CN105662859A - Laminating rubber plug and production method thereof - Google Patents
Laminating rubber plug and production method thereof Download PDFInfo
- Publication number
- CN105662859A CN105662859A CN201610194548.3A CN201610194548A CN105662859A CN 105662859 A CN105662859 A CN 105662859A CN 201610194548 A CN201610194548 A CN 201610194548A CN 105662859 A CN105662859 A CN 105662859A
- Authority
- CN
- China
- Prior art keywords
- plug
- laminated adhesive
- glue
- neck
- rubber plug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1475—Inlet or outlet ports
- A61J1/1487—Inlet or outlet ports with friction fit, e.g. connecting tubes directly to a protruding port
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D99/00—Subject matter not provided for in other groups of this subclass
- B29D99/0096—Producing closure members for containers, e.g. closure caps or stoppers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/56—Stoppers or lids for bottles, jars, or the like, e.g. closures
Abstract
The invention discloses a laminating rubber plug which comprises a rubber plug crown part and a rubber plug neck part, wherein the bottom surface of the rubber plug neck part is a spherical arc surface; the surface of the plug neck is covered with a film; the laminating part stretches from the surface of the plug neck to the plane position of the plug crown part sealed with a bottleneck; the plug column part of the rubber plug neck part has a small top and a big bottom; and spherical concave pinpricks are formed in the top surface of the rubber plug crown part, and protuberances are arranged around the pinpricks. The invention also discloses a production method of the laminating rubber plug, which comprises four steps of piece squeezing, piece punching, vulcanization and after-treatment. Due to the technical scheme, direct contact between the rubber plug and tablets can be prevented, the medicine is prevented from permeating and being precipitated and dissolved out for sure, the air tightness can be guaranteed, the plug jump can be avoided in automatic encapsulation, and exceeding fragmentation caused by a non-standard needle can be prevented; and moreover, secondary vulcanization is reduced in the production method, the silicification technology is not adopted, the materials and secondary pollution are reduced, and the original characteristics of the film materials are guaranteed.
Description
Technical field
The present invention relates to a kind of laminated adhesive plug and production method thereof, it is mainly used in the encapsulation sealing of injection medicine.
Technical background
The existing glue plug for the sealing of injection drug encapsulation when sealing medicine, if medicine is inverted, bottleneck there will be infiltration, precipitation affects the security of medicine; Liquid drugs injection medicine directly contacts with glue plug, can produce the material such as " infiltration ", " stripping ", " precipitation ", " leaching ", " can extract " and cause drug safety to reduce; The existing glue plug for the sealing of injection drug encapsulation, can cause fragmentation to exceed standard when the non-standard syringe needle of clinical middle use punctures; Existing glue plug production process is in order to ensure stability during high speed packing, it is necessary to glue is filled in row siliconizing, and medicine can be polluted by silicone oil, affects the security of medicine; Traditional medical rubber stopper production process needs twice sulfuration to cause environmental pollution.
Summary of the invention
In order to overcome the deficiencies in the prior art, the present invention seeks to open a kind of laminated adhesive plug and production method thereof, to solve existing glue plug, infiltration, precipitation, poorly sealed problem occur when encapsulating sealing injection; Injection medicine directly contacts with glue plug affects drug safety, the non-standard syringe needle fragmentation of Clinical practice exceeds standard affect drug safety, silicone oil medicine is polluted affect post cure in drug safety, production process cause environmental pollution problem.
To achieve the above object of the invention, the present invention provides following technical scheme:
Described a kind of laminated adhesive plug, comprise glue plug hat portion (1) and glue plug neck (2), it is characterized in that the bottom surface of described glue plug neck (2) is spherical circular arc face, glue plug neck (2) surface is covered with film (4), and overlay film position extends to plug hat position and the planimetric position of bottleneck sealing from glue plug neck (2) surface always.
Aforesaid a kind of laminated adhesive plug, described overlay film position extends to plug hat position and the plane 1/5th of bottleneck sealing from glue plug neck (2) surface always.
Aforesaid a kind of laminated adhesive plug, the plug portion (3) of described glue plug neck (2) is little above, below big.
Aforesaid a kind of laminated adhesive plug, the end face of described glue plug hat portion (1) is provided with spherical concave surface acupuncture hole (5).
Aforesaid a kind of laminated adhesive plug, the described end face at glue plug hat portion (1) is provided with symmetrical projection part (6).
Aforesaid a kind of laminated adhesive plug, described projection part (6) is the annulus around acupuncture hole (5).
