CN105561214A - 一种治疗冠心病的中药组合物 - Google Patents

一种治疗冠心病的中药组合物 Download PDF

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CN105561214A
CN105561214A CN201610112065.4A CN201610112065A CN105561214A CN 105561214 A CN105561214 A CN 105561214A CN 201610112065 A CN201610112065 A CN 201610112065A CN 105561214 A CN105561214 A CN 105561214A
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heart disease
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杨传胜
杨艳艳
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Abstract

本发明涉及一种治疗冠心病的中药组合物,由以下原料中药组成,当归15克、玄参12克、丹参15克、茯苓10克、石菖蒲12克、远志12克、郁金10克、炙甘草5克、麦门冬12克、川芎10克、红花12克、三七15克、水蛭8克、鸡血藤12克。其中,胸闷憋气者加瓜蒌15克、薤白12克;血压高者加决明子12克、钩藤12克;植物神经功能紊乱,心率不齐者加百合10克、知母12克、石膏12克。水煎服,每日一剂,10天一个疗程。本发明诸药配伍,能活血祛瘀;行气开郁;通经活络;益气安神;补益气血,治疗冠心病标本兼治,药效直接。本发明中药制剂使用方便,价值低廉。

Description

一种治疗冠心病的中药组合物
技术领域
本发明涉及中药技术领域,具体是一种治疗冠心病的中药组合物。
背景技术
冠心病是冠状动脉血管发生动脉粥样硬化病变而引起血管腔狭窄或阻塞,造成心肌缺血、缺氧或坏死而导致的心脏病,冠心病的发作常常与季节变化、情绪激动、体力活动增加、饱食、大量吸烟和饮酒等有关。冠心病在许多发达国家排在死亡原因的第一位。冠心病的治疗包括:①生活习惯改变:戒烟限酒,低脂低盐饮食,适当体育锻炼,控制体重等;②药物治疗:抗血栓(抗血小板、抗凝),减轻心肌氧耗(β受体阻滞剂),缓解心绞痛(硝酸酯类),调脂稳定斑块(他汀类调脂药);③血运重建治疗:包括介入治疗(血管内球囊扩张成形术和支架植入术)和外科冠状动脉旁路移植术。药物治疗是所有治疗的基础。介入和外科手术治疗后也要坚持长期的标准药物治疗。对同一病人来说,处于疾病的某一个阶段时可用药物理想地控制,而在另一阶段时单用药物治疗效果往往不佳,需要将药物与介入治疗或外科手术合用。血运重建治疗主要是介入手术治疗,对病人创伤大、费用高、恢复慢,多数病人特别是老年病人难以接受。药物治疗中的中药治疗通过中药调节,补益气血,活血化瘀,改善心血管的循环,治疗冠心病及心血管病症具有标本兼治的效果,越来越受到广大患者的认同。
发明内容
本发明的目的在于提供一种治疗冠心病的中药组合物。
本发明的目是通过以下技术方案实现的:一种治疗冠心病的中药组合物,由以下原料中药组成,当归15克、玄参12克、丹参15克、茯苓10克、石菖蒲12克、远志12克、郁金10克、炙甘草5克、麦门冬12克、川芎10克、红花12克、三七15克、水蛭8克、鸡血藤12克。其中,胸闷憋气者加瓜蒌15克、薤白12克;血压高者加决明子12克、钩藤12克;植物神经功能紊乱,心率不齐者加百合10克、知母12克、石膏12克。水煎服,每日一剂,10天一个疗程。
本发明配方中各原料药的药理药效为:
当归:补血;活血;调经止痛。②《别录》:"温中止痛,除客血内塞,中风痉、汗不出,湿痹,中恶客气、虚冷,补五藏,生肌肉。
玄参:清热凉血;滋阴降火;解毒散结。《本草正义》:玄参,禀至阴之性,专主热病,味苦则泄降下行,故能治脏腑热结等证。味又辛而微咸,故直走血分而通血瘀。亦能外行于经隧,而消散热结之痈肿。
丹参:活血祛瘀,通经止痛,清心除烦,凉血消痈。《本草纲目》:活血,通心包络,治疝痛。
茯苓:利水渗湿,健脾,宁心。《本草正》:能利窍去湿,利窍则开心益智,导浊生津;去湿则逐水燥脾,补中健胃。
石菖蒲:开窍,豁痰,理气,活血,散风,去湿。《纲目》:石菖蒲气温,心气不足者用之,虚则补其母也。肝苦急,以辛补之是矣。
远志:宁心安神;祛痰开窍;解毒消肿。《本草再新》:行气散郁,并善豁痰。
郁金:行气解郁,凉血破瘀。《本草汇言》:"郁金,清气化痰,散瘀血之药也。其性轻扬,能散郁滞,顺逆气,上达高巅,善行下焦,心肺肝胃气血火痰郁遏不行者最验,故治胸胃膈痛,两胁胀满,肚腹攻疼,饮食不思等证。又治经脉逆行,吐血衄血,唾血血腥。
炙甘草:炙甘草汤具有益气滋阴,通阳复脉治疗功效。气血双补的功效和作用,以《注解伤寒论》为代表,认为炙甘草汤的功效当为气血双补,“益虚补血气而复脉”。
麦门冬:滋阴润肺;益胃生津;清心除烦。滋阴润肺;益胃生津;清心除烦。《用药心法》:补心气不足及治血妄行。《用药心法》:补心气不足及治血妄行。
