CN105581819A - Patent ductus arteriosus closure device - Google Patents

Patent ductus arteriosus closure device Download PDF

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Publication number
CN105581819A
CN105581819A CN201610065190.4A CN201610065190A CN105581819A CN 105581819 A CN105581819 A CN 105581819A CN 201610065190 A CN201610065190 A CN 201610065190A CN 105581819 A CN105581819 A CN 105581819A
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Prior art keywords
disk
packing
ductus arteriosus
outer diameter
cylindrical packing
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CN201610065190.4A
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Chinese (zh)
Inventor
吕海涛
钱为国
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Affiliated Childrens Hospital of Soochow University
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Affiliated Childrens Hospital of Soochow University
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Priority to CN201610065190.4A priority Critical patent/CN105581819A/en
Publication of CN105581819A publication Critical patent/CN105581819A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12027Type of occlusion
    • A61B17/12031Type of occlusion complete occlusion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12122Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder within the heart
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214Coils or wires
    • A61B17/12145Coils or wires having a pre-set deployed three-dimensional shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214Coils or wires
    • A61B17/1215Coils or wires comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12159Solid plugs; being solid before insertion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831Material properties

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Surgical Instruments (AREA)
  • Prostheses (AREA)

Abstract

The invention belongs to the field of medical devices, and particularly relates to a closure device suitable for an interventional closure operation of a patent ductus arteriosus patient. The patent ductus arteriosus closure device comprises a first disc and a cylindrical filling body, the first disc and the cylindrical filling body are formed by weaving alloy metal wires, and a connecting part capable of being bent and sized for supporting is arranged between the first disc and the cylindrical filling body. The first disc/second disc of the closure device is connected with the cylindrical filling body through the connecting part, the connecting part has certain activity, an angle can be formed, the connecting part can be attached to the blood vessel wall better, and therefore the risks of aorta deformation and lumen stenosis are reduced.

