CN105832356A - Radiography imaging parameter selection based on extant patient information - Google Patents

Radiography imaging parameter selection based on extant patient information Download PDF

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CN105832356A
CN105832356A CN201610077923.6A CN201610077923A CN105832356A CN 105832356 A CN105832356 A CN 105832356A CN 201610077923 A CN201610077923 A CN 201610077923A CN 105832356 A CN105832356 A CN 105832356A
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imaging
patient
radiograph
image
parameter
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CN105832356B (en
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P·佩桑
A·格拉夫
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Siemens Healthineers International AG
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Varian Medical Systems International AG
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    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00ICT specially adapted for the handling or processing of medical images
    • G16H30/20ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/54Control of apparatus or devices for radiation diagnosis
    • A61B6/545Control of apparatus or devices for radiation diagnosis involving automatic set-up of acquisition parameters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03Computed tomography [CT]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048Monitoring, verifying, controlling systems and methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048Monitoring, verifying, controlling systems and methods
    • A61N5/1049Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/60ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048Monitoring, verifying, controlling systems and methods
    • A61N5/1049Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A61N2005/1061Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using an x-ray imaging system having a separate imaging source

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Abstract

System and method for automatic radiography imaging parameter generation by use of extant patient information. The patient information is categorized, and one or more radiography imaging parameters of a radiographic device are selected and processed according to a knowledge-based model applied to a selection of at least one patient information category. A value for the selected imaging parameter(s) is output. Values for several imaging parameters may be automatically generated according to the processing and optimization. Alternatively, a value, or a range of values, may be suggested for presentation to a clinician. The processing and optimization of the radiography imaging parameters may be based on a subset of the patient information.

Description

Radiograph imaging parameters based on existing cases's information selects
Technical field
Embodiment of the disclosure and relate generally to imaging device, and relate more particularly to lonizing radiation Photograph imaging device.
Background technology
Radiotherapy (RT) is that the one for treatment of cancer is universal and efficient method, wherein The radiation of ionizing is used for intention and kills malignant cell or slow down its growth.RT is usual Combine with surgical operation, chemotherapy or hormone therapy but it also may be used as primary treatment pattern. Radiotherapy can be managed as internal RT or close-range treatment, or the most common outside is penetrated Bundle RT.
Internal RT treatment generally includes by one or more radioactive sources permanently or temporarily It is placed near the area for treatment specified.On the contrary, external beam RT is usually directed to by being positioned at Beam of radiation produced by the source outside relative to patient or radiation object guides extremely is rolled over by slight illness The area for treatment of mill.Beam can include photon, electronics, proton or other heavy ions;Photon (at present) is the most frequently used particle types.The ionizing that malignant cell is used during RT Radiation destroys.But, the destruction from radiation is not limited to malignant cell, and therefore, manages The dosage of the radiation to the health tissues beyond treatment volume (volume) is minimized with thinking with Those tissues are avoided to be destroyed similarly.
The purpose of tradition RT therapy planning method is to design to target volume generation as far as possible The therapeutic scheme of uniform metering distribution, and make the dosage outside this volume minimize.Generally, Such as X-ray equipment, computerized tomography image (CT), cone beam computed tomography image (CBCT) Or the imaging device of NMR (Nuclear Magnetic Resonance)-imaging (MRI) equipment etc is used for generating one or more The image in preliminary sweep or region interested (such as, in advance treatment plan image).Generally Ground, once has been achieved for image, exposes key structure (such as, district in the target area Territory or organ) identified especially, so that treatment can guide optimisedly.
Generally, before next-door neighbour's treatment session (session), but in treatment plan imaging session Afterwards, by imaging patients to confirm that patient positions and provide the region interested for treatment The checking of position.By the dose distribution calculated in the treatment plan stage and the agent being delivered to patient Amount distribution between minimum deviation successful radiotherapy it is critical that.Especially, It is integrated with patient location that the CBCT of radiographic apparatus can be used in IGRT and tests Card, particularly before next-door neighbour's radiotherapy session.
Normally, the essential experience and knowledge based on practitioner to particular patient history of practitioner Select suitable source dates (such as, source voltage and current, scan track) and image capturing Parameter (such as, frame rate, dynamic gain).Although make use of the Professional knowledge of people, but this The method of sample is also easy to occur mistake, inconsistent between different practitioners, and Can not utilize about the whole available information of this patient.
Summary of the invention
For the position fixing process of patient, imager source is set (such as, radiographic apparatus Set) and image capturing set be optimized ideally, in order to both obtained high-quality image The radiological dose of patient will be minimized the most simultaneously.Therefore, embodiment of the disclosure that use is existing The patient that such as obtains from treatment plan CT scan in advance of the specific information of patient become As such as to use kV/MV x-ray imaging system before next-door neighbour's radiotherapy Automatically generate and wait to be used for one or more imaging parameters of imaging patients.
Thering is provided this summary of the invention to introduce the selection to concept with reduced form, it is the most concrete Embodiment further describes.This summary of the invention is not intended as identifying theme required for protection Key feature or key character, be not intended to the scope being used for limiting theme required for protection.