川芎:活血祛瘀;行气开郁;祛风止痛。《本草正》:川芎,其性善散,又走肝经,气中之血药也。反藜芦,畏硝石、滑石、黄连者,以其沉寒而制其升散之性也。芍归俱属血药,而芎之散动尤甚于归,故能散风寒,治头痛,破瘀蓄,通血脉,解结气,逐疼痛,排脓消肿,逐血通经。
红花:活血能经;祛瘀止痛。《药品化义》:红花,善通利经脉,为血中气药,能泻而又能补,各有妙义。《药品化义》:红花,善通利经脉,为血中气药,能泻而又能补,各有妙义。
三七:散瘀止血,消肿定痛。散瘀止血,消肿定痛。
水蛭:破血逐瘀;通经消症。《本经》:主逐恶血、瘀血、月闭,破血瘕积聚,无子利水道。
鸡血藤:补血行血,通经活络。
瓜蒌:清热涤痰,宽胸散结,润肠。
薤白:通阳散结,行气导滞。用于胸痹心痛,脘腹痞满胀痛,泻痢后重。
决明子:清肝明目,利水通便,有缓泻作用,降血压降血脂。
钩藤:钩藤以带钩的茎枝入药,它具有清热平肝,息风定惊功效,现代药理实验还证明钩藤有降压作用,因此具有很高的药用价值。
百合:养阴润肺;清心安神。《日华子本草》:安心,定胆,益志,养五脏。
知母:有清热泻火除烦的作用。与石膏配伍有协同之效。
石膏:生用解肌清热,除烦止渴。
本发明诸药配伍,能活血祛瘀;行气开郁;通经活络;益气安神;补益气血,治疗冠心病标本兼治,药效直接。本中药制剂使用方便,价值低廉。
具体实施方式
下面结合实施例对本发明作进一步说明。
实施例1:一种治疗冠心病的中药组合物,由以下原料中药组成,当归15克、玄参12克、丹参15克、茯苓10克、石菖蒲12克、远志12克、郁金10克、炙甘草5克、麦门冬12克、川芎10克、红花12克、三七15克、水蛭8克、鸡血藤12克。水煎服,每日一剂,10天一个疗程。
实施例2:一种治疗冠心病的中药组合物,由以下原料中药组成,当归15克、玄参12克、丹参15克、茯苓10克、石菖蒲12克、远志12克、郁金10克、炙甘草5克、麦门冬12克、川芎10克、红花12克、三七15克、水蛭8克、鸡血藤12克、瓜蒌15克、薤白12克。水煎服,每日一剂,10天一个疗程。
实施例3:一种治疗冠心病的中药组合物,由以下原料中药组成,当归15克、玄参12克、丹参15克、茯苓10克、石菖蒲12克、远志12克、郁金10克、炙甘草5克、麦门冬12克、川芎10克、红花12克、三七15克、水蛭8克、鸡血藤12克、决明子12克、钩藤12克。水煎服,每日一剂,10天一个疗程。
实施例4:一种治疗冠心病的中药组合物,由以下原料中药组成,当归15克、玄参12克、丹参15克、茯苓10克、石菖蒲12克、远志12克、郁金10克、炙甘草5克、麦门冬12克、川芎10克、红花12克、三七15克、水蛭8克、鸡血藤12克、百合10克、知母12克、石膏12克。水煎服,每日一剂,10天一个疗程。
临床资料
病例1:黄某某,女,52岁。经常性突发左侧胸前区疼痛,持续约几分钟后自然缓解。常因劳累或情绪波动而诱发。2015年5月发作频繁,呈加剧之势,伴胸闷心悸、短气乏力。于2015年5月12日来院治疗,查体:血压180/120,HR66次/分,心律齐,未闻及明显杂音。肺呼吸音清晰。心电图:V1~V3导联的ST段水平型压低>O.1mV,T波倒置。提示心肌供血不足,诊断为冠心病心绞痛。给予本发明实施例4方剂治疗,每日1剂,水煎服。10日复诊:自诉胸前区疼痛消失,但有时胸闷气短,调方,给实施例2方继服10剂巩固疗效,康复。
病例2:李某某,男,71岁。有患冠心病史5年,2015年6月中旬病情加重,感觉间歇性胸前区疼痛并伴有胸闷,气短、心悸,脉结代,口腔溃疡。给予本发明实施例2方剂治疗,每日1剂,水煎服。10日复诊:自诉胸前区疼痛消失,继服10剂。三诊脉已不结代,心律基本正常,观察一年半,病情无反复。
病例3:王某,男,53岁,干部。2015年1月26日,因心前区疼痛伴呼吸困难入院。近2年时感心前区疼痛,痛系膨胀性或压迫感,每次持续3~5分钟,一天数次,无其它症状,休息后减轻。入院前痛渐频繁,且休息时也发作,心前区剧痛,并向左肩部、臂部放射,且伴大汗、呼吸困难。体查:体温37.8℃,心率88次/min,血压140/80mmHg。呼吸急促,口唇及指甲发绀,颈静脉稍充盈,双肺底部可闻有湿鸣,心界向左扩大,心音弱。诊断为冠心病,给予本发明实施例2方剂治疗,每日1剂,水煎服。10日复诊:自诉胸前区疼痛消失,继服10剂。症状消失,心律基本正常,观察一年半,病情无反复。
病例4:张某某,男,60岁,退休干部。2015年1月6日,突发神志不清2小时,急诊住院。病史:患者患冠心病2年,反复出现前胸部剧烈疼痛,伴胸部紧迫感,发作时伴出汗、心跳,含服酸甘油后缓解,在工作紧张或疲劳时发作频繁。入院当日下午患者略感头晕不适,突然出现心前区剧烈闷痛,继之出现神志不清。既往史:有高血压病史十余年,血压波动在21.3/13.3~22.6/14.7kPa(160/100—200/110mmHg)之间,伴头晕头疼。常服用“降压片”。诊断为冠心病发作,给予本发明实施例3方剂治疗,每日1剂,水煎服。10日复诊:自诉胸前区疼痛消失,但有时胸闷气短,调方,给实施例2方继服10剂巩固疗效,康复出院。
  本方剂观察治疗2015年来院治疗冠心病患者34例,治愈14例,显效14例,有效5例,无效1例,总有效率为97.1%。