The production method of aforesaid a kind of laminated adhesive plug, carries out according to following step:
Step one, crowded sheet
Adopt forcing machine that the sizing material mixed is extruded into sheet rubber;
Step 2, punching
Sheet rubber step one extruded is placed on film, pressing, then the sheet rubber that pressing has film is placed on punch die to be washed into blocks of circular overlay film rubber disk together;
Step 3, sulfuration
Circular overlay film rubber disk step 2 made is placed in the die cavity of mould, overlay film face under, and then above described circular overlay film rubber disk, put one layer of rubber according to glue plug weight, then carry out sulfuration, namely make laminated adhesive plug sheet;
Step 4, aftertreatment
Laminated adhesive plug sheet step 3 vulcanizated carries out die-cut, cleaning.
The present invention is owing to adopting technique scheme, and the overlay film position of laminated adhesive plug adopts spherical circular arc face design, guarantee film extension homogeneity, thickness homogeneity, shielding homogeneity to medicine, it is ensured that preparation security; The plug portion of laminated adhesive plug plug neck portion adopts little above, below big design prevent glue plug plug jumping in the process of continuous packing; The surface of glue plug neck is covered with film, overlay film position extends to the position of the plane 1/5th of plug hat position and bottleneck sealing from plug neck always, the combination at the design of overlay film and the position of overlay film, can realize that medicine can not permeate, precipitates out, stripping, make medication containment prevent medicine because poorly sealed generation potential safety hazard; It is arranged on the spherical concave surface acupuncture hole on glue plug surface, effectively reducing puncture force, prevent the fragmentation because using non-standard syringe needle to cause from exceeding standard, spherical concave design makes glue plug hat portion not stay right angle, dead angle, glue plug easy cleaning, convenient and safe when nurse sterilizes before using preparation; Taking the structure arranging projection on glue plug surface, make glue plug there will not be adhesion when high speed packing, ensure stability during high speed packing, outside acupuncture hole, the design of annulus projection, not only prevents glue plug adhesion, also helps suction steadily put when machine walked by glue plug fixed. Once shaped laminated adhesive plug is in process of production without the need to secondary high-temperature sulfuration, do not use silicification technics, do not use any chemical binder, without the secondary pollution of material, the physicals of sizing material and film is not any change, and product breaks without any, without any micropore, without any aging, it is ensured that film material primary characteristic.
Accompanying drawing explanation
Fig. 1 laminated adhesive plug vertical view;
Fig. 2 laminated adhesive plug cross section structure schematic diagram;
Fig. 3 laminated adhesive plug with packing bottle in conjunction with schematic cross-section;
Embodiment
Below in conjunction with accompanying drawing and embodiment, the technical scheme of the present invention is described in further detail:
Embodiment one: if Fig. 1 is laminated adhesive plug vertical view, Fig. 2 is laminated adhesive plug cross section structure schematic diagram, Fig. 3 be laminated adhesive plug with packing bottle in conjunction with shown in schematic cross-section, glue plug comprises glue plug hat portion (1) and glue plug neck (2), described glue plug neck (2) adopts spherical circular arc face to design, the plug portion (3) of glue plug neck (2) is little above, big below, glue stopper neck portion (2) bottom surface is spherical circular arc face, the overlay film position of laminated adhesive plug adopts spherical circular arc face to design, ensure film extension homogeneity, thickness homogeneity, to the shielding homogeneity of medicine, guarantee preparation security, plug jumping is stopped absolutely when plug portion (3) up-small and down-big design can ensure high speed packing again, improve stability, prevent the secondary pollution that plug jumping causes when packing,It is covered with film (4) on plug neck (2) surface, overlay film position extends to 1/5th of the planimetric position of plug hat position and bottleneck sealing from plug neck surface always, the design of overlay film and the position of overlay film extend to 1/5th places of the plane of plug hat position and bottleneck sealing, can not only prevent injection medicine from directly contacting with glue plug colloid, and can ensure that medicine also there will not be in inversion situation and ooze out precipitation, thus protect the security of medicine; The end face of described glue plug plug hat portion (1) is provided with spherical concave surface acupuncture hole (5), spherical female face is taked to design, reduce puncture force, when can effectively prevent from using non-standard syringe needle to puncture, fragmentation exceeds standard, spherical concave design makes glue plug hat portion not stay right angle, dead angle, glue plug easy cleaning, convenient and safe when nurse sterilizes before using preparation; Plane around acupuncture hole (5) is provided with symmetrical projection part (6), this kind of design is taked not only to eliminate the technique of silication, and ensure glue plug when packing without any resistance, also prevent the impact of silicone oil in silicatization process and the phenomenon that injection is defective occurs.
Embodiment two: as Fig. 1 to be laminated adhesive plug vertical view, Fig. 2 be laminated adhesive plug cross section structure schematic diagram, Fig. 3 be laminated adhesive plug with packing bottle in conjunction with shown in schematic cross-section, it is also possible at laminated adhesive plug ring cast-over acanthopore (5), annulus projection is set. Annulus projection, higher than glue plug plane, not only prevents glue plug adhesion, also helps suction steadily put when machine walked by glue plug fixed.
