CN105748297A - Sugar tolerance test method - Google Patents

Abstract

The invention provides a sugar tolerance test method.The sugar tolerance test method comprises the steps that a sugar tolerance test is performed by utilizing an oral glucose tolerance test device; a tested person is phlebotomized at empty stomach at 7:00 in the morning after 10 hours of nesteia for blood sugar testing; a bottle cap of the oral glucose tolerance test device is opened, and the amount of poured boiled water is controlled by utilizing a quantifying unit; the bottle cap is tightened, up-down, front-back or left-right even shaking is performed for dissolving drugs for the test, and a solution with uniform concentration is obtained; the solution is drunken within 5 minutes, and a reminding unit is started at the first swallow of the solution; phlebotomizing is performed at 30 minutes, 60 minutes, 120 minutes and 180 minutes respectively after timing by utilizing the reminding unit for blood sugar testing; result reading is performed.By the adoption of the method, convenience can be brought to a patient, it can be also guaranteed that the solution concentration is uniform in the testing process, the volume and temperature of the solution can be accurately, conveniently and timely measured, the oral glucose tolerance test device is very quick and convenient to use and has the functions of health education and timed reminding, the compliance of the patient is high, and the efficiency and accuracy of the glucose tolerance test are greatly improved.

Description

Carbohydrate tolerance test method

Technical field

The invention belongs to field of medicaments, concrete, relate to a kind of carbohydrate tolerance test method.

Background technology

Oral glucose tolerance test (Oralglucosetolerance, OGTT) diabetes suspected patient it is used for, when blood glucose increases but not yet reaches diabetes diagnostic criterion, whether suffer from diabetes for clear and definite, it is possible to adopt OGTT test to carry out differentiating to judge.After normal person takes a certain amount of glucose, blood glucose first raises, but after certain time, glucose glycogen biosynthesis is stored by human body, and namely blood glucose return to fasting level.After taking a certain amount of glucose, separated in time measures blood glucose and glucose in urine, observes to the change of blood sugar concentration before and after sugar, and so as to knowing insulin secretion situation by inference, this mensuration is called carbohydrate tolerance test.

The examination mode that hospital is traditional, it is when on an empty stomach, after the glucose sack filling 75g glucose powder (25g/ bag * 3 wraps) is torn, it is put in disposable water cup and dissolves, after taking, separated in time measures blood glucose and glucose in urine, by observing to the change of blood sugar concentration before and after sugar, so as to knowing insulin secretion situation by inference.In view of the personnel's most advanced age participating in test, patient compliance is poor, and the method operation is inconvenient for, artificial controlled standard differs, and 3 bag Icing Sugar need to tear successively, and water tumbler capacity not can determine that and inconvenience stirring, individual variation is stronger, instructions of taking not can determine that, interval time can not accurately be affirmed, result interpretation method can not intuitively be determined.Thereby result in measurement result and there is relatively large deviation, and then the later stage is diagnosed and treated generation harmful effect.

Therefore, carbohydrate tolerance test method is still further improved.

Summary of the invention

It is contemplated that solve one of technical problem of existing in prior art at least to a certain extent or provide at a kind of useful business and select.For this, it is an object of the present invention to provide a kind of carbohydrate tolerance test method, utilize the method, both can be easy to patient and carry, can ensure again in process of the test, solution concentration is homogeneous, and its volume, temperature can accurately, convenient, measure timely, it is very convenient to use, and has health education function and timing reminding function, patient compliance is high, substantially increases efficiency and the accuracy of carbohydrate tolerance test.

