CN105727008A - Sheep distemper modified treatment qingwen baidu powder traditional Chinese medicine preparation - Google Patents
Sheep distemper modified treatment qingwen baidu powder traditional Chinese medicine preparation Download PDFInfo
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- CN105727008A CN105727008A CN201410760172.9A CN201410760172A CN105727008A CN 105727008 A CN105727008 A CN 105727008A CN 201410760172 A CN201410760172 A CN 201410760172A CN 105727008 A CN105727008 A CN 105727008A
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Abstract
The present invention discloses a sheep distemper modified treatment qingwen baidu powder traditional Chinese medicine preparation which is prepared from the following components: 139 parts scutellaria baicalensis, 139 parts of cortex moutan, 279 parts of gypsum, 15 parts of gardenia, 149 parts of licorice, 209 parts of bamboo leaves, 169 parts of scrophularia ningpoensis, 309 parts of forsythia, 309 parts of rhizoma anemarrhenae, 25 parts of red peony, 119 parts of platycodon grandiflorum, 209 parts of Codonopsis pilosula, 209 parts of honeysuckle, 127 parts of radix isatidis, 135 parts of Andrographis paniculata, 120 parts of radix angelicae, 125 parts of ephedra, 130 parts of bupleurum and 120 parts of almond by Chinese herbal medicine compatibility and decoction. According to the etiology and pathogenesis and the principle of rational use of the medicines and treatment of both symptoms and root causes, the root causes are mainly treated. The traditional Chinese medicines scutellaria baicalensis, Andrographis paniculata, gypsum, gardenia, bamboo leaves and honeysuckle can clear liver heat, the platycodon grandiflorum, radix angelicae, rhizoma anemarrhenae, scrophularia ningpoensis and forsythia can eliminate phlegm and relieve cough, the ephedra and bupleurum has the effect of relieving exterior syndrome and reorganizing, and diseases can be controlled effectively. The modified treatment qingwen baidu powder traditional Chinese medicine preparation is respectively implanted in a culture base mixed with a disease material for culturing for 24 hours at 37 DEG C in an incubator. Culture results are observed to find that the modified treatment qingwen baidu powder traditional Chinese medicine preparation has a strong inhibitory effect on disease bacteria.
Description
Technical field
The present invention relates to domestic animal technical field of traditional Chinese medicine preparation, be specifically related to a kind of antipyretic and antitoxic powder plus-minus Chinese medicine preparation treatment sheep distemper disease Chinese medicine preparation.
Background technology
In recent years, people's dietary structure changes, and the demand of Carnis caprae seu ovis is increasing, and along with the cultivation scale of meat sheep increases sharply, some new changes also occurs in its disease.Pathogenesis etiology is mainly pathogenic microorganism factor to be caused, and is common in pathogenic PPR virus and streptococcus pneumoniae causes the large-area inflammation in Pulmonis caprae seu ovis portion.Characteristics of incidence: sheep Pestivirus is under the jurisdiction of Paramyxoviridae Morbillivirus, virus presents pleomorphism feature, and main manifestations is coarse spherical, and granule is relatively larger, and nucleocapsid is spiral hollow rod shape and has distinctive subunit, has the existence of cyst membrane；Can at Ren caprae seu ovis, the cell proliferation of fetal lamb, and thus cause the pathological changes of cell, form syncytium on this basis；Goat and sheep are unique natural reservoir (of bird flu viruses) of this virus, and the rate of falling ill of goat is higher, and clinical symptoms performance is more serious；This virus is mainly propagated with 2 kinds of modes of propagation indirectly directly to propagate, and in most cases carries out with respiratory tract infection, mostly occurs in rainy season and dry cold season；In theory, the incubation period of virus is 4～6d, or can extend to 21d.Pathogeny: mycoplasma has parasitism to also exist at ordinary times in or beyond normal carcass in environment, run into climate and big change occurs, weather is sometimes hot and sometimes cold, carcass resistance declines, and pathogen is taken advantage of a weak point, in vivo respiratory mucosa, pulmonary branches tracheal epithelial cell and lung tissue cell amount reproduction, cause lung tissue Cellular inflammatory pathological changes, secondary infection, causes acute or subacute meat sheep pneumonia, and primary disease is mainly through respiratory tract infection.Clinical symptoms: from the angle of clinical symptoms, generally the clinical symptoms ratio of goat is more serious, sheep belong to slight grade.In the primary stage of morbidity, often show as unexpected heating, there is water sample nose liquid, just slowly developed into substantial amounts of glutinous purulence nose liquid later, normal breathing can be impacted, dyspneic situation occurs, once cause that downright bad words occurs in intranasal film, eyes arise that secretions, eyelid is blocked, brings out eye conjunctivitis, be now in the morbidity later stage, often there is cough, the situation of ventral breathing in sick sheep.It addition, sick sheep there is also the situation of diarrhoea, dehydration problem is serious, thus causing that its body weight constantly declines, if the words of heavy ewe, in fact it could happen that the situation of miscarriage.Comprehensive analysis, flock of sheep sickness rate is up to more than 60%, and the probability died of illness is also up to 50%, when occurring that acute disease is sent out, can show as once generating heat dead rapidly.