According to embodiment of the disclosure, it is provided that a kind of for by using existing patient information Automatic radiograph imaging parameters generate system and method.Patient information is classified, and And the Knowledge based engineering model of at least one patient information categorizing selection is selected according to being applied to Select and process one or more radiograph imaging parameters of radiographic apparatus.Output pin Value to selected (multiple) imaging parameters.Can automatically generate according to processing and optimizing Value for some imaging parameters.It is alternatively possible to the scope of value, value is presented to face by suggestion Bed doctor.Process and the optimization of radiograph imaging parameters can subsets based on patient information.
More specifically, an aspect of this disclosure includes a kind of for generating for patient's The method of one or more parameters of radiographic image.The method includes receiving and for trouble The step of the patient information that the radiographic image of person is relevant.Based on the patient information received Determine at least one imaging class.One or more base is selected from some Knowledge based engineering models In the model of knowledge, make this selection according to imaging class.Join from some radiographic imagings Number selects one or more radiographic imaging parameters, makes this selection according to imaging class. According to the radiographic imaging parameters selected by one or more Knowledge based engineering models treated, For the radiographic imaging parameters selected by optimization, and the imaging ginseng selected by generation The value of number is as output.
Above-mentioned for summary of the invention, and the most necessarily comprise the simplification to details, summarize and omit; Therefore, artisan will appreciate that this summary of the invention is only illustrative and is not purport The most determinate.As the other aspects of the present invention being limited only by the appended claims, The indefiniteness specific embodiment that inventive feature and advantage will be illustrated below becomes Clear.
Accompanying drawing explanation
The accompanying drawing of the part being incorporated in and form this specification illustrates the enforcement of the present invention Example, and together with describing for the principle of the present invention is explained.
Fig. 1 describes the exemplary radiation therapy system according to disclosure embodiment.
The radiographic imaging parameters that illustrates that Fig. 2 describes according to disclosure embodiment generates system The functional block diagram of the exemplary configuration of system.
Fig. 3 describe according to disclosure embodiment for generate for radiographic imaging device The flow chart of method of imaging parameters.
Fig. 4 describe according to disclosure embodiment include optionally to the subset of patient data and/ Or to the consideration that Knowledge based engineering model manually selects, for generate for radiographic The flow chart of the method for the imaging parameters of imaging device.
Fig. 5 describes the exemplary computing environments according to disclosure embodiment.
Specific embodiment
With reference to some embodiments.Although theme will be described in conjunction with alternative, but It should be appreciated that they are not intended as theme required for protection is defined in these embodiments. On the contrary, theme required for protection is intended to alternative, amendment and equivalent, and it is permissible Be included in the theme required for protection limited such as appended claims spirit and In the range of.
Additionally, in being discussed in more detail below, illustrate multiple specific detail to provide required Comprehensive understanding of the theme of protection.But, it will be appreciated by the person skilled in the art that permissible Embodiment is put into practice in the case of there is no these specific detail or its equivalent.At other examples In, it is not described in known method, process and parts, in order to will not unnecessary topotype Stick with paste aspect and the feature of theme.
Present and discuss the part of following specific embodiment for a kind of method.Although herein Accompanying drawing in disclose step and order, but these steps of the method describing the method operation It is exemplary with order.Embodiment is very suitable for performing other steps various or at this paper accompanying drawing Flow chart in the deformation of described step, and to be different from depicted herein or statement Order.
Can be stored on some form of computer usable medium (such as program module) Leading to of the computer executable instructions performed by one or more computers or other calculating equipment Use and described herein embodiment is discussed below.Generally, program module include routine, Program, object, parts, data structure etc., it performs particular task or implements specific abstract number According to type.In various embodiments, the function of program module can be combined as required or divide Cloth.
By example but non-exclusive manner, computer usable medium can include Computer Storage Medium and communication media.Computer-readable storage medium include for such as computer-readable instruction, Any means of the storage of the information of data structure, program module or other data etc and technology Implement volatibility and non-volatile, deletable and unsuppressible medium.Computer Storage medium includes but not limited to random access storage device (RAM), read only memory (ROM). Electrically erasable ROM (EEPROM), flash memory or other memory technologies, CD drive (CD-ROM), Digital Versatile Disc (DVD) or other optical storages set Standby, cartridge, tape, disk memory or other magnetic memory devices, or can be used for Other media any of storage information needed.
Communication media can be presented as the modulation number at such as carrier wave or other transmission mechanisms etc Computer-readable instruction, data structure, program module or other data in the number of it is believed that, and Including any information delivery media.Term " modulated data signal " expression has one or more The signal of characteristic set or the signal being changed in the way of encoding information onto in the signal.Logical Crossing example but non-limiting way, communication media includes such as cable network or directly line connection etc Wire medium, and such as acoustics, radio frequency (RF), infrared and other wireless mediums etc Wireless medium.The combination of any of the above-described content should also be as being included in computer-readable medium In the range of.
As used herein, term " image " or " medical image " can be by interchangeably Using, and refer to the image created by imaging system, imaging system includes but not limited to x-ray Radiograph, X-ray computed tomography (CT) imaging, cone beam computed tomography image (CBCT), NMR (Nuclear Magnetic Resonance)-imaging (MRI), positron emission fault (PET) imaging, Single-photon emission computed tomography (SPET) imaging and ultrasonic (US) imaging.Doctor Treating image can be 2D image or 3D rendering.
In the following embodiments, describe for automatically generating the radioactivity photograph for patient The technology of phase imaging parameters.Embodiment includes for based on existing patient information and according to base Model in knowledge generates the method for one or more radiographic imaging parameters.
