CN105769140B - A kind of multipoint mode radial artery pulse condition collecting system and method - Google Patents
A kind of multipoint mode radial artery pulse condition collecting system and method Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7225—Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
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Abstract
The invention discloses a kind of multipoint mode radial artery pulse condition collecting system and methods, including iconography sensor, pressure sensor, optical fibre displacement sensor and electrocardio electropulsograph, iconography sensor is connected to host by image pick-up card, pressure sensor, optical fibre displacement sensor and electrocardio electropulsograph pass through signal conditioning circuit, including amplification, filter circuit, it is connected to cpu controller, data collecting card and A/D converter, after security isolation circuit (DC DC), is connected to host.Pressure probe provided by the invention, elastic element system structure are simple, easy to implement.The response results of temperature and pressure are isolated by analytic method.
Description
Technical field
The invention belongs to technical field of medical equipment, are related to a kind of Chinese medicine pulse detecting device, and in particular to a kind of multiple spot
Formula radial artery pulse condition collecting system and method.
Background technology
Diagnosis by feeling the pulse is the important means that doctor obtains key diagnostic information using sense organ, the diagnosis and treatment experience of Chinese medicine and diagnosis
Theory primarily rests on the basis of observation and analysis, the conclusion of doctor's individual.The difference of sense organ sensibility and it is subjective because
The difference of element, has seriously affected the objectivity of diagnostic message.Modern age feel the pulse researcher using modern electronic technology, sensor technology
Various pulse diagnosis study work have been carried out with computer technology, pulse wave has been depicted, analyzes the substantially special of common Chinese medicine pulse
Sign, makes some progress so that the acquisition modes of data are more objective, but there is also certain problems, such as pressure
Data acquisition precision is not high, and data information and the TCM pulse diagnosis information of acquisition are not directly dependent upon, and data information cannot be carved comprehensively
Draw pulse condition information etc..
For the research that TCM pulse diagnosis objectifies, the present invention provides a kind of establish on the basis of Traditional Chinese Medicine diagnosis by feeling the pulse methodology
Chinese medicine pulse information acquisition system, more, more scientific, more intuitive information is extracted, and by information analysis and processing, in making
Doctor's diagnosis by feeling the pulse more objectifies, convenient for the succession of the foundation and experience of database.
Invention content
According to the above-mentioned deficiencies of the prior art, the technical problem to be solved by the present invention is to propose a kind of multipoint mode radial artery
Pulse condition collecting system and method acquire Chinese medicine pulse by merging multi-sensor technology, it is not comprehensive enough, several to solve data information
According to the not high problem of accuracy.
In order to solve the above-mentioned technical problem, the technical solution adopted by the present invention is：A kind of multipoint mode radial artery pulse-tracing collection
System, including iconography sensor, pressure sensor, optical fibre displacement sensor and electrocardio electropulsograph, iconography sensor pass through
Image pick-up card is connected to host, and pressure sensor, optical fibre displacement sensor and electrocardio electropulsograph pass through signal conditioning circuit, packet
Amplification, filter circuit are included, cpu controller, data collecting card and A/D converter are connected to, by security isolation circuit (DC-DC)
Afterwards, it is connected to host.The pressure sensor includes semiconductor detection unit, two times transfer unit and signal processing unit, and half
Conductor detection unit includes two semiconductor gauge Rε1And Rε2, semiconductor gauge Rε1And Rε2It is r to be located at radius0Circle
On diaphragm, circular film is located at the inside of pressure sensor, and pressure sensor is divided into two closed cavitys, is dry in cavity
Dry gas, two semiconductor gauges are defeated under pressure difference and Temperature Excitation effect by the pressure difference inside and outside diaphragm
Go out electrical response, electrical response signal is converted to pulse width signal by two times transfer unit, and signal processing unit passes through data decoupler
Isolate temperature and external and internal pressure difference and relative humidity.The semiconductor gauge Rε1It is arranged in center location, Rε2Setting exists
Diaphragm 0.89r0Circle on, the variable quantity of two resistance strain gages is identical, positive and negative opposite.The two times transfer unit includes two
Identical pulse signal conversion circuit, a semiconductor gauge are correspondingly connected with a pulse signal conversion circuit, pulse signal
Conversion circuit includes 555 timers, resistance R and capacitance C, resistance R be connected to 555 timers No. 2 pins and No. 3 pins it
Between, capacitance C is connected on No. 2 pins of 555 timers, No. 2 pins and No. 6 pin short circuits, No. 3 pins and No. 7 pin short circuits,
No. 7 pin output pulse width signals of 555 timers are to signal processing unit.The pulse width conversion of the pulse signal conversion circuit is public
Formula is τ=ln2CR, and τ is output pulse width in formula, and R is the electrical response value for the semiconductor gauge that circuit receives, and C is cloud
Female mark pseudo-capacitance, it is directly proportional to respective institute connecting resistance R that pulsewidth exports τ.The circular film is according in semiconductor detection unit
The strain variation of two semiconductor gauges is divided into normal strain section and negative strain section, with radius 0.63r0Concentric circles be
Boundary.
