CN105854073B - Glass ceramics for tooth-implanting - Google Patents
Glass ceramics for tooth-implanting Download PDFInfo
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- CN105854073B CN105854073B CN201610352688.9A CN201610352688A CN105854073B CN 105854073 B CN105854073 B CN 105854073B CN 201610352688 A CN201610352688 A CN 201610352688A CN 105854073 B CN105854073 B CN 105854073B
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- parts
- glass ceramics
- zinc
- silica
- tooth
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- 239000002241 glass-ceramic Substances 0.000 title claims abstract description 27
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 36
- CPLXHLVBOLITMK-UHFFFAOYSA-N Magnesium oxide Chemical compound [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 claims abstract description 26
- DLYUQMMRRRQYAE-UHFFFAOYSA-N tetraphosphorus decaoxide Chemical compound O1P(O2)(=O)OP3(=O)OP1(=O)OP2(=O)O3 DLYUQMMRRRQYAE-UHFFFAOYSA-N 0.000 claims abstract description 26
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims abstract description 22
- 239000004810 polytetrafluoroethylene Substances 0.000 claims abstract description 22
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims abstract description 18
- 239000000377 silicon dioxide Substances 0.000 claims abstract description 18
- 229910052725 zinc Inorganic materials 0.000 claims abstract description 18
- 239000011701 zinc Substances 0.000 claims abstract description 18
- 238000005245 sintering Methods 0.000 claims abstract description 16
- 239000001856 Ethyl cellulose Substances 0.000 claims abstract description 13
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims abstract description 13
- 229920001249 ethyl cellulose Polymers 0.000 claims abstract description 13
- 235000019325 ethyl cellulose Nutrition 0.000 claims abstract description 13
- 239000000395 magnesium oxide Substances 0.000 claims abstract description 13
- 238000002360 preparation method Methods 0.000 claims abstract description 13
- HBMJWWWQQXIZIP-UHFFFAOYSA-N silicon carbide Chemical compound [Si+]#[C-] HBMJWWWQQXIZIP-UHFFFAOYSA-N 0.000 claims abstract description 13
- 229910010271 silicon carbide Inorganic materials 0.000 claims abstract description 13
- -1 polytetrafluoroethylene Polymers 0.000 claims abstract description 12
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 claims abstract description 8
- 235000019700 dicalcium phosphate Nutrition 0.000 claims abstract description 8
- 239000002994 raw material Substances 0.000 claims abstract description 8
- 238000010791 quenching Methods 0.000 claims abstract description 7
- 230000000171 quenching effect Effects 0.000 claims abstract description 7
- 238000012216 screening Methods 0.000 claims abstract description 6
- NBIIXXVUZAFLBC-UHFFFAOYSA-N phosphoric acid Substances OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims description 9
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 5
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims description 5
- 229910052791 calcium Inorganic materials 0.000 claims description 5
- 239000011575 calcium Substances 0.000 claims description 5
- 229910052739 hydrogen Inorganic materials 0.000 claims description 5
- 239000001257 hydrogen Substances 0.000 claims description 5
- 239000011521 glass Substances 0.000 abstract description 11
- 238000000034 method Methods 0.000 abstract description 8
- 238000005336 cracking Methods 0.000 abstract description 6
- 239000000843 powder Substances 0.000 abstract description 4
- 239000000463 material Substances 0.000 description 12
- 210000001519 tissue Anatomy 0.000 description 11
- 239000000919 ceramic Substances 0.000 description 9
- 239000007943 implant Substances 0.000 description 5
- 238000011160 research Methods 0.000 description 5
- 210000000988 bone and bone Anatomy 0.000 description 4
- 125000004435 hydrogen atom Chemical class [H]* 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 230000000975 bioactive effect Effects 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000003519 biomedical and dental material Substances 0.000 description 2
- 239000001506 calcium phosphate Substances 0.000 description 2
- 239000013078 crystal Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
- 239000005977 Ethylene Substances 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- 229910052586 apatite Inorganic materials 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 238000005842 biochemical reaction Methods 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- YYRMJZQKEFZXMX-UHFFFAOYSA-L calcium bis(dihydrogenphosphate) Chemical compound [Ca+2].OP(O)([O-])=O.OP(O)([O-])=O YYRMJZQKEFZXMX-UHFFFAOYSA-L 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- 239000012876 carrier material Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000000280 densification Methods 0.000 description 1
- 210000003298 dental enamel Anatomy 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 1
- 230000008676 import Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000013081 microcrystal Substances 0.000 description 1
- 235000019691 monocalcium phosphate Nutrition 0.000 description 1
