CN105640592B - A kind of colorful bloodstream frame Related Computational Methods - Google Patents

A kind of colorful bloodstream frame Related Computational Methods Download PDF

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CN105640592B
CN105640592B CN201610159815.3A CN201610159815A CN105640592B CN 105640592 B CN105640592 B CN 105640592B CN 201610159815 A CN201610159815 A CN 201610159815A CN 105640592 B CN105640592 B CN 105640592B
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frame
energy
threshold
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blood flow
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CN105640592A (en
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孙瑞超
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Shenzhen Anasonic Bio-Medical Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/06Measuring blood flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48Diagnostic techniques
    • A61B8/488Diagnostic techniques involving Doppler signals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves

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Abstract

The present invention relates to a kind of colorful bloodstream frame Related Computational Methods, including calculate frame correlation coefficient Coef, the energy/amplitude/threshold speed and decaying related coefficient decaycoef that reading system defines, and energy threshold is used for whole control and judgement;Judge whether current point blood flow energy reaches energy threshold 1, if current point blood flow energy is not up to energy threshold 1, point output directly uses previous frame result;Otherwise it enters using energy threshold 2 and carries out the judgment processing steps in blood flow velocity direction;Judge whether current frame position and previous frame same position are in the same direction by the multiplication of before and after frames point, if in the same direction, to processing in the same direction;Otherwise reverse process is arrived.Corresponding frame relevant effect had not only may be implemented in the present invention, but also was unlikely to the confusion that treatment process causes data;It can choose different associative modes, to realize optimal diagnostic value;Tupe selection in the same direction, can farthest optimize clinic and need effect listed by the present invention.