A kind of acquisition method of multipoint mode radial artery pulse condition collecting system, includes the following steps：S01, pressure sensor, light
Fine displacement sensor and electrocardio electropulsograph and iconography sensor acquire the various data informations of radial artery respectively, and iconography passes
Sensor sends the data to host by image pick-up card, other three kinds of sensors are by signal conditioning circuit the mould received
Quasi- voltage signal carries out a series of amplification, is filtered, and send outer A/D converter the analog signal that modulate circuit exports later
Carry out pattern conversion, computer is sent into after security isolation circuit；S02, by collected data information input database.Institute
State pressure sensor acquisition radial artery pressure the specific steps are：Step 1: pressure sensor is pressed on radial artery, semiconductor
The resistance of foil gauge is input to two times transfer unit and carries out pulse width conversion, output pulse width signal；Step 2: signal processing unit connects
The pulse width signal for receiving the output of two times transfer unit analyzes semiconductor strain using Dalton's law, foil gauge principle and analytic method
The variable quantity of piece parses the pressure information acted on radial artery；Step 3: being held to the pressure acted on radial artery
Continuous analysis, because radial artery pulse can cause a pressure increment, by relatively subtracting each other to multiple numerical value, you can to extract oar
The pulsating force of artery.
Present invention has the advantages that:Present invention has the advantages that:1. pressure probe 6 provided by the invention, elastic element system
It unites simple in structure, easy to implement.
2. being obtained through analytic method：By the excitation of temperature and pressure difference, the response results of temperature and pressure are isolated.
Description of the drawings
The content expressed by this specification attached drawing and the label in figure are briefly described below：
Fig. 1 be the present invention specific implementation mode sensor in foil gauge scheme of installation.
Fig. 2 is the structural schematic diagram of the sensor of the specific implementation mode of the present invention.
Fig. 3 is the diagram of strains of the foil gauge of the specific implementation mode of the present invention.
Fig. 4 is the sensor operating principles structure diagram of the specific implementation mode of the present invention.
Fig. 5 is the signal flow block diagram of the sensor of the specific implementation mode of the present invention.
Fig. 6 is the pulse width signal conversion circuit figure of the specific implementation mode of the present invention.
Fig. 7 is the system structure diagram of the specific implementation mode of the present invention.
Pressure 6 structure charts of probe of the specific implementation mode of Fig. 8 present invention
1 is U-shaped bearing in figure, and 2 be cavity, and 3 be diaphragm, and 4 be semiconductor gauge Rε1, 5 be semiconductor gauge Rε2, 6
For pressure probe 6.
Specific implementation mode
Below against attached drawing, by the description of the embodiment, each component that the specific implementation mode of the present invention is for example involved
Shape, construction, the mutual alignment and connection relation between each section, the effect of each section and operation principle, manufacturing process and
Operate with method etc., is described in further detail, to help those skilled in the art to inventive concept of the invention, technology
Scheme has more complete, accurate and deep understanding.
