CN105581909A - Multi-dipping-type full-automatic enteric hollow capsule forming manufacturing production line - Google Patents

Multi-dipping-type full-automatic enteric hollow capsule forming manufacturing production line Download PDF

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Publication number
CN105581909A
CN105581909A CN201610103513.4A CN201610103513A CN105581909A CN 105581909 A CN105581909 A CN 105581909A CN 201610103513 A CN201610103513 A CN 201610103513A CN 105581909 A CN105581909 A CN 105581909A
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CN
China
Prior art keywords
dip
dipping
capsule
workbench
electric cabinet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610103513.4A
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Chinese (zh)
Inventor
陈光伦
张强
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CHONGQING HENGSHENG CAPSULES FOR MEDICINES Co Ltd
Original Assignee
CHONGQING HENGSHENG CAPSULES FOR MEDICINES Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CHONGQING HENGSHENG CAPSULES FOR MEDICINES Co Ltd filed Critical CHONGQING HENGSHENG CAPSULES FOR MEDICINES Co Ltd
Priority to CN201610103513.4A priority Critical patent/CN105581909A/en
Publication of CN105581909A publication Critical patent/CN105581909A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/077Manufacturing capsule shells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2200/00General characteristics or adaptations
    • A61J2200/40Heating or cooling means; Combinations thereof
    • A61J2200/42Heating means

Abstract

The invention provides a multi-dipping-type full-automatic enteric hollow capsule forming manufacturing production line. A heating device, a secondary dipping working table and a third-time dipping working table are installed on the original basis, and rod needles are made of special capsule mold alloy steel. The multi-dipping-type full-automatic enteric hollow capsule forming manufacturing production line has the advantages that gelatin liquid can keep the necessary temperature and melting degree, uniform gelatin liquid dipping can be conveniently achieved, the condition that the capsule walls are ununiform in thickness or even micropores are formed in the capsule walls can be avoided, and the gelatin dipping quality is improved; meanwhile, gelatin dipping can be performed on a capsule mold by three times, and capsule raw materials containing different ingredients or of the different weights are supplied by gelatin melting devices arranged on the different gelatin dipping working tables, so that enteric hollow capsules are appropriately melted at the different parts such as the esophagus, the stomach and the intestines to be suitable for digestion and absorption of the different parts; in addition, by adopting the rod needles made of the material obtained through the special raw material and a formula, demolding can be better performed on hollow capsule blanks formed after gelatin dipping, and the empty shell depression rate of the capsules is decreased.

