CN105726931A - Traditional Chinese medicine preparation for treating chronic heart failure and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for treating chronic heart failure and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to the traditional Chinese medicine field, and more specifically to a traditional Chinese medicine preparation for treating chronic heart failure and a preparation method thereof, which is characterized by the traditional Chinese medicine preparation for treating chronic heart failure is prepared from the following traditional Chinese medicine raw materials, by weight, 10-15 parts of Radix Codonopsis, 15-20 parts of radix et rhizoma salviae miltiorrhizae, 10-15 parts of pseudo-ginseng, 15-20 parts of Radix Astragali, 5-8 parts of flos carthami, 3-5 parts of cassia twig, 5-8 parts of cornu cervi, 5-8 parts of radix ophiopogonis, 10-15 parts of fructus schisandrae chinensis, 2-3 parts of rhizoma atractylodis macrocephalae, 3-5 parts of radix angelicae sinensis, 3-5 parts of radix paeoniae rubra, 3-5 parts of rhizoma coptidis, 3-5 parts of cortex moutan, and 1-2 parts of virgate wormwood. The traditional Chinese medicine preparation for treating chronic heart failure and the preparation method thereof have the advantages that the used traditional Chinese medicines accord with standards of Pharmacopoeia of the People's Republic of China, and the medicines are safe and reliable. The medicines accord with each other in properties, have the efficacy of benefiting heart qi, activating blood circulation to dissipate blood stasis, and inducing dieresis and reducing phlegm, and has characteristics of definite therapeutic effect, fast effectiveness, and high cure rate without side-effect in the treatment of the chronic heart failure.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Chinese medicine preparation treating chronic heart failure and preparation method thereof.
Background technology
Chronic heart failure (CHF) is serious or the end stage eventually a kind of clinical syndrome of various heart disease.The common cause causing CHF is coronary heart disease, hypertension, diabetes and various cardiomyopathys etc., and the heart failure that wherein coronary heart disease causes accounts for first place.
The M & M of CHF remains high, and has close relationship with the clinical course of CHF.2007 China's " diagnosis of chronic congestive heart failure and treatment guidelines " and the Heart failure guide of 2005 U.S. all point out that CHF is a kind of progressive pathological changes, once initiate, even without new cardiac damage, clinic is also at the stabilization sub stage, but still self development.Therefore, U.S.'s heart failure writes the new method of committee's initiative development heart failure classification, and by its order of severity, heart failure is divided into A, B, C, D four-stage.Stage A is " front heart failure stage " (Pre-HeartFailure), the structure of this stage acardia or dysfunction, also without the symptom of heart failure and (or) sign.Being more common in the population at risk occurred frequently (referring mainly to hypertension, coronary heart disease, diabetes etc.) of heart failure, the heart failure in this stage can prevent.Stage B belongs to " front clinical heart failure stage " (Pre-ClinicalHeartFailure), patient has evolved into structural heart disease from symptom and (or) the sign without heart failure, for instance: left ventricular hypertrophy, asymptomatic valvular heart disease, there is MI (myocardial infarction) history etc. in the past.This stage is equivalent to silent heart failure or NYHA cardiac function I grade.Owing to heart failure is a kind of progressive pathological changes, but myocardial remodelling self constantly develops, and therefore, this stage active treatment of patient is of crucial importance, and treat it is crucial that block or delay myocardial remodelling.Stage C is the clinical heart failure stage.The structural heart disease on the existing basis of patient, has symptom and (or) the sign of heart failure in the past or at present；Though or at present without the symptom of heart failure and (or) sign, but once therefore treated in the past.This stage includes NYHA II, III grade and IV grade of cardiac function patient of part.Stage D is the intractable whole heart failure stage in latter stage.Patient has Progressive symmetric erythrokeratodermia structural heart disease, though through positive medical treatment, still having symptom, and need special intervention during rest.
