CN105547799A - Device for rapidly freezing and thawing samples - Google Patents
Device for rapidly freezing and thawing samples Download PDFInfo
- Publication number
- CN105547799A CN105547799A CN201610055531.XA CN201610055531A CN105547799A CN 105547799 A CN105547799 A CN 105547799A CN 201610055531 A CN201610055531 A CN 201610055531A CN 105547799 A CN105547799 A CN 105547799A
- Authority
- CN
- China
- Prior art keywords
- freeze
- drying
- freezing
- plate
- drying plate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/42—Low-temperature sample treatment, e.g. cryofixation
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Drying Of Solid Materials (AREA)
Abstract
The invention discloses a freezing and drying device for rapidly freezing and thawing samples. The freezing and drying device comprises a freezing and drying frame and freezing and drying plates. Each freezing and drying plate is a single-layer thin plate and provided with holes which are used for bearing eccentric tubes containing testing samples. The freezing and drying frame is formed by connecting and assembling fixed supports, baffles, insertion grooves and front fixing rods, wherein the fixed supports are parallel to one another and perpendicular to the bottom face, the baffles are welded to the equal-height positions of all the fixed supports, the insertion grooves are welded to the adjacent lower sides of the baffles and used for inserting the sample-carrying freezing and drying plates in the freezing and drying frame, and the freezing and drying plates are fixed to the middle of the freezing and drying frame through the front fixing rods. By means of the freezing and drying device, the overall freezing and unfreezing are achieved, a large batch of samples can be repeatedly frozen and thawed, the samples can be conveniently and integrally frozen and thawed, loss of samples is reduced, the labor consumption for repeated sampling and sample arranging is lowered, and efficiency and accuracy are improved.
Description
Technical field
The invention belongs to test specimen freeze thawing equipment technical field, be specifically related to a kind of device for fast freeze-thaw sample.
Background technology
In biologic test, in order to cell lysis, promote the release of some factor or the release etc. of virus, often need fast freeze-thaw sample.
At present, the way realizing fast freeze-thaw conventional to sample is frozen-thawed.But owing to there is no supporting facilities and equipment in practical operation, first the centrifuge tube of dress sample is poured in cloth bag often, then put into liquid nitrogen snap frozen; Subsequently sample is taken out, again sequence order again after waiting sample to melt, put back in freeze-drying box, so that follow-up test operation.This process expends time in very much, and when sample size is large, needs several personnel to arrange in numerical order simultaneously, drop into more manpower, and can there is certain error rate.
In addition, sample, in the process putting into liquid nitrogen or melt at sample, often occurs that pipe lid is tight or by the situation that liquid nitrogen flicks, causes sample to spill, obscures or the generation repeatedly of cross pollution.
Therefore, be necessary to provide a kind of device that can realize fast freeze-thaw sample.
Summary of the invention
For problems of the prior art, the object of the present invention is to provide a kind of device for fast freeze-thaw sample.
The technical scheme that the present invention takes is:
For a device for fast freeze-thaw sample, comprise freeze-drying plate and freeze-drying frame; Wherein, described freeze-drying plate is individual layer thin plate, and freeze-drying plate offers eyelet, and described eyelet is equipped with the centrifuge tube of test specimen for carrying; Described freeze-drying frame is connected to form by fixed support, baffle plate, slot and front fixed bar, each fixed support is parallel to each other and arranges perpendicular to bottom surface, each fixed support isometry position place is welded with baffle plate, baffle plate next-door neighbour downside is welded with slot, described slot is used for the freeze-drying plate that sample is housed to insert freeze-drying frame, and freeze-drying plate is fixed in the middle of freeze-drying frame by front fixed bar.
Further, the eye diameter on described freeze-drying plate is 1cm-2cm.
Further, in described device, freeze-drying plate can be one or more; Described freeze-drying plate is parallel to bottom surface and inserts in slot.
Take for convenience, further, two diagonal angles of described freeze-drying plate are also provided with outstanding fixing button.
Distance between described slot and baffle plate is higher than the height of fixing button.
