CN105688332A

CN105688332A - Portable CES therapeutic instrument stimulator

Info

Publication number: CN105688332A
Application number: CN201410672723.6A
Authority: CN
Inventors: 李晓波
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-11-23
Filing date: 2014-11-23
Publication date: 2016-06-22

Abstract

The invention discloses a portable CES therapeutic instrument stimulator, which can output needed therapeutic waveforms and operate stably and reliably, and has the advantages of low power consumption, portability, miniature and strong interactivity. A new therapeutic device is provided for rehabilitation and health care of a patient and psychiatric treatment. The portable CES therapeutic instrument stimulator comprises a main control chip module and a power module, and is structurally characterized in that one input port of the main control chip is connected with a key input module; one output port of the main control chip is connected with an LCD display module; the other output port of the main control chip is connected with a digital-to-analog conversion circuit module; the output end of the digital-to-analog conversion module is connected with a constant current source circuit module; the output end of the constant current source circuit module is connected with an output electrode module; and output of the power module is provided for the main control chip, the digital-to-analog conversion circuit module, the constant current source circuit module and the output electrode module.

Description

A kind of stimulator of portable CES therapeutic instrument

Technical field

The invention belongs to medical electronics field, particularly the stimulator of a kind of portable CES therapeutic instrument。

Background technology

Through the electromedicine method that cranium microelectric current therapy (CES) is the mental sickness such as treatment depression, anxiety, insomnia。The countries such as this therapy has had years development history abroad, present America and Europe have been commonly used, are approved as an effective Therapeutic Method of maturation by Bureau of Drugs Supervision of the U.S. (FDA)。Introduce China from the approval through state food and drug administration in 2002, have wide use in clinics such as China's psychiatric department, Psychology Dept. and rehabilitation departments。

This therapy ultimate principle is by being clipped in the ear-clip electrodes of ear-lobe generation low-intensity micro-current stimulation brain, change the brain wave that brain in patients is abnormal, promoting brain secretion a series of with anxiety, depression, insomnia etc. there is neurotransmitter and the hormone of close ties in disease, to realize the treatment to these diseases。Alpha-stim ripple is a kind of typical waveform adopting CES therapy, it is a kind of improvement square wave, have two-way waveform, per second send 0.5 pulse, 10 to 500/1000000ths amperes, blahs aypnia anxiety etc. is produced desirable curative effect by it, the effectiveness study of a microelectric current instrument adopting Alpha-stim waveform has been analyzed by HSPH of Harvard University: the effective percentage to insomnia is 79.62%, effective percentage for anxiety neurosis is 93.70%, and the effective percentage for depression is 89.67%。

China's various big hospital it has been applied at present through the micro-electric current therapy of cranium, mostly the research being seen in domestic periodical is the medical statistics of curative effect, the correlation technique article of system development in this respect is extremely rare, normally only give side circuit design, but its scheme also not produces complete Alpha-stim waveform。

Summary of the invention

The present invention is aiming at different patient and adopts different stimulated intensity, shows treatment time and battery electric quantity, it is provided that the stimulator of a kind of portable CES therapeutic instrument simultaneously；The present invention can export required treatment waveform and stable and reliable operation。There is low-power consumption, portable, miniaturization, the strong feature of interactivity。Rehabilitation and mental sickness treatment for patient provide a kind of new therapeutic equipment。

For realizing the above-mentioned purpose of the present invention, the present invention adopts the following technical scheme that。

The stimulator of a kind of portable CES therapeutic instrument of the present invention, including main control chip module, power module, its structural feature is: an input port of described main control chip connects keyboard input module；One output port of described main control chip connects LCD display module, another output port of described main control chip connects D/A converting circuit module, the outfan of described D/A converter module connects constant-current source circuit module, and the outfan of described constant-current source circuit module connects output electricity level module；The output of described power module is supplied respectively to main control chip, D/A converting circuit module, constant-current source circuit module, output electrode module。

As a preferred embodiment of the present invention, described main control chip module adopts STM32F103C8T6 single-chip microcomputer；This chip is based on the RISC kernel of ARMCortex-M332 position, internal high-speed memories (flash memory of 64KB and the SRAM of 20KB)。