Claims (4)

1.一种治疗冠心病的中药组合物,其特征在于,由以下原料中药组成,当归15克、玄参12克、丹参15克、茯苓10克、石菖蒲12克、远志12克、郁金10克、炙甘草5克、麦门冬12克、川芎10克、红花12克、三七15克、水蛭8克、鸡血藤12克。
2.一种治疗冠心病的中药组合物,其特征在于,由以下原料中药组成,当归15克、玄参12克、丹参15克、茯苓10克、石菖蒲12克、远志12克、郁金10克、炙甘草5克、麦门冬12克、川芎10克、红花12克、三七15克、水蛭8克、鸡血藤12克、瓜蒌15克、薤白12克。
3.一种治疗冠心病的中药组合物,其特征在于,由以下原料中药组成,当归15克、玄参12克、丹参15克、茯苓10克、石菖蒲12克、远志12克、郁金10克、炙甘草5克、麦门冬12克、川芎10克、红花12克、三七15克、水蛭8克、鸡血藤12克、决明子12克、钩藤12克。
4.一种治疗冠心病的中药组合物,其特征在于,由以下原料中药组成,当归15克、玄参12克、丹参15克、茯苓10克、石菖蒲12克、远志12克、郁金10克、炙甘草5克、麦门冬12克、川芎10克、红花12克、三七15克、水蛭8克、鸡血藤12克、百合10克、知母12克、石膏12克。
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CN105878775A (zh) * 2016-05-23 2016-08-24 陈莉莉 一种治疗心血管疾病的药物
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CN106511751A (zh) * 2017-01-03 2017-03-22 张先军 一种治疗胸痹心痛的中药组合物
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