Exemplary radiation therapy and imager
Referring now to Fig. 1, depict according to the exemplary radiation therapy of a disclosed embodiment Diagram with imaging device 100.In one configuration, radiotherapy and imaging device 100 wrap Include supporting mechanism (such as, frame 101), include treating the radioactive source of head 103 (such as, Medical or clinical linear accelerator).In one embodiment, treatment head 103 be adapted with Receiving (such as, from electron gun) main electron beam, it is inciding (typically by height Z metal constitute) target material time generation is referred to as " bremsstrahlung photons (bremsstrahlung photon) " material, and thus generate photon beams, final contrary treatment Treatment source 105 is radiated.
In a further embodiment, multiple mechanical arms (such as, mechanical arm 107,108 and 109) Frame can be attached to and be coupled to second (diagnosis) radioactive source 111, and region detection Device plate 113 (being generally made up of the grid of single-point detector).According to some embodiments, additional Arm can be attached to the transmission gate area detector for receiving the radiation from treatment source 105 Plate 118.In a further embodiment, equipment 100 can include patient's couch 115.Real Executing the couch 115 in example is machinery couch, it is possible to mobile to change patient at couch On position.Radiotherapy and imaging device 100 may further include and be communicatively coupled Calculating equipment 117 is used for processing image and/or control and controlling equipment 100.Implement according to some Example, the radiation radiated from treatment source 105 and receive transmission gate detector plates 118 can To operate in the range of MV radiation (megavolt radiation), but dissipate from the second radioactive source 111 Cloth and the radiation that receives in area detector plate 113 can radiate at kV that (kilovolt is put Penetrate) in the range of operate.
In one embodiment, the end of frame 101 on patient's couch 115 it is positioned It is attached to for generating the treatment source 105 of (such as, for treatment or imaging purpose) radiation. Patient is positioned (generally lying on the back) on patient's couch 115.By by beam of radiation (example As, x-ray photon beam) it is transmitted through target volume and connects in area detector plate 113 Receive from the beam in source 111 or in detector plates 118, receive the beam from source 105 put Penetrate target volume (be generally positioned at patient subjects in or around).
According to an embodiment, diagnostic source 111 or treating radiation source 105 can be used respectively to tie Conjunction area detector 113 or area detector 118 obtain the image of target volume.Alternative In embodiment, x-ray detector and radioactive source can be used for diagnosis and and radiographic Field other application incoherent.In an embodiment, connect with for each radiographic image The corresponding data of the radiant that receives are stored by calculating equipment 117.Implement at another In example, the memorizer including calculating equipment 117 is substantially resistance to radiation, use substrate and/ Or logical method is known to those skilled in the art.
In other embodiments, system can not include radiotherapy equipment.But, system can To include radioactive source and imager.Such as, in other embodiments, system can include that x penetrates Line source and flat-panel detector.In a further embodiment, source and imager can be mounted or can Not to be installed on rotary frame (such as, for the rotary frame of CBCT).Although this Embodiment described in literary composition will include generation and the use of X-ray (photon) beam, but should Working as understanding, alternative is very suitable for other particles and the generation of corresponding beam of particles and makes With.These alternatives can include but not limited to, electronics and electron beam;Proton and matter Sub-beam;And ion and ion beams.
According to embodiment of the disclosure, before next-door neighbour's therapeutic process, radiographic imaging parameters The imaging being generated for the registration for patient (that is, location) and perform.According to determine Optimization can be advised or imaging parameters is pre-selected.Can be by patient information classification to guide and putting The selection of penetrating property photographing imaging parameter is for optimization.Such as, the patient about weight in patients believes Breath, the material (such as metal) occurred, want optimised content (such as, for child's The optimization of dosage, the cancer wherein induced is dangerous, in contrast to the image comparison for soft tissue Degree (it requires bigger radiological dose)) all can be included into the factor that imaging parameters generates. Can according to region interested (such as, if target area is bone structure, then can be only (due to the higher contrast for bone structure, therefore required relatively low for location bone structure Radiological dose) optimize the imaging being performed) and optimization to set up the registration of patient.Or, If target area is soft tissue, the biggest radiological dose is necessary.
According to embodiment of the disclosure, some radiographic imaging parameters of equipment 100 is permissible It is automatically calibrated (or alternatively, being proposed) to produce or to emphasize some of generated image Quality.These parameters can include such as, changes intensity (such as, the source voltage of photon beams And/or source electric current) or physical dimension (such as, angle or track), and/or area detector 113 or the position of area detector 118.Several picture gets parms and can include source and/or inspection Survey device position, orientation and/or track, scanning track, sectors type select (such as, half Sector or complete sector), and the position of couch 115.Extraly, radiation can be controlled The beam pulse length in source.In an aspect, can automatically select (or alternatively, build View) imaging and/or match pattern.Imaging parameters can include such as: to capture static volume or The determination of the sequence of multiple volumes (such as, 4D-CBCT);Numeral X-ray tomographic Combination (DTS) sets;CBCT sets;Determination (such as, imaging and the trouble of strobe sets The synchronization that person's anatomy moves);And image reconstruction parameter (such as, image slice thickness), As non-exhaustive list.
