CN105596210B - A kind of automatic detection formula deoxygenation blood bag preparation facilities and method - Google Patents
A kind of automatic detection formula deoxygenation blood bag preparation facilities and method Download PDFInfo
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- CN105596210B CN105596210B CN201610003530.0A CN201610003530A CN105596210B CN 105596210 B CN105596210 B CN 105596210B CN 201610003530 A CN201610003530 A CN 201610003530A CN 105596210 B CN105596210 B CN 105596210B
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- blood bag
- blood
- solenoid valve
- clamping device
- automatic detection
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- 239000008280 blood Substances 0.000 title claims abstract description 131
- 210000004369 blood Anatomy 0.000 title claims abstract description 131
- 238000006392 deoxygenation reaction Methods 0.000 title claims abstract description 29
- 238000001514 detection method Methods 0.000 title claims abstract description 27
- 238000002360 preparation method Methods 0.000 title claims abstract description 27
- 238000000034 method Methods 0.000 title claims abstract description 18
- 239000001301 oxygen Substances 0.000 claims abstract description 34
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 34
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 33
- 239000007788 liquid Substances 0.000 claims description 22
- 239000007789 gas Substances 0.000 claims description 15
- 239000012943 hotmelt Substances 0.000 claims description 11
- 239000001307 helium Substances 0.000 claims description 5
- 229910052734 helium Inorganic materials 0.000 claims description 5
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 claims description 5
- 238000002844 melting Methods 0.000 claims description 5
- 239000011261 inert gas Substances 0.000 claims description 4
- 230000000694 effects Effects 0.000 abstract description 4
- 230000015556 catabolic process Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000004064 recycling Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B31/00—Packaging articles or materials under special atmospheric or gaseous conditions; Adding propellants to aerosol containers
- B65B31/04—Evacuating, pressurising or gasifying filled containers or wrappers by means of nozzles through which air or other gas, e.g. an inert gas, is withdrawn or supplied
- B65B31/041—Evacuating, pressurising or gasifying filled containers or wrappers by means of nozzles through which air or other gas, e.g. an inert gas, is withdrawn or supplied the nozzles acting from above on containers or wrappers open at their top
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/10—Bag-type containers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
- G01F23/00—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/0004—Gaseous mixtures, e.g. polluted air
- G01N33/0009—General constructional details of gas analysers, e.g. portable test equipment
- G01N33/0027—General constructional details of gas analysers, e.g. portable test equipment concerning the detector
- G01N33/0036—General constructional details of gas analysers, e.g. portable test equipment concerning the detector specially adapted to detect a particular component
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Analytical Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Mechanical Engineering (AREA)
- Combustion & Propulsion (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Fluid Mechanics (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- External Artificial Organs (AREA)
Abstract
The present invention relates to blood bag storage blood field more particularly to a kind of automatic detection formula deoxygenation blood bag preparation facilities and methods.The technical problem to be solved in the present invention is to provide the automatic detection formula deoxygenation blood bag preparation facilities and method of a kind of simple and effective that can be detected oxygen content automatically and feed back.A kind of automatic detection formula deoxygenation blood bag preparation facilities including organic frame, clamping device, inlet channel, outlet passageway, is equipped with clamping device on front side of rack, clamping device upper left is equipped with inlet channel, and clamping device upper right is equipped with outlet passageway.A kind of automatic detection formula deoxygenation blood bag preparation method, this method carry out on detection formula deoxygenation blood bag preparation facilities automatically, and by step a step e, existing oxygen in blood bag is removed.By above-mentioned automatic detection formula deoxygenation blood bag preparation facilities and method, the blood bag deoxygenation that can detect oxygen content and the simple and effective fed back automatically is achieved the effect that, has had the advantages that improve blood quality, extends the blood storage time.
Description
Technical field
The present invention relates to blood bag storage blood field more particularly to a kind of automatic detection formula deoxygenation blood bag preparation facilities and methods.