The production method of laminated adhesive plug of the present invention, step is as follows:
Step one, crowded sheet
Adopt forcing machine that the sizing material mixed is extruded into sheet rubber;
Step 2, punching
Sheet rubber step one extruded is placed on film, pressing, then the sheet rubber that pressing has film is placed on punch die to be washed into blocks of circular overlay film rubber disk together;
Step 3, sulfuration
Circular overlay film rubber disk step 2 made is placed in the die cavity of mould, overlay film face under, and then above described circular overlay film rubber disk, put one layer of rubber according to glue plug weight, then carry out sulfuration, namely make laminated adhesive plug sheet;
Step 4, aftertreatment
Laminated adhesive plug sheet step 3 vulcanizated carries out die-cut, cleaning.
The production method of above-mentioned once shaped laminated adhesive plug, in process of production without the need to secondary high-temperature sulfuration, do not use silicification technics, not using any chemical binder, the physicals without the secondary pollution of material, sizing material and film is not any change, product breaks without any, without any micropore, without any aging, it is ensured that film material primary characteristic.
In addition to the implementation, the present invention can also have other enforcement modes. All employings are equal to replacement or the technical scheme of equivalent transformation formation, all drop on the protection domain of requirement of the present invention.
Claims (7)
1. a laminated adhesive plug, comprise glue plug hat portion (1) and glue plug neck (2), it is characterized in that the bottom surface of described glue plug neck (2) is spherical circular arc face, glue plug neck (2) surface is covered with film (4), and overlay film position extends to plug hat position and the planimetric position of bottleneck sealing from glue plug neck (2) surface always.
2. a kind of laminated adhesive plug according to claim 1, it is characterised in that described overlay film position extends to plug hat position and the plane 1/5th of bottleneck sealing from glue plug neck (2) surface always.
3. a kind of laminated adhesive plug according to claim 1, it is characterised in that the plug portion (3) of described glue plug neck (2) is little above, below big.
4. a kind of laminated adhesive plug according to claim 1, it is characterised in that the end face of described glue plug hat portion (1) is provided with spherical concave surface acupuncture hole (5).
5. a kind of laminated adhesive plug according to claim 1, it is characterised in that the described end face at glue plug hat portion (1) is provided with symmetrical projection part (6).
6. a kind of laminated adhesive plug according to claim 1 and 5, it is characterised in that described projection part (6) is the annulus around acupuncture hole (5).
7. the production method of a kind of laminated adhesive plug according to claim 1, it is characterised in that carry out according to following step:
Step one, crowded sheet
Adopt forcing machine that the sizing material mixed is extruded into sheet rubber;
Step 2, punching
Sheet rubber step one extruded is placed on film, pressing, then the sheet rubber that pressing has film is placed on punch die to be washed into blocks of circular overlay film rubber disk together;
Step 3, sulfuration
Circular overlay film rubber disk step 2 made is placed in the die cavity of mould, overlay film face under, and then above described circular overlay film rubber disk, put one layer of rubber according to glue plug weight, then carry out sulfuration, namely make laminated adhesive plug sheet;
Step 4, aftertreatment
Laminated adhesive plug sheet step 3 vulcanizated carries out die-cut, cleaning.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610194548.3A CN105662859A (en) | 2016-03-29 | 2016-03-29 | Laminating rubber plug and production method thereof |
| PCT/CN2017/078409 WO2017167175A1 (en) | 2016-03-29 | 2017-03-28 | Membrane-coated rubber plug and method for producing same |
| JP2019600003U JP3222491U (en) | 2016-03-29 | 2017-03-28 | Film-coated rubber stopper |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610194548.3A CN105662859A (en) | 2016-03-29 | 2016-03-29 | Laminating rubber plug and production method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105662859A true CN105662859A (en) | 2016-06-15 |
Family
ID=56225569