Image acquisition parameters can include such as: detector frame rate;Wave filter and Bao Yi (bowtie) select;For the setting of collimator sheet, and/or multi-blade collimator (multi-leaf Collimator, MLC) detector setting, such as, gain, details in a play not acted out on stage, but told through dialogues and pixel mixing (binning). Spirit and scope to other Image Processing parameter well known by persons skilled in the art Yu the disclosure Known.Additionally, according to embodiment of the disclosure, to external equipment (or multiple external equipment) Control and the imaging device communication of one or more functions.Exemplary external devices function includes: Gating;Succedaneum;Sport Administration equipment;And outside location equipment.Retouch the most further State the mode automatically generated for these and other radiographic imaging parameters, especially In the description of Fig. 2 to Fig. 5.
In an aspect, embodiment of the disclosure the employing whole trouble from therapeutic progresses in advance Person's data, in order to position image capturing to optimize radiographic imaging parameters for patient.Put Penetrating property photographing imaging parameter can include source dates (such as, source voltage) and image capture parameters Both (such as, frame rate).Depend on patient's case essence and it may be desirable to result, " optimize " optimization that can comprise one or more imaging parameters.
Referring now to Fig. 2, functional block diagram depicts the radiographic according to disclosure embodiment and becomes As parameter generates the exemplary configuration of system 200.Radiographic imaging parameters 200 includes reality Execute one or more Knowledge based engineering model 220 data processor 210, select module 225, Optimize module 230.Radiographic imaging parameters generates system 200 can be further Including input interface 235 and output interface 240.System 200 is wholly or partly carried out For software program, hardware logic, or a combination thereof.
Knowledge based engineering model 220 can include specialist system and/or physical model.Specialist system There is the knowledge of particular patient case, and depend on case, this system recommendations parameter preset. Such as, specialist system may be embodied as the data base of different case, and for each case, Unique parameter is designated.Each case in data base can include image pixel data, should Image pixel data includes anatomic information, the profile of such as anatomical structure, bone diameter, current Moisture, current fat content, the size of lung tissue, tumor's profiles etc..Normally, Specialist system is present in subsystem level and is i.e. exclusively used in the metal of special metal existence (such as Select to optimize the parameter of the imaging of metal), and for having the patient of metal implant, The metal being exclusively used in corresponding metal implant material can be used.Similarly, exist for respectively The soft tissue of type, expert for osseous tissue etc..The various combination of expert model can one Rise and select the imaging parameters for current case.
In comparison, physical model processes about the knowledge of certain material present in imaging volume (amount of bone that such as identifies in the image pixel data of case, the amount of metal, soft tissue Amount).Based on the information about the material in imaging volume, one or more physical models are permissible It is applied to determine radiograph imaging parameters (such as source voltage).
The combination using expert and physical model agreement is possible.In operation, existing trouble Person's data 205 (patient data i.e. existed before being positioned to as session) (preferably via Input interface 235) it is provided to radiographic imaging parameters generation system 200.Input is suffered from Person's data 205 can comprise the combination in any of parameter, and this parameter can actually affect radioactivity Photographing imaging and vector or other data structure can be organized as.Patient data 205 can Including various information, such as: patient records (such as age, disease type);Radiotherapy Plan;Treatment plan CT data in advance;Body region (such as head, breast for treatment Portion, pelvis);Image purpose and/or application, name just a few.To known to those skilled in the art The specific information of other patients consistent with the spirit and scope of the disclosure.Based on patient data 205, the one or more imaging class for radiographic image are determined.One or many Individual imaging class can include the patient class's (such as pediatric patients, obese patient) wanting imaging, And want the anatomic region (such as head, chest, pelvis) of imaging.Normally, imaging class Can not be designated so that it is being optimally generating the radiograph imaging parameters for patient Aspect is had any different.That is, pediatric patients should have the imaging protocol different from adult, and same The image (it is likely to mobile at image device) of sample ground chest may require that with head image not Same agreement.
The determination of imaging class (or multiple classification) makes it possible to select one or more radiation Line photographing imaging parameter, to be optimized for image, is performed this selection by selecting module 225. According to embodiment of the disclosure, select module 225 can automatically select one or more radiation Line photographing imaging parameter.Select module 225 be additionally configured to identify and select one or more based on The model of knowledge, based on patient data 205 and determined by imaging class, selected based on The model of knowledge is for determining the imaging protocol being suitable to current case.Selected is one or more Radiograph parameter is quilt according to selected Knowledge based engineering model (such as expert module) Process, in order to generating the value for selected radiograph imaging parameters, it is output as (many Individual) imaging parameters 215.
Selective emission line photographing imaging parameter and Knowledge based engineering model can be transparent to user, example Such as treatment plan person or practitioner, in order to need not manually select.Alternatively, as described herein (such as accompanying drawing 3 and Fig. 4), manually select for process some radiograph imaging Parameter is consistent with the spirit and scope of the disclosure with Knowledge based engineering model.In certain embodiments, This system can include user interface (such as input interface 235 and output interface 240), its Allow user to carry out constriction one or more radiograph imaging by the constraint that user limits to join Number, the patient data considered and the Knowledge based engineering model used.Alternatively, this system Parameter can be limited so that user only can select (according to plan knowledge by determined by system) Value in a certain scope.Alternatively, this system can be with proposed parameter (such as based on illustrating head The planning data of scanning, this system can produce the radiograph corresponding with head protocols and become As parameter).In an embodiment, this system 200 can " off-line " be implemented, and determines conjunction Suitable imaging parameters can realize before patient treatment.