Background technology
Blood bag as container important in blood transfer process, be widely used in blood collection, blood preseration, blood transportation,
The various aspects that blood uses carry the effect that can not be substituted during the recycling of blood, but are prepared under existing way
Blood bag bag in air can not be completely exhausted out, inside is containing a large amount of oxygen, the contacting blood oxygen in blood bag, the easy quilt of blood
Oxidation deterioration directly results in the degradation of blood, shortens the holding time of blood, is unfavorable for the storage and use of blood.
The content of the invention
(1) technical problems to be solved
The present invention can cause blood by oxygen in order to which gas is overcome in the blood bag produced under existing way bag to contain a large amount of oxygen
Change the shortcomings that rotten, the holding time is short, the technical problem to be solved in the present invention is to provide a kind of oxygen content and anti-of detecting automatically
The automatic detection formula deoxygenation blood bag preparation facilities and method of the simple and effective of feedback.
(2) technical solution
In order to solve the above technical problem, the present invention provides such a automatic detection formula deoxygenation blood bag preparation facilities,
Including organic frame, clamping device, inlet channel, outlet passageway, clamping device is equipped on front side of rack, clamping device upper left is set
There is inlet channel, clamping device upper right is equipped with outlet passageway.
Preferably, it is equipped with ink jet numbering machine in the clamping device right.
Preferably, conveyer belt is equipped on rear side of the clamping device.
Preferably, boss is equipped on rear side of the conveyer belt.
Preferably, liquid level sensor is equipped on the boss.
Preferably, solenoid valve I is equipped on the inlet channel.
Preferably, solenoid valve II is equipped on the outlet passageway.
Preferably, oxygen analyser is equipped on the outlet passageway, and oxygen analyser is located at II right side of solenoid valve.
Preferably, it is equipped with container case in the rack right end.
Preferably, hot melt collet is equipped with above the clamping device.
The present invention provides such a automatic detection formula deoxygenation blood bag preparation method, this method utilizes above-mentioned one kind certainly
Dynamic detection formula deoxygenation blood bag preparation facilities carries out, and this method step is as follows：
A. the blood bag equipped with blood being positioned at clamping device, the left blood transfusion port on blood bag top is connected with inlet channel,
Right blood transfusion port is connected with outlet passageway, and solenoid valve I is closed, and solenoid valve II is opened；
B. clamping device squeezes blood bag, and air is discharged from outlet passageway, and the liquid level of blood rises in blood bag, works as level sensing
When device senses that the liquid level of blood is risen to away from left and right blood transfusion port 0.5-1cm, solenoid valve II is closed, and solenoid valve I is opened；
C. inlet channel starts to be filled with inert gas, starts after inflating 4-6s, and solenoid valve II is opened, and continues to inflate, when
When oxygen analyser detects that the content of oxygen in discharge gas is less than 0.5%-1.5%, stop supply, solenoid valve I and solenoid valve II
It simultaneously closes off；
D. collet will be heated to clamp the left and right blood transfusion port of blood bag and carry out hot-melting sealed processing, then, conveyer belt is by blood bag
It is sent at ink jet numbering machine；
E. ink jet numbering machine carries out coding in blood bag, and after coding mark is completed, blood bag is sent to container case by conveyer belt
In.
Preferably, in step c, the inert gas being filled with is helium.
Preferably, in step c, inner gas pressure 140-150kpa.
Preferably, in step c, when oxygen analyser detects that oxygen content is less than 1% in discharge gas, supply is stopped.
Preferably, in step d or e, the speed of conveyer belt is 0.1-0.2m/s.
The ink jet numbering machine, conveyer belt, liquid level sensor, solenoid valve, oxygen analyser, hot melt collet are the prior art, of the invention
No longer it is explained in detail.