As can be seen here, for heart failure stage B, before the symptoms of heart failure of myocardial infarction or left ventricular hypertrophy patient occurs, early stage takes remedy measures, it is possible to decrease the M & M of heart failure.
Chinese medicine is cured the disease in process long-term, have accumulated rich experience.Without the name of " heart failure " in traditional Chinese medical science traditional literature, according to its Clinical symptoms, relate to the categories such as the traditional Chinese medical science " the syndrome of dyspnea ", " edema ", " cardiopalmus ", " palpitation with a distress feeling ", " phlegm retention ", " obstruction of heart-QI ".Great majority research is thought, primary disease belongs to the card of deficiency in origin and excess in superficiality, simulataneous insufficiency and excessive, declines for this with motive deficiency of heart-YANG, and the blood vessels stasis of blood is stagnant, fluid-retention stagnating in the interior, expectorant are turbid does not turn to mark.
In recent years, the sickness rate of heart failure and case fatality rate present the trend of constantly rising, and consequent medical expense and burden on society also increase sharply, and within 2005, U.S.'s CHF patient reaches 5,500,000, are used directly or indirectly in the expense for the treatment of CHF up to 27,900,000,000 dollars.China's result to urban and rural residents' totally 15518 people's random sampling in 35～74 years old: heart failure prevalence is 0.9%, there are about 4,000,000 patients with heart failure by calculating, and wherein male is 0.7%, and women is 1.0%.Framingham studies display, CHF5 annual survival rate, and male is 25%, and women is 38%, and patient with severe symptoms was generally survived less than 1 year.According to 42, China some areas hospital, 3 annual sections in 1980,1990,2000, to the heart failure inpatient Retrospective review that totally 10714 examples are made, in the cause of disease, coronary heart disease is risen to 45.6% in 2000 by 36.8% in 1980, occupies first of the various cause of disease；15 hospitals totally 3169 patients with heart failure in 8 cities have been investigated by one research of the Japan adjacent with China, it has been found that hat
Cardiopathia also accounts for space of top prominence (33.5%) in the heart failure cause of disease；Framingham studies discovery, when the age by 40 years old time, crowd occurs the danger of heart failure substantially to increase (male: 21%, women: 20%), and this danger and myocardial ischemia and blood pressure level are closely related.
The conventional medicament for the treatment of CHF mainly includes diuretic, ACEI (angiotensin converting enzyme inhibitor) class, vasodilation, cardiac tonic, Myocardial nutrient, calcium channel blocker etc., but fundamentally do not improve the quality of life of patient, also fail to effectively reduce the mortality rate of CHF, clinical practice there is also problems.Along with the understanding that CHF occurs and develops basic pathology mechanism myocardial remodelling, traditional heart tonifying, diuresis, expansion blood vessel conventional therapy theory progressively desalinate, improve symptom from the pharmaceutical practice of short-term, be gradually converted into strategy long-term, prosthetic and to the pathogenetic intervention of CHF.
Summary of the invention
According to above the deficiencies in the prior art, the present invention provides a kind of Chinese medicine preparation treating chronic heart failure and preparation method thereof, and it is evident in efficacy, safe and reliable, have no side effect, and has wide potential applicability in clinical practice.
A kind of Chinese medicine preparation treating chronic heart failure of the present invention, according to parts by weight meter, formulated by following raw material of Chinese medicine: Radix Codonopsis 10～15 parts, Radix Salviae Miltiorrhizae 15～20 parts, Radix Notoginseng 10～15 parts, the Radix Astragali 15～20 parts, 5～8 parts of Flos Carthami, Ramulus Cinnamomi 3～5 parts, 5～8 parts of Cornu Cervi, Radix Ophiopogonis 5～8 parts, Fructus Schisandrae Chinensis 10～15 parts, the Rhizoma Atractylodis Macrocephalae 2～3 parts, Radix Angelicae Sinensis 3～5 parts, Radix Paeoniae Rubra 3～5 parts, Rhizoma Coptidis 3～5 parts, Cortex Moutan 3～5 parts and Artemisia anethoicles Mattf 1～2 part.
