material, therefore, when carrying out When the light of conventional liquid phase sample absorbs infomation detection, need light source module 2, detection module 4 are assembled to cavity module 1 On, and the cuvette 17 that will be equipped with sample solution puts in the top slot 161 of cuvette deck 16, puts into chamber the most together In the inside groove 121 of the base 12 of module 1 and with the upper through-hole of capping closed cavity module 1, and connect follow-up light letter Number detection equipment.

Utilize the liquid phase sample light that assembly of the invention performs to absorb information detecting method and include following operating procedure:

(1) according to above-mentioned assembly relation, light source module 2, detection module 4 are assembled in cavity module 1, and regulate A spike 14 of cavity module 1, makes this device be horizontal (can be adjusted) by easy spirit bubble；

(2) cuvette 17 by cuvette deck 16 and equipped with fluid sample assembles the bottom putting into cavity module 1 afterwards Groove 121 in, the upper through-hole of cavity module 1 uses capping to close；

(3) connection have the optical fiber of optical signal detecting equipment be connected in the optical fiber screw head 48 of detection module 4；

(4) open the LED light source 21 (or laser) of light source module 2, and open optical signal detecting equipment and carry out liquid phase Sample light absorbs infomation detection.

It will be appreciated by those skilled in the art that these embodiments are merely to illustrate the present invention and do not limit the scope of the invention, The various equivalent variations being made the present invention and amendment belong to the disclosure of invention.

Claims

1. the gaseous ion light of liquid phase sample absorbs an information detector, including light source module, detection module, spray Mist ion gun and for fixing the cavity module of above-mentioned each parts, it is characterised in that:

The gaseous ion light of liquid phase sample the most according to claim 1 absorbs information detector, it is characterised in that Also include manual adjustment module；Described manual adjustment module includes height adjustment mechanism and angle adjusting mechanism, wherein, Height adjustment mechanism is set in the described upper through-hole of cavity module movably, and angle adjusting mechanism is fixed on height The upper end of governor motion, the two is respectively equipped with the elongated hole that the chamber with cavity module is connected, and esi ion source is through height Degree governor motion, the elongated hole of angle adjusting mechanism stretch in the chamber of cavity module.

The gaseous ion light of liquid phase sample the most according to claim 2 absorbs information detector, it is characterised in that Described height adjustment mechanism includes highly regulating ion source(-)holder, and height regulation ion source(-)holder is the cylinder that top is provided with end cap, Cylinder is set in the described upper through-hole of cavity module, and the size of end cap is more than the diameter of cylinder, and the middle part of end cap is opened It is provided with described elongated hole；Angle adjusting mechanism includes angular adjustment ion source(-)holder, and it is fixed on height regulation by pilot hole On the end cap of ion source(-)holder, middle part is provided with the described elongated hole that the positions and dimensions with height regulation ion source(-)holder matches, Dual-side on described plate body length direction is the most integrally extended with two arc-shaped guide rails, and the upper limb of this guide rail is respectively provided with outwards The flange extended；

4. absorbing information detector according to the gaseous ion light of the liquid phase sample described in Claims 2 or 3, its feature exists In, the top of described cavity module is additionally provided with clamp system, and it is double-deck plate body, is provided with described in the middle part of described plate body The through hole that the upper through-hole of cavity module is connected with chamber, a top plate part is connected with lower plywood one, another portion Divide and separate with lower plywood, and be broken as the first clamping part and the second clamping part in a certain position of partitioning portion, first Clamping part and the second clamping part are provided with regulation bolt, make the first clamping part and the second clamping part generation bullet by regulation bolt Property deformation, lock or discharge the manual adjustment module installed in through hole.

5. absorb information detector according to the gaseous ion light of the liquid phase sample described in any one of claim 2 to 4, its It is characterised by, also includes electric translation module；Described electric translation module is arranged on the side of cavity module, and with Manual adjustment module is connected, it is possible to drive manual adjustment module to move up and down together with esi ion source；Described electronic flat Shifting formwork block includes linking arm, electric platforms seat, screw support bearings, screw rod, feeding slide unit, brake type stepper motor With two polished rods；Wherein:

6. liquid phase sample light absorbs an information detector, and it is annular seal space cell structure, including light source module, detection Module, for fixing the cavity module of above-mentioned each parts, the cuvette being placed in cavity module and described for sealing The capping of cavity module, it is characterised in that:

