CN105726103B - A kind of uterine neck pore prevents adhesion device - Google Patents

A kind of uterine neck pore prevents adhesion device Download PDF

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Publication number
CN105726103B
CN105726103B CN201610084131.1A CN201610084131A CN105726103B CN 105726103 B CN105726103 B CN 105726103B CN 201610084131 A CN201610084131 A CN 201610084131A CN 105726103 B CN105726103 B CN 105726103B
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China
Prior art keywords
pipeline
uterine neck
support arm
prevents adhesion
hole
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CN105726103A (en
Inventor
吴小华
李璡
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Fudan University Shanghai Cancer Center
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Fudan University Shanghai Cancer Center
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Priority to CN201610084131.1A priority Critical patent/CN105726103B/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/42Gynaecological or obstetrical instruments or methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/42Gynaecological or obstetrical instruments or methods
    • A61B2017/4216Operations on uterus, e.g. endometrium
    • A61B2017/4225Cervix uteri

Abstract

The invention belongs to medical instruments fields, it discloses a kind of uterine neck pore to prevent adhesion device, includes the pipeline with hollow cavity, the end-enclosed of pipeline one end, pipeline is reserved at least two through-holes being connected to cavity on the side wall of blind end, and the two through-holes mutually deviate from the side wall of pipeline.The uterine neck pore device that prevents adhesion further includes defaulting in pipeline and support arm identical with the quantity of through-hole, these support arms and through-hole one-to-one correspondence and support arm can be stretched out from corresponding through-hole.The uterine neck pore of the present invention prevents adhesion device suitable for being placed in patient uterine during cervicectomy, can prevent the generation of the narrow adhesion in cervical canal hole after cervicectomy, can effectively reduce postoperative complications, improve patient's postoperative life quality.