Wherein, it is preferable that scheme is as follows:
According to parts by weight meter, formulated by following raw material of Chinese medicine: Radix Codonopsis 10 parts, Radix Salviae Miltiorrhizae 15 parts, Radix Notoginseng 10 parts, the Radix Astragali 15 parts, 5 parts of Flos Carthami, Ramulus Cinnamomi 3 parts, 5 parts of Cornu Cervi, Radix Ophiopogonis 5 parts, Fructus Schisandrae Chinensis 10 parts, the Rhizoma Atractylodis Macrocephalae 2 parts, Radix Angelicae Sinensis 3 parts, Radix Paeoniae Rubra 3 parts, Rhizoma Coptidis 3 parts, Cortex Moutan 3 parts and Artemisia anethoicles Mattf 1 part.
Can also according to parts by weight meter, formulated by following raw material of Chinese medicine: Radix Codonopsis 15 parts, Radix Salviae Miltiorrhizae 20 parts, Radix Notoginseng 15 parts, the Radix Astragali 20 parts, 8 parts of Flos Carthami, Ramulus Cinnamomi 5 parts, 8 parts of Cornu Cervi, Radix Ophiopogonis 8 parts, Fructus Schisandrae Chinensis 15 parts, the Rhizoma Atractylodis Macrocephalae 3 parts, Radix Angelicae Sinensis 5 parts, Radix Paeoniae Rubra 5 parts, Rhizoma Coptidis 5 parts, Cortex Moutan 5 parts and Artemisia anethoicles Mattf 2 parts.
The preparation method of the Chinese medicine preparation for the treatment of chronic heart failure of the present invention, prepare in accordance with the following methods: weigh raw material of Chinese medicine according to formula and join in container, add water and cover powder immersion 10～20 minutes, add water and do not have powder 3～5 centimetres, decoct with high heat and use slow fire boiling again instead 20～30 minutes to boiling, take filtrate；Then adding water and do not have powder 3～5 centimetres, decoct with high heat and use slow fire boiling again instead 15～20 minutes to boiling, then removing slag takes filtrate, and twice filtrate merges.
During use, each 200～300ml, sooner or later respectively once.
Pharmacology analysis:
Radix Codonopsis: property is put down, sweet in the mouth, there is effect of invigorating the spleen and replenishing QI, spleen invigorating lung benefiting, anticancer, blood pressure lowering, anti-hypoxia, defying age, body immunity can also be strengthened, improve the activity of superoxide dismutase, strengthen the ability eliminating free radical, there is the effect of Gastrointestinal motility adjustment, antiulcer, gastric acid secretion inhibiting, reduction pepsin activity.Have a delicate constitution, insufficiency of vital energy and blood, shallow complexion, and puerperal asthenia person should eat after being ill；Deficiency of spleen-QI and stomach-QI, tired, limbs fatigue, anorexia and loose stool, chronic diarrhea, insufficiency of lung-QI, tachypnea of coughing, deficiency of vital energy and physically weak, it is easy to flu；Qi and blood deficiency person should eat；Chronic nephritis proteinuria person should eat；Chronic anaemia, chlorosis, leukemia, thrombocytopenic purpura and rickets patient should eat.
Radix Salviae Miltiorrhizae: bitter in the mouth, cold nature.Root is used as medicine, and containing TANSHINONES, for robustness emmenagogue, has blood stasis dispelling, tissue regeneration promoting, invigorates blood circulation, the effectiveness such as regulating menstruation, for gynecological's key medicine, cures mainly metrorrhagia, menoxenia, blood stasis, stomachache, dysmenorrhoea, amenorrhea, mausoleum pain.Treatment coronary heart disease there is good result.In addition also controlling the weak insomnia of nerve, arthralgia, anemia, mastitis, lymphadenitis, arthritis, furuncle pain is swollen, erysipelas, acute, chronic hepatitis, nephropyelitis, traumatic injury, and advanced schistosomiasis hepatosplenomegaly is insane.