Description

A kind of colorful bloodstream frame Related Computational Methods
Technical field
The invention belongs to ultrasonic imaging technique fields, are specifically related to a kind of colorful bloodstream frame Related Computational Methods.
Background technique
Color flow angiography technical application in compuscan, is measured in diagnosis object using Doppler effect The motion state and parameter of blood flow or tissue, the direction of motion, speed and energy including blood flow.When clinical diagnosis, usually with Red mark indicates opposite direction towards the blood flow that probe orientation moves with blue.
It is related by using the data of before and after frames since signal is all no symbol luminance signal in conventional two-dimensional imaging, It can realize that the display of diagnostic signal enhances using simple first order IIR filtering device, and filtration fraction noise, enhance doctor's Diagnose confidence.
This method is used widely in ultrasonic two dimension, is worked well.But in colorful blood, due to existing just Reversely, this method is just not suitable for.When blood flow occurs reversed, the characteristic of IIR makes directly to handle meeting according to original method Make blood flow disorder.
A kind of simple solution be only to it is in the same direction when processing, but be equivalent to restarting IIR in this way, it is contemplated that IIR Filter stable state needs the time, this will make frame correlation filter be chronically at unstable state.
United States Patent (USP) USP2008/0298651 A1, provides a kind of method of reverse process, by it is reversed to blood flow when It is handled, so that IIR be made not adversely affected by blood flow, is always maintained at preferable state;USP2008/0298651 A1 is provided A kind of reverse process method although seem and solve inverse problem, so that filtering characteristic is applicable in when reversed, but it is real Only handled on border it is reversed after first frame, its reverse process easily generates bigger confusion when the second frame.
Summary of the invention
It is an object of the invention to overcome the deficiencies of the prior art and provide a kind of frame phases based on clinical application specificity analysis Corresponding frame relevant effect had not only may be implemented in pass method, but also was unlikely to the confusion that treatment process causes data, and the present invention solves it The technical solution that technical problem uses are as follows:
A kind of colorful bloodstream frame Related Computational Methods, comprising the following steps:
Step s1: previous frame data and this frame data are obtained;
Step s2: current system frame per second is obtained;
Step s3: calculating frame correlation coefficient coef according to current frame rate and frame correlation coefficient gear,
Wherein FR is current frame rate, tpIt is the control coefrficient according to present frame correlation gear selection;
Step s4: the energy/amplitude/threshold speed and decaying related coefficient decaycoef that reading system defines, wherein There are two energy thresholds: energy threshold 1, controls for whole, i.e., whether does frame relevant treatment and energy threshold 2, for speed Judgement processing when spending reversed;
Step s5: judging whether current point blood flow energy reaches energy threshold 1, if current point blood flow energy is not up to energy Threshold value 1 is measured, then point output directly uses previous frame result;Otherwise it enters using energy threshold 2 and carries out blood flow velocity The judgment processing steps in direction;
Step s6: judge whether current frame position and previous frame same position are in the same direction by the multiplication of before and after frames point, if together To, then arrive in the same direction processing;Otherwise reverse process is arrived.
The further technical solution of the present invention further include:
In step s6, the treatment process in the same direction are as follows: selection diagnostic mode first obtains the diagnosis from Parameter File The corresponding associative mode of mode, if associative mode is 1, at Velout=Velcur*coef+Velpre* (1-coef) Reason, wherein coef is the calculated result in step s3, and Velcur is present frame input speed value, and Velpre is that previous frame frame is related As a result it exports;If associative mode is 0, the knot after being multiplied with previous frame relevant speed result with attenuation coefficient to present speed Fruit is compared, and exports wherein biggish one of absolute value.
The inverse process are as follows: judge three groups of threshold values, be energy threshold 2, amplitude threshold and speed absolute value respectively Threshold value, three groups reach given threshold, and directly output is as a result, the attenuation results for otherwise exporting the frame correlated results of previous frame are Velpre*decaycoef。
The inverse process are as follows: only can judge energy threshold 2, appointing in amplitude threshold or speed absolute value threshold value Whether one reach given threshold, can also increase echo absolute amplitude etc. itself it is judged that project.
After the result output, all the way for showing, saves be used for subsequent processing all the way.
In step s1, the data include speed data and energy datum.
In step s4, the energy threshold can be replaced using the combination of echo absolute amplitude, variance and energy.
Compared with prior art, advantageous effects of the invention are as follows: 1, that corresponding frame had both may be implemented in the present invention was related Effect, and it is unlikely to the confusion that treatment process causes data;2, mode when will be according to applications of ultrasound is distinguished, as velocity variations are fast The slow different piece with velocity variations, can choose different associative modes, to realize optimal diagnostic value;3, of the invention Listed tupe in the same direction selection, can farthest optimize clinic and need effect, can be adaptively selected, can also within Switch selection is set, rather than simply front and back is related.
Detailed description of the invention
Fig. 1 is frame relevant treatment flow chart of the invention;
Fig. 2 is the structural block diagram of general ultrasonic system;
Fig. 3 is the frame relevant effect figure of a specific embodiment of the invention.
Specific embodiment
Below in conjunction with attached drawing, specific embodiments of the present invention will be described in more detail.
Referring to Fig. 2, a kind of colorful bloodstream frame Related Computational Methods, comprising the following steps:
Step s1: previous frame data and this frame data are obtained;
Step s2: current system frame per second is obtained;
Step s3: calculating frame correlation coefficient coef according to current frame rate and frame correlation coefficient gear,
Wherein FR is current frame rate, tpIt is the control coefrficient according to present frame correlation gear selection;
Step s4: the energy/amplitude/threshold speed and decaying related coefficient decaycoef that reading system defines, wherein There are two energy thresholds: energy threshold 1, controls for whole, i.e., whether does frame relevant treatment and energy threshold 2, for speed Judgement processing when spending reversed;
Step s5: judging whether current point blood flow energy reaches energy threshold 1, if current point blood flow energy is not up to energy Threshold value 1 is measured, then point output directly uses previous frame result;Otherwise it enters using energy threshold 2 and carries out blood flow velocity The judgment processing steps in direction;
Step s6: judge whether current frame position and previous frame same position are in the same direction by the multiplication of before and after frames point, if together To, then arrive in the same direction processing;Otherwise reverse process is arrived.
In the present invention, in step s1, data include speed data and energy datum;Calculating frame correlation coefficient coef Afterwards, it first determines whether blood flow energy reaches the threshold value of setting, if reached, carries out below step, otherwise directly in output One frame end value, this is in order to avoid unstable point occurs.
Differentiation to blood flow velocity: if current frame position has been compared reversely with previous frame same position, by following anti- To processing, otherwise by positive processing.