Arrive as recognized by those skilled in the art, the disclosure be not limited to determine imaging class and / or any mechanism of suitable Knowledge based engineering model based on patient data or criterion.This selection Based on the similarity between patient data 205 and specialist system, and/or can be included in based on knowing Physical model in the model 220 known.This selection the most only can be selected based on maximum comparability Select an imaging class (or Knowledge based engineering model), according to selected similarity measurement That of the highest similarity of having there is patient data 205.Alternatively, this selection is all right Based on a certain acceptable similarity level, such as selected imaging class (or knowledge based Model) number can be different, wherein there are all imaging class of sufficiently high similarity (or Knowledge based engineering model) is chosen.Such as, bone coupling is often executed in advance Patient in treatment is positioned to picture.Mating for bone, soft tissue contrast is not particular importance, Therefore the Knowledge based engineering model being based only upon an expert model (or physical model) can be made Selecting, this Knowledge based engineering model includes substantially reducing radiological dose only to obtain the figure of bone The agreement of picture.
Single Knowledge based engineering model 220 can be derived from has some models to cover zones of different Clinic, or can be developed by radiological installation supplier, or can come in some clinics Share.This model can be from by facing the open source literature data of sick bed practitioner submission or facing sick bed number According to acquisition.
Radiograph imaging parameters generates
With reference now to accompanying drawing 3, flow chart 300 is described for based on existing patient information next life Become one or more radiographic imaging parameters of the radiographic image for patient The embodiment of method.Method 300 may be embodied as system, such as the system 200 of diagram in Fig. 2. Step 305-330 describes according to description in the flow chart 300 of various embodiments described herein The illustrative steps of process.In an embodiment, flow chart 300 is implemented as being stored in computer Computer executable instructions in computer-readable recording medium.
In step 305, receiving patient information (such as patient data 205) in system, this is Under unified central planning be set to generate radiograph imaging parameters with by radiographic apparatus for patient Carry out imaging.Patient data can include various information, such as: patient's record (the such as age, Disease type);Patient measurements (such as body weight, height, from optical system measuring Body contour);Radiotherapy treatment planning;Treatment plan CT data in advance;Body for treatment Body region (such as head, chest, pelvis);Image purpose and/or application, name just a few. Spirit and scope to other patient specific informations well known by persons skilled in the art Yu the disclosure Consistent.
Upon receipt of patient data, determine that the patient information received belongs to the most in the step 310 In one or more imaging class.As described herein, imaging class can include being become The type (such as, pediatric patients, obese patient) of the patient of picture, and solution to be imaged Cut open region (such as head, chest, pelvis).Normally, imaging class can be designated and make Obtain it to have any different in terms of the radiograph imaging parameters of patient in optimum generation.That is, youngster Section patient should have and the different imaging protocol of adult, and image (its of similarly chest It is likely to mobile at image device) may require that the agreement different from head image.
Make Knowledge based engineering model (such as Knowledge based engineering model 220) in step 315 Selection, this selection based on determine in step 310 based on imaging class.As described herein, Knowledge based engineering model can include specialist system and/or physical model.Knowledge based engineering (multiple) Model can be chosen automatically, and could be for the expert model example of particular subsystem If radiograph imaging parameters optimization is for the soft tissue of imaging, or for osseous tissue etc.. Alternatively or additionally, KBS Knowledge Based System, based on physical model, is wherein becoming about material Knowledge is there is in volume (amount of such as bone, the amount of metal, the amount etc. of soft tissue).Multiple Expert model and physical model can be chosen, and the combination of expert and physical model also with this Disclosed spirit and scope are consistent.According to embodiment of the disclosure, select Knowledge based engineering mould Type can be automatic, or alternatively the user of this system can perform to manually select (such as Via input interface 235).
In step 320, select one or more radiographic imaging parameters, wherein (multiple) Imaging class determined by the use of radiographic imaging parameters selects.There is some questions meeting shadow Ring the image quality and imaging parameters used.These include the structure of surrounding target image volume (such as bone, the high-load of soft tissue, such as pelvis area).Additionally, the expection of experimenter Motion (due to such as breathe) picture quality and collection, and acquisition mode can be affected.Right In some target area, select imaging parameters with extension sweep radius such as head, The image mode (the most entirely fanning pattern) with small radii can be used, and for pelvis, Expect the bigger visual field (the most partly fanning pattern).
According to embodiment of the disclosure, selective emission line photographing imaging parameter includes that user is mutual (such as via input interface 235) so that user is specifically worth and can be used generation imaging Parameter.Such as, user can formulate for the particular value of one or more imaging parameters or value Scope, other imaging parameters are generated while considering (multiple) parameter value that user specifies.
In step 325, selected radiograph imaging parameters according to one or more based on The model of knowledge and be processed for (multiple) radiograph that optimization step 320 selects Imaging parameters.Knowledge based engineering model is used for determining for one or more radiographic imagings The value of parameter, especially from the radiographic imaging parameters of step 320.Such as, for The image of chest, it is assumed that having the motion of chest, the most therefore specialist system can determine whether to include using 4D-CBCT (it considers respiratory movement) and/or the radiographic imaging of gating (gating) Parameter.That is, in order to make the minimised of patient moving, process is suffered from by Knowledge based engineering model Person's data are to generate the shortest imaging protocol.On the contrary, Knowledge based engineering model may indicate that Use gating, gather image, as long as such as patient is at maximum sucting stage.If image is to suffer from Person's head, the most different agreements can be selected by Knowledge based engineering model/be advised.