Description

Dip in the full-automatic enteric hollow capsule moulding of formula manufacturing line more
Technical field
The present invention relates to Capsules production equipment manufacturing technology field, particularly the full-automatic enteric hollow capsule manufacturing line of a kind of formula of dipping in more.
Background technology
Capsules is one of the most frequently used pharmaceutic adjuvant, due to the raising of people's living standard and medical level, except medicine, also starts to use in a large number capsule at food and cosmetic industry, and the year sales volume of current domestic Capsules has exceeded 200,000,000,000.
Existing Capsules production method is first Capsules raw material to be put into glue pot stirs, colloidal sol, remove bubble, through dipping in glue, oven dry, cooling, the demoulding, cutting, fit, inspection, lettering, checking, weigh, pack, produce thereby complete Capsules again. Critical process is wherein exactly the moulding manufacture from glue to Capsules, although existing Capsules moulding manufacturing line is also full-automatic enteric hollow capsule production line, but be disposable glue and the drying forming of dipping in, due to the reason of glue itself, easily cause the cyst wall gage distortion of Capsules, in actual production, need to continue to dip in glue toward contact, continuing to dip in glue can only complete by craft.
But because manual completing dipped in glue and had following defect: 1 easy artificial pollution product, sanitary condition is unstable, and 2 workmans' qualification difference can make product quality situation unstable, and 3 labour costs are high, and production efficiency is low. Also enteric hollow capsule production line is wherein repeated splicing by some, realizes and automatically repeatedly dip in glue.
Along with going deep into of capsule technique research, the cyst wall that it is found that capsulae enterosolubilis has adstringency, not only be difficult to swallow, also may cause vomiting, esophagus also be had to side effect, thus, be necessary that coated one deck mouthfeel is applicable again in outer capsule layer, to esophagus close friend's adventitia, thus, enteric hollow capsule production line is proposed to requirements at the higher level.
Summary of the invention
Technical problem to be solved by this invention is for the problems referred to above, a kind of full-automatic enteric hollow capsule moulding of the formula of dipping in manufacturing line that can repeatedly automatically dip in glue is provided more, so that production has multi-level cyst wall, be applicable to the Capsules of esophagus, stomach and enteron aisle, to improve the quality of Capsules product.
For solving the problems of the technologies described above, the technical solution adopted in the present invention is the full-automatic enteric hollow capsule moulding of a kind of formula of dipping in manufacturing line more, comprises frame, main workbench, main electric cabinet, main driving, automatic machine, oiling station, dips in adhesive dispenser, capsule die, front device, conveying device, rear electric cabinet, lifting device, pusher device, drying device and the stripper apparatus of pushing away; Wherein, main workbench is arranged on frame front end, rear electric cabinet, lifting device, pusher device are arranged on frame rear end and interconnect, main electric cabinet, main driving, automatic machine, oiling station, dip in adhesive dispenser, capsule die, frontly push away device and stripper apparatus is arranged on main workbench and interconnects, conveying device is arranged in frame and with main electric cabinet and is connected with drying device; It is characterized in that outside and the bottom of dipping in adhesive dispenser also installed heater, the middle part of frame has been installed and has been dipped in again workbench and three and dip in workbench; Described dip in again electric cabinet B has been installed on workbench, drive B, automatic machine B, dip in adhesive dispenser B and before push away device B, wherein drive B with automatic machine B, dip in adhesive dispenser B and be connected, electric cabinet B with front push away device B and be connected; Described three dip in electric cabinet C has been installed on workbench, drive C, automatic machine C, heater C, dip in adhesive dispenser C and before push away device C, wherein drive C with automatic machine C, dip in adhesive dispenser C and be connected, electric cabinet C is connected with heater C, the front device C that pushes away, and heater C is arranged on outside and the bottom of dipping in adhesive dispenser C.