Summary of the invention
The present invention seeks to for sheep distemper disease multiple, quickly grow, it is more difficult to the problems such as healing, a kind of antipyretic and antitoxic powder plus-minus Chinese medicine preparation treatment sheep distemper disease Chinese medicine preparation is provided, for effectively treating sheep distemper disease or defence, and reach the timid expectorant of heat clearing away, the effect of relieving cough and asthma.
nullAdopt the following technical scheme that a kind of antipyretic and antitoxic powder plus-minus Chinese medicine preparation treatment sheep distemper disease Chinese medicine preparation，It is made up of following weight fraction: Radix Scutellariae 137-140 part、Cortex Moutan 138-140 part、Gypsum Fibrosum 278-280 part、Fructus Gardeniae 14-16 part、Radix Glycyrrhizae 147-152 part、Folium Bambusae 206-213 part、Radix Scrophulariae 167-171 part、Fructus Forsythiae 307-311 part、Rhizoma Anemarrhenae 308-310 part、Radix Paeoniae Rubra 23-26 part、Radix Platycodonis 118-121 part、Radix Codonopsis 208-210 part、Flos Lonicerae 206-215 part、Radix Isatidis 125-130 part、Punching connects 133-137 part、Radix Angelicae Dahuricae 118-123 part、Herba Ephedrae 124-126 part、Radix Bupleuri 128-132 part、Semen Armeniacae Amarum 119-122 part，Above Chinese herbal medicine compatibility decoction.Preferably be made up of following weight fraction: Radix Scutellariae 139 parts, Cortex Moutan 139 parts, 279 parts of Gypsum Fibrosum, Fructus Gardeniae 15 parts, 149 parts of Radix Glycyrrhizae, 209 parts of Folium Bambusae, Radix Scrophulariae 169 parts, Fructus Forsythiae 309 parts, the Rhizoma Anemarrhenae 309 parts, Radix Paeoniae Rubra 25 parts, Radix Platycodonis 119 parts, Radix Codonopsis 209 parts, Flos Lonicerae 209 parts, Radix Isatidis 127 parts, punching connect 135 parts, the Radix Angelicae Dahuricae 120 parts, 125 parts of Herba Ephedrae, Radix Bupleuri 130 parts, 120 parts of Semen Armeniacae Amarum, above Chinese herbal medicine compatibility decoction.
Above scheme has the effect that
1, in change of illness state and therapeutic process, the present invention is according to the cause of disease and pathogeny, rational use of drug, and the principle for the treatment of both the principal and secondary aspects of a disease, to effect a permanent cure.Baikal skullcap root, punching company, Gypsum Fibrosum, Fructus Gardeniae, Folium Bambusae, Flos Lonicerae clearing away lung-heat, the timid phlegm and relieving cough such as Radix Platycodonis, the Radix Angelicae Dahuricae, the Rhizoma Anemarrhenae, Fructus Forsythiae, Radix Scrophulariae, Herba Ephedrae, Radix Bupleuri the effect of unclogging and readjusting of inducing sweat, the state of an illness can be made effectively to be controlled.