The Chinese medicine pulse acquisition system combination multi-sensor technology of the present invention, the Artery Vein movement letter at three positions of acquisition
Breath and pressure wave beating information, bore variation, change in displacement and the axle center of radial artery are intuitively reflected by pressure pulse wave information
Movement, and the dynamic 3 D image of blood flow beating is built, Chinese medicine pulse is reflected by the fundamental physical quantity of sensor acquisition
The essential characteristic of " position, number, shape, gesture ".
The pulse condition collecting system of the present invention includes iconography sensor, optical fibre displacement sensor, pressure sensor and electrocardio
Electropulsograph, iconography sensor can be continuously tracked the active procedure that arterial pulse was taken action at one in the period, pass through sectoring
Vertical covering of the fan two-dimensional ultrasound faultage image is obtained, cross section and the axis of arteries and veins position blood vessel can be taken by axially and transversely scanning
To activity, can it is intuitive, in real time, dynamic tracing vascular beat process, iconography sensor is connected to host by image pick-up card.
Pressure sensor, optical fibre displacement sensor and electrocardio electropulsograph pass through signal conditioning circuit, including amplification, filter circuit, connection
To cpu controller, data collecting card and A/D converter host is connected to after security isolation circuit (DC-DC).Host obtains
Take radial artery motion, vessel cross-sections variation real-time tracking image, radial artery pressure pulse wave, Artery Vein moving image,
Capacity of blood vessel and ECG signal.And by adjusting pulse pressure, imitate when Chinese medicine takes arteries and veins it is floating, in, heavy gimmick.
Iconography sensor obtains vertical covering of the fan two-dimensional ultrasound faultage image by sectoring, it is per second can continuous acquisition it is auspicious
Type ultrasonoscopy, real-time tracking vascular pulsatile status can obtain a series of consecutive images in a cardiac cycle, to intuitive
Observe the vascular beating rule of specific pulse condition in ground.Auspicious consecutive image is handled and measured, can get in a cardiac cycle
The characteristics of motion of a certain cross section of vascular of specific pulse condition.Image is carried out after centainly handling, it may be achieved specific pulse condition takes arteries and veins portion
The reproduction of position motion process.
It is proportionate between the area and pulse wave pressure of vascular, in a cardiac cycle, with cardiac ejection and relaxes
The cyclic activity opened, generating period changes therewith for form and the arteries and veins overpressure of vascular, and changing rule directly affects arteries and veins
As characteristic parameter.When pulse wave is by a certain blood vessel, wave can all occur for overpressure, blood flow and tube wall radial displacement
It is dynamic, wherein based on the radial displacement of ductus arteriosus wall.In the case where blood vessel distortion is less big, Intraarterial pressure becomes at any time
The waveform of change is similar to the waveform that vessel radius changes over time, and the present invention detects vessel radius at any time by pressure sensor
The waveform of variation obtains the waveform of intravascular pressure variation indirectly.
Specifically, the beating information of three position blood vessel of cun,guan,chi is measured using No. nine pressure sensors, every three biographies
Sensor measures a position, and for three sensors along blood vessel arranged radially, central sensor measures the power of simple vertical direction, and outer
Enclose the resultant force that sensor measures pulse pulsating force, skin tangential tension etc..Operation is carried out to two paths of signals, blood vessel diameter can be distinguished
To mechanical index such as pulsating force, axial tensile force blood vessel equivalent hardness.In three pressure sensors, the pressure of central sensor is most
It greatly, therefore, can be by the numerical response of three sensors, to realize that pulse positions.In the actual use process, first by
Medical staff substantially positions the position of pulse, and the pulse location of patient is substantially placed on to the underface of pressure probe 6, is then controlled
Pressure probe 6 moves downwardly to the position of skin surface 0.5-1.5cm, and medical staff is finely adjusted in the position to probe, by
There is little difference in the pressure sensor location of the difference of age, gender and individual, three position of cun,guan,chi, by medical staff to arteries and veins
Preliminary adjust is realized in the judgement of position of fighting.When pressure probe 6 is pressurizeed on the skin, pass through the value of feedback of sensor, three sensings
In device, the pressure value of central sensor should be maximum, then to realize the fine tuning of pressure probe 6.