When production line work, start main electric cabinet, main driving, electric cabinet B, drive B, electric cabinet C, drive C and rear electric cabinet, the capsule raw material glue A that completes colloidal sol is input to and dips in adhesive dispenser, start heater simultaneously and make glue A keep temperature required, first by oiling station to capsule die oiling, then capsule die is transferred to and dips in adhesive dispenser and dip in glue, then by front pushing away device, the capsule die dipping in after glue is pushed in conveying device, in the process of carrying, carry out preliminarily dried by drying device, dip in again workbench until be delivered to, dipping in again on workbench, glue liquid B is input to and dips in adhesive dispenser B, after capsule die is transported to and dips in again on workbench, again dip in glue by dipping in adhesive dispenser B crawl capsule die, then by front pushing away device B, the capsule die dipping in again after glue liquid B is pushed in conveying device, in the process of carrying, continued to be dried by drying device, dip in workbench until be delivered to three, dip on workbench three, glue C is input to and dips in adhesive dispenser C, start heater C simultaneously and make glue C keep temperature required, capsule die be transported to three dip on workbench after, dip in for the third time glue by dipping in adhesive dispenser C crawl capsule die, then by front pushing away device C, the capsule die dipping in after glue for three times is pushed in conveying device, in the process of carrying, continued dry by drying device, until be delivered to lifting device, move to pusher device by lifting device, by pusher device, capsule die is pushed in conveying device again, carry and get back to main workbench by conveying device, in the process of carrying, continued dry by drying device, then carry out the demoulding by stripper apparatus, obtain Capsules moulded blank, capsule die after the demoulding is sent back to oiling station simultaneously, complete the enteric hollow capsule moulding manufacture of a circulation.
Further, can set up as required four and dip in workbench or the glue workbench that dips in more.
Further, capsule die is made up of base plate and large knitting needle, base plate is cuboid strip, it is cylindric that large knitting needle is, multiple large knitting needles interval is arranged on same backplate surface, described large knitting needle material adopts Special capsule mould alloy steel, and its constituent and mass percent are: C:2.30~2.45%, Cr:0.55%, Si :≤0.40%, Mn :≤0.30%, Ni :≤0.10%, Cu :≤0.10%, S :≤0.030%, P :≤0.030%, and surplus is Fe. Be conducive to like this after glue dips in glue on large knitting needle carry out the demoulding, reduce capsule ghost depression rate.
The invention has the beneficial effects as follows on original disposable basis of dipping in glue and oven dry manufacture hollow capsule production line and added heater, also add and dipped in again workbench and three and dip in workbench, can make glue keep necessary temperature and melt and dissolved degree, be convenient to glue evenly to dip in glue, can avoid capsule wall to occur even micropore situation of gage distortion, improve the colloid amount of dipping in; Can also on capsule die, divide and dip in glue three times simultaneously, provide respectively the capsule raw material containing different component or component by the solf device dipping in difference on glue workbench, so that it is corresponding suitable melt and dissolved that enteric hollow capsule product obtains at different parts such as esophagus, stomach, intestines, the digestion of suitable different parts and absorption; In addition, the large knitting needle that the material that adopts special source materials material and formula to obtain is made, can carry out the demoulding to dipping in the Capsules blank forming after glue better, reduces capsule ghost depression rate.
Brief description of the drawings
Fig. 1 is the full-automatic enteric hollow capsule moulding of the present invention's formula of dipping in manufacturing line overall structure schematic diagram more.
Fig. 2 is the structure for amplifying schematic diagram of the interior part of abcd frame in Fig. 1.
Fig. 3 is the structure for amplifying schematic diagram of the interior part of abef frame in Fig. 1.
In figure: 1. frame, 2. main workbench, 3. main electric cabinet, 4. main driving, 5. automatic machine, 6. oiling station, 7. dip in adhesive dispenser, 8. capsule die, 9. before push away device, 10. conveying device, 11. rear electric cabinets, 12. lifting devices, 13. pusher devices, 14. drying devices, 15. stripper apparatus, 16. heaters, 17. dip in workbench again, 18. 3 dip in workbench, 19. electric cabinet B, 20. drive B, 21. automatic machine B, 22. dip in adhesive dispenser B, before 23., push away device B, 24. electric cabinet C, 25. drive C, 26. automatic machine C, 27. heater C, 28. dip in adhesive dispenser C, before 29., push away device C.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described, and following examples are intended to illustrate the present invention instead of limitation of the invention further, should not limit the scope of the invention with this.
Embodiment 1.