2, in the training base be uniformly mixed with pathological material of disease, implant antipyretic and antitoxic powder plus-minus Chinese medicine preparation respectively.At 37 DEG C, incubator is cultivated 24 hours.Observation cultivation results finds: this disease pathogenic bacteria is had relatively high inhibition effect by antipyretic and antitoxic powder plus-minus Chinese medicine preparation.
Detailed description of the invention
Embodiment: from the angle of sheep distemper disease clinical symptoms, generally the clinical symptoms ratio of goat is more serious, sheep belong to slight grade.In the primary stage of morbidity, often show as unexpected heating, there is water sample nose liquid, just slowly developed into substantial amounts of glutinous purulence nose liquid later, normal breathing can be impacted, dyspneic situation occurs, once cause that downright bad words occurs in intranasal film, eyes arise that secretions, eyelid is blocked, brings out eye conjunctivitis, be now in the morbidity later stage, often there is cough, the situation of ventral breathing in sick sheep.It addition, sick sheep there is also the situation of diarrhoea, dehydration problem is serious, thus causing that its body weight constantly declines, if the words of heavy ewe, in fact it could happen that the situation of miscarriage.Comprehensive analysis, flock of sheep sickness rate is up to more than 60%, and the probability died of illness is also up to 50%, when occurring that acute disease is sent out, can show as once generating heat dead rapidly.
Majority of cases finds that oral cavity and bronchia mucosal erosion are downright bad；Bronchopneumonia, apex pulmonis pneumonia；Sometimes visible gangrenosum acne or hemorrhagic enteritis, caecum, colon near-end and rectum occur that characteristic strip is congested, hemorrhage, in zebra shape striped；Sometimes visible lymph node particularly mesenteric lymph node edema, also can there is necrotic lesion in spleen enlargement.There is acidophilia's occlusion body in multinucleated giant cell and cell in the upper visible lung tissue of histology.Special acute case visible bronchopneumonia and ileocecum lobe when cuing open inspection is congested.
In the lung of pathological changes, intestinal tissue, taking out sample, smear staining at random, microscopy finds this sheep Pestivirus.Absorb a small amount of samples to put into and bacteria culture media carries out at 37 DEG C cultivate 24 hours, it has been found that a large amount of yellow color colonies, take out that part bacterium colony makees smear, dyeing, microscopy are further discovered that the streptococcus pneumoniae that this virus a large amount of causes.Separately taking pathological material of disease and be inoculated on mycoplasma culture medium (such as 10% horse serum Martin's agar), visible poor transparent dew drop-wise circular colonies after cultivating 1～2 week at 37 DEG C, there are papillae in central authorities, can carry out judging mycoplasma infection.During smear staining microscopy, thread mycoplasma is that Gram's staining is negative, painted not good；But dye with Ji's nurse Sa, be pleomorphism at high power microscope hypothallus.
The training base be uniformly mixed with pathological material of disease is implanted antipyretic and antitoxic powder plus-minus Chinese medicine preparation respectively.At 37 DEG C, incubator is cultivated 24 hours.Observation cultivation results finds: this disease pathogenic bacteria is had relatively high inhibition effect by antipyretic and antitoxic powder plus-minus Chinese medicine preparation.
Inspection and laboratory diagnosis is cutd open, it is judged that for streptococcus pneumoniae, mycoplasma microbial mixed infection sheep distemper disease case according to clinical symptoms, pathology.