- 229910000150 monocalcium phosphate Inorganic materials 0.000 description 1
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 1
- 238000011056 performance test Methods 0.000 description 1
- 239000002367 phosphate rock Substances 0.000 description 1
- OJMIONKXNSYLSR-UHFFFAOYSA-N phosphorous acid Chemical compound OP(O)O OJMIONKXNSYLSR-UHFFFAOYSA-N 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/10—Ceramics or glasses
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C10/00—Devitrified glass ceramics, i.e. glass ceramics having a crystalline phase dispersed in a glassy phase and constituting at least 50% by weight of the total composition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/025—Other specific inorganic materials not covered by A61L27/04 - A61L27/12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/04—Metals or alloys
- A61L27/047—Other specific metals or alloys not covered by A61L27/042 - A61L27/045 or A61L27/06
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
- C03B19/00—Other methods of shaping glass
- C03B19/06—Other methods of shaping glass by sintering, e.g. by cold isostatic pressing of powders and subsequent sintering, by hot pressing of powders, by sintering slurries or dispersions not undergoing a liquid phase reaction
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C1/00—Ingredients generally applicable to manufacture of glasses, glazes, or vitreous enamels
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C10/00—Devitrified glass ceramics, i.e. glass ceramics having a crystalline phase dispersed in a glassy phase and constituting at least 50% by weight of the total composition
- C03C10/0009—Devitrified glass ceramics, i.e. glass ceramics having a crystalline phase dispersed in a glassy phase and constituting at least 50% by weight of the total composition containing silica as main constituent
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C10/00—Devitrified glass ceramics, i.e. glass ceramics having a crystalline phase dispersed in a glassy phase and constituting at least 50% by weight of the total composition
- C03C10/009—Devitrified glass ceramics, i.e. glass ceramics having a crystalline phase dispersed in a glassy phase and constituting at least 50% by weight of the total composition having a superconducting crystal phase
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C4/00—Compositions for glass with special properties
- C03C4/0007—Compositions for glass with special properties for biologically-compatible glass
- C03C4/0021—Compositions for glass with special properties for biologically-compatible glass for dental use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/112—Phosphorus-containing compounds, e.g. phosphates, phosphonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/202—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with halogen atoms, e.g. triclosan, povidone-iodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/23—Carbohydrates
- A61L2300/232—Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/12—Materials or treatment for tissue regeneration for dental implants or prostheses
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Geochemistry & Mineralogy (AREA)
- Dispersion Chemistry (AREA)
- Ceramic Engineering (AREA)
- Inorganic Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Manufacturing & Machinery (AREA)
- Molecular Biology (AREA)
- Materials For Medical Uses (AREA)
- Dental Preparations (AREA)
- Glass Compositions (AREA)
- Compositions Of Oxide Ceramics (AREA)
Abstract
The invention discloses a kind of glass ceramics for tooth-implanting, the raw material including following parts by weight meter: 50 ~ 70 parts of silica, 20 ~ 70 parts of magnesia, 30 ~ 40 parts of calcium monohydrogen phosphate, 20 ~ 30 parts of phosphorus pentoxide, 15 ~ 25 parts of silicon carbide, 10 ~ 20 parts of zinc, 12 ~ 20 parts of polytetrafluoroethylene (PTFE), 30 ~ 40 parts of ethyl cellulose.Preparation method: silica, magnesia, calcium monohydrogen phosphate, phosphorus pentoxide, silicon carbide, zinc, polytetrafluoroethylene (PTFE), ethyl cellulose are uniformly mixed, and after fusing, are heated to 1300 ~ 1400 DEG C, are reacted 2 ~ 3h；Quenching crushes, screening, cold moudling；Sintering.The present invention first forms and powder is made, and is then prepared into glass ceramics again, can prevent from being directly formed to structural glass and cracking, and improves product quality；And the product porosity that the method according to the invention is prepared is small, closely without cracking.
Description
Technical field
The present invention relates to biological medicine Material Fields more particularly to a kind of for the glass ceramics of tooth-implanting and its preparation side
Method.
Background technique
Although the research of China's bio-medical material obtains some achievements to attract people's attention, integral level is not high, tracking
Research is more, and source treatment is few.In terms of industrialization, the share that bio-medical material and its product account for world market is led less than 2%
Import is relied on, product technology structure and level lie substantially in the primary stage.
