CN105785903A - Remote monitoring system for bioreactor - Google Patents
Remote monitoring system for bioreactor Download PDFInfo
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- CN105785903A CN105785903A CN201610191659.9A CN201610191659A CN105785903A CN 105785903 A CN105785903 A CN 105785903A CN 201610191659 A CN201610191659 A CN 201610191659A CN 105785903 A CN105785903 A CN 105785903A
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- bioreactor
- monitoring
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- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
- G05B19/00—Programme-control systems
- G05B19/02—Programme-control systems electric
- G05B19/04—Programme control other than numerical control, i.e. in sequence controllers or logic controllers
- G05B19/05—Programmable logic controllers, e.g. simulating logic interconnections of signals according to ladder diagrams or function charts
Abstract
The invention discloses a remote monitoring system for a bioreactor. The system comprises a bottom level monitoring sub system, a PLC programmable controller and a control client, wherein the bottom level monitoring sub system is arranged on the bioreactor and is used for monitoring a real-time reaction signal of the bioreactor, the PLC programmable controller is connected with the bottom level monitoring sub system, the reaction signal acquired in real time is transmitted by the bottom level monitoring sub system to the PLC programmable controller, the acquired reaction parameter signal is transmitted by the PLC programmable controller to an industrial control computer, the reaction parameter signal from the PLC programmable controller is processed and converted by the industrial control computer, the processed parameter data is sent to a network end, the control client can enter a browse page or is equipped with a monitoring APP, and various parameters of the bioreactor can be checked by a user through a browser or the APP of the control client. The system is convenient to use, requires no field monitoring and no filed operation carried out by a monitor and saves the time for an operator.
Description
Technical field
The present invention relates to biological respinse monitoring system regions, in particular for the monitoring of the numerical value such as pH, DO, temperature, mixing speed, pressure, weight, gas flow, revolution speed, be specifically related to bioreactor long distance control system.
Background technology
At present, conventional bioreactor, control system, rely primarily on PLC module and on-the-spot touch screen to realize control function, monitoring personnel are by the manipulation to touch screen human-computer interface, it is achieved checking and controlling each parameter of bioreactor.
Because bioreactor needs uninterruptedly operating in continuous many days 24 hours, and to the requirement that the precision and stability that control parameter have comparison high, thus it is frequently necessary to operation employee go to scene to check every certain time whether data normal;Or because the needs of culture process, it may be necessary to change certain culture parameters in certain time, for instance evening, temperature was controlled to be changed to 33 DEG C by 36.8 DEG C by 11 needs;This monitoring mode is extremely inconvenient, also increases the workload of policer operation personnel.And bioreactor is often positioned over clean area; in order to check that whether data are normal or do some fairly simple parameter change; operator needed to spend the longer time to carry out sterilizing before entering reaction zone; sometimes even delay one or two hour; very inconvenient; further, operator frequently enter reactor rest area and also strengthen pollution risk.
Summary of the invention
It is an object of the invention to the problem above overcoming prior art to exist, bioreactor long distance control system is provided, the present invention checks mainly as non-at-scene and control, connected by PLC network, and develop IE interface, cell phone software APP etc., make need to check accordingly that parameter is transmitted to network, by browser or mobile phone A PP software collection and show, the button that need to control or data are back to PLC accordingly, thus realizing place remote control function.
For realizing above-mentioned technical purpose, reaching above-mentioned technique effect, the present invention is achieved through the following technical solutions:
Bioreactor long distance control system, comprising:
Bottom Monitor And Control Subsystem, described bottom Monitor And Control Subsystem is arranged on bioreactor, is used for monitoring described bioreactor Real time response signal;
PLC, described PLC connects described bottom Monitor And Control Subsystem, the reaction signal transmission extremely described PLC that described bottom Monitor And Control Subsystem will obtain in real time, described PLC by obtain reaction signal through process and conversion after, obtaining the response parameter data of monitoring in real time, the response parameter obtained is transmitted to network-side by described PLC;
Controlling client, described control client can enter browsing pages or be provided with monitoring APP, and user checks the parameters of bioreactor by the browser of described control client or APP.
