CN105769193A - Electrode device for measuring scalp and skull impedance in animal experiments - Google Patents

Electrode device for measuring scalp and skull impedance in animal experiments Download PDF

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Publication number
CN105769193A
CN105769193A CN201610108656.4A CN201610108656A CN105769193A CN 105769193 A CN105769193 A CN 105769193A CN 201610108656 A CN201610108656 A CN 201610108656A CN 105769193 A CN105769193 A CN 105769193A
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electrode
scalp
skull
urceolus
cap
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CN105769193B (en
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董秀珍
杨琳
徐灿华
付峰
代萌
尤富生
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Fourth Military Medical University FMMU
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Fourth Military Medical University FMMU
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/053Measuring electrical impedance or conductance of a portion of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/053Measuring electrical impedance or conductance of a portion of the body
    • A61B5/0538Measuring electrical impedance or conductance of a portion of the body invasively, e.g. using a catheter

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

The invention discloses an electrode device for measuring scalp and skull impedance in animal experiments, and belongs to the technical field of impedance measurement.Split structures of an electrode cap, an electrode core and an electrode outer barrel are integrated into a whole, the electrode core is arranged in the electrode outer barrel, the upper portion of the electrode outer barrel is sleeved with the electrode cap, the wiring way in an electrode is simplified, and elements in a scalp electrode circuit and a skull electrode circuit are tightly combined, so that influences of external disturbance on measurement results are reduced, scalp measurement and skull measurement can be achieved, disassembly, assembly and cleaning work are convenient due to the split structures, and measurement accuracy can be effectively ensured; in addition, a spring is arranged between a skull electrode pad layer and the electrode cap, the height of the skull electrode pad layer can be adjusted through the spring, it can be ensured that the skull electrode pad layer is connected with the electrode core, and it is ensured that the skull electrode makes direct and tight contact with the electrode pad layer.The electrode device is easy and convenient to use and easy to operate, and provides a reliable guarantee for smoothly carrying out animal experiments.

