CN105597233A - Heart pacemaker with noncontact power supply function - Google Patents

Heart pacemaker with noncontact power supply function Download PDF

Info

Publication number
CN105597233A
CN105597233A CN201610069613.XA CN201610069613A CN105597233A CN 105597233 A CN105597233 A CN 105597233A CN 201610069613 A CN201610069613 A CN 201610069613A CN 105597233 A CN105597233 A CN 105597233A
Authority
CN
China
Prior art keywords
circuit
power supply
contact power
heart
pacemaker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201610069613.XA
Other languages
Chinese (zh)
Other versions
CN105597233B (en
Inventor
周成虎
陈朝阳
张秋慧
贾贞贞
张菲菲
许峰宽
周建炜
朱永彪
马楚欣
李柏松
袁勋
邢伟伟
刘磊
贾立冬
吴红波
吴涛
张坤
陈冰洋
王振涛
王京
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Henan University of Science and Technology
Original Assignee
Henan University of Science and Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henan University of Science and Technology filed Critical Henan University of Science and Technology
Priority to CN201610069613.XA priority Critical patent/CN105597233B/en
Publication of CN105597233A publication Critical patent/CN105597233A/en
Application granted granted Critical
Publication of CN105597233B publication Critical patent/CN105597233B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362Heart stimulators
    • A61N1/3625External stimulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/103Measuring devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
    • A61B5/1116Determining posture transitions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/346Analysis of electrocardiograms
    • A61B5/349Detecting specific parameters of the electrocardiograph cycle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802Sensor mounted on worn items
    • A61B5/6804Garments; Clothes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362Heart stimulators
    • A61N1/365Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/36592Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by the heart rate variability

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Pathology (AREA)
  • Physiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Dentistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Electrotherapy Devices (AREA)

Abstract

本发明公开了一种具有非接触供电功能的心脏起搏器,包括蓄电池、外置起搏器电路和体内能量接收装置,蓄电池与外置起搏器电路相连接,外置起搏器电路外端设有无线心电传感器,无线心电传感器安装在体外心脏处,体内能量接收装置设置在左肩皮肤内,外置起搏器电路与体内能量接收装置通过电磁耦合相连接,体内能量接收装置通过电极与心脏相连接。本发明通过对心电信号的测量利用心率变异特性判断心脏的疲劳程度,控制需要提供的脉冲电压的幅值和导通刺激时间;心电信号检测滤波电路、蓄电池和非接触供电原边电路均安装在体外,仅将非接触供电副边电路安装在患者体内,大大减少了内置电路的体积,且不再需要定期手术以更换电池。

The invention discloses a cardiac pacemaker with non-contact power supply function, which comprises a storage battery, an external pacemaker circuit and an energy receiving device in the body, the storage battery is connected with the external pacemaker circuit, and the external pacemaker circuit There is a wireless ECG sensor at the end, the wireless ECG sensor is installed at the heart outside the body, the energy receiving device in the body is set in the skin of the left shoulder, the external pacemaker circuit is connected with the energy receiving device in the body through electromagnetic coupling, and the energy receiving device in the body passes through Electrodes are connected to the heart. The present invention judges the degree of fatigue of the heart by measuring the heart rate variation characteristic through the measurement of the electrocardiogram signal, and controls the amplitude of the pulse voltage and the conduction stimulation time to be provided; Installed outside the body, only the non-contact power supply secondary circuit is installed in the patient's body, which greatly reduces the volume of the built-in circuit, and no longer requires regular surgery to replace the battery.

Description

具有非接触供电功能的心脏起搏器Pacemaker with contactless power supply

技术领域 technical field

本发明涉及心脏起搏器的技术领域,具体涉及一种具有非接触供电功能的心脏起搏器,能实现在体外对心脏的跳动状态进行监测和起搏,属于医疗电子的领域。 The invention relates to the technical field of cardiac pacemakers, in particular to a cardiac pacemaker with a non-contact power supply function, capable of monitoring and pacing the beating state of the heart outside the body, and belongs to the field of medical electronics.

背景技术 Background technique

心脏起搏器用于对人体心脏起搏作辅助刺激,通常安装在病人左肩下的体内皮肤,在左前胸的皮肤下置入起搏器,使皮肤撑起构成囊袋,在左前胸的锁骨下的静脉穿刺通入电极,电极由静脉通到心脏并由前端螺纹钩刺入心脏的内侧进行固定,如图1所示。由于传统的起搏器通常比较大,安装后患者的皮肤很长时间不能闭合,洗澡、运动受到限制。患者所受痛苦无法言表,有些患者甚至足不出户,许多人无法上班、工作和跑步等剧烈运动。 The cardiac pacemaker is used for auxiliary stimulation of human heart pacing. It is usually installed on the skin of the patient's body under the left shoulder. The pacemaker is placed under the skin of the left chest to make the skin prop up to form a pouch. It is placed under the clavicle of the left chest The venipuncture leads to the electrode, and the electrode leads from the vein to the heart and is fixed by the threaded hook at the front end piercing the inner side of the heart, as shown in Figure 1. Because traditional pacemakers are usually relatively large, the patient's skin cannot be closed for a long time after installation, and bathing and exercise are restricted. The suffering of patients is beyond words, some patients even stay at home, and many people cannot go to work, work and strenuous exercise such as running.

由于传统的起搏器内置一次性电池,这样的心脏起搏器要想保持10年左右长时间的工作,必须要做到足够大,而且为了节省电量不能做剧烈运动,还要定期的更换。当皮肤几年后刚刚闭合,能够洗澡,出汗也不会浸入体内的时候,下一次手术又开始了,患者的生存质量仅维持在最低的水平。 Since the traditional pacemaker has a built-in disposable battery, such a pacemaker must be large enough to keep working for about 10 years, and it must be replaced regularly in order to save power and cannot do strenuous exercise. When the skin has just closed a few years later, it is possible to take a shower, and the sweat does not soak into the body, and the next operation begins again, and the patient's quality of life is only maintained at the lowest level.

也有学者提出了基于无线供电的起搏器,但这些起搏器仍然需要内置电池和无线通信电路、检测电路,起搏器的体积无法缩小到手术后皮肤完全闭合的程度。 Some scholars have also proposed pacemakers based on wireless power supply, but these pacemakers still need built-in batteries, wireless communication circuits, and detection circuits. The size of the pacemaker cannot be reduced to the extent that the skin is completely closed after surgery.

发明内容 Contents of the invention

为了解决上述技术问题,本发明提供了一种具有非接触供电功能的心脏起搏器,只需在患者体内装设体内能量接收装置,体外检测心电信号和采用推算电极电压方法进行非接触供电,不需要直接检测心脏电极两侧的电压,也不需要加装与外置通信电路,减小植入的整体体积,延长了使用寿命,能够永久工作不需更换,使患者避免多次手术的痛苦。 In order to solve the above technical problems, the present invention provides a cardiac pacemaker with a non-contact power supply function, which only needs to install an internal energy receiving device in the patient's body, detect ECG signals outside the body and use the method of estimating electrode voltage for non-contact power supply , does not need to directly detect the voltage on both sides of the heart electrode, and does not need to install an external communication circuit, which reduces the overall volume of the implant, prolongs the service life, and can work permanently without replacement, so that patients can avoid multiple operations. pain.

