CN105800589A - Glassy carbon and artificial trachea prepared thereby - Google Patents
Glassy carbon and artificial trachea prepared thereby Download PDFInfo
- Publication number
- CN105800589A CN105800589A CN201610311124.0A CN201610311124A CN105800589A CN 105800589 A CN105800589 A CN 105800589A CN 201610311124 A CN201610311124 A CN 201610311124A CN 105800589 A CN105800589 A CN 105800589A
- Authority
- CN
- China
- Prior art keywords
- parts
- titanium dioxide
- polyacrylonitrile
- artificial trachea
- vitreous carbon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/22—Materials or treatment for tissue regeneration for reconstruction of hollow organs, e.g. bladder, esophagus, urether, uterus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Transplantation (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Inorganic Chemistry (AREA)
- Composite Materials (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Materials For Medical Uses (AREA)
Abstract
The invention discloses glassy carbon and an artificial trachea prepared thereby. The glassy carbon for the artificial trachea is prepared from the following raw materials in parts by weight: 40-100 parts of polyacrylonitrile, 30-40 parts of polysiloxane, 80-100 parts of cellulose acetate, 20-30 parts of polyvinyl chloride, 10-20 parts of tricalcium phosphate, 90-100 parts of potassium oxide, 20-70 parts of titanium dioxide and 60-90 parts of polydimethylsiloxane. The preparation method comprises the following steps: mixing the polyacrylonitrile, the polysiloxane, the cellulose acetate, the polyvinyl chloride, the tricalcium phosphate, the potassium oxide, the titanium dioxide and the polydimethylsiloxane evenly, melting, cooling and molding; and carrying out carbonization treatment on an anaerobic medium, and heating the product to 2,000-3,000 DEG C for 1-2 hours. The glassy carbon is relatively good in biological stability; the elasticity modulus is 22-24GPa; the fatigue strength is 93-100MPa; the compressive strength is 680-700MPa; the biological aging resistance is high.
Description
Technical field
The present invention relates to biological medicine Material Field, particularly relate to a kind of vitreous carbon for artificial trachea and preparation method thereof.
Background technology
Vitreous carbon (GC) is a kind of novel material with carbon element. vitreous carbon, have that air-tightness and good conductivity, coefficient of thermal expansion be little, quality hard be easily polished into minute surface, chemical inertness, there is the features such as higher hydrogen overpotential, be therefore applicable to do the working electrode material of electrochemistry and electroanalysis.It is referred to as vitreous carbon because of its port pattern glass similar to architectural feature, is almost invented by the Davison of Britain and Japan Yamada for 1962 simultaneously.There is the characteristics such as little, high temperature resistant, the impermeabilisation of density due to vitreous carbon so that it is have been widely used at numerous areas such as chemical industry, metallurgical industry, electronics industry, biological engineering.
Vitreous carbon has that air-tightness and good conductivity, coefficient of thermal expansion be little, quality hard be easily polished into minute surface, chemical inertness, there is the features such as higher hydrogen overpotential, be therefore applicable to do the working electrode material of electrochemistry and electroanalysis.The form of electrode has bar-shaped, disk, rotating circular disk, rotating ring disk electrode (r.r.d.e) etc..The potential range that glassy carbon electrode is suitable for is wider, both can study inorganic matter in nagative potential district, it is also possible to the many organic redox reaction occurred in positive potential district of research.Matrix is made, it is also possible to prepare hydrargyrum membrane glass-carbon electrode and chemically modified electrode with it.Electrode to carry out surface finish, chemical treatment and electrochemical treatments before use.
Summary of the invention
The present invention is directed to the deficiencies in the prior art, it is provided that a kind of vitreous carbon for artificial trachea and preparation method thereof, vitreous carbon resistance to biodeterioration can be strong.
In order to solve above-mentioned technical problem, the present invention by the following technical solutions:
For the vitreous carbon of artificial trachea, including the raw material of following parts by weight: polyacrylonitrile 40～100 parts, polysiloxanes 30～40 parts, cellulose acetate 80～100 parts, polrvinyl chloride 20～30 parts, tricalcium phosphate 10～20 parts, potassium oxide 90～100 parts, titanium dioxide 20～70 parts, polydimethylsiloxane 60～90 parts.
As to further improvement of the present invention, for the vitreous carbon of artificial trachea, including the raw material of following parts by weight: polyacrylonitrile 70 parts, polysiloxanes 35 parts, cellulose acetate 90 parts, polrvinyl chloride 25 parts, tricalcium phosphate 15 parts, potassium oxide 95 parts, titanium dioxide 50 parts, polydimethylsiloxane 70 parts.