Description

A kind of patend ductus arteriosus occluder
Technical field
The invention belongs to field of medical devices, the plugging device that is particularly applicable to patent ductus arteriosus patient and carries out transcatheter operation.
Background technology
Patent ductus arteriosus is one of modal congenital heart disease, accounts for congenital heart disease 10%, is the patent pipeline of descending aorta between hypomere and the left pulmonary artery of subclavian artery, and size and geometric differs, and is mainly divided into according to form:
1. funnel type: sustainer end is thicker, pulmonary artery end is narrower, is funnel-form, and this kind of is clinical common;
2. cast: it is consistent with Pulmonic two ends diameter that conduit connects sustainer;
3. window type: conduit is very short but diameter is very large, is window spline structure;
4. bell type: conduit two ends are thick and middle thin;
5. knurl type: conduit two ends are thin but centre is Ectasia.
Transcatheter is the first-selected methods for the treatment of of patent ductus arteriosus at present, clinical normal selection turn (Coil), PDA plugging device (Amplatzerductoccluder), ADO-II, chamber lack the plugging devices such as plugging device (VSDoccluder) at present, respectively there are pluses and minuses, its clinical FAQs:
1.PDA plugging device: have ADO-I, domestic similar plugging device, for mushroom umbrella, the medium-and-large-sized PDA that is greater than 2mm for diameter has good plugging effect, but for the little PDA that forward method is difficult to pass through through pulmonary artery seal wire, shutoff is more difficult, and can not angulation due to left side card at young infant, easily cause that sustainer distortion and official jargon are narrow. There is stainless steel riveting plugging device both sides, protrude surface, are unfavorable for the epithelialization on plugging device surface, affect the integrality of endothelium, have thrombosed Potential feasibility, and tenor is higher, built-in polyester fiber choked flow film non-degradable, has potential bio-toxicity;
2. turn: Cook company of the conventional U.S. produces at present controllable spring embolus and German pfm spring embolus, turn can only be used for the arterial duct that diameter is less, sometimes need to insert multiple turns for the larger arterial duct of diameter, send with release tech requirement higher, operate more difficultly, and residual shunt rate is higher;
3.ADO-II is double disk structure, be applicable to the shutoff treatment of small-sized non-window type PDA, its advantage is that tenor is few, easy to operate, can send from femoral artery and femoral vein approach, delivery sheath pipe is little, be convenient to send, but shortcoming is it, fixing card is large, and waist is long, less for PDA ampulla, the shorter infant of length can cause left pulmonary artery or aortostenosis;
4. chamber lacks plugging umbrella: can lack plugging umbrella in the chamber of selecting for thick PDA, membranous part VSD plugging device is used for the PDA that length is less than 4mm, as be greater than 4mm, can make left and right dish cannot open in PDA, cause arteriarctia or postoperative coming off, now can select pars muscularis VSD plugging device, the general hospital of pars muscularis VSD plugging device is not standing, has limited application.
5. angulation arterial duct plugging device: complicated operation, misoperation, can cause that plugging device comes off.
Summary of the invention
The object of the present invention is to provide a kind of patend ductus arteriosus occluder.
When current clinical PDA transcatheter operation, need the plugging device of dissimilar, different model for subsequent use, increased the selection difficulty of surgery cost and plugging device, therefore, another object of the present invention is to simplify the type of patend ductus arteriosus occluder.
Another object of the present invention is to reduce conventional patend ductus arteriosus occluder at present to cause sustainer, the iatrogenic narrow risk of pulmonary artery.
Another object of the present invention is the metal material content (adopting part absorbable material) reducing in plugging device.
Another object of the present invention is to use more vaginula pipe, more easily sends and discharges plugging device.
In order to realize foregoing invention object, technical scheme provided by the invention is: a kind of patend ductus arteriosus occluder, comprise one first disk, a cylindrical packing, described the first disk and cylindrical packing are formed by the braiding of alloying metal silk, are provided with the connecting portion that a bent sizing is supported between described the first disk and cylindrical packing.
In technique scheme, described patend ductus arteriosus occluder is along axis direction, from pulmonary artery side direction sustainer side, be provided with successively one first disk, a junction, a packing, not only bent while of described connecting portion but also can provide sizing to support, make to be between the first disk and packing the angle of any needs.
In technique scheme, the external diameter of described the first disk is less than described cylindrical packing external diameter; Described the first disk is positioned at the nearly pulmonary artery side of described cylindrical packing; The end face central authorities of the nearly sustainer side of described cylindrical packing are provided with a knitted body and close up, and fix a stainless steel threaded post in closing in place, and when use, plugging device discharges from sustainer side. Described packing outer diameter is 4mm~8mm, and the length of packing is 5mm or 6mm, and the outer diameter of described the first disk is than the little 2mm~4mm of packing outer diameter. Be suitable for the patent ductus arteriosus patient of the elongated cast of interior diameter 2~3mm. The plugging device of this size range does not adopt choked flow film, more easily moulding, can adopt more vaginula pipe to carry, thereby reduce the damage to blood vessel.