Description

A kind of electrode assembly for zoopery impedance bioelectrical measurement scalp and skull
Technical field
The invention belongs to impedance bioelectrical measurement technical field, be specifically related to a kind of electrode assembly for zoopery impedance bioelectrical measurement scalp and skull.
Background technology
Different human body tissue has different cellularity, so different human body tissue has different electrical impedance.And normal structure is under pathological state, its cellularity also can change, and therefore, same be organized under normal physiological and pathological state and have different electrical impedance equally.Generally, by being placed with electrode at human body surface, and apply safe exciting current to human body, then measure tested position electrical impedance, human normal physiology and pathological state can be judged, and then the prevention and control for the detection of human body organ dysfunction and disease provides reference information.
Zoopery is the only stage which must be passed by that impedance bioelectrical measurement technology is pushed to clinical practice.Impedance bioelectrical measurement technology can be applied to the safety of human body by zoopery, and feasibility and effectiveness are verified, and electrode is to carry out zooperal necessary device.Owing to laboratory animal and human body exist different, so body electrode is applied to zoopery and there is inconvenience, for instance, there is bigger difference in animal volume and human body, so the electrode in zoopery and the varying in size of electrode being applied to human body.It addition, for deeper hierarchical research impedance bioelectrical measurement technology, usually carry out the experiment of different purpose in zoopery, so, the electrode in zoopery needs the electrode of design difference in functionality.
Impedance bioelectrical measurement technology has important using value in cerebrovascular disease detection and monitoring.At present, the impedance bioelectrical measurement zoopery for brain is carried out in a large number, for the scalp electrode that brain uses, adopts the cup-shape electrode that diameter is less.But, in detection skull, the distribution of electric current is the normal experiment of checking impedance bioelectrical measurement technology, so we are required to the electrode being deep in skull, and cup-shape electrode cannot meet requirement.Therefore, in the zoopery carrying out impedance bioelectrical measurement, it is necessary to a kind of easy, efficacious scalp and skull electrode multipurpose electrode.
Summary of the invention
It is an object of the invention to provide a kind of electrode assembly for zoopery impedance bioelectrical measurement scalp and skull, this apparatus structure is reasonable in design, simple to operate, it is possible to be effectively improved the accuracy of measurement, provides reliable guarantee for carrying out zoopery smoothly.
The present invention is achieved through the following technical solutions:
A kind of electrode assembly for zoopery impedance bioelectrical measurement scalp and skull disclosed by the invention, including electrode cap, electrode cores and electrode urceolus;Electrode cores is arranged in electrode urceolus, and electrode cap is sleeved on above electrode urceolus;
Be provided with two contact conductor ports on electrode cap top, centre is skull contact conductor port, and outside is scalp electrode lead-in wire port;Electrode cap lower end is provided with skull electrode bed course, and skull contact conductor port is connected by skull contact conductor with skull electrode bed course, is provided with spring between electrode cap top and skull electrode bed course;Be provided with electrode cap scalp electrode bed course in electrode cap lower end, scalp electrode lead-in wire port is connected by electrode cap scalp electrode lead-in wire with electrode cap scalp electrode bed course;
Be provided with electrode urceolus scalp electrode bed course in electrode urceolus upper end, lower end is provided with scalp electrode, and scalp electrode is connected with electrode urceolus scalp electrode bed course by electrode urceolus scalp electrode lead-in wire;
When electrode urceolus is connected with electrode cap, electrode urceolus scalp electrode bed course is in close contact with electrode cap scalp electrode bed course.
Electrode urceolus top is provided with the screw thread adapted with electrode cap inner surface.
Electrode cores is threadingly attached in electrode urceolus.
Outside this electrode assembly, it is additionally provided with electrode fixed mount, and is formed around electrode draw-in groove at electrode fixed mount.
Electrode fixed mount is additionally provided with belt fixing device.
Skull contact conductor, electrode cap scalp electrode lead-in wire is all connected with impedance bioelectrical measurement device with electrode urceolus scalp electrode lead-in wire.
Electrode cap and electrode urceolus are made by lucite.
Skull electrode bed course and electrode cores are made by electric good conductor.
During scalp electrode measurement pattern, electrode cores lower end is positioned at electrode urceolus, and scalp electrode and scalp are fully contacted.
During skull electrode mode measurement, electrode cores lower end is positioned at outside electrode urceolus, regulates the electrode degree of depth in skull by electric rotating pole piece.