为了达到上述目的,本发明的技术方案是:一种具有非接触供电功能的心脏起搏器,包括蓄电池、外置起搏器电路和体内能量接收装置,蓄电池与外置起搏器电路相连接,外置起搏器电路外端设有无线心电传感器,无线心电传感器安装在体外心脏处,体内能量接收装置设置在左肩皮肤内,外置起搏器电路与体内能量接收装置通过电磁耦合相连接,体内能量接收装置通过电极与心脏相连接。 In order to achieve the above object, the technical solution of the present invention is: a cardiac pacemaker with a non-contact power supply function, including a battery, an external pacemaker circuit and an energy receiving device in the body, and the battery is connected to the external pacemaker circuit , the outer end of the external pacemaker circuit is equipped with a wireless ECG sensor, the wireless ECG sensor is installed at the heart outside the body, the energy receiving device in the body is set in the skin of the left shoulder, and the external pacemaker circuit and the energy receiving device in the body are electromagnetically coupled The energy receiving device in the body is connected with the heart through electrodes.

所述体内能量接收装置包括非接触供电副边线圈、整流电路、滤波电路和电极接口,非接触供电副边线圈通过电磁耦合与非接触供电原边线圈相连接,非接触供电副边线圈与整流电路相连接,整流电路与滤波电路相连接,滤波电路与电极接口相连接,电极接口与电极相连接。 The energy receiving device in the body includes a non-contact power supply secondary coil, a rectifier circuit, a filter circuit and an electrode interface, the non-contact power supply secondary coil is connected with the non-contact power supply primary coil through electromagnetic coupling, and the non-contact power supply secondary coil is connected to the The circuits are connected, the rectification circuit is connected with the filter circuit, the filter circuit is connected with the electrode interface, and the electrode interface is connected with the electrode.

所述外置起搏器电路包括信号检测滤波电路、控制电路、非接触供电原边电路和非接触供电原边线圈,无线心电传感器与信号检测滤波电路相连接,信号检测滤波电路与控制电路相连接,控制电路与非接触供电原边电路相连接,非接触供电原边电路与非接触供电原边线圈相连接。 The external pacemaker circuit includes a signal detection filter circuit, a control circuit, a non-contact power supply primary circuit and a non-contact power supply primary coil, the wireless ECG sensor is connected to the signal detection filter circuit, and the signal detection filter circuit is connected to the control circuit The control circuit is connected with the primary circuit of the non-contact power supply, and the primary circuit of the non-contact power supply is connected with the primary coil of the non-contact power supply.

所述控制电路包括三轴陀螺仪、A/D转换电路、数据处理分析电路、疲劳程度判断电路和输出控制电路,A/D转换电路与信号检测滤波电路相连接,三轴陀螺仪、A/D转换电路分别与数据处理分析电路相连接,数据处理分析电路与疲劳程度判断电路相连接,疲劳程度判断电路与输出控制电路相连接,输出控制电路与非接触供电原边电路相连接。 The control circuit includes a three-axis gyroscope, an A/D conversion circuit, a data processing analysis circuit, a fatigue degree judgment circuit and an output control circuit, the A/D conversion circuit is connected with a signal detection filter circuit, and the three-axis gyroscope, A/D The D conversion circuit is respectively connected with the data processing and analysis circuit, the data processing and analysis circuit is connected with the fatigue degree judgment circuit, the fatigue degree judgment circuit is connected with the output control circuit, and the output control circuit is connected with the non-contact power supply primary side circuit.

所述无线心电传感器以可穿戴方式安装在体外心脏附近的围胸服装内,非接触供电原边线圈和非接触供电副边线圈平行安装在左肩下,非接触供电原边线圈和非接触供电副边线圈之间的距离在0.3~0.5cm之间,非接触供电原边线圈和非接触供电副边线圈以非接触方式传输磁场能量。 The wireless ECG sensor is installed in the corset garment near the external heart in a wearable manner, the primary coil of the non-contact power supply and the secondary coil of the non-contact power supply are installed under the left shoulder in parallel, the primary coil of the non-contact power supply and the secondary coil of the non-contact power supply The distance between the secondary coils is between 0.3 and 0.5 cm, and the non-contact power supply primary coil and the non-contact power supply secondary coil transmit magnetic field energy in a non-contact manner.

所述非接触供电副边线圈是用细铜漆包线绕制而成的线圈,整流电路和滤波电路为贴片元件。 The non-contact power supply secondary coil is a coil made of thin copper enameled wire, and the rectifier circuit and filter circuit are chip components.

其工作原理是:无线心电传感器采集使用者的心电信号,信号检测滤波电路利用其内的运算放大器将微弱的心电信号放大、滤波、电压抬升最终生成心电模拟信号的波形;A/D转换电路将心电模拟信号波形转换成数字信号送到数据处理分析电路进行分析处理,由疲劳程度判断电路根据心电信号的处理结果判断心脏的状态,输出控制电路控制非接触供电原边电路的的开关器件的占空比t on,由非接触供电原边线圈对非接触供电副边线圈传递能量,体内能量接收装置整流滤波后由电极对心脏实施起搏刺激。 Its working principle is: the wireless ECG sensor collects the user's ECG signal, and the signal detection filter circuit uses the operational amplifier inside to amplify, filter, and raise the weak ECG signal to finally generate the waveform of the ECG analog signal; A/ The D conversion circuit converts the ECG analog signal waveform into a digital signal and sends it to the data processing and analysis circuit for analysis and processing. The fatigue degree judgment circuit judges the state of the heart according to the processing results of the ECG signal, and the output control circuit controls the non-contact power supply primary circuit. The duty cycle t on of the switching device is used to transfer energy from the primary coil of the non-contact power supply to the secondary coil of the non-contact power supply, and the internal energy receiving device rectifies and filters the heart through the electrodes to perform pacing stimulation.

所述疲劳程度判断电路判断心脏疲劳的方法:测量心电信号波形RR波峰间的时间差,计算心率的变异特性,若RR波峰间期的时间大于正常的时间范围则判定为疲劳。 The method for judging heart fatigue by the fatigue degree judging circuit: measuring the time difference between RR peaks of the electrocardiographic signal waveform, calculating the variation characteristics of heart rate, and judging as fatigue if the time between RR peaks is greater than the normal time range.

所述输出控制电路通过控制非接触供电原边电路开关器件的占空比t on以改变电极的输出电压u o ,输出控制电路通过判断和控制非接触供电原边电路总的供电时间,以改变电极输出电压u o 的持续时间,持续时间是一次心电脉冲的导通刺激时间t totThe output control circuit changes the output voltage u o of the electrode by controlling the duty ratio t on of the switching device of the primary side circuit of the non-contact power supply, and the output control circuit changes the output voltage u o of the electrode by judging and controlling the total power supply time of the primary side circuit of the non-contact power supply The duration of the electrode output voltage u o , the duration is the conduction stimulation time t tot of an electrocardiographic pulse.

所述三轴陀螺仪测定三维空间三个坐标轴6个方向的位置、移动轨迹和加速度,将得到的信号送到数据处理和分析电路处理进行分析处理,当检测到身体移动时,输出控制电路立即加强心脏起搏刺激信号,增大刺激的电压幅值并延长心电脉冲的导通刺激时间t totThe three-axis gyroscope measures the positions, moving trajectories and accelerations of the three coordinate axes in the three-dimensional space, and sends the obtained signals to the data processing and analysis circuit for analysis and processing. When the body movement is detected, the output control circuit Immediately strengthen the cardiac pacing stimulation signal, increase the voltage amplitude of the stimulation and prolong the conduction stimulation time t tot of the electrocardiographic pulse.