In another kind of technical scheme, the external diameter of described the first disk is greater than described cylindrical packing external diameter; Described the first disk is positioned at the nearly sustainer side of described cylindrical packing, and described patend ductus arteriosus occluder, along axis direction, from pulmonary artery side direction sustainer side, is provided with a cylindrical packing, a junction, one first disk successively; The end face central authorities of the nearly pulmonary artery side of described cylindrical packing are provided with a knitted body and close up, and fix a stainless steel threaded post in closing in place, and when use, plugging device discharges from pulmonary artery side. Described packing outer diameter is 4mm~12mm, and the length of packing is 5mm or 6mm, and the nearly sustainer side in described cylindrical packing is provided with a choked flow film; The outer diameter of described the first disk is than the large 2mm~4mm of packing outer diameter. Be suitable for the patent ductus arteriosus patient of interior diameter 2~6mm funnel type.
In another kind of technical scheme, patend ductus arteriosus occluder, comprises one first disk, a cylindrical packing, one second disk; And along axis direction, from pulmonary artery side direction sustainer side, described plugging device is provided with one first disk, a cylindrical packing, one second disk successively; Between described cylindrical packing and the first disk, the second disk, be respectively equipped with the connecting portion that a bent sizing is supported; And the external diameter of described cylindrical packing is greater than the external diameter of the first disk, meanwhile, the external diameter of described cylindrical packing is less than the external diameter of the second disk; The end face central authorities of the nearly pulmonary artery side of described the first disk are provided with a knitted body and close up, and fix a stainless steel threaded post in closing in place, and when use, plugging device discharges from pulmonary artery side. Described packing outer diameter is 12mm~24mm, and the length of packing is 5mm or 6mm, and nearly sustainer side in described cylindrical packing and nearly pulmonary artery side are provided with a choked flow film separately; The outer diameter of described the first disk is than the little 2mm~4mm of packing outer diameter; The outer diameter of described the second disk is than the large 2mm~4mm of packing outer diameter. Be suitable for the patent ductus arteriosus patient of interior diameter 5~15mm funnel type.
In technique scheme, described connecting portion is compiled braiding by a branch of alloying metal silk or at least one laminated golden wire netting and is formed. Described connecting portion is both bent or/and rotation can provide certain support strength simultaneously, make doctor in the time using this patend ductus arteriosus occluder, can be according to true form and the position of patient's patent pipeline, by described the first disk or/and the second disk and pulmonary artery/aortic blood tube wall fit better, thereby better plugging device is fixed in the pipeline of patent, prevent from when plugging device from discharging dropping to sustainer from pulmonary artery, or drop to pulmonary artery from sustainer. In preferred technical scheme, the outer diameter of described connecting portion is less than 1mm, and length is less than 1mm.
In technique scheme, described choked flow film is selected from choked flow film of the prior art or the absorbable fibroin protein film of part.
In actual use procedure, with reference to descending aorta radiography result, Cardiac ultrasound, pulmonary artery pressure selects suitable plugging device to carry out shutoff, the general plugging device column type packing diameter of selecting is compared with the large 4-6mm of stenosis of arterial duct, length is selected according to measurement result, adopt respectively forward method or inverse method release according to PDA size and type, when stenosis diameter as in PDA is less than 2-4mm, the small-sized plugging device of general selection, employing inverse method discharges, it is femoral artery-descending aorta-PDA-pulmonary artery that inverse method discharges, first discharge right side card, then discharge column type packing. in the time selecting large-scale plugging device, generally adopt forward method to discharge, forward method release is inferior caval vein-right room-right ventricle-pulmonary artery-PDA-descending aorta, first discharge descending aorta end plate face, then pull back, make left card embed PDA ampulla, then discharge bluff body and right side card.
Due to the application of technique scheme, compared to the prior art, the present invention has the following advantages:
(1) plugging device of the present invention is rational in infrastructure, possesses Multiple Type, can meet the shutoff of the PDA of different shape and length, column type packing is by strutting patent ductus arteriosus section, and the blessing power of utilizing arterial duct realizes fixingly, what make that plugging device can be firm is fixed in arterial duct, the elongation that column type packing can be suitable in length, there is the wider scope of application, can solve in operation due to the poor problem of the improper plugging effect bringing of plugging device length;
(2) the first disk/the second disk of plugging device described in the present invention is connected with column type packing by connecting portion, described connecting portion has certain activity, can angulation, the vascular wall of can fitting better, thus lower the risk of sustainer distortion and luminal stenosis;
(3) plugging device described in the present invention is formed by Nitinol braiding, only fix one piece of stainless steel threaded post living closing in place, reduced metal consumption, use part absorbable fibroin protein film, be more conducive to endothelialization, reduced the risk of thrombus and potential bio-toxicity.
Brief description of the drawings
Fig. 1 is the schematic diagram of the patend ductus arteriosus occluder of embodiment mono-and embodiment bis-;
Fig. 2 is the schematic diagram of the patend ductus arteriosus occluder of embodiment tri-to embodiment five;