As shown in the figure, manufacture the full-automatic enteric hollow capsule moulding of a kind of formula of dipping in manufacturing line more, comprise frame 1, main workbench 2, main electric cabinet 3, main driving 4, automatic machine 5, oiling station 6, dip in adhesive dispenser 7, capsule die 8, front device 9, conveying device 10, rear electric cabinet 11, lifting device 12, pusher device 13, drying device 14 and the stripper apparatus 15 of pushing away; Wherein, main workbench 2 is arranged on frame 1 front end, rear electric cabinet 11, lifting device 12, pusher device 13 are arranged on frame 1 rear end and interconnect, main electric cabinet 3, main driving 4, automatic machine 5, oiling station 6, dip in adhesive dispenser 7, capsule die 8, frontly push away device 9 and stripper apparatus 10 is arranged on main workbench and interconnects, conveying device 10 is arranged in frame 1 and with main electric cabinet 3 and is connected with drying device 14; Then in outside and the bottom of dipping in adhesive dispenser 7, heater 16 is also installed, is dipped in again workbench 17 and three in the installation of the middle part of frame 1 and dip in workbench 18; Described dip in again electric cabinet B19 has been installed on workbench 17, drive B20, automatic machine B21, dip in adhesive dispenser B22 and before push away device B23, wherein drive B20 with automatic machine B21, dip in adhesive dispenser B22 and be connected, electric cabinet B23 with front push away device B23 and be connected; Described three dip in electric cabinet C24 has been installed on workbench 18, drive C25, automatic machine C26, heater C27, dip in adhesive dispenser C28 and before push away device C29, wherein drive C25 with automatic machine C26, dip in adhesive dispenser C28 and be connected, electric cabinet C24 is connected with heater C27, the front device C29 that pushes away, heater C27 is arranged on outside and the bottom of dipping in adhesive dispenser C28, has so just made the full-automatic enteric hollow capsule moulding of the present invention's formula of dipping in manufacturing line more.
When production line work, start main electric cabinet 3, main driving 4, electric cabinet B19, drive B20, electric cabinet C24, drive C25 and rear electric cabinet 11, the capsule raw material glue A that completes colloidal sol is input to and dips in adhesive dispenser 7, start heater 16 simultaneously and make glue A keep temperature required, first give capsule die 8 oilings by oiling station 6, then capsule die 8 is transferred to and dips in adhesive dispenser 7 and dip in glue, then by front pushing away device 9, the capsule die 8 dipping in after glue is pushed in conveying device 10, in the process of carrying, carry out preliminarily dried by drying device 14, dip in again workbench 17 until be delivered to, dipping in again on workbench 17, glue liquid B is input to and dips in adhesive dispenser B22, after capsule die 8 is transported to and dips in again on workbench 17, again dip in glue by dipping in adhesive dispenser B22 crawl capsule die 8, then by front pushing away device B23, the capsule die 8 dipping in again after glue liquid B is pushed in conveying device 10, in the process of carrying, continued to be dried by drying device 14, dip in workbench 18 until be delivered to three, dip on workbench 18 three, glue C is input to and dips in adhesive dispenser C28, start heater C27 simultaneously and make glue C keep temperature required, capsule die 8 be transported to three dip on workbench 18 after, dip in for the third time glue by dipping in adhesive dispenser C28 crawl capsule die 8, then by front pushing away device C29, the capsule die 8 dipping in after glue for three times is pushed in conveying device 10, in the process of carrying, continued dry by drying device 14, until be delivered to lifting device 12, move to pusher device 13 by lifting device 12, by pusher device 13, capsule die 8 is pushed in conveying device 10 again, carry and get back to main workbench 2 by conveying device 10, in the process of carrying, continued dry by drying device 14, then filling 15 by the demoulding puts and carries out the demoulding, obtain Capsules moulded blank, capsule die after the demoulding 8 is sent back to oiling station 6 simultaneously, complete the enteric hollow capsule moulding manufacture of a circulation.
Embodiment 2.
The large knitting needle (control group) and the large knitting needle (experimental group) that adopts capsule die steel alloy special in the present invention to make that adopt common die material to make carry out production check experiment.
Capsule die steel alloy of the present invention, its constituent and mass percent are: C:2.30~2.45%, Cr:0.55%, Si :≤0.40%, Mn :≤0.30%, Ni :≤0.10%, Cu :≤0.10%, S :≤0.030%, P :≤0.030%, and surplus is Fe.
Control group and experimental group all adopt same releasing agent to carry out oiling, the temperature that all keeps dry is 30-35 DEG C, while keeping dipping in glue respectively, glue temperature is 35-38 DEG C (experiment one), 38-42 DEG C (experiment two), 42-45 DEG C (experiment three), through control experiment, the Capsules ghost depression rate obtaining is different greatly. The Capsules quantity contrast that its depression degree is greater than 0.5mm is listed as follows:
The finished product depression rate of the Capsules that the large knitting needle that in visible material the present invention, capsule die steel alloy is made is produced only has respectively 2.5%, 3.1%, 2.8%, and the finished product depression rate that adopts conventional capsule mould large knitting needle to produce Capsules is respectively 10.1%, 9.7%, 10.6%, production qualification rate of the present invention has obtained greatly improving.