Biodegradable ceramic refers to that the implant does not cause the feelings of any undesirable tissue reaction after being implanted to tissue
It is gradually dissolved under condition, and replaced newborn tissue.The biodegradable ceramic of present I clinical application specifically includes that hydroxyl
Apatite and mono- calcium phosphate of β are usually the film either porous material for being used as metal implant.Due to its main component and people
The inanimate matter of bone is close, thus have person it be " artificial bone ".It after being implanted to human body by human body metabolism gradually by
Newly-generated tissue replaces, and when as porous material, the porosity of general material is 60~70%, and to the microcosmic hole of material
Gap has certain requirement, generally requires 100 cave of hole master, and is interconnected between hole.Growth of this porosity to tissue
Be it is highly advantageous, the mineralized tissue of bone can enter and be filled into the hole of material with fibrous connective tissue and be fixed, this
Permanent reparation to physiological is essential.But the intensity of the material is low and crisp, therefore is not suitable for propping up when use
Weight position, because the bending force at these positions, distorting stress are transmitted to the fracture that will lead to implant after implant.Therefore normal quilt
The alternate material at the position less big for root of the tooth and stress and the filler in bone vacancy.
Bioactive ceramics are proposed by Hench L.L et al. first, refer to that this material can be with around after being implanted in vivo
Biochemical reaction occurs for tissue, so that forming bioconjugation between implant and tissue.This mainly include bio-vitric and
Biological glass ceramic composite material.The biocompatibility of bioactive ceramics is between inactive ceramic and degradable ceramics, tool
There is good biocompatibility, has no toxic side effect.Further, since it chemical composition and skeleton composition it is closely similar,
After being implanted in tissue, it is easy the chemical bonding for organizing the formation of close and firm with surrounding, or formed through biodegrade
New tissue.The research and clinical application of bioactive ceramics have become such as materialogy, medicine and biochemistry
The research hotspot of section, is increasingly valued by people, and especially some high intensity, machinable glass ceramics are ceramic and are used for
Functional glass ceramics of therapeutical uses researchs and develops, and opens new road for the medical treatment of the mankind.Kyoto Univ Japan is small
The Kubo Orthodox Church invests nineteen eighty-two and successfully has developed apatite and 34% or so wollastonites containing 38wt% or so
(wo1lastonite) devitrified glass, that is, usually said A/w glass.This glass not only has preferable mechanical property
Can, and can be formed with tissue in conjunction with stronger biochemistry.The phosphorite crystal content being precipitated from glass matrix is not
Only there is large effect to the mechanical property of material, and it plays conclusive effect to the bioactivity of material.From glass
The crystal grain that matrix is precipitated has outside the Pass in addition to the raw material with material, and the heat treatment process in crystallization process also has very big shadow to it
It rings, it is therefore necessary to which stringent control is carried out to the preparation process of material.It selects suitable ingredient and heat treatment process is to prepare this
The key of kind material.Machinable bio-microcrystal glass due to its good cutting ability, simultaneously because its milkiness characteristic with from
Right enamel is very close, quality densification, wear-resisting, any surface finish, good Biocompatibility and chemical stability, therefore
It gains great popularity in all-ceramic crown dummy.Especially in recent years, as CAD/auxiliary manufactures (cAD/cAM) technology
Popularization and application, for machinable glass ceramic in oral restoration application open new road.In conclusion glass base is raw
The compositional system of object carrier material substantially still falls within calcium phosphate system composition, but raw not influencing glass ceramics
On the basis of object compatibility and bioactivity, in order to improve the mechanical property, processing performance or some other property of biomaterial
Can, the substance of certain other components can be added, dosage is related with preparation method and preparation process.
Summary of the invention
The glass ceramics and preparation method thereof that in view of the deficiencies of the prior art, the present invention provides a kind of for tooth-implanting, glass
Glass ceramics porosity is small, closely without cracking.
In order to solve the above-mentioned technical problem, the invention adopts the following technical scheme:
For the glass ceramics of tooth-implanting, the raw material including following parts by weight meter: 50~70 parts of silica, magnesia 20
~70 parts, 30~40 parts of calcium monohydrogen phosphate, 20~30 parts of phosphorus pentoxide, 15~25 parts of silicon carbide, 10~20 parts of zinc, polytetrafluoroethyl-ne
12~20 parts of alkene, 30~40 parts of ethyl cellulose.
As a further refinement of the present invention, it is used for the glass ceramics of tooth-implanting, the raw material including following parts by weight meter:
60 parts of silica, 40 parts of magnesia, 35 parts of calcium monohydrogen phosphate, 25 parts of phosphorus pentoxide, 20 parts of silicon carbide, 15 parts of zinc, polytetrafluoro
15 parts of ethylene, 35 parts of ethyl cellulose.
As a further refinement of the present invention, the partial size of silica is 30~60 μm.
As a further refinement of the present invention, the partial size of zinc is 60~200 μm.