Fig. 3 is the schematic diagram of the inner choked flow film of patend ductus arteriosus occluder of embodiment tri-to embodiment five;
Fig. 4 is the schematic diagram of the patend ductus arteriosus occluder of embodiment six to embodiment eight;
Fig. 5 is the schematic diagram of the inner choked flow film of patend ductus arteriosus occluder of embodiment six to embodiment eight;
Wherein, 1 is the first disk, and 2 is connecting portion, and 3 is cylindrical packing, and 4 is threaded post, and 5 is choked flow film, and 6 is the second disk.
Detailed description of the invention
Below in conjunction with embodiment and accompanying drawing, the invention will be further described.
Embodiment mono-:
As shown in Figure 1, a kind of patend ductus arteriosus occluder, comprise one first disk 1, a cylindrical packing 3, described the first disk 1 and cylindrical packing 3 are formed by the braiding of alloying metal silk, are provided with the connecting portion 2 that a bent sizing is supported between described the first disk 1 and cylindrical packing 3.
Be that described patend ductus arteriosus occluder is along axis direction, from pulmonary artery side direction sustainer side, be provided with successively one first disk 1, a junction 2, a packing 3, the not only bent while of described connecting portion but can provide sizing support, make to be between the first disk and packing the angle of any needs, make better laminating pulmonary artery of the first disk 1, reduced traditional PD A plugging device and inserted the upper limb of rear disk and charge in aorta lumen and the sustainer that aortal tractive is caused distortion.
Described the first disk 1 is positioned at the nearly pulmonary artery side of described cylindrical packing 3; The end face central authorities of the nearly sustainer side of described cylindrical packing 3 are provided with a knitted body and close up, and fix a stainless steel threaded post 4 in closing in place, and when use, plugging device discharges from sustainer side. Described packing outer diameter is 6mm, and the length of packing is 5mm, and the outer diameter of described the first disk is 4mm. Be suitable for the patent ductus arteriosus patient of the elongated cast of interior diameter 2~3mm. The plugging device of this size range does not adopt choked flow film, more easily moulding, can adopt more vaginula pipe to carry, thereby reduce the damage to blood vessel.
Embodiment bis-:
A kind of patend ductus arteriosus occluder, structure is similar to patend ductus arteriosus occluder described in embodiment mono-, and difference is, and described column type packing outer diameter is 4mm, and length is 5mm, the outer diameter of described the first disk is 2mm.
Embodiment tri-:
As shown in Figure 2,3, a kind of patend ductus arteriosus occluder, along axis direction, from pulmonary artery side direction sustainer side, is provided with a cylindrical packing 3, a junction 2, one first disk 1 successively; The end face central authorities of the nearly pulmonary artery side of described cylindrical packing 3 are provided with a knitted body and close up, and fix a stainless steel threaded post 4 in closing in place, and when use, plugging device discharges from pulmonary artery side. Described packing 3 outer diameters are 8mm, and the length of packing 3 is 6mm, and the nearly sustainer side in described cylindrical packing 3 is provided with a choked flow film 5; The outer diameter 10mm of described the first disk 1. Be suitable for the patent ductus arteriosus patient of interior diameter 2~6mm funnel type.
Embodiment tetra-:
A kind of patend ductus arteriosus occluder, structure is similar to patend ductus arteriosus occluder described in embodiment bis-, and difference is, and described column type packing outer diameter is 12mm, and length is 6mm, the outer diameter of described the first disk is 14mm.
Embodiment five:
A kind of patend ductus arteriosus occluder, structure is similar to patend ductus arteriosus occluder described in embodiment bis-, and difference is, and described column type packing outer diameter is 4mm, and length is 5mm, the outer diameter of described the first disk is 6mm.
Embodiment six:
As shown in Figure 4,5, a kind of patend ductus arteriosus occluder, comprises one first disk 1, a cylindrical packing 3, one second disk 6; And along axis direction, from pulmonary artery side direction sustainer side, described plugging device is provided with one first disk 1, a cylindrical packing 3, one second disk 6 successively; Between described cylindrical packing 3 and the first disk 1, the second disk 6, be respectively equipped with the connecting portion 2 that a bent sizing is supported; And the external diameter of described cylindrical packing 3 is greater than the external diameter of the first disk 1, meanwhile, the external diameter of described cylindrical packing 3 is less than the external diameter of the second disk 6; The end face central authorities of the nearly pulmonary artery side of described the first disk 1 are provided with a knitted body and close up, and fix a stainless steel threaded post 4 in closing in place, and when use, plugging device discharges from pulmonary artery side.
Described packing 3 outer diameters are 14mm, and the length of packing 3 is 6mm, and nearly sustainer side in described cylindrical packing and nearly pulmonary artery side are provided with a choked flow film 5 separately; The outer diameter of described the first disk 1 is 12mm; The outer diameter of described the second disk 6 is 16mm. Be suitable for the patent ductus arteriosus patient of interior diameter 5~15mm funnel type.
Embodiment seven:
A kind of patend ductus arteriosus occluder, structure is identical with plugging device described in embodiment six, and difference is: packing outer diameter is 12mm, and the length of bluff body is 5mm. The outer diameter of described the first disk is 10mm, and the outer diameter of described the second disk is 14mm.
Embodiment eight:
A kind of patend ductus arteriosus occluder, structure is identical with plugging device described in embodiment six, and difference is: packing outer diameter is 22mm, and the length of bluff body is 5mm. The outer diameter of described the first disk is 18mm, and the outer diameter of described the second disk is 26mm.