Description

A kind of uterine neck pore prevents adhesion device
Technical field
The invention belongs to the field of medical instrument technology, more particularly to a kind of merging for being used in cervicectomy Equipment.
Background technology
Currently, cervical carcinoma is still the underlying cause of death of global patients with gynecologic malignancies, on the one hand, cervical carcinoma screening makes morning Phase cervical carcinoma makes a definite diagnosis ratio rising;On the other hand, as rejuvenation trend and modern society is presented in the cervical cancer pathogenesis age Childbearing age postpones, and in human invasive cervix neoplasms patient, the Proportion of patients that do not give birth to rises year by year.The tradition of human invasive cervix neoplasms Therapeutic modality is operation excision uterus and regional lymph nodes, or kills primary tumor and lymphatic drainage area tumour by radiotherapy, but Operation or radiotherapy will all cause patient to lose reproductive function while treating tumour.Factors above makes the fertility for retaining patient Function is more and more important in the treatment of cervical carcinoma.Charles Robert Richet Daniel Dargent carried out radical-ability for the first time in 1987 Cervicectomy (radical trachelectomy, RT).The excision extension of the art formula is similar to classical female radical cure temper Palace resection only cuts off the uterine neck of lesion, isthmus uteri and vagina upper end is coincide so that patient protects while curing tumour Reproductive function is stayed.RT operations at present mainly have female Radical trachelectomy (vaginal radical Trachelectomy, VRT) and abdomen formula Radical trachelectomy (abdominal radical trachelectomy, ART) Two kinds.
The narrow adhesion of uterine neck pore is postoperative complications the most typical and common after abdomen formula Radical trachelectomy, no But can influence the normal form in uterus and function so that influence human endocrine, and can cause it is infertile, this be clearly and ART What the original intention of operation reservation patient's reproductive function was disagreed.Receive the postoperative patients that the narrow adhesion of uterine neck pore occurs of ART often Have to receive again cervical canal bore expansion operation more than once, this undoubtedly to the body of sufferer, at heart and economy is born On all produce new pressure.
It is entitled application No. is CN201420660489.0《Uterine neck pore prevents adhesion device》Patent in, attempt to pass through The mode of T shape frame members is placed in art to prevent the narrow adhesion of uterine neck pore.However it was found by the inventors of the present invention that due to T The shape of shape frame member limits so that the uterine neck pore prevents adhesion device when being placed in intrauterine and being taken out from intrauterine, and transverse arm is not It can avoid ground to rub with patient's vagina and the interior of uterus, hinder operation, and patient may be scratched.
Invention content
It prevents adhesion device, is suitable for during cervicectomy it is an object of the present invention to provide a kind of uterine neck pore Be placed in patient uterine in, the generation of the narrow adhesion in cervical canal hole after cervicectomy can be prevented, can effectively reduce postoperative complications, Improve patient's postoperative life quality.
It prevents adhesion device, including tool in order to solve the above technical problems, embodiments of the present invention provide a kind of uterine neck pore There are the pipeline of hollow cavity, the end-enclosed of pipeline one end, pipeline to be reserved at least two and chamber on the side wall of blind end The through-hole of body connection, and the two through-holes mutually deviate from the side wall of pipeline.The uterine neck pore device that prevents adhesion further includes defaulting in In pipeline and support arm identical with the quantity of through-hole, these support arms and through-hole one-to-one correspondence and support arm can be from right therewith It is stretched out in the through-hole answered.
The uterine neck pore that embodiments of the present invention are provided prevents adhesion device, for during cervicectomy, suture Before stump palace body and vagina, after implementer carries out firm clamping using surgical instrument to pipeline, it is deeply placed into trouble Person's intrauterine.Then surgical instrument releases clamping, and support arm is stretched out from through-hole.The uterine neck pore prevent adhesion device merging patient Intrauterine, after patient sutures stump palace body and vagina, can the uterine neck pore caused by postoperative neck tube mucous membrane adhesion it is narrow have it is pre- Anti- effect;On the other hand, received the patient of cervicectomy after past adhesion acute stage, the cervical canal can be directly taken out The anti-sticking connected device in hole further takes out the uterine neck pore after can also withdrawing support arm in pipeline from through-hole and prevents adhesion device.
In terms of existing technologies, the uterine neck pore of the invention device that prevents adhesion effectively prevents patient palace occurs after surgery The complication of the narrow adhesion in neck tube hole, remains the reproductive function of patient, for improving the postoperative life matter of cervical cancer patient Amount and mental emotion state all have very great help.And embodiments of the present invention by support arm by being preset in hollow pipeline It is interior so that actually use the uterine neck pore prevent adhesion device when, which can be more successfully placed in patient uterine by operator It is interior, and prevent from scratching patient, and then alleviate the pain of patient.
Preferably, support arm is also hollow, the outer wall of support arm is tightly connected with the duct wall for constituting through-hole, support Arm can stretch out under the pressure that fluid is given from through-hole.Support arm is stretched out using Fluid pressure, it is mechanical relative to utilizing For transmission, the movement of support arm is softer, therefore can improve uterine neck pore and prevent adhesion the comfort of device, and preferably anti- Only to the issuable scratch of patient.
Further, preferably, pipeline one end opposite with blind end is equipped with closed opening, opening is with to pipeline In be filled with fluid.Closed opening is set so that fluid can fill repeatedly according to demand, and the fluid being filled with can be enabled to pipe Road forms support so that the amount of fluid can be filled with by control come the pliability of the quantitative control anti-sticking connected device in cervical canal hole.
In addition, preferably, be additionally provided with the sensor for detecting Fluid pressure in pipeline, wherein:
Sensor is connected with exterior terminal wireless communication.Alternatively, being additionally provided with alarm in pipeline, sensor is logical with alarm Letter connection.Fluid pressure sensor is set in pipeline, Fluid pressure can be monitored in real time, prevent fluid from overcharging.In addition, may be used also Amount with the fluid being filled with come quantitative control by sensor.