Claims (4)

1. dip in the full-automatic enteric hollow capsule moulding of formula manufacturing line more, comprise frame (1), main workbench (2), main electric cabinet (3), main driving (4), automatic machine (5), oiling station (6), dip in adhesive dispenser (7), capsule die (8), front device (9), conveying device (10), rear electric cabinet (11), lifting device (12), pusher device (13), drying device (14) and the stripper apparatus (15) of pushing away; Wherein, main workbench (2) is arranged on frame front end (1), rear electric cabinet (11), lifting device (12), pusher device (13) are arranged on frame (1) rear end and interconnect, main electric cabinet (3), main driving (4), automatic machine (5), oiling station (6), dip in adhesive dispenser (7), capsule die (8), front device (9) and the stripper apparatus (15) of pushing away is arranged on main workbench (2) and goes up and interconnect, it is upper and be connected with main electric cabinet (3) that conveying device (10) and drying device (14) are arranged on frame (1); It is characterized in that outside and the bottom of dipping in adhesive dispenser (7) also installed heater (16), the middle part of frame (1) has been installed and has been dipped in again workbench (17) and three and dip in workbench (18); Described dipping in again on workbench (17) installed electric cabinet B(19), drive B(20), automatic machine B(21), dip in adhesive dispenser B(22) and before push away device B(23), wherein drive B(20) with automatic machine B(21), dip in adhesive dispenser B(22) be connected, electric cabinet B(19) with front push away device B(23) be connected; Described three dip on workbench (18) electric cabinet C(24 has been installed), drive C(25), automatic machine C(26), heater C(27), dip in adhesive dispenser C(28) and before push away device C(29), wherein drive C(25) with automatic machine C(26), dip in adhesive dispenser C(28) be connected, electric cabinet C(24) with heater C(27), the front device C(29 that pushes away) be connected, heater C(27) be arranged on and dip in adhesive dispenser C(28) outside and bottom.
2. according to claim 1 dip in the full-automatic enteric hollow capsule moulding of formula manufacturing line more, it is characterized in that being also provided with four dips in workbench.
3. according to claim 1 dip in the full-automatic enteric hollow capsule moulding of formula manufacturing line more, it is characterized in that being also provided with and dip in workbench more.
4. the full-automatic enteric hollow capsule moulding of the formula manufacturing line that dips according to claim 1 more, it is characterized in that described capsule die is made up of base plate and large knitting needle, base plate is cuboid strip, it is cylindric that large knitting needle is, multiple large knitting needles interval is arranged on same backplate surface, described large knitting needle material adopts Special capsule mould alloy steel, its constituent and mass percent are: C:2.30~2.45%, Cr:0.55%, Si :≤0.40%, Mn :≤0.30%, Ni :≤0.10%, Cu :≤0.10%, S :≤0.030%, P :≤0.030%, and surplus is Fe.
CN201610103513.4A 2016-02-25 2016-02-25 Multi-dipping-type full-automatic enteric hollow capsule forming manufacturing production line Pending CN105581909A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610103513.4A CN105581909A (en) 2016-02-25 2016-02-25 Multi-dipping-type full-automatic enteric hollow capsule forming manufacturing production line

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Application Number Priority Date Filing Date Title
CN201610103513.4A CN105581909A (en) 2016-02-25 2016-02-25 Multi-dipping-type full-automatic enteric hollow capsule forming manufacturing production line

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965089A (en) * 1989-04-10 1990-10-23 Sauter Manufacturing Corp. Method and apparatus for the gelatin coating of caplets
CN2079966U (en) * 1990-12-12 1991-07-03 浙江省新昌县药用设备厂 Automatic temp.-controllable glue dipping machine
EP0448231A1 (en) * 1990-02-22 1991-09-25 McNEIL-PPC, INC. Improved coated medicaments and apparatus and methods for making same
CN102363341A (en) * 2011-11-01 2012-02-29 黄光洁 Medicinal capsule mold and making technology thereof
CN204178253U (en) * 2014-09-10 2015-02-25 浙江绿健胶囊有限公司 A kind of automatic capsule production line control system
CN104546487A (en) * 2014-12-05 2015-04-29 丹东金丸集团有限公司 Fully-automatic enteric capsule production line
CN204585667U (en) * 2015-04-29 2015-08-26 青岛微恒工程有限公司 A kind of servo dips in adhesive dispenser

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965089A (en) * 1989-04-10 1990-10-23 Sauter Manufacturing Corp. Method and apparatus for the gelatin coating of caplets
EP0448231A1 (en) * 1990-02-22 1991-09-25 McNEIL-PPC, INC. Improved coated medicaments and apparatus and methods for making same
CN2079966U (en) * 1990-12-12 1991-07-03 浙江省新昌县药用设备厂 Automatic temp.-controllable glue dipping machine
CN102363341A (en) * 2011-11-01 2012-02-29 黄光洁 Medicinal capsule mold and making technology thereof
CN204178253U (en) * 2014-09-10 2015-02-25 浙江绿健胶囊有限公司 A kind of automatic capsule production line control system
CN104546487A (en) * 2014-12-05 2015-04-29 丹东金丸集团有限公司 Fully-automatic enteric capsule production line
CN204585667U (en) * 2015-04-29 2015-08-26 青岛微恒工程有限公司 A kind of servo dips in adhesive dispenser

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Application publication date: 20160518