本发明通过对心电信号的测量,利用心率变异特性判断心脏的疲劳程度,由疲劳程度判断模块判断疲劳程度,通过输出控制电路控制非接触供电原边电路向非接触供电副边线圈提供的脉冲电压的幅值大小和刺激时间长短;同时,通过三轴陀螺仪测量患者的身体变化,实现主动起搏的判断。与传统的起搏器不同的,本发明将心电信号检测滤波电路、心脏起搏器、电池和非接触供电原边电路均安装在身体之外,仅将非接触供电副边电路安装在患者左前胸皮下囊袋内,这样可以大大减少内置电路的体积,且不再需要定期手术以更换起搏器的电池。本发明基于无线供电技术的起搏器,无需内置电池、无线通信电路和检测电路,体内能量接收装置不需要直接检测心脏电极两侧电压,也不需要加装与外置起搏器电路相匹配的通信电路,与以往的内置双腔起搏器相比,体内能量接收装置的体积减小到原来的1/4以下,厚度减小到原来的1/3以下,体内能量接收装置植入后能够永久工作不需更换。 The present invention judges the fatigue degree of the heart by measuring the ECG signal, using the heart rate variation characteristic, judges the fatigue degree by the fatigue degree judging module, and controls the pulse provided by the non-contact power supply primary side circuit to the non-contact power supply secondary side coil through the output control circuit The magnitude of the voltage and the length of the stimulation time; at the same time, the patient's body changes are measured by the three-axis gyroscope to realize the judgment of active pacing. Different from the traditional pacemaker, the present invention installs the ECG signal detection filter circuit, cardiac pacemaker, battery and non-contact power supply primary circuit outside the body, and only the non-contact power supply secondary circuit is installed on the patient In the subcutaneous pouch of the left chest, the volume of the built-in circuit can be greatly reduced, and the need for regular surgery to replace the pacemaker battery is no longer required. The pacemaker based on the wireless power supply technology of the present invention does not need a built-in battery, wireless communication circuit and detection circuit, and the energy receiving device in the body does not need to directly detect the voltage on both sides of the heart electrodes, and does not need to be equipped with an external pacemaker circuit to match Compared with the previous built-in dual-chamber pacemaker, the volume of the energy receiving device in the body is reduced to less than 1/4 of the original, and the thickness is reduced to less than 1/3 of the original. After the implantation of the energy receiving device in the body Can work permanently without replacement.

附图说明 Description of drawings

为了更清楚地说明本发明实施例或现有技术中的技术方案,下面将对实施例或现有技术描述中所需要使用的附图作简单地介绍,显而易见地,下面描述中的附图仅仅是本发明的一些实施例,对于本领域普通技术人员来讲,在不付出创造性劳动的前提下,还可以根据这些附图获得其他的附图。 In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings that need to be used in the description of the embodiments or the prior art. Obviously, the accompanying drawings in the following description are only These are some embodiments of the present invention. Those skilled in the art can also obtain other drawings based on these drawings without creative work.

图1为传统的心脏起搏器安装位置图。 Fig. 1 is a diagram of the installation position of a traditional cardiac pacemaker.

图2为本发明的原理框图。 Fig. 2 is a functional block diagram of the present invention.

图3为本发明的信号检测滤波电路的电路图。 FIG. 3 is a circuit diagram of the signal detection filter circuit of the present invention.

图4为本发明的心电信号波形。 Fig. 4 is the ECG signal waveform of the present invention.

图5为本发明的非接触供电线圈相对位置图。 Fig. 5 is a relative position diagram of the non-contact power supply coil of the present invention.

图6为本发明的电路电压波形。 Fig. 6 is a circuit voltage waveform of the present invention.

具体实施方式 detailed description

下面将结合本发明实施例中的附图,对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有付出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。 The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

一种具有非接触供电功能的心脏起搏器,原理框图如图2所示,包括蓄电池9、外置起搏器电路27和体内能量接收装置11。蓄电池9作为整个装置的电源,为整个装置提供电能支持,蓄电池9与外置起搏器电路27相连接,外置起搏器电路27外端设有无线心电传感器25,无线心电传感器25安装在体外心脏处,体内能量接收装置11设置在左肩皮肤内,外置起搏器电路27与体内能量接收装置11通过电磁耦合相连接,体内能量接收装置11通过电极与心脏相连接。 A cardiac pacemaker with non-contact power supply function, the functional block diagram is shown in FIG. 2 , including a battery 9 , an external pacemaker circuit 27 and an internal energy receiving device 11 . The storage battery 9 is used as the power supply of the whole device, and provides electric energy support for the whole device. Installed at the heart outside the body, the internal energy receiving device 11 is placed in the skin of the left shoulder, the external pacemaker circuit 27 is connected to the internal energy receiving device 11 through electromagnetic coupling, and the internal energy receiving device 11 is connected to the heart through electrodes.

无线心电传感器25以可穿戴方式安装在体外心脏附近的围胸服装内,实现对患者心电信号的采集,无线心电传感器25与外置起搏器电路27相连接。外置起搏器电路27包括信号检测滤波电路1、控制电路12、非接触供电原边电路7和非接触供电原边线圈13,无线心电传感器25与信号检测滤波电路1相连接,信号检测滤波电路1与控制电路12相连接,控制电路12与非接触供电原边电路7相连接,非接触供电原边电路7与非接触供电原边线圈13相连接。 The wireless ECG sensor 25 is installed in the corset garment near the external heart in a wearable manner to realize the collection of the patient's ECG signal. The wireless ECG sensor 25 is connected with the external pacemaker circuit 27 . The external pacemaker circuit 27 includes a signal detection filter circuit 1, a control circuit 12, a non-contact power supply primary side circuit 7 and a non-contact power supply primary side coil 13, a wireless ECG sensor 25 is connected with the signal detection filter circuit 1, and the signal detection The filter circuit 1 is connected with the control circuit 12 , the control circuit 12 is connected with the non-contact power supply primary circuit 7 , and the non-contact power supply primary circuit 7 is connected with the non-contact power supply primary coil 13 .

信号检测滤波电路1对无线心电传感器25采集的心电信号进行处理,生成相应的波形。无线心电传感器25检测得到人体的原始心电信号u dec,由于原始心电信号u dec十分微弱,只有0.05~5mV,因此,信号检测滤波电路1需要对采集的原始心电信号进行放大。信号检测滤波电路1的电路图如图3所示,运算放大器AMP1选择OP07型运算放大器,利用运算放大器AMP1构成二阶低通滤波电路并放大心电信号。低通滤波电路的主要功能是滤除心电信号频带之外的高频干扰,以提高系统信噪比。低通滤波电路的设计上限截止频率为45Hz。运算放大器AMP2构成二阶高通滤波电路,高通滤波电路可以滤除心电信号频带外的低频噪声成分,提高系统信噪比,电路的设计下限截止频率应为0.03Hz,即到达AHA标准所要求的诊断用心电设备相关要求。为避免蓄电池充电时产生的50Hz工频电源干扰,同时保证其它信号毫无衰减地通过,设计了带阻陷波器,运算放大器AMP3和AMP4构成陷波器电路。滤波放大后的心电信号u heart,当原始心电信号u dec输入电压为1mV时,心电信号u heart的输出电压能达到1V左右,即信号检测滤波电路1的放大倍数为1000倍左右。A/D转换电路3的最大输入电压为3.3V,心电信号u heart的输出电压在A/D转换电路3的转换范围之内。 The signal detection filter circuit 1 processes the ECG signals collected by the wireless ECG sensor 25 to generate corresponding waveforms. The wireless ECG sensor 25 detects the original ECG signal u dec of the human body. Since the original ECG signal u dec is very weak, only 0.05-5mV, the signal detection filter circuit 1 needs to amplify the collected original ECG signal. The circuit diagram of the signal detection filter circuit 1 is shown in Figure 3. The operational amplifier AMP1 is an OP07 operational amplifier, and the operational amplifier AMP1 is used to form a second-order low-pass filter circuit and amplify the ECG signal. The main function of the low-pass filter circuit is to filter out high-frequency interference outside the frequency band of the ECG signal to improve the system signal-to-noise ratio. The design upper limit cut-off frequency of the low-pass filter circuit is 45Hz. The operational amplifier AMP2 constitutes a second-order high-pass filter circuit. The high-pass filter circuit can filter out low-frequency noise components outside the frequency band of the ECG signal and improve the system signal-to-noise ratio. The lower limit cut-off frequency of the circuit design should be 0.03Hz, which is required by the AHA standard. Requirements for diagnostic ECG equipment. In order to avoid the 50Hz power frequency interference generated when the battery is charged, and to ensure that other signals pass through without attenuation, a band-stop notch filter is designed, and the operational amplifiers AMP3 and AMP4 form a notch filter circuit. After filtering the amplified ECG signal u heart , when the input voltage of the original ECG signal u dec is 1mV, the output voltage of the ECG signal u heart can reach about 1V, that is, the amplification factor of the signal detection filter circuit 1 is about 1000 times. The maximum input voltage of the A/D conversion circuit 3 is 3.3V, and the output voltage of the ECG signal u heart is within the conversion range of the A/D conversion circuit 3 .