In embodiments of the present invention, fluid can be liquid or gas.When the fluid is gas, pipeline can be Sealing, generating agent is also preinstalled in pipeline, generating agent can generate gas, and gas expansion simultaneously drives support arm to be stretched from through-hole Go out.By controlling the amount of the substance of generating agent, the quantitative control to gas caused by generating agent may be implemented.And by generating agent It is pre- that for the mode for being filled with fluid, it is not necessary that opening is arranged, manufacture craft is simpler in the pipeline of sealing, at This control is more prone to, additionally it is possible to fluid be effectively prevent to be revealed from opening.
Further, preferably, the boiling point of generating agent is less than 37 degree, uterine neck pore prevents adhesion device when entering in human body, Since body temperature influences, generating agent gasifies and generates gas, and gas push support arm is stretched out from corresponding through-hole.Make To be preferred, generating agent can be carbon dioxide, CFC-11 (fluoro trichloromethane), HCFC-141b (1,1- bis- chloro- 1- fluoroethanes) Or HFC-245fa (1,1,1,3,3-pentafluoropropane).Wherein carbon dioxide has nontoxic characteristic, when dosage is smaller It is very suitable for using as generating agent, but frostbite may be caused when dosage is larger.And CFC-11 (fluoro trichloromethane), The boiling points near room temperature of HCFC-141b (1,1- bis- chloro- 1- fluoroethanes) and HFC-245fa (1,1,1,3,3-pentafluoropropane), more It is suitble to use as generating agent when dosage is larger.
Further, preferably, being also preinstalled with triggering agent in pipeline, trigger between agent and generating agent by film every From.When film breaks, triggers agent and generating agent is mutually mixed and generates gas.Using triggering agent and the chemical reaction of generating agent come When generating gas, generating agent is stored without low temperature, uterine neck pore is reduced and prevents adhesion the preservation cost of device.More further, Preferably, generating agent is hydrogen peroxide, triggering agent is manganese dioxide.Since hydrogen peroxide and manganese dioxide are swift in response, production Raw oxygen has no toxic side effect, and is ideal reaction material.
In addition, preferably, the lateral wall of support arm is equipped with for preventing the convex eaves in support arm retraction pipeline.Pass through Convex eaves can prevent support arm from retracting after manifold pressure reduction, improve uterine neck pore and prevent adhesion the stability of device.
Description of the drawings
Fig. 1 is that the uterine neck pore that first embodiment of the invention is provided prevents adhesion the signal of the support arm of device when not extending out Figure;
Fig. 2 be the uterine neck pore that first embodiment of the invention is provided prevent adhesion device support arm stretch out when signal Figure;
Fig. 3 is that the uterine neck pore that third embodiment of the invention is provided prevents adhesion the schematic diagram of device.
Reference sign:
1, pipeline;2, support arm, 3, convex eaves;4, film.
Specific implementation mode
To make the object, technical solutions and advantages of the present invention clearer, below in conjunction with attached drawing to each reality of the present invention The mode of applying is explained in detail.However, it will be understood by those skilled in the art that in each embodiment of the present invention, In order to make the reader understand this application better, many technical details are proposed.But even if without these technical details and base In the various changes and modifications of following embodiment, each claim of the application technical side claimed can also be realized Case.
Embodiment 1
Prevent adhesion device the first embodiment of the present invention is related to a kind of uterine neck pore, referring to Fig. 1 and Fig. 2 shown in, including tool Have a pipeline 1 of hollow cavity, the end-enclosed of 1 one end of pipeline, pipeline 1 be reserved on the side wall of blind end at least two with The through-hole of cavity connection, and the two through-holes mutually deviate from the side wall of pipeline 1.The uterine neck pore device that prevents adhesion further includes presetting In pipeline 1 and support arm 2 identical with the quantity of through-hole, these support arms 2 are corresponded with through-hole.Also, these are supported Arm 2 is also hollow, and the outer wall of support arm 2 is tightly connected with 1 wall of pipeline for constituting through-hole, and support arm 2 can be given in fluid Pressure under stretched out from corresponding through-hole.Support arm 2 is stretched out using Fluid pressure, for utilizing machine driving, The movement of support arm 2 is softer, therefore can improve uterine neck pore and prevent adhesion the comfort of device, and is better protected to patient Issuable scratch.Wherein, fluid can be liquid or gas.
The one end opposite with blind end of pipeline 1 is equipped with closed opening, and opening is filled with fluid with into pipeline 1.Setting Closed opening so that fluid can fill repeatedly according to demand, and the fluid being filled with can be enabled to form pipeline 1 and supported, from And the amount of fluid is filled with come the pliability of the quantitative control anti-sticking connected device in cervical canal hole by control.It is of course also possible to be not provided with out Mouthful, and pipeline 1 is filled using syringe or other analogs.Its shortcoming is that being unfolded in support arm 2, filling purpose reaches Needed after be discharged fluid, cause fluid can not structure twin conduit 1 and support arm 2 support, it is therefore desirable to pipeline 1 and support arm 2 need to select the better material of toughness.But this has no effect on the realization of basic fundamental purpose of the present invention.
Furthermore, it is understood that check valve can be arranged in opening, to prevent the fluid countercurrent current being filled with.
In addition, 2 retraction pipeline 1 of support arm in order to prevent, convex eaves 3 is also provided on the lateral wall of support arm 2.By convex Eaves 3 can prevent support arm 2 from retracting after pressure reduces in pipeline 1, improve uterine neck pore and prevent adhesion the stability of device.When So, when provided with opening, since the fluid being filled with can form support to support arm 2, convex eaves can not also be set 3, to reduce production cost.
In the present embodiment, the sensor (not illustrating in figure) for detecting Fluid pressure is additionally provided in pipeline 1, In, sensor is connected with exterior terminal wireless communication.Alternatively, alarm is additionally provided in pipeline 1, sensor and alarm communication link It connects.Fluid pressure sensor is set in pipeline 1, Fluid pressure can be monitored in real time, prevent fluid from overcharging.Further, it is also possible to Pass through the amount for the fluid that sensor is filled with come quantitative control.