Compared with prior art, the present invention has following useful technique effect:
Electrode assembly for zoopery impedance bioelectrical measurement scalp and skull disclosed by the invention, employing discrete designs, by electrode cap, the separate structure of electrode cores and electrode urceolus integrates, electrode cores is made to be arranged in electrode urceolus, electrode cap is set in above electrode urceolus, and simplify the mode of connection in electrode, make combining closely of each element in scalp electrode circuit and skull telegraph circuit, thus reducing the external interference impact on measurement result, it is capable of the dual purpose of scalp and craniometry, the structure of discrete is easy to dismounting and cleaning, can effectively ensure that the accuracy of measurement.Meanwhile, having spring between skull electrode bed course and electrode cap, skull electronic pads layer height can be regulated by spring, it can be ensured that skull electrode bed course is connected with electrode cores, it is ensured that skull electrode and electrode bed course are directly in close contact.This device is easy to use, simple to operate, provides reliable guarantee for carrying out zoopery smoothly.
Further, electrode urceolus top is provided with the screw thread adapted with electrode cap inner surface, and electrode cores is positioned at electrode urceolus, is connected with electrode urceolus by screw thread, and electrode cores passes through screw thread scalable height in electrode urceolus.Meanwhile, adopt screw thread design conveniently to dismantle, and can guarantee that combining closely of each element in circuit.
Further, outside this electrode assembly, it is additionally provided with electrode fixed mount, fixes with electrode fixed mount, it is ensured that scalp electrode and scalp close contact, electrode cores and skull close contact.Electrode cores adopts tapping screw thread, and conveniently adjusted electrode is positioned at the degree of depth of skull.
Accompanying drawing explanation
Fig. 1 is the electrode assembly structural representation for zoopery impedance bioelectrical measurement scalp and skull disclosed by the invention;
Fig. 2-1 is the front view for zoopery impedance bioelectrical measurement scalp and the electrode cap of the electrode assembly of skull disclosed by the invention;
Fig. 2-2 is the top view for zoopery impedance bioelectrical measurement scalp and the electrode cap of the electrode assembly of skull disclosed by the invention;
Fig. 3-1 is the front view for zoopery impedance bioelectrical measurement scalp and the electrode urceolus of the electrode assembly of skull disclosed by the invention;
Fig. 3-2 is the top view for zoopery impedance bioelectrical measurement scalp and the electrode urceolus of the electrode assembly of skull disclosed by the invention;
Fig. 4-1 is the front view for zoopery impedance bioelectrical measurement scalp and the electrode cores of the electrode assembly of skull disclosed by the invention;
Fig. 4-2 is the top view for zoopery impedance bioelectrical measurement scalp and the electrode cores of the electrode assembly of skull disclosed by the invention;
Fig. 5-1 is the front view for zoopery impedance bioelectrical measurement scalp and the fixed mount of the electrode assembly of skull disclosed by the invention;
Fig. 5-2 is the top view for zoopery impedance bioelectrical measurement scalp and the fixed mount of the electrode assembly of skull disclosed by the invention.
Wherein, 101 is scalp electrode lead-in wire port;102 go between for electrode cap scalp electrode;103 is skull contact conductor port;104 is skull contact conductor;105 is spring;106 is electrode cap;107 skull electrode bed courses;108 is electrode cap scalp electrode bed course;109 electrode urceolus scalp electrode bed courses;110 is electrode urceolus;111 is electrode urceolus scalp electrode lead-in wire;112 is scalp electrode;113 is electrode cores;114 is electrode fixed mount;115 is electrode draw-in groove;116 is belt fixing device.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in further detail, and the explanation of the invention is not limited.
Referring to Fig. 1, the electrode assembly for zoopery impedance bioelectrical measurement scalp and skull disclosed by the invention, including electrode cap 106, electrode cores 113 and electrode urceolus 110;Electrode cores 113 is positioned at electrode urceolus 110, is connected with electrode urceolus 110 by screw thread, and electrode cores 113 adopts tapping screw thread, and conveniently adjusted electrode is positioned at the degree of depth of skull.Electrode cap 110 is set in above electrode urceolus 110.
Referring to Fig. 2-1 and 2-2, being provided with two contact conductor ports on electrode cap 106 top, centre is skull contact conductor port 103, and outside is scalp electrode lead-in wire port 101;Electrode cap 110 lower end is provided with skull electrode bed course 107, skull contact conductor port 103 is connected by skull contact conductor 104 with skull electrode bed course 107, it is provided with spring 105, to guarantee that skull electrode bed course 107 is connected with electrode cores 113 between electrode cap 106 top and skull electrode bed course 107.Electrode urceolus 110 top is provided with the screw thread adapted with electrode cap 106 inner surface.Being provided with electrode cap scalp electrode bed course 108 in electrode cap 106 lower end, scalp electrode lead-in wire port 101 is connected by electrode cap scalp electrode lead-in wire 102 with electrode cap scalp electrode bed course 108.