For ensureing freeze thawing effect, preferably, described baffle plate is set to orifice plate; Hole position one_to_one corresponding on its Kong Weiyu freeze-drying plate, and pore size is no more than 1cm.
Further, described fixed support is set to L-type structure.
Further, described fixed support is set to four, after two support bracket fastened L-types outstanding towards inner side, before two support bracket fastened L-types outstanding toward the outer side.
Described freeze-drying frame can be one or more layers, generally can be set to 4-6 layer.
Further, described front fixed bar is inclined to set, and the two ends up and down of front fixed bar are fastened on a support bracket fastened top and the support bracket fastened bottom of another root respectively.
Compared with prior art, the invention provides a kind of device being applicable to fast freeze-thaw sample multigelation, described freeze-drying plate is set to individual layer steel plate, offers the eyelet of multiple aligned transfer above, can directly and centrifuge tube with the use of, freeze-drying frame comprises fixed support, baffle plate, slot and front fixed rod structure, have light, the advantage of firm and durable, be particularly useful for the multigelation of batch samples, have easy and simple to handle, the freeze thawing time is fast, error rate is low, can save the advantages such as artificial.Be convenient to the overall freeze thawing of sample, reduce the loss of sample, decrease the labour expenditure repeatedly sampling, put sample, raise the efficiency and accuracy.
Accompanying drawing explanation
Fig. 1 is the structural representation of the freeze thawing freeze-drying plate of hollow of the present invention;
Fig. 2 is the structural representation of the freeze thawing freeze-drying plate piling sample in the present invention;
Fig. 3 is the schematic top plan view of four bracing frames in the present invention;
Fig. 4 is the structural representation of the freeze-drying frame of freeze thawing sample in the present invention;
Fig. 5 is the structural representation of the freeze thawing freeze-drying frame piling sample in the present invention;
Wherein, 1, eyelet; 2, fixing button; 3, fixed support; 4, baffle plate; 5, slot; 6, front fixed bar; 7, two fixed supports below; 8, two fixed supports above; 9, freeze-drying box.
Embodiment
The present invention is further illustrated below in conjunction with accompanying drawing.
Embodiment 1
As shown in Figure 1, described freeze-drying plate is set to single thin layer steel plate, freeze-drying plate offers eyelet 1, and namely freeze-drying plate offers the eyelet 1 that diameter is 1.1cm, the diameter than hole eye 1 that the centrifuge tube of test specimen is housed is smaller, number and sample well eyelet 1 one_to_one corresponding.
Two diagonal angles of described freeze-drying plate are also provided with outstanding fixing button 2; The centrifuge tube that test specimen is housed puts into freeze-drying plate (as shown in Figure 2) by eyelet 1.
Embodiment 2
As shown in Figure 4, a kind of device for fast freeze-thaw sample, comprise freeze-drying plate and freeze-drying frame, described freeze-drying plate is set to single thin layer steel plate, and freeze-drying plate offers the eyelet 1 that diameter is 1cm-2cm, the diameter than hole eye 1 that the centrifuge tube of test specimen is housed is smaller, number and sample well eyelet 1 one_to_one corresponding, the centrifuge tube that test specimen is housed puts into freeze-drying plate by eyelet 1, and two diagonal angles of described freeze-drying plate are provided with outstanding fixing button 2, and instant freeze dried plate takes out and puts into.
Described freeze-drying erection is equipped with 4 layers, and freeze-drying frame is assembled by fixed support 3, baffle plate 4, slot 5 and front fixed bar 6 to form.The isometry position of fixed support 3 is welded with baffle plate 4, and baffle plate 4 is orifice plate, and the pore size on baffle plate 4 is no more than 1cm, facilitates liquid nitrogen to pass lower baffle plate 4, can play again the effect stoping centrifuge tube to float simultaneously.Baffle plate 4 is close to downside and is welded with slot 5, and the freeze thawing freeze-drying plate that sample is housed inserts in freeze-drying frame by slot 5, and the distance between slot 5 and baffle plate 4 is higher than the height of fixing button 2.