控制电路12由ARM9芯片构成其核心电路,根据心电信号的脉冲波形对患者的疲劳程度做出准确的判断。控制电路12包括三轴陀螺仪2、A/D转换电路3、数据处理分析电路4、疲劳程度判断电路5和输出控制电路6,A/D转换电路3与信号检测滤波电路1相连接,三轴陀螺仪2、A/D转换电路3分别与数据处理分析电路4相连接,数据处理分析电路4与疲劳程度判断电路5相连接,疲劳程度判断电路5与输出控制电路6相连接,输出控制电路6与非接触供电原边电路7相连接,非接触供电原边电路7与非接触供电原边线圈13相连接。 The control circuit 12 is composed of an ARM9 chip as its core circuit, and can accurately judge the fatigue degree of the patient according to the pulse waveform of the ECG signal. The control circuit 12 includes a three-axis gyroscope 2, an A/D conversion circuit 3, a data processing and analysis circuit 4, a fatigue degree judgment circuit 5, and an output control circuit 6. The A/D conversion circuit 3 is connected to the signal detection filter circuit 1, and the three The axial gyroscope 2 and the A/D conversion circuit 3 are respectively connected with the data processing and analysis circuit 4, the data processing and analysis circuit 4 is connected with the fatigue degree judgment circuit 5, the fatigue degree judgment circuit 5 is connected with the output control circuit 6, and the output control The circuit 6 is connected with the non-contact power supply primary side circuit 7 , and the non-contact power supply primary side circuit 7 is connected with the non-contact power supply primary side coil 13 .

体内能量接收装置11包括非接触供电副边线圈14、整流电路8、滤波电路17和电极接口10,非接触供电副边线圈14通过电磁耦合与非接触供电原边线圈13相连接,非接触供电副边线圈14与整流电路8相连接,整流电路8与滤波电路17相连接,滤波电路17与电极接口10相连接,电极接口10与电极相连接。电极包括正电极15和负电极16,正电极15和负电极16的输入端分别与电机接口10相连接,正电极15和负电极16的输出端经心脏动脉插入心脏内部钩在心脏内壁上。因此,心脏内部电极两端的电阻即是非接触供电电路的负载R eq,通过体内能量接收装置11向正电极15、负电极16上施加电压即可实现对心脏的刺激,两个电极之间的电压幅值为1~5V。 The energy receiving device 11 in the body includes a non-contact power supply secondary coil 14, a rectifier circuit 8, a filter circuit 17 and an electrode interface 10. The non-contact power supply secondary coil 14 is connected with the non-contact power supply primary coil 13 through electromagnetic coupling, and the non-contact power supply The secondary coil 14 is connected to the rectifier circuit 8, the rectifier circuit 8 is connected to the filter circuit 17, the filter circuit 17 is connected to the electrode interface 10, and the electrode interface 10 is connected to the electrode. The electrodes include a positive electrode 15 and a negative electrode 16. The input ends of the positive electrode 15 and the negative electrode 16 are respectively connected to the motor interface 10. The output ends of the positive electrode 15 and the negative electrode 16 are inserted into the heart through the cardiac artery and hooked on the inner wall of the heart. Therefore, the resistance at both ends of the electrodes inside the heart is the load Req of the non-contact power supply circuit, and the stimulation of the heart can be realized by applying a voltage to the positive electrode 15 and the negative electrode 16 through the energy receiving device 11 in the body. The voltage between the two electrodes The amplitude is 1~5V.

非接触供电原边线圈13和非接触供电副边线圈14平行安装在左肩下,二者相隔一层人体皮肤和穿戴衣物,同在左肩前下方平行相对位置,非接触供电原边线圈13和非接触供电副边线圈14之间的距离为0.3~0.5cm,如图5所示,非接触供电原边线圈13和非接触供电副边线圈14以非接触方式传输磁场能量。非接触供电副边线圈14是用细铜漆包线绕制而成的线圈,整流电路8、滤波电路17为贴片元件,减少体内能量接收装置11的体积。非接触供电副边线圈14沿着整流电路8、滤波电路17和电极接口10的外边缘绕制,电路及线圈总厚度在2mm以内,加上外壳的厚度不大于3mm,长度和宽度为25mm×25mm以内。 The non-contact power supply primary side coil 13 and the non-contact power supply secondary side coil 14 are installed in parallel under the left shoulder. The distance between the contact power supply secondary coils 14 is 0.3~0.5cm. As shown in FIG. 5 , the non-contact power supply primary coil 13 and the non-contact power supply secondary coil 14 transmit magnetic field energy in a non-contact manner. The non-contact power supply secondary coil 14 is a coil made of thin copper enameled wire, and the rectifier circuit 8 and the filter circuit 17 are chip components, which reduce the volume of the energy receiving device 11 in the body. The non-contact power supply secondary coil 14 is wound along the outer edges of the rectifier circuit 8, the filter circuit 17 and the electrode interface 10, the total thickness of the circuit and the coil is within 2mm, and the thickness of the shell is not more than 3mm, and the length and width are 25mm× Within 25mm.

疲劳程度可分为体力疲劳和精神疲劳,本发明只关注体力疲劳,依据是心脏的跳动情况判断疲劳程度。当患者剧烈运动时心脏跳动的频率增加,但是供血量不足以满足人体运动的需要,心脏跳动的波形异常,此时需要心脏起搏器刺激心脏加大泵送血流的力度;若患者没有进行剧烈的运动,心跳平稳时可以认为疲劳状态为零,不需要心脏起搏器刺激。 The degree of fatigue can be divided into physical fatigue and mental fatigue. The present invention only focuses on physical fatigue, and judges the degree of fatigue based on the beating of the heart. When the patient is exercising vigorously, the frequency of the heart beat increases, but the blood supply is not enough to meet the needs of the human body, and the waveform of the heart beat is abnormal. At this time, a pacemaker is needed to stimulate the heart to increase the intensity of pumping blood; if the patient does not During strenuous exercise, when the heartbeat is stable, it can be considered that the fatigue state is zero, and there is no need for cardiac pacemaker stimulation.

心电信号波形具有一定的特征,信号检测滤波电路处理后的心电信号波形如图4所示,其中,P波:代表心房除极波;QRS波:代表心室除极波;T波:代表心室复极波;U波:后继电位的影响P-R间期,自心房除极开始到心室除极开始之前的时间;QRS间期:代表心室除极所需时间;Q-T间期:代表心室除极和心室复极全过程所需时间;S-T段:代表心室除极结束到复极开始之前的一段时间,此段时间心室肌处于去极化状态,可反映心室的供血状态。 The waveform of the ECG signal has certain characteristics. The waveform of the ECG signal processed by the signal detection filter circuit is shown in Figure 4. Among them, P wave: represents the atrial depolarization wave; QRS wave: represents the ventricular depolarization wave; T wave: represents the Ventricular repolarization wave; U wave: the influence of subsequent potential PR interval, the time from the beginning of atrial depolarization to the beginning of ventricular depolarization; QRS interval: representing the time required for ventricular depolarization; Q-T interval: representing ventricular depolarization and the time required for the whole process of ventricular repolarization; S-T segment: represents a period of time from the end of ventricular depolarization to the beginning of repolarization. During this period, the ventricular muscle is in a depolarized state, which can reflect the blood supply state of the ventricle.