Claims (10)

1. a patend ductus arteriosus occluder, comprise one first disk, a cylindrical packing, described the first disk and cylindrical packing are formed by the braiding of alloying metal silk, it is characterized in that, are provided with the connecting portion that a bent sizing is supported between described the first disk and cylindrical packing.
2. patend ductus arteriosus occluder according to claim 1, is characterized in that: the external diameter of described the first disk is less than described cylindrical packing external diameter; Described the first disk is positioned at the nearly pulmonary artery side of described cylindrical packing; The end face central authorities of the nearly sustainer side of described cylindrical packing are provided with a knitted body and close up, and fix a stainless steel threaded post in closing in place, and when use, plugging device discharges from sustainer side.
3. patend ductus arteriosus occluder according to claim 1, is characterized in that: the external diameter of described the first disk is greater than described cylindrical packing external diameter; Described the first disk is positioned at the nearly sustainer side of described cylindrical packing; The end face central authorities of the nearly pulmonary artery side of described cylindrical packing are provided with a knitted body and close up, and fix a stainless steel threaded post in closing in place, and when use, plugging device discharges from pulmonary artery side.
4. patend ductus arteriosus occluder according to claim 3, is characterized in that: the nearly sustainer side in described cylindrical packing is provided with a choked flow film.
5. patend ductus arteriosus occluder according to claim 1, it is characterized in that: described plugging device also comprises one second disk, and along axis direction, from pulmonary artery side direction sustainer side, described plugging device is provided with one first disk, a cylindrical packing, one second disk successively; Between described cylindrical packing and the first disk, the second disk, be respectively equipped with the connecting portion that a bent sizing is supported; And the external diameter of described cylindrical packing is greater than the external diameter of the first disk, meanwhile, the external diameter of described cylindrical packing is less than the external diameter of the second disk; The end face central authorities of the nearly pulmonary artery side of described the first disk are provided with a knitted body and close up, and fix a stainless steel threaded post in closing in place, and when use, plugging device discharges from pulmonary artery side.
6. patend ductus arteriosus occluder according to claim 5, is characterized in that: the nearly sustainer side in described cylindrical packing and nearly pulmonary artery side are provided with a choked flow film separately.
7. patend ductus arteriosus occluder according to claim 2, is characterized in that: described packing outer diameter is 4mm~8mm, and the length of packing is 5mm or 6mm, the outer diameter of described the first disk is than the little 2mm~4mm of packing outer diameter; Be suitable for the elongated cast of interior diameter 2~3mm.
8. patend ductus arteriosus occluder according to claim 3, is characterized in that: described packing outer diameter is 4mm~12mm, and the length of packing is 5mm or 6mm, the outer diameter of described the first disk is than the large 2mm~4mm of packing outer diameter; Be suitable for interior diameter 2~6mm funnel type.
9. patend ductus arteriosus occluder according to claim 5, is characterized in that: described packing outer diameter is 12mm~24mm, and the length of packing is 5mm or 6mm, the outer diameter of described the first disk is than the little 2mm~4mm of packing outer diameter; The outer diameter of described the second disk is than the large 2mm~4mm of packing outer diameter; Be suitable for interior diameter 5~15mm funnel type.
10. according to patend ductus arteriosus occluder described in claim 1 to 9, it is characterized in that: the connecting portion that described bent sizing is supported is a branch of wire, and described patend ductus arteriosus occluder is one-body molded by the braiding of alloying metal silk.
CN201610065190.4A 2015-09-15 2016-01-29 Patent ductus arteriosus closure device Pending CN105581819A (en)

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CN201510582773X 2015-09-15
CN201610065190.4A CN105581819A (en) 2015-09-15 2016-01-29 Patent ductus arteriosus closure device

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