(3) advantageous effect
A kind of automatic detection formula deoxygenation blood bag preparation facilities of the present invention has reached can detect oxygen content and anti-automatically
The effect of the blood bag deoxygenation of the simple and effective of feedback, a kind of automatic detection formula deoxygenation blood bag preparation method of the present invention, which has, to be carried
High blood quality extends the advantages of blood storage time.
Description of the drawings
Fig. 1 is the structural diagram of the present invention.
Mark in attached drawing for：1- racks, 2- clamping devices, 3- ink jet numbering machines, 4- conveyer belts, 5- boss, 6- solenoid valves I,
7- inlet channels, 8- outlet passageways, 9- solenoid valves II, 10- oxygen analysers, 11- liquid level sensors, 12- hot melt collets, 13- blood bags,
14- blood, 15- container cases.
Specific embodiment
The present invention is further illustrated with reference to the accompanying drawings and examples.
Embodiment 1
A kind of automatic detection formula deoxygenation blood bag preparation facilities, as shown in Figure 1, leading to including organic frame 1, clamping device 2, air inlet
Road 7, outlet passageway 8,1 front side of rack are equipped with clamping device 2, and 2 upper left of clamping device is equipped with inlet channel 7, clamping device 2
Upper right is equipped with outlet passageway 8, and 2 right of clamping device is equipped with ink jet numbering machine 3, and 2 inside of clamping device is equipped with conveyer belt 4,
4 inside of conveyer belt is equipped with boss 5, and boss 5 is equipped with liquid level sensor 11, and the inlet channel 7 is equipped with solenoid valve I 6, described
Outlet passageway 8 is equipped with solenoid valve II 9, and outlet passageway 8 is equipped with oxygen analyser 10, and the solenoid valve II 9 is located at 10 left side of oxygen analyser, institute
1 right end of rack is stated equipped with container case 15,2 top of clamping device is equipped with hot melt collet 12.
Embodiment 2
A kind of automatic detection formula deoxygenation blood bag preparation method, this method are enterprising in detection formula deoxygenation blood bag preparation facilities automatically
Row, the device is as shown in Figure 1, including organic frame 1, clamping device 2, ink jet numbering machine 3, conveyer belt 4, boss 5, solenoid valve I 6, air inlet
Passage 7, outlet passageway 8, solenoid valve II 9, oxygen analyser 10, liquid level sensor 11, hot melt collet 12, container case 15, this method step
It is rapid as follows：
A. the blood bag 13 equipped with blood 14 is positioned at clamping device 2, the left blood transfusion port on 13 top of blood bag leads to air inlet
Road 7 is connected, and right blood transfusion port is connected with outlet passageway 8, and solenoid valve I 6 is closed, and solenoid valve II 9 is opened；
B. clamping device 2 squeezes blood bag 13, and air is discharged from outlet passageway 8, and the liquid level of blood 14 rises in blood bag 13, when
When liquid level sensor 11 senses that the liquid level of blood 14 is risen to away from left and right blood transfusion port 0.5cm, solenoid valve II 9 is closed, solenoid valve I
6 open；
C. inlet channel 7 starts to be filled with helium, and inner gas pressure 150kpa starts after inflating 6s, and solenoid valve II 9 is opened,
And continue to inflate, when oxygen analyser 10 detects that the content of oxygen in discharge gas is less than 0.5%, stop supply, solenoid valve I 6
It is simultaneously closed off with solenoid valve II 9；
D. hot melt collet 12 is clamped into the left and right blood transfusion port of blood bag 13 and carries out hot-melting sealed processing, then, conveyer belt 4 will
Blood bag 13 is sent at ink jet numbering machine 3, and the speed of conveyer belt 4 is 0.1m/s；
E. ink jet numbering machine 3 carries out coding in blood bag 13, after coding mark is completed, is sent to blood bag 13 by conveyer belt 4
In container case 15, the speed of conveyer belt 4 is 0.1m/s.