Optical fibre displacement sensor by light projection by the tissue amount of being absorbed by the blood number, then optical signal is converted
For electric signal, the blood volume of pulse is shown with this, by pulse wave wave pattern analysis, can get heartbeat function, blood flow and
Abundant microcirculation physiological and pathological information.Electrocardio electropulsograph can be used as the time label of pulse wave, while reflect cardiac electrical cycle base
Eigen and state.It is analyzed in combination with electrocardiogram and sphygmogram, still to obtain the important parameters such as Pulse wave velocity,
To disclose contacting for the parameters such as clinical blood vessel elasticity, the resistance of blood flow being very concerned about and diagnosis by feeling the pulse.
Pulse signal can be converted to faint electric signal by pressure sensor, optical fibre displacement sensor and electrocardio electropulsograph,
Using signal conditioning circuit, the effect of signal conditioning circuit is that the analog voltage signal received is carried out a series of put
Greatly, the processing such as filtering.Outer A/D converter is sent to carry out pattern conversion the analog signal that modulate circuit exports later, by safety
Computer is sent into after isolation circuit.Since the signal of sensor output is generally between 0-5mV, subsequent processing cannot be done, because
This is preposition by amplifying circuit, and many Hz noises and low frequency component are mingled in the signal of amplifying circuit output, and the present invention uses
Eight rank voltage controlled voltage source high-pass filters eliminate these interference, filter out high-frequency noise and interference signal.
The present Chinese medicine pulse maximum defect of mode of feeling the pulse just is a lack of objective data, and the succession of experience is by very big
Limitation, and existing case cannot be recorded by an objective mode, as learning materials.Pulse condition of the present invention
The last one step of acquisition method is exactly the foundation of database, the data that above four sensors are acquired, patient information, with
And in the data inputs to database such as diagnostic result and the tracking of the subsequent state of an illness.
Pressure sensor provided by the invention isolates corresponding transition response using analytic method from a variety of motivators,
Pressure sensor is pressure probe 6 as shown in Figure 8, and pressure probe 6 is cylindrical-shaped structure, and pressure probe 6 is internally provided with
A piece of flexible sheet, it is two parts that flexible sheet, which pops one's head in pressure 6 points, forms the cavity of two sealings, is dry in cavity
Air, there are pressure differences for both sides.The side of pressure probe 6 is similar 1 structure of U-shaped bearing, between flexible sheet and U-shaped bearing 1
Form a dry air seal chamber.The one end of pressure probe 6 contacted with pulse is a hemispheric enclosed construction of class,
It is dry air seal chamber between diaphragm.Configuration two and half is led on the center of circle in diaphragm outer surface and the appropriate location by periphery
Body strain piece receives a variety of excitation informations from wrist with this device and is isolated after quadratic transformation and signal processing
The pressure information of beat pulse, there are draught head Δ P, above-mentioned circular film 3 to select brass diaphragm between two seal chambers.
Pressure sensor further includes semiconductor detection unit, two times transfer unit and signal processing unit, semiconductor detection
Semiconductor gauge R there are two being set in unitε1And Rε2It is r mounted on radius0Circular film on, semiconductor gauge is by piezoelectricity
The output resistance response that changes is hindered, electrical response signal is converted to pulse width signal, signal processing unit by two times transfer unit
Decoupling Analysis goes out the pressure information of two times transfer unit output.