As to further improvement of the present invention, the particle diameter of titanium dioxide is 40～150 μm.
As to further improvement of the present invention, the molecular weight of polyacrylonitrile is 10000～20000.
The preparation method that present invention also offers a kind of vitreous carbon for artificial trachea.
The preparation method of a kind of vitreous carbon for artificial trachea, comprises the following steps: polyacrylonitrile, polysiloxanes, cellulose acetate, polrvinyl chloride, tricalcium phosphate, potassium oxide, titanium dioxide, polydimethylsiloxane mix homogeneously, fusing, cools down molding；Carrying out carbonization treatment in without oxygen medium, then heat to 2000～3000 DEG C of reaction 1～2h, the carbonization treatment time is 20～50min.
A kind of artificial trachea, it adopts above-mentioned vitreous carbon to make.
Beneficial effect: the vitreous carbon of prior art causes wherein metal ion to organize diffusion towards periphery due to bioenvironmental corrosion, the vitreous carbon of the present invention can be applied as artificial trachea, not perishable diffusion, it is because the vitreous carbon biological stability after carbonization treatment better, elastic modelling quantity is 22～24GPa, fatigue strength is 93～100MPa, and comprcssive strength is 680～700MPa, and resistance to biodeterioration can be strong.
Detailed description of the invention
Below in conjunction with specific embodiment, the invention will be further described.
Embodiment 1
For the vitreous carbon of artificial trachea, including the raw material of following parts by weight: polyacrylonitrile 70 parts, polysiloxanes 35 parts, cellulose acetate 90 parts, polrvinyl chloride 25 parts, tricalcium phosphate 15 parts, potassium oxide 95 parts, titanium dioxide 50 parts, polydimethylsiloxane 70 parts.
The particle diameter of titanium dioxide is 100 μm.
The molecular weight of polyacrylonitrile is 15000.
The preparation method of a kind of vitreous carbon for artificial trachea, comprises the following steps: polyacrylonitrile, polysiloxanes, cellulose acetate, polrvinyl chloride, tricalcium phosphate, potassium oxide, titanium dioxide, polydimethylsiloxane mix homogeneously, fusing, cools down molding；In without oxygen medium, carry out carbonization treatment, then heat to 2500 DEG C of reaction 1.5h.
The carbonization treatment time is 40min.
Embodiment 2
For the vitreous carbon of artificial trachea, including the raw material of following parts by weight: polyacrylonitrile 40 parts, polysiloxanes 30 parts, cellulose acetate 80 parts, polrvinyl chloride 20 parts, tricalcium phosphate 10 parts, potassium oxide 90 parts, titanium dioxide 20 parts, polydimethylsiloxane 60 parts.
The particle diameter of titanium dioxide is 40 μm.
The molecular weight of polyacrylonitrile is 10000.
The preparation method of a kind of vitreous carbon for artificial trachea, comprises the following steps: polyacrylonitrile, polysiloxanes, cellulose acetate, polrvinyl chloride, tricalcium phosphate, potassium oxide, titanium dioxide, polydimethylsiloxane mix homogeneously, fusing, cools down molding；In without oxygen medium, carry out carbonization treatment, then heat to 2000 DEG C of reaction 1h.
The carbonization treatment time is 20min.
Embodiment 3
For the vitreous carbon of artificial trachea, including the raw material of following parts by weight: polyacrylonitrile 100 parts, polysiloxanes 40 parts, cellulose acetate 100 parts, polrvinyl chloride 30 parts, tricalcium phosphate 20 parts, potassium oxide 100 parts, titanium dioxide 70 parts, polydimethylsiloxane 90 parts.
The particle diameter of titanium dioxide is 150 μm.
The molecular weight of polyacrylonitrile is 20000.
The preparation method of a kind of vitreous carbon for artificial trachea, comprises the following steps: polyacrylonitrile, polysiloxanes, cellulose acetate, polrvinyl chloride, tricalcium phosphate, potassium oxide, titanium dioxide, polydimethylsiloxane mix homogeneously, fusing, cools down molding；In without oxygen medium, carry out carbonization treatment, then heat to 3000 DEG C of reaction 2h.
The carbonization treatment time is 50min.
Embodiment 4
For the vitreous carbon of artificial trachea, including the raw material of following parts by weight: polyacrylonitrile 90 parts, polysiloxanes 33 parts, cellulose acetate 85 parts, polrvinyl chloride 22 parts, tricalcium phosphate 12 parts, potassium oxide 93 parts, titanium dioxide 30 parts, polydimethylsiloxane 70 parts.
The particle diameter of titanium dioxide is 60 μm.