内心率HR(HeartRate,HR)在疲劳中有着明显的反应,影响HR的主要因素是体力负荷,HRV(HeartRateVariability)是指连续心跳间期(R-R间期)的微小起伏,用HRV测定疲劳状态。要得到HRV信号,必须获得心跳间期,为了提高采集HRV信号的准确信,需测量两相邻R波波峰之间的时间差。有研究发现驾驶员驾驶疲劳时其RR间期的标准会随驾驶时间的增加而逐渐增大,心率变异会增大。因此,在这里测量RR波峰间的时间差,计算心率变异情况,若RR波峰间期的时间小于正常的时间范围,则判定为疲劳。计算心率变异情况包括两个内容,一个是RR间期是否在合理范围;另一个是连续心跳速率波动(HeartRateVariability,HRV)。即心跳速度的变化特性(加速度)必须控制在一定范围内,患者的HRV特性超出特性范围值,则意味着心脏功能异常,需要开启起搏器刺激功能。 Heart rate HR (HeartRate, HR) has an obvious response in fatigue. The main factor affecting HR is physical load. HRV (HeartRateVariability) refers to the small fluctuation of continuous heartbeat interval (R-R interval). HRV is used to measure the fatigue state. To obtain the HRV signal, the heartbeat interval must be obtained. In order to improve the accuracy of collecting the HRV signal, it is necessary to measure the time difference between two adjacent R wave peaks. Some studies have found that when the driver is fatigued, the standard RR interval will gradually increase with the increase of driving time, and the heart rate variability will increase. Therefore, the time difference between RR peaks is measured here, and the heart rate variability is calculated. If the time between RR peaks is less than the normal time range, it is judged as fatigue. The calculation of heart rate variability includes two contents, one is whether the RR interval is within a reasonable range; the other is continuous heart rate fluctuation (HeartRateVariability, HRV). That is, the change characteristics (acceleration) of the heartbeat speed must be controlled within a certain range. If the HRV characteristics of the patient exceed the characteristic range value, it means that the heart function is abnormal, and the pacemaker stimulation function needs to be turned on.

此外,由心电图判断心律失常(指心脏搏动的起源部位、频率、节律、传导等任一项发生异常),正常心脏搏动的起源部位应该是窦房结,由窦房结的异常激动产生的心律失常主要有心动过速、心动过缓、心律不齐以及停搏。判断得出心律失常的现象,依据现象判定心脏起搏器需要提供的刺激电压u o 的幅值大小和导通刺激时间t tot。其中刺激电压u o 的持续时间为导通刺激时间t totIn addition, arrhythmia (referring to any abnormality in the origin, frequency, rhythm, conduction, etc.) of the heart beat is judged by the electrocardiogram. The origin of the normal heart beat should be the sinoatrial node, and the heart rhythm produced by the abnormal excitation of the sinus node Arrhythmia mainly includes tachycardia, bradycardia, arrhythmia and asystole. The phenomenon of arrhythmia is determined, and the amplitude of the stimulation voltage u o and the conduction stimulation time t tot that the cardiac pacemaker needs to provide are determined according to the phenomenon. The duration of the stimulation voltage u o is the conduction stimulation time t tot .

本发明的工作原理是:无线心电传感器25采集使用者的心电信号,信号检测滤波电路1利用其内的运算放大器将微弱的心电信号放大、滤波、电压抬升最终生成心电模拟信号的波形;A/D转换电路3将心电模拟信号波形转换成数字信号送到数据处理分析电路4进行分析处理,由疲劳程度判断电路5根据心电信号的处理结果判断心脏的状态,输出控制电路6控制非接触供电原边电路7,由非接触供电原边线圈13对非接触供电副边线圈14传递能量,体内能量接收装置11整流滤波后由电极对心脏实施起搏刺激。 The working principle of the present invention is: the wireless ECG sensor 25 collects the user's ECG signal, and the signal detection filter circuit 1 utilizes an operational amplifier therein to amplify, filter, and raise the weak ECG signal to finally generate an ECG analog signal Waveform; the A/D conversion circuit 3 converts the ECG analog signal waveform into a digital signal and sends it to the data processing and analysis circuit 4 for analysis and processing, and the fatigue degree judgment circuit 5 judges the state of the heart according to the processing result of the ECG signal, and outputs the control circuit 6 Control the non-contact power supply primary circuit 7, the non-contact power supply primary coil 13 transmits energy to the non-contact power supply secondary coil 14, and the internal energy receiving device 11 rectifies and filters the heart through electrodes to perform pacing stimulation.

本发明可以通过三轴陀螺仪2实现心脏起搏器的主动起搏。当患者突然站立、跑步等运动状态下,心脏供血量暂时未表现出不足的状态,如果仅仅采用被动检测心电信号的方法,心脏起搏器的刺激信号强度在几秒钟内难以达到运动需要,患者可能会出现心慌气短甚至心脏跳动异常的极端情况。本发明采用三轴陀螺仪2同时测定三维空间三个坐标轴6个方向的位置、移动轨迹和加速度,将三轴陀螺仪2得到的信号送到数据处理和分析电路4处理。当检测到身体移动状况出现,立即加强心脏起搏刺激信号,即增大刺激的电压幅值并延长心电脉冲的导通刺激时间t tot。这种主动判断人体运动状态的方法可在1秒钟以内迅速刺激心脏功能,可以防止因为患者突然起床或突然由坐立到站立造成的脑供血不足甚至猝死的情况出现。 The present invention can realize the active pacing of the cardiac pacemaker through the three-axis gyroscope 2 . When the patient is in a state of exercise such as standing suddenly, running, etc., the blood supply to the heart does not appear to be insufficient for the time being. If only the method of passively detecting the ECG signal is used, the stimulation signal strength of the cardiac pacemaker is difficult to reach the level of the exercise within a few seconds. If necessary, the patient may experience extreme cases of palpitation, shortness of breath and even abnormal heartbeat. The present invention uses the three-axis gyroscope 2 to simultaneously measure the positions, moving tracks and accelerations of three coordinate axes in three-dimensional space in six directions, and sends the signals obtained by the three-axis gyroscope 2 to the data processing and analysis circuit 4 for processing. When the body movement is detected, the cardiac pacing stimulation signal is immediately strengthened, that is, the voltage amplitude of the stimulation is increased and the conduction stimulation time t tot of the electrocardiographic pulse is prolonged. This method of actively judging the state of human body movement can quickly stimulate the heart function within 1 second, and can prevent insufficient cerebral blood supply or even sudden death caused by the patient getting up suddenly or suddenly changing from sitting to standing.