Referring to Fig. 3-1,3-2,4-1 and 4-2, being provided with electrode urceolus scalp electrode bed course 109 in electrode urceolus 110 upper end, lower end is provided with scalp electrode 112, and scalp electrode 112 is connected with electrode urceolus scalp electrode bed course 109 by electrode urceolus scalp electrode lead-in wire 111.
When electrode urceolus 110 is connected with electrode cap 106, electrode urceolus scalp electrode bed course 109 and electrode cap scalp electrode bed course 108 are in close contact.
Referring to Fig. 5-1 and 5-2, outside this electrode assembly, it is additionally provided with electrode fixed mount 114, and is formed around electrode draw-in groove 115 at electrode fixed mount 114, electrode fixed mount 114 is additionally provided with belt fixing device 116.
Further, described electrode cap 106, electrode urceolus 110 and electrode fixed mount 114 are by polymethyl methacrylate, and abbreviation code name is PMMA, is commonly called as lucite and makes;Described skull electrode bed course 107 and electrode cores 113 are made by the good conductor that copper or silver etc. are electric;Described belt fixing device 116 is made for rubber.
The electrode assembly for zoopery impedance bioelectrical measurement scalp and skull of the present invention, in use:
First, electrode is fixed in the draw-in groove 115 on electrode fixed mount 114, then, on the downside of belt fixing device 116 traverse brain, and regulates belt fixing device 116 length, make electrode assembly of the present invention and brain close contact.
After installing, can be used for scalp electrode and the impedance bioelectrical measurement of skull electrode both of which:
1) scalp electrode measurement pattern: first, appropriate conductive paste is smeared to scalp electrode, then electrode fixed mount 114 fixed electrode is utilized, finally, regulate the height of electrode cores 113, making electrode cores 113 lower end be positioned at electrode urceolus 110, namely the lower end of electrode cores 113 is higher than scalp electrode 112, and scalp electrode 112 can be fully contacted with scalp.
2) skull electrode mode measurement: regulating the height of electrode cores 113, make electrode cores 113 lower end be positioned at outside electrode urceolus 110, namely the lower end of electrode cores 113 is lower than scalp electrode 112, and rotatable electrode core 113 regulates the electrode degree of depth in skull.
After electrode is fixed and adjusted, according to drainage pattern, by skull contact conductor 104, electrode cap scalp electrode lead-in wire 102 and electrode urceolus scalp electrode lead-in wire 111 connection impedance bioelectrical measurement system, carry out impedance bioelectrical measurement.
In sum, a kind of scalp for impedance bioelectrical measurement provided by the invention and skull multipurpose electrode, it is achieved that carry out the zooperal multipurpose electrode of impedance bioelectrical measurement technology, including scalp electrode and skull electrode.
Electrode assembly for zoopery impedance bioelectrical measurement scalp and skull provided by the invention, electrode cap top is provided with two contact conductor outlets, centre is skull contact conductor, outside goes between for scalp electrode, skull contact conductor is connected with the skull electrode bed course of electrode cap lower end, scalp electrode lead-in wire is connected with scalp electrode bed course, has spring, to guarantee that skull electrode bed course is connected with electrode cores between skull electrode bed course and electrode cap.Electrode urceolus is connected by screw thread with electrode cap, there is scalp electrode bed course in the outside of electrode urceolus, when electrode container is connected with electrode cap, the scalp electrode bed course of electrode urceolus can be in close contact with electrode cap lower end electrode bed course, electrode urceolus lower end is scalp electrode, and is connected with upper end scalp electronic pads layer.Electrode cores is positioned at electrode urceolus, the height of scalable electrode cores.When needs carry out scalp electrode measure time, the height of adjustment so that it is lower end is positioned at electrode outer barrel, to ensure contacting of scalp electrode and scalp;When needs carry out craniometry, regulate the height of electrode cores, to change electrode cores degree of depth in skull.Electrode is fixed by electrode fixed mount.The scalp for impedance bioelectrical measurement of this invention offer and skull multipurpose electrode, achieve in the scalp of zoopery deutocerebral region impedance bioelectrical measurement and the many measurement patterns of skull, measurement pattern accurately can be controlled, it is particularly well-suited to zoopery deutocerebral region impedance bioelectrical measurement, it is simple to operation and accurately measurement.Employing discrete designs, it is simple to the cleaning of device, thus ensure that the accuracy of measurement, adopts helicitic texture, spring, it is ensured that scalp electrode circuit and the combining closely of each element in skull telegraph circuit.This device is easy to use, simple to operate, provides reliable guarantee for carrying out zoopery smoothly.