In semiconductor detection unit, the resistance delta that two semiconductor gauges are generated by air pressure excitation is equal, positive negative
Instead, one of semiconductor gauge is mounted on center location, another semiconductor gauge is mounted on radius 0.89r0It is same
On the position of heart circle.Two times transfer unit includes two identical pulse signal conversion circuits, and a semiconductor gauge corresponds to
A pulse signal conversion circuit is connected, pulse signal conversion circuit includes 555 timers, resistance R and capacitance C, resistance R connections
Between No. 2 pins and No. 3 pins of 555 timers, capacitance C is connected on No. 2 pins of 555 timers, No. 2 pins and 6
Number pin short circuit, No. 3 pins and No. 7 pin short circuits, No. 7 pin output pulse widths of 555 timers are signally attached to signal processing
Unit.The pulse width conversion formula of pulse signal conversion circuit is τ=ln2CR, and τ is output pulse width in formula, and R is in circuit
Resistance, C are mica standard capacitance, and it is directly proportional to respective institute connecting resistance R that pulsewidth exports τ.Circular film detects single according to semiconductor
The strain variation of two semiconductor gauges in member is divided into normal strain section and negative strain section, with radius 0.63r0It is concentric
Circle is boundary.
Signal processing unit is converted into semiconductor gauge using the pressure difference between pressure probe 6 and U-shaped bearing 1
Output resistance, pulsewidth after quadratic transformation and its directly proportional to the difference of the counting of frequency always, it is poor suffered by foil gauge to calculate
Pressure value.Then the pressure between pressure probe 6 and skin is calculated according to differential pressure value.It is keeping between skin and pressure probe 6
In the case that pressure is constant, pulse is often beated once, all can be applied certain pressure to the air pressure in pressure probe 6, be led to
The pressure crossed between pressure skin and pressure probe 6 carries out sustainable analysis, so that it may be pressed with isolating the related of beat pulse
The data informations such as power.
The specific detection method of the pressure sensor of the present invention is as follows：Step 1: the peace of two semiconductor gauges of adjustment
Holding position keeps the resistance delta that two semiconductor gauges are generated by air pressure excitation equal, positive and negative opposite；Step 2: semiconductor
The resistance change of foil gauge is input to two times transfer unit and carries out pulse width conversion, output pulse width signal；Step 3: signal processing
Unit receives the pulse width signal of two times transfer unit output, is partly led using the analysis of Dalton's law, foil gauge principle and analytic method
Variable quantity, the diaphragm pressure at both sides difference data of body strain piece.
The signal processing unit is using the pressure difference between pressure probe 6 and U-shaped bearing 1, the arteries and veins after quadratic transformation
Wide and its directly proportional to the difference of the counting of frequency always, the logarithm of the sum of counting of environment temperature and sensitive resistance is inversely proportional pass
System calculates differential pressure value Δ P suffered by foil gauge, 6 pressure P of pressure probeMWith temperature value t.This is hereafter described in detail by the derivation of equation
The 6 pressure P of pressure sensor detection temperature t and pressure probe of inventionMDetailed process.
One, foil gauge and its transfer characteristic
In sensor foil gauge scheme of installation as shown in Figure 1, sensor structural schematic diagram as shown in Fig. 2, strain
The transfer characteristic and Strain Distribution of piece are as shown in Figure 3.Pressure probe 6 is cylindrical-shaped structure, and being internally provided with for pressure probe 6 is a piece of
Flexible sheet, 6 points by pressure probe of flexible sheet is two parts, forms the cavitys of two sealings, is the air of drying in cavity,
There are pressure differences for both sides, and the resistance variations by measuring semiconductor gauge calculate the pressure difference of diaphragm both sides.
The pressure P of pressure probe 6MStepless action is in the outer surface of flexible sheet, the then differential pressure of diaphragm both sides：
Δ P=PM–Pre(Pa) (1)
P in formulare=4104(Pa) it is the reference pressure set in seal chamber, under differential pressure Δ P effects, on membrane surface
The distribution of stress and strain is shown below：
Radial stress：
Radial strain：
In formula (2) and (3), it is membrane flexive modulus, about 7* that the present invention, which selects the preferable brass diaphragm of elasticity, E (Pa),
1010Pa, μ are Poisson's ratio, about 0.33, r0For the outer radius 40 (mm) of circular film 3, h is the diaphragm thickness of circular film 3
0.1 (mm), b are the thickness 5 (mm) of U-shaped bearing 1, and the height of U-shaped bearing 1 is 10 (mm), and Δ P is the difference for acting on diaphragm both sides
It presses (Pa), r (mm) is the radius of foil gauge position.