For this, in one aspect of the invention, it is proposed that a kind of carbohydrate tolerance test method.According to one embodiment of present invention, oral glucose tolerance test device is utilized to carry out carbohydrate tolerance test, wherein,

Described oral glucose tolerance test device includes:

Bottle, described bottle has the first opening and bottom, is contained with test medicine in bottle, and described bottle arranged outside has dosing unit；

Bottle cap, dismountable and described bottle the first opening of described bottle cap is connected；

Health education unit, it is peripheral that described health education unit is arranged on described bottle；

Reminding unit, described reminding unit is dismountable and described bottle cap is connected；

Described glucose tolerance test method includes:

(1), during morning 7 after fasting 10 hours, phlebotomize sugar of having a blood test on an empty stomach；

(2) open described bottle cap, utilize dosing unit to control to pour into the amount of boiled water；

(3) tighten bottle cap, up and down, back and forth or left and right shake up, solubility test medicine, in order to the homogeneous solution of concentration；

(4) in 5 minutes, drink solution, and start described reminding unit when drinking first；

(5) 30 minutes, 60 minutes, 120 minutes and the 180 minutes sugar of having a blood test that phlebotomizes after timing；

(6) result interpretation.

Thus, the test method of the present invention, by using oral glucose tolerance test device, patient has only to screw bottle cap, up and down or front and back, or left and right shake a shaking flask body, both can ensure that in bottle, solution concentration is homogeneous, avoid liquid upper strata concentration in bottle low and the bottom concentration mouthfeel that causes of height is uncomfortable, and affect blood glucose response and differ；When can avoid again that in prior art, contingent water temperature is relatively low, do not add stirring and produce to remain undissolved Icing Sugar, thus the inaccurate phenomenon of measurement result occurred.Make liquor capacity accurate by dosing unit, it is ensured that measurement result is accurate；By health education, make patient compliance high, substantially increase the efficiency of carbohydrate tolerance test；Utilizing reminding unit, it is to avoid owing to interval is long, patient does not grasp the measurement time in time, incurs loss through delay blood sampling, and causes interpretation of result inaccurate, and by ensureing and supervising patient to judge the performance of blood examination number of times, blood sugar test is done in blood drawing on time.

According to embodiments of the invention, described test medicine is pure glucose, vitamin C, nicotiamide, vitamin B1, vitamin B2.

According to embodiments of the invention, the specification of described test medicine is 75 grams.The medicine thus held in an oral glucose tolerance test device can meet a patient and carry out the consumption of an OGTT test, quantitatively accurate, easy to use.

According to embodiments of the invention, described reminding unit includes: intervalometer, and described intervalometer includes starting module and timing module；Device for digit-displaying, described device for digit-displaying is connected with described intervalometer；Signal lights, described signal lights is connected with described device for digit-displaying.Thus, after patient has drunk sucrose solution, start timing by starting module；By described timing module arranges the time point of 30 minutes, 60 minutes, 120 minutes and 180 minutes further, when reaching each time point, signal lights is bright, thus accurately reminds patient to do blood sugar test in time.Owing to reminding unit is to be pasted on bottle cap by dismountable mode, after a carbohydrate tolerance test makes to be finished device, reminding unit thereon can be disassembled, reclaim, calibration, recycle, can effectively reduce production cost.

According to embodiments of the invention, described startup module is Non-follow control button.Thus, it is simple to patient carries out real time operation.

According to embodiments of the invention, the built-in energy-saving electronic integrated chip of described timing module, the time point of 30 minutes, 60 minutes, 120 minutes and 180 minutes can be set.Described electronic chip battery is durable type battery, and recoverable.Described timing module receives the signal that described startup module gives and namely starts timing.

According to embodiments of the invention, described device for digit-displaying, when arriving each time point, shows the time of institute's timing.Thus, it is simple to patient judges the performance of blood examination number of times.

According to embodiments of the invention, described signal lights is LED.

According to embodiments of the invention, described dosing unit is segmentation volume markings.Thus, it is possible to grasp the change in volume of solution easily, and ensure that solution concentration meets requirements.By in the glucose stage of taking after mixing it with water, quantitatively hold add the water yield number, ensure that patient's dose is suitable, it is to avoid when syrup concentration is too high or too low, patient's palatability is poor.On the other hand, also it is unlikely to affect controlled micturition frequency, thus causing that urine examination result is inaccurate.

According to embodiments of the invention, the spacing value of described segmentation volume markings is 25ml, and minima is 0ml, and maximum is 350ml.According to a particular embodiment of the invention, it is poured in bottle by warm water 300ml scale place.Thus meet the syrup concentration demand of oral glucose tolerance test.