Preferably, in the present invention, when reverse process, we represent current energy value with POWcur, represent energy with POWth Measure given threshold;MAGcur represents current amplitude value, and MAGth represents amplitude threshold;| Vel | indicate present speed absolute value, Velth indicates threshold speed, directly defeated using the new result of present frame if energy, speed, amplitude are all larger than given threshold Out, i.e. Velout=Velcur, such case should retain it is thought that true reversed blood flow signal.If any of them One is not achieved, then it is assumed that present frame at this signal it is unreliable, exported using the pad value of previous frame result, at this time Velout= Velpre*decaycoef, decaycoef is the decaying related coefficient that system defines in step s4 here, and Velpre is previous frame As a result, all the way for showing, saving be used for subsequent processing all the way after the output of Velout result;Reverse process can also only judge Whether energy threshold 2, any one of amplitude threshold or speed absolute value threshold value reach given threshold, and it is exhausted can also to increase echo To amplitude etc. itself it is judged that project.
If two frame of front and back is in the same direction herein, to be selected according to mode.If evanescent mode, such case will judge The absolute value of current value and the pad value order of magnitude of previous frame select wherein biggish output, we are with Abs (Vel) table Show the absolute value of current value, the absolute value of previous frame is indicated with abs (Velpre), then the pad value absolute value of previous frame is Abs (Velpre) * decaycoef, if Abs (Vel) > abs (Velpre) * decaycoef, Velout=Velcur;Otherwise Velout=Velpre*decaycoef.This is while maximum value to be made to can produce sunset glow effect to keep speed maximum value, Make clinical diagnosis more advantageous.It is fixed to use Velout=Velcur* if it is another associative mode then regardless of front and back size Coef+Velpre* (1-coef) processing.
In the present invention, global threshold switch process is carried out to frame correlation, random noise can be limited in this way, blood flow is shown Influence.Other than using energy threshold, the combination of echo absolute amplitude, variance and energy can also be used.
Different frame relevant ways is used to different checking modes, can choose when then fast for frame per second more in the same direction Simple IIR filtering direction [Velout=Velcur*coef+Velpre* (1-coef)], becomes directional velocity when in the same direction When change is very fast or frame per second is lower, it is contemplated that the initialization time of IIR influences, and uses the decaying of preceding value and current value the larger value Output, can be such that larger speed blood flow retains more long in this way, more meet the characteristic of clinical application.It is wherein related to checking mode , it can initially be set in advance by system, certain condition such as frame per second and velocity reversal's change rate, Dynamic Execution also can be set.
The present invention according to threshold value interpretation in the treatment process of reversed blood flow, determining to use current value or previous frame phase Pair pad value, deterministic process can be energy threshold 2, and three combinations of amplitude threshold or speed absolute value are also possible to it In any one, can also increase echo absolute amplitude etc. itself it is judged that project.Due to it is reversed when have a zero passage process, because This absolute value, which compares, to be used.
The present invention when handling reversed, is handled by aliasing hypothesis.And the true positive and negative right and wrong of many times blood flow Normal normal thing, aliasing is scale [velocity scale] insufficient a few cases.It can band letter by aliasing processing all situations The possibility of number disorder.And use reversed threshold value interpretation treatment process, then it can preferably retain the true blood flow form of clinical needs.
Tupe selection in the same direction, can farthest optimize clinic and need effect listed by the present invention, can be adaptive It should select, can also be selected with built-in switch, rather than simply front and back is related.
Referring to Fig. 1, Fig. 1 is the block diagram of general ultrasonic system, the mode that system control module is selected according to user passes through Transmit circuit emits the transmitted waveform of specific frequency, voltage, carrys out incentive probe.For B imaging pattern, broadband hair is generally selected It penetrates, i.e., less transmit cycle, corresponds to higher voltage in this way;For C, that is, blood flow imaging mode, then relatively narrow transmitting is selected Bandwidth or more transmit cycle, in this case in order to ensure acoustical power is not exceeded, usual voltage is then lower.Probe usually by PZT [piezoelectric, piezoelectric ceramics] composition, according to the needs of clinical application, has differentiation from frequency and shape, usually wears Thoroughly demanding use low-frequency probe, resolution requirement is high and to be looked for second solution to penetrating, then high frequency probe can be used;If It is abdominal applications, it is contemplated that the structure of human abdomen generally will use convex battle array;Linear array is generally used for superficial tissues.But nothing It is all that the transmitted waveform of corresponding frequencies is converted to ultrasonic wave by the probe of which kind of frequency or shape, ultrasonic wave is in diagnosis pair As organizing it is to propagate, echo is generated, echo is converted to electric signal by probe again.This electric signal, which passes through, has high_voltage isolation Circuit is received, transmitting signal biggish in this way can be cut, and only retain faint reception signal.Believe by the echo of human body It number is mv grades, and emitting voltage is usually 10v rank, therefore has higher requirement to circuit is received.Additionally due at present Probe is that array is probe, this means that the signal between different accesses needs synchronous and enhances, this process, that is, wave beam Synthesis, the SNR[signal-to-noise ratio of echo had both can be improved in he], focusing and Receiving apodization also may be implemented.The above links, including Subsequent link is the progress under the synchronization of system control.
The output of Beam synthesis is generally termed RF [radiofrequency signal], this is because the signal after this is in sample frequency Modulated useful signal, after detection and post-processing, so that it may show as needed.The main process of signal processing is exactly Detection usually uses quadrature demodulation and low pass is added to realize;For C signal processing, the signal after detection also needs to carry out auto-correlation Operation, auto-correlation computation is the result is that NDR, these three are intermediate variables, after certain conversion, so that it may obtain blood flow signal VTP [velocity, tolerance, Power], V therein is that our blood flow velocity mentioned show that it is that have direction 's;P is speed without symbolic formulation mode, substantially and speed signal.
B post-processing includes log-compressed, dynamic range transform, gain control, frame correlation, smooth etc..
C post-processing includes gain process, space smoothing, frame correlation, priority control etc., and the method for the present invention is mainly used in The frame relevant portion of C post-processing.Gain process is mainly to show the abundant program of blood flow, and usually requiring that can incite somebody to action when gain minimum The blood flow overwhelming majority closes display, and can largely show all blood flow signals, including noise when maximum.Space smoothing master If filtering individual abnormal points and part edge discontinuous problem.Priority control be mainly by the velocity magnitude of blood flow, Variance, energy and corresponding B processing result, selectivity show or do not show blood flow, so that blood flow shows that result is most advantageous There is clinical diagnosis.
Referring to Fig. 3, Fig. 3 illustrates a kind of frame relevant effect, solid line is importation in figure, anti-due to introducing one To noise, when this inverse noise is unsatisfactory for interpretation threshold value, we can be removed this abnormal point by foregoing invention, As a result dotted portion above is just shown.
The foregoing is merely a prefered embodiment of the invention, is not intended to limit the invention, and protection scope of the present invention is with appended Subject to claim, other its all structures and principle are same or similar with the present invention, should be included in protection of the invention Within the scope of.

