CN105738247B - A kind of the air pressure detection method and its dedicated test cup of thrombelastogram - Google Patents
A kind of the air pressure detection method and its dedicated test cup of thrombelastogram Download PDFInfo
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- CN105738247B CN105738247B CN201610106327.6A CN201610106327A CN105738247B CN 105738247 B CN105738247 B CN 105738247B CN 201610106327 A CN201610106327 A CN 201610106327A CN 105738247 B CN105738247 B CN 105738247B
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- cup
- thrombelastogram
- air
- detection method
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N7/00—Analysing materials by measuring the pressure or volume of a gas or vapour
Abstract
A kind of air pressure detection method of thrombelastogram, which is characterized in that described detection method includes the following steps: blood sample merging to be detected is divided into the two-part detection cup in left and right by Step 1. with isolation bar, then will test cup sealing by two butyl rubber plugs；Step 2. is inserted into butyl rubber plug using two hollow needles respectively, so that the air of this side is in sealing state by closing solenoid valve the hollow needle on right side；Step 3. regularly adjusts right side by operating precise micro air pump, while gas micro-pressure sensor uninterrupted recording surveys the gas pressure value in 1 inner sealing space of cup；Step 4. is by micro-pressure sensor as blood sample solidifies the tonogram that all data being recorded during retrogradation depict entire coagulation process, i.e. thrombelastogram.The air pressure detection method dedicated test cup of a kind of thrombelastogram, it is characterised in that: isolation bar is equipped among the detection cup, from detection cup bottom of a cup 3-5mm, the detection cup upper end sets that there are two butyl rubber plugs for the isolation bar bottom.
Description
Technical field
The present invention relates to medical science, the air pressure detection method and its dedicated test of espespecially a kind of thrombelastogram
Cup.
Background technique
Blood coagulation, i.e. blood clotting refer to the process of that blood becomes not flowable gel state by the liquid condition flowed,
It is the important link of physiological haemostasis.Hemostasis examination content is blood coagulation four at present, is checked before must looking into project, thrombus for operation consent
Project and monitoring clinical oral administration anticoagulant patient.Blood coagulation four include prothrombin time, activated partial thromboplastin time,
Thrombin time, fibrinogen.End-point method of four compared to blood coagulation, thrombelastogram can dynamically reflect coagulation factor,
Fibrin, platelet function and fibrinolytic situation, and the time is greatly shortened, and general more than ten minutes can obtain result.
But Probe-detection methods used by current thrombelastogram instrument are applied for a patent by offshore company, and domestic clinical research urgent need is opened
The completely new dynamic testing method for sending out thrombelastogram a kind of, so that thrombelastogram detection is promoted and developed in China.
Summary of the invention
For background technique problem encountered, thrombus is continuously measured using air pressure the purpose of the present invention is to provide a kind of
The detection method and its dedicated test cup of elastic force figure change China's thrombelastogram instrument market and only have showing for foreign technology and instrument
Shape.
In order to achieve the above object, the present invention adopts the following technical scheme: a kind of air pressure detection method of thrombelastogram,
It is characterized in that, described, detection method includes the following steps:
Blood sample merging to be detected is divided into the two-part detection cup in left and right by Step 1. with isolation bar, is then passed through
Two butyl rubber plugs will test cup sealing；
Step 2. is inserted into butyl rubber plug using two hollow needles respectively, and the hollow needle on right side is made by closing solenoid valve
The air of this side is in sealing state；
Step 3. regularly adjusts right side by operating precise micro air pump, while gas micro-pressure sensor is uninterrupted
Record surveys the gas pressure value in 1 inner sealing space of cup；
All data for being recorded are depicted whole during micro-pressure sensor is solidified retrogradation with blood sample by Step 4.
The tonogram of a coagulation process, i.e. thrombelastogram.
Further, it is equipped with isolation bar among the detection cup, the isolation bar bottom is described from detection cup bottom of a cup 3-5mm
Detection cup upper end sets the air sealing guaranteed in detection cup there are two butyl rubber plug.
Further, two hollow needles arranged vertically are inserted on the butyl rubber plug, the hollow needle upper end is connected with two
The horizontally disposed hollow pipe of root, the end of the hollow pipe are equipped with air filter, prevent blood sample quality to be detected by
To influence.
Further, on the side hollow pipe from connect hollow pin position to the air filter of hollow pipe end according to
The secondary air pumping pipe and electromagnetic gas valve for being equipped with gas micro-pressure sensor, arranging vertically can use the gas that air pump changes detection cup
Pressure, while sensor records each measurement data.