In the case of physical model, affected radiographic imaging parameters can be imaging Device frame rate, wave filter/Bao Yi (bowie) selection, source current/voltage etc..Implement at some In example, specialist system can determine the parameter (such as gating, 4D-CBCT etc.) of some classification, And physical model affects frame rate etc., as mentioned above.The combination of specialist system and physical model can For determining a set of parameter being generated.
In step 330, output is generated for selected radiographic imaging parameters Value.In an embodiment, for each radiographic imaging parameters is generated in step 315 Individual value.In an embodiment, generate the scope of the value for each radiographic imaging parameters, Or generate the scope of the value selecting number for multiple radiographic imaging parameters.According to Embodiment of the disclosure, value (or scope of value) can be the value of suggestion, or they are permissible It is automatically applied to imaging system (such as radiographic apparatus and imaging system).According to enforcement Example, value can be the value got rid of.
With reference now to accompanying drawing 4, flow chart 400 is described to generate the radiograph figure for patient The embodiment of the method for one or more radiographic imaging parameters of picture, including selecting alternatively Select the subset of existing patient information by the Knowledge based engineering models treated selected.Process 400 Including the optional user selection to some imaging parameters value, other program parameters refer to about user Fixed value and be generated.Step 405-455 describes and includes according to various embodiments described herein Flow chart 400 in the illustrative steps of process described.In one embodiment, flow chart 400 are stored in computer-readable medium.
In step 405, receive existing patient data.Patient data can include various letter Breath, such as: patient records (such as age, disease type);Patient measurements is (such as Body weight, height, body contour according to optical system measuring);Radiotherapy treatment planning;In advance Treatment plan CT data;Body region (such as head, chest, pelvis) for treatment; Image purpose and/or application, name just a few.Special to other patients well known by persons skilled in the art Determine information consistent with the spirit and scope of the disclosure.
In step 410, it is determined whether the patient data only consideration received in step 405 Subset.If it is not, then process proceeds to what step 420 and considering received in step 405 All patient datas.If it is, process proceeds to step 415, wherein select by process 400 The subset of the patient data considered.This selection can be by the operator of the system performing process 400 Such as make via input interface 235.It is alternatively possible to this selection predetermined, and The subset being pre-selected of patient data can be provided.Such as, patient data is one or more Classification can be identified for subset and select (such as patient's record and radiotherapy treatment planning), and Other can be identified as to ignore (such as image purpose and patient are measured).By this way, The relative importance of the different aspect (such as classification) of patient data can be by practitioner or reality Execute any user instruction of the system of process 400.
Once it is determined that for the patient data considered, just determine one or more one-tenth in step 425 As classification.As described herein, imaging class can include the type (example of patient to be imaged As, pediatric patients, obese patient), and anatomic region to be imaged (such as head, Chest, pelvis).Normally, imaging class can be designated so that it is for patient The radiograph imaging parameters aspect of good generation is had any different.
In step 430, it is determined whether manually select Knowledge based engineering model (or multiple mould Type).If it is not, then process proceeds to step 440, wherein occur to one or more based on Automatically selecting of the model of knowledge.If it is, process continues in step 435, wherein select Specific Knowledge based engineering model (or multiple model), it will be used for processing from step 415 or the patient data of step 420.Such as, Knowledge based engineering model could be for specific The expert model of subsystem such as optimizes the radiation for imaging soft tissue or osseous tissue etc. Property photographing imaging parameter.Alternatively or additionally, KBS Knowledge Based System is based on physical model, Wherein about material in imaging volume (amount of such as bone, the amount of metal, the amount etc. of soft tissue) Present in knowledge.Multiple expert models and physical model can be chosen, and expert and thing The combination of reason model is also consistent with the spirit and scope of the disclosure.In an embodiment, selection can Such as to be made via input interface 235 by the operator of the system of execution process 400.Standby Selection of land, select can based on such as about particular historical practitioner knowledge and location image quilt The disease of the patient that planning is used for predefines.
Optional step 445 includes one or more imaging parameters (such as via input interface 235) User select so that the value that user specifies can be used.In one aspect, given imaging Its of the imaging parameters that the value that the user of parameter specifies makes process 400 generate about user to specify His imaging parameters (in step 455).As non-restrictive example, full fan image capture mode Instruction manual (due to the scanning of such as cervical region) can make process 400 generate around entirely fanning constraint Other imaging parameters, cause the source specified/detector orientation and scanning track.
Follow selection specific Knowledge based engineering (multiple) model, in step 450, patient's number It is processed according to according to selected Knowledge based engineering (multiple) model.In step 455, one Individual or multiple radiographic imaging parameters are generated.The various combination of specialist system can be common Select the radiographic imaging parameters for patient.According to embodiment of the disclosure, from step 455 imaging parameters generated are the suggestions (such as via output interface 240) presenting to user. (multiple) imaging parameters of suggestion can be confirmed by the user, or alternatively, proposed imaging Parameter can change to, from the value of suggestion, the value that user specifies.(multiple) imaging parameters of suggestion The value (such as in the source of 30 degree of orientations) specified, or the scope (example for value can be rendered as Source electric current as at 60-80mA).