Adopt antipyretic and antitoxic powder plus-minus Chinese medicine preparation treatment sheep distemper disease Chinese medicine preparation, it is made up of following weight fraction: Radix Scutellariae 137-140 gram, Cortex Moutan 138-140 gram, 278-280 gram of Gypsum Fibrosum, Fructus Gardeniae 14-16 gram, 147-152 gram of Radix Glycyrrhizae, 206-213 gram of Folium Bambusae, Radix Scrophulariae 167-171 gram, Fructus Forsythiae 307-311 gram, Rhizoma Anemarrhenae 308-310 gram, Radix Paeoniae Rubra 23-26 gram, Radix Platycodonis 118-121 gram, Radix Codonopsis 208-210 gram, Flos Lonicerae 206-215 gram, Radix Isatidis 125-130 gram, punching connects 133-137 gram, Radix Angelicae Dahuricae 118-123 gram, 124-126 gram of Herba Ephedrae, Radix Bupleuri 128-132 gram, 119-122 gram of Semen Armeniacae Amarum, above Chinese herbal medicine compatibility decoction.Preferably be made up of following weight fraction: Radix Scutellariae 139 grams, Cortex Moutan 139 grams, 279 grams of Gypsum Fibrosum, Fructus Gardeniae 15 grams, 149 grams of Radix Glycyrrhizae, 209 grams of Folium Bambusae, Radix Scrophulariae 169 grams, Fructus Forsythiae 309 grams, the Rhizoma Anemarrhenae 309 grams, Radix Paeoniae Rubra 25 grams, Radix Platycodonis 119 grams, Radix Codonopsis 209 grams, Flos Lonicerae 209 grams, Radix Isatidis 127 grams, punching connect 135 grams, the Radix Angelicae Dahuricae 120 grams, 125 grams of Herba Ephedrae, Radix Bupleuri 130 grams, 120 grams of Semen Armeniacae Amarum, above Chinese herbal medicine compatibility decoction.
In change of illness state and therapeutic process, according to the cause of disease and pathogeny, rational use of drug, the principle for the treatment of both the principal and secondary aspects of a disease, to effect a permanent cure.Baikal skullcap root, punching company, Gypsum Fibrosum, Fructus Gardeniae, Folium Bambusae, Flos Lonicerae clearing away lung-heat, the timid phlegm and relieving cough such as Radix Platycodonis, the Radix Angelicae Dahuricae, the Rhizoma Anemarrhenae, Fructus Forsythiae, Radix Scrophulariae, Herba Ephedrae, Radix Bupleuri the effect of unclogging and readjusting of inducing sweat, the state of an illness can be made effectively to be controlled.
Clinical case:Raise main name: Lee；Morbidity place: meat sheep field, Songxian, Henan.On April 17th, 2013, this sheep raising field cultivation scale becomes sheep 320, calf sheep 65, young sheep 83, and this flock of sheep part sheep falls ill, several 47 of morbidity.Pathogenic factor: introduce a collection of sheep from Hebei (other places) before first quarter moon and raise, these flock of sheep cause batch sheep morbidity through the weather reason such as rainy that turns cold afterwards.Clinical symptoms: body temperature up to 40-42 degree, sick sheep spirit is depressed, loss of appetite, indivedual sheep rapid breathing, cough, nostril stream mucus secretions, there is large-area moist rale in auscultation pulmonary.
Diagnosis: 1, cut open inspection and find that oral cavity and bronchia mucosal erosion are downright bad；Caecum, colon near-end and rectum occur that characteristic strip is congested, hemorrhage and downright bad, in zebra shape striped；There is edema in mesenteric lymph node, and spleen enlargement also has necrosis phenomena.There is acidophilia's occlusion body in multinucleated giant cell and cell in lung tissue.Special acute case visible bronchopneumonia and ileocecum lobe when cuing open inspection is congested.In conjunction with above clinical symptoms, through cuing open inspection and microscopy, the diagnosis of this flock of sheep disease sheep is that the sheep distemper caused by sheep Pestivirus is sick.
Treatment: antipyretic and antitoxic powder plus-minus Chinese medicinal formulae R: Radix Scutellariae 139 grams, Cortex Moutan 139 grams, 279 grams of Gypsum Fibrosum, Fructus Gardeniae 15 grams, 149 grams of Radix Glycyrrhizae, 209 grams of Folium Bambusae, Radix Scrophulariae 169 grams, Fructus Forsythiae 309 grams, the Rhizoma Anemarrhenae 309 grams, Radix Paeoniae Rubra 25 grams, Radix Platycodonis 119 grams, Radix Codonopsis 209 grams, Flos Lonicerae 209 grams, Radix Isatidis 127 grams, punching connect 135 grams, the Radix Angelicae Dahuricae 120 grams, 125 grams of Herba Ephedrae, Radix Bupleuri 130 grams, the Chinese herbal medicine compatibility decoction such as 120 grams of Semen Armeniacae Amarum.