The molecular weight of polyacrylonitrile is 12000.
The preparation method of a kind of vitreous carbon for artificial trachea, comprises the following steps: polyacrylonitrile, polysiloxanes, cellulose acetate, polrvinyl chloride, tricalcium phosphate, potassium oxide, titanium dioxide, polydimethylsiloxane mix homogeneously, fusing, cools down molding；In without oxygen medium, carry out carbonization treatment, then heat to 2200 DEG C of reaction 1.2h.
The carbonization treatment time is 25min.
Embodiment 5
For the vitreous carbon of artificial trachea, including the raw material of following parts by weight: polyacrylonitrile 80 parts, polysiloxanes 38 parts, cellulose acetate 97 parts, polrvinyl chloride 28 parts, tricalcium phosphate 18 parts, potassium oxide 98 parts, titanium dioxide 60 parts, polydimethylsiloxane 80 parts.
The particle diameter of titanium dioxide is 130 μm.
The molecular weight of polyacrylonitrile is 18000.
The preparation method of a kind of vitreous carbon for artificial trachea, comprises the following steps: polyacrylonitrile, polysiloxanes, cellulose acetate, polrvinyl chloride, tricalcium phosphate, potassium oxide, titanium dioxide, polydimethylsiloxane mix homogeneously, fusing, cools down molding；In without oxygen medium, carry out carbonization treatment, then heat to 2800 DEG C of reaction 1.8h.
The carbonization treatment time is 40min.
Comparative example 1
Identical with embodiment 1, difference is in that: be omitted in without the step carrying out carbonization treatment in oxygen medium.
Performance test
Measuring the properties of product of embodiment and comparative example, result is in Table 1.
Table 1
Conclusion: the vitreous carbon biological stability after carbonization treatment is better, will not as the vitreous carbon of prior art owing to bioenvironmental corrosion causes wherein metal ion to organize diffusion towards periphery, the vitreous carbon elastic modelling quantity of the present invention is 22～24GPa, fatigue strength is 93～100MPa, comprcssive strength is 680～700MPa, and resistance to biodeterioration can be strong.
Claims (2)
1. for the preparation method of the vitreous carbon of artificial trachea, it is characterized in that, vitreous carbon is by the raw material of following parts by weight: polyacrylonitrile 40～100 parts, polysiloxanes 30～40 parts, cellulose acetate 80～100 parts, polrvinyl chloride 20～30 parts, tricalcium phosphate 10～20 parts, potassium oxide 90～100 parts, titanium dioxide 20～70 parts, polydimethylsiloxane 60～90 parts；
The particle diameter of titanium dioxide is 40～150 μm；
Described preparation method, comprises the following steps: polyacrylonitrile, polysiloxanes, cellulose acetate, polrvinyl chloride, tricalcium phosphate, potassium oxide, titanium dioxide, polydimethylsiloxane mix homogeneously, fusing, cools down molding；In without oxygen medium, carry out carbonization treatment, then heat to 2000～3000 DEG C of reaction 1～2h.
2. an artificial trachea, it is characterised in that it adopts the vitreous carbon that the preparation method described in claim 1 prepares to make.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610311124.0A CN105800589B (en) | 2014-11-10 | 2014-11-10 | A kind of vitreous carbon and its manufactured artificial trachea |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410625934.4A CN104445142B (en) | 2014-11-10 | 2014-11-10 | Vitreous carbon for artificial trachea and preparation method thereof |
| CN201610311124.0A CN105800589B (en) | 2014-11-10 | 2014-11-10 | A kind of vitreous carbon and its manufactured artificial trachea |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410625934.4A Division CN104445142B (en) | 2014-11-10 | 2014-11-10 | Vitreous carbon for artificial trachea and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105800589A true CN105800589A (en) | 2016-07-27 |
| CN105800589B CN105800589B (en) | 2017-11-24 |
Family
ID=56456735
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610311124.0A Active CN105800589B (en) | 2014-11-10 | 2014-11-10 | A kind of vitreous carbon and its manufactured artificial trachea |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105800589B (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5921512A (en) * | 1982-07-26 | 1984-02-03 | Mitsubishi Pencil Co Ltd | Manufacture of thin glassy carbon plate |
| JPH01286962A (en) * | 1988-05-10 | 1989-11-17 | Kao Corp | Vitreous carbon composite material and production thereof and sliding part therefrom |
| JPH01320208A (en) * | 1988-06-21 | 1989-12-26 | Showa Denko Kk | Production of molded glassy carbon plate |