According to embodiments of the invention, described health education unit, with written form, describes test method and points for attention.Both indicate drinking method and screening results interpretation method, again patient is played directive function.Thus avoid hospital nursing staffs before on-test, it is necessary to every patient is repeatedly performed oral health education.Also avoiding because of the impact of the factor such as patient age, memory or faculty of understanding, patient is that may be present to incur loss through delay in blood sampling or blood collection procedure feed again etc. and causes test to interrupt or the inaccurate situation of testing result occurs.

According to embodiments of the invention, described health education unit is further provided with data storage area.Thus it is easy to the information of every patient's instant recording oneself, it is to avoid obscure and lose.

According to embodiments of the invention, what described data storage area included experimenter's information and different periods testing result record writes region.Described experimenter's information includes patient's name etc..Described different periods testing result record includes detection time, blood glucose value etc..

According to embodiments of the invention, outside described bottle, movably it is provided with temperature measuring apparatus.According to a particular embodiment of the invention, described temperature measuring apparatus is thermometer.Described thermometer can be bundled in the first opening of bottle with lower portion by stretch cord.Thereby it is ensured that temperature can accurately, convenient, measure timely.In specific embodiments of the invention, it is poured in cup by the warm water of 50 degrees centigrade 300ml scale place.

According to embodiments of the invention, described bottle is translucent glass body or plastic bottle body.Thus, it is simple to the dissolving of content and drink situation in immediate observation bottle.

The additional aspect of the present invention and advantage will part provide in the following description, and part will become apparent from the description below, or is recognized by the practice of the present invention.

Accompanying drawing explanation

Fig. 1 is the structural representation of oral glucose tolerance test device according to an embodiment of the invention；

Fig. 2 is the method flow schematic diagram utilizing oral glucose tolerance test device to carry out carbohydrate tolerance test according to an embodiment of the invention.

Detailed description of the invention

Being described below in detail embodiments of the invention, the example of described embodiment is shown in the drawings, and wherein same or similar label represents same or similar element or has the element of same or like function from start to finish.The embodiment described below with reference to accompanying drawing is illustrative of, it is intended to is used for explaining the present invention, and is not considered as limiting the invention.

In one of invention, the present invention proposes a kind of a kind of method utilizing oral glucose tolerance test device to carry out carbohydrate tolerance test.

With reference to Fig. 1, the oral glucose tolerance test device of the present invention includes:

According to embodiments of the invention, a kind of oral glucose tolerance test device 1000 specifically includes that bottle 100, bottle cap 200, health education unit 300, reminding unit 400.

According to one embodiment of present invention, bottle 100 has the first opening 110 and bottom 120, is contained with test medicine in bottle 100, and bottle 100 arranged outside has dosing unit 130；Bottle cap 200 is removably connected with the first opening 110 of bottle 100；It is peripheral that health education unit 300 is arranged on bottle 100；Reminding unit 400 is dismountable to be connected with bottle cap 200.

With reference to Fig. 2, the present invention carries out the method for carbohydrate tolerance test and includes:

S100: during morning 7 after fasting 10 hours, phlebotomize sugar of having a blood test on an empty stomach；

S200: open described bottle cap, utilizes dosing unit to control to pour into the amount of boiled water；

S300: tighten bottle cap, up and down, back and forth or left and right shake up, solubility test medicine, in order to the homogeneous solution of concentration；

S400: drunk solution in 5 minutes, and started described reminding unit when drinking first；

S500: 30 minutes, 60 minutes, 120 minutes and the 180 minutes sugar of having a blood test that phlebotomizes after timing；

S600: result interpretation.

Thus, the test method of the present invention, by using oral glucose tolerance test device, without still further arranging agitating device, patient has only to screw bottle cap 200, upper and lower or front and back, or left and right shake a shaking flask body, both can ensure that in bottle, solution concentration was homogeneous, it is to avoid in bottle, liquid upper strata concentration is low and mouthfeel that bottom concentration height causes is uncomfortable, and affect blood glucose response and differ；When can avoid again that in prior art, contingent water temperature is relatively low, do not add stirring and produce to remain undissolved Icing Sugar, thus the inaccurate phenomenon of measurement result occurred.Make liquor capacity accurate by dosing unit, it is ensured that measurement result is accurate；By health education, make patient compliance high, substantially increase the efficiency of carbohydrate tolerance test；Utilizing reminding unit, it is to avoid owing to interval is long, patient does not grasp the measurement time in time, incurs loss through delay blood sampling, and causes interpretation of result inaccurate, and by ensureing and supervising patient to judge the performance of blood examination number of times, blood sugar test is done in blood drawing on time.

An embodiment according to invention, bottle 100 and bottle cap 200 pass through screw thread 140 be connected (in accompanying drawing 2 with the bottle cap 200 corresponding to bottle 100 screw thread inside screw thread not shown).Thereby it is ensured that when patient carries out shake bottle 100, solution will not be revealed from the first opening 110.

According to embodiments of the invention, it is provided with hard type striped on around bottle cap 200 is longitudinal, reduces the problem that hands is sliding by increasing frictional force.

According to embodiments of the invention, reminding unit 400 includes: intervalometer 410, device for digit-displaying 420 and signal lights 430.Intervalometer 410 includes starting module 411 and timing module 412；Device for digit-displaying 420 is connected with intervalometer 410；Signal lights 430 is connected with device for digit-displaying 420.Thus, after patient has drunk sucrose solution, start timing by starting module 411.

According to a particular embodiment of the invention, timing module 412 is further arranged to the time point of 30 minutes, 60 minutes, 120 minutes and 180 minutes, and when reaching each time point, signal lights 430 is bright, thus accurately reminds patient to do blood sugar test in time.

According to a particular embodiment of the invention, starting module 411 is Non-follow control button.Thus, it is simple to patient carries out real time operation.

According to a particular embodiment of the invention, the built-in energy-saving electronic integrated chip of timing module 412, the time point of 30 minutes, 60 minutes, 120 minutes and 180 minutes can be set.Described electronic chip battery is durable type battery, and recoverable.Timing module 412 receives and starts the signal that gives of module 411 and namely start timing.

According to a particular embodiment of the invention, device for digit-displaying 420, when arriving each time point, shows the time of institute's timing.Thus, it is simple to patient judges the performance of blood examination number of times.

According to a particular embodiment of the invention, signal lights 430 is LED.

According to inventive embodiment, dosing unit 130 is the segmentation volume markings of distribution outside bottle 100.Thus, it is possible to grasp the change in volume of solution easily, and ensure that solution concentration meets requirements.By in the glucose stage of taking after mixing it with water, quantitatively hold add the water yield number, thereby guarantee that patient's dose is suitable, it is to avoid when syrup concentration is too high or too low, patient's palatability is poor.On the other hand, also it is unlikely to affect controlled micturition frequency, thus causing that urine examination result is inaccurate.

According to embodiments of the invention, the spacing value of segmentation volume markings is 25ml, and maximum is 350ml.According to a particular embodiment of the invention, it is poured in cup by warm water 300ml scale place.

According to embodiments of the invention, health education unit 300, with written form, describes test method and points for attention, has both indicated drinking method and screening results interpretation method, again patient has been played directive function.Thus avoid hospital nursing staffs before on-test, it is necessary to the problem that every patient is repeatedly performed oral health education；Also avoiding because of the impact of the factor such as patient age, memory or faculty of understanding, patient is that may be present to incur loss through delay in blood sampling or blood collection procedure feed again etc. and causes test to interrupt or the inaccurate situation of testing result occurs.

According to a particular embodiment of the invention, the word content of health education unit 300 mark is as follows:

Oral glucose tolerance test OGTTCup

Eating method:

1, during morning 7 after fasting 10 hours, phlebotomize sugar of having a blood test on an empty stomach；

2, open bottle cap, be poured in cup by about 50 DEG C warm waters 300mL scale place；

3, tighten bottle cap, shake up sucrose solution；

4, in 5 minutes, drink sucrose solution, and start timing when drinking first；

5, respectively at clothes sugar half an hour after, 1 hour, 2 hours and the 3 hours sugar of having a blood test that phlebotomizes；

6, result interpretation.

OGTT is a kind of glucosieloading test, it is therefore an objective to by measuring islet cell function, confirm diabetes, is only applicable to blood glucose higher than normal value and not up to the crowd diagnosing diabetes standard.

Normal person's blood glucose after saccharide of taking food can temporarily raise, summit it is raised to after 0.5-1 hour, but not can exceed that 8.9mmol/L, fasting level is returned to after 2 hours, diabetic and impaired glucose tolerance person then do not follow this rule, occur that blood glucose value raises and rhythm disturbance, owing to this test is belonging to oral glucose to increase blood sugar level value, be unfit to do this test when patient is diagnosed as diabetes.

OGTT result interpretation:

1, when vein fasting glucose, < < 7.8mmol/L illustrates that human body is normal to the blood sugar regulation ability after glucose load, for normal glucose tolerance to 6.1mmol/L, OGTT two hours blood glucose.

2, as vein fasting glucose >=7.0mmol/L or OGTT two hours blood glucoses >=11.1mmol/L, glucose in urine+～++++, illustrate that the ability of human body process post-prandial glucose substantially reduces, reached the diagnostic criteria of diabetes.

3, when vein fasting glucose, < 7.0mmol/L and OGTT two hours blood glucose, between 7.8～11.1mmol/L, illustrates that the regulating power of glucose is slightly declined by human body, has reached the diagnostic criteria of impaired glucose tolerance.

4, when vein fasting glucose is between 6.1～7.0mmol/L, and OGTT two hours blood glucoses≤7.8mmol/L, illustrate that human body is fair to the blood sugar regulation ability after glucose load, but fasting glucose regulating power is slightly gone down, reached the diagnostic criteria of impaired fasting glucose (IFG).

According to embodiments of the invention, health education unit 300 is further provided with data storage area 310.Thus it is easy to the information of every patient's instant recording oneself, it is to avoid obscure and lose.

According to embodiments of the invention, what data storage area 310 included experimenter's information and different periods testing result record writes region.Described experimenter's information includes patient's name etc..Described different periods testing result record includes detection time, blood glucose value etc..

According to embodiments of the invention, outside bottle 100, movably it is provided with temperature measuring apparatus 150.According to a particular embodiment of the invention, temperature measuring apparatus 150 is common thermometer, is bundled in the first opening 110 of bottle 100 with lower portion by stretch cord 160.Thereby it is ensured that temperature can accurately, convenient, measure timely.In specific embodiments of the invention, it is poured in cup by the warm water of 50 degrees centigrade 300ml scale place.

According to embodiments of the invention, bottle 100 is translucent glass body or plastic bottle body.Thus, it is simple in immediate observation bottle, glucose dissolves and drinks situation.

In describing the invention, it will be appreciated that, term " " center ", " longitudinal direction ", " transverse direction ", " length ", " width ", " thickness ", " on ", D score, " front ", " afterwards ", " left side ", " right side ", " vertically ", " level ", " top ", " end " " interior ", " outward ", " clockwise ", " counterclockwise ", " axially ", " radially ", orientation or the position relationship of the instruction such as " circumference " are based on orientation shown in the drawings or position relationship, it is for only for ease of the description present invention and simplifies description, rather than the device of instruction or hint indication or element must have specific orientation, with specific azimuth configuration and operation, therefore it is not considered as limiting the invention.

Additionally, term " first ", " second " are only for descriptive purposes, and it is not intended that indicate or imply relative importance or the implicit quantity indicating indicated technical characteristic.Thus, define " first ", the feature of " second " can express or implicitly include one or more these features.In describing the invention, " multiple " are meant that two or more, unless otherwise expressly limited specifically.

In the present invention, unless otherwise clearly defined and limited, the term such as term " installation ", " being connected ", " connection ", " fixing " should be interpreted broadly, for instance, it is possible to it is fixing connection, it is also possible to be removably connect, or integral；Can be mechanically connected, it is also possible to be electrical connection；Can be joined directly together, it is also possible to be indirectly connected to by intermediary, it is possible to be connection or the interaction relationship of two elements of two element internals.For the ordinary skill in the art, it is possible to understand above-mentioned term concrete meaning in the present invention as the case may be.

In the present invention, unless otherwise clearly defined and limited, fisrt feature second feature " on " or D score can be that the first and second features directly contact, or the first and second features are by intermediary mediate contact.And, fisrt feature second feature " on ", " top " and " above " but fisrt feature directly over second feature or oblique upper, or be merely representative of fisrt feature level height higher than second feature.Fisrt feature second feature " under ", " lower section " and " below " can be fisrt feature immediately below second feature or obliquely downward, or be merely representative of fisrt feature level height less than second feature.

In the description of this specification, specific features, structure, material or feature that the description of reference term " embodiment ", " some embodiments ", " example ", " concrete example " or " some examples " etc. means in conjunction with this embodiment or example describe are contained at least one embodiment or the example of the present invention.In this manual, what the schematic representation of above-mentioned term is not necessarily referring to is identical embodiment or example.And, the specific features of description, structure, material or feature can combine in one or more embodiments in office or example in an appropriate manner.Additionally, when not conflicting, the feature of the different embodiments described in this specification or example and different embodiment or example can be carried out combining and combining by those skilled in the art.

Although above it has been shown and described that embodiments of the invention, it is understandable that, above-described embodiment is illustrative of, it is impossible to be interpreted as limitation of the present invention, and above-described embodiment can be changed, revises, replace and modification by those of ordinary skill in the art within the scope of the invention.

Claims (10)

1. a carbohydrate tolerance test method, it is characterised in that utilize oral glucose tolerance test device to carry out carbohydrate tolerance test,

Wherein, described oral glucose tolerance test device includes:

Bottle, described bottle has the first opening and bottom, is contained with test medicine in bottle, and described bottle arranged outside has dosing unit；

Bottle cap, dismountable and described bottle the first opening of described bottle cap is connected；

Health education unit, it is peripheral that described health education unit is arranged on described bottle；

Reminding unit, described reminding unit is dismountable and described bottle cap is connected；

Described carbohydrate tolerance test method includes:

(1), during morning 7 after fasting 10 hours, phlebotomize sugar of having a blood test on an empty stomach；

(2) open described bottle cap, utilize dosing unit to control to pour into the amount of boiled water；

(3) tighten bottle cap, up and down, back and forth or left and right shake up, solubility test medicine, in order to the homogeneous solution of concentration；

(4) in 5 minutes, drink solution, and start described reminding unit when drinking first；

(5) 30 minutes, 60 minutes, 120 minutes and the 180 minutes sugar of having a blood test that phlebotomizes after timing；

(6) result interpretation.

2. method according to claim 1, it is characterised in that described test medicine is pure glucose, vitamin C, nicotiamide, vitamin B1, vitamin B2.

3. method according to claim 1, it is characterised in that the specification of described test medicine is 75 grams.

4. method according to claim 1, it is characterised in that described reminding unit includes:

Intervalometer, described intervalometer includes starting module and timing module；

Device for digit-displaying, described device for digit-displaying is connected with described intervalometer；

Signal lights, described signal lights is connected with described device for digit-displaying.

5. method according to claim 1, it is characterised in that described dosing unit is segmentation volume markings；

Optionally, the spacing value of described segmentation volume markings is 25 milliliters；

Optionally, the minima of described segmentation volume markings is 0 milliliter, and maximum is 350 milliliters.

6. method according to claim 1, it is characterised in that described health education unit, with written form, describes test method and points for attention.

7. method according to claim 1, it is characterised in that described health education unit is further provided with data storage area.

8. method according to claim 1, it is characterised in that what described data storage area included experimenter's information and different periods testing result record writes region.

9. method according to claim 1, it is characterised in that be movably provided with temperature measuring apparatus outside described bottle.

10. method according to claim 1, it is characterised in that described bottle is translucent glass body or plastic bottle body.