Radix Notoginseng: sweet micro-hardship, temperature, nontoxic.Enter liver, stomach, double enter the heart, large intestine.Hemostasis, dissipating blood stasis, detumescence, analgesic therapy.Control haematemesis, hemoptysis, epistaxis, have blood in stool, dysentery, metrorrhagia, lump in the abdomen, puerperal blood faints, retention of lochia, fall and flutter blood stasis, traumatic hemorrhage, carbuncle pain.
The Radix Astragali: invigorating QI to consolidate the body surface resistance, expelling pus and toxin by strengthening QI, diuresis, granulation promoting., chronic diarrhea proctoptosis, spontaneous perspiration, edema weak for the deficiency of vital energy, sub-official prolapsus, chronic nephritis proteinuria, diabetes, open sore part disunion of a specified duration.
Flos Carthami: pungent, temperature, nontoxic.Enter the heart, Liver Channel.Promoting blood circulation to restore menstrual flow, blood stasis removing pain relieving.Controlling amenorrhea, lump in the abdomen, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, injury from falling down.
Ramulus Cinnamomi: nature and flavor are pungent, sweet, temperature, enter lung, the heart, bladder warp, it is cure mainly the drugs for dispelling internal cold that interior cold is conventional, there is effect of complement sun, promoting blood circulation, warming the spleen and stomach, often with tonifying liver renal drug, fill blood medicine compatibility, treatment insufficiency of kidney-YANG, decline of the fire from the gate of life, cold extremities faint pulse, treat coldness and pain in the epigastrium, arthralgia due to cold lumbago with other drugs for dispelling internal cold compatibility, there is the effect of significantly analgesia and anti-cancer and cancer-preventing.
Cornu Cervi: salty in the mouth, tepor, nontoxic.Enter liver, kidney channel.Promoting the circulation of blood, detumescence, kidney tonifying.Controlling sore swollen toxin, blood stasis is had a pain, asthenia internal injury, lumbar vertebrae pain.
Radix Ophiopogonis: sweet, micro-hardship, it is slightly cold.GUIXIN, lung, stomach warp.YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough, deficiency of YIN consumptive disease is coughed, sore throat pharyngalgia, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation.
Fructus Schisandrae Chinensis: astringe the lung, nourishing kidney, promote the production of body fluid, receive antiperspirant, arresting seminal emission.Controlling the deficiency of the lung to breath with cough, xerostomia is made thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery.Fructus Schisandrae Chinensis has vasodilative effect.Schizandrin, schisandrin C, deoxyschisandrin etc. shrink in vitro Canis familiaris L. Mesenteric artery all inhibitory action, can increase arteries and veins Mus isolated heart and anesthesia Canis familiaris L. coronary flow.Feed rabbit with Radix Schisandrae Bicoloris and can regulate myocardial cell and the energy metabolism of the heart, renal arterioles, improve myocardial metabolism enzymatic activity, improve nutrition and the function of cardiac muscle.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth, sweet, warm in nature.Return spleen, stomach warp.Invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement.
Radix Angelicae Sinensis: sweet in the mouth, temperature.Return liver, the heart, spleen channel.Enrich blood；Invigorate blood circulation；Menstruction regulating and pain relieving；Moisturize laxation.Cure mainly all cards of blood deficiency: menoxenia；Amenorrhea；Dysmenorrhea；Lump in the abdomen knot is poly-；Metrorrhagia；Asthenia cold abdominalgia；Flaccidity syndrome and arthralgia syndrome；Numbness of the skin；Dryness of the intestine dyschezia；Weight after bloody dysentery；Ulcer sores；Injury from falling down.