In a preferred embodiment of the present invention, farther including, described bottom Monitor And Control Subsystem includes:
Dissolved oxygen electrode, described dissolved oxygen electrode is for the dissolved oxygen in monitoring bio reactor;
PH electrode, described pH electrode is for obtaining pH signal real-time in bioreactor;
Temperature sensor, described temperature sensor is for obtaining temperature signal real-time in bioreactor;
Pressure transducer, described pressure transducer is for obtaining pressure signal real-time in bioreactor;
Weight sensor, described weight sensor is for obtaining weight signal real-time in biological inductor.
In a preferred embodiment of the present invention, farther including, described control client is computer, flat board or mobile phone.
In a preferred embodiment of the present invention, farther include, by described control client, user checks that the parameters of bioreactor includes:
Temperature, jacket temperature, pressure, capacity, gas flow, mixing speed, pan feeding pump speed, discharging pump speed in dissolved oxygen, pH, tank.
In a preferred embodiment of the present invention, farther include, by described control client, user checks that the step of bioreactor parameters includes:
S1 user opens browser or APP, input login account and password by described control client;
S2 system is to after login account and password authentification success, and pop-up dialogue box, according to the prompting of dialog box, user inputs IP address, clicks " confirmation " button;
The each parameter of bioreactor that in S4 and S3, the IP address of input is corresponding shows in real time.
The invention has the beneficial effects as follows:
Bioreactor system in one, the present invention is capable of off-site surveillane and controls function, this system is connected by PLC network, and develop IE interface, cell phone software APP etc., make to check that parameter is transmitted to network accordingly, by browser or mobile phone A PP software collection and show, the button that need to control or data are back to PLC accordingly, thus realizing place remote control function.
Two, the bioreactor system of the present invention is easy to use, and personnel are without on-site supervision and execute-in-place in monitoring, save the time for operation employee.
Three, the bioreactor monitoring system of the present invention uses PC and mobile phone all can realize monitoring, without height configuration equipment, reduce the cost being equipped with special purpose computer or other adnexa, and without placing other intermediate conversion computer or other adnexa, decrease space.
Described above is only the general introduction of technical solution of the present invention, in order to better understand the technological means of the present invention, and can be practiced according to the content of description, below with presently preferred embodiments of the present invention and coordinate accompanying drawing describe in detail as after.The specific embodiment of the present invention is shown in detail in by following example and accompanying drawing thereof.
Accompanying drawing explanation
In order to be illustrated more clearly that the technical scheme in embodiment of the present invention technology, the accompanying drawing used required in the description of embodiment technology will be briefly described below, apparently, accompanying drawing in the following describes is only some embodiments of the present invention, for those of ordinary skill in the art, under the premise not paying creative work, it is also possible to obtain other accompanying drawing according to these accompanying drawings.
Fig. 1 is the principle framework figure of the bioreactor long distance control system of the present invention.
Detailed description of the invention
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is only a part of embodiment of the present invention, rather than whole embodiments.Based on the embodiment in the present invention, the every other embodiment that those of ordinary skill in the art obtain under not making creative work premise, broadly fall into the scope of protection of the invention.
Embodiment
With reference to shown in Fig. 1, a kind of bioreactor long distance control system disclosed in the present embodiment, it mainly includes bottom Monitor And Control Subsystem, bottom monitoring controls subsystem, industrial PC, Internet network and controls client.
Above-mentioned bottom Monitor And Control Subsystem is really and is made up of some sensors or monitoring modular, and it is arranged on bioreactor, is used for monitoring above-mentioned bioreactor Real time response signal, collects the parameter signal that bioreactor is real-time.
It is PLC that the monitoring of above-mentioned bottom controls subsystem, above-mentioned PLC connects above-mentioned bottom Monitor And Control Subsystem, the reaction signal transmission extremely above-mentioned PLC that above-mentioned bottom Monitor And Control Subsystem will obtain in real time, the response parameter signal obtained is transmitted to industrial PC by above-mentioned PLC.
Above-mentioned industrial PC is the data processing centre of whole system, and the response parameter signal from above-mentioned PLC is carried out processing and changing by above-mentioned industrial PC, then sends supplemental characteristic to network-side.
Above-mentioned control client is really user and uses terminal, can be computer, flat board or personal mobile phone, above-mentioned control client can enter browsing pages or be provided with monitoring APP, and user checks the parameters of bioreactor by the browser of above-mentioned control client or APP.
In the present embodiment, by above-mentioned control client, user checks that the parameters of bioreactor includes: temperature, jacket temperature, pressure, capacity, gas flow, mixing speed, pan feeding pump speed, discharging pump speed in dissolved oxygen, pH, tank.
Therefore, above-mentioned bottom Monitor And Control Subsystem includes:
(1) dissolved oxygen electrode, above-mentioned dissolved oxygen electrode is for the dissolved oxygen in monitoring bio reactor.
(2) pH electrode, above-mentioned pH electrode is for obtaining pH signal real-time in bioreactor.
(3) temperature sensor, said temperature sensor is for obtaining temperature signal real-time in bioreactor.
(4) pressure transducer, above-mentioned pressure transducer is for obtaining pressure signal real-time in bioreactor.
(5) weight sensor, above-mentioned weight sensor is for obtaining weight signal real-time in biological inductor.
Mixing speed by the servomotor transmission of control signals of agitator, pan feeding pump speed and discharging pump speed also by its electric control gear transmission of control signals to monitoring system.
By above-mentioned control client, user checks that the step of bioreactor parameters includes:
S1 user opens browser or APP, input login account and password by above-mentioned control client;
S2 system is to after login account and password authentification success, and pop-up dialogue box, according to the prompting of dialog box, user inputs IP address, clicks " confirmation " button;
The each parameter of bioreactor that in S4 and S3, the IP address of input is corresponding shows in real time.
Bioreactor system in the present embodiment is capable of off-site surveillane and controls function, this system is connected by PLC network, and develop IE interface, cell phone software APP etc., make to check that parameter is transmitted to network accordingly, by browser or mobile phone A PP software collection and show, the button that need to control or data are back to PLC accordingly, thus realizing place remote control function.
The bioreactor system of the present embodiment is easy to use, and personnel are without on-site supervision and execute-in-place in monitoring, save the time for operation employee.
Bioreactor monitoring system in the present embodiment uses PC and mobile phone all can realize monitoring, without height configuration equipment, reduce the cost being equipped with special purpose computer or other adnexa, and without placing other intermediate conversion computer or other adnexa, decrease space.
Described above to the disclosed embodiments, makes professional and technical personnel in the field be capable of or uses the present invention.The multiple amendment of these embodiments be will be apparent from for those skilled in the art, and generic principles defined herein can without departing from the spirit or scope of the present invention, realize in other embodiments.Therefore, the present invention is not intended to be limited to the embodiments shown herein, and is to fit to the widest scope consistent with principles disclosed herein and features of novelty.
Claims (5)
1. bioreactor long distance control system, it is characterised in that comprising:
Bottom Monitor And Control Subsystem, described bottom Monitor And Control Subsystem is arranged on bioreactor, is used for monitoring described bioreactor Real time response signal;
PLC, described PLC connects described bottom Monitor And Control Subsystem, the reaction signal transmission extremely described PLC that described bottom Monitor And Control Subsystem will obtain in real time, the response parameter signal obtained is transmitted to industrial PC by described PLC;
Response parameter signal from described PLC is carried out processing and changing by described industrial PC, then sends supplemental characteristic to network-side;
Controlling client, described control client can enter browsing pages or be provided with monitoring APP, and user checks the parameters of bioreactor by the browser of described control client or APP.
2. bioreactor long distance control system according to claim 1, it is characterised in that described bottom Monitor And Control Subsystem includes:
Dissolved oxygen electrode, described dissolved oxygen electrode is for the dissolved oxygen in monitoring bio reactor;
PH electrode, described pH electrode is for obtaining pH signal real-time in bioreactor;
Temperature sensor, described temperature sensor is for obtaining temperature signal real-time in bioreactor;
Pressure transducer, described pressure transducer is for obtaining pressure signal real-time in bioreactor;
Weight sensor, described weight sensor is for obtaining weight signal real-time in biological inductor.