Further, the air pumping pipe is successively arranged precise micro air pump and air filter from bottom to up, guarantees blood sample
Product are not by air pollution.
Detailed description of the invention
Fig. 1 is that air pressure of the present invention continuously measures detection cup structure chart used in thrombelastogram；
Fig. 2 is the detection method schematic diagram that air pressure of the present invention continuously measures thrombelastogram；
The drawing reference numeral of specific embodiment illustrates:
1, detection cup, 2, isolation bar, the 3, first butyl rubber plug, the 4, second butyl rubber plug, 5, blood sample, 6, first is hollow
Needle, the 7, first hollow pipe, the 8, first air filter, the 9, second hollow needle, the 10, second hollow pipe, 11, gas minute-pressure sensing
Device, 12, precise micro air pump, 13, electromagnetic gas valve, the 14, second air filter, 15, third air filter.
Specific embodiment
Purpose, structure, feature and effect in order to better understand the present invention etc., now in conjunction with attached drawing and specific embodiment party
The invention will be further described for formula.
Detection cup used in thrombelastogram is continuously measured for a kind of air pressure of the invention as shown in Figure 1 comprising by being isolated
Muscle 2 will test the chamber that cup 1 is divided into the connection of two bottoms, and the top of two chambers is installed with 3 He of the first butyl rubber plug respectively
The sealing of second butyl rubber plug 4, the blood sample 5 of acquisition are stored in the bottom of detection cup 1.
As Fig. 2 show the detection method that a kind of air pressure of the invention continuously measures thrombelastogram comprising first is empty
Heart needle 6 is inserted into the first butyl rubber plug 3, and the other end of the first hollow needle 6 is installed with the first hollow pipe 7, and the first hollow pipe 7 passes through
First air filter 8 is communicated with atmosphere, and the second hollow needle 9 is inserted into the second butyl rubber plug 4, the other end of the second hollow needle 9
It is installed with the second hollow pipe 10, the second air hose 10 passes through electromagnetic gas valve 13 and the second air filter 14 is communicated with atmosphere, empty
Gas micro-pressure sensor 11 and precise micro air pump 12 are installed on heart pipe 10, another interface of precise micro air pump 12 is installed with
The other end of third air filter 15, third air filter 15 is communicated with atmosphere.
The specific embodiment of the invention is as follows, after detection cup 1 sucks blood sample 5, the first hollow needle 6 and second is hollow
Needle 9 is inserted into respectively in the first butyl rubber plug 3 and the second butyl rubber plug 4, and at this moment closing electromagnetic gas valve 13 makes the sky on 1 right side of detection cup
Sealing gland is closed, and starting 12 regularity of precise micro air pump increases and decreases the gas pressure in 1 inner sealing space of detection cup, while gas
11 uninterrupted recording of micro-pressure sensor surveys the gas pressure value in 1 inner sealing space of cup, with the constantly solidification retrogradation of blood sample 5
Power dropping is moved, the data that gas micro-pressure sensor 11 detects every time also constantly increase, then as blood sample 5 is constantly fine
It is molten and move power rising, the data that gas micro-pressure sensor 11 detects every time also constantly reduce, to depict entire blood coagulation
Process.
Be described in detail above be only the preferred embodiments of the invention explanation, non-therefore limitation the scope of the patents of the invention,
So all equivalence techniques with carried out by this creation specification and diagramatic content change, it is both contained in the scope of the patents of the invention
It is interior.
Claims (5)
1. a kind of air pressure detection method of thrombelastogram, which is characterized in that described detection method includes the following steps:
Blood sample merging to be detected is divided into the two-part detection cup in left and right by Step 1. with isolation bar, then passes through two
Butyl rubber plug will test cup sealing；
Step 2. is inserted into butyl rubber plug using two hollow needles respectively, and the hollow needle on right side is made this by closing solenoid valve
The air of side is in sealing state；
Step 3. regularly adjusts right side, while gas micro-pressure sensor uninterrupted recording by operating precise micro air pump
Survey the gas pressure value in 1 inner sealing space of cup；
Micro-pressure sensor is depicted entire coagulate as blood sample solidifies all data being recorded during retrogradation by Step 4.
The tonogram of blood process, i.e. thrombelastogram.
2. a kind of air pressure detection method dedicated test cup of thrombelastogram according to claim 1, it is characterised in that: institute
It states and is equipped with isolation bar among detection cup, the isolation bar bottom is from detection cup bottom of a cup 3-5mm, there are two the detection cup upper end is set
Butyl rubber plug.