Cavity module is to be provided with the cavity body structure of through hole, and it is relative that light source module is individually fixed in cavity module with detection module The through hole of two sides, light source module is centrally located in same level with the light path of detection module, and light source module Light path central coaxial with detection module；

Cuvette equipped with sample solution is placed in the chamber of cavity module, and is positioned at described light source module and detection module Light Lu Zhizheng；

Described capping is the cylinder that top is provided with circular end cap, and the diameter of circular end cap is more than the diameter of cylinder, and cylinder is put In the through hole on cavity module top；

Described cavity module bottom is provided with groove, is provided with the screw for connected drainage pipe joint in the middle part of groove；Equipped with sample The cuvette of product solution is positioned in the groove at a cuvette deck top, and the bottom of cuvette deck is placed at the bottom of cavity module In the groove in portion.

7. according to the gaseous ion light of the liquid phase sample described in any one of claim 1 to 5 absorb information detector or Liquid phase sample light described in any one of claim 6 absorbs information detector, it is characterised in that described light source module Sealing plate, LED light source, filter and planoconvex spotlight it is sequentially provided with from outside to inside, wherein, outside being used for isolating in source path The sealing plate of boundary's light is positioned at outermost end, and LED light source is installed on a LED and installs in set；Filter, planoconvex spotlight are installed on In lens sleeve, lens sleeve is installed in the inner core of a light lens seat, and described light lens seat one end is connected to chamber On the one side of module, the other end and LED install set airtight connection, and LED installs the other end of set and fixes with sealing plate Connect；One lens stage clip and lens sleeve are installed in the inner core of described light lens seat successively；Described LED install set with Light lens seat connects with adjustable thread, is screwed into LED by control and installs the degree of depth realization of set to planoconvex spotlight and cavity mould The distance of block is finely adjusted.

The gaseous ion light of liquid phase sample the most according to claim 7 absorbs information detector or liquid phase sample Light absorbs information detector, it is characterised in that described light source module also includes that described slit base, described slit base are The framework of hollow, this framework is sequentially installed with microdrum, movable plate, wear-resistant sleeve, polished rod, fixed plate from top to bottom, Wherein, microdrum bottom is inserted in the through hole of slit base upper side, and the end face of movable plate is withstood in its lower end；Fixed plate With movable plate be two block-shaped similar and with the use of trapezoidal plate, the inclined-plane of two boards relatively and inclined-plane drift angle limit with Side is placed and is formed slit, and polished rod sequentially passes through wear-resistant sleeve and a slit stage clip, and is fixed on fixed plate by pilot hole And between movable plate；Movable plate can be made to move up and down by rotating microdrum, be formed between movable plate and fixed plate Slit light belt is adjustable.

9. absorb information detector or liquid phase sample according to the gaseous ion light of the liquid phase sample described in claim 7 or 8 Product light absorbs information detector, it is characterised in that described detection module is sequentially provided with inspection in its light path received Surveying lens mount, filter, planoconvex spotlight, optical fiber set and optical fiber screw head, wherein, filter, that planoconvex spotlight is installed on one is saturating In mirror sleeve cylinder；Lens sleeve is installed in detection lens mount, and detection lens mount one end is installed on the one side of cavity module On, the other end overlaps airtight connection with the optical fiber equipped with optical fiber screw head；One lens stage clip and lens sleeve are installed on institute successively State in the inner core of detection lens mount；Described detection lens mount is connected with adjustable thread with optical fiber set, is screwed into light by control The degree of depth of fine set realizes being finely adjusted detection module light path.

10. according to the gaseous ion light of the liquid phase sample described in any one of claim 1 to 9 absorb information detector or Person's liquid phase sample light absorbs information detector, it is characterised in that the bottom of described cavity module is provided with base, base Corner be respectively fixedly connected with supporting leg, supporting leg lower end connects the spike having for supporting cavity module；Described The bottom surface propping up spike is cone, and upper end is provided with screw head, and screw head is connected with the screwed hole of supporting leg lower end, and regulation supports The screw head of pin is screwed into the degree of depth to regulate the levelness of cavity module.

The gaseous ion light of 11. 1 kinds of liquid phase samples absorbs information detecting method, uses claim 1 to 5 or 7 to 10 According to any one of liquid phase sample gaseous ion light absorb information detector detect, comprise the following steps:

12. 1 kinds of liquid phase sample light absorb information detecting method, use the liquid phase sample described in any one of claim 6 to 10 Product light absorbs information detector and detects, and comprises the following steps: