CN105769603A - Micro-injection foundation and preparation method thereof - Google Patents
Micro-injection foundation and preparation method thereof Download PDFInfo
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- CN105769603A CN105769603A CN201610117724.3A CN201610117724A CN105769603A CN 105769603 A CN105769603 A CN 105769603A CN 201610117724 A CN201610117724 A CN 201610117724A CN 105769603 A CN105769603 A CN 105769603A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 11
- 238000000520 microinjection Methods 0.000 title abstract 5
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 22
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims abstract description 22
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 22
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims abstract description 22
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 claims abstract description 21
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 claims abstract description 21
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims abstract description 11
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims abstract description 11
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims abstract description 11
- BAWFJGJZGIEFAR-NNYOXOHSSA-N NAD zwitterion Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-N 0.000 claims abstract description 11
- 229960005070 ascorbic acid Drugs 0.000 claims abstract description 11
- 235000010323 ascorbic acid Nutrition 0.000 claims abstract description 11
- 239000011668 ascorbic acid Substances 0.000 claims abstract description 11
- 239000001110 calcium chloride Substances 0.000 claims abstract description 11
- 229910001628 calcium chloride Inorganic materials 0.000 claims abstract description 11
- 229920002674 hyaluronan Polymers 0.000 claims abstract description 11
- 229960003160 hyaluronic acid Drugs 0.000 claims abstract description 11
- 229910052943 magnesium sulfate Inorganic materials 0.000 claims abstract description 11
- 235000019341 magnesium sulphate Nutrition 0.000 claims abstract description 11
- 229910000403 monosodium phosphate Inorganic materials 0.000 claims abstract description 11
- 235000019799 monosodium phosphate Nutrition 0.000 claims abstract description 11
- 229950006238 nadide Drugs 0.000 claims abstract description 11
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 claims abstract description 11
- 239000011607 retinol Substances 0.000 claims abstract description 11
- 229960003471 retinol Drugs 0.000 claims abstract description 11
- 235000020944 retinol Nutrition 0.000 claims abstract description 11
- 239000011780 sodium chloride Substances 0.000 claims abstract description 11
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 claims abstract description 11
- 230000003712 anti-aging effect Effects 0.000 claims abstract description 10
- 239000005515 coenzyme Substances 0.000 claims abstract description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 30
- 239000006071 cream Substances 0.000 claims description 29
- 239000002537 cosmetic Substances 0.000 claims description 24
- 229940079593 drug Drugs 0.000 claims description 24
- 239000003814 drug Substances 0.000 claims description 24
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 claims description 20
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims description 20
- 239000001060 yellow colorant Substances 0.000 claims description 14
- WTFXARWRTYJXII-UHFFFAOYSA-N iron(2+);iron(3+);oxygen(2-) Chemical compound [O-2].[O-2].[O-2].[O-2].[Fe+2].[Fe+3].[Fe+3] WTFXARWRTYJXII-UHFFFAOYSA-N 0.000 claims description 10
- SZVJSHCCFOBDDC-UHFFFAOYSA-N iron(II,III) oxide Inorganic materials O=[Fe]O[Fe]O[Fe]=O SZVJSHCCFOBDDC-UHFFFAOYSA-N 0.000 claims description 10
- 239000004408 titanium dioxide Substances 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- RJZNPROJTJSYLC-LLINQDLYSA-N (4s)-4-acetamido-5-[[(2s)-1-[[(2s)-1-[[(2s)-5-amino-1-[[(2s)-1-[[(2s)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-car Chemical compound OC(=O)CC[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O RJZNPROJTJSYLC-LLINQDLYSA-N 0.000 claims description 9
- 108010006338 acetyl-glutamyl-glutamyl-methionyl-glutaminyl-arginyl-argininamide Proteins 0.000 claims description 9
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 9
- 239000003086 colorant Substances 0.000 claims description 5
- 239000001062 red colorant Substances 0.000 claims description 5
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims description 4
- 238000001816 cooling Methods 0.000 claims description 4
- 239000012467 final product Substances 0.000 claims description 4
- 238000005374 membrane filtration Methods 0.000 claims description 4
- 238000002156 mixing Methods 0.000 claims description 4
- 238000007789 sealing Methods 0.000 claims description 4
- 230000001954 sterilising effect Effects 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 4
- 229960002685 biotin Drugs 0.000 claims description 2
- 235000020958 biotin Nutrition 0.000 claims description 2
- 239000011616 biotin Substances 0.000 claims description 2
- 239000011148 porous material Substances 0.000 abstract description 12
- 230000000694 effects Effects 0.000 abstract description 7
- 238000005516 engineering process Methods 0.000 abstract description 2
- 230000003203 everyday effect Effects 0.000 abstract description 2
- 238000002347 injection Methods 0.000 abstract description 2
- 239000007924 injection Substances 0.000 abstract description 2
- 238000007920 subcutaneous administration Methods 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract 2
- DFPAKSUCGFBDDF-ZQBYOMGUSA-N [14c]-nicotinamide Chemical compound N[14C](=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-ZQBYOMGUSA-N 0.000 abstract 1
- 229960002713 calcium chloride Drugs 0.000 abstract 1
- 229960002668 sodium chloride Drugs 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 230000008676 import Effects 0.000 description 4
- 230000002354 daily effect Effects 0.000 description 3
- 230000008901 benefit Effects 0.000 description 2
- 210000002615 epidermis Anatomy 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- -1 nicotiamide Chemical compound 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 238000007670 refining Methods 0.000 description 2
- 240000003864 Ulex europaeus Species 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/23—Sulfur; Selenium; Tellurium; Compounds thereof
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- A—HUMAN NECESSITIES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/29—Titanium; Compounds thereof
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- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
- A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
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- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
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- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
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- A61K8/67—Vitamins
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- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
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- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/02—Preparations containing skin colorants, e.g. pigments
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
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- Biochemistry (AREA)
- Molecular Biology (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to micro-injection foundation and a preparation method thereof.The micro-injection foundation comprises more than 20 raw and auxiliary materials such as nicotinamide adenine dinucleotide, nicotinamide, calcium chloride, sodium chloride, coenzyme, tryptophan, ascorbic acid, tryptophan, antiaging tetrapeptide, hexapeptide, retinol, magnesium sulfate, sodium dihydrogen phosphate and hyaluronic acid, and the raw and auxiliary materials are prepared into an injection.The skin beautifying effect is achieved through the subcutaneous micro-injection technology, the effect of shrinkage of enlarged pores can be achieved, a large amount of time is saved for a user, the complexity of makeup every day is saved, the foundation can be kept for 2-4 weeks through micro-injection of the foundation, and the complexity of foundation applying is saved.
Description
Technical field
Present invention relates particularly to a kind of foundation cream, more particularly, it relates to a kind of micro-note foundation cream and preparation method thereof.
Background technology
Foundation cream is the basis of dressing, the foundation cream of powdery texture is modal, it is coated in and seems soft natural on the face, it it is the selection of daily adornment, its type is also a lot, Chinese patent CN104688590A discloses the ventilative foundation cream of a kind of moisturizing, Chinese patent CN104069014A vanishing cream/foundation emulsion disclosing a kind of controllable color change and preparation method thereof etc., but, daily foundation cream in use also has a lot of problems, conventional foundation cream can make skin pore thick owing to being coated on the face, produce pox pox, simultaneously also very inconvenient in daily life, often as some big activities and destroy its dressing, it is also required to all make up every day simultaneously, and stop over the substantial amounts of time, for this, it is very necessary for finding a kind of good foundation cream.
Summary of the invention
In order to solve the problems referred to above that invention prior art exists, originally providing a kind of micro-note foundation cream, this foundation cream reaches the effect of skin Caring by the mode of micro-note, and can also pore refining, save the substantial amounts of time.
The present invention can be achieved through the following technical solutions:
A kind of micro-note foundation cream, its formula includes nicotinamide adenine dinucleotide 4-8 part, nicotiamide 4-8 part, calcium chloride 4-8 part, sodium chloride 4-8 part, biotin 4-8 part, tryptophan 4-8 part, ascorbic acid 4-8 part, retinol 4-8 part, tryptophan 4-8 part, anti-ageing four victory peptide 4-8 parts, Argireline 4-8 part, magnesium sulfate 4-8 part, sodium dihydrogen phosphate 4-8 part, hyaluronic acid 4-8 part and Federal Food, Drug and cosmetics accreditation colorant；
In the formula of above-mentioned micro-note foundation cream, described Federal Food, Drug and cosmetics accreditation colorant include water, glycerol, black iron oxide, yellow iron oxide, Federal Food, Drug and cosmetics yellow colorant, Federal Food, Drug and cosmetics reddish yellow colorant, titanium dioxide；
The formula of above-mentioned micro-note foundation cream, specifically include nicotinamide adenine dinucleotide 5 parts, nicotiamide 5 parts, 5 parts of calcium chloride, 5 parts of sodium chloride, coenzyme 5 parts, tryptophan 5 parts, 5 parts of ascorbic acid, retinol 6 parts, tryptophan 6 parts, anti-ageing four victory peptide 6 parts, Argireline 6 parts, 6 parts of magnesium sulfate, sodium dihydrogen phosphate 6 parts, hyaluronic acid 6 parts, and 15 parts of water, glycerol 5 parts, black iron oxide 1 part, yellow iron oxide 1 part, Federal Food, Drug and cosmetics 5 are or/and 0.4 part of No. 6 yellow colorants, Federal Food, Drug and cosmetics 30 are or/and 0.4 part of No. 40 red colorants, titanium dioxide 0.2 part.
Above-mentioned micro-note foundation cream, its preparation method includes:
(1) nicotinamide adenine dinucleotide 5g, nicotiamide 5g, calcium chloride 5g, sodium chloride 5g, coenzyme 5g, tryptophan 5g, ascorbic acid 5g, tryptophan 6g, anti-ageing four victory peptide 6g, Argireline 6g, retinol 6g, magnesium sulfate 6g, sodium dihydrogen phosphate 6g, hyaluronic acid 6g ground and mixed, are taken standby；
(2), water intaking 15g, glycerol 5g mixes, add black iron oxide 1g, yellow iron oxide 1g, Federal Food, Drug and No. 5 and No. 6 yellow colorant 0.4g of cosmetics, Federal Food, Drug and cosmetics No. 30 and No. 40 red colorant 0.4g, titanium dioxide 0.2g and carry out ultrasonic 5 minutes, solution for standby；
(3), the carrying out in (1) and (2) step is mixed in 60～70 DEG C of water-baths and stirs to entirely molten, it is cooled to room temperature, with 0.22 μm of membrane filtration after mixing, stablize under the airtight condition of 70-80 DEG C 2-4 hour, then at room temperature airtight cooling, sub-bottle fill, sealing, sterilizing, to obtain final product.
In the preparation method of above-mentioned micro-note foundation cream, described is stably carry out in airtight reactor.
The invention have the benefit that and the invention provides a kind of micro-note foundation cream, by micro-note injection, the effect of beauty treatment can not only be played, and can also pore refining, it is simple to the maintenance of dressing is not destroyed.
For making the object, technical solutions and advantages of the present invention clearly, technical scheme will be described in detail below.Obviously, described embodiment is only a part of embodiment of the present invention, rather than whole embodiments.Based on the embodiment in the present invention, other embodiments all that those of ordinary skill in the art are obtained under the premise not making creative work, broadly fall into the scope that the present invention protects；
According to the present invention, the pore dia of the mankind is typically in 100-200 microns, mean diameter granule near pore dia easily blocks pore, and therefore the mean diameter of the foundation cream granule of the present invention is passed through after grinding is dissolved less than mankind's pore dia, is not resulted in the blocking of pore by micro-note；
According to the present invention, by micro-note foundation cream, can keeping 2 weeks to 4 weeks, thus having saved the substantial amounts of time, owing to it is subcutaneous micro-note, not resulting in injury.
According to the present invention, choose 5 18-38 year the women of corse sweat pore, it has been carried out micro-note foundation cream of 3 months, it was found that its skin pore has the effect reduced, illustrate the present invention foundation cream can not only life-time service, and pore is shunk and has certain effect.
Embodiment 1,
Prescription: nicotinamide adenine dinucleotide 5 parts, nicotiamide 5 parts, 5 parts of calcium chloride, 5 parts of sodium chloride, coenzyme 5 parts, tryptophan 5 parts, 5 parts of ascorbic acid, tryptophan 6 parts, anti-ageing four victory peptide 6 parts, Argireline 6 parts, retinol 6 parts, 6 parts of magnesium sulfate, sodium dihydrogen phosphate 6 parts, hyaluronic acid 6 parts, and 15 parts of water, glycerol 5 parts, black iron oxide 1 part, yellow iron oxide 1 part, Federal Food, Drug and 0.4 part of No. 5 and No. 6 yellow colorants of cosmetics, Federal Food, Drug and 0.4 part of No. 30 and No. 40 red colorants of cosmetics, titanium dioxide 0.2 part；
Preparation method: take nicotinamide adenine dinucleotide, nicotiamide, calcium chloride, sodium chloride, coenzyme, tryptophan, ascorbic acid, tryptophan, anti-ageing four victory peptides, Argireline, retinol, magnesium sulfate, sodium dihydrogen phosphate, hyaluronic acid ground and mixed standby；Water intaking, glycerol mixes, and adds black iron oxide, yellow iron oxide, Federal Food, Drug and cosmetics yellow colorant, Federal Food, Drug and cosmetics reddish yellow colorant, titanium dioxide carry out ultrasonic 5 minutes, solution for standby；Above-mentioned spares carries out being mixed in stirring in 60～70 DEG C of water-baths and, to entirely molten, is cooled to room temperature, with 0.22 μm of membrane filtration after mixing, stablize under the airtight condition of 70-80 DEG C 2-4 hour, then at room temperature airtight cooling, sub-bottle fill, sealing, sterilizing, to obtain final product；
Using method: use high precise and tiny note instrument (import frequency and be adjusted to 80 Hess), import skin, micro-note
Syringe needle must become 90 degree of right angles with imported parts；When micro-note foundation cream being imported simultaneously, it is ensured that be directed under epidermis 0.2-0.3mm.
Embodiment 2, prescription: nicotinamide adenine dinucleotide 5 parts, nicotiamide 4 parts, 6 parts of calcium chloride, 5 parts of sodium chloride, coenzyme 4 parts, tryptophan 5 parts, 5 parts of ascorbic acid, tryptophan 6 parts, anti-ageing four victory peptide 5 parts, Argireline 7 parts, retinol 4 parts, 4 parts of magnesium sulfate, sodium dihydrogen phosphate 8 parts, hyaluronic acid 6 parts, and 15 parts of water, glycerol 5 parts, black iron oxide 1 part, yellow iron oxide 1 part, Federal Food, Drug and 0.4 part of No. 5 yellow colorants of cosmetics, Federal Food, Drug and 0.4 part of No. 40 cosmetics redness colorants, titanium dioxide 0.2 part；
Preparation method: take nicotinamide adenine dinucleotide, nicotiamide, calcium chloride, sodium chloride, coenzyme, tryptophan, ascorbic acid, tryptophan, anti-ageing four victory peptides, Argireline, retinol, magnesium sulfate, sodium dihydrogen phosphate, hyaluronic acid ground and mixed standby；Water intaking, glycerol mixes, and adds black iron oxide, yellow iron oxide, Federal Food, Drug and cosmetics yellow colorant, Federal Food, Drug and cosmetics reddish yellow colorant, titanium dioxide carry out ultrasonic 5 minutes, solution for standby；Above-mentioned spares carries out being mixed in stirring in 60～70 DEG C of water-baths and, to entirely molten, is cooled to room temperature, with 0.22 μm of membrane filtration after mixing, stablize under the airtight condition of 70-80 DEG C 2-4 hour, then at room temperature airtight cooling, sub-bottle fill, sealing, sterilizing, to obtain final product；
Using method: use high precise and tiny note instrument (import frequency and be adjusted to 80 Hess), import skin, micro-note
Syringe needle must become 90 degree of right angles with imported parts；When micro-note foundation cream being imported simultaneously, it is ensured that be directed under epidermis 0.2-0.3mm.