本发明的电路电压波形如图6所示。非接触供电原边电路7由蓄电池9供电。通过外置起搏器电路27检测蓄电池9供给非接触供电原边电路7的端电压u i 和电流i i ,得到功率P i =u i ×i i 。根据电路结构得出非接触电路的传输效率近似值η,正电极15和负电极16两端负载为心脏电阻,可以等效为电阻R eq,该电阻在正电极15和负电极16安装时直接测定得到,则P i =u i ×i i =u o 2 /R eq,由此可以确定两个电极之间的电压u o 的幅值大小,电极之间的电压u o 幅值控制在1~5V之间。本发明体内能量接收装置11不需要直接检测心脏电极两侧电压,也不需要加装与外置起搏器电路27相匹配的通信电路,与以往的内置双腔起搏器相比,体内能量接收装置11的体积减小到原来的1/4以下,厚度减小到原来的1/3以下,体内能量接收装置11植入后能够永久工作不需更换。 The circuit voltage waveform of the present invention is shown in FIG. 6 . The non-contact power supply primary side circuit 7 is powered by a storage battery 9 . The terminal voltage u i and current i i supplied by the storage battery 9 to the non-contact power supply primary circuit 7 are detected by the external pacemaker circuit 27 to obtain power P i = u i × i i . According to the circuit structure, the approximate value of the transmission efficiency η of the non-contact circuit is obtained. The load at both ends of the positive electrode 15 and the negative electrode 16 is the heart resistance, which can be equivalent to the resistance Req , which is directly measured when the positive electrode 15 and the negative electrode 16 are installed. obtained, then P i = u i × i i = u o 2 / R eq , thus the amplitude of the voltage u o between the two electrodes can be determined, and the amplitude of the voltage u o between the electrodes is controlled within 1~ between 5V. The energy receiving device 11 in the body of the present invention does not need to directly detect the voltage on both sides of the heart electrode, and does not need to install a communication circuit that matches the external pacemaker circuit 27. Compared with the previous built-in dual-chamber pacemaker, the energy in the body The volume of the receiving device 11 is reduced to less than 1/4 of the original, and the thickness is reduced to less than 1/3 of the original. After implanted, the energy receiving device 11 in the body can work permanently without replacement.

非接触供电原边电路7选用全桥带变压器隔离的DC-DC变换器电路,由单相全桥电路将直流电转换成高频交流电(65kHz)。u dr1u dr2为驱动全桥电路驱动信号波形。u p为非接触供电原边线圈13两端的电压波形。因此,驱动全桥电路驱动信号波形的脉冲宽度与周期时间的比值称为占空比t on。电极输出电压的持续时间即一次心电脉冲的导通刺激时间t tot表示非接触供电电路从启动供电到切断非接触供电电路供电的总时间,t tot通常为10ms~100ms。输出控制电路6通过控制非接触供电原边电路7的开关器件的占空比t on以改变电极的输出电压,输出控制电路6通过判断和控制非接触供电原边电路7总的供电时间,以改变导通刺激时间t totThe non-contact power supply primary side circuit 7 selects a full-bridge DC-DC converter circuit with transformer isolation, and converts direct current into high-frequency alternating current (65kHz) by a single-phase full-bridge circuit. u dr1 and u dr2 are driving signal waveforms for driving the full bridge circuit. u p is the voltage waveform at both ends of the primary coil 13 for non-contact power supply. Therefore, the ratio of the pulse width of the driving signal waveform driving the full-bridge circuit to the cycle time is called the duty cycle t on . The duration of the electrode output voltage, that is, the on-stimulation time t tot of an ECG pulse, represents the total time from the start of the non-contact power supply circuit to the cut-off of the power supply of the non-contact power supply circuit, and t tot is usually 10ms~100ms. The output control circuit 6 changes the output voltage of the electrode by controlling the duty cycle t on of the switching device of the primary side circuit 7 of the non-contact power supply, and the output control circuit 6 judges and controls the total power supply time of the primary side circuit 7 of the non-contact power supply, so as to Change the on-stimulus time t tot .

疲劳程度判断电路5判断心脏疲劳的方法是:测量心电信号波形的RR波峰(两个峰值R之间)的时间差,计算心率的变异特性,若RR波峰间期的时间大于正常的时间范围(一般取1秒)则判定为疲劳。判断状态可分为两种情况:如果人体处于心脏疲劳状态则可判定供血量不足以满足身体功能的需要,要启动起搏器;反之,人体疲劳程度较小,关闭起搏器或使之工作在微弱刺激状态。 The method for judging heart fatigue by the fatigue degree judging circuit 5 is: measure the time difference between the RR peaks (between two peaks R) of the ECG signal waveform, and calculate the variation characteristics of the heart rate, if the time between the RR peaks is greater than the normal time range ( Generally take 1 second) is judged as fatigue. Judging the state can be divided into two situations: if the human body is in a state of heart fatigue, it can be determined that the blood supply is not enough to meet the needs of body functions, and the pacemaker should be activated; otherwise, the human body is less fatigued, and the pacemaker should be turned off or activated Work in a weakly stimulated state.

疲劳程度判断电路5判断的人体疲劳程度传送至输出控制电路6,当人体疲劳时,输出控制电路6向非接触供电原边电路7输送控制电压,对心脏进行刺激。疲劳程度越大,增大占空比t on,刺激的电压幅值就越大,同时增大心电脉冲的导通刺激时间t tot。疲劳程度较小,减小占空比t on,刺激的电压幅值就减小,同时缩短心电脉冲的导通刺激时间t tot;如果人体处于休息或睡眠状态,心跳平稳,则不对其进行刺激。 The degree of human fatigue judged by the fatigue degree judging circuit 5 is sent to the output control circuit 6. When the human body is tired, the output control circuit 6 sends a control voltage to the non-contact power supply primary circuit 7 to stimulate the heart. The greater the degree of fatigue, the greater the duty cycle t on , the greater the voltage amplitude of the stimulation, and at the same time increase the on-stimulation time t tot of the ECG pulse. If the degree of fatigue is small, reduce the duty cycle t on , the voltage amplitude of the stimulation will decrease, and at the same time shorten the conduction stimulation time t tot of the ECG pulse; if the human body is resting or sleeping and the heartbeat is stable, it will not Stimulate.

以上所述,仅为本发明较佳的具体实施方式,但本发明的保护范围并不局限于此,任何熟悉本技术领域的技术人员在本发明揭露的技术范围内,可轻易想到的变化或替换,都应涵盖在本发明的保护范围之内。 The above is only a preferred embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any person skilled in the art can easily conceive of changes or modifications within the technical scope disclosed in the present invention. Replacement should be covered within the protection scope of the present invention.

Claims (10)