Fixed support 3 is set to four, adopts four fixed supports 3 to support, and does not adopt back up pad, can alleviate the weight of freeze-drying frame on the one hand, also can reduce the energy absorption of frozen-thaw process on the other hand, reduces the consumption of liquid nitrogen, accelerates freeze thawing speed.
Fixed support 3 is set to L-type structure, after the turning of two fixed supports 7 towards inner side, freeze-drying plate can be stopped; Two turnings of two fixed supports 8 toward the outer side above, the insertion of instant freeze dried plate and taking-up (as shown in Figure 3).
The front side of freeze-drying frame inserts front fixed bar 6 from top to bottom, front fixed bar 6 is inclined to set, the two ends up and down of front fixed bar 6 are fastened on the top of a fixed support 3 and the bottom of another root fixed support 3 respectively, freeze-drying plate is fixed in the middle of freeze-drying frame (as shown in Figure 5), during mobile freeze-drying frame, freeze-drying plate and sample can not from landings freeze-drying frame.
Described device can directly be put in foam box or in bigbore liquid nitrogen container after loading centrifuge tube, the freeze thawing (as shown in Figure 5) of a large amount of sample of complete fulfillment.
The above is not limitation of the present invention; be noted that for those skilled in the art; under the prerequisite not departing from essential scope of the present invention; can also make some changes, remodeling, interpolation or replacement, these improvements and modifications also should be considered as protection scope of the present invention.
Claims (10)
1. for a device for fast freeze-thaw sample, it is characterized in that, comprise freeze-drying plate and freeze-drying frame; Wherein, described freeze-drying plate is individual layer thin plate, and freeze-drying plate offers eyelet, and described eyelet is equipped with the centrifuge tube of test specimen for carrying; Described freeze-drying frame is connected to form by fixed support, baffle plate, slot and front fixed bar, each fixed support is parallel to each other and arranges perpendicular to bottom surface, each fixed support isometry position place is welded with baffle plate, baffle plate next-door neighbour downside is welded with slot, described slot is used for the freeze-drying plate that sample is housed to insert freeze-drying frame, and freeze-drying plate is fixed in the middle of freeze-drying frame by front fixed bar.
2. device according to claim 1, is characterized in that, the eye diameter on described freeze-drying plate is 1cm-2cm.
3. device according to claim 1, is characterized in that, described freeze-drying plate is one or more; Described freeze-drying plate is parallel to bottom surface and inserts in slot.
4. the device according to claim 1-3 any one, is characterized in that, two diagonal angles of described freeze-drying plate are provided with outstanding fixing button.
5. device according to claim 4, is characterized in that, the distance between described slot and baffle plate is higher than the height of fixing button.
6. device according to claim 1, is characterized in that, described baffle plate is set to orifice plate; Hole position one_to_one corresponding on its Kong Weiyu freeze-drying plate, and pore size is no more than 1cm.
7. device according to claim 1, is characterized in that, described fixed support is set to L-type structure.
8. device according to claim 7, is characterized in that, described fixed support is set to four, after two support bracket fastened L-types outstanding towards inner side, before two support bracket fastened L-types outstanding toward the outer side.
9. device according to claim 1, is characterized in that, described freeze-drying erection is equipped with 4-6 layer.