The present invention also provides a kind of preparation methods of glass ceramics for tooth-implanting.
A kind of preparation method of the glass ceramics for tooth-implanting, comprising the following steps: silica, magnesia, phosphoric acid
Hydrogen calcium, phosphorus pentoxide, silicon carbide, zinc, polytetrafluoroethylene (PTFE), ethyl cellulose are uniformly mixed, after fusing, it is heated to 1300~
1400 DEG C, react 2~3h；Quenching crushes, screening, cold moudling；Sintering.
As a further refinement of the present invention, sintering temperature is 1050 DEG C, sintering time 2h.
The utility model has the advantages that the present invention using first molding powder is made, be then prepared into glass ceramics again, can prevent directly at
Type cracks for structural glass, improves product quality；And the product porosity that the method according to the invention is prepared is small, tightly
Close no cracking, porosity only 18~21%, can apply on tooth-implanting.
Specific embodiment
The present invention is further explained in the light of specific embodiments.
Embodiment 1
For the glass ceramics of tooth-implanting, the raw material including following parts by weight meter: 60 parts of silica, 40 parts of magnesia,
35 parts of calcium monohydrogen phosphate, 25 parts of phosphorus pentoxide, 20 parts of silicon carbide, 15 parts of zinc, 15 parts of polytetrafluoroethylene (PTFE), 35 parts of ethyl cellulose.
The partial size of silica is 50 μm.
The partial size of zinc is 100 μm.
A kind of preparation method of the glass ceramics for tooth-implanting, comprising the following steps: silica, magnesia, phosphoric acid
Hydrogen calcium, phosphorus pentoxide, silicon carbide, zinc, polytetrafluoroethylene (PTFE), ethyl cellulose are uniformly mixed, and after fusing, are heated to 1350 DEG C,
React 2.5h；Quenching crushes, screening, cold moudling；Sintering.
Sintering temperature is 1050 DEG C, sintering time 2h.
Embodiment 2
For the glass ceramics of tooth-implanting, the raw material including following parts by weight meter: 50 parts of silica, 20 parts of magnesia,
30 parts of calcium monohydrogen phosphate, 20 parts of phosphorus pentoxide, 15 parts of silicon carbide, 10 parts of zinc, 12 parts of polytetrafluoroethylene (PTFE), 30 parts of ethyl cellulose.
The partial size of silica is 30 μm.
The partial size of zinc is 60 μm.
A kind of preparation method of the glass ceramics for tooth-implanting, comprising the following steps: silica, magnesia, phosphoric acid
Hydrogen calcium, phosphorus pentoxide, silicon carbide, zinc, polytetrafluoroethylene (PTFE), ethyl cellulose are uniformly mixed, and after fusing, are heated to 1300 DEG C,
React 2h；Quenching crushes, screening, cold moudling；Sintering.
Sintering temperature is 1050 DEG C, sintering time 2h.
Embodiment 3
For the glass ceramics of tooth-implanting, the raw material including following parts by weight meter: 70 parts of silica, 70 parts of magnesia,
40 parts of calcium monohydrogen phosphate, 30 parts of phosphorus pentoxide, 25 parts of silicon carbide, 20 parts of zinc, 20 parts of polytetrafluoroethylene (PTFE), 40 parts of ethyl cellulose.
The partial size of silica is 60 μm.
The partial size of zinc is 200 μm.
A kind of preparation method of the glass ceramics for tooth-implanting, comprising the following steps: silica, magnesia, phosphoric acid
Hydrogen calcium, phosphorus pentoxide, silicon carbide, zinc, polytetrafluoroethylene (PTFE), ethyl cellulose are uniformly mixed, and after fusing, are heated to 1400 DEG C,
React 3h；Quenching crushes, screening, cold moudling；Sintering.
Sintering temperature is 1050 DEG C, sintering time 2h.
Comparative example 1
Same as Example 1, difference is: omitting step and " after fusing, is heated to 1350 DEG C, reacts 2.5h；Quenching ", directly
Connect the method preparation glass ceramics using powder compacting.
Performance test
The properties of product for measuring embodiment and comparative example, the results are shown in Table 1.
Table 1
Conclusion: porosity of the invention only 18~21%, the porosity well below comparative example 1 are 45%.This is because this
Powder is made using first molding in invention, is then prepared into glass ceramics again, can prevent from being directly formed to structural glass and cracking,
Improve product quality；The product porosity that the present invention is prepared is small, closely without cracking.