As the another kind of preferred version of the present invention, described D/A converter module adopts AD5452 serial D/A transducer；Described AD5452 is 12 figure place weighted-voltage D/A converters, adopts 3-line serial interface with main control chip module。

As the another kind of preferred version of the present invention, described LCD display module adopts the PCD8544 LCD controller of PHILIPS company；Described constant-current source circuit module adopts bipolarity precision constant current source circuit；Described bipolarity precision constant current source circuit is made up of two precision operational-amplifiers。

The invention has the beneficial effects as follows。

1, the invention provides the stimulator of a kind of portable CES therapeutic instrument, it is designed with the stimulator through cranium microelectric current therapy based on STM32F103C8T6 microcomputer development, instrument adopts STM32 to produce electric pulse, converts through D/A and controls the micro-electric current of bipolarity that constant current circuit for generating produces to meet needed for cranium microelectric current therapy for treating。This stimulator adopts different stimulated intensity for different patients, shows treatment time and battery electric quantity simultaneously。This instrument can pass through to produce bipolarity, and asymmetrical square wave provides through cranium microelectric current, and output waveform frequency is 0.5Hz, and current intensity is continuously adjustabe between 10 μ A-500 μ A, has good stability and reliability。

2, being a kind of safe and harmless non-drug therapy treating the mental sickness such as depressive anxiety insomnia through cranium microelectric current therapy, range of application will be more and more wider。This microelectric current instrument of the present invention can export required treatment waveform and stable and reliable operation；There is low-power consumption, portable, miniaturization, the strong feature of interactivity。Rehabilitation and mental sickness treatment for patient provide a kind of new therapeutic equipment。

Accompanying drawing explanation

Fig. 1 is the overall structure block diagram of the stimulator of a kind of portable CES therapeutic instrument of the present invention。

Fig. 2 is the D/A converting circuit connection figure of the stimulator of a kind of portable CES therapeutic instrument of the present invention。

Fig. 3 is the bipolarity precision constant current source circuit connection diagram of the stimulator of a kind of portable CES therapeutic instrument of the present invention。

Detailed description of the invention

As it is shown in figure 1, be the overall structure block diagram of the stimulator of a kind of portable CES therapeutic instrument of the present invention。In figure, including main control chip module, power module, its structural feature is: an input port of described main control chip connects keyboard input module；One output port of described main control chip connects LCD display module, another output port of described main control chip connects D/A converting circuit module, the outfan of described D/A converter module connects constant-current source circuit module, and the outfan of described constant-current source circuit module connects output electricity level module；The output of described power module is supplied respectively to main control chip, D/A converting circuit module, constant-current source circuit module, output electrode module。

The present invention adopts periodic bipolar constant current output, and output electric current is not by the impact of human body resistance change, it is ensured that therapeutic effect。It is simultaneous for different patient, scalable output current intensity and optional treatment time, reaches optimum therapeuticing effect。System adopts mcu programming to produce a required voltage waveform, this voltage waveform signal is become analogue signal by D-A converting circuit, deliver to bipolarity precision constant current source circuit, control the size of current of constant-current source circuit, obtain the electric current output of periodic bipolar through constant-current source circuit。

Described main control chip module adopts STM32F103C8T6 single-chip microcomputer, this chip is based on the RISC kernel of ARMCortex-M332 position, it is up to the operating frequency of 72MHz, internal high-speed memories (flash memory of 64KB and the SRAM of 20KB), possesses abundant strengthening I/O port and be connected to the peripheral hardware of two APB buses。The Timer/Counter of three 16 is had, it is possible to meet native system and working time, pulsewidth, the accurate of pulse frequency are controlled in STM32F103C8T6 single-chip microcomputer。Additionally single-chip microcomputer also has 2 12 ADC, it is possible to for the collection of the stimulus intensity of conditioning instrumentation and battery electric quantity signal。Independent hardware watchdog clock is had, it is possible to be effectively prevented single chip microcomputer halt inside STM32F103C8T6 single-chip microcomputer。

Described LCD display module adopts the PCD8544 LCD controller of PHILIPS company；The CMOSLCD that this LCD controller is one piece of low-power consumption controls driver, and the figure that can realize 48 row 84 row shows。Owing to its necessary display function is integrated on one chip, including LCD voltage and bias voltage generator, therefore a small amount of outer member of only need to arranging in pairs or groups can realize display and circuit power consumption is little。Main control chip module is mainly used to control liquid crystal display, the setting for the treatment of time, the adjustment etc. for the treatment of current intensity；It addition, it produces a periodically pulsing signal, control the constant current output in main circuit。