If known constant is substituted into (2) formula, circumferential stress σ can be obtainedR=0=8*104*ΔP(Pa) (4)。
The sensitivity coefficient K of foil gaugeεWith shown in transfer characteristic such as formula (5)：
R in formula0For t=0 DEG C and εrSheet resistance (Ω), K are strained when=0εAbout 125, Δ RεThen be foil gauge in εrExcitation
The variable quantity (Ω) of lower resistance can obtain (4) formula substitution (5)：
If by E=7*1010Pa substitutes into formula (6) it is found that the relative resistance change that foil gauge can be output, under maximum range
Also there was only 10-2Magnitude, therefore quadratic transformation and signal processing circuit need to be added in a device, to obtain required sensitivity and resolution
Power.
Two, quadratic transformation and signal transmit flow
Operation principle structure diagram as shown in figure 4, pressure sensor include semiconductor detection unit, two times transfer unit,
Signal processing unit is set in semiconductor detection unit there are two semiconductor gauge, and semiconductor gauge is become by piezoresistance
Change output resistance response, the output end of semiconductor detection unit connects two times transfer unit, and two times transfer unit receives semiconductor
Electrical response signal is converted to pulse width signal by the output signal of detection unit, two times transfer unit, two times transfer unit it is defeated
Outlet connection signal processing unit, the output signal of signal processing unit Decoupling Analysis two times transfer unit isolate pressure letter
Breath.
Signal flow block diagram is as shown in figure 5, two times transfer unit includes two identical pulse signal conversion circuits, pulse
Signaling conversion circuit is made of 555 timer C1 and C2, and two times transfer unit and signal processing unit are additionally provided with gating switch, choosing
It is switched with C3, signal processing unit is mainly organized as C4 microcontrollers.R in Fig. 5ε1And Rε2In PWUnder being encouraged with t, respectively generate different
R1And R2Response, they respectively generate τ after C1, C2 chip 555 of two identical pulse signal conversion circuits converts1With
τ2(S) pulsewidth exports, which send after C3 switching gates to C4 microcontrollers and carry out signal processing again.Pulse signal is converted
For circuit as shown in fig. 6, resistance R is connected between No. 2 pins of C timers 555 and No. 3 pins, capacitance C is connected to 555 timings
On No. 2 pins of device, No. 2 pins and No. 6 pin short circuits, No. 3 pins and No. 7 pin short circuits, No. 7 pins of 555 timers are defeated
Go out pulse width signal and is connected to signal processing unit.Due to the difference of foil gauge, resistance and output pulse width in two impulse circuits
R can be used1And R2、τ1And τ2It indicates.
Pulse width conversion formula：τ=ln2CR (S) corresponds to two pulse signal conversion circuits：
τ1=ln2C0·R1(S) (7)
τ2=ln2C0·R2(S) (8)
τ in formula1And τ2For the corresponding two-way pulsewidth output signal of two semiconductor gauges, R1And R2For semiconductor strain
The increased resistance value measurement unit of piece is Ω, C0(F) it is mica standard capacitance, about 0.72 × 10-6F, above formula show that pulsewidth is defeated
Go out and respective institute connecting resistance R1And R2It is directly proportional.
Three, in multifactor input, the decoupling processing of response is synthesized
In τ1And τ2In be implied with pressure probe 6 and skin between two kinds of information of pressure and temperature t, how to allow its
Subsequent Data processing separation need to realize information separation by data decoupler technology and restore.