| JPH0255427A (en) * | 1988-08-20 | 1990-02-23 | Matsushita Electric Ind Co Ltd | Squelch circuit |
| JPH09255427A (en) * | 1996-03-26 | 1997-09-30 | Tokai Carbon Co Ltd | Carbon heater |
-
2014
- 2014-11-10 CN CN201610311124.0A patent/CN105800589B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5921512A (en) * | 1982-07-26 | 1984-02-03 | Mitsubishi Pencil Co Ltd | Manufacture of thin glassy carbon plate |
| JPH01286962A (en) * | 1988-05-10 | 1989-11-17 | Kao Corp | Vitreous carbon composite material and production thereof and sliding part therefrom |
| JPH01320208A (en) * | 1988-06-21 | 1989-12-26 | Showa Denko Kk | Production of molded glassy carbon plate |
| JPH0255427A (en) * | 1988-08-20 | 1990-02-23 | Matsushita Electric Ind Co Ltd | Squelch circuit |
| JPH09255427A (en) * | 1996-03-26 | 1997-09-30 | Tokai Carbon Co Ltd | Carbon heater |
Non-Patent Citations (3)
| Title |
|---|
| 胡会利 等主编: "《电化学测量》", 31 August 2007, 国防工业出版社 * |
| 陈德敏: "生物陶瓷材料（二）", 《口腔材料器械杂志》 * |
| 龚敏 等: "改性酚醛树脂碳化制备玻璃碳的研究", 《四川轻化工学院学报》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105800589B (en) | 2017-11-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101880039B (en) | Composite film based on glassy carbon and graphene and preparation method thereof | |
| Luo et al. | Performance of two bacteria-based additives used for self-healing concrete | |
| Liang et al. | Formation of superhydrophobic cerium oxide surfaces on aluminum substrate and its corrosion resistance properties | |
| CN103774435A (en) | Preparation and application methods of carbon fiber mat surface antioxidation coating | |
| CN103992113B (en) | A kind of B 4c-ZrB 2the preparation method of diphase ceramic material | |
| CN101798076B (en) | Method for preparing composite thin plate based on glass carbon and carbon nanotube | |
| CN103882442A (en) | Stainless steel surface three-dimensional nanocarbon film and preparation method thereof | |
| CN106958053B (en) | A kind of preparation method of porous petroleum coke base carbon fibre | |
| CN105800589A (en) | Glassy carbon and artificial trachea prepared thereby | |
| CN104445142B (en) | Vitreous carbon for artificial trachea and preparation method thereof | |
| CN108325398A (en) | A kind of preparation method of pollution-resistant membrane material | |
| CN110723732B (en) | Preparation method of super-dispersed nano-diamond suspension | |
| CN116496103A (en) | High-strength low-density silicon carbide and preparation method and application thereof | |
| CN105399086B (en) | A kind of method that sodium chloride auxiliary prepares graphene perforated membrane | |
| CN108499372A (en) | A method of preparing high tenacity porous ceramic film support using microorganism | |
| Wang et al. | Preparation and characterization of dense graphite/glassy carbon composite coating for sealing application | |
| CN102924854B (en) | Teflon composite material and preparation method thereof | |
| Lang et al. | Preparation of YSZ porous ceramics with precise porosity control | |
| CN101164970B (en) | Multi-component silicon carbide ceramic with insert including charcoal fibre | |
| CN101164978B (en) | Silicon carbide ceramic composition containing silicon carbide whisker | |
| Hossain et al. | Corrosion behavior of silicon-based ceramics in alkaline and green solution | |
| CN101164975B (en) | Silicon carbide ceramic containing carbon fiber and sheet aluminum oxide embedded particles | |
| CN109970389A (en) | A kind of preparation method of Resbon tube | |
| Xu et al. | Fabrication and Polishing Performance of Diamond Self-Sharpening Gel Polishing Disk | |
| CN105842289A (en) | Metal oxide gas-sensitive sensing substrate material and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB03 | Change of inventor or designer information | ||
| CB03 | Change of inventor or designer information |
Inventor after: Hong Lanying Inventor before: Request for anonymity |
|
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20171026 Address after: A district 322200 in Zhejiang County of Pujiang Province town of Zheng Zheng Village 212 three Applicant after: Hong Lanying Address before: 213000 North District, Jiangsu, Changzhou Jin Ling North Road, Hohai University Applicant before: Wu Jie |
|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20180104 Address after: 300000 Tianjin Jixian County economic development zone and Tianjin Special Automobile Industrial Park Patentee after: Tianjin China boson new materials Co.,Ltd. Address before: A district 322200 in Zhejiang County of Pujiang Province town of Zheng Zheng Village 212 three Patentee before: Hong Lanying |