Observation of curative effect: after medication 6 days, the sick sheep symptom of major part is controlled, and after 12 days, whole flock of sheep are almost recovered, again pay a return visit after 21 days, and this flock of sheep disease cattle is all cured.
Claims (2)
- null1. an antipyretic and antitoxic powder plus-minus Chinese medicine preparation treatment sheep distemper disease Chinese medicine preparation，It is characterized in that，It is made up of following weight fraction: Radix Scutellariae 137-140 part、Cortex Moutan 138-140 part、Gypsum Fibrosum 278-280 part、Fructus Gardeniae 14-16 part、Radix Glycyrrhizae 147-152 part、Folium Bambusae 206-213 part、Radix Scrophulariae 167-171 part、Fructus Forsythiae 307-311 part、Rhizoma Anemarrhenae 308-310 part、Radix Paeoniae Rubra 23-26 part、Radix Platycodonis 118-121 part、Radix Codonopsis 208-210 part、Flos Lonicerae 206-215 part、Radix Isatidis 125-130 part、Punching connects 133-137 part、Radix Angelicae Dahuricae 118-123 part、Herba Ephedrae 124-126 part、Radix Bupleuri 128-132 part、Semen Armeniacae Amarum 119-122 part，Above Chinese herbal medicine compatibility decoction.
- 2. antipyretic and antitoxic powder according to claim 1 plus-minus Chinese medicine preparation treatment sheep distemper disease Chinese medicine preparation, it is characterized in that, Radix Scutellariae 139 parts, Cortex Moutan 139 parts, 279 parts of Gypsum Fibrosum, Fructus Gardeniae 15 parts, 149 parts of Radix Glycyrrhizae, 209 parts of Folium Bambusae, Radix Scrophulariae 169 parts, Fructus Forsythiae 309 parts, the Rhizoma Anemarrhenae 309 parts, Radix Paeoniae Rubra 25 parts, Radix Platycodonis 119 parts, Radix Codonopsis 209 parts, Flos Lonicerae 209 parts, Radix Isatidis 127 parts, punching connect 135 parts, the Radix Angelicae Dahuricae 120 parts, 125 parts of Herba Ephedrae, Radix Bupleuri 130 parts, 120 parts of Semen Armeniacae Amarum, above Chinese herbal medicine compatibility decoction.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106215003A (en) * | 2016-08-25 | 2016-12-14 | 陈鹏举 | A kind of Chinese medicine composition treating poultry epidemic febrile disease |
| CN107854629A (en) * | 2017-12-23 | 2018-03-30 | 厦门汇承科技有限公司 | A kind of eliminating pestilence and relieving toxicity Chinese medicine composition for animals and preparation method thereof |
| CN109090356A (en) * | 2018-09-04 | 2018-12-28 | 乡宁县关王庙乡新杰养羊专业合作社 | A kind of meat goat fattening period mixed concentrate formula |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106215003A (en) * | 2016-08-25 | 2016-12-14 | 陈鹏举 | A kind of Chinese medicine composition treating poultry epidemic febrile disease |
| CN107854629A (en) * | 2017-12-23 | 2018-03-30 | 厦门汇承科技有限公司 | A kind of eliminating pestilence and relieving toxicity Chinese medicine composition for animals and preparation method thereof |
| CN109090356A (en) * | 2018-09-04 | 2018-12-28 | 乡宁县关王庙乡新杰养羊专业合作社 | A kind of meat goat fattening period mixed concentrate formula |
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Address after: 450000 No. 16 Beilin Road, Jinshui District, Zhengzhou City, Henan Province Applicant after: Henan University of Animal Husbandry and Economy Address before: 450000 No. 16 Beilin Road, Jinshui District, Zhengzhou City, Henan Province Applicant before: Zhengzhou Husbandry Engineering Higher Training School |
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Application publication date: 20160706 |