The uterine neck pore that embodiments of the present invention are provided prevents adhesion device, for during cervicectomy, suture Before stump palace body and vagina, after implementer carries out firm clamping using surgical instrument to pipeline 1, it is deeply placed into trouble Person's intrauterine.Then surgical instrument releases clamping, is filled with fluid into pipeline 1 so that support arm 2 is stretched out from through-hole.Adjustment The plasticity and flexibility of the amount of fluid device outer wall so that uterine neck pore prevents adhesion are in the more comfortable interval range of patient It is interior, you can closing opening.The uterine neck pore prevents adhesion in device merging patient uterine, after patient sutures stump palace body and vagina, energy Uterine neck pore is narrow enough caused by postoperative neck tube mucous membrane adhesion prevention effect;On the other hand, receive the trouble of cervicectomy Person adhesion acute stage in the past after, the uterine neck pore can be directly taken out prevent adhesion device, can also be by being evacuated to pipeline 1 Mode further takes out the uterine neck pore after withdrawing support arm 2 in pipeline 1 from through-hole and prevents adhesion device.It in practical applications, can be with As revealed in the prior art, tailfiber is connected in the tail end of pipeline 1, and takes out the uterine neck pore using tailfiber and prevents adhesion device.
It is of course also possible to enable support arm 2 be stretched out from corresponding through-hole using machine driving or other modes.It is based on The various modifications for the basic ideas that present embodiment is provided, it should also be included within protection scope of the present invention.
In terms of existing technologies, the uterine neck pore of the invention device that prevents adhesion effectively prevents patient palace occurs after surgery The complication of the narrow adhesion in neck tube hole, remains the reproductive function of patient, for improving the postoperative life matter of cervical cancer patient Amount and mental emotion state all have very great help.And embodiments of the present invention by support arm 2 by being preset in hollow pipeline 1 It is interior so that actually use the uterine neck pore prevent adhesion device when, which can be more successfully placed in patient uterine by operator It is interior, and prevent from scratching patient, and then alleviate the pain of patient.
Embodiment 2
Second embodiment of the present invention is related to a kind of uterine neck pore and prevents adhesion device, second embodiment and the first embodiment party Formula is different, is in place of main difference, in the first embodiment of the present invention, the one end opposite with blind end of pipeline 1 Equipped with closed opening, and fluid can be liquid or gas;And in second embodiment of the present invention, which is gas Body, pipeline 1 are then sealings.
Specifically, generating agent is also preinstalled in pipeline 1, generating agent can generate gas, and gas expansion simultaneously drives support Arm 2 is stretched out from through-hole.By controlling the amount of the substance of generating agent, the quantitative to gas caused by generating agent may be implemented System.And generating agent is mounted in advance in the pipeline 1 of sealing, for the mode for being filled with fluid, it is not necessary that opening is arranged, make work Skill is simpler, and cost control is more prone to, additionally it is possible to fluid be effectively prevent to be revealed from opening.
In the present embodiment, the boiling point of generating agent is less than 37 degree, and uterine neck pore prevents adhesion device when entering in human body, due to Body temperature influences, and generating agent gasifies and generates gas, and gas push support arm 2 is stretched out from corresponding through-hole.It is theoretical For upper, as long as the boiling point of generating agent is less than 37 degree, so that it may to generate gas by gasifying or distilling, and provide support arm 2 Motive force.And frostbite, generating agent boiling point are advisable with approaching room temperature in order to prevent.
Specifically, generating agent can be carbon dioxide, CFC-11 (fluoro trichloromethane), HCFC-141b (1,1- bis- Chloro- 1- fluoroethanes) or HFC-245fa (1,1,1,3,3-pentafluoropropane).Wherein carbon dioxide has nontoxic characteristic, It is very suitable for when dosage is smaller as generating agent using, but frostbite may be caused when dosage is larger.And with CFC-11, The boiling points near room temperature of HCFC-141b and HFC-245fa is more suitable for using as generating agent when dosage is larger, wherein HCFC-141b toxicity is extremely low, and HFC-245fa then hardly has toxicity, therefore more safe and reliable when in use.
Finally, need to take out the uterine neck pore prevent adhesion device when, the table for the device that prevents adhesion in the uterine neck pore can be passed through Internal gas is expelled directly out (when non-toxic) by the mode of face trepanning, or (when having hypotoxicity) is discharged by Line Safety, then By have been drained off after gas it is flat under the uterine neck pore device that prevents adhesion take out.It has not been deposited in device since uterine neck pore at this time prevents adhesion In gas, so the process taken out is simpler, to the injury of patient also smaller.
Embodiment 3
Third embodiment of the present invention is related to a kind of uterine neck pore and prevents adhesion device, and third embodiment is the second embodiment party Being further improved for formula, mainly thes improvement is that, in third embodiment of the present invention, triggering is also preinstalled in pipeline 1 Agent triggers and is isolated by film 4 between agent and generating agent.
When film 4 ruptures, triggers agent and generating agent is mutually mixed and generates gas.That is, being placed in the uterine neck After the anti-sticking connected device of pore, film 4 can be made to rupture by way of applying external force, mutually be mixed to promote to trigger agent and generating agent It closes.
Using triggering agent and the chemical reaction of generating agent when generating gas, generating agent is stored without low temperature, reduces palace The preservation cost of the anti-sticking connected device in neck tube hole.More further, preferably, generating agent is hydrogen peroxide, triggering agent is dioxy Change manganese.Since hydrogen peroxide and manganese dioxide are swift in response, the oxygen of generation has no toxic side effect, and is ideal reaction material.When So, other reactants are selected, can also realize the goal of the invention of the present invention substantially.
It will be understood by those skilled in the art that the respective embodiments described above are to realize specific embodiments of the present invention, And in practical applications, can to it, various changes can be made in the form and details, without departing from the spirit and scope of the present invention.