Embodiment of the disclosure and can be understood by using exemplary imaging case.An example In, for youngster (such as pediatric cases), be suitable to optimize radiographic imaging parameters and make The radiological dose that must reduce is delivered.The imaging parameters being suitable to select in this case is relatively low source Voltage and the setting of relatively low source electric current.Additionally, shorter beam pulse length can be automatic Be chosen (or being proposed in certain embodiments).If higher soft tissue contrast quilt (such as by practitioner) indicates, then the optimization of these radiographic imaging parameters can include The increase of these parameter values one or more.
In one example, for obese patient, can make image parameter select and optimize with Image is avoided to block.Block the target imaging volume appeared in less than 100% to be successfully imaged In the case of.From the patient data 205 of the plan CT including patient, it is known that patient Body weight, body contour etc..Patient data 205 is included in the body weight of statement in patient's record, with And the information about the body part that will be imaged.These may be used for estimating to be divided into body The required dosage of picture.It is likely to such as include Mobile sickbed (such as by selection and optimization Sick bed 115) parameter avoid the stage.Alternatively or additionally, detector (such as detects Device 113 and/or detector 118) can be moved for changing imaging volume.The detection reduced Device moves to cause and gathers image more quickly, because the volume of imaging can be reduced. On the contrary, moving detector allows more volume imaging, cost is to expend the more time.Attached Adding ground, the sick bed 115 to then machinery sick bed, patient can be moved around to be placed on Optimal location.Therefore the volume of imaging can be changed via imaging parameters, this imaging parameters bag Include that detector moves, sick bed moves and detector moves the combination moved with sick bed.
Another exemplary case relates to indicating the treatment plan of sectional therapy (such as according to patient's number According to 205).Often, treatment is segmented into some segmentations.Such as, full therapeutic scheme can be by Resolving into 30 segmentations so that for the dosage of whole 30 units, every segmentation has one (1) Dosage unit.Each segmentation can perform therefore for 30 segmentations in given sky, Treatment can complete in 30 days.For the treatment plan of segmentation, required by dose delivery Accuracy depends on the degree on division number.For the segmentation (highly segmentation) of big number, Owing to can there is the generation that more radiation delivers, each single radiation delivery is reduced, and accompanies Accuracy for delivering can be relaxed with the need.If on the contrary, using little segmentation, then Each segmentation has a larger dose, and need in the dose delivery of target area adjoint more Big accuracy.This means that therapeutic imaging is affected the most in advance: when using more During few segmentation, more time and/or larger dose can be used for placing image, and when using During more segmentation, less time and/or lower dosage can be used for placing image.According to enforcement Example, the parameter being input to system 200 includes it can being those tolerances for imaging dosage.
The function of the system and method for the disclosure is to provide and prevents image error, such as due to operation The image exposure of person's mistake is excessive.If operator is applied with too many dosage (such as works as largest body Long-pending when not occurring, it is applied with the dosage for maximum volume), then image can be exposed excessively. Knowledge from the volume being imaged of patient data 205 makes it possible to the spy for this image Determine to guide on dosage range.Can put on the dosage applied according to embodiment of the disclosure Put restriction over-exposed/under-exposed to avoid.
Exemplary computer device
As Fig. 5 presents, the example system bag that disclosure embodiment can be implemented thereon Include general purpose computing system environment, such as calculate system 500.In its most basic configuration, Calculating system 500 generally includes at least one processing unit 501 and memorizer, and is used for passing Reach the address/data bus 509 (or other interfaces) of message.Depend on computing system environment Accurately configuration and type, memorizer can be volatibility (such as RAM502), non-volatile (such as ROM503, flash memory etc.) or the some combination of the two of property.Real at some Executing in example, memorizer is the most radiation-resistant, uses substrate well known by persons skilled in the art And/or logical method.
Calculating system 500 can also include that optional graphics subsystem 505 is for presenting by information in To computer user, such as by the display device in the attachment connected by video cables 511 Information is shown on 510.According to embodiment of the disclosure, graphics subsystem 505 can be by regarding Frequently cable 511 is directly coupled to display device 510.For controlling in computer system 500 The graphical user interface of the application of the medical linear accelerator performed can be such as at figure subsystem System 505 generates, and is displayed to user in display device 510.In an alternative embodiment, Display device 510 is desirably integrated into calculating system (such as kneetop computer or net book display surface Plate) in and do not require video cables 511.
Additionally, calculating system 500 can also have additional feature/function.Such as, calculate The storage device (removable and/or non-removable) that system 500 can also include adding include but It is not limited to, disk or CD or tape.Such additional memorizer is set by data storage It is illustrated in Figure 5 for 507.Computer-storage media includes being implemented in for storing all Any side such as the information of computer-readable instruction, data structure, program module or other data Volatibility in method or technology and non-volatile, the removable and medium of non-removable. RAM 502, ROM 503 and data storage devices 507 are all computer-storage media Example.
In an embodiment, computer system 500 includes for performing each side according to the disclosure The treatment of process, wherein instruction can be stored in RAM 502, ROM 503 and/or data On memory devices 504.Such as, computer system 500 can include radiographic imaging Parameter generates instruction 513, wherein according to embodiment of the disclosure, and radiographic imaging parameters Generate instruction 513 to comprise so that computer system 500 performs to generate for from existing patient's letter Breath automatically generates process (the such as process of the value of one or more radiographic imaging parameters 300,400) instruction.