R1And R2Resistance variations formula is：
R in formula0Resistance on the basis of=1000 Ω；B=4850 (K) is the resistance temperature coefficient of semiconductor gauge；T0=273 (K)
For reference temperature(TR)；T (K) is input temp；ΔRε1With Δ Rε2Respectively R1And R2Pressure swashs between skin and pressure probe 6
Encourage the lower resistance delta respectively generated.By above two formula it is found that as can allowing Δ Rε1With Δ Rε2Numerical value is identical, but positive and negative on the contrary, i.e.
(9) it is become with (10) formula：
Above two formula is subtracted each other or is added, so that it may isolate PMWith two kinds of input informations of t, that is, R1+R2=f when being addedt(T),
With R1-R2=f when subtracting each otherε(PW), i.e., and with the result of difference only corresponded with single input information, Δ Rε1=-Δ Rε2=Δ
Rε。
Referring to Fig. 2, entire diaphragm outer surface is under differential pressure Δ P effects, with radius r=0.63r0For boundary, divide into positive and negative
Two strain regions.By the center of circle part areas inner circle Wei Zheng ε, and the periphery excircle part then areas Wei Fu ε are leaned on, in the suitable of this two regions
On position, it can find that ε numerical value is equal but opposite polarity two points, one is in circle centre position, r1=0, and another point passes through (3) formula
It is calculated as r2=0.89r0Place.The identical semiconductor gauge of two piece performances is configured on this 2 points, and is allowed on its center and diaphragm
Reference point overlaps, and is then achieved that the quantitative relationship of formula (11) and (11).
Formula (11) plus formula (12) are obtained
ε information has been eliminated in above formula to (R1+R2) quantitative interference, however R1And R2It is respectively coupled to 555 chips
In charge-discharge circuit, therefore can not be by R1And R2It is directly added, need to just be realized at this time by data operation processing.If allowing pulsewidth
τ1And τ2To clock frequency f in microcontroller0It counts, then has count value N1And N2For：
N1=τ1·f0 (14)
N2=τ2·f0 (15)
τ1+τ2=(N1+N2)/f0(S) (16)
Simultaneous above formula, and can be obtained by arrangement：
Celsius temperature：T=T-273 (DEG C) (18)
Each constant coefficient is in R in formula0=1000 Ω, C0=7.2*10-6F and f0It is calculated under the conditions of=10MHZ.From R1With
R2Two times transfer information in isolate strain and pressure probe 6 pressure PMEtc. information, (11) formula is subtracted into (12) formula, can be obtained
R1-R2=2 Δs Rε=2R0Kε·ε(Ω) (19)
Recycle τ1-τ2=(N1-N2)/f0(3), the simultaneous such as (7), (8) formula, it is collated to obtain,
Δ P=10 (N1-N2)(Pa) (20)
Formula (17) and (20) are two kinds of input-output characteristic equations of pressure sensor, there is enough sensitivity
And resolving power.The pressure between skin and pressure probe 6 can be sought by formula (1), is kept between pressure probe 6 and skin
Contact dynamics it is constant, due to the bounce of interpulse interval, the pressure increment that beat pulse makes skin and pressure pop one's head between 6 encourages
The foil gauge on flexible sheet is set to generate corresponding response, the pressure differential Δ P of flexible sheet both sides increases, by popping one's head in pressure
6 pressure PMLasting observation, it is easy to obtain pressure probe PMIncrement information, the response knot of this namely beat pulse excitation
Fruit.
The present invention is exemplarily described above in conjunction with attached drawing, it is clear that the present invention implements not by aforesaid way
Limitation, as long as the improvement of the various unsubstantialities of inventive concept and technical scheme of the present invention progress is used, or without changing
Other occasions are directly applied to by the design of the present invention and technical solution, within protection scope of the present invention.This hair
Bright protection domain should be determined by the scope of protection defined in the claims.