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610194548.3A Pending CN105662859A (en) | 2016-03-29 | 2016-03-29 | Laminating rubber plug and production method thereof |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JP3222491U (en) |
| CN (1) | CN105662859A (en) |
| WO (1) | WO2017167175A1 (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106214483A (en) * | 2016-08-31 | 2016-12-14 | 上海太平洋实业有限公司 | A kind of arc steps double-colored composite cover of medical transfusion goods |
| WO2017167175A1 (en) * | 2016-03-29 | 2017-10-05 | 江苏华兰药用新材料股份有限公司 | Membrane-coated rubber plug and method for producing same |
| CN111568759A (en) * | 2019-09-05 | 2020-08-25 | 深圳艾欣达伟医药科技有限公司 | Packaging bottle for AST-3424 injection, packaging kit and method |
| CN112409710A (en) * | 2020-11-03 | 2021-02-26 | 山东省药用玻璃股份有限公司 | Freeze-drying film-coated butyl rubber plug and preparation method thereof |
| WO2021043275A1 (en) * | 2019-09-05 | 2021-03-11 | 深圳艾欣达伟医药科技有限公司 | Packaging bottle and packaging kit for injection, and filling, stoppering and capping device and method |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110623565B (en) * | 2019-09-27 | 2021-01-22 | 南通杰旺快餐有限公司 | Automatic locking protection device of thermos bottle plug of temperature measurement |
| CN113291607A (en) * | 2021-04-21 | 2021-08-24 | 安徽华峰医药橡胶有限公司 | Novel medical rubber plug |
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| JPS5747637A (en) * | 1980-09-06 | 1982-03-18 | Daikyo Gomme Seikou:Kk | Manufacture of laminate rubber stopper |
| CN200948238Y (en) * | 2006-08-25 | 2007-09-19 | 江阴兰陵瓶塞有限公司 | Laminated film rubber plug with sealed protruding tendon having taper angle ring shape |
| CN201192463Y (en) * | 2008-03-27 | 2009-02-11 | 江阴兰陵瓶塞有限公司 | Laminated glue plug |
| CN101973131A (en) * | 2010-09-13 | 2011-02-16 | 江苏华兰药用新材料股份有限公司 | Preparation method of filmed rubber stopper |
| CN102078257A (en) * | 2011-02-17 | 2011-06-01 | 江苏华兰药用新材料股份有限公司 | Coated rubber plug |
| CN204671572U (en) * | 2015-05-12 | 2015-09-30 | 江苏华兰药用新材料股份有限公司 | Remodeling coated rubber plug |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201192464Y (en) * | 2008-03-31 | 2009-02-11 | 江阴兰陵瓶塞有限公司 | Medical laminated glue plug |
| JP5553494B2 (en) * | 2008-09-02 | 2014-07-16 | 三笠産業株式会社 | Medical cap and method for manufacturing the same |
| CN103271822A (en) * | 2013-05-22 | 2013-09-04 | 盛州橡塑胶（苏州）有限公司 | Seamless laminated rubber plug and preparation method thereof |
| CN105662859A (en) * | 2016-03-29 | 2016-06-15 | 江苏华兰药用新材料股份有限公司 | Laminating rubber plug and production method thereof |
-
2016
- 2016-03-29 CN CN201610194548.3A patent/CN105662859A/en active Pending
-
2017
- 2017-03-28 JP JP2019600003U patent/JP3222491U/en active Active
- 2017-03-28 WO PCT/CN2017/078409 patent/WO2017167175A1/en active Application Filing
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5747637A (en) * | 1980-09-06 | 1982-03-18 | Daikyo Gomme Seikou:Kk | Manufacture of laminate rubber stopper |
| CN200948238Y (en) * | 2006-08-25 | 2007-09-19 | 江阴兰陵瓶塞有限公司 | Laminated film rubber plug with sealed protruding tendon having taper angle ring shape |
| CN201192463Y (en) * | 2008-03-27 | 2009-02-11 | 江阴兰陵瓶塞有限公司 | Laminated glue plug |
| CN101973131A (en) * | 2010-09-13 | 2011-02-16 | 江苏华兰药用新材料股份有限公司 | Preparation method of filmed rubber stopper |
| CN102078257A (en) * | 2011-02-17 | 2011-06-01 | 江苏华兰药用新材料股份有限公司 | Coated rubber plug |
| CN204671572U (en) * | 2015-05-12 | 2015-09-30 | 江苏华兰药用新材料股份有限公司 | Remodeling coated rubber plug |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017167175A1 (en) * | 2016-03-29 | 2017-10-05 | 江苏华兰药用新材料股份有限公司 | Membrane-coated rubber plug and method for producing same |
| CN106214483A (en) * | 2016-08-31 | 2016-12-14 | 上海太平洋实业有限公司 | A kind of arc steps double-colored composite cover of medical transfusion goods |
| CN111568759A (en) * | 2019-09-05 | 2020-08-25 | 深圳艾欣达伟医药科技有限公司 | Packaging bottle for AST-3424 injection, packaging kit and method |
| WO2021043275A1 (en) * | 2019-09-05 | 2021-03-11 | 深圳艾欣达伟医药科技有限公司 | Packaging bottle and packaging kit for injection, and filling, stoppering and capping device and method |
| CN111568759B (en) * | 2019-09-05 | 2023-08-22 | 深圳艾欣达伟医药科技有限公司 | Packaging bottle for AST-3424 injection and packaging kit and method |
| CN112409710A (en) * | 2020-11-03 | 2021-02-26 | 山东省药用玻璃股份有限公司 | Freeze-drying film-coated butyl rubber plug and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| JP3222491U (en) | 2019-08-08 |
| WO2017167175A1 (en) | 2017-10-05 |
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Legal Events
| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160615 |