Computer system 500 also includes optional alphanumeric input equipment 506, optionally Mouse control or guiding equipment 507, and one or more signal communication interface (input/output Equipment, such as NIC) 509.Optional alphanumeric input equipment 506 is permissible Message or command selection is passed on to central processing unit 501.Optional mouse control or the equipment of guiding 507 are coupled to for passing on input message or the bus of command selection to central processing unit 501 509.Signal communication interface (input-output apparatus) 509 being also coupled to bus 509 is permissible It it is serial port.Communication interface 509 can also include wireless communication mechanism.Use communication interface 509, computer system 500 can be via communication network (such as the Internet or Intranet (example Such as LAN)) it is communicably coupled to other computer systems, or data (example can be received Such as digital television signal).
Although so that architectural feature and/or the specific language of method action are described this theme, It will be appreciated that the theme limited in the following claims is not necessarily limited to specific spy Levy or features described above.On the contrary, special characteristic and actions described above are described as reality Execute the exemplary forms of claim.

Claims (15)

1. generate a computer implemented method for radiograph imaging parameters, described method Including:
Receive the patient information relevant with the radiographic image for patient;
Imaging class is determined based on the patient information received;
Imaging class determined by use selects at least one Knowledge based engineering model;
Imaging class determined by use becomes from multiple radiographs of radiographic apparatus As parameter selects at least one radiograph imaging parameters;
The patient information received according to described Knowledge based engineering models treated is for being optimized to A few selected radiograph parameter;And
Export the value of at least one selected radiograph imaging parameters.
Computer implemented method the most according to claim 1, wherein said patient information Based at least one in the following: treatment plan imaging session data;Patient health record; Radiotherapy treatment planning;Treatment plan computed tomography image parameter in advance;The body region of described patient Territory.
Computer implemented method the most according to claim 1, wherein said knowledge based Model include at least one in specialist system and physical model.
Computer implemented method the most according to claim 1, wherein said multiple radiation Line photographing imaging parameter includes: radiographic apparatus imaging pattern;Image capture parameters;Several What image acquisition parameter;The body region of described patient;Radiographic apparatus source voltage and putting At least one in the electric current of radiographic apparatus source;At the equipment outside radiographic apparatus Control operation.
Computer implemented method the most according to claim 1, wherein said output valve bag Include the recommended value for selected radiograph imaging parameters.
6. embody a non-volatile computer readable storage medium storing program for executing for instruction, described instruction by When processing equipment performs so that described processing equipment execution following methods:
Receive the patient information relevant with the radiographic image for patient;
Imaging class is determined based on the patient information received;
Imaging class determined by use selects at least one Knowledge based engineering model;
Imaging class determined by use becomes from multiple radiographs of radiographic apparatus As parameter selects at least one radiograph imaging parameters;
The patient information received according to described Knowledge based engineering models treated is for optimizing institute State at least one selected radiograph parameter;And
Export the value of at least one selected radiograph imaging parameters.
Non-volatile computer readable storage medium storing program for executing the most according to claim 6, Qi Zhongsuo State patient information based at least one in the following: treatment plan imaging session data;Suffer from Person's health records;Radiotherapy treatment planning;Treatment plan computed tomography image parameter in advance;Institute State the body region of patient.
Non-volatile computer readable storage medium storing program for executing the most according to claim 6, Qi Zhongsuo State multiple radiograph imaging parameters to include: radiographic apparatus imaging pattern;Image is caught Obtain parameter;The geometric orientation of image capturing;The body region of described patient;Radiograph sets At least one in standby source voltage and radiographic apparatus source electric current;At radiographic apparatus The control operation of outside equipment.
Non-volatile computer readable storage medium storing program for executing the most according to claim 8, Qi Zhongsuo State output valve to include being restricted at least one selected radiograph imaging parameters described The scope of value.
Non-volatile computer readable storage medium storing program for executing the most according to claim 6, wherein Described Knowledge based engineering model includes multiple Knowledge based engineering model, and the plurality of based on knowing Described Knowledge based engineering model in the model known is automatically selected and receives for processing Patient information.
11. 1 kinds of radiotherapy equipments, including:
Multiple radioactive sources;
Multiple imagers, for receiving radiation from the plurality of radioactive source, and are configured to make a living Become to represent the data of the target image including multiple anatomical structure;And
Calculating equipment, is configured to access the trouble relevant with the radiographic image for patient Person's information, described calculating equipment is configured to determine imaging class based on described patient information, And imaging class determined by based on selects Knowledge based engineering model, and from described radiation Multiple radiograph imaging parameters of therapeutic equipment select at least one radiograph to become As parameter, described radiograph imaging parameters selects based on described imaging class, wherein said Calculating equipment is configured to process received patient's letter according to described Knowledge based engineering model Cease for optimizing and generating at least one selected radiograph imaging parameters described Value.
12. radiotherapy equipments according to claim 11, wherein said patient information base At least one in the following: treatment plan imaging session data;Patient health record; Radiotherapy treatment planning;Treatment plan computed tomography image parameter in advance;The body region of described patient Territory.
13. radiotherapy equipments according to claim 11, wherein said Knowledge based engineering Model includes at least one in the following: specialist system, and physical model.
14. radiotherapy equipments according to claim 11, wherein said multiple imagings are joined Number include in the following at least one: the source voltage of the plurality of radioactive source and described The source electric current of multiple radioactive sources.
15. radiotherapy equipments according to claim 11, wherein said multiple imagings are joined Number includes the image capture parameters of the plurality of imager.
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