Claims (5)
1. a kind of multipoint mode radial artery pulse condition collecting system, which is characterized in that including iconography sensor, pressure sensor, light
Fine displacement sensor, electrocardio electropulsograph and host, iconography sensor are connected to host, pressure sensing by image pick-up card
Device, optical fibre displacement sensor and electrocardio electropulsograph are connected to CPU controls by signal conditioning circuit, including amplification, filter circuit
Device, data collecting card and A/D converter are connected to host after security isolation circuit；
The pressure sensor includes semiconductor detection unit, two times transfer unit and signal processing unit, and semiconductor detection is single
Member includes two semiconductor gauge Rε1(4) and Rε2(5), semiconductor gauge Rε1(4) and Rε2(5) it is r to be located at radius0Circle
On shape diaphragm (3), circular film (3) is located at the inside of pressure sensor, and pressure sensor is divided into two closed cavitys, empty
Intracavitary is the gas of drying, and two semiconductor gauges are swashed by the pressure difference inside and outside diaphragm (3) in pressure difference and temperature
Electrical response signal is converted to pulse width signal by the lower output resistance response of the effect of encouraging, two times transfer unit, and signal processing unit is logical
Crossing data decoupler, to isolate external and internal pressure poor；
The semiconductor gauge Rε1(4) it is arranged in center location, Rε2(5) it is arranged in diaphragm (3) 0.89r0Circle on, partly lead
Body strain piece Rε1(4) and Rε2(5) the resistance delta numerical value respectively generated under air pressure excitation is equal, positive and negative on the contrary, r0For circle
The radius of diaphragm (3).
2. multipoint mode radial artery pulse condition collecting system according to claim 1, which is characterized in that the two times transfer unit
Including two identical pulse signal conversion circuits, a semiconductor gauge is correspondingly connected with a pulse signal conversion circuit,
Pulse signal conversion circuit include 555 timers, resistance R and capacitance C, resistance R be connected to 555 timers No. 2 pins and No. 3
Between pin, capacitance C is connected on No. 2 pins of 555 timers, No. 2 pins and No. 6 pin short circuits, and No. 3 pins and No. 7 are drawn
Foot short circuit, No. 7 pin output pulse width signals of 555 timers to signal processing unit.
3. multipoint mode radial artery pulse condition collecting system according to claim 2, which is characterized in that the pulse signal conversion
The pulse width conversion formula of circuit is τ=ln2CR, and τ is output pulse width in formula, and R is the semiconductor gauge that circuit receives
Electrical response value, C are mica standard capacitance, and it is directly proportional to respective institute connecting resistance R that pulsewidth exports τ.
4. multipoint mode radial artery pulse condition collecting system according to claim 1, which is characterized in that the circular film (3)
It is divided into normal strain section and negative strain section according to the strain variation of two semiconductor gauges in semiconductor detection unit, with
Radius 0.63r0Concentric circles be boundary.
5. the acquisition method of multipoint mode radial artery pulse condition collecting system according to any one of claims 1-4, feature
It is, includes the following steps：
S01, pressure sensor, optical fibre displacement sensor and electrocardio electropulsograph and iconography sensor acquire radial artery respectively
Various data informations, iconography sensor send the data to host by image pick-up card, other three kinds of sensors pass through letter
Number modulate circuit is amplified the analog voltage signal received, is filtered, and the simulation of modulate circuit output is believed later
It number gives A/D converter and carries out pattern conversion, computer is sent into after security isolation circuit；
S02, by collected data information input database；
Pressure sensor acquisition radial artery pressure the specific steps are：
Step 1: pressure sensor is pressed on radial artery, the resistance of semiconductor gauge is input to the progress of two times transfer unit
Pulse width conversion, output pulse width signal；
Step 2: signal processing unit receives the pulse width signal of two times transfer unit output, it is former using Dalton's law, foil gauge
The variable quantity of reason and analytic method analysis semiconductor gauge, parses the pressure information acted on radial artery；
Step 3: carrying out continual analysis to acting on the pressure on radial artery, radial artery pulse can cause a pressure increment, lead to
It crosses and multiple numerical value is relatively subtracted each other, extract the pulsating force of radial artery.
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| CN100346740C (en) * | 2003-05-20 | 2007-11-07 | 香港中文大学 | Blood pressure measuring device and method based on the pulse information of radial artery |
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