Claims (9)

  1. The device 1. a kind of uterine neck pore prevents adhesion, which is characterized in that include the pipeline with hollow cavity, the end of described pipeline one end Portion closes, and the pipeline is reserved at least two through-holes being connected to the cavity, and this on the side wall of the blind end Two through-holes mutually deviate from the side wall of the pipeline;
    The uterine neck pore device that prevents adhesion further includes defaulting in the pipeline and support arm identical with the quantity of the through-hole, These support arms are corresponded with through-hole and the support arm can be stretched out from corresponding through-hole;
    Wherein, the support arm is also hollow, and the outer wall of the support arm is tightly connected with the duct wall for constituting the through-hole, The support arm can stretch out under the pressure that fluid is given from the through-hole.
  2. The device 2. uterine neck pore according to claim 1 prevents adhesion, it is characterised in that:The pipeline is opposite with the blind end One end be equipped with closed opening, the opening with into the pipeline is filled with fluid.
  3. The device 3. uterine neck pore according to claim 1 prevents adhesion, it is characterised in that:It is additionally provided in the pipeline for detecting The sensor of Fluid pressure, wherein:
    The sensor is connected with exterior terminal wireless communication;
    Alternatively, being additionally provided with alarm in the pipeline, the sensor is communicated to connect with the alarm.
  4. The device 4. uterine neck pore according to claim 1 prevents adhesion, it is characterised in that:The fluid is gas, the pipeline It is sealing, generating agent is also preinstalled in the pipeline, the generating agent can generates the gas, the gas expansion and band The support arm is moved to stretch out from the through-hole.
  5. The device 5. uterine neck pore according to claim 4 prevents adhesion, it is characterised in that:The boiling point of the generating agent is less than 37 Degree, uterine neck pore prevent adhesion device when entering in human body, and the generating agent gasifies and generates the gas.
  6. The device 6. uterine neck pore according to claim 5 prevents adhesion, it is characterised in that:The generating agent be carbon dioxide, CFC-11, HCFC-141b or HFC-245fa.
  7. The device 7. uterine neck pore according to claim 4 prevents adhesion, it is characterised in that:Triggering is also preinstalled in the pipeline Agent is isolated between the triggering agent and the generating agent by film;
    When the film breaks, the triggering agent and the generating agent are mutually mixed and generate the gas.
  8. The device 8. uterine neck pore according to claim 7 prevents adhesion, it is characterised in that:The generating agent is hydrogen peroxide, institute It is manganese dioxide to state triggering agent.
  9. The device 9. uterine neck pore according to claim 1 prevents adhesion, it is characterised in that:The lateral wall of the support arm is equipped with For preventing the support arm from retracting the convex eaves in the pipeline.
CN201610084131.1A 2016-02-05 2016-02-05 A kind of uterine neck pore prevents adhesion device Active CN105726103B (en)