Claims (1)
1. being used for the glass ceramics of tooth-implanting, which is characterized in that the raw material including following parts by weight meter: silica 50~70
Part, 20~70 parts of magnesia, 30~40 parts of calcium monohydrogen phosphate, 20~30 parts of phosphorus pentoxide, 15~25 parts of silicon carbide, zinc 10~20
Part, 12~20 parts of polytetrafluoroethylene (PTFE), 30~40 parts of ethyl cellulose；
The partial size of silica is 30~60 μm, and the partial size of zinc is 60~200 μm；
The preparation method of the glass ceramics for tooth-implanting, comprising the following steps: silica, magnesia, phosphoric acid hydrogen
Calcium, phosphorus pentoxide, silicon carbide, zinc, polytetrafluoroethylene (PTFE), ethyl cellulose are uniformly mixed, and after fusing, are heated to 1300~1400
DEG C, react 2~3h；Quenching crushes, screening, cold moudling；Sintering；
Sintering temperature is 1050 DEG C, sintering time 2h.
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| CN201610352834.8A Pending CN105999399A (en) | 2014-11-10 | 2014-11-10 | Glass ceramic for implant teeth |
| CN201610353463.5A Active CN105948510B (en) | 2014-11-10 | 2014-11-10 | For the preparation method of the glass ceramics of tooth-implanting |
| CN201610352688.9A Expired - Fee Related CN105854073B (en) | 2014-11-10 | 2014-11-10 | Glass ceramics for tooth-implanting |
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| CN201610352458.2A Pending CN105999398A (en) | 2014-11-10 | 2014-11-10 | Glass ceramic with small porosity for implanting teeth |
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| CN101559237A (en) * | 2009-05-19 | 2009-10-21 | 山东大学 | ZrO2 toughened bioactive glass-ceramics of MgO-CaO-SiO2-P2O5-CaF2 system and preparation method thereof |
| CN102316911A (en) * | 2009-02-10 | 2012-01-11 | 阿祖瑞博有限公司 | Bone-regeneration material based on the combination of monetite and other biologically actived calcium and silicon compound |
| CN103172263A (en) * | 2013-04-16 | 2013-06-26 | 中国地质科学院 | Biological microcrystalline glass prepared by utilizing phosphate tailings and preparation method thereof |
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| US6878456B2 (en) * | 2001-12-28 | 2005-04-12 | 3M Innovative Properties Co. | Polycrystalline translucent alumina-based ceramic material, uses, and methods |
| CN1240637C (en) * | 2003-08-12 | 2006-02-08 | 四川大学 | Porous calcium phosphate bioceramic material and preparing method thereof |
| CN1325412C (en) * | 2005-10-24 | 2007-07-11 | 浙江大学 | Nano-multicrystal phase glass ceramics and its production method |
| US8916198B2 (en) * | 2006-04-25 | 2014-12-23 | Washington State University | Mesoporous calcium silicate compositions and methods for synthesis of mesoporous calcium silicate for controlled release of bioactive agents |
| BR112013032434B1 (en) * | 2011-06-22 | 2018-05-15 | Vita Zahnfabrik H. Rauter Gmbh & Co. Kg | DENTAL RESTORATION, ITS PRODUCTION METHOD, AND DENTAL CERAMIC GLASS |
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| CN104030718B (en) * | 2014-05-20 | 2015-08-19 | 广州医科大学 | Porous calcium carbonate ceramic of a kind of trace elements that adulterates and its preparation method and application |
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| CN102316911A (en) * | 2009-02-10 | 2012-01-11 | 阿祖瑞博有限公司 | Bone-regeneration material based on the combination of monetite and other biologically actived calcium and silicon compound |
| CN101559237A (en) * | 2009-05-19 | 2009-10-21 | 山东大学 | ZrO2 toughened bioactive glass-ceramics of MgO-CaO-SiO2-P2O5-CaF2 system and preparation method thereof |
| CN103172263A (en) * | 2013-04-16 | 2013-06-26 | 中国地质科学院 | Biological microcrystalline glass prepared by utilizing phosphate tailings and preparation method thereof |
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| CN104399115B (en) | 2016-08-24 |
| CN105999398A (en) | 2016-10-12 |
| CN104399115A (en) | 2015-03-11 |
| CN105903070B (en) | 2018-12-28 |
| CN106007382B (en) | 2018-08-28 |
| CN105948510B (en) | 2018-05-22 |
| CN105903070A (en) | 2016-08-31 |
| CN106007382A (en) | 2016-10-12 |
| CN106007383A (en) | 2016-10-12 |
| CN106007383B (en) | 2018-11-02 |
| CN105999399A (en) | 2016-10-12 |
| CN105948509A (en) | 2016-09-21 |
| CN105854073A (en) | 2016-08-17 |
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| CN105948509B (en) | 2018-06-29 |
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