10. device according to claim 1, is characterized in that, described front fixed bar is inclined to set, and the two ends up and down of front fixed bar are fastened on a support bracket fastened top and the support bracket fastened bottom of another root respectively.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610055531.XA CN105547799A (en) | 2016-01-27 | 2016-01-27 | Device for rapidly freezing and thawing samples |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610055531.XA CN105547799A (en) | 2016-01-27 | 2016-01-27 | Device for rapidly freezing and thawing samples |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105547799A true CN105547799A (en) | 2016-05-04 |
Family
ID=55827141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610055531.XA Pending CN105547799A (en) | 2016-01-27 | 2016-01-27 | Device for rapidly freezing and thawing samples |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105547799A (en) |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050029914A1 (en) * | 2003-08-05 | 2005-02-10 | Zhenming Wang | Highly flexible and accessible freezer drawer rack |
| CN102870765A (en) * | 2012-04-12 | 2013-01-16 | 湖南省畜牧兽医研究所 | Device for freezing semen or cell and freezing method |
| CN202966941U (en) * | 2012-12-12 | 2013-06-05 | 宋芳琳 | Specimen storage box |
| CN203030309U (en) * | 2013-01-06 | 2013-07-03 | 王辉 | New type test tube support |
| CN203047805U (en) * | 2013-01-09 | 2013-07-10 | 江苏和泽生物科技有限公司 | Novel cryopreserved shelf |
| KR101393257B1 (en) * | 2012-03-21 | 2014-05-08 | 홍경만 | A sample box retractor and liquid gas frozen storage tank having the same |
| CN203928690U (en) * | 2014-04-17 | 2014-11-05 | 浙江海洋学院 | Freezing sample apparatus for placing |
| CN204490854U (en) * | 2015-01-12 | 2015-07-22 | 云舟生物科技（广州）有限公司 | A kind of freezing frame stored in a large number for DNA library |
-
2016
- 2016-01-27 CN CN201610055531.XA patent/CN105547799A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050029914A1 (en) * | 2003-08-05 | 2005-02-10 | Zhenming Wang | Highly flexible and accessible freezer drawer rack |
| KR101393257B1 (en) * | 2012-03-21 | 2014-05-08 | 홍경만 | A sample box retractor and liquid gas frozen storage tank having the same |
| CN102870765A (en) * | 2012-04-12 | 2013-01-16 | 湖南省畜牧兽医研究所 | Device for freezing semen or cell and freezing method |
| CN202966941U (en) * | 2012-12-12 | 2013-06-05 | 宋芳琳 | Specimen storage box |
| CN203030309U (en) * | 2013-01-06 | 2013-07-03 | 王辉 | New type test tube support |
| CN203047805U (en) * | 2013-01-09 | 2013-07-10 | 江苏和泽生物科技有限公司 | Novel cryopreserved shelf |
| CN203928690U (en) * | 2014-04-17 | 2014-11-05 | 浙江海洋学院 | Freezing sample apparatus for placing |
| CN204490854U (en) * | 2015-01-12 | 2015-07-22 | 云舟生物科技（广州）有限公司 | A kind of freezing frame stored in a large number for DNA library |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN205593836U (en) | A freeze -drying board and device for rapid freeze thawing sample | |
| CN105547799A (en) | Device for rapidly freezing and thawing samples | |
| CN201788957U (en) | Silicon wafer slide jig | |
| CN207221827U (en) | A kind of large-capacity multipurpose way rocking equipment | |
| CN202624299U (en) | Reed transporting car | |
| CN203003849U (en) | Tray suspension device | |
| CN207712729U (en) | A kind of PC prefabricated components container | |
| CN204150502U (en) | A kind of flexible soft tank | |
| CN111207572A (en) | Shelf for drying test tubes | |
| CN206006538U (en) | Container cabinet | |
| CN218617862U (en) | Low temperature sample storage box | |
| CN214514666U (en) | Liquid transfer device for chemical quality inspection | |
| CN204022823U (en) | Stent-type cell filtration sieves | |
| CN211755137U (en) | Liquid separation funnel rack | |
| CN202770118U (en) | Fixing support frame used for drying substrate in large size | |
| CN207439756U (en) | A kind of field water sampling device | |
| CN209518654U (en) | A kind of foldable flower holder | |
| CN203602321U (en) | Vertical encasement forking and transporting device of loader buckets | |
| CN211919566U (en) | Conveying mechanism for container inner container of container barrel | |
| CN206202963U (en) | A kind of pail for accommodating biological sample in liquid nitrogen container | |
| CN210458221U (en) | Cell is with isolated culture kit | |
| CN216305327U (en) | Scaffold for building engineering | |
| CN217136617U (en) | Stem cell cryopreservation device | |
| CN109455614B (en) | Hanging basket structure for hollow floor core mould | |
| CN203002413U (en) | Simple and easy multipurpose airing rack |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20160504 |