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US4578076A (en) * 1984-03-20 1986-03-25 The Population Council, Inc. Medicated intracervical and intrauterine devices
EP0117163B1 (en) * 1983-01-07 1987-08-19 Marc Levrier Contraceptive and therapeutic introuterine device combining copper, natural progesterone and amino-iso caproic acid
CN1151686A (en) * 1994-07-05 1997-06-11 莱拉斯股份公司 Device for the release of an active agent
CN1741776A (en) * 2002-02-12 2006-03-01 迪尔克·维尔德梅尔施 T-shaped intra-uterine device and method for the production thereof
CN104323829A (en) * 2014-11-06 2015-02-04 复旦大学附属肿瘤医院 Cervical canal hole anti-sticking device and application thereof
CN104771210A (en) * 2014-01-10 2015-07-15 凌安东 Foldable automatic replica isolating membrane for preventing metrosynizesis
CN205514823U (en) * 2016-02-05 2016-08-31 复旦大学附属肿瘤医院 Cervical canals hole anti -adhesion device

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US8048086B2 (en) * 2004-02-25 2011-11-01 Femasys Inc. Methods and devices for conduit occlusion
CN104661622B (en) * 2012-08-09 2016-11-16 米斯拉制药公司 Intrauterine device

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0117163B1 (en) * 1983-01-07 1987-08-19 Marc Levrier Contraceptive and therapeutic introuterine device combining copper, natural progesterone and amino-iso caproic acid
US4578076A (en) * 1984-03-20 1986-03-25 The Population Council, Inc. Medicated intracervical and intrauterine devices
CN1151686A (en) * 1994-07-05 1997-06-11 莱拉斯股份公司 Device for the release of an active agent
CN1741776A (en) * 2002-02-12 2006-03-01 迪尔克·维尔德梅尔施 T-shaped intra-uterine device and method for the production thereof
CN104771210A (en) * 2014-01-10 2015-07-15 凌安东 Foldable automatic replica isolating membrane for preventing metrosynizesis
CN104323829A (en) * 2014-11-06 2015-02-04 复旦大学附属肿瘤医院 Cervical canal hole anti-sticking device and application thereof
CN205514823U (en) * 2016-02-05 2016-08-31 复旦大学附属肿瘤医院 Cervical canals hole anti -adhesion device

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