Radix Paeoniae Rubra: bitter, is slightly cold.Return Liver Channel.Clearing away heat and cooling blood；Blood circulation promoting and blood stasis dispelling.Main maculae caused by violent heat pathogen；Hematemesis and epistaxis；Discharging fresh blood stool；Conjunctival congestion and swelling pain；Carbuncle skin infection；Amenorrhea；Dysmenorrhea；Metrorrhagia and leukorrhagia stranguria with turbid discharge；The stagnant hypochondriac pain of the stasis of blood；Hernia abdominal mass is gathered；Injury from falling down.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, injury from falling down, carbuncle skin infection.
Rhizoma Coptidis: pathogenic fire purging, dampness, removing toxic substances, parasite killing.Row pyretic toxicity when controlling, typhoid fever, intenseness of heat is vexed, feeling of fullness vomiting, bacillary dysentery, and diarrhea of heat type is suffered from abdominal pain, and lung knot is pressed, and tells, is defeated in battle, hematochezia, quenches one's thirst, infantile malnutrition, ascariasis, pertussis, laryngopharynx swelling and pain, acute catarrhal conjunctivitis, aphtha, skin sore, eczema, the burning hot wound of soup.
Cortex Moutan: arduous；Cool；It is slightly cold.GUIXIN；Liver；Kidney；Lung meridian.Heat clearing away；Promoting blood circulation to remove blood stasis.Control the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases；Send out speckle；Tell nosebleed；Pathogenic bacteria later stage brimful of tears hot Fu Yin distribution heat；Deficiency of YIN osteopyrexia and fever；Amenorrhea due to stagnation of blood；Dysmenorrhea；Carbuncle sore tumefacting virus；Fall and flutter the pain of injury；Beriberoid pyretic arthralgia.
Artemisia anethoicles Mattf: mildly bitter flavor；Micro-pungent；Cold nature.Return spleen；Stomach；Bladder warp.Clearing away heat-damp and promoting diuresis, jaundice eliminating；Cure mainly jaundice oliguria, dysuria, eczema pruritus, infectious jaundice type hepatitis.
It is an advantage of the current invention that the Chinese medicine used meets Pharmacopoeia of People's Republic of China regulation, safety of medicine is reliable.All medicine phases and there is the tonification motive, effect, the features such as treatment chronic heart failure has determined curative effect, instant effect, cure rate is high, have no side effect such as blood circulation promoting and blood stasis dispelling, diuretic reduce phlegm.
Outcome measure:
1, case selection:
As treatment chronic heart failure medicine, select chronic heart failure 100 example carry out clinical observation, wherein male 52 examples, women 48 example, age 45-85 year, 55 years old mean age, course of disease 1-10, average 1.2 years.
2, medicine for treatment:
Treatment group patient takes medicine of the present invention, each 200～300ml, sooner or later each once within 7 days, be a course for the treatment of, take continuously 3-4 the course for the treatment of according to the state of an illness, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3, Outcome measure:
According to USA New York cardiology meeting heart failure grade scale (NYHA classification), without heart failure person BNP<80ng/L, I grade of person BNP95～221ng/L of cardiac function, II grade of patient B NP221～459ng/L of cardiac function, Ⅲcardiac function patient B NP459～1006ng/L, IV grade of patient B NP>=1006ng/L of cardiac function.At present, in the world the positive threshold value of patients with heart failure BNP is decided to be 100ng/L, when BNP measured value is below normal value, it is believed that heart failure can be got rid of.
Effective: clinical symptoms disappears substantially, test chamber checks that each index of correlation is close to normal level, BNP < 100ng/L.
Effective: clinical symptom relief, test chamber checks that each index of correlation makes moderate progress, and NYHA classification promotes to improvement direction, and sign has improvement.
Invalid: clinical symptoms is without being clearly better or increasing the weight of.
4, therapeutic outcome:
Effective 30 examples, effective 62 examples, invalid 8 examples, total effective rate is 92%.