Embodiment 3
A kind of automatic detection formula deoxygenation blood bag preparation method, this method are enterprising in detection formula deoxygenation blood bag preparation facilities automatically
Row, the device is as shown in Figure 1, including organic frame 1, clamping device 2, ink jet numbering machine 3, conveyer belt 4, boss 5, solenoid valve I 6, air inlet
Passage 7, outlet passageway 8, solenoid valve II 9, oxygen analyser 10, liquid level sensor 11, hot melt collet 12, container case 15, this method step
It is rapid as follows：
A. the blood bag 13 equipped with blood 14 is positioned at clamping device 2, the left blood transfusion port on 13 top of blood bag leads to air inlet
Road 7 is connected, and right blood transfusion port is connected with outlet passageway 8, and solenoid valve I 6 is closed, and solenoid valve II 9 is opened；
B. clamping device 2 squeezes blood bag 13, and air is discharged from outlet passageway 8, and the liquid level of blood 14 rises in blood bag 13, when
When liquid level sensor 11 senses that the liquid level of blood 14 is risen to away from left and right blood transfusion port 0.8cm, solenoid valve II 9 is closed, solenoid valve I
6 open；
C. inlet channel 7 starts to be filled with helium, and inner gas pressure 145kpa starts after inflating 5s, and solenoid valve II 9 is opened,
And continue to inflate, when oxygen analyser 10 detects that the content of oxygen in discharge gas is less than 1%, stop supply, I 6 He of solenoid valve
Solenoid valve II 9 simultaneously closes off；
D. hot melt collet 12 is clamped into the left and right blood transfusion port of blood bag 13 and carries out hot-melting sealed processing, then, conveyer belt 4 will
Blood bag 13 is sent at ink jet numbering machine 3, and the speed of conveyer belt 4 is 0.15m/s；
E. ink jet numbering machine 3 carries out coding in blood bag 13, after coding mark is completed, is sent to blood bag 13 by conveyer belt 4
In container case 15, the speed of conveyer belt 4 is 0.15m/s.
Embodiment 4
A kind of automatic detection formula deoxygenation blood bag preparation method, this method are enterprising in detection formula deoxygenation blood bag preparation facilities automatically
Row, the device is as shown in Figure 1, including organic frame 1, clamping device 2, ink jet numbering machine 3, conveyer belt 4, boss 5, solenoid valve I 6, air inlet
Passage 7, outlet passageway 8, solenoid valve II 9, oxygen analyser 10, liquid level sensor 11, hot melt collet 12, container case 15, this method step
It is rapid as follows：
A. the blood bag 13 equipped with blood 14 is positioned at clamping device 2, the left blood transfusion port on 13 top of blood bag leads to air inlet
Road 7 is connected, and right blood transfusion port is connected with outlet passageway 8, and solenoid valve I 6 is closed, and solenoid valve II 9 is opened；
B. clamping device 2 squeezes blood bag 13, and air is discharged from outlet passageway 8, and the liquid level of blood 14 rises in blood bag 13, when
When liquid level sensor 11 senses that the liquid level of blood 14 is risen to away from left and right blood transfusion port 1cm, solenoid valve II 9 is closed, solenoid valve I 6
It opens；
C. inlet channel 7 starts to be filled with helium, and inner gas pressure 140kpa starts after inflating 4s, and solenoid valve II 9 is opened,
And continue to inflate, when oxygen analyser 10 detects that the content of oxygen in discharge gas is less than 1.5%, stop supply, solenoid valve I 6
It is simultaneously closed off with solenoid valve II 9；
D. hot melt collet 12 is clamped into the left and right blood transfusion port of blood bag 13 and carries out hot-melting sealed processing, then, conveyer belt 4 will
Blood bag 13 is sent at ink jet numbering machine 3, and the speed of conveyer belt 4 is 0.2m/s；
E. ink jet numbering machine 3 carries out coding in blood bag 13, after coding mark is completed, is sent to blood bag 13 by conveyer belt 4
In container case 15, the speed of conveyer belt 4 is 0.2m/s.