3. bioreactor long distance control system according to claim 1, it is characterised in that described control client is computer, flat board or mobile phone.
4. bioreactor long distance control system according to claim 3, it is characterised in that by described control client, user checks that the parameters of bioreactor includes:
Temperature, jacket temperature, pressure, capacity, gas flow, mixing speed, pan feeding pump speed, discharging pump speed in dissolved oxygen, pH, tank.
5. the bioreactor long distance control system according to claim 1-4 any one, it is characterised in that by described control client, user checks that the step of bioreactor parameters includes:
S1 user opens browser or APP, input login account and password by described control client;
S2 system is to after login account and password authentification success, and pop-up dialogue box, according to the prompting of dialog box, user inputs IP address, clicks " confirmation " button;
The each parameter of bioreactor that in S4 and S3, the IP address of input is corresponding shows in real time.
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CN201610191659.9A CN105785903A (en) | 2016-03-30 | 2016-03-30 | Remote monitoring system for bioreactor |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106156544A (en) * | 2016-08-04 | 2016-11-23 | 天信和(苏州)生物科技有限公司 | It is applied to the real-time online process data preservation processing system that cell is cultivated |
CN107505897A (en) * | 2017-08-30 | 2017-12-22 | 滁州市西控电子有限公司 | A kind of multi-functional raising chamber's control system |
CN107661893A (en) * | 2017-11-02 | 2018-02-06 | 上海埃松气流控制技术有限公司 | A kind of intelligent vent cabinet system |
CN110365833A (en) * | 2018-04-09 | 2019-10-22 | 山东克朗生物装备有限公司 | Fermentation Engineering biology equips cell phone application monitoring system |
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CN101022385A (en) * | 2007-03-29 | 2007-08-22 | 王忠伟 | Interconnection network-based long-distance monitering system and monitoring method |
CN102732423A (en) * | 2012-06-29 | 2012-10-17 | 江南大学 | Biological fermentation controller |
CN104932434A (en) * | 2014-03-17 | 2015-09-23 | 杨悦 | Automatic control system for sewage treatment membrane bioreactor |
CN104995568A (en) * | 2012-09-14 | 2015-10-21 | 通用电气医疗集团生物科学公司 | Methods and apparatus to implement flexible bioreactor control systems |
CN205035377U (en) * | 2015-10-09 | 2016-02-17 | 上海海洋大学 | But remote control cultivates flat photobioreactor of little algae |
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2016
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Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101022385A (en) * | 2007-03-29 | 2007-08-22 | 王忠伟 | Interconnection network-based long-distance monitering system and monitoring method |
CN102732423A (en) * | 2012-06-29 | 2012-10-17 | 江南大学 | Biological fermentation controller |
CN104995568A (en) * | 2012-09-14 | 2015-10-21 | 通用电气医疗集团生物科学公司 | Methods and apparatus to implement flexible bioreactor control systems |
CN104932434A (en) * | 2014-03-17 | 2015-09-23 | 杨悦 | Automatic control system for sewage treatment membrane bioreactor |
CN205035377U (en) * | 2015-10-09 | 2016-02-17 | 上海海洋大学 | But remote control cultivates flat photobioreactor of little algae |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
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CN106156544A (en) * | 2016-08-04 | 2016-11-23 | 天信和(苏州)生物科技有限公司 | It is applied to the real-time online process data preservation processing system that cell is cultivated |
CN107505897A (en) * | 2017-08-30 | 2017-12-22 | 滁州市西控电子有限公司 | A kind of multi-functional raising chamber's control system |
CN107661893A (en) * | 2017-11-02 | 2018-02-06 | 上海埃松气流控制技术有限公司 | A kind of intelligent vent cabinet system |
CN110365833A (en) * | 2018-04-09 | 2019-10-22 | 山东克朗生物装备有限公司 | Fermentation Engineering biology equips cell phone application monitoring system |
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Application publication date: 20160720 |