It is exemplified below a model case:
Lee, female, 71 years old, people from Qingdao, in more than 20 years of chronic heart failure, heart rate 85 beats/min, blood pressure 145/85mmHg, cardiac function NYHA III grade, dyspnea, left cardiac ejection fraction 37%, 24h urine volume was about 620ml, hydrosarca, body weight 78.6kg.Before treatment, 24h furosemide consumption 1600mg and spironolactone consumption are 180mg, and blood urea nitrogen 27.7mmol/l, serum creatinine 458.7mmol/l, blood electrolyte often gets muddled.When taking first course for the treatment of of invention formulation, heart rate 70 beats/min, cardiac function is improved as II grade, left cardiac ejection fraction 48%, and body weight is 70kg, day urine volume be about 1440ml, blood pressure 135/72mmHg, dyspnea and edema are obviously improved.Following up a case by regular visits to second course for the treatment of, These parameters is improved further.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1:
A kind of Chinese medicine preparation treating chronic heart failure, according to parts by weight meter, formulated by following raw material of Chinese medicine: Radix Codonopsis 10 parts, Radix Salviae Miltiorrhizae 15 parts, Radix Notoginseng 10 parts, the Radix Astragali 15 parts, 5 parts of Flos Carthami, Ramulus Cinnamomi 3 parts, 5 parts of Cornu Cervi, Radix Ophiopogonis 5 parts, Fructus Schisandrae Chinensis 10 parts, the Rhizoma Atractylodis Macrocephalae 2 parts, Radix Angelicae Sinensis 3 parts, Radix Paeoniae Rubra 3 parts, Rhizoma Coptidis 3 parts, Cortex Moutan 3 parts and Artemisia anethoicles Mattf 1 part.
Embodiment 2:
: a kind of Chinese medicine preparation treating chronic heart failure, according to parts by weight meter, formulated by following raw material of Chinese medicine: Radix Codonopsis 15 parts, Radix Salviae Miltiorrhizae 20 parts, Radix Notoginseng 15 parts, the Radix Astragali 20 parts, 8 parts of Flos Carthami, Ramulus Cinnamomi 5 parts, 8 parts of Cornu Cervi, Radix Ophiopogonis 8 parts, Fructus Schisandrae Chinensis 15 parts, the Rhizoma Atractylodis Macrocephalae 3 parts, Radix Angelicae Sinensis 5 parts, Radix Paeoniae Rubra 5 parts, Rhizoma Coptidis 5 parts, Cortex Moutan 5 parts and Artemisia anethoicles Mattf 2 parts.
Embodiment 3:
Formula described in embodiment 1 prepares the Chinese medicine preparation for the treatment of chronic heart failure in accordance with the following methods: weighs raw material of Chinese medicine according to formula and joins in container, add water and cover powder immersion 10 minutes, add water and do not have powder 3 centimetres, decoct with high heat and use slow fire boiling again instead 20 minutes to boiling, take filtrate；Then adding water and do not have powder 3 centimetres, decoct with high heat and use slow fire boiling again instead 15 minutes to boiling, then removing slag takes filtrate, and twice filtrate merges.
Embodiment 4:
Formula described in embodiment 2 prepares the Chinese medicine preparation for the treatment of chronic heart failure in accordance with the following methods: weighs raw material of Chinese medicine according to formula and joins in container, add water and cover powder immersion 20 minutes, add water and do not have powder 5 centimetres, decoct with high heat and use slow fire boiling again instead 30 minutes to boiling, take filtrate；Then adding water and do not have powder 5 centimetres, decoct with high heat and use slow fire boiling again instead 20 minutes to boiling, then removing slag takes filtrate, and twice filtrate merges.
Claims (4)
1. the Chinese medicine preparation treating chronic heart failure, it is characterized in that according to parts by weight meter, formulated by following raw material of Chinese medicine: Radix Codonopsis 10～15 parts, Radix Salviae Miltiorrhizae 15～20 parts, Radix Notoginseng 10～15 parts, the Radix Astragali 15～20 parts, 5～8 parts of Flos Carthami, Ramulus Cinnamomi 3～5 parts, 5～8 parts of Cornu Cervi, Radix Ophiopogonis 5～8 parts, Fructus Schisandrae Chinensis 10～15 parts, the Rhizoma Atractylodis Macrocephalae 2～3 parts, Radix Angelicae Sinensis 3～5 parts, Radix Paeoniae Rubra 3～5 parts, Rhizoma Coptidis 3～5 parts, Cortex Moutan 3～5 parts and Artemisia anethoicles Mattf 1～2 part.