Described D/A converter module is responsible for the digital quantity of single-chip microcomputer output to convert ambipolar voltage to, gives bipolar precision constant current source circuit, thus realizing the control that constant-current source electric current is exported by single-chip microcomputer；The bipolar output voltage circuit that this part is made up of peripheral amplifier and the resistance of D/A conversion chip and some necessity。

As in figure 2 it is shown, be the D/A converting circuit connection figure of the stimulator of a kind of portable CES therapeutic instrument of the present invention。In figure, circuit connection structure is: the GND port of described AD5452 connects the positive pole of U1A, and the IOUT1 port of described AD5452 connects the negative pole of U1A；The RFB port of described AD5452 connects resistance R3, and resistance R3 is connected with the outfan of U1A again；The outfan of described U1A is also connected with resistance R5, and resistance R5 connects the negative pole of U1B again, and the positive pole of U1B is connected to the GND port of AD5452；The outfan of described U1B connects R4, R4 and electrically connects R2, R2 again and electrically connect R1, R1 again and be finally electrically connected to the VREF port of AD5452。The present invention considers that parallel D/A converter size is big, and pin is many, is unfavorable for miniaturized design, thus the present invention adopts AD5452 serial D/A transducer。AD5452 is 12 analog-digital converters, adopts 3-line serial interface with CPU。In order to need to produce bipolar voltage output in this circuit, the two-way amplifier that U1A, U1B represent some non-essential resistances of arranging in pairs or groups are utilized to realize；Amplifier U1A performs electric current and changes to voltage, and second amplifier U1B provides the gain of twice。

As it is shown on figure 3, be the bipolarity precision constant current source circuit connection diagram of the stimulator of a kind of portable CES therapeutic instrument of the present invention。In circuit diagram, connected to form by operational amplifier U1C and U1D, for obtaining high-precision output electric current in this circuit, reduce system power dissipation, operational amplifier selects TL064, the features such as it has high-gain, low drifting, the linearity is good, the high and low power consumption of resolution, input impedance high, capacity of resisting disturbance is strong, due to the positive negative output of needs, this amplifier adopts dual power supply。Operational amplifier U1C and U1D is operated in linear zone, and thinks that two amplifiers are ideal operational amplificr。Wherein U1C constitutes differential voltage amplifier, and U1D constitutes voltage follower。

It is understandable that, above with respect to the specific descriptions of the present invention, it is merely to illustrate the present invention and is not limited to the technical scheme described by the embodiment of the present invention, it will be understood by those within the art that, still the present invention can be modified or equivalent replacement, to reach identical technique effect；Needs are used, all within protection scope of the present invention as long as meeting。

Claims

1. a stimulator for portable CES therapeutic instrument, including main control chip module, power module；It is characterized in that: an input port of described main control chip connects keyboard input module；One output port of described main control chip connects LCD display module, another output port of described main control chip connects D/A converting circuit module, the outfan of described D/A converter module connects constant-current source circuit module, and the outfan of described constant-current source circuit module connects output electricity level module；The output of described power module is supplied respectively to main control chip, D/A converting circuit module, constant-current source circuit module, output electrode module。

2. the stimulator of a kind of portable CES therapeutic instrument according to claim 1, it is characterised in that: described main control chip module adopts STM32F103C8T6 single-chip microcomputer；This chip is based on the RISC kernel of ARMCortex-M332 position, internal high-speed memories (flash memory of 64KB and the SRAM of 20KB)。

3. the stimulator of a kind of portable CES therapeutic instrument according to claim 1, it is characterised in that: described D/A converter module adopts AD5452 serial D/A transducer；Described AD5452 is 12 figure place weighted-voltage D/A converters, adopts 3-line serial interface with main control chip module。

4. the stimulator of a kind of portable CES therapeutic instrument according to claim 1, it is characterised in that: described LCD display module adopts the PCD8544 LCD controller of PHILIPS company；Described constant-current source circuit module adopts bipolarity precision constant current source circuit；Described bipolarity precision constant current source circuit is made up of two precision operational-amplifiers。