Claims (7)

1. a kind of colorful bloodstream frame Related Computational Methods, which comprises the following steps:
Step s1: previous frame data and this frame data are obtained;
Step s2: current system frame per second is obtained;
Step s3: calculating frame correlation coefficient coef according to current frame rate and frame correlation coefficient gear,
Wherein FR is current frame rate, tpIt is the control coefrficient according to present frame correlation gear selection;
Step s4: energy/amplitude/threshold speed that reading system defines and decaying related coefficient decaycoef, wherein energy There are two threshold values: energy threshold 1, controls for whole, i.e., whether does frame relevant treatment and energy threshold 2, anti-for speed To when judgement processing;
Step s5: judging whether current point blood flow energy reaches energy threshold 1, if current point blood flow energy is not up to energy cut-off Value 1, then point output directly uses previous frame result;Otherwise it enters using energy threshold 2 and carries out blood flow velocity direction Judgment processing steps;
Step s6: judging whether current frame position and previous frame same position are in the same direction by the multiplication of before and after frames point, if in the same direction, To processing in the same direction;Otherwise reverse process is arrived.
2. a kind of colorful bloodstream frame Related Computational Methods according to claim 1, which is characterized in that in step s6, institute State treatment process in the same direction are as follows: selection diagnostic mode first obtains the corresponding associative mode of the diagnostic mode, such as from Parameter File Fruit associative mode is 1, then handles by Velout=Velcur*coef+Velpre* (1-coef), and wherein coef is in step s3 Calculated result, Velcur be present frame input speed value, Velpre be previous frame frame correlated results export;If associative mode It is 0, then compared with the result after being multiplied with previous frame relevant speed result with decaying related coefficient decaycoef to present speed, And export wherein biggish one of absolute value.
3. a kind of colorful bloodstream frame Related Computational Methods according to claim 1, which is characterized in that the reverse process mistake Journey are as follows: judge three groups of threshold values, be energy threshold 2, amplitude threshold and speed absolute value threshold value respectively, three groups reach given threshold , directly output as a result, otherwise export previous frame frame correlated results attenuation results, that is, Velpre*decaycoef, wherein Velpre is previous frame result.
4. a kind of colorful bloodstream frame Related Computational Methods according to claim 3, which is characterized in that the reverse process mistake Journey are as follows: only judge whether energy threshold 2, any one of amplitude threshold or speed absolute value threshold value reach given threshold, or Increase echo absolute amplitude and judges project.
5. a kind of colorful bloodstream frame Related Computational Methods according to claim 3, which is characterized in that the result output Afterwards, it all the way for showing, saves be used for subsequent processing all the way.
6. a kind of colorful bloodstream frame Related Computational Methods according to claim 1, which is characterized in that in step s1, institute It states previous frame data and this frame data includes speed data and energy datum.
7. a kind of colorful bloodstream frame Related Computational Methods according to claim 1, which is characterized in that in step s4, institute Energy threshold is stated to replace using the combination of echo absolute amplitude, variance and energy.
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CN109363722B (en) * 2018-11-29 2021-08-06 武汉中旗生物医疗电子有限公司 Method and device for suppressing motion artifact in color flow imaging

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CN102113900A (en) * 2010-01-05 2011-07-06 深圳迈瑞生物医疗电子股份有限公司 Relevant method and device for color blood flow dynamic frame
US20110301470A1 (en) * 2010-06-04 2011-12-08 Takeshi Sato Ultrasonic diagnostic apparatus

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Publication number Priority date Publication date Assignee Title
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CN101416885A (en) * 2007-10-22 2009-04-29 深圳迈瑞生物医疗电子股份有限公司 Frame equilibration circuit for ultrasonic imaging system
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