2. a kind of Chinese medicine preparation treating chronic heart failure according to claim 1, it is characterized in that according to parts by weight meter, formulated by following raw material of Chinese medicine: Radix Codonopsis 10 parts, Radix Salviae Miltiorrhizae 15 parts, Radix Notoginseng 10 parts, the Radix Astragali 15 parts, 5 parts of Flos Carthami, Ramulus Cinnamomi 3 parts, 5 parts of Cornu Cervi, Radix Ophiopogonis 5 parts, Fructus Schisandrae Chinensis 10 parts, the Rhizoma Atractylodis Macrocephalae 2 parts, Radix Angelicae Sinensis 3 parts, Radix Paeoniae Rubra 3 parts, Rhizoma Coptidis 3 parts, Cortex Moutan 3 parts and Artemisia anethoicles Mattf 1 part.
3. a kind of Chinese medicine preparation treating chronic heart failure according to claim 1, it is characterized in that according to parts by weight meter, formulated by following raw material of Chinese medicine: Radix Codonopsis 15 parts, Radix Salviae Miltiorrhizae 20 parts, Radix Notoginseng 15 parts, the Radix Astragali 20 parts, 8 parts of Flos Carthami, Ramulus Cinnamomi 5 parts, 8 parts of Cornu Cervi, Radix Ophiopogonis 8 parts, Fructus Schisandrae Chinensis 15 parts, the Rhizoma Atractylodis Macrocephalae 3 parts, Radix Angelicae Sinensis 5 parts, Radix Paeoniae Rubra 5 parts, Rhizoma Coptidis 5 parts, Cortex Moutan 5 parts and Artemisia anethoicles Mattf 2 parts.
4. the preparation method of the Chinese medicine preparation of the treatment chronic heart failure described in a claim 1, it is characterized in that preparing in accordance with the following methods: weigh raw material of Chinese medicine according to formula and join in container, add water and cover powder immersion 10～20 minutes, add water and do not have powder 3～5 centimetres, decoct with high heat and use slow fire boiling again instead 20～30 minutes to boiling, take filtrate；Then adding water and do not have powder 3～5 centimetres, decoct with high heat and use slow fire boiling again instead 15～20 minutes to boiling, then removing slag takes filtrate, and twice filtrate merges.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104587173A (en) * | 2014-12-26 | 2015-05-06 | 青岛市市立医院 | Traditional Chinese medicine preparation for treating chronic heart failure, as well preparation method thereof |
| CN106880826A (en) * | 2017-03-15 | 2017-06-23 | 付蓉 | A kind of Chinese medicine preparation of chronic heart failure and preparation method thereof |
| CN108478704A (en) * | 2018-06-28 | 2018-09-04 | 习水县中医院 | Heart spleen giving young employees remedial-courses in general knowledge and vocational skills Chinese medicine composition and preparation method thereof |
-
2014
- 2014-12-11 CN CN201410765500.4A patent/CN105726931A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104587173A (en) * | 2014-12-26 | 2015-05-06 | 青岛市市立医院 | Traditional Chinese medicine preparation for treating chronic heart failure, as well preparation method thereof |
| CN106880826A (en) * | 2017-03-15 | 2017-06-23 | 付蓉 | A kind of Chinese medicine preparation of chronic heart failure and preparation method thereof |
| CN108478704A (en) * | 2018-06-28 | 2018-09-04 | 习水县中医院 | Heart spleen giving young employees remedial-courses in general knowledge and vocational skills Chinese medicine composition and preparation method thereof |
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