Claims (10)

1. the electrode assembly for zoopery impedance bioelectrical measurement scalp and skull, it is characterised in that include electrode cap (106), electrode cores (113) and electrode urceolus (110);Electrode cores (113) is arranged in electrode urceolus (110), and electrode cap (110) is set in electrode urceolus (110) top;
Be provided with two contact conductor ports on electrode cap (106) top, centre is skull contact conductor port (103), and outside is scalp electrode lead-in wire port (101);Electrode cap (110) lower end is provided with skull electrode bed course (107), skull contact conductor port (103) is connected by skull contact conductor (104) with skull electrode bed course (107), is provided with spring (105) between electrode cap (106) top and skull electrode bed course (107);Being provided with electrode cap scalp electrode bed course (108) in electrode cap (106) lower end, scalp electrode lead-in wire port (101) is connected by electrode cap scalp electrode lead-in wire (102) with electrode cap scalp electrode bed course (108);It is provided with electrode urceolus scalp electrode bed course (109) in electrode urceolus (110) upper end, lower end is provided with scalp electrode (112), and scalp electrode (112) is connected with electrode urceolus scalp electrode bed course (109) by electrode urceolus scalp electrode lead-in wire (111);
When electrode urceolus (110) is connected with electrode cap (106), electrode urceolus scalp electrode bed course (109) is in close contact with electrode cap scalp electrode bed course (108).
2. the electrode assembly for zoopery impedance bioelectrical measurement scalp and skull according to claim 1, it is characterised in that electrode urceolus (110) top is provided with the screw thread adapted with electrode cap (106) inner surface.
3. the electrode assembly for zoopery impedance bioelectrical measurement scalp and skull according to claim 1, it is characterised in that electrode cores (113) is threadingly attached in electrode urceolus (106).
4. the electrode assembly for zoopery impedance bioelectrical measurement scalp and skull according to claim 1, it is characterized in that, outside this electrode assembly, it is additionally provided with electrode fixed mount (114), and is formed around electrode draw-in groove (115) at electrode fixed mount (114).
5. the electrode assembly for zoopery impedance bioelectrical measurement scalp and skull according to claim 4, it is characterised in that be additionally provided with belt fixing device (116) on electrode fixed mount (114).
6. the electrode assembly for zoopery impedance bioelectrical measurement scalp and skull according to claim 1, it is characterized in that, skull contact conductor (104), electrode cap scalp electrode lead-in wire (102) are all connected with impedance bioelectrical measurement device with electrode urceolus scalp electrode lead-in wire (111).
7. the electrode assembly for zoopery impedance bioelectrical measurement scalp and skull according to claim 1, it is characterised in that electrode cap (106) and electrode urceolus (110) are made by lucite.
8. the electrode assembly for zoopery impedance bioelectrical measurement scalp and skull according to claim 1, it is characterised in that skull electrode bed course (107) and electrode cores (113) are made by electric good conductor.
9. the electrode assembly for zoopery impedance bioelectrical measurement scalp and skull according to claim 1, it is characterized in that, during scalp electrode measurement pattern, electrode cores (113) lower end is positioned at electrode urceolus (110), and scalp electrode (112) and scalp are fully contacted.
10. the electrode assembly for zoopery impedance bioelectrical measurement scalp and skull according to claim 1, it is characterized in that, during skull electrode mode measurement, electrode cores (113) lower end is positioned at electrode urceolus (110) outward, regulates the electrode degree of depth in skull by electric rotating pole piece (113).
CN201610108656.4A 2016-02-26 2016-02-26 Electrode device for measuring scalp and skull impedance in animal experiments Active CN105769193B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
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CN110292382A (en) * 2019-05-31 2019-10-01 海口市人民医院 A kind of brain injury animal model building composition monitoring device
CN113101517A (en) * 2021-04-15 2021-07-13 中国医学科学院北京协和医院 Implantable electrode device and preparation method thereof

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CN103830841A (en) * 2012-11-26 2014-06-04 塞恩克公司 Wearable transdermal electrical stimulation devices and methods of using them
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110292382A (en) * 2019-05-31 2019-10-01 海口市人民医院 A kind of brain injury animal model building composition monitoring device
CN113101517A (en) * 2021-04-15 2021-07-13 中国医学科学院北京协和医院 Implantable electrode device and preparation method thereof
CN113101517B (en) * 2021-04-15 2022-02-01 中国医学科学院北京协和医院 Implantable electrode device and preparation method thereof

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