1.一种具有非接触供电功能的心脏起搏器,其特征在于,包括蓄电池(9)、外置起搏器电路(27)和体内能量接收装置(11),蓄电池(9)与外置起搏器电路(27)相连接,外置起搏器电路(27)外端设有无线心电传感器(25),无线心电传感器(25)安装在体外心脏处,体内能量接收装置(11)设置在左肩皮肤内,外置起搏器电路(27)与体内能量接收装置(11)通过电磁耦合相连接,体内能量接收装置(11)通过电极与心脏相连接。 1. A cardiac pacemaker with non-contact power supply function, characterized in that it includes a battery (9), an external pacemaker circuit (27) and an internal energy receiving device (11), the battery (9) and the external The pacemaker circuit (27) is connected, the external pacemaker circuit (27) is provided with a wireless ECG sensor (25), the wireless ECG sensor (25) is installed at the heart outside the body, and the energy receiving device (11 ) is set in the skin of the left shoulder, the external pacemaker circuit (27) is connected with the energy receiving device (11) in the body through electromagnetic coupling, and the energy receiving device (11) in the body is connected with the heart through electrodes. 2.根据权利要求1所述的具有非接触供电功能的心脏起搏器,其特征在于,所述体内能量接收装置(11)包括非接触供电副边线圈(14)、整流电路(8)、滤波电路(17)和电极接口(10),非接触供电副边线圈(14)通过电磁耦合与非接触供电原边线圈(13)相连接,非接触供电副边线圈(14)与整流电路(8)相连接,整流电路(8)与滤波电路(17)相连接,滤波电路(17)与电极接口(10)相连接,电极接口(10)与电极相连接。 2. The cardiac pacemaker with non-contact power supply function according to claim 1, characterized in that, the internal energy receiving device (11) includes a non-contact power supply secondary coil (14), a rectifier circuit (8), The filter circuit (17) and the electrode interface (10), the non-contact power supply secondary coil (14) is connected to the non-contact power supply primary coil (13) through electromagnetic coupling, the non-contact power supply secondary coil (14) is connected to the rectifier circuit ( 8) are connected to each other, the rectifier circuit (8) is connected to the filter circuit (17), the filter circuit (17) is connected to the electrode interface (10), and the electrode interface (10) is connected to the electrode. 3.根据权利要求1或2所述的具有非接触供电功能的心脏起搏器,其特征在于,所述外置起搏器电路(27)包括信号检测滤波电路(1)、控制电路(12)、非接触供电原边电路(7)和非接触供电原边线圈(13),无线心电传感器(25)与信号检测滤波电路(1)相连接,信号检测滤波电路(1)与控制电路(12)相连接,控制电路(12)与非接触供电原边电路(7)相连接,非接触供电原边电路(7)与非接触供电原边线圈(13)相连接。 3. The cardiac pacemaker with non-contact power supply function according to claim 1 or 2, characterized in that the external pacemaker circuit (27) includes a signal detection filter circuit (1), a control circuit (12 ), the non-contact power supply primary circuit (7) and the non-contact power supply primary coil (13), the wireless ECG sensor (25) is connected with the signal detection filter circuit (1), and the signal detection filter circuit (1) is connected with the control circuit (12) are connected, the control circuit (12) is connected with the non-contact power supply primary circuit (7), and the non-contact power supply primary circuit (7) is connected with the non-contact power supply primary coil (13). 4.根据权利要求3所述的具有非接触供电功能的心脏起搏器,其特征在于,所述控制电路(12)包括三轴陀螺仪(2)、A/D转换电路(3)、数据处理分析电路(4)、疲劳程度判断电路(5)和输出控制电路(6),A/D转换电路(3)与信号检测滤波电路(1)相连接,三轴陀螺仪(2)、A/D转换电路(3)分别与数据处理分析电路(4)相连接,数据处理分析电路(4)与疲劳程度判断电路(5)相连接,疲劳程度判断电路(5)与输出控制电路(6)相连接,输出控制电路(6)与非接触供电原边电路(7)相连接。 4. The cardiac pacemaker with non-contact power supply function according to claim 3, characterized in that, the control circuit (12) includes a three-axis gyroscope (2), an A/D conversion circuit (3), a data Processing analysis circuit (4), fatigue degree judgment circuit (5) and output control circuit (6), A/D conversion circuit (3) is connected with signal detection filter circuit (1), three-axis gyroscope (2), A The /D conversion circuit (3) is respectively connected with the data processing and analysis circuit (4), the data processing and analysis circuit (4) is connected with the fatigue degree judgment circuit (5), and the fatigue degree judgment circuit (5) is connected with the output control circuit (6) ), and the output control circuit (6) is connected with the non-contact power supply primary side circuit (7). 5.根据权利要求3所述的具有非接触供电功能的心脏起搏器,其特征在于,所述无线心电传感器(25)以可穿戴方式安装在体外心脏附近的围胸服装内,非接触供电原边线圈(13)和非接触供电副边线圈(14)平行安装在左肩下,非接触供电原边线圈(13)和非接触供电副边线圈(14)之间的距离在0.3~0.5cm之间,非接触供电原边线圈(13)和非接触供电副边线圈(14)以非接触方式传输磁场能量。 5. The cardiac pacemaker with non-contact power supply function according to claim 3, characterized in that, the wireless ECG sensor (25) is installed in a corset garment near the external heart in a wearable manner, non-contact The power supply primary coil (13) and the non-contact power supply secondary coil (14) are installed in parallel under the left shoulder, and the distance between the non-contact power supply primary coil (13) and the non-contact power supply secondary coil (14) is 0.3~0.5 cm, the non-contact power supply primary coil (13) and the non-contact power supply secondary coil (14) transmit magnetic field energy in a non-contact manner. 6.根据权利要求3所述的具有非接触供电功能的心脏起搏器,其特征在于,所述非接触供电副边线圈(14)是用细铜漆包线绕制而成的线圈,整流电路(8)和滤波电路(17)为贴片元件。 6. The cardiac pacemaker with non-contact power supply function according to claim 3, characterized in that, the non-contact power supply secondary coil (14) is a coil wound with thin copper enameled wire, and the rectifier circuit ( 8) and filter circuit (17) are chip components. 7.根据权利要求4所述的具有非接触供电功能的心脏起搏器,其特征在于,其工作原理是:无线心电传感器(25)采集使用者的心电信号,信号检测滤波电路(1)利用其内的运算放大器将微弱的心电信号放大、滤波、电压抬升最终生成心电模拟信号的波形;A/D转换电路(3)将心电模拟信号波形转换成数字信号送到数据处理分析电路(4)进行分析处理,由疲劳程度判断电路(5)根据心电信号的处理结果判断心脏的状态,输出控制电路(6)控制非接触供电原边电路(7)的开关器件的占空比t on,由非接触供电原边线圈(13)对非接触供电副边线圈(14)传递能量,体内能量接收装置(11)整流滤波后由电极对心脏实施起搏刺激。 7. The cardiac pacemaker with non-contact power supply function according to claim 4, characterized in that, its working principle is: the wireless ECG sensor (25) collects the user's ECG signal, and the signal detection filter circuit (1 ) uses the operational amplifier inside to amplify, filter, and raise the voltage of the weak ECG signal to finally generate the waveform of the ECG analog signal; the A/D conversion circuit (3) converts the waveform of the ECG analog signal into a digital signal and sends it to data processing The analysis circuit (4) performs analysis and processing, the fatigue degree judgment circuit (5) judges the state of the heart according to the processing result of the ECG signal, and the output control circuit (6) controls the occupation of the switching device of the non-contact power supply primary side circuit (7). In the empty ratio t on , the non-contact power supply primary coil (13) transmits energy to the non-contact power supply secondary coil (14), and the internal energy receiving device (11) rectifies and filters the heart through electrodes to perform pacing stimulation. 8.根据权利要求7所述的具有非接触供电功能的心脏起搏器,其特征在于,所述疲劳程度判断电路(5)判断心脏疲劳的方法:测量心电信号波形RR波峰间的时间差,计算心率的变异特性,若RR波峰间期的时间大于正常的时间范围则判定为疲劳。 8. The cardiac pacemaker with non-contact power supply function according to claim 7, characterized in that, the fatigue degree judging circuit (5) judges the method of heart fatigue: measuring the time difference between the peaks of the ECG waveform RR, Calculate the variability characteristics of heart rate, and if the time between RR peaks is greater than the normal time range, it is judged as fatigue. 9.根据权利要求7所述的具有非接触供电功能的心脏起搏器,其特征在于,所述输出控制电路(6)通过控制非接触供电原边电路(7)开关器件的占空比t on改变电极的输出电压u o ,输出控制电路(6)通过判断和控制非接触供电原边电路(7)总的供电时间,以改变电极输出电压u o 的持续时间,持续时间是一次心电脉冲的导通刺激时间t tot9. The cardiac pacemaker with non-contact power supply function according to claim 7, characterized in that, the output control circuit (6) controls the duty cycle t of the switching device of the non-contact power supply primary side circuit (7) on changes the output voltage u o of the electrode, the output control circuit (6) judges and controls the total power supply time of the non-contact power supply primary side circuit (7) to change the duration of the electrode output voltage u o , the duration is one ECG The on-stimulation time t tot of the pulse. 10.根据权利要求7所述的具有非接触供电功能的心脏起搏器,其特征在于,所述三轴陀螺仪(2)测定三维空间三个坐标轴6个方向的位置、移动轨迹和加速度,将得到的信号送到数据处理和分析电路(4)处理进行分析处理,当检测到身体移动时,输出控制电路(6)立即加强心脏起搏刺激信号,增大刺激的电压幅值并延长心电脉冲的导通刺激时间t tot10. The cardiac pacemaker with non-contact power supply function according to claim 7, characterized in that the three-axis gyroscope (2) measures the position, movement trajectory and acceleration in six directions of three coordinate axes in three-dimensional space , send the obtained signal to the data processing and analysis circuit (4) for analysis and processing, when the body movement is detected, the output control circuit (6) immediately strengthens the cardiac pacing stimulation signal, increases the voltage amplitude of the stimulation and extends The conduction stimulation time t tot of the electrocardiographic pulse.
CN201610069613.XA 2016-02-02 2016-02-02 Pacemaker with contactless power supply Active CN105597233B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610069613.XA CN105597233B (en) 2016-02-02 2016-02-02 Pacemaker with contactless power supply