Claims (5)
1. a micro-note foundation cream, it includes nicotinamide adenine dinucleotide 4-8 part, nicotiamide 4-8 part, calcium chloride 4-8 part, sodium chloride 4-8 part, biotin 4-8 part, tryptophan 4-8 part, ascorbic acid 4-8 part, tryptophan 4-8 part, anti-ageing four victory peptide 4-8 parts, Argireline 4-8 part, retinol 4-8 part, magnesium sulfate 4-8 part, sodium dihydrogen phosphate 4-8 part, hyaluronic acid 4-8 part and Federal Food, Drug and cosmetics accreditation colorant.
2. micro-note foundation cream according to claim 1, it is characterised in that: described Federal Food, Drug and cosmetics accreditation colorant include water, glycerol, black iron oxide, yellow iron oxide, Federal Food, Drug and cosmetics yellow colorant, Federal Food, Drug and cosmetics reddish yellow colorant, titanium dioxide.
3. micro-note foundation cream according to claim 2, it is characterized in that: include nicotinamide adenine dinucleotide 5 parts, nicotiamide 5 parts, 5 parts of calcium chloride, 5 parts of sodium chloride, coenzyme 5 parts, tryptophan 5 parts, 5 parts of ascorbic acid, tryptophan 6 parts, anti-ageing four victory peptide 6 parts, Argireline 6 parts, retinol 6 parts, 6 parts of magnesium sulfate, sodium dihydrogen phosphate 6 parts, hyaluronic acid 6 parts, and 15 parts of water, glycerol 5 parts, black iron oxide 1 part, yellow iron oxide 1 part, Federal Food, Drug and cosmetics 5 are or/and 0.4 part of No. 6 yellow colorants, Federal Food, Drug and cosmetics 30 are or/and 0.4 part of No. 40 red colorants, titanium dioxide 0.2 part.
4. a micro-note foundation cream, its preparation method includes:
(1) nicotinamide adenine dinucleotide 5g, nicotiamide 5g, calcium chloride 5g, sodium chloride 5g, coenzyme 5g, tryptophan 5g, ascorbic acid 5g, retinol 6g, magnesium sulfate 6g, sodium dihydrogen phosphate 6g, hyaluronic acid 6g ground and mixed, are taken standby；
(2), water intaking 15g, glycerol 5g mixes, add black iron oxide 1g, yellow iron oxide 1g, Federal Food, Drug and No. 5 No. 6 yellow colorant 0.4g of cosmetics, Federal Food, Drug and cosmetics No. 30 and No. 40 red colorant 0.4g, titanium dioxide 0.2g and carry out ultrasonic 5 minutes, solution for standby；
(3), the carrying out in (1) and (2) step is mixed in 60～70 DEG C of water-baths and stirs to entirely molten, it is cooled to room temperature, with 0.22 μm of membrane filtration after mixing, stablize under the airtight condition of 70-80 DEG C 2-4 hour, then at room temperature airtight cooling, sub-bottle fill, sealing, sterilizing, to obtain final product.
5. the preparation method of micro-note foundation cream according to claim 4, it is characterised in that: described stablizing carries out in airtight reactor.
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| CN201610117724.3A CN105769603A (en) | 2016-03-02 | 2016-03-02 | Micro-injection foundation and preparation method thereof |
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| CN110934768A (en) * | 2019-12-25 | 2020-03-31 | 深圳市龙格生技术有限公司 | Nicotinamide ribose derivative cosmetic raw material and application thereof in cosmetics |
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| CN110934768A (en) * | 2019-12-25 | 2020-03-31 | 深圳市龙格生技术有限公司 | Nicotinamide ribose derivative cosmetic raw material and application thereof in cosmetics |
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Application publication date: 20160720 |