3. a kind of air pressure detection method dedicated test cup of thrombelastogram according to claim 2, it is characterised in that: institute
State and be inserted with two hollow needles arranged vertically on butyl rubber plug, the hollow needle upper end be connected with two it is horizontally disposed hollow
The end of pipe, the hollow pipe is equipped with air filter.
4. a kind of air pressure detection method dedicated test cup of thrombelastogram according to claim 2, it is characterised in that: institute
It states and is passed on the hollow pipe of side from the hollow pin position of connection to gas minute-pressure is successively arranged the air filter of hollow pipe end
Sensor, the air pumping pipe arranged vertically and electromagnetic gas valve.
5. a kind of air pressure detection method dedicated test cup of thrombelastogram according to claim 4, it is characterised in that: institute
It states air pumping pipe and is successively arranged precise micro air pump and air filter from bottom to up.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610106327.6A CN105738247B (en) | 2016-02-26 | 2016-02-26 | A kind of the air pressure detection method and its dedicated test cup of thrombelastogram |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610106327.6A CN105738247B (en) | 2016-02-26 | 2016-02-26 | A kind of the air pressure detection method and its dedicated test cup of thrombelastogram |
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| Publication Number | Publication Date |
|---|---|
| CN105738247A CN105738247A (en) | 2016-07-06 |
| CN105738247B true CN105738247B (en) | 2019-02-01 |
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| CN201610106327.6A Active CN105738247B (en) | 2016-02-26 | 2016-02-26 | A kind of the air pressure detection method and its dedicated test cup of thrombelastogram |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107462628A (en) * | 2017-09-14 | 2017-12-12 | 重庆南方数控设备有限责任公司 | A kind of thrombus detection device for elasticity and detection method based on magnetic |
| CN111912737B (en) * | 2019-05-07 | 2023-09-26 | 重庆南方数控设备有限责任公司 | Method and device for detecting solidification of viscoelastic solution |
| CN110261589B (en) * | 2019-07-18 | 2021-07-06 | 深圳优迪生物技术有限公司 | Thrombelastogram instrument based on micro-resistance |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3911728A (en) * | 1973-02-19 | 1975-10-14 | Daillet S A Ets | Coagulation detection apparatus |
| US4780418A (en) * | 1985-11-19 | 1988-10-25 | Michael Kratzer | Method and apparatus for measuring the aggregation of blood platelets or the coagulation of blood |
| CN1239775A (en) * | 1998-06-23 | 1999-12-29 | 山东工业大学 | Measurement method and device for non-anticoagulant apparent viscosity of blood |
| CN202229992U (en) * | 2011-10-25 | 2012-05-23 | 中国石油天然气股份有限公司 | Device breaking through vacuity gelometry |
| CN103245774A (en) * | 2012-02-07 | 2013-08-14 | 奥索临床诊断有限公司 | Method for determining centrifugal blood conditions through measured pressure |
-
2016
- 2016-02-26 CN CN201610106327.6A patent/CN105738247B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3911728A (en) * | 1973-02-19 | 1975-10-14 | Daillet S A Ets | Coagulation detection apparatus |
| US4780418A (en) * | 1985-11-19 | 1988-10-25 | Michael Kratzer | Method and apparatus for measuring the aggregation of blood platelets or the coagulation of blood |
| CN1239775A (en) * | 1998-06-23 | 1999-12-29 | 山东工业大学 | Measurement method and device for non-anticoagulant apparent viscosity of blood |
| CN202229992U (en) * | 2011-10-25 | 2012-05-23 | 中国石油天然气股份有限公司 | Device breaking through vacuity gelometry |
| CN103245774A (en) * | 2012-02-07 | 2013-08-14 | 奥索临床诊断有限公司 | Method for determining centrifugal blood conditions through measured pressure |
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| CN105738247A (en) | 2016-07-06 |
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Effective date of registration: 20161229 Address after: 430050 Hubei City, Wuhan District, Hanyang District, the city is the number of street, room 92, No. 302 Applicant after: Liu Yong Address before: 430000 Hubei province Wuhan Hannan Economic Development Zone (Wuhan high source Biological Technology Development Co. Ltd.) No. 2 building 1-2 Applicant before: WUHAN DONGFANG HUAKANG TECHNOLOGY CO., LTD. |
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Effective date of registration: 20170623 Address after: 200001, room 1, building 105, 311 Sinan Road, Shanghai, Huangpu District Applicant after: Shanghai Biological Technology Co., Ltd. Address before: 430050 Hubei City, Wuhan District, Hanyang District, the city is the number of street, room 92, No. 302 Applicant before: Liu Yong |
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