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610069613.XA CN105597233B (en) 2016-02-02 2016-02-02 Pacemaker with contactless power supply

Publications (2)

Publication Number Publication Date
CN105597233A true CN105597233A (en) 2016-05-25
CN105597233B CN105597233B (en) 2017-12-22

Family

ID=55977924

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610069613.XA Active CN105597233B (en) 2016-02-02 2016-02-02 Pacemaker with contactless power supply

Country Status (1)

Country Link
CN (1) CN105597233B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106073750A (en) * 2016-08-29 2016-11-09 廖晓莉 Ventricle blood supply abnormal detector and the indirect acquiring and processing method of heart pulse wave data
CN114983426A (en) * 2022-04-22 2022-09-02 清华大学 Electrophysiological signal wireless detection method and system based on electromagnetic coupling principle
CN115153573A (en) * 2022-07-04 2022-10-11 深圳原子半导体科技有限公司 ECG acquisition circuit, device and electrocardiograph

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102895734A (en) * 2012-10-30 2013-01-30 河南工程学院 Two-path dual-active non-contact power system for cardiac pacemaker
US20140100622A1 (en) * 2012-10-10 2014-04-10 Physio-Control, Inc. External defibrillation with automatic post-shock anti-tachycardia (apsat) pacing
US20140343349A1 (en) * 2013-05-20 2014-11-20 Mark Klingler Borsody Coordinating emergency treatment of cardiac dysfunction and non-cardiac neural dysfunction
CN205307613U (en) * 2016-02-02 2016-06-15 河南工程学院 Cardiac pacemaker with non -contact power supply function

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140100622A1 (en) * 2012-10-10 2014-04-10 Physio-Control, Inc. External defibrillation with automatic post-shock anti-tachycardia (apsat) pacing
CN102895734A (en) * 2012-10-30 2013-01-30 河南工程学院 Two-path dual-active non-contact power system for cardiac pacemaker
US20140343349A1 (en) * 2013-05-20 2014-11-20 Mark Klingler Borsody Coordinating emergency treatment of cardiac dysfunction and non-cardiac neural dysfunction
CN205307613U (en) * 2016-02-02 2016-06-15 河南工程学院 Cardiac pacemaker with non -contact power supply function

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106073750A (en) * 2016-08-29 2016-11-09 廖晓莉 Ventricle blood supply abnormal detector and the indirect acquiring and processing method of heart pulse wave data
CN106073750B (en) * 2016-08-29 2023-07-28 廖晓莉 Ventricular blood supply abnormality detection device and indirect collection processing method of heart pulse wave data
CN114983426A (en) * 2022-04-22 2022-09-02 清华大学 Electrophysiological signal wireless detection method and system based on electromagnetic coupling principle
CN115153573A (en) * 2022-07-04 2022-10-11 深圳原子半导体科技有限公司 ECG acquisition circuit, device and electrocardiograph

Also Published As

Publication number Publication date
CN105597233B (en) 2017-12-22

Similar Documents

Publication Publication Date Title
CN103118741B (en) Wireless heart is beaten sensing
US10709892B2 (en) Temporal configuration of a motion sensor in an implantable medical device
US7200440B2 (en) Cardiac cycle synchronized sampling of impedance signal
US20130218219A1 (en) Pulse Parameters And Electrode Conffigurations For Reducing Patient Discomfort From Defibrillation
JP6836833B2 (en) Medical monitoring and treatment equipment with external pacing
US6449509B1 (en) Implantable stimulation device having synchronous sampling for a respiration sensor
US7925348B1 (en) Extra-cardiac impedance based hemodynamic assessment method and system
CN112312962A (en) Multi-axis coil for implantable medical device
US8571641B2 (en) Apparatus and method for processing physiological measurement values
US8792970B2 (en) System and method for analyzing an impedance course
US20230038471A1 (en) Method and Apparatus for Monitoring a Patient
US20170056669A1 (en) Systems and methods for cardio-respiratory pacing
US9538922B2 (en) Monitoring an interval within the cardiac cycle
EP2731499B1 (en) Apparatuses to predict ventricular remodeling
CN105597233B (en) Pacemaker with contactless power supply
JP5739457B2 (en) Detection of hemodynamic stability during arrhythmia using a respiration sensor
US7003348B1 (en) Monitoring cardiac geometry for diagnostics and therapy
CN205307613U (en) Cardiac pacemaker with non -contact power supply function
CN106938121A (en) External defibrillation pacing system
CN112584895B (en) Heart Device System
JP2024502077A (en) Cardiac pacing threshold acquisition method, pacing control method and device, medical device
JP2019506954A (en) Cardiac defibrillation pacing method and system
CN111701143A (en) Cardiovascular disease first aid is with intelligent defibrillator based on electrocardio data
CN116919803A (en) A smart vest that works together for cardiopulmonary resuscitation and defibrillation
US20180008197A1 (en) Minute volume sensor optimization using quadripolar leads

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
CB03 Change of inventor or designer information
CB03 Change of inventor or designer information

Inventor after: Zhou Chenghu

Inventor after: Zhu Yongbiao

Inventor after: Ma Chuxin

Inventor after: Li Baisong

Inventor after: Yuan Xun

Inventor after: Xing Weiwei

Inventor after: Liu Lei

Inventor after: Jia Lidong

Inventor after: Wu Hongbo

Inventor after: Wu Tao

Inventor after: Zhang Kun

Inventor after: Li Xiaokui

Inventor after: Chen Bingyang

Inventor after: Wang Zhentao

Inventor after: Wang Jing

Inventor after: Luo Jiming

Inventor after: Chen Chaoyang

Inventor after: Zhang Qiuhui

Inventor after: Jia Zhenzhen

Inventor after: Zhang Feifei

Inventor after: Xu Fengkuan

Inventor after: Zhou Jianwei

Inventor before: Zhou Chenghu

Inventor before: Li Baisong

Inventor before: Yuan Xun

Inventor before: Xing Weiwei

Inventor before: Liu Lei

Inventor before: Jia Lidong

Inventor before: Wu Hongbo

Inventor before: Wu Tao

Inventor before: Zhang Kun

Inventor before: Chen Bingyang

Inventor before: Wang Zhentao

Inventor before: Chen Chaoyang

Inventor before: Wang Jing

Inventor before: Zhang Qiuhui

Inventor before: Jia Zhenzhen

Inventor before: Zhang Feifei

Inventor before: Xu Fengkuan

Inventor before: Zhou Jianwei

Inventor before: Zhu Yongbiao

Inventor before: Ma Chuxin

GR01 Patent grant
GR01 Patent grant
EE01 Entry into force of recordation of patent licensing contract
EE01 Entry into force of recordation of patent licensing contract

Application publication date: 20160525

Assignee: Henan New Industrial Technology Research Institute Co.,Ltd.

Assignor: HENAN INSTITUTE OF ENGINEERING

Contract record no.: X2024980026392

Denomination of invention: Cardiac pacemaker with non-contact power supply function

Granted publication date: 20171222

License type: Common License

Record date: 20241120