Embodiment described above only expresses the preferred embodiment of the present invention, and description is more specific and detailed, but simultaneously
Cannot the limitation to the scope of the claims of the present invention therefore be interpreted as.It should be pointed out that for those of ordinary skill in the art
For, without departing from the inventive concept of the premise, several deformations can also be made, improves and substitutes, these belong to this hair
Bright protection domain.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.
Claims (4)
1. a kind of automatic detection formula deoxygenation blood bag preparation facilities, which is characterized in that including organic frame (1), clamping device (2), into
Gas passage (7), outlet passageway (8), rack (1) front side are equipped with clamping device (2), and clamping device (2) upper left is equipped with air inlet
Passage (7), clamping device (2) upper right are equipped with outlet passageway (8)；Clamping device (2) right is equipped with ink jet numbering machine (3),
Conveyer belt (4) is equipped on rear side of the clamping device (2), the inlet channel (7) is equipped with solenoid valve I (6), the outlet passageway
(8) it is equipped with solenoid valve II (9)；Boss (5) is equipped on rear side of the conveyer belt (4)；The boss (5) is equipped with liquid level sensor
(11)；The outlet passageway (8) is equipped with oxygen analyser (10), and oxygen analyser (10) is located on the right side of the solenoid valve II (9)；It is described
Hot melt collet (12) is equipped with above clamping device (2), rack (1) right end is equipped with container case (15).
2. a kind of automatic detection formula deoxygenation blood bag preparation method, which is characterized in that this method utilizes as described in claim 1 one
The automatic detection formula deoxygenation blood bag preparation facilities of kind carries out, and its step are as follows：
A. will be positioned over equipped with the blood bag (13) of blood (14) at clamping device (2), the left blood transfusion port on blood bag (13) top with into
Gas passage (7) is connected, and right blood transfusion port is connected with outlet passageway (8), and solenoid valve I (6) is closed, and solenoid valve II (9) is opened；
B. clamping device (2) squeezes blood bag (13), and air is discharged from outlet passageway (8), the liquid level of blood bag (13) interior blood (14)
Rise, when liquid level sensor (11) senses that the liquid level of blood (14) is risen to away from left and right blood transfusion port 0.5-1cm, solenoid valve II
(9) close, solenoid valve I (6) is opened；
C. inlet channel (7) starts to be filled with inert gas, and inner gas pressure 140-150kpa starts after inflating 4-6s, solenoid valve
II (9) are opened, and continue to inflate, when oxygen analyser (10) detects that the content of oxygen in discharge gas is less than 0.5%-1.5%,
Stop supply, solenoid valve I (6) and solenoid valve II (9) simultaneously close off；
D. collet (12) will be heated to clamp the left and right blood transfusion port of blood bag (13) and carry out hot-melting sealed processing, then, conveyer belt (4)
Blood bag (13) is sent at ink jet numbering machine (3)；
E. ink jet numbering machine (3) carries out coding in blood bag (13), after coding mark is completed, is passed blood bag (13) by conveyer belt (4)
It send into container case (15).
3. according to the automatic detection formula deoxygenation blood bag preparation method of one kind described in claim 2, which is characterized in that in step c, fill
The inert gas entered is helium, when the oxygen analyser (10) detects that oxygen content is less than 1% in discharge gas, stops supply.
4. according to the automatic detection formula deoxygenation blood bag preparation method of one kind described in claim 2, which is characterized in that in step d or e
In, the speed of conveyer belt (4) is 0.1-0.2m/s.
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| CN108955646B (en) * | 2018-05-15 | 2020-10-16 | 武汉理工大学 | Automatic detection device for steel rail welding seam center |
| CN113459593B (en) * | 2021-07-29 | 2022-11-22 | 山东中保康医疗器具有限公司 | Inflating method for producing